検索結果

Search Results for " triterpenoid "

ターゲット

阻害剤

天然化合物

カタログ番号	製品名	別名	ターゲット
T124663	Sericoside		Immunology/Inflammation related
	Sericoside, a triterpenoid compound, is obtained from Terminalia and exhibits potent anti-inflammatory properties. Additionally, sericoside displays robust lipolytic activity, thereby aiding in the reduction of skin wrin...		Immunology/Inflammation related
T6919	Omaveloxolone	RTA-408	Apoptosis , Others , Nrf2 , STING
	Omaveloxolone (RTA-408) (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.		Apoptosis , Others , Nrf2 , STING
T6165	Bardoxolone Methyl	RTA 402,CDDO Methyl ester,TP-155,NSC 713200	Apoptosis , IκB/IKK , Ferroptosis , Nrf2 , Autophagy
	Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-tumor and anti-inflammatory activities.		Apoptosis , IκB/IKK , Ferroptosis , Nrf2 , Autophagy
T13604	CDDO-dhTFEA		Others , NF-κB , Nrf2
	CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expressi...		Others , NF-κB , Nrf2
T34516	Sapelin B	NSC 270047,NSC270047,NSC-270047
	Sapelin B is a triterpenoid.
T33627	Nematocyphol
	Nematocyphol is a triterpenoid from Euphorbia nematocypha hand-mazz.
T32044	Hancolupenol
	Hancolupenol is a novel triterpenoid compound derived from Cyanchum hancockianum.
T32565	Lantaiursolic acid
	Lantaiursolic acid is a triterpenoid extracted from the roots of Lantana camara.
T32203	Isobauerenol	(+)-Isobauerenol
	Isobauerenol is a triterpenoid compound isolated from sterile stems.
T32140	Iguesterin	Isoiguesterin
	Iguesterinn is a novel quinone triterpenoid from Catha Cassinoides with strong cell inhibitory activity.
TP2436	Saniculoside R 1	Saniculoside R-1
	Saniculoside R 1 is a new triterpenoid saponin from Sanicula europaea.
TP2437	Sarasinoside A1	Sarasinoside-A1
	Sarasinoside A1 is a triterpenoid saponin that reverses mesenchymal tumor transformation.
T34437	Rubiatriol
	Rubiatriol is a triterpenoid isolated from the root of Rubia cordifolia L.
T20613	Inotodiol
	Inotodiol is an included triterpenoid with a significant effect of anti-tumor.
T34574	Schisandronic acid	Schizandronic acid,Ganwuweizic acid
	Schisandronic acid is a triterpenoid acid isolated from the stems of Schisandra propinqua.
T33335	Methyl adenophorate
	Methyl adenophorate is a triterpenoid of Adenophora triphylla var. japonica roots.
T32325	Justicisaponin I
	Justicisaponin I is a type of triterpenoid saponin from Justicia simplex D. Don. (Acanthaceae).
T26056	Regelinol
	Regelinol is a new antitumor ursene-type triterpenoid isolated from Tripterygium regelii.
T32566	Lantanolic acid
	Lantanolic acid is a pentacyclic triterpenoid from the leaves of Lantana montevidensis.
TP2439	Sarasinoside C1	Sarasinoside-C1
	Sarasinoside C1 is a norlanostane-triterpenoid oligoglycoside from the Palauan marine sponge Asteropus sarasinosum.
T33401	Missourin
	Missouri is a triterpenoid derived from the root of the Missouri iris. In addition, two known triterpenes, iso-iridogermanal, and zeorin, were isolated and identified.
TP2438	Sarasinoside B1	Sarasinoside-B1
	Sarasinoside B1 is a norlanostane-triterpenoid oligoglycoside from the Palauan marine sponge Asteropus sarasinosum.
T33650	Netzahualcoyondiol
	Netzahualcoyondiol is a triterpenoid natural product that can be isolated from the root bark of Cheiloclinium cognatum.
T31903	Galphimine B
	Galphimine B is a cyclodesiccated triterpenoid from Galphimia Glauca, which can regulate the synaptic transmission of dopaminergic ventral tegmental neurons and has a sedative effect.
T25357	Eburicone
	Eburicone is a lanosterane-type triterpenoid which can be isolated from balsam fir and has antitumor activity.
T37782	2,3-Indolobetulonic Acid
	2,3-Indolobetulonic acid is pentacyclic triterpenoid derivative of betulonic acid and an inhibitor of α-glucosidase (IC50= 1.8 μM).1 1.Khusnutdinova, E.F., Smirnova, I.E., Kazakova, O.B., et al.Synthesis and evaluation o...
T38088	28-Deoxybetulin methyleneamine
	28-Deoxybetulin methyleneamine is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1It has been used in the synthesis of triterpene derivatives with antiviral activity. 1.Nitz,...
T37781	2,3-Indolobetulin
	2,3-Indolobetulin is a pentacyclic triterpenoid and derivative of betulin .1It has been used in the synthesis of α-glucosidase inhibitors. 1.Khusnutdinova, E.F., Smirnova, I.E., Kazakova, O.B., et al.Synthesis and evalua...
T35693	N-(2-Azidoethyl)betulonamide
	N-(2-Azidoethyl)betulonamide is a pentacyclic triterpenoid, a derivative of betulonic acid , and an intermediate in the synthesis of betulonic acid derivatives within vitrocancer cell cytotoxicity.1 1.Suman, P., Patel, A...
T25000	Acetylaleuritolic acid	NSC 266221,NSC-266221,NSC266221
	Acetylaleuritolic acid is a pentacyclic triterpenoid, plant metabolite isolated from the leaves of Garcinia miniata. It has antitumor properties, showing tumor inhibitory activity in tests against P-388 lymphoblastic leu...
T32287	Jegosapogenol A	Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D
	Jegosapogenol A is a type of triterpenoid. Triterpenoids are terpene molecules containing six isoprene units. Barringtogenol C is a very weakly acidic compound (based on its pKa) and practically insoluble (in water). Bar...
T74243	Tyrosinase/elastase-IN-1
	Tyrosinase/elastase-IN-1, a triterpenoid extracted from the leaves of Rubus fraxinifolius, exhibits inhibitory activities against both tyrosinase and elastase enzymes.
T37039	Betulinic Aldehyde oxime
	Betulinic aldehyde oxime is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1It is active againstE. aerogenes,E. coli,E. faecalis,P. aeruginosa,S. aureus, andC. albicans, as w...
T70029	Ibrexafungerp citrate
	Ibrexafungerp citrate is a triterpenoid antifungal. Similarly to echinocandins, it inhibits the synthesis of 1,3-β-d-glucan. However, it binds to a different site on the enzyme than echinocandins, resulting in limited cr...
T36318	28-Acetylbetulin
	28-Acetylbetulin is a lupane triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin that has been found inM. chiapensisand has anti-inflammatory and anticancer activities.1,2It inhibits LPS-induced...
T78887	ROS-IN-2		Reactive Oxygen Species
	ROS-IN-2 (compound 85), a seco-lupane triterpenoid derivative, inhibits reactive oxygen species (ROS) production and shields mitochondria from oxidative damage by curtailing the generation of oxidative stressors. It has ...		Reactive Oxygen Species
T69244	Betulonaldehyde
	Betulonaldehyde is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin that has been found in Betula. It is active against P. falciparum (IC50 = 3.36 µg/ml) and cytotoxic to NCI H1...
T79757	Meliadubin B		NO Synthase
	Meliadubin B, a natural triterpenoid, effectively inhibits inflammatory responses by suppressing superoxide anion generation in human neutrophils (EC 50 of 5.54 μM) as well as inducible nitric oxide synthase activity. Ad...		NO Synthase

Compounds

Sericoside

T124663

Synonym:

Target: Immunology/Inflammation related

Omaveloxolone

T6919

Synonym: RTA-408

Target: Apoptosis, Others, Nrf2, STING

Bardoxolone Methyl

T6165

Synonym: RTA 402,CDDO Methyl ester,TP-155,NSC 713200

Target: Apoptosis, IκB/IKK, Ferroptosis, Nrf2, Autophagy

CDDO-dhTFEA

T13604

Synonym:

Target: Others, NF-κB, Nrf2

Sapelin B

T34516

Synonym: NSC 270047,NSC270047,NSC-270047

Synonym: (+)-Isobauerenol

Target:

Iguesterin

T32140

Synonym: Isoiguesterin

Target:

Saniculoside R 1

TP2436

Synonym: Saniculoside R-1

Target:

Sarasinoside A1

TP2437

Synonym: Sarasinoside-A1

Synonym: Schizandronic acid,Ganwuweizic acid

Synonym: Sarasinoside-C1

Synonym: Sarasinoside-B1

2,3-Indolobetulonic Acid

T37782

Synonym:

Target:

28-Deoxybetulin methyleneamine

N-(2-Azidoethyl)betulonamide

T35693

Synonym:

Target:

Acetylaleuritolic acid

T25000

Synonym: NSC 266221,NSC-266221,NSC266221

Target:

Jegosapogenol A

T32287

Synonym: Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D

Target:

Tyrosinase/elastase-IN-1

T74243

Synonym:

Target:

Betulinic Aldehyde oxime

T37039

Synonym:

Target:

Ibrexafungerp citrate

Target: Reactive Oxygen Species

カタログ番号	製品名	別名	ターゲット
T2S0501	Ilexgenin A		IL Receptor , TNF
	Ilexgenin A is a novel pentacyclic triterpenoid, is a compound extracted from leaves of Ilex hainanensis Merr		IL Receptor , TNF
T5783	Rosamultin		Antioxidant , HIV Protease
	Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity.		Antioxidant , HIV Protease
T5S1133	Ganoderic acid D		Apoptosis , Sirtuin
	1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(5) value of 17.3 +/- .3 micr...		Apoptosis , Sirtuin
TN6722	Terminolic acid	2α,6β,23-trihydroxyl oleanolic acid	Antibacterial
	Terminolic acid (2α,6β,23-trihydroxyl oleanolic acid) is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum, can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and ...		Antibacterial
TN1109	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid	3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid	NOS , NO Synthase , Prostaglandin Receptor
	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) shows anti-inflammatory activity, it can inhibit NO production and iNOS expression in LPS-stimulated Raw264.7 cells.		NOS , NO Synthase , Prostaglandin Receptor
T6S1676	Cimigenoside		Others
	Cimigenoside is a triterpenoid glycoside from the genus Cimicifuga.		Others
T5775	Cauloside F		Others
	Cauloside F is a triterpenoid saponin found in Clematis akebioides.		Others
T4S1387	Isoescin IA		HIV Protease
	Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. It has anti-HIV-1 protease activity.		HIV Protease
T2S1193	Mogroside III-A1		Others
	Mogroside III-A1 is a triterpenoid glycoside from Siraitia grosvenorii Swingle. Mogroside III-A1 a nonsugar sweetener.		Others
T8300	Mogroside IV-E	mogroside Ive	Antioxidant
	Mogroside IV-E is a triterpenoid glycoside isolated from the extracts of Luo Han Guo. Mogrosides exhibit antidiabetic, antioxidant and anticancer activities.		Antioxidant
T3039	Hederagenin	Hederagenic acid,Astrantiagenin E,Caulosapogenin,Hederagenol	Others
	Hederagenin (Hederagenol) is a triterpenoid saponin inhibiting LPS-stimulated expression of iNOS, COX-2, and NF-κB.		Others
T13640	Dehydroeburicoic acid monoacetate	3-O-Acetyldehydroeburicoic acid	Others
	Dehydroeburicoic acid monoacetate (3-O-Acetyldehydroeburicoic acid) is a triterpenoid of lanolin isolated from Wolfiporia cocos.		Others
TN2337	Poricoic acid AM
	Poricoic acid AM is a triterpenoid compound extracted from Poria cocos, demonstrating anti-tumor activity.
T3910	Pulchinenoside C	Anemoside B4,Chinensioside A,Pulchinenoside B4,Pulsatilla saponin B4	IL Receptor
	Pulchinenoside C (Anemoside B4) is an abundant triterpenoid saponin isolated from P. chinensis and exerts anti-inflammatory and antioxidant effects.		IL Receptor
TN7039	Celosin H		Others
	Celosin H is a novel hepatoprotective triterpenoid saponin isolated from the methanol extract of Celosiae Semen.		Others
T0722	Ursolic acid	Malol,Urson,NSC 167406,NSC-4060,Prunol	Endogenous Metabolite , Autophagy
	Ursolic acid (Prunol)(Bungeolic acid), a natural pentacyclic triterpenoid carboxylic acid, shows anti-tumor effects.		Endogenous Metabolite , Autophagy
T2728	Limonin	Dictamnolactone,Limonoic acid 3,19:16,17 dilactone,Obaculactone,Citrolimonin	Apoptosis , HIV Protease , Endogenous Metabolite
	Limonin (Citrolimonin) is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.		Apoptosis , HIV Protease , Endogenous Metabolite
T2741	Glycyrrhizic acid	Glycyrrhizin	Virus Protease , Dehydrogenase , MAO
	Glycyrrhizic acid (Glycyrrhizin) is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.		Virus Protease , Dehydrogenase , MAO
TCS1188	Mogroside III		Others
	Mogroside III is a triterpenoid glycoside and a nonsugar sweetener. Mogroside III is transformed by human intestinal bacteria to release secondary glycoside mogroside IIA1 and aglycone mogrol.		Others
T12090	Mogroside I E1		Others
	Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.		Others
T4S1848	Tubeimoside II	Tubeimoside-B	Others
	Tubeimoside II (also known as Tubeimoside-B), a natural oleanane-type triterpenoid saponin analogue, exhibits anti-inflammatory, antitumor, and antitumor-promoting properties.		Others
T3S2197	Polygalic acid	Senegenic acid	Others
	Polygalic acid (Senegenic acid), a triterpenoid saponin, is a major active ingredient in Polygala tenuifolia. Polygalic acid shows expectorant, emetic and stimulant effects.		Others
TN7059	Deoxylimonin	NSC 314317,desoxylimonin	Others
	Deoxylimonin (NSC 314317) is a triterpenoid isolated from grapefruit seeds.		Others
TN7060	Methyl oleanonate		PPAR
	3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.		PPAR
TN1866	Licoricesaponin G2
	Licoricesaponin G2 is a pentacyclic triterpenoid derived from Glycyrrhiza aspera, which can be used to differentiate crude liquorice from honey-processed liquorice.
TN1553	Deacetyl ganoderic acid F		Others
	Deacetyl ganoderic acid F (DeGA F), a triterpenoid extracted from Ganoderma lucidum, inhibits lipopolysaccharide (LPS)-induced inflammation in vitro and in vivo.		Others
T3387	Phytolaccagenin		Others , Antibacterial
	Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phtolaccae which are widely used in East Asian countries for the treatment of inflammation-related diseases.		Others , Antibacterial
T19882	Bryonolic acid	UNII-J7YR6A878I,20-epi-Bryonolic acid	Apoptosis , Antioxidant , Calcium Channel
	Bryonolic acid (20-epi-Bryonolic acid), a triterpenoid extracted from Sandoricum indicum, possesses immunomodulatory, anti-inflammatory, antioxidant and anticancer activities and protects PC12 cells from NMDA-induced apo...		Apoptosis , Antioxidant , Calcium Channel
T3918	Ginsenoside Rb3	Gypenoside IV	NF-κB , COX , NO Synthase
	Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits the induction of COX-2 and iNOS mRNA.		NF-κB , COX , NO Synthase
T4970	LANOSTEROL	3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol	Endogenous Metabolite
	Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived.		Endogenous Metabolite
T8846	Beta-Escin	B-escin,AESCINE	Immunology/Inflammation related
	beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.		Immunology/Inflammation related
T3368	Alpha-Hederin	Helixin,Tauroside E,α-Hederin,Hederoside C	Apoptosis , Others
	Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.		Apoptosis , Others
T5575	Cycloastragenol	Cyclogalegenol,Astramembrangenin	Epigenetic Reader Domain , Telomerase
	Astramembrangenin (Cycloastragenol (Astramembrangenin)) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloastragenol (CAG) may have a novel therape...		Epigenetic Reader Domain , Telomerase
T3248	Alpha-Boswellic acid	α-Boswellic acid	Others
	alpha-Boswellic acid (α-Boswellic acid) is a pentacyclic triterpenoid natural product extracted from frankincense and has anticonvulsant and anticancer effects. In animals, it prevents and reduces Alzheimer's disease mar...		Others
TN1219	20-Hydroxyganoderic acid G
	20-Hydroxyganoderic acid G is a lanosterane triterpenoid obtained from the ethanolic extract of Ganoderma curtisii (Ganoderma curtisii) cotyledons. 20-Hydroxyganoderic Acid G inhibited LPS-activated BV-2 microglia, with ...
T2915	Bardoxolone	RTA 401,CDDO	Others , Nrf2
	Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By supp...		Others , Nrf2
TN1013	Cucurbitacin D		Apoptosis
	Cucurbitacin D, a triterpenoid isolated from Ecballium elaterium (L.), exhibits anticancer and antitumor activity, inhibits glucose uptake and lactate production in metastatic PrC, and induces inflammasome activation ind...		Apoptosis
TN1831	Macranthoside A	Kalopanaxsaponin H	Antioxidant
	Macranthoside A (Kalopanaxsaponin H) is a triterpenoid glycoside extracted from rehmannia and belongs to the iridoterpenoid synthesis. Macranthoside A has anti-inflammatory, antioxidant, antibacterial and neuroprotective...		Antioxidant
TN1056	Mogroside IIe		IL Receptor
	Mogroside IIe is a bitter triterpenoid saponin which is the main component of unripe Luo Han Guo fruit and a precursor of the commercially available sweetener mogroside V.		IL Receptor
T40672	Bacoside A2
	Bacoside A2 is a triterpenoid saponin.
T26055	Regelin	Regelin C
	Regelin is an antitumor ursene-type triterpenoid isolated from Tripterygium regelii.
T31912	Ganolucidic acid D	(+)-Ganolucidic acid D
	Ganolucidic acid D, also known as ganolucidate D, is a triterpenoid.
T39245	Poricoic acid BM
	Poricoic acid BM is a lanostane triterpenoid present in the peels of Wolfiporia cocos mushrooms.
T10105	3α-Hydroxymogrol		AMPK
	3α-Hydroxymogrol is a triterpenoid isolated from Siraitia grosvenorii Swingle. It is a potent AMPK activator and enhances AMPK phosphorylation.		AMPK
T38892	3,11,15,23-Tetraoxo-27ξ-lanosta-8,16-dien-26-oic acid
	3,11,15,23-Tetraoxo-27ξ-lanosta-8,16-dien-26-oic acid, a lanostane-type triterpenoid extracted from Antrodia camphorate, is a chemical compound.
TN2446	3-Oxobetulin	Betulone	Antiviral
	Betulone is a triterpenoid. It has a role as a metabolite. It derives from a hydride of a lupane.		Antiviral
TN4014	Esculentoside B		Antifection
	Phytolaccoside B(Esculentoside B) is an antifungal monodesmoside triterpenoid glycoside, it has potent inhibitory activity against agrobacterial plant transformation.		Antifection
T40314	(2α,3β)-Olean-12-ene-2,3-diol
	(2α,3β)-Olean-12-ene-2,3-diol (Compound 3) is a triterpenoid compound that possesses a lupane, oleanane, and ursane skeleton.
T23825	Bryononic acid
	Bryononic acid is a new cucurbitane-type triterpenoid. Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo.
T23774	Bauerenol	NSC 147745,Baurenol
	Bauerenol is a triterpenoid from Indian Suregada angustifolia. It also induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma cells.
------------------------ More ------------------------