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天然化合物

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カタログ番号	製品名	別名	ターゲット
T10220	LSN2839567	Abemaciclib metabolite M2	CDK
	LSN2839567 (Abemaciclib metabolite M2) is the active metabolite of Abemaciclib, a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anticancer activity.LSN2839567 inhibits CDK9.LSN2839567 inhibits cell growth and cell ...		CDK
T7537	Norgestimate		Progesterone Receptor
	Norgestimate is an acetylated progestinused in combination with ethinyl estradiol as an oral contraceptive.		Progesterone Receptor
T12412L	PDK4-IN-1 hydrochloride		Apoptosis , PDK
			Apoptosis , PDK
T3281	Delapril hydrochloride	indalapril,Alindapril Hydrochloride,Delapril Hydrochloride,CV 3317	RAAS
	Delapril hydrochloride (indalapril) is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhibit angiotensin-converting enzyme...		RAAS
T40729	D-Threonine	H-D-Thr-OH,D-Threonine	Endogenous Metabolite
	D-Threonine (H-D-Thr-OH) is one of the metabolites of Saccharomyces cerevisiae.		Endogenous Metabolite
T1690	BroMhexine IMpurity B		Others
	Bromhexine Impurity B reagent used in the preparation of Ambroxol and Bromhexine (B678600) metabolites Ambroxol EP Impurity E.		Others
T20026	WEB-1868	WEB 1868,WEB1868	Others
	WEB-1868 is one of the metabolites of nebracetam which is an agonist for human M1-muscarinic receptors.		Others
T37196	5-AAM-2-CP		AChR
	5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.		AChR
T1414	Sodium 2-mercaptoethanesulfonate	Mitexan,Uromitexan,Mesna,Mesnum,Mesnex	Others
	Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide.		Others
T22317	DRB18		transporter
	DRB18 is a highly effective pan-class inhibitor of glucose transporter proteins (GLUT). It significantly modulates energy-related metabolism in A549 cells by inducing alterations in the abundance of metabolites associate...		transporter
T19498	P-Cresyl sulfate potassium	p-Tolyl sulfate potassium salt,p-Cresol sulfate potassium,p-Methylphenyl potassium sulfate,Potassium p-tolyl sulfate	Endogenous Metabolite
	p-Cresyl sulfate potassium (p-Tolyl sulfate potassium salt) is a prototype protein-bound uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver.		Endogenous Metabolite
TD0105	Sulfobromophthalein disodium salt		Others
	Sulfobromophthalein disodium salt is an organic anion dye, it is used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of drugs and metabolites.		Others
T8483	Cysteine thiol probe	Methyl (4-bromobenzoyl)-L-cysteinate	Others
	Cysteine thiol probe (Methyl (4-bromobenzoyl)-L-cysteinate) is a chemoselective thiol probe for detection of electrophilic metabolites		Others
T37359	Myristoyl-L-carnitine chloride	L-Myristoylcarnitine chloride	Endogenous Metabolite
	Myristoyl-L-carnitine chloride (L-Myristoylcarnitine chloride) is one of the body's metabolites implicated in inherited metabolic disorders.Tetradecanoylcarnitine is a potential marker for the study of diabetes mellitus ...		Endogenous Metabolite
T9831	MKC-1	Ro-31-7453	Apoptosis , Akt , Microtubule Associated , mTOR
	MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the format...		Apoptosis , Akt , Microtubule Associated , mTOR
T4630	NSC 404988		Others
	NSC 404988 is a benzamide-based bioactive compound used in the synthesis of compounds and the preparation of drugs, and has also been used in the study of drug metabolism and the analysis of metabolites in biological sys...		Others
T2112	Fexinidazole	HOE 239	Others , Parasite
	Fexinidazole (HOE 239) is an antiparasitic agent. It has activity against Trypanosoma cruzi, Tritrichomonas foetus, Trichomonas vaginalis, Entamoeba histolytica, Trypanosoma brucei, and Leishmania donovani. The biologica...		Others , Parasite
T1229	Erdosteine	RV 144,KW-9144	NF-κB , Antibacterial , Adenosine deaminase
	Erdosteine (RV 144) is a homocysteine-derived thiol derivative with mucolytic and free radical scavenging properties. Erdosteine and its metabolites modulate mucus production and viscosity, by which facilitating mucocili...		NF-κB , Antibacterial , Adenosine deaminase
T36536	SH-42
	SH-42 is an inhibitor of 24-dehydrocholesterol reductase (DHCR24; IC50= 4.2 nM).1It increases serum levels of desmosterol , the immediate precursor of cholesterol in the Bloch pathway, in mice when administered at a dos...
T0765	Fomepizole	Antizol-Vet,4-Methylpyrazole,Antizol	P450 , CAT , AChR
	Fomepizole (4-Methylpyrazole) is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole(4-Methylpyrazole) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that cata...		P450 , CAT , AChR
T16537	Pimonidazole		Others
	Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group. It can be used for qualitative and quantitative assessment of...		Others
T36640	Xanomeline	LY-246708	AChR
	Xanomeline (LY-246708) is a functionally selective M1/M4 activator used in the study of neurological disorders such as schizophrenia and has shown promising treatment in preclinical trials. Xanomeline is well absorbed or...		AChR
T6446	Clevudine	L-FMAU,Levovir	HBV , DNA/RNA Synthesis
	Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The ...		HBV , DNA/RNA Synthesis
T16536	Pimonidazole hydrochloride
	Pimonidazole hydrochloride accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group. It can be used for qualitative and quantitative...
T1408	Capecitabine	Xeloda,Capecitibine,Capiibine,RO 09-1978	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moie...
T36696	DMBA
	7,12-Dimethylbenz[a]anthracene (DMBA) is a polycyclic aromatic hydrocarbon (PAH) that has been found in tobacco smoke and diesel exhaust and has carcinogenic activity.1,2It undergoes metabolic activation by numerous enzy...
T15498	HOKU-81	4-Hydroxytulobuterol	Others
	HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.		Others
T10956	Dansyl glutathione	DNS-glutathione	Others
	Dansyl glutathione is a capture agent used for quantitative assessment and identification of reactive metabolites.		Others
T33781	O-Demethyldeacetyldiltiazem	Deacetyl-O-demethyldiltiazem,Deacetyl-O-demethyl-D-diltiazem,Deacetyl o-desmethyl diltiazem
	O-Demethyldeacetyldiltiazem is one of the diltiazem metabolites in human plasma.
T69406	Sydnophene
	Sydnophene is an intermediate in the synthesis of metabolites of Mesocarb -- a CNS stimulant that acts as a dopamine reuptake inhibitor.
T29407	3-Hydroxydecanedioic acid
	3-hydroxydecanedioic acid can be found in ketoacidosis of urinary metabolites.
T37195	5'-hydroxy Meloxicam
	5'-hydroxy Meloxicam is one of the metabolites of meloxicam (MEL).
T31248	Deacetyl-N-monodemethyldiltiazem
	Deacetyl-N-monodemethyldiltiazem is a major metabolites of diltiazem.
T38035	Phenol-13C6	Phenol-13C6
	Phenol-13C6is a building block.1It has been used in the synthesis of13C6-labeled metabolites of (±)-asenapine . 1.Kuethe, J.T.Synthesis of stable isotope‐labeled metabolites of asenapineJ. Labelled Comp. Radiopharm.55(5)...
T32783	Lipoxin C4	15-OH-Ltc3
	Lipoxin C4 is a bioactive autacoid metabolites of arachidonic acid made by various cell types. It is categorized as a nonclassic eicosanoid and member of the specialized pro-resolving mediator (SPMs) family of polyunsatu...
T21316	Apaziquone	EO-9,NSC382459,EO9,NSC 382459,EO 9,NSC-382459
	Apaziquone has potential antineoplastic and radiosensitization activities. It is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. ...
T37361	6β-hydroxy Dexamethasone
	6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-...
T37180	Avanafil metabolite M16
	Avanafil metabolite M16 is a major inactive metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil . Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites ava...
T13291	VD3-D6	Vitamin D3-26,26,26,27,27,27-d6	Others
	VD3-D6 is the deuterated form of Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.		Others
T35037	Vanilmandelic acid, L-(+)-	Vanilmandelic acid L-form,(+)-Vanilmandelic acid
	Vanilmandelic acid, L-(+)- is a chemical intermediate in the synthesis of artificial vanilla flavorings and is an end-stage metabolite of the catecholamines, epinephrine, and norepinephrine. It is produced via intermedia...
T37181	Avanafil metabolite M4	Avanafil metabolite M4
	Avanafil metabolite M4 is a major active metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil . Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites avanaf...
T35849	17(S)-HETE
	Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.17-...
T37238	(±)19(20)-EpDPA
	EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de...
T37235	(±)16(17)-EpDPA	(±)16,17-EpDPE,(±)16,17 EDP,(±)16,17-epoxy Docosapentaenoic Acid,(±)16,17-epoxy DPA,(±)16(17)-EpDPA
	EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de...
T37708	17(R)-HETE
	Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 17...
T37234	(±)14(15)-EpETE
	EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de...
T37149	Carbamazepine 10,11-epoxide		Others
	Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine.1,2It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells e...		Others
T35727	4-methyl-2-Oxovalerate (sodium salt)
	4-methyl-2-Oxovalerate is an immediate precursor and metabolite of L-leucine. It is a precursor leading to the synthesis of 2-methylpropyl glucosinolate, via L-leucine, in plants. 4-methyl-2-Oxovalerate is one of several...
T36237	5-hydroxy Propranolol
	5-hydroxy Propranolol is a metabolite of propranolol , a β-adrenergic receptor antagonist. Propranolol is primarily metabolized in the liver, with cytochrome P450 isoform 2D6 directing ring hydroxylation and the generati...
T35495	(±)13(14)-DiHDPA
	(±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases. Epoxygenase metabolites of DHA, including (±)13(14)-DiHDPA, are reported to inhibit angiogenesis, t...

Compounds

LSN2839567

T10220

Synonym: Abemaciclib metabolite M2

Target: Progesterone Receptor

PDK4-IN-1 hydrochloride

T12412L

Synonym:

Target: Apoptosis, PDK

Delapril hydrochloride

T3281

Synonym: indalapril,Alindapril Hydrochloride,Delapril Hydrochloride,CV 3317

Target: RAAS

D-Threonine

T40729

Synonym: H-D-Thr-OH,D-Threonine

Target: Endogenous Metabolite

BroMhexine IMpurity B

Synonym: WEB 1868,WEB1868

Sodium 2-mercaptoethanesulfonate

T1414

Synonym: Mitexan,Uromitexan,Mesna,Mesnum,Mesnex

p-Cresyl sulfate potassium

T19498

Synonym: p-Tolyl sulfate potassium salt,p-Cresol sulfate potassium,p-Methylphenyl potassium sulfate,Potassium p-tolyl sulfate

Target: Endogenous Metabolite

Sulfobromophthalein disodium salt

Synonym: Methyl (4-bromobenzoyl)-L-cysteinate

Target: Others

Myristoyl-L-carnitine chloride

T37359

Synonym: L-Myristoylcarnitine chloride

Target: Endogenous Metabolite

MKC-1

T9831

Synonym: Ro-31-7453

Target: Apoptosis, Akt, Microtubule Associated, mTOR

Target: Others, Parasite

Erdosteine

T1229

Synonym: RV 144,KW-9144

Target: NF-κB, Antibacterial, Adenosine deaminase

Synonym: Antizol-Vet,4-Methylpyrazole,Antizol

Target: P450, CAT, AChR

Synonym: L-FMAU,Levovir

Target: HBV, DNA/RNA Synthesis

Pimonidazole hydrochloride

Synonym: Xeloda,Capecitibine,Capiibine,RO 09-1978

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Synonym: 4-Hydroxytulobuterol

Target: Others

Dansyl glutathione

T10956

Synonym: DNS-glutathione

Target: Others

O-Demethyldeacetyldiltiazem

T33781

Synonym: Deacetyl-O-demethyldiltiazem,Deacetyl-O-demethyl-D-diltiazem,Deacetyl o-desmethyl diltiazem

3-Hydroxydecanedioic acid

Deacetyl-N-monodemethyldiltiazem

Synonym: EO-9,NSC382459,EO9,NSC 382459,EO 9,NSC-382459

Target:

6β-hydroxy Dexamethasone

T37361

Synonym:

Target:

Avanafil metabolite M16

Synonym: Vitamin D3-26,26,26,27,27,27-d6

Target: Others

Vanilmandelic acid, L-(+)-

T35037

Synonym: Vanilmandelic acid L-form,(+)-Vanilmandelic acid

Target:

Avanafil metabolite M4

T37181

Synonym: Avanafil metabolite M4

Synonym: (±)16,17-EpDPE,(±)16,17 EDP,(±)16,17-epoxy Docosapentaenoic Acid,(±)16,17-epoxy DPA,(±)16(17)-EpDPA

Carbamazepine 10,11-epoxide

T37149

Synonym:

Target: Others

4-methyl-2-Oxovalerate (sodium salt)

T35727

Synonym:

Target:

5-hydroxy Propranolol

カタログ番号	製品名	別名	ターゲット
T2S2173	(E)-Naringenin chalcone	Isosalipurpol,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone	Others
	Naringenin chalcone (Isosalipurpol) has antiallergic activity Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. Naringenin chalcone is a potent tomato flavonoid tha...		Others
TN6088	Tricoumaroyl spermidine	N1,N5,N10-(Z)-tri-p-coumaroylspermidine,N1,N5,N10-(E)-Tri-p-coumaroylspermidine,N1,N5,N10-Tri-p-coumaroylspermidine	5-HT Receptor
	Tricoumaroyl spermidine(N1,N5,N10-(Z)-tri-p-coumaroylspermidine) was discovered as unique tea (Camellia sinensis) flower metabolites.		5-HT Receptor
T8120	N-Benzyloctadecanamide	N-Benzylstearamide	Others
	N-Benzyloctadecanamide is a distinct class of secondary metabolites in Lepidium meyenii Walp. (Maca).		Others
TN7068	Sinomenine N-oxide		Others
	Sinomenine N-oxide is one of the major metabolites of the cyclic metabolic mechanism of Sinomenine.		Others
T5226	2-(2-Methylbenzamido)acetic acid	2-Methylhippuric acid,O-Toluric acid,N-(O-Toluoyl)glycine	Others , Endogenous Metabolite
	2-(2-Methylbenzamido)acetic acid (O-Toluric acid) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. In certain cases, the measurement of these metabolites in body fluids can be used to diag...		Others , Endogenous Metabolite
TQ0024	3-Hydroxyglutaric acid		Endogenous Metabolite
	3-Hydroxyglutaric acid is one of several metabolites produced when insufficient levels of GCDH are available. It is used as a biomarker of GCDH deficiency.		Endogenous Metabolite
T7437	3-(3-Hydroxyphenyl)propionic Acid	m-Hydroxyphenylpropionic acid,3-Hydroxyhydrocinnamic acid	Others , Endogenous Metabolite
	3-(3-Hydroxyphenyl)propionic Acid (m-Hydroxyphenylpropionic acid) is one of the major metabolites of ingested caffeic acid.it inhibited osteoclastogenesis and bone osteoclastic resorptive activity.		Others , Endogenous Metabolite
T5228	Nicotinuric acid		Others , Endogenous Metabolite
	Nicotinuric acid is an acyl glycine which is normally minor metabolites of fatty acids. Acyl glycines are produced through the action of glycine N-acyltransferase.		Others , Endogenous Metabolite
T13542	α-Zearalenol		Estrogen Receptor/ERR
	α-Zearalenol is one of the major metabolites of Zearalenone. α-Zearalenol has structural analogy to estrogen, thus α-Zearalenol can bind to estrogen receptors (ERs).		Estrogen Receptor/ERR
T74862	N-Lactoyl-Phenylalanine	N-Lactoylphenylalanine	Endogenous Metabolite
	N-Lactoyl-Phenylalanine (Lac-Phe) is a peptide coupling of lactic acid and phenylalanine, one of the metabolites in acute exercise, which can be used in the study of obesity and metabolism-related diseases.		Endogenous Metabolite
TN1714	Grosvenorine	Grosvenorin	Antibacterial
	Grosvenorine (Grosvenorin) exhibits good antibacterial and antioxidant activities, with its metabolites possessing more potent activities, intestinal bacteria play an important role in the gastrointestinal metabolism of ...		Antibacterial
T5245	N-Isovaleroylglycine	Isovaleroylglycine,N-Isovalerylglycine	Others , Endogenous Metabolite
	N-Isovaleroylglycine (Isovaleroylglycine) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metaboli...		Others , Endogenous Metabolite
T16338	Norgestimate metabolite Norelgestromin	17-Deacetyl norgestimate,17-Deacylnorgestimate	Drug Metabolite
	Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive patches, where it is combined with the estrogen ethinyl es...		Drug Metabolite
T4940	3-Methylhistamine dihydrochloride		Others , Endogenous Metabolite
	N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histamine metabolite is generally less hampere...		Others , Endogenous Metabolite
T4840	3-Hydroxybenzoic acid		Others , Endogenous Metabolite
	Produced in the gut microflora as one of the three main metabolites formed from the catechin diet. Its use in the production of glycol benzoates for the application of plasticizer in adhesive formulations is increasing. ...		Others , Endogenous Metabolite
T5256	All-trans-retinal	All trans-Retinal,Retinaldehyde,Vitamin A aldehyde	Others , Endogenous Metabolite
	All-trans-retinal (Vitamin A aldehyde) is a one of the major vitamin A metabolites in the retina. All-trans-RAL is regenerated to the visual chromophore, 11-cis-retinal in physiological conditions.		Others , Endogenous Metabolite
T21977	P-Cresyl sulfate		Others
	p-Cresyl Sulfate is a major uremic toxin found in the blood of patients with chronic kidney disease (CKD), derived from the metabolites of tyrosine and phenylalanine in the liver.		Others
T3665	Tectoridin	Shekanin	Estrogen Receptor/ERR , Reductase
	Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin an...		Estrogen Receptor/ERR , Reductase
T6520	Grape Seed Extract	Grape Seed P.E.	Apoptosis , Others
	Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (BIOFLAVONOIDS and polyphenols) credited with important medicinal properties.		Apoptosis , Others
T5285	3-(Methylthio)propionic acid	3-Methylthiopropionate,4-Thiapentanoic acid,3-Methylsulfanylpropionic acid	Others , Endogenous Metabolite , Antifungal
	3-(Methylthio)propionic acid (4-Thiapentanoic acid) is one of the metabolites of methionine (especially of D-methionine). Cultures of Streptomyces lincolnensis accumulated 3-methylthioacrylic acid in amounts directly rel...		Others , Endogenous Metabolite , Antifungal
T5217	2-(2-Phenylacetamido)acetic acid	Phenaceturic acid,Phenyl-ac-Gly-OH,Phenylacetyl glycine	Others , Endogenous Metabolite
	2-(2-Phenylacetamido)acetic acid (Phenyl-ac-Gly-OH) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. The presence of phenylacetylglycine in urine has been confirmed for dogs, rats, and mic...		Others , Endogenous Metabolite
T3S1227	Aristolactam I	Aristolactam,Aristololactam I,Aristololactum	Apoptosis , Caspase
	1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF...		Apoptosis , Caspase
T5294	(S)-Leucic acid	L-LEUCIC ACID,Hydroxyisocaproic acid,(S)-(−)-2-Hydroxyisocaproic acid	Others , Endogenous Metabolite
	(S)-Leucic acid (Hydroxyisocaproic acid) is an end product of leucine metabolism in human tissues such as muscle and connective tissue. It belongs to 2-hydroxycarboxylic acid group of amino acid metabolites. (S)-Leucic a...		Others , Endogenous Metabolite
T5215	N-(3-Phenylpropionyl)glycine	Phenylpropionylglycine	Others
	N-(3-Phenylpropionyl)glycine (Phenylpropionylglycine) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors...		Others
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T3578	Pyridoxal phosphate	PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate	Reverse Transcriptase , Endogenous Metabolite
	Pyridoxal phosphate (Vitamin B6 phosphate) is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and d...		Reverse Transcriptase , Endogenous Metabolite
T38373	2-heptyl-3-hydroxy-4(1H)-Quinolone	2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal	Others
	2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB ...		Others
T4838	(S)-Malic acid	L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid	Others , Endogenous Metabolite
	(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a tart-tasting organic dicarboxylic acid that plays a role in many sour or tart foods. Apples contain malic acid, which contributes to the sourness of a green apple. Malic a...		Others , Endogenous Metabolite
T14031	3-Hydroxyhippuric acid		Others
	3-Hydroxyhippuric acid is an acyl glycine, which are normally minor metabolites of fatty acids.		Others
TN5600	Paniculoside III
	Paniculoside III is a natural product from the metabolites of the algicolous fungus Stevia paniculata.
TN5376	Axinysone B	(-)-Axinysone B
	Axinysone B is a natiral product from the metabolites of the mushroom Anthracophyllum sp. BCC18695.
TN2679	2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one		Others
	2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one is a natural product from the metabolites of Hypericum revolutum ssp.		Others
TN5788	Phyllostine
	Phyllostine appears to be their more immediate precursor, since PCMB-treated extracts of J2 converted Phyllostine but not isoepoxydon to these new metabolites.
T9456	4-Methoxy 17β-Estradiol		Others
	4-Methoxy-17-estradiol is one of the estrogen metabolites and a methylation metabolite of 4-hydroxyestradiol.		Others
TN5278	Zederone		NADPH-oxidase , P450 , TNF , Nrf2 , Antifection
	Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads to the formation of biological reactive metabolites and that...		NADPH-oxidase , P450 , TNF , Nrf2 , Antifection
TN3878	Dl-Aloesol		Others
	dl-Aloesol is a natural product from the secondary metabolites of endophytic fungus HCCB06030.		Others
TN2801	20-Hydroxyaflavinine		Others
	20-Hydroxyaflavinine is a natural product from the metabolites of the ascomycete fungus Tricladium sp.		Others
TN3890	Drechslerine A		Others
	Drechslerine A is a natural product from the metabolites of the algicolous fungus Drechslera dematioidea.		Others
T73607	UDP-xylose
	UDP-xylose, a natural product isolated from Cryptococcus laurentii (NRRL Y-1401), serves as a sugar donor in the synthesis of glycoproteins, polysaccharides, various metabolites, and oligosaccharides across plants, verte...
T83138	Aloinoside A
	Aloinoside A, an aloin isolated from Astragalus membranaceus, is the enantiomer of Aloinoside B and is a biomarker used in metabolic research. Its metabolic products by rat intestinal bacteria include aloin, isoaloin and...
T75621	Secalonic acid D
	Secalonic acid D, a toxic compound effective against tumor cells, is derived from the metabolites of Aspergillus aculeatus. It operates by activating GSK3-β and degrading β-catenin, consequently down-regulating c-Myc exp...
T36438	Sporogen-AO 1
	Sporogen-AO 1 is a fungal metabolite originally isolated fromA. oryzaethat has diverse biological activities.1,2,3,4,5It inhibits HIV-1 Tat transactivation in a cell-based assay with an IC50value of 15.8 μM.4Sporogen-AO ...
T35761	Carviolin
	Carviolin is an anthraquinone fungal metabolite that has been found inZ. longicaudatawith immunosuppressive and antitrypanosomal activities.1,2It inhibits LPS- or concanavalin A-induced proliferation of mouse splenocytes...
T37609	(rel)-Asperparaline A
	Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) la...
T36000	3-Hydroxyterphenyllin
	3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,...
T35750	Trypacidin
	Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, re...
T35779	Oosporein
	Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectiv...

天然物製品

(E)-Naringenin chalcone

T2S2173

Synonym: Isosalipurpol,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone

Target: Others

tricoumaroyl spermidine

TN6088

Synonym: N1,N5,N10-(Z)-tri-p-coumaroylspermidine,N1,N5,N10-(E)-Tri-p-coumaroylspermidine,N1,N5,N10-Tri-p-coumaroylspermidine

Target: 5-HT Receptor

N-Benzyloctadecanamide

T8120

Synonym: N-Benzylstearamide

2-(2-Methylbenzamido)acetic acid

T5226

Synonym: 2-Methylhippuric acid,O-Toluric acid,N-(O-Toluoyl)glycine

Target: Others, Endogenous Metabolite

3-Hydroxyglutaric acid

TQ0024

Synonym:

Target: Endogenous Metabolite

3-(3-Hydroxyphenyl)propionic Acid

T7437

Synonym: m-Hydroxyphenylpropionic acid,3-Hydroxyhydrocinnamic acid

Target: Others, Endogenous Metabolite

Nicotinuric acid

T5228

Synonym:

Target: Others, Endogenous Metabolite

α-Zearalenol

T13542

Synonym:

Target: Estrogen Receptor/ERR

N-Lactoyl-Phenylalanine

T74862

Synonym: N-Lactoylphenylalanine

Target: Endogenous Metabolite

Grosvenorine

TN1714

Synonym: Grosvenorin

Target: Antibacterial

N-Isovaleroylglycine

T5245

Synonym: Isovaleroylglycine,N-Isovalerylglycine

Target: Others, Endogenous Metabolite

Norgestimate metabolite Norelgestromin

T16338

Synonym: 17-Deacetyl norgestimate,17-Deacylnorgestimate

Target: Drug Metabolite

3-Methylhistamine dihydrochloride

T4940

Synonym:

Target: Others, Endogenous Metabolite

3-Hydroxybenzoic acid

T4840

Synonym:

Target: Others, Endogenous Metabolite

All-trans-retinal

T5256

Synonym: All trans-Retinal,Retinaldehyde,Vitamin A aldehyde

Target: Others, Endogenous Metabolite

Target: Estrogen Receptor/ERR, Reductase

Grape Seed Extract

T6520

Synonym: Grape Seed P.E.

Target: Apoptosis, Others

3-(Methylthio)propionic acid

T5285

Synonym: 3-Methylthiopropionate,4-Thiapentanoic acid,3-Methylsulfanylpropionic acid

Target: Others, Endogenous Metabolite, Antifungal

2-(2-Phenylacetamido)acetic acid

T5217

Synonym: Phenaceturic acid,Phenyl-ac-Gly-OH,Phenylacetyl glycine

Target: Others, Endogenous Metabolite

Aristolactam I

T3S1227

Synonym: Aristolactam,Aristololactam I,Aristololactum

Target: Apoptosis, Caspase

(S)-Leucic acid

T5294

Synonym: L-LEUCIC ACID,Hydroxyisocaproic acid,(S)-(−)-2-Hydroxyisocaproic acid

Target: Others, Endogenous Metabolite

N-(3-Phenylpropionyl)glycine

T5215

Synonym: Phenylpropionylglycine

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Pyridoxal phosphate

T3578

Synonym: PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate

Target: Reverse Transcriptase, Endogenous Metabolite

2-heptyl-3-hydroxy-4(1H)-Quinolone

T38373

Synonym: 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal

Target: Others

(S)-Malic acid

T4838

Synonym: L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid

Target: Others, Endogenous Metabolite

3-Hydroxyhippuric acid

Synonym: (-)-Axinysone B

Target:

2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one

4-Methoxy 17β-Estradiol

Target: NADPH-oxidase, P450, TNF, Nrf2, Antifection

(rel)-Asperparaline A

T37609

Synonym:

Target:

3-Hydroxyterphenyllin

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-00740	Transaldolase B Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Transaldolase B Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag....
TMPH-02102	PON1 Protein, Human, Recombinant (GST)	Human	E. coli
	Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediate...
TMPH-02903	PON1 Protein, Mouse, Recombinant	Mouse	E. coli
	Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediate...
TMPH-00091	UGT71C1 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His)	Arabidopsis thaliana	P. pastoris (Yeast)
	Possesses quercetin 7-O-glucosyltransferase and 3'-O-glucosyltransferase activities in vitro. Also active in vitro on benzoates and benzoate derivatives. Glucosylates other secondary metabolites in vitro like trans-resve...
TMPH-00090	UGT71C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His)	Arabidopsis thaliana	E. coli
	Possesses quercetin 7-O-glucosyltransferase and 3'-O-glucosyltransferase activities in vitro. Also active in vitro on benzoates and benzoate derivatives. Glucosylates other secondary metabolites in vitro like trans-resve...
TMPH-02141	CYP21A2 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-d...
TMPH-01021	BTN3A1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells ...
TMPJ-00105	SOD2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic super...
TMPH-01020	BTN3A1 Protein, Human, Recombinant (Yeast, His)	Human	P. pastoris (Yeast)
	Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells ...
TMPH-02140	CYP21A2 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-d...
TMPH-01597	KYAT1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the thre...
TMPH-01388	GCKR Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a me...
TMPH-01050	CPT2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential ...
TMPH-01387	GCKR Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a me...
TMPH-01303	HSD17B11 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate stero...
TMPJ-00962	AKR1C3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate...
TMPJ-00759	VDB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. D...
TMPY-03985	Adenosine Deaminase Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Adenosine Desaminase (ADA) deficiency, is a purine metabolic disorder that cause severe combined immunodeficiency (SCID) due to the accumulation of toxic metabolites that primarily affects development, differentiation a...
TMPY-03849	NUDT5 Protein, Human, Recombinant (His)	Human	E. coli
	NUDT5 (Nudix Hydrolase 5) is a Protein Coding gene. This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphos...
TMPY-02452	CMBL Protein, Human, Recombinant (His)	Human	E. coli
	Carboxymethylenebutenolidase (CMBL), also known as 4-carboxymethylenebut-2-en-4-olide lactonohydrolase, maleylacetate enol- lactonase, dienelactone hydrolase, and carboxymethylene butenolide hydrolase, is a hydrolase spe...
TMPY-01140	ACOT13/THEM2 Protein, Human, Recombinant (His)	Human	E. coli
	The metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription. Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty ...
TMPH-02139	CYP17A1 Protein, Human, Recombinant (GST)	Human	E. coli
	A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen sy...
TMPY-01617	SULT1B1 Protein, Human, Recombinant (His)	Human	E. coli
	Sulfotransferase family cytosolic 1B member 1, also known as Sulfotransferase 1B1, Sulfotransferase 1B2, Thyroid hormone sulfotransferase, SULT1B1 and ST1B2, is a cytoplasm protein that belongs to the sulfotransferase 1 ...
TMPY-01616	SULT2B1 Protein, Human, Recombinant (His)	Human	E. coli
	Sulfotransferase family cytosolic 2B member 1, also known as Sulfotransferase 2B1, ST2B1, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, SULT2B1 and HSST2, is a cytoplasm protein that belongs to the sulfotr...
TMPH-02524	Arginase-1/ARG1 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ...

Transaldolase B Protein, E. coli, Recombinant (His & Myc)

TMPH-00740

Species: E. coli

Expression System: E. coli

PON1 Protein, Human, Recombinant (GST)

TMPH-02102

Species: Human

Expression System: E. coli

PON1 Protein, Mouse, Recombinant

TMPH-02903

Species: Mouse

Expression System: E. coli

UGT71C1 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His)

TMPH-00091

Species: Arabidopsis thaliana

Expression System: P. pastoris (Yeast)

UGT71C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His)

TMPH-00090

Species: Arabidopsis thaliana

Expression System: E. coli

CYP21A2 Protein, Human, Recombinant (His)

TMPH-02141

Species: Human

Expression System: P. pastoris (Yeast)

BTN3A1 Protein, Human, Recombinant (E. coli, His)

TMPH-01021

Species: Human

Expression System: E. coli

SOD2 Protein, Human, Recombinant (His)

TMPJ-00105

Species: Human

Expression System: HEK293 Cells

BTN3A1 Protein, Human, Recombinant (Yeast, His)

TMPH-01020

Species: Human

Expression System: P. pastoris (Yeast)

CYP21A2 Protein, Human, Recombinant (E. coli, His)

TMPH-02140

Species: Human

Expression System: E. coli

KYAT1 Protein, Human, Recombinant (His & SUMO)

TMPH-01597

Species: Human

Expression System: E. coli

GCKR Protein, Human, Recombinant (His & SUMO)

TMPH-01388

Species: Human

Expression System: E. coli

CPT2 Protein, Human, Recombinant (His & Myc)

TMPH-01050

Species: Human

Expression System: E. coli

GCKR Protein, Human, Recombinant (His)

TMPH-01387

Species: Human

Expression System: P. pastoris (Yeast)

HSD17B11 Protein, Human, Recombinant (His & Myc)

TMPH-01303

Species: Human

Expression System: E. coli

AKR1C3 Protein, Human, Recombinant (His)

TMPJ-00962

Species: Human

Expression System: HEK293 Cells

VDB Protein, Human, Recombinant (His)

TMPJ-00759

Species: Human

Expression System: HEK293 Cells

Adenosine Deaminase Protein, Human, Recombinant (His)

TMPY-03985

Species: Human

Expression System: Baculovirus Insect Cells

NUDT5 Protein, Human, Recombinant (His)

TMPY-03849

Species: Human

Expression System: E. coli

CMBL Protein, Human, Recombinant (His)

TMPY-02452

Species: Human

Expression System: E. coli

ACOT13/THEM2 Protein, Human, Recombinant (His)

TMPY-01140

Species: Human

Expression System: E. coli

CYP17A1 Protein, Human, Recombinant (GST)

TMPH-02139

Species: Human

Expression System: E. coli

SULT1B1 Protein, Human, Recombinant (His)

TMPY-01617

Species: Human

Expression System: E. coli

SULT2B1 Protein, Human, Recombinant (His)

TMPY-01616

Species: Human

Expression System: E. coli

Arginase-1/ARG1 Protein, Mouse, Recombinant (His)

TMPH-02524

Species: Mouse

Expression System: P. pastoris (Yeast)

カタログ番号	製品名
L2570	Human Metabolite Library	4454 compounds
	A unique collection of 4454 human metabolites for high-throughput, high-content screening.
L2530	Mouse Metabolite Compound Library	218 compounds
	A unique collection of 218 mouse metabolites, which can be used for HTS and HCS;
L2500	Human Endogenous Metabolite Library	499 compounds
	A collection of 499 selected human endogenous metabolites for high throughput and high content screening.
L5800	Drug Metabolite/Impurity Library	197 compounds
	A unique collection of 197 drug isomers/metabolites for high throughput screening (HTS) and high content screening (HCS);
L2540	Gut Microbial Metabolite Library	607 compounds
	A unique collection of 607 gut microbial metabolites which can be used for HTS and HCS;
L2501	Human Endogenous Metabolite Compound Library Plus	1283 compounds

L6001	Mini Fungal Metabolite Natural Product Screening Library	Inquiry

L2510	Lipid Metabolism Compound Library	492 compounds
	A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
L6120	Flavonoid Natural Product Library	514 compounds
	A unique collection of 514 flavonoids can be used for high throughput and high content screening；