| TMPJ-00242
|
PARVA Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with i... |
| TMPH-01029
|
CAPN1 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His... |
| TMPY-00117
|
FGF-16 Protein, Human, Cynomolgus, Recombinant
|
Human,Cynomolgus |
Baculovirus Insect Cells |
|
Fibroblast growth factor 16 (FGF16) is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the ME... |
| TMPH-01031
|
CAPN2 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cle... |
| TMPY-02869
|
MMP-12 Protein, Human, Recombinant (catalytic domain)
|
Human |
E. coli |
|
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... |
| TMPJ-00662
|
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
|
Human |
E. coli |
|
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL i... |
| TMPH-02580
|
CHRAC1 Protein, Mouse, Recombinant (His & Myc)
|
Mouse |
E. coli |
|
Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1. Does not enhance nucleosome sl... |
| TMPH-02807
|
NPTXR Protein, Mouse, Recombinant (His & Myc)
|
Mouse |
Baculovirus Insect Cells |
|
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. |
| TMPH-02808
|
NPTX1 Protein, Mouse, Recombinant (His)
|
Mouse |
E. coli |
|
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. |
| TMPH-01228
|
DPYSL3 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. |
| TMPJ-00447
|
MMP-3 Protein, Human, Recombinant (His)
|
Human |
HEK293 Cells |
|
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue rem... |
| TMPH-01227
|
DPYSL2 Protein, Human, Recombinant (His)
|
Human |
P. pastoris (Yeast) |
|
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the... |
| TMPH-02557
|
CAPN1 Protein, Mouse, Recombinant (His)
|
Mouse |
E. coli |
|
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-388' and 'His... |
| TMPH-02217
|
SMARCA4 Protein, Human, Recombinant (His)
|
Human |
P. pastoris (Yeast) |
|
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic acti... |
| TMPH-03262
|
Cathepsin K Protein, Rat, Recombinant (His)
|
Rat |
E. coli |
|
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in... |
| TMPK-01232
|
PLXNA1 Protein, Human, Recombinant (His)
|
Human |
HEK293 Cells |
|
PLXNA1 (Plexin A1) is a member of plexin family that are the receptors of semaphorins. It is involved in cell migration and neuronal repulsion by affecting cytoskeletal remodeling. PLXNA1 can bind class 6 semaphorins and... |
| TMPH-01879
|
PARP11 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis. PARP11 Protein, Human, Recombinant (His) is exp... |
| TMPH-01633
|
MMP-12 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are prefer... |
| TMPK-01334
|
EMMPRIN/CD147 Protein, Canine, Recombinant (His)
|
Canine |
HEK293 Cells |
|
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiolo... |
| TMPH-01297
|
DDR1 Protein, Human, Recombinant (aa 21-417, His)
|
Human |
HEK293 Cells |
|
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival ... |
| TMPH-01665
|
TIMP3 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to ac... |
| TMPJ-00675
|
ZNHIT1 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
ZNHIT1 belongs to the ZNHIT1 family and contains one HIT-type zinc finger. It can be phosphorylated on Thr by MAPK11 or MAPK14. ZNHIT1 is a component of the chromatin-remodeling SRCAP complex, which is composed of at lea... |
| TMPJ-00362
|
MMP-2 Protein, Human, Recombinant (His)
|
Human |
HEK293 Cells |
|
72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metallo... |
| TMPH-00703
|
Pal Protein, E. coli, Recombinant (His & Myc)
|
E. coli |
E. coli |
|
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. The Tol-Pal system is also required for polar localization of ... |
| TMPH-01690
|
TIM14 Protein, Human, Recombinant (GST)
|
Human |
E. coli |
|
Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling. May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins... |
| TMPY-02689
|
MMP-3 Protein, Human, Recombinant
|
Human |
E. coli |
|
Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular... |
| TMPH-01477
|
HIST1H1D Protein, Human, Recombinant (His & MBP)
|
Human |
E. coli |
|
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structur... |
| TMPH-01874
|
Plexin-A4 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex c... |
| TMPH-01226
|
CRMP1 Protein, Human, Recombinant
|
Human |
E. coli |
|
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F... |
| TMPJ-00942
|
MMP-12 Protein, Mouse, Recombinant (His)
|
Mouse |
HEK293 Cells |
|
Matrix metalloproteinase-12（MMP12） is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic ac... |
| TMPY-04420
|
TLK1 Protein, Human, Recombinant (His & GST)
|
Human |
Baculovirus Insect Cells |
|
Tousled-like kinase 1 (or protein kinase ubiquitous, PKU-beta/TLK1) is a serine/threonine protein kinase that is implicated in chromatin remodeling, DNA replication and mitosis. TLK1 has a function important for proper c... |
| TMPH-01091
|
CHD1L Protein, Human, Recombinant (His & SUMO)
|
Human |
E. coli |
|
DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catal... |
| TMPH-01090
|
CBX8 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex... |
| TMPH-02711
|
HIST1H2BM Protein, Mouse, Recombinant (His)
|
Mouse |
E. coli |
|
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription... |
| TMPK-01286
|
MMP-8 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus |
HEK293 Cells |
|
Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance o... |
| TMPH-01061
|
Cathepsin K Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in... |
| TMPK-00359
|
Endoglin/CD105 Protein, Human, Recombinant (His & Avi)
|
Human |
HEK293 Cells |
|
Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis... |
| TMPJ-00986
|
CTCF Protein, Human, Recombinant
|
Human |
E. coli |
|
Transcriptional Repressor CTCF (CTCF) belongs to the CTCF Zinc-Finger Protein family. CTCF contains twelve C2H2-type zinc fingers and interacts with CHD8. CTCF is widely expressed in many tissues, and it is absent in pri... |
| TMPY-04559
|
CDC42BPB Protein, Human, Recombinant (His & GST)
|
Human |
Baculovirus Insect Cells |
|
CDC42BPB is a member of the serine / threonine protein kinase family that contains a Cdc42 / Rsc-binding p21 binding domain similar to that of PAK kinase. The kinase domain of this protein is related to the myotonic dyst... |
| TMPJ-00349
|
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
|
Human |
HEK293 Cells |
|
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANK... |
| TMPJ-01163
|
CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)
|
Human |
HEK293 Cells |
|
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein d... |
| TMPY-03498
|
ING4 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
ING4 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. ING4 contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling... |
| TMPJ-01040
|
MAX Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Myc-Associated Factor X (MAX) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It contains 1 basic helix-loop-helix (bHLH) domain. It is found in the brain, heart, and lun... |
| TMPJ-01130
|
NPTX1 Protein, Human, Recombinant (His)
|
Human |
HEK293 Cells |
|
Neuronal Pentraxin (NPTX1, NP1) is a secreted glycoprotein within the Pentraxin family. NPTX1 is co‑expressed and forms heteromultimers with the related secreted protein, NPTX2/NARP, NPTXR (Neuronal Pentraxin Receptor) a... |
| TMPH-03266
|
CHI3L1 Protein, Rat, Recombinant (His)
|
Rat |
E. coli |
|
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a rol... |
| TMPY-02965
|
MMP-19 Protein, Human, Recombinant
|
Human |
E. coli |
|
MMP19, also known as RASI-1, is a member of the peptidase M1A family. It contains 4 hemopexin-like domains and is expressed in the mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate... |
| TMPY-02376
|
BNIP3L Protein, Human, Recombinant
|
Human |
E. coli |
|
The deletion of BNIP3L results in retention of mitochondria during lens fiber cell remodeling, and that deletion of BNIP3L also results in the retention of endoplasmic reticulum and Golgi apparatus. BNIP3L localizes to t... |
| TMPY-02888
|
MAX Protein, Human, Recombinant (His & GST)
|
Human |
Baculovirus Insect Cells |
|
MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to the MAX family. It is highly expressed in the brain, heart, and lung while lower levels are seen in the liver, kidney, and skeletal m... |
| TMPH-02594
|
MMP-13 Protein, Mouse, Recombinant (His)
|
Mouse |
E. coli |
|
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the hig... |
| TMPY-02402
|
WTAP Protein, Human, Recombinant (GST)
|
Human |
E. coli |
|
Wilms' tumor 1-associating protein (WTAP) was previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. WT1 was originally identif... |
