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阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T22309	2,5-Dimethyl-3(2H)-furanone	2,5-Dimethyl-2,3-dihydrofuran-3-one	Others
	2,5-Dimethyl-3(2H)-furanone (2,5-Dimethyl-2,3-dihydrofuran-3-one) is a non-genotoxic flavoring substance [1].		Others
T20039	7-Methyladenine	NSC7857,NSC-7857,NSC 7857	Others
	7-Methyladenine (NSC-7857) can be used as a marker of exposure to exogenous and carcinogenic methylating agents.		Others
T19445	N-Bis(2-hydroxypropyl)nitrosamine	Di(2-hydroxypropyl)nitrosamine,DHPN,Diisopropanolnitrosamine	Others
	N-Bis(2-hydroxypropyl)nitrosamine (DHPN) is a carcinogenic agent.		Others
T20760	Benzidine orange	DCC-1802,Polymo Orange GR,Oralith Orange PG,DCC 1802,DCC1802	Others
	Benzidine orange (DCC-1802) shows mutagenic and carcinogenic activity.		Others
T27112	Cytembena		DNA/RNA Synthesis
	Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.		DNA/RNA Synthesis
T19621	(S)-Metolachor	(S)-Metolachlor	Others
	(S)-Metolachor （(S)-Metolachlor） is a carcinogenic insecticide, a derivative of aniline, and is a frequent subject of research in agriculture and environmental protection.		Others
T32155	Indecainide	Ricainide,Ricainid,Decabid,Indecainidum,Indecainida	Others
	Indecainide (Ricainid) is a novel antiarrhythmic compound that is carcinogenic and can be used to study chronic stable ventricular arrhythmias secondary to coronary artery disease or cardiomyopathy.		Others
T0941	Cyclamic acid	Cyclamate,NSC 220327,Cyclohexylsulfamic acid	Others
	Cyclamic acid (NSC-220327) is an artificial sweetening agent, usually employed as Na or Ca salt (cyclamate). Use suspended in some countries, including USA, because of possible weak carcinogenic activity (disputed).		Others
T4169	N-Nitroso-N-methylurea	1-Methyl-1-nitrosourea,N-Methyl-N-nitrosourea,Methylnitrosourea	Others , DNA Alkylator/Crosslinker
	N-Nitroso-N-methylurea (Methylnitrosourea) is a nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.		Others , DNA Alkylator/Crosslinker
T2269	Pirinixic Acid	Wy-14643,NSC 310038	PPAR
	Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, carcinogenic Pirinixic acid is a peroxisome proliferator that activates specific peroxisome proliferator-activated recepto...		PPAR
T19859	Nicosulfuron	Milagro,Accent,Motivell	Others
	Nicosulfuron (Milagro) is a pesticide that works by inhibiting the acetolactate synthase enzyme. Nicosulfuron has not been found to induce mutagenic or carcinogenic effects. Nicosulfuron is a herbicide to protect corn cr...		Others
T17065	TFMB-(R)-2-HG		Others
	TFMB-(R)-2-HG is a carcinogenic factor in Acute myeloid leukemia (AML). TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cell differentiation in response to estrogen withdrawal.		Others
T33519	MTOB	α-keto-γ-Methylthiobutyric acid,KMBA,MTOB salt,4-methylthio 2-oxobutyric acid	Others
	MTOB (α-keto-γ-Methylthiobutyric acid) is a substrate for c-terminal binding protein (CtBP) that interferes with the carcinogenic activity of CtBP in cell culture and mice. It also actively regulates TCF-4 signaling, lea...		Others
T36696	DMBA
	7,12-Dimethylbenz[a]anthracene (DMBA) is a polycyclic aromatic hydrocarbon (PAH) that has been found in tobacco smoke and diesel exhaust and has carcinogenic activity.1,2It undergoes metabolic activation by numerous enzy...
T37514	Hydroxy Dimetridazole		Drug Metabolite
	Dimetridazole is a nitroimidazole-based compound with antibacterial and anticoccidial activity. It was once widely used in the treatment of parasitic infections in poultry, cattle, swine and farmed fish until suspected t...		Drug Metabolite
T19842	Aramite	BRN-2509312,BRN 2509312,BRN2509312
	Aramite is an insecticide that may have carcinogenic effects on mammals.
T23994	Dibenzo(a,i)pyrene	DB(a,i)p,Benzo(rst)pentaphene
	Dibenzo(a, i)pyrene is a polycyclic aromatic hydrocarbon with potent carcinogenic activity.
T26728	Aziridyl benzoquinone	A-139,A139,NSC-17262
	Aziridyl benzoquinone, an antineoplastic agent, has been studied as a mutagen and as a carcinogenic agent.
T32579	Lasiocarpine HCl	Lasiocarpine hydrochloride
	Lasiocarpine HCl is a hepatotoxic and carcinogenic food contaminant.
T23614	Achillin	NSC 156236,NSC156236,NSC-156236
	Achillin is a compound isolated from herbs. It may have anti-inflammatory and anti-carcinogenic activities.
T29596	Acetylaminofluorene-dG	dG-8-AAF,8-AAF dG,8 AAF-dG,8-AAF-dG
	Acetylaminofluorene-dG is a carcinogenic adduct which covalently binds DNA bases and promotes mutagenesis near the adduct site.
T39856	Purine riboside triphosphate	PTP,Purine riboside triphosphate
	Purine riboside triphosphate, a derivative of purine riboside, exhibits structural similarity to adenosine. This naturally occurring base analog possesses inhibitory effects on carcinogenic growth, particularly in cancer...
T23797	Bis(diazoacetyl)butane	1,4-Bis-diazoacetylbutane,Supermutagen,1,4-Bis(diazoacetyl)butane,DAB (mutagen)
	Bis(diazoacetyl)butane is a mutagen and traditionally related to radio-mimetic chemical mutagens due to the similarity of appearance of mutagenic action of this mutagen and physical mutagens. It also has anti-tumor and c...
T19979	Saccharin sodium hydrate	O-benzoic sulfimide sodium salt,Saccharin, sodium salt hydrate
	Saccharin, sodium salt hydrate is used in the food industry and for sweetening diabetes diet. It is also used as a synthetic sweet ignorance agent. Saccharin, sodium salt hydrate is the first generation′ synthetic sugar ...
TD0004	Celfinder nucleic acid gel stain 10,000× concentrate in DMSO
	Celfinder is a new kind of nucleic acid dye, which has the advantages of safety and sensitivity, and can be used as a dye for various kinds of nucleic acid electrophoresis.Unlike EB, which is highly carcinogenic, Celfind...
T1765	Erastin		Ferroptosis , VDAC
	Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner. Erastin has anti-tumor activity and acts selectively on tumor cells with RAS-carcinogenic mutations. The product...		Ferroptosis , VDAC
TD0005	SYBR GREEN II	SUPER Green II RNA gel stain 10,000× concentrate in DMSO (Electrophoresis Grade)
	1) Non-toxicity: belong to flower-stem dye, easy to biodegrade, no carcinogenic toxicity. 2) High sensitivity: at least 100pg ssDNA or RNA can be detected, which is 25 ~ 100 times higher than EB staining. 3) High SIGNal-...
T74784	LL-K8-22
	LL-K8-22 is a potent, selective, and durable dual degrader of CDK8-cyclin C, demonstrating DC50 values of 2.52 and 2.64 μM, respectively. This compound effectively suppresses STAT1 Ser 727 phosphorylation and inhibits ca...
T73862	Almurtide
	Almurtide (nor-MDP), a derivative of muramyl dipeptide, exhibits anti-inflammatory and anti-tumor properties. It demonstrates protective effects in mice against infections caused by Pseudomonas aeruginosa when administer...
T0976	Propoxur	Aprocarb,Propoxure,Baygon	AChR , Antifungal
	Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red b...		AChR , Antifungal

Compounds

2,5-Dimethyl-3(2H)-furanone

T22309

Synonym: 2,5-Dimethyl-2,3-dihydrofuran-3-one

Target: Others

7-Methyladenine

T20039

Synonym: NSC7857,NSC-7857,NSC 7857

Target: Others

N-Bis(2-hydroxypropyl)nitrosamine

T19445

Synonym: Di(2-hydroxypropyl)nitrosamine,DHPN,Diisopropanolnitrosamine

Target: Others

Benzidine orange

T20760

Synonym: DCC-1802,Polymo Orange GR,Oralith Orange PG,DCC 1802,DCC1802

Target: DNA/RNA Synthesis

(S)-Metolachor

T19621

Synonym: (S)-Metolachlor

Target: Others

Indecainide

T32155

Synonym: Ricainide,Ricainid,Decabid,Indecainidum,Indecainida

Target: Others

Cyclamic acid

T0941

Synonym: Cyclamate,NSC 220327,Cyclohexylsulfamic acid

Target: Others

N-Nitroso-N-methylurea

T4169

Synonym: 1-Methyl-1-nitrosourea,N-Methyl-N-nitrosourea,Methylnitrosourea

Target: Others, DNA Alkylator/Crosslinker

Pirinixic Acid

T2269

Synonym: Wy-14643,NSC 310038

Target: PPAR

Nicosulfuron

T19859

Synonym: Milagro,Accent,Motivell

Synonym: α-keto-γ-Methylthiobutyric acid,KMBA,MTOB salt,4-methylthio 2-oxobutyric acid

Hydroxy Dimetridazole

T37514

Synonym:

Target: Drug Metabolite

Aramite

T19842

Synonym: BRN-2509312,BRN 2509312,BRN2509312

Target:

Dibenzo(a,i)pyrene

T23994

Synonym: DB(a,i)p,Benzo(rst)pentaphene

Target:

Aziridyl benzoquinone

T26728

Synonym: A-139,A139,NSC-17262

Target:

Lasiocarpine HCl

T32579

Synonym: Lasiocarpine hydrochloride

Target:

Achillin

T23614

Synonym: NSC 156236,NSC156236,NSC-156236

Target:

Acetylaminofluorene-dG

T29596

Synonym: dG-8-AAF,8-AAF dG,8 AAF-dG,8-AAF-dG

Target:

Purine riboside triphosphate

T39856

Synonym: PTP,Purine riboside triphosphate

Target:

Bis(diazoacetyl)butane

T23797

Synonym: 1,4-Bis-diazoacetylbutane,Supermutagen,1,4-Bis(diazoacetyl)butane,DAB (mutagen)

Target:

Saccharin sodium hydrate

T19979

Synonym: O-benzoic sulfimide sodium salt,Saccharin, sodium salt hydrate

Target:

Celfinder nucleic acid gel stain *10,000× concentrate in DMSO*

Target: Ferroptosis, VDAC

SYBR GREEN II

TD0005

Synonym: SUPER Green II RNA gel stain *10,000× concentrate in DMSO* (Electrophoresis Grade)

Synonym: Aprocarb,Propoxure,Baygon

Target: AChR, Antifungal

カタログ番号	製品名	別名	ターゲット
T37101	1-Hydroxyanthraquinone		DNA/RNA Synthesis
	1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.		DNA/RNA Synthesis
T19412	Macrozamin		Others
	Macrozamin has carcinogenic, mutagenic, teratogenic and neurotoxic properties.Macrozamin is a natural product isolated from Cycads.		Others
T2805	Chlorogenic Acid	NSC-407296,3-O-Caffeoylquinic acid,Heriguard	Others , Influenza Virus , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , Endogenous Metabolite , Antibacterial
	Chlorogenic Acid (NSC-407296) is a naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats.
T7031	Aristolochic acid B	Aristolochic Acid II	DNA
	Aristolochic acid B (Aristolochic Acid II) is one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo, Aristolochic acid B sh...		DNA
T2901	Daidzin	NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside	Dehydrogenase , Reverse Transcriptase , Mitochondrial Metabolism
	Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
T2801	Aristolochic acid A	TR 1736,Aristolochin,Aristolochine,Aristolochic Acid I,Aristolochic Acid	Others , NF-κB
	Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort (Aristolochiaceae) family of plants.		Others , NF-κB
T1035	Hesperidin	Hesperetin 7-rutinoside,Cirantin	Apoptosis , Reactive Oxygen Species , Endogenous Metabolite , Autophagy
	Hesperidin (Cirantin) is a flavanone glycoside found in citrus fruits with antioxidant, anti-inflammatory, anti-carcinogenic, and antihypertensive and lipid-lowering activity.
TN1097	β-Boswellic acid	Beta-boswellic acid	Lipoxygenase , DNA/RNA Synthesis
	β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic activities.		Lipoxygenase , DNA/RNA Synthesis
T4115	Auraptene	7-geranyloxycoumarin	MMP , BACE
	Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le...		MMP , BACE
T5279	Ethylmalonic acid	alpha-Carboxybutyrate,2-Ethylmalonic acid	Others , Endogenous Metabolite
	Ethylmalonic acid (alpha-Carboxybutyrate) can be found in blood, cerebrospinal fluid (CSF), and urine, as well as in human fibroblasts, prostate, and skeletal muscle tissues. Moreover, ethylmalonic acid is found to be as...		Others , Endogenous Metabolite
T3746	Dimethyl phthalate	Solvanom,Avolin,Fermine	Others
	Dimethyl phthalate (Fermine) has many uses, including in solid rocket propellants, plastics, and insect repellants. Acute (short-term) exposure to dimethyl phthalate, via inhalation in humans and animals, results in irri...		Others
T3S2259	Methyl eugenol	4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether	GABA Receptor
	1. Methyl eugenol (4-allylveratrole) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its...		GABA Receptor
T13531	Aflatoxicol	Aflatoxin R0	Others
	Aflatoxin (Aflatoxin R0) is a mutagenic and carcinogenic mycotoxin derived from aflatoxin B1 through metabolic processes facilitated by Rhizopus spp.		Others
T31134	Cyclochlorotine	CCRIS 1316
	Cyclochlorotine is a mycotoxin produced by Penicillium insularum, which can cause liver injury and has carcinogenic properties.
TN4346	Jaconine		Others
	Jaconine, jacoline,jacobine, and jacozine, the hepatotoxic alkaloids, are potentially carcinogenic, mutagenic, and teratogenic and may pose health hazards to the human consumer.		Others
T16160	Musk tibetene	Musk tibetine	Others
			Others
TN4695	Odorine		Others
	Odorine has potent anti-carcinogenic effect by inhibiting both the initiation and promotion stages of two-stage skin carcinogenesis. It was found to inhibit the growth of the vinblastine-resistant KB cells by enhancing t...		Others
TN1359	Aflatoxin G1		TNF , NF-κB
	Aflatoxin G1 (AFG1 ), a member of the AF family with cytotoxic and carcinogenic properties, could cause DNA damage in alveolar type II (AT-II) cells and induce lung adenocarcinoma.		TNF , NF-κB
TN2926	3-Epicabraleahydroxylactone		Others
	3-Epicabraleahydroxylactone has anti-tumor promoting effect, it has anti-carcinogenic activity by the inhibitory effect on the induction of Epstein-Barr virus early antigen(EBV-EA) by the tumor promoter.		Others
T19096	2-Amino-5-phenylpyridine		Others
	2-Amino-5-phenylpyridine is a heterocyclic aromatic amine that is formed by pyrolysis of phenylalanine in proteins. It is in broiled sardines and is considered as potentially carcinogenic.		Others
TN4841	Ptaquiloside
	Ptaquiloside shows genotoxicity, it also has carcinogenic effects. Ptaquiloside has immunosuppressive effects, it reduces NK cell activities by enhancing metallothionein expression, which is prevented by selenium.
TN4151	Glyurallin A		Others
	Glyurallin A possesses an antigenotoxic effect against carcinogenic N-methyl-N-nitrosourea (MNU) for the first time, it is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention.		Others
T19165	8-Hydroxyguanine	8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine	Endogenous Metabolite
	8-Hydroxyguanine (8 Hydroxyguanine) is the major premutagenic damage produced by reactive oxygen species. It causes G-T and A-C substitutions.8-Hydroxyguanine is a biomarker for RNA oxidation and oxidative DNA damage.8-H...		Endogenous Metabolite
T77201	Rutin trihydrate
	Rutin (Rutoside) trihydrate, a natural flavonoid glycoside, exhibits multifaceted therapeutic properties, including antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic activities. Additionally, it has de...
TN3070	4beta-Hydroxywithanolide E		PARP , HSP , NF-κB , COX
	4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progression and develop into a dietary chemopreventive agent, it...		PARP , HSP , NF-κB , COX
T81484	Phorbol 12-tiglate
	Phorbol 12-tiglate, a derivative of Phorbol, which in turn is a hydrolyzed product of Croton oil, plays a role in tumor promotion through activation of protein kinase C. This compound and its related derivatives are empl...

天然物製品

1-Hydroxyanthraquinone

T37101

Synonym:

Target: DNA/RNA Synthesis

Synonym: NSC-407296,3-O-Caffeoylquinic acid,Heriguard

Target: Others, Influenza Virus, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, Antibacterial

Aristolochic acid B

T7031

Synonym: Aristolochic Acid II

Target: DNA

Daidzin

T2901

Synonym: NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside

Target: Dehydrogenase, Reverse Transcriptase, Mitochondrial Metabolism

Aristolochic acid A

T2801

Synonym: TR 1736,Aristolochin,Aristolochine,Aristolochic Acid I,Aristolochic Acid

Target: Others, NF-κB

Hesperidin

T1035

Synonym: Hesperetin 7-rutinoside,Cirantin

Target: Apoptosis, Reactive Oxygen Species, Endogenous Metabolite, Autophagy

β-Boswellic acid

TN1097

Synonym: Beta-boswellic acid

Target: Lipoxygenase, DNA/RNA Synthesis

Auraptene

T4115

Synonym: 7-geranyloxycoumarin

Target: MMP, BACE

Ethylmalonic acid

T5279

Synonym: alpha-Carboxybutyrate,2-Ethylmalonic acid

Target: Others, Endogenous Metabolite

Dimethyl phthalate

T3746

Synonym: Solvanom,Avolin,Fermine

Target: Others

Methyl eugenol

T3S2259

Synonym: 4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether

Target: GABA Receptor

Aflatoxicol

T13531

Synonym: Aflatoxin R0

Synonym: Musk tibetine

3-Epicabraleahydroxylactone

TN2926

Synonym:

Target: Others

2-Amino-5-phenylpyridine

Synonym: 8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine

Target: Endogenous Metabolite

4beta-Hydroxywithanolide E

TN3070

Synonym:

Target: PARP, HSP, NF-κB, COX

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00656	SULT1C2 Protein, Human, Recombinant (His)	Human	E. coli
	Sulfotransferase 1C2 (SULT1C2) is a cytosolic enzyme member of the Sulfotransferase 1 family. Human SULT1C2 is primarily expressed in the adult stomach, kidney and thyroid gland, and in the fetal kidney and liver. SULT1C...
TMPJ-00586	SULT1A2 Protein, Human, Recombinant (His)	Human	E. coli
	Sulfotransferase 1A2 (SULT1A2) is a member of the Sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. SULT1A2 is a cy...
TMPK-01485	HLA-A*01:01&B2M&DSG3 (YTDNWLAVY) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis. DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic fe...
TMPK-00726	DSG3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopatho...
TMPK-00871	DSG3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopatho...
TMPJ-01456	Mucin-17/MUC17 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin17 (MUC17) was m...
TMPY-03869	DCUN1D1 Protein, Human, Recombinant (His)	Human	E. coli
	DCUN1D1, also known as SCCRO, is part of an E3 ubiquitin ligase complex for neddylation. DCUN1D1 functions to recruit charged E2 and is involved in the release of inhibitory effects of CAND1 on cullin-RING ligase E3 comp...
TMPY-04392	RSK3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Ribosomal protein S6 kinase alpha-2, also known as 9 kDa ribosomal protein S6 kinase 2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, Ribosomal S6 kinase 3, RSK-3, RPS6KA2 and MAPKAPK1C, is a ...