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T61683 |
Antiparasitic agent-9
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Antiparasitic agent-9 (compound 47) is a highly active and orally administered antiparasitic agent, exhibiting potent antiparasitic efficacy against the human parasite [1]. |
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T83025 |
Antiparasitic agent-19
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Antiparasitic Agent-19 (Compound 40) is a broad-spectrum antiparasitic with minimal toxicity to Trypanosoma brucei, Leishmania infantum, and Trypanosoma cruzi [1]. |
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T61160 |
Antiparasitic agent-2
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Antiparasitic agent-2 (compound 8a) exhibits potent antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi), with IC50s of 7.28 μM and 2.30 μM, respectively. Additionally, it dem... |
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T83024 |
Antiparasitic agent-20
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|
Parasite
|
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Antiparasitic Agent-20 (Compound 1p) exhibits broad-spectrum activity as a parasitic inhibitor, demonstrating efficacy against T. brucei and T. cruzi with EC50 values of 0.09 µM and 14.1 µM, respectively [1]. |
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T79415 |
Antiparasitic agent-18
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Parasite
|
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Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T. brucei (EC 50 =0.4 µM), T. cruzi (EC 50 =0.21 µM), and L. donovani (EC 50 =0.26 µM) [1]. |
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T61538 |
Antiparasitic agent-10
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Antiparasitic agent-10 (Compound 94) is a potent anti-parasitic agent specifically designed to target and combat parasitic infections. It demonstrates notable anti-schistosomal activity, particularly against adults of Sc... |
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T61221 |
Antiparasitic agent-8
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Antiparasitic agent-8 (Compound 9) exhibits potent antiparasitic activity against Hymenolepis nana, while demonstrating low levels of cytotoxicity [1]. |
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T61245 |
Antiparasitic agent-7
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Antiparasitic agent-7 (compound 5d) displays specific antiparasitic activity against Leishmania infantum (L. infantum), exhibiting an IC50 value of 2.85 μM. Additionally, Antiparasitic agent-7 demonstrates cytotoxicity a... |
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T74773 |
Antiparasitic agent-14
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Antiparasitic Agent-14 is a potent antiparasitic compound with demonstrated cytotoxicity and antiparasitic activity, effectively inhibiting the growth of trypomastigote and amastigote forms [1]. |
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T61001 |
Antiparasitic agent-6
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Antiparasitic agent-6 (compound 5b) shows selectively antiparasitic activity against Leishmania infantum (L. infantum) (IC 50 = 3.89 μM). Antiparasitic agent-6 also exhibits certain cytotoxicity against HepG2 with a CC50... |
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T60519 |
Antiparasitic agent-4
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Antiparasitic agent-4 (compound 4q) exhibits high antiparasitic activity with IC50 of 8.51 μM for Leishmania infantum (L. infantum) and IC50 of 2.20 μM for Trypanosoma cruzi ( T. cruzi ). Antiparasitic agent-4 is also cy... |
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T61641 |
Antiparasitic agent-5
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Antiparasitic agent-5 (compound 8h) exhibits potent selectivity as an antiparasitic agent against Leishmania infantum (L. infantum), with an IC50 value of 2.50 μM. Additionally, this compound displays cytotoxic effects o... |
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T78966 |
Antiparasitic agent-17
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Parasite
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Antiparasitic Agent-17 (compound 5u), an orally active antiparasitic, demonstrates inhibition against both Chloroquine-sensitive (Pf3D7) and Chloroquine-resistant (PfK1) strains, with IC50 values of 0.96 μM and 1.67 μM, ... |
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T5471 |
GUANABENZ
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Adrenergic Receptor
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GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist. |
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T21957 |
Guanabenz hydrochloride
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NE56490 |
Adrenergic Receptor
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Guanabenz hydrochloride (NE56490) is an orally active α2-adrenoceptor agonist with hypotensive effects. |
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T7093 |
Rafoxanide
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CDK
,
Parasite
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Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations. |
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T6275 |
Obatoclax Mesylate
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Obatoclax,GX15-070 |
BCL
,
Parasite
,
Autophagy
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Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3. |
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T10328 |
Anti-parasitic agent 3
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Others
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Anti-parasitic agent 3 is an anti-parasitic agent active against drug-resistant parasites. |
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T2160 |
Suramin Sodium Salt
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BAY-205,Suramin hexasodium salt,NF-060 |
Apoptosis
,
Phosphatase
,
SARS-CoV
,
Sirtuin
,
Reverse Transcriptase
,
Topoisomerase
,
Parasite
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Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth f... |
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T38724 |
Modoflaner
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Parasite
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Modoflaner is an antiparasitic (veterinary use). |
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T16965 |
Symetine
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L 16726 |
Parasite
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Symetine（L 16726） is a small molecule compound with antiparasitic activity that can be used to study amoebic liver abscesses in guinea pigs. |
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T0494 |
Tetramisole hydrochloride
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R-829,DL-Tetramisole hydrochloride,(±)-Tetramisole hydrochloride,Tetramisole HCl |
Phosphatase
,
Dehydrogenase
,
Antibiotic
,
Parasite
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Tetramisole hydrochloride (Tetramisole HCl) inhibits alkaline phosphatase and is a high-purity antiparasitic agent. |
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T60092 |
CHEMBL1276927
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N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide,N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide |
Antibacterial
,
Parasite
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CHEMBL1276927 (N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide) shows antibacterial and antiparasitic activities against Chlamydia pneumoniae and Leishmania donovani. |
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T0942 |
Quinacrine dihydrochloride
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Mepacrine dihydrochloride,SN-390,Quinacrine 2HCl |
Apoptosis
,
Mitophagy
,
DNA
,
Phospholipase
,
Parasite
,
Autophagy
,
Histamine Receptor
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Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities. |
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T0876 |
Clioquinol
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Chinoform,Iodochlorhydroxyquin |
Mitophagy
,
Antibiotic
,
Autophagy
,
Antifungal
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Clioquinol (Iodochlorhydroxyquin) is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities. |
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T12154L |
N-Desethyl amodiaquine dihydrochloride
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Parasite
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N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively. |
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T78605 |
CpCDPK1/TgCDPK1-IN-1
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Bcr-Abl
,
Src
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CpCDPK1/TgCDPK1-IN-1 is a potent dual inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections and cryptosporidiosis. |
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T2112 |
Fexinidazole
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HOE 239 |
Others
,
Parasite
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Fexinidazole (HOE 239) is an antiparasitic agent. It has activity against Trypanosoma cruzi, Tritrichomonas foetus, Trichomonas vaginalis, Entamoeba histolytica, Trypanosoma brucei, and Leishmania donovani. The biologica... |
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T28174 |
Niridazole
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BA32644,BA-32644,Ambilhar,BA 32644 |
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Niridazole (Ambilhar) is an antiparasitic compound belonging to nitroimidazoles. Niridazole is primarily used to treat schistosomiasis, which kills the parasite by interfering with its metabolism. Niridazole rapidly conc... |
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T50059 |
6-ethenylquinoline
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Others
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6-ethenylquinoline is a structurally unique aromatic heterocyclic compound that is an important intermediate in the production of other aromatic compounds. It has also been used as a starting material for the synthesis o... |
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T27278 |
Epsiprantel
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Epsiprantel is an antiparasitic for canine worms. |
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T10551 |
Bithionol sulfoxide
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Others
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Bithionol sulfoxide is a clinically approved antiparasitic drug with the inhibitory against solid tumor growth in several preclinical cancer models. |
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T28976 |
Tigolaner
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Tigolaner is a antiparasitic drug candidate for veterinary use. |
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T23731 |
Amoscanate
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GO 9333,CCRIS 4111,Ciba 9333 GO,C 9333 GO,CGP 4540 |
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Amoscanate is an antiparasitic agent. It is highly effective in animals against the four major species of schistosomes which infect humans. |
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T38755 |
Rafoxanide 13C6
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Rafoxanide 13C6 is a labeled Rafoxanide . Rafoxanide is a salicylanilide used as an antiparasitic agent. |
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T74537 |
Antifungal agent 26
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Pradimicin A derivative 26 exhibits antifungal, antiviral, and antiparasitic properties by attaching to d-mannose (Man)-rich glycans in pathogenic organisms [1]. |
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T79301 |
Anticancer agent 140
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Parasite
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Compound 140 (Compd 3) exhibits potential anticancer and antiparasitic activities [1]. |
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T12154 |
N-Desethyl amodiaquine
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Parasite
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N-Desethyl amodiaquine is an antiparasitic agent and the major bioactive amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively. |
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T75500 |
Batzelladine D
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Batzelladine D, also known as Compound 1, functions as an inhibitor of the Pdr5p transporter's catalytic and functional activities, demonstrating inhibitory action against Pdr5p ATPase activity with an IC50 value of 7.1 ... |
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T37748 |
Ivermectin B1b
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Ivermectin B1b is the minor component . It produces antiparasitic activity by binding to glutamate-gated chloride channels expressed on nematode neurons and pharyngeal muscle cells, inducing irreversible channel opening ... |
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T63610 |
SPR7
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SPR7 is a potent and selective rhodesain inhibitor (Ki: 0.51 nM). SPR7 exhibited antiparasitic effects against T. b. brucei (EC50: 1.65 μM). |
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T11013 |
Dextrorotation nimorazole phosphate ester
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Others
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Dextrorotation nimorazole phosphate ester is an anti-anaerobic and anti-parasitic agent. D-morpholine ornidazole organic phosphate is a newly developed, highly efficient, well-tolerated fourth-generation nitroimidazole d... |
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T41278 |
Obatoclax
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Obatoclax (GX15-070), a pan-BCL-2 family proteins inhibitor and BH3 mimetic, exhibits a binding affinity (K_i) of 220 nM for BCL-2. It promotes autophagy-dependent cell death and cyclin D1 degradation via the proteasome.... |
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T76471 |
Lactoferricin, bovine
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Lactoferricin, bovine is an iron-binding glycoprotein derived from the acidic hydrolysis of bovine lactoferrin. Lactoferricin, bovine has bactericidal, antifungal, antiparasitic, antitumor, antiviral, and immunomodulator... |
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T60465 |
Anti-infective agent 2
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Anti-infective agent 2 (compound 3k) is an antiprotozoal and antimycobacterial agent. Anti-infective agent 2 exhibits antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC 50 values of 0.07 and ... |
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T63488 |
TCMDC-135051 hydrochloride
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TCMDC-135051 hydrochloride is a potent, highly selective, low off-target toxicity inhibitor of the protein kinase PfCLK3. TCMDC-135051 hydrochloride blocks the trophozoite to lysosome transition, disrupts transcription a... |
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T64139 |
TCMDC-135051 TFA
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TCMDC-135051 TFA is a potent, highly selective, low off-target toxicity protein kinase PfCLK3 inhibitor that exhibits antiparasitic effects with an EC50 value of 320 nM. TCMDC-135051 TFA blocks the trophozoite to lytic t... |
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T17257 |
WR99210
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DHFR
,
Antifolate
,
Antibacterial
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WR99210 is a potent, orally available and less toxic dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 has good antiparasitic activity against P. vivax and P. falciparum strains (including P. falciparum s... |
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T60468 |
Anti-infective agent 3
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Anti-infective agent 3 is an antiprotozoal and antimycobacterial agent. Anti-infective agent 3 (compound 3l) exhibits antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC 50 values of 0.47 and ... |
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T60315 |
Anti-infective agent 1
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Anti-infective agent 1 (compound 3a) serves as a potent, selective antiprotozoal and antimycobacterial compound. It showcases antiparasitic efficacy against P. falciparum and T. brucei rhodesiense, demonstrating IC50 val... |
