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Search Results for " BIA "

ターゲット

51

阻害剤

27

天然化合物

4

リコンビナントタンパク質

2

ライブラリー

カタログ番号 製品名 別名 ターゲット
T10190 7-BIA Phosphatase
T3354 BIA 10-2474 BIA10-2474 FAAH , Autophagy
BIA 10-2474 is a long-acting reversible inhibitor of fatty acid amide hydrolase (FAAH) that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (that is, the rest o...
T26797 BIA 3-335 BIA-3-335,BIA3335
BIA 3-335, an inhibition of catechol-O-methyltransferase, could have applications for Parkinson's Disease.
T16398 Opicapone BIA 9-1067 Transferase
Opicapone (BIA 9-1067) reduces the ATP content of the cells (IC50: 98 μM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for the research of Parkinson's disease and motor fluctuations.
T11238L Etamicastat hydrochloride BIA 5-453 hydrochloride Dehydrogenase
Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.
T13383 Zamicastat BIA 5-1058 BCRP , Hydroxylase , P-gp
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73.8 μM and 17.0 μM, respectively).
T6787 BIO-acetoxime BIA,GSK-3 Inhibitor X Apoptosis , GSK-3 , HSV
BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.
T8649 TMBIM6 antagonist-1 BAX-inhibitor-1,BIA mTOR
TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitor
T3285 Eslicarbazepine Acetate Zebinix,Aptiom,BIA 2-093,Exalief,Stedesa Beta-Secretase , Sodium Channel
Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conve...
T3285L Eslicarbazepine Pazzul,EC 810-248-9,BIA 2-194,Stedesa,Erelib Beta-Secretase , Sodium Channel
Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures.
T9156 CDC25B-IN-2 Phosphatase , mTOR
BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression.
T24958 (R)-Licarbazepine Acetate BIA2-059,Licarbazepine acetate, (R)-,BIA 2-059,BIA-2-059
(R)-Licarbazepine Acetate is a hopeful antiepileptic drug structurally related to Carbamazepine and Oxcarbazepine.
T11238 Etamicastat BIA 5-453 Dehydrogenase
Etamicastat can be used in the research of cardiovascular diseases. Etamicastat (BIA 5-453) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor with an IC50 value of 107 nM.
T16279 Nebicapone BIA 3-202 Others
Nebicapone is a reversible catechol-O-methyltransferase (COMT) inhibitor and is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to ...
T7806 Licarbazepine ​10,11-hydroxy-10,11 Dihydrocarbamezer Others
Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders.
T6411 Biapenem CLI 86815,Biapenern,Omegacin,L 627,LJC 10627 Antibacterial , Antibiotic
Biapenem (CLI 86815) is a 1-beta-methylcarbapenem antibiotic with a wide range of antibacterial activity. Biapenem has similar antibacterial activity to that of imipenem, but is more stable against human renal dehydropep...
T72358 Antimicrobial agent-14 Antibacterial
Antimicrobial agent-14 is a benzyl thiophene sulfonamide derivative that is often used as an antimicrobial agent.Antimicrobial agent-14 has a MIC value of 200 μM against Campylobacter coli ATCC33559, which can be used to...
T67942 Antimicrobial agent-21 MAPK
Antimicrobial agent-21 is a potent mitogen activated protein kinase inhibitor with antibacterial, anti-inflammatory and antitumor activity for the treatment of cataracts, ulcerative colitis, meningitis and Kawasaki's dis...
T10337 Antimicrobial Compound 1 Antibacterial
Antimicrobial Compound 1 is an alkyl pyridinium compound with Tail 12C, Head 4-carboxyl. Antimicrobial Compound 1 exhibits antimicrobial activities against B. subtilis and E. coli.
T30442 Bialamicol Hydrochloride Camoform hydrochloride,CAM 807,CAM-807,CI 301
Bialomicol Hydrochloride is a bio-active chemical.
T79468 Antimicrobial agent-22
Antimicrobial agent-22 (THI 6c) constitutes a broad-spectrum, multi-target antibacterial with notable rapid bactericidal efficacy and effective anti-biofilm activity, paired with low cytotoxicity and hemolytic properties...
T75653 (±)-Columbianetin Dihydrooroselol
Columbianetin, a phytoalexin found in celery (Apium graveolens), plays a crucial role in the plant's resistance to pathogens during storage. It demonstrates significant anti-fungal and anti-inflammatory properties [1] [2...
T79595 Antimicrobial agent-24
Compound E8 (Antimicrobial agent-24) is a hydrazide with broad-spectrum fungicidal properties, disrupting the plasma membrane's functionality and inducing morphological and subcellular structural changes in mycelia [1].
T125686 Euphorbia factor L22
Euphorbia factor L22 is a useful organic compound for research related to life sciences and the catalog number is T125686.
T125685 Euphorbia factor L24
Euphorbia factor L24 is a useful organic compound for research related to life sciences and the catalog number is T125685.
T72413 Antimicrobial agent-6
Antimicrobial Agent-6, exhibiting a minimum inhibitory concentration (MIC) range of 4-8 μg/mL, is effective against both gram-positive and gram-negative bacteria. Additionally, it demonstrates anti-inflammatory propertie...
T60963 Antimicrobial agent-2
Antimicrobial agent-2 (compound V-a) inhibits against various Gram-positive and -negative bacteria that is broad-spectrum antimicrobial agent with low toxicity, no obvious resistance and good bioavailability. Antimicrobi...
T74967 Antimicrobial agent-11
Antimicrobial agent-11 is a SARS-CoV-2 inhibitor with antibacterial activity [1] .
T124821 Rubiarbonone E
Rubiarbonone E is a useful organic compound for research related to life sciences. The catalog number is T124821 and the CAS number is 468732-43-6.
T125089 Euphorbia factor L25
Euphorbia factor L25 is a useful organic compound for research related to life sciences and the catalog number is T125089.
T131613 Byakangelicol (Biacangelicol)
Byakangelicol (Biacangelicol) is a useful organic compound for research related to life sciences and the catalog number is T131613.
T31959 Glycobiarsol
Glycobiarsol is used for the control of Trichuris vulpis infection.
T61783 Antimicrobial agent-1
Antimicrobial Agent-1 (compound 6C) shows strong activity (MIC = 2 μg/mL) against TolC mutant E. coli. Additionally, it synergistically interacts with Colistin to exhibit enhanced activity against Gram-negative bacteria....
T74966 Antimicrobial agent-10
Antimicrobial Agent-10 demonstrates exceptional antibacterial activity and inhibits SARS-CoV-2, positioning it as a potent antimicrobial compound [1].
T74953 Antimicrobial agent-7
Antimicrobial Agent-7 (Compound 12) serves as a potent antimicrobial with an MIC range of 2-8 μg/mL effective against both Gram-positive and Gram-negative bacteria. Additionally, it demonstrates anti-inflammatory propert...
T76653 Polybia-MP1
Polybia-MP1 is an antimicrobial mastoparan peptide [1] .
T124707 (R)-(-)-Columbianetin R-Columbianetin,R-Dihydrooroselol,(R)-(-)-Dihydrooroselol
(R)-(-)-Columbianetin is a useful organic compound for research related to life sciences. The catalog number is T124707 and the CAS number is 52842-47-4.
T126086 Euphorbia factor L9
Euphorbia factor L9 is a useful organic compound for research related to life sciences and the catalog number is T126086.
T24633 Phlebiakauranol aldehyde
Phlebiakauranol aldehyde is an antifungal and cytotoxic metabolite.
T125358 Leonubiastrin
Leonubiastrin is a useful organic compound for research related to life sciences. The catalog number is T125358 and the CAS number is 211686-25-8.
T126025 Rubiarbonol A 7-acetate
Rubiarbonol A 7-acetate is a useful organic compound for research related to life sciences. The catalog number is T126025 and the CAS number is 1338588-80-9.
T72414 Antimicrobial agent-8
Antimicrobial Agent-8 exhibits a high level of antimicrobial efficacy, demonstrating a minimum inhibitory concentration (MIC) range of 2-8 μg/mL against both Gram-negative and Gram-positive bacteria. Furthermore, this co...
T74392 Antimicrobial photosensitizer-1
Antimicrobial Photosensitizer-1 demonstrates significant potential as an effective agent for treating infections caused by pathogenic microorganisms, with notable antimicrobial efficacy observed in S. aureus-infected mou...
T83042 Antimicrobial agent-26
Antimicrobial agent-26 is a powerful antimicrobial that has demonstrated the ability to counteract antibiotic resistance in vitro [1].
T34437 Rubiatriol
Rubiatriol is a triterpenoid isolated from the root of Rubia cordifolia L.
T60462 Antimicrobial agent-3
Antimicrobial agent-3 (Compound U10) is an antimicrobial agent that is used against bacterial, fungal, and tubercular infections [1].
T72412 Antimicrobial agent-5
Antimicrobial Agent-5 is a potent antimicrobial agent that exhibits exceptional cell selectivity against both Gram-negative and Gram-positive bacteria. It inhibits the interaction between LPS (lipopolysaccharide) and the...
T74954 Antimicrobial agent-9
Antimicrobial Agent-9 (Compound 16) exhibits antimicrobial properties with a minimum inhibitory concentration (MIC) range of 4-8 μg/mL against both gram-positive and gram-negative bacteria, and also demonstrates anti-inf...
T74968 Antimicrobial agent-12
Antimicrobial agent-12 serves as a powerful antibacterial compound that also exhibits inhibitory activity against SARS-CoV-2 [1].
T80345 Bovine tracheal antimicrobial peptide
Bovine tracheal antimicrobial peptide, derived from the tracheal mucosa, exhibits antimicrobial efficacy against E. coli D31, K. pneumoniae 13883, S. aureus 25923, P. aeruginosa 27853, and C. albicans 14053, with respect...

Compounds

7-BIA
T10190
Synonym:
Target: Phosphatase
BIA 10-2474
T3354
Synonym: BIA10-2474
Target: FAAH, Autophagy
BIA 3-335
T26797
Synonym: BIA-3-335,BIA3335
Target:
Opicapone
T16398
Synonym: BIA 9-1067
Target: Transferase
Etamicastat hydrochloride
T11238L
Synonym: BIA 5-453 hydrochloride
Target: Dehydrogenase
Zamicastat
T13383
Synonym: BIA 5-1058
Target: BCRP, Hydroxylase, P-gp
BIO-acetoxime
T6787
Synonym: BIA,GSK-3 Inhibitor X
Target: Apoptosis, GSK-3, HSV
TMBIM6 antagonist-1
T8649
Synonym: BAX-inhibitor-1,BIA
Target: mTOR
Eslicarbazepine Acetate
T3285
Synonym: Zebinix,Aptiom,BIA 2-093,Exalief,Stedesa
Target: Beta-Secretase, Sodium Channel
Eslicarbazepine
T3285L
Synonym: Pazzul,EC 810-248-9,BIA 2-194,Stedesa,Erelib
Target: Beta-Secretase, Sodium Channel
CDC25B-IN-2
T9156
Synonym:
Target: Phosphatase, mTOR
(R)-Licarbazepine Acetate
T24958
Synonym: BIA2-059,Licarbazepine acetate, (R)-,BIA 2-059,BIA-2-059
Target:
Etamicastat
T11238
Synonym: BIA 5-453
Target: Dehydrogenase
Nebicapone
T16279
Synonym: BIA 3-202
Target: Others
Licarbazepine
T7806
Synonym: ​10,11-hydroxy-10,11 Dihydrocarbamezer
Target: Others
Biapenem
T6411
Synonym: CLI 86815,Biapenern,Omegacin,L 627,LJC 10627
Target: Antibacterial, Antibiotic
Antimicrobial agent-14
T72358
Synonym:
Target: Antibacterial
Antimicrobial agent-21
T67942
Synonym:
Target: MAPK
Antimicrobial Compound 1
T10337
Synonym:
Target: Antibacterial
Bialamicol Hydrochloride
T30442
Synonym: Camoform hydrochloride,CAM 807,CAM-807,CI 301
Target:
Antimicrobial agent-22
T79468
Synonym:
Target:
(±)-Columbianetin
T75653
Synonym: Dihydrooroselol
Target:
Antimicrobial agent-24
T79595
Synonym:
Target:
Euphorbia factor L22
T125686
Synonym:
Target:
Euphorbia factor L24
T125685
Synonym:
Target:
Antimicrobial agent-6
T72413
Synonym:
Target:
Antimicrobial agent-2
T60963
Synonym:
Target:
Antimicrobial agent-11
T74967
Synonym:
Target:
Rubiarbonone E
T124821
Synonym:
Target:
Euphorbia factor L25
T125089
Synonym:
Target:
Byakangelicol (Biacangelicol)
T131613
Synonym:
Target:
Glycobiarsol
T31959
Synonym:
Target:
Antimicrobial agent-1
T61783
Synonym:
Target:
Antimicrobial agent-10
T74966
Synonym:
Target:
Antimicrobial agent-7
T74953
Synonym:
Target:
Polybia-MP1
T76653
Synonym:
Target:
(R)-(-)-Columbianetin
T124707
Synonym: R-Columbianetin,R-Dihydrooroselol,(R)-(-)-Dihydrooroselol
Target:
Euphorbia factor L9
T126086
Synonym:
Target:
Phlebiakauranol aldehyde
T24633
Synonym:
Target:
Leonubiastrin
T125358
Synonym:
Target:
Rubiarbonol A 7-acetate
T126025
Synonym:
Target:
Antimicrobial agent-8
T72414
Synonym:
Target:
Antimicrobial photosensitizer-1
T74392
Synonym:
Target:
Antimicrobial agent-26
T83042
Synonym:
Target:
Rubiatriol
T34437
Synonym:
Target:
Antimicrobial agent-3
T60462
Synonym:
Target:
Antimicrobial agent-5
T72412
Synonym:
Target:
Antimicrobial agent-9
T74954
Synonym:
Target:
Antimicrobial agent-12
T74968
Synonym:
Target:
Bovine tracheal antimicrobial peptide
T80345
Synonym:
Target:
1 2
カタログ番号 製品名 別名 ターゲット
T125211 Deoxy euphorbia factor L1 Others
Deoxy euphorbia factor L1 is a natural product found in the seeds of Euphorbia lathyris L
T3373 Columbianadin Zosimin,2-Butenoic acid Apoptosis
Columbianadin (Zosimin), one of the main bioactive constituents of the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan, has been found to possess obvious pharmacological effects in previous studies.
TN1640 Fabiatrin Others
Fabiatrin is a natural product isolated and identified from n-butanol extract of Przewalskia tangutica.
T5S1286 (+)-Columbianetin (S)-Columbianetin,Columbianetin Antifungal
(+)-Columbianetin ((S)-Columbianetin) is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. (+)-Columbianetin has anti-inflammatory effect...
T5798 Euphorbia Factor L2 euphorbiafactor L2 Apoptosis , NF-κB
Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.
T2S0410 Euphorbia factor L1 Euphorbiasteroid Apoptosis , P-gp
Euphorbia factor L1 (Euphorbiasteroid) can reduce Bcl-2, PI3K, AKT, and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels. It induces autophagy and has anti-cancer, anti-adipogenic, ant...
T8671 Bianthrone Others
Bianthrone is a natural product.
TN1635 Euphorbia factor L8 Others
Euphorbia factor L8 is a natural product
T4237 Rubiadin-1-methyl ether Rubiadin 1-methyl ether Anti-infection , NF-κB
Rubiadin-1-methyl ether (Rubiadin 1-methyl ether) is a natural product.It inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nu...
TN1634 Euphorbia factor L7b Others
Euphorbia factor L7b,a natural product obtained from the herbs of Euphorbia pekinensis Rupr.
T3220 Euphorbiasteroid Euphobiasteroid,Euphorbia factor L1 Others , AMPK
Euphorbiasteroid (Euphobiasteroid) (25-50 μM) decreased differentiation of 3T3-L1 cells via reduction of intracellular triglyceride (TG) accumulation.
T4241 Rubiadin 1,3-Dihydroxy-2-Methylanthracene-9,10-Dione Free radical scavengers , PARP , Caspase
Rubiadin (1,3-Dihydroxy-2-Methylanthracene-9,10-Dione) possesses potent antioxidant property, it can prevent lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner.
T4946 (+)-Columbianetin acetate COLUMBIANETIN ACETATE Others
(+)-Columbianetin acetate (COLUMBIANETIN ACETATE) may be helpful in regulating mast cell-mediated allergic inflammatory responses.The absorption of (+)-Columbianetin acetate is a passive diffusion process without pH-depe...
TN4922 Rubiarbonol B Others
Rubiarbonol B may have antiplatelet aggregation activities.
T82718 Cis-Emodin bianthrone
Cis-Emodin bianthrone (compound 4) is a highly condensed oxygen-containing emodin anthrone derivative that remains stable in acetone solution when exposed to air [1].
T79997 (±)-Emodin bianthrone Parasite
(±)-Emodin bianthrone (compound 10), a naturally occurring substance, demonstrates antimalarial, antitubercular, and antifungal properties [1].
TN1633 Euphorbia factor L7a Others
Euphorbia factor L7a is a natural product
T83041 Antimicrobial agent-27
Could you provide the description of the chemical compound that you would like me to rewrite? Without the original text, I'm unable to provide an improved version.
TN6469 Biatractylolide
Biatractylolide has a neuroprotective effect on glutamate-induced injury in PC12 and SH-SY5Y cells through a mechanism of the PI3K-Akt-GSK3β-dependent pathways. The molecular mechanisms of inhibitory activities of biatra...
TN6472 Columbianetin beta-D-glucopyranoside
Columbianetin-beta-D-glucopyranoside exhibits anti-inflammatory and analgesic properties, it also shows strong inhibiting activity against platelet aggregation.
TN5500 3',3'''-Biapigenin
3',3'''-Biapigenin is a natural product for research related to life sciences. The catalog number is TN5500 and the CAS number is 151455-26-4.
TN1241 3,8''-Biapigenin 3,8'-Biapigenin ROS
3, 8''-Biapigenin can modulate intracellular ROS production.
TN5628 Rubianthraquinone
Rubianthraquinone is a natural product from Rubia yunnanensis.
T40595 Rubiayannone A
Rubiayannone A is an anthraquinone glycoside with an antiplatelet aggregation activity.
TN5496 2'',3''-Dihydro-3',3'''-biapigenin 2,3-Dihydro-3',3'''-biapigenin
2'',3''-Dihydro-3',3'''-biapigenin is a natural product for research related to life sciences. The catalog number is TN5496 and the CAS number is 151455-25-3.
TN1316 6-Hydroxyrubiadin Others
6-Hydroxyrubiadin has antioxidant activity, EC(50) is 14.7ug/ml.
TN4826 Prerubialatin Others
Prerubialatin is a precursor of rubialatins A and B.

天然物製品

Deoxy euphorbia factor L1
T125211
Synonym:
Target: Others
Columbianadin
T3373
Synonym: Zosimin,2-Butenoic acid
Target: Apoptosis
Fabiatrin
TN1640
Synonym:
Target: Others
(+)-Columbianetin
T5S1286
Synonym: (S)-Columbianetin,Columbianetin
Target: Antifungal
Euphorbia Factor L2
T5798
Synonym: euphorbiafactor L2
Target: Apoptosis, NF-κB
Euphorbia factor L1
T2S0410
Synonym: Euphorbiasteroid
Target: Apoptosis, P-gp
Bianthrone
T8671
Synonym:
Target: Others
Euphorbia factor L8
TN1635
Synonym:
Target: Others
Rubiadin-1-methyl ether
T4237
Synonym: Rubiadin 1-methyl ether
Target: Anti-infection, NF-κB
Euphorbia factor L7b
TN1634
Synonym:
Target: Others
Euphorbiasteroid
T3220
Synonym: Euphobiasteroid,Euphorbia factor L1
Target: Others, AMPK
Rubiadin
T4241
Synonym: 1,3-Dihydroxy-2-Methylanthracene-9,10-Dione
Target: Free radical scavengers, PARP, Caspase
(+)-Columbianetin acetate
T4946
Synonym: COLUMBIANETIN ACETATE
Target: Others
Rubiarbonol B
TN4922
Synonym:
Target: Others
cis-Emodin bianthrone
T82718
Synonym:
Target:
(±)-Emodin bianthrone
T79997
Synonym:
Target: Parasite
Euphorbia factor L7a
TN1633
Synonym:
Target: Others
Antimicrobial agent-27
T83041
Synonym:
Target:
Biatractylolide
TN6469
Synonym:
Target:
Columbianetin beta-D-glucopyranoside
TN6472
Synonym:
Target:
3',3'''-Biapigenin
TN5500
Synonym:
Target:
3,8''-Biapigenin
TN1241
Synonym: 3,8'-Biapigenin
Target: ROS
Rubianthraquinone
TN5628
Synonym:
Target:
Rubiayannone A
T40595
Synonym:
Target:
2'',3''-Dihydro-3',3'''-biapigenin
TN5496
Synonym: 2,3-Dihydro-3',3'''-biapigenin
Target:
6-Hydroxyrubiadin
TN1316
Synonym:
Target: Others
Prerubialatin
TN4826
Synonym:
Target: Others

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-01710 IkB alpha/NFKBIA Protein, Human, Recombinant (His) Human E. coli
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkB alpha, NFKBIA, or IKBA), is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NF...
TMPH-00314 Lingual antimicrobial peptide Protein, Bubalus bubalis, Recombinant (His & KSI) Bubalus bubalis E. coli
Has bactericidal activity.
TMPH-01058 Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO) Human E. coli
Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
TMPH-00419 Microbial collagenase Protein, Clostridium perfringens, Recombinant (His & Myc) Clostridium perfringens E. coli
Microbial collagenase Protein, Clostridium perfringens, Recombinant (His & Myc) is expressed in E. coli.
カタログ番号 製品名
L6500 Microbial Natural Product Library

560 compounds
A unique collection of 560 microbial natural products for high throughput screening (HTS) and high content screening (HCS);
L2540 Gut Microbial Metabolite Library

614 compounds
A unique collection of 614 gut microbial metabolites which can be used for HTS and HCS;