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T22231 |
Adenosine Dialdehyde (ADOX)
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Periodate-oxidized adenosine,Adenosine, periodate oxidized,Adenox,Adenosinedialdehyde |
Others
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Adenosine Dialdehyde (Periodate-oxidized adenosine) is a purine nucleoside analogue. Adenosine Dialdehyde is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent... |
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T36173 |
L-Glutathione, oxidized (sodium salt)
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Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized fo... |
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T78639 |
Oxidized ATP trisodium salt
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oATP trisodium salt |
P2X Receptor
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Oxidized ATP trisodium salt (oATP) is a broad-spectrum inhibitor of P2 receptors, irreversibly antagonizing P2X7R activation and inhibiting c-reactive protein (CRP)-induced NLRP3 inflammasome activation. It is utilized i... |
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T8734 |
Choline
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Others
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Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins |
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T20062 |
Thiamine disulfide
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TDS,Daiomin,Algoneurina |
HIV Protease
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Endogenous Metabolite
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Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication. Thiamine also acts as a cofactor for many centrally metabolizing... |
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T69111 |
2',3'-Dialdehyde ATP
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2',3'-Dialdehyde ATP is a derivative of, and the oxidized form of, ATP. It has been found to be a specific, irreversible inhibitor of component A3 of the methylreductase system which plays a role in processing amino acid... |
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T7871 |
Calcium D-saccharate tetrahydrate
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D-Glucaric acid calcium salt,Calcium D-saccharate tetrahydrate,D-Saccharic acid calcium salt |
Others
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Calcium D-saccharate tetrahydrate (Calcium D-saccharate tetrahydrate) is an oxidized non-cyclic hexose sugar. It may inhibit carcinogenesis and proliferation of cancer cells. |
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T2069L |
TH287 hydrochloride
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DNA/RNA Synthesis
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MTH1
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TH287 is a selective MTH1 inhibitor(IC50 : 0.8 nM). It causees incorporation of oxidized dNTPs in cancer cells, leading to DNA damage, cytotoxicity and therapeutic responses in patient-derived mouse xenografts. |
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T19294 |
Docosahexaenoic Acid methyl ester
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Methyl docosahexaenoate,all cis-DHA methyl ester |
Others
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Docosahexaenoic Acid methyl ester (all cis-DHA methyl ester) is a methylated docosahexaenoic acid analog that can be inserted into membrane phospholipids without being oxidized or hydrolyzed. |
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T19210 |
Biotin LC hydrazide
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Biotinamidocaproyl hydrazide,Biotin Aminocaproyl Hydrazide,(+)-Biotinamidohexanoic Acid hydrazide,BACH |
Others
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Biotin LC hydrazide (BACH) is a modification reagent of long-chain protein. Biotin LC hydrazide transforms periodate-oxidized glycoproteins and can be used to target glycoproteins and glycans. |
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T83633 |
1-N-Methyl-4-mercaptohistidine disulfide
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Others
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1-N-Methyl-4-mercaptohistidine disulfide is a potential Duchenne chloroplast coupling factor 1 redox regulator, an oxidized form of ochratoxin A, that inhibits light-triggered CF1 ATPase activity. |
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T29099L |
VB 201
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CI-201 |
TLR
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VB 201 is an oxidized phospholipid small molecule with anti-inflammatory activity that inhibits CD14 and Toll-like receptor 2-dependent innate cell activation and limits atherosclerosis, and can be used to study atherosc... |
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T75342 |
MitoSOX Red
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Reactive Oxygen Species
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Mitochondrial Metabolism
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Autophagy
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MitoSOX Red is a novel fluorescent probe that is specific and cell membrane-permeable and targets mitochondria in living cells.MitoSOX Red is oxidized by superoxide upon entry into the mitochondria and is not oxidized by... |
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T35941 |
DC-Chol hydrochloride
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Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride,DC-Chol (hydrochloride),DC-Cholesterol hydrochloride,Cholesteryl 3β-N-(dimethylaminoethyl)carbamate |
Beta Amyloid
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DC-Chol hydrochloride(DC-Cholesterol hydrochloride) inhibited the formation of Aβ40 fibrils under appropriate experimental conditions and significantly inhibited amyloid formation from oxidized hCT in a dose-dependent ma... |
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T20094 |
Adrenochrome
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Adraxone |
Antioxidant
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Adrenochrome (Adraxone) is a cytotoxic molecule that can be used to kill bacteria. Adrenochrome is an oxidized product of Epinephrine. Adrenochrome is a coronary systolic compound that acts on rat hearts and is associate... |
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TP2488 |
Palmitoyl Tripeptide-38 Acetate
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Palmitoyl Tripeptide-38 Acetate(1447824-23-8 Free base) |
Others
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Palmitoyl Tripeptide-38 Acetate (Palmitoyl Tripeptide-38 Acetate (1447824-23-8 Free base)) , consisting of three amino acids, is a di-oxidized lipopeptide. The peptide was inspired by a tripeptide that occurs naturally i... |
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T77577 |
SLU-PP-332
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Estrogen/progestogen Receptor
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SLU-PP-332 is a pan-estrogen receptor-related receptor (ERR) agonist with high affinity for ERRα, ERRβ, and ERRγ with EC50 values of 98, 230, and 430 nM, respectively.SLUPP-332 enhances mitochondrial function and cellula... |
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T68217 |
Diazoxon
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Diazoxon is the oxidized form of Diazinon -- an organophosphate insecticide. Diazoxon is shown to be a more potent acetylcholinesterase (AChE) inhibitor. |
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T36002 |
4-hydroxy Hexenal
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4-HHE,4-hydroxy Hexenal |
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4-hydroxy Hexenal is a lipid peroxidation product derived from oxidized ω-3 fatty acids such as DHA. [1][2] |
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T37875 |
Fenbendazole sulfone
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Fenbendazole sulfone is a minor metabolite of the anthelmintic fenbendazole . Fenbendazole undergoes oxidation to form oxfendazole, which is further oxidized to form fenbendazole sulfone. |
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T35956 |
PAz-PC
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Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were isolated and purified from oxLDL and identified as phosphatid... |
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TNU0199 |
8-Hydroxyadenosine
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Nucleoside Derivatives - 8-Modified purine nucleosides; Drugs and Inhibitors; Anticancer antibiotics; oxidized nucleic acid adduct; precursor of phosmidosine (P-prodrug) |
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T36066 |
NADP+ (sodium salt hydrate)
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NADP+ is the oxidized form of the electron donor nicotinamide adenine dinucleotide phosphate . It serves as a cofactor in various biological reactions. In addition, the balance between these reduced and oxidized forms pl... |
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T36727 |
9(S)-HODE
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9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals.[1],[2] It has been detected in atherosclerotic plaques, as an esterified component of membrane phospholipids and in oxidized LDL pa... |
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T33490 |
M-PEG12-aldehyde
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m-PEG12-aldehyde is a PEG derivative containing an aldehyde group. Aldehyde is reactive to hydrazide and aminooxy groups which are commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized ca... |
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T36171 |
KDdiA-PC
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Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as ... |
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T38312 |
L-Cysteine-glutathione disulfide
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L-Cysteine-glutathione disulfide, a glutathione derivative endogenous to mammalian cells, is comprised of the oxidized form of free glutathione tripeptide linked via a disulfide bond to L-cysteine. It has been shown to p... |
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T35959 |
PGPC
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1-Palmitoyl-2-glutaryl phosphatidylcholine |
Others
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PGPC (1-Palmitoyl-2-glutaryl phosphatidylcholine) is an oxidized phospholipid and activates peroxisome proliferator-activated receptor in a concentration-dependent manner. |
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T36172 |
KOdiA-PC
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Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as ... |
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T20014 |
Patent Blue V calcium salt
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Acid blue 3,L-Blau 3,Food Blue 3,Blue ZN 3,NSC 5010,C.I. 42051 |
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Acid blue is a dark bluish synthetic triphenylmethane dye. It used as a food coloring. The color of the dye is pH-dependent. The structure is also redox-sensitive, changing from a reduced yellow form to an oxidized red f... |
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T35846 |
13(R)-HODE cholesteryl ester
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13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid ... |
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T35843 |
9(R)-HODE cholesteryl ester
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9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid p... |
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T35853 |
9(S)-HODE cholesteryl ester
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9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid p... |
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T19264 |
D-Methionine sulfoxide hydrochloride
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D-Methionine sulfoxide hydrochloride (21056-56-4 free base) |
Others
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D-methionine sulfoxide hydrochloride is the D-isomer of methionine sulfoxide hydrochloride. Methionine sulfoxide is the oxidation product of methionine. Methionine is a restrictive amino acid in milk or legume proteins a... |
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T35580 |
POV-PC
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Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as ... |
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T36559 |
(±)9-HODE
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(±)9-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. Approximately equal proportions of both isomers are found in mitochondrial and plasma membranes of ... |
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T36415 |
N-Nitroso-N-methyl-4-Aminobutyric Acid
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N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) is a tobacco-specific nitrosamine carcinogen.1It is oxidized to the reactive metabolite methyl-2-oxopropylnitrosamine (MOPN) in isolated rat liver mitochondria.2NMBA induces ... |
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T35620 |
Ethoxyquin Dimer
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Ethoxyquin dimer is an antioxidant and metabolite of ethoxyquin .1 It prevents oxidation of polyunsaturated fatty acids in fish meal and fish oil. Dietary administration of ethoxyquin dimer (0.1, 0.3, and 0.5% w/w) induc... |
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T37301 |
PCTR2
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Protein conjugates in tissue regeneration 2 (PCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutath... |
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T83422 |
1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine
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1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine, a glycerophosphorylcholine derivative, comprises glycerol phosphate, choline, and palmitic acid and accumulates at oxidative stress sites in vivo. It potentially acts a... |
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T38099 |
APF
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APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase... |
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T36180 |
Azelaoyl PAF
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Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ. One of these substances was recently isolated and pur... |
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T35976 |
6-Formylpterin
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Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (H2O2), as it oxidizes specific substrates in the presence of water and oxygen. 6-Formylpterin is an oxidized pterin produced by photol... |
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T76395 |
(Met(O)35)-Amyloid β-Protein (1-42)
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(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that of Aβ40. This compound is utilized in Alzheimer’s disease (AD) re... |
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T74771 |
Diaporthein B
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Diaporthein B, a highly oxidized pimarane diterpene, demonstrates significant activity against M. tuberculosis with a MIC of 3.1 μg/mL and exhibits IC50 values ranging from 1.5-3 μM/L against HCT 116 and LoVo colon cance... |
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T37302 |
PCTR3
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Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutath... |
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T36001 |
4-hydroperoxy 2-Nonenal
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4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits var... |
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T80056 |
Glutathione Peroxidase
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GSH-Px,EC 1.11.1.9 |
Glutathione Peroxidase
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Glutathione Peroxidase (GSH-Px; EC 1.11.1.9), a member of the peroxidase family, catalyzes the oxidation of reduced glutathione (GSH) to oxidized glutathione (GSSG) by forming a disulfide bridge, concurrently reducing hy... |
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T75537 |
N-Acetyldopamine dimer-2
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N-Acetyldopamine dimer-2 (compound 2), an N-acetyldopamine dimer derived from the yellow powder of Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties. It notably inhibits oxidation of oxidized lo... |
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T37533 |
DOPAL
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DOPAL is an aldehyde product of the oxidative deamination of dopamine by monoamine oxidase.[1] It can be further oxidized to 3,4-dihydroxyphenylacetic acid (DOPAC) by aldehyde dehydrogenase (ALDH) and, to a lesser extent... |
