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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T7082 | HDAC8-IN-1 | HDAC | |
MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits ... | |||
T62171 | HDAC8/BRPF1-IN-1 | Others | |
HDAC8/BRPF1-IN-1 (Compound 23a) is a dual HDAC8 and BRPF1 inhibitor that acts on human HDAC8 (IC50: 443 nM) and human BRPF1 (Kd: 67 nM). HDAC8/BRPF1-IN-1 has low in vitro activity against HDAC1 and 6. | |||
T79082 | HDAC8-IN-4 | HDAC | |
HDAC8-IN-4 is a selective HDAC8 inhibitor, exhibiting inhibitory activity with IC50 values of 0.15 μM for HDAC8 and 12 μM for HDAC3 [1]. | |||
T61858 | HDAC8-IN-3 | Others | |
HDAC8-IN-3 (compound P19) is a highly potent inhibitor of HDAC8, displaying an IC50 value of 9.3 μM and producing thermal stabilization. Moreover, HDAC8-IN-3 exhibits cytotoxicity and induces apoptosis specifically in le... | |||
T61727 | HDAC6/8/BRPF1-IN-1 | Others | |
HDAC6/8/BRPF1-IN-1 is a dual inhibitor that targets HDAC6, HDAC8, and the bromodomain and PHD finger containing protein 1 (BRPF1). It exhibits inhibitory activity against HDAC1, HDAC6, and HDAC8 with IC50 values of 797 n... | |||
T78861 | HDAC8-IN-5 | HDAC | |
HDAC8-IN-5 (Compound 6a), with an inhibitory concentration (IC50) of 28 nM, is a potent HDAC8 inhibitor suitable for cancer research [1]. | |||
T61524 | Tubulin/HDAC-IN-1 | Others | |
Tubulin/HDAC-IN-1 is a compound that functions as a dual inhibitor for tubulin and HDAC-IN-1. It achieves this by interacting with tubulin through CH/π interaction and with HDAC8 through hydrogen bond interaction. This c... | |||
T61549 | HDAC8-IN-2 | Others | |
HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC50 values of 0.27 μM and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. It effectively kills schistosome larvae and ... | |||
T62327 | HDAC2-IN-1 | Others | |
HDAC2-IN-1 (Compound 17) is an orally active, competitive HDAC2 inhibitor (IC50: 0.5 μM) that crosses the blood-brain barrier. HDAC2-IN-1 also inhibits HDAC1 (IC50: 1.61 μM) and HDAC8 (IC50: 0.98 μM). | |||
T60856 | HDAC6-IN-9 | Others | |
HDAC6-IN-9 (compound 12c) is a potent and selective inhibitor of HDAC6 with anti-proliferative activities. The IC 50 values of HDAC6-IN-9 for HDAC6, HDAC1,HDAC3, HDAC8, and HDAC10 is 4.2, 11.8, 15.2, 139.6, and 21.3 nM, ... | |||
T63543 | HDAC/Top-IN-1 | Others | |
HDAC/Top-IN-1 is a broad-spectrum, orally active dual HDAC/Top inhibitor that acts on HDAC1 (IC50: 0.036 μM), HDAC2 (IC50: 0.14 μM), HDAC3 (IC50: 0.059 μM), HDAC6 (IC50: 0.089 μM) and HDAC8 ( IC50: 9.8 μM). HDAC/Top-IN-1... | |||
T61139 | HDAC6-IN-3 | Others | |
HDAC6-IN-3 (Compound 14) is a potent anti-prostate cancer agent that acts as an orally active inhibitor of HDAC6. It has IC50 values ranging from 0.02-1.54 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10. Additional... | |||
T78769 | HDAC6-IN-17 | HDAC | |
HDAC6-IN-17 (compound 5b) is a potent inhibitor of HDAC6, exhibiting IC50 values of 150 nM for HDAC6, 1400 nM for HDAC8, and 2300 nM for HDAC4. It demonstrates cytotoxic activity against human cancer cell lines and is ut... | |||
T63509 | Top/HDAC-IN-1 | Others | |
Top/HDAC-IN-1 is a dual topoisomerase (Top)/HDAC inhibitor that acts on HDAC1 (IC50: 18 nM), HDAC2 (IC50: 230 nM), HDAC3 (IC50: 790 nM), HDAC6 (IC50: 87 nM) and HDAC8 (IC50: 5250 nM). Top/HDAC-IN-1 exhibited potent antit... | |||
T61451 | NMDAR/HDAC-IN-1 | Others | |
NMDAR/HDAC-IN-1 (Compound 9d) is a potent dual inhibitor of N-methyl-D-aspartate receptors (NMDARs) and histone deacetylases (HDACs). It exhibits a high affinity (Ki = 0.59 μM) for NMDARs, while demonstrating significant... | |||
T75021 | SZUH280 | Others | |
SZUH280 is a potent, selective PROTAC (proteolysis targeting chimera) HDAC8 (histone deacetylase 8) degrader, demonstrating a DC50 of 0.58 μM in A549 cells. It induces apoptosis in cancer cells and impedes DNA damage rep... | |||
T78880 | Tubulin/HDAC-IN-3 | Others | |
Tubulin/HDAC-IN-3 (compound 12a) serves as a potent dual inhibitor of tubulin polymerization and HDAC1/8, exhibiting IC50 values of 5.4 μM for tubulin polymerization, and 0.155 and 0.177 μM for HDAC1 and HDAC8, respectiv... | |||
T79371 | HDAC-IN-62 | Autophagy | |
HDAC-IN-62 (Compound 5), an HDAC inhibitor, exhibits IC50 values of 0.78, 1.0, and 1.2 μM for HDAC6, HDAC8, and HDAC11, respectively. This compound suppresses microglial activation via autophagy induction and reduces nit... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-01333 | HDAC8 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
HDAC8 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68 kDa and the accession number is Q9BY41-1. | |||
TMPY-02317 | HDAC8 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
HDAC8 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 43.1 kDa and the accession number is Q8VH37-1. | |||
TMPY-04451 | AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&... | |||
TMPY-03878 | Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-02501 | CD3D & CD3E Heterodimer Protein, Human, Recombinant | Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-03745 | CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-02112 | FGFR4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1. | |||
TMPY-02335 | OSMR Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
OSMR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 83.7 kDa and the accession number is O70458-1. | |||
TMPY-00322 | DEC-205 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp... | |||
TMPY-02779 | Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) | Human | Baculovirus Insect Cells |
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoant... | |||
TMPY-02115 | R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His) | Human | HEK293 Cells |
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in devel... | |||
TMPY-04529 | EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) | Human | Baculovirus Insect Cells |
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.1 kDa and the accession number is P00533-1. | |||
TMPY-04261 | CD64 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD64 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32 kDa and the accession number is P12314-1. | |||
TMPY-01147 | R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1. | |||
TMPY-00464 | M-CSF/CSF1 Protein, Mouse, Recombinant | Mouse | HEK293 Cells |
M-CSF/CSF1 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P07141-1. | |||
TMPY-02412 | ENO1 Protein, Human, Recombinant (His) | Human | E. coli |
ENO1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 49.3 kDa and the accession number is P06733-1. | |||
TMPY-01920 | BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) | Human | HEK293 Cells |
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9Y275-1. | |||
TMPY-00735 | Cathepsin S Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Cathepsin S Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is P25774-1. | |||
TMPY-06074 | B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 Cells |
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A2K5U6P5-1. | |||
TMPY-01725 | Leptin Receptor Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Leptin Receptor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is P48357-1. | |||
TMPY-03956 | Fas Ligand Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su... | |||
TMPY-00414 | LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1. | |||
TMPY-01082 | Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G/RSV-G Protein (95% Homology) (His) | RSV | HEK293 Cells |
Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G/RSV-G Protein (95% Homology) (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession num... | |||
TMPY-06076 | LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1. | |||
TMPY-03967 | BTN3A3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1. | |||
TMPY-02154 | FAP Protein, Human, Recombinant (His) | Human | HEK293 Cells |
FAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1. | |||
TMPY-00756 | FGF-1 Protein, Human, Recombinant | Human | E. coli |
FGF-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is P05230-1. | |||
TMPY-05201 | Siglec-2/CD22 Protein, Human, Recombinant | Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.2 kDa and the accession number is P20273-1. | |||
TMPY-05827 | PD-L2 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
PD-L2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 48.93 kDa and the accession number is Q9BQ51-1. | |||
TMPY-01139 | PDGFRA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1. | |||
TMPY-05354 | CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 43.7 kDa and the accession number is P10747-1. | |||
TMPY-00820 | IgG1 Fc Protein, Human, Recombinant (C103S) | Human | HEK293 Cells |
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1. | |||
TMPY-02312 | CSF3R/G-CSFR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CSF3R/G-CSFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68 kDa and the accession number is Q99062-1. | |||
TMPY-05220 | TSLP Protein, Human, Recombinant (R127A & R130S, His) | Human | HEK293 Cells |
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1. | |||
TMPY-03273 | IL-18 Protein, Mouse, Recombinant | Mouse | E. coli |
IL-18 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.2 kDa and the accession number is P70380-1. | |||
TMPY-01410 | IL-3R alpha/CD123 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
IL-3R alpha/CD123 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P26951-1. | |||
TMPY-01573 | SIRP alpha Protein, Human, Recombinant (G75A, His) | Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (G75A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is P78324-1. | |||
TMPY-03782 | Albumin Protein, Human, Recombinant | Human | P. pastoris (Yeast) |
Albumin Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 66.4 kDa and the accession number is P02768-1. | |||
TMPY-01968 | CD32A Protein, Human, Recombinant (167 His, His) | Human | HEK293 Cells |
CD32A Protein, Human, Recombinant (167 His, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P12318-1. | |||
TMPY-01389 | HER3/ERBB3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1. | |||
TMPY-01395 | CTHRC1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CTHRC1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.5 kDa and the accession number is Q96CG8-1. | |||
TMPY-06873 | FLT3 Ligand Protein, Human, Recombinant | Human | E. coli |
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1. | |||
TMPY-00843 | IL-25/IL17E Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
IL-25/IL17E Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45 kDa and the accession number is Q9H293-1. | |||
TMPY-04153 | RNF43 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr... | |||
TMPY-01209 | IL-7R alpha/CD127 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
IL-7R alpha/CD127 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P16871-1. | |||
TMPY-01349 | ICAM-1/CD54 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
ICAM-1/CD54 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.7 kDa and the accession number is P13597-1. | |||
TMPY-00742 | EGFR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
EGFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is P00533-1. | |||
TMPY-03215 | FLT3 Ligand Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
FLT3 Ligand Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.2 kDa and the accession number is P49771-1. | |||
TMPY-00694 | Carbonic Anhydrase 12 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Carbonic Anhydrase 12 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is O43570-1. | |||
TMPY-01076 | Gp130/IL6ST Protein, Human, Recombinant (His & hFc) | Human | HEK293 Cells |
gp130/IL6ST Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 96 kDa and the accession number is P40189-1. | |||
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