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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T10190 | 7-BIA | Phosphatase | |
T3354 | BIA 10-2474 | BIA10-2474 | FAAH , Autophagy |
BIA 10-2474 is a long-acting reversible inhibitor of fatty acid amide hydrolase (FAAH) that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (that is, the rest o... | |||
T26797 | BIA 3-335 | BIA-3-335,BIA3335 | |
BIA 3-335, an inhibition of catechol-O-methyltransferase, could have applications for Parkinson's Disease. | |||
T16398 | Opicapone | BIA 9-1067 | Transferase |
Opicapone (BIA 9-1067) reduces the ATP content of the cells (IC50: 98 μM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for the research of Parkinson's disease and motor fluctuations. | |||
T11238L | Etamicastat hydrochloride | BIA 5-453 hydrochloride | Dehydrogenase |
Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension. | |||
T13383 | Zamicastat | BIA 5-1058 | BCRP , Hydroxylase , P-gp |
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73.8 μM and 17.0 μM, respectively). | |||
T6787 | BIO-acetoxime | BIA,GSK-3 Inhibitor X | Apoptosis , GSK-3 , HSV |
BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B. | |||
T8649 | TMBIM6 antagonist-1 | BAX-inhibitor-1,BIA | mTOR |
TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitor | |||
T3285 | Eslicarbazepine Acetate | Zebinix,Aptiom,BIA 2-093,Exalief,Stedesa | Beta-Secretase , Sodium Channel |
Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conve... | |||
T3285L | Eslicarbazepine | Pazzul,EC 810-248-9,BIA 2-194,Stedesa,Erelib | Beta-Secretase , Sodium Channel |
Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures. | |||
T9156 | CDC25B-IN-2 | Phosphatase , mTOR | |
BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression. | |||
T24958 | (R)-Licarbazepine Acetate | BIA2-059,Licarbazepine acetate, (R)-,BIA 2-059,BIA-2-059 | |
(R)-Licarbazepine Acetate is a hopeful antiepileptic drug structurally related to Carbamazepine and Oxcarbazepine. | |||
T11238 | Etamicastat | BIA 5-453 | Dehydrogenase |
Etamicastat can be used in the research of cardiovascular diseases. Etamicastat (BIA 5-453) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor with an IC50 value of 107 nM. | |||
T16279 | Nebicapone | BIA 3-202 | Others |
Nebicapone is a reversible catechol-O-methyltransferase (COMT) inhibitor and is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to ... | |||
T7806 | Licarbazepine | 10,11-hydroxy-10,11 Dihydrocarbamezer | Others |
Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders. | |||
T6411 | Biapenem | CLI 86815,Biapenern,Omegacin,L 627,LJC 10627 | Antibacterial , Antibiotic |
Biapenem (CLI 86815) is a 1-beta-methylcarbapenem antibiotic with a wide range of antibacterial activity. Biapenem has similar antibacterial activity to that of imipenem, but is more stable against human renal dehydropep... | |||
T72358 | Antimicrobial agent-14 | Antibacterial | |
Antimicrobial agent-14 is a benzyl thiophene sulfonamide derivative that is often used as an antimicrobial agent.Antimicrobial agent-14 has a MIC value of 200 μM against Campylobacter coli ATCC33559, which can be used to... | |||
T67942 | Antimicrobial agent-21 | MAPK | |
Antimicrobial agent-21 is a potent mitogen activated protein kinase inhibitor with antibacterial, anti-inflammatory and antitumor activity for the treatment of cataracts, ulcerative colitis, meningitis and Kawasaki's dis... | |||
T10337 | Antimicrobial Compound 1 | Antibacterial | |
Antimicrobial Compound 1 is an alkyl pyridinium compound with Tail 12C, Head 4-carboxyl. Antimicrobial Compound 1 exhibits antimicrobial activities against B. subtilis and E. coli. | |||
T30442 | Bialamicol Hydrochloride | Camoform hydrochloride,CAM 807,CAM-807,CI 301 | |
Bialomicol Hydrochloride is a bio-active chemical. | |||
T79468 | Antimicrobial agent-22 | ||
Antimicrobial agent-22 (THI 6c) constitutes a broad-spectrum, multi-target antibacterial with notable rapid bactericidal efficacy and effective anti-biofilm activity, paired with low cytotoxicity and hemolytic properties... | |||
T75653 | (±)-Columbianetin | Dihydrooroselol | |
Columbianetin, a phytoalexin found in celery (Apium graveolens), plays a crucial role in the plant's resistance to pathogens during storage. It demonstrates significant anti-fungal and anti-inflammatory properties [1] [2... | |||
T79595 | Antimicrobial agent-24 | ||
Compound E8 (Antimicrobial agent-24) is a hydrazide with broad-spectrum fungicidal properties, disrupting the plasma membrane's functionality and inducing morphological and subcellular structural changes in mycelia [1]. | |||
T125686 | Euphorbia factor L22 | ||
Euphorbia factor L22 is a useful organic compound for research related to life sciences and the catalog number is T125686. | |||
T125685 | Euphorbia factor L24 | ||
Euphorbia factor L24 is a useful organic compound for research related to life sciences and the catalog number is T125685. | |||
T72413 | Antimicrobial agent-6 | ||
Antimicrobial Agent-6, exhibiting a minimum inhibitory concentration (MIC) range of 4-8 μg/mL, is effective against both gram-positive and gram-negative bacteria. Additionally, it demonstrates anti-inflammatory propertie... | |||
T60963 | Antimicrobial agent-2 | ||
Antimicrobial agent-2 (compound V-a) inhibits against various Gram-positive and -negative bacteria that is broad-spectrum antimicrobial agent with low toxicity, no obvious resistance and good bioavailability. Antimicrobi... | |||
T74967 | Antimicrobial agent-11 | ||
Antimicrobial agent-11 is a SARS-CoV-2 inhibitor with antibacterial activity [1] . | |||
T124821 | Rubiarbonone E | ||
Rubiarbonone E is a useful organic compound for research related to life sciences. The catalog number is T124821 and the CAS number is 468732-43-6. | |||
T125089 | Euphorbia factor L25 | ||
Euphorbia factor L25 is a useful organic compound for research related to life sciences and the catalog number is T125089. | |||
T131613 | Byakangelicol (Biacangelicol) | ||
Byakangelicol (Biacangelicol) is a useful organic compound for research related to life sciences and the catalog number is T131613. | |||
T31959 | Glycobiarsol | ||
Glycobiarsol is used for the control of Trichuris vulpis infection. | |||
T61783 | Antimicrobial agent-1 | ||
Antimicrobial Agent-1 (compound 6C) shows strong activity (MIC = 2 μg/mL) against TolC mutant E. coli. Additionally, it synergistically interacts with Colistin to exhibit enhanced activity against Gram-negative bacteria.... | |||
T74966 | Antimicrobial agent-10 | ||
Antimicrobial Agent-10 demonstrates exceptional antibacterial activity and inhibits SARS-CoV-2, positioning it as a potent antimicrobial compound [1]. | |||
T74953 | Antimicrobial agent-7 | ||
Antimicrobial Agent-7 (Compound 12) serves as a potent antimicrobial with an MIC range of 2-8 μg/mL effective against both Gram-positive and Gram-negative bacteria. Additionally, it demonstrates anti-inflammatory propert... | |||
T76653 | Polybia-MP1 | ||
Polybia-MP1 is an antimicrobial mastoparan peptide [1] . | |||
T124707 | (R)-(-)-Columbianetin | R-Columbianetin,R-Dihydrooroselol,(R)-(-)-Dihydrooroselol | |
(R)-(-)-Columbianetin is a useful organic compound for research related to life sciences. The catalog number is T124707 and the CAS number is 52842-47-4. | |||
T126086 | Euphorbia factor L9 | ||
Euphorbia factor L9 is a useful organic compound for research related to life sciences and the catalog number is T126086. | |||
T24633 | Phlebiakauranol aldehyde | ||
Phlebiakauranol aldehyde is an antifungal and cytotoxic metabolite. | |||
T125358 | Leonubiastrin | ||
Leonubiastrin is a useful organic compound for research related to life sciences. The catalog number is T125358 and the CAS number is 211686-25-8. | |||
T126025 | Rubiarbonol A 7-acetate | ||
Rubiarbonol A 7-acetate is a useful organic compound for research related to life sciences. The catalog number is T126025 and the CAS number is 1338588-80-9. | |||
T72414 | Antimicrobial agent-8 | ||
Antimicrobial Agent-8 exhibits a high level of antimicrobial efficacy, demonstrating a minimum inhibitory concentration (MIC) range of 2-8 μg/mL against both Gram-negative and Gram-positive bacteria. Furthermore, this co... | |||
T74392 | Antimicrobial photosensitizer-1 | ||
Antimicrobial Photosensitizer-1 demonstrates significant potential as an effective agent for treating infections caused by pathogenic microorganisms, with notable antimicrobial efficacy observed in S. aureus-infected mou... | |||
T83042 | Antimicrobial agent-26 | ||
Antimicrobial agent-26 is a powerful antimicrobial that has demonstrated the ability to counteract antibiotic resistance in vitro [1]. | |||
T34437 | Rubiatriol | ||
Rubiatriol is a triterpenoid isolated from the root of Rubia cordifolia L. | |||
T60462 | Antimicrobial agent-3 | ||
Antimicrobial agent-3 (Compound U10) is an antimicrobial agent that is used against bacterial, fungal, and tubercular infections [1]. | |||
T72412 | Antimicrobial agent-5 | ||
Antimicrobial Agent-5 is a potent antimicrobial agent that exhibits exceptional cell selectivity against both Gram-negative and Gram-positive bacteria. It inhibits the interaction between LPS (lipopolysaccharide) and the... | |||
T74954 | Antimicrobial agent-9 | ||
Antimicrobial Agent-9 (Compound 16) exhibits antimicrobial properties with a minimum inhibitory concentration (MIC) range of 4-8 μg/mL against both gram-positive and gram-negative bacteria, and also demonstrates anti-inf... | |||
T74968 | Antimicrobial agent-12 | ||
Antimicrobial agent-12 serves as a powerful antibacterial compound that also exhibits inhibitory activity against SARS-CoV-2 [1]. | |||
T80345 | Bovine tracheal antimicrobial peptide | ||
Bovine tracheal antimicrobial peptide, derived from the tracheal mucosa, exhibits antimicrobial efficacy against E. coli D31, K. pneumoniae 13883, S. aureus 25923, P. aeruginosa 27853, and C. albicans 14053, with respect... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T125211 | Deoxy euphorbia factor L1 | Others | |
Deoxy euphorbia factor L1 is a natural product found in the seeds of Euphorbia lathyris L | |||
T3373 | Columbianadin | Zosimin,2-Butenoic acid | Apoptosis |
Columbianadin (Zosimin), one of the main bioactive constituents of the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan, has been found to possess obvious pharmacological effects in previous studies. | |||
TN1640 | Fabiatrin | Others | |
Fabiatrin is a natural product isolated and identified from n-butanol extract of Przewalskia tangutica. | |||
T5S1286 | (+)-Columbianetin | (S)-Columbianetin,Columbianetin | Antifungal |
(+)-Columbianetin ((S)-Columbianetin) is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. (+)-Columbianetin has anti-inflammatory effect... | |||
T5798 | Euphorbia Factor L2 | euphorbiafactor L2 | Apoptosis , NF-κB |
Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation. | |||
T2S0410 | Euphorbia factor L1 | Euphorbiasteroid | Apoptosis , P-gp |
Euphorbia factor L1 (Euphorbiasteroid) can reduce Bcl-2, PI3K, AKT, and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels. It induces autophagy and has anti-cancer, anti-adipogenic, ant... | |||
T8671 | Bianthrone | Others | |
Bianthrone is a natural product. | |||
TN1635 | Euphorbia factor L8 | Others | |
Euphorbia factor L8 is a natural product | |||
T4237 | Rubiadin-1-methyl ether | Rubiadin 1-methyl ether | Anti-infection , NF-κB |
Rubiadin-1-methyl ether (Rubiadin 1-methyl ether) is a natural product.It inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nu... | |||
TN1634 | Euphorbia factor L7b | Others | |
Euphorbia factor L7b,a natural product obtained from the herbs of Euphorbia pekinensis Rupr. | |||
T3220 | Euphorbiasteroid | Euphobiasteroid,Euphorbia factor L1 | Others , AMPK |
Euphorbiasteroid (Euphobiasteroid) (25-50 μM) decreased differentiation of 3T3-L1 cells via reduction of intracellular triglyceride (TG) accumulation. | |||
T4241 | Rubiadin | 1,3-Dihydroxy-2-Methylanthracene-9,10-Dione | Free radical scavengers , PARP , Caspase |
Rubiadin (1,3-Dihydroxy-2-Methylanthracene-9,10-Dione) possesses potent antioxidant property, it can prevent lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner. | |||
T4946 | (+)-Columbianetin acetate | COLUMBIANETIN ACETATE | Others |
(+)-Columbianetin acetate (COLUMBIANETIN ACETATE) may be helpful in regulating mast cell-mediated allergic inflammatory responses.The absorption of (+)-Columbianetin acetate is a passive diffusion process without pH-depe... | |||
TN4922 | Rubiarbonol B | Others | |
Rubiarbonol B may have antiplatelet aggregation activities. | |||
T82718 | Cis-Emodin bianthrone | ||
Cis-Emodin bianthrone (compound 4) is a highly condensed oxygen-containing emodin anthrone derivative that remains stable in acetone solution when exposed to air [1]. | |||
T79997 | (±)-Emodin bianthrone | Parasite | |
(±)-Emodin bianthrone (compound 10), a naturally occurring substance, demonstrates antimalarial, antitubercular, and antifungal properties [1]. | |||
TN1633 | Euphorbia factor L7a | Others | |
Euphorbia factor L7a is a natural product | |||
T83041 | Antimicrobial agent-27 | ||
Could you provide the description of the chemical compound that you would like me to rewrite? Without the original text, I'm unable to provide an improved version. | |||
TN6469 | Biatractylolide | ||
Biatractylolide has a neuroprotective effect on glutamate-induced injury in PC12 and SH-SY5Y cells through a mechanism of the PI3K-Akt-GSK3β-dependent pathways. The molecular mechanisms of inhibitory activities of biatra... | |||
TN6472 | Columbianetin beta-D-glucopyranoside | ||
Columbianetin-beta-D-glucopyranoside exhibits anti-inflammatory and analgesic properties, it also shows strong inhibiting activity against platelet aggregation. | |||
TN5500 | 3',3'''-Biapigenin | ||
3',3'''-Biapigenin is a natural product for research related to life sciences. The catalog number is TN5500 and the CAS number is 151455-26-4. | |||
TN1241 | 3,8''-Biapigenin | 3,8'-Biapigenin | ROS |
3, 8''-Biapigenin can modulate intracellular ROS production. | |||
TN5628 | Rubianthraquinone | ||
Rubianthraquinone is a natural product from Rubia yunnanensis. | |||
T40595 | Rubiayannone A | ||
Rubiayannone A is an anthraquinone glycoside with an antiplatelet aggregation activity. | |||
TN5496 | 2'',3''-Dihydro-3',3'''-biapigenin | 2,3-Dihydro-3',3'''-biapigenin | |
2'',3''-Dihydro-3',3'''-biapigenin is a natural product for research related to life sciences. The catalog number is TN5496 and the CAS number is 151455-25-3. | |||
TN1316 | 6-Hydroxyrubiadin | Others | |
6-Hydroxyrubiadin has antioxidant activity, EC(50) is 14.7ug/ml. | |||
TN4826 | Prerubialatin | Others | |
Prerubialatin is a precursor of rubialatins A and B. |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-01710 | IkB alpha/NFKBIA Protein, Human, Recombinant (His) | Human | E. coli |
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkB alpha, NFKBIA, or IKBA), is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NF... | |||
TMPH-00314 | Lingual antimicrobial peptide Protein, Bubalus bubalis, Recombinant (His & KSI) | Bubalus bubalis | E. coli |
Has bactericidal activity. | |||
TMPH-01058 | Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. | |||
TMPH-00419 | Microbial collagenase Protein, Clostridium perfringens, Recombinant (His & Myc) | Clostridium perfringens | E. coli |
Microbial collagenase Protein, Clostridium perfringens, Recombinant (His & Myc) is expressed in E. coli. |
カタログ番号 | 製品名 | ||
---|---|---|---|
L6500 | Microbial Natural Product Library | 560 compounds | |
A unique collection of 560 microbial natural products for high throughput screening (HTS) and high content screening (HCS); | |||
L2540 | Gut Microbial Metabolite Library | 614 compounds | |
A unique collection of 614 gut microbial metabolites which can be used for HTS and HCS; |