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T83879 |
1-Arachidoyl Lysophosphatidic Acid sodium
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1-Arachidoyl LPA,LPA(20:0),1-Eicosanoyl-Lysophosphatidic Acid |
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1-Arachidoyl lysophosphatidic acid (1-arachidoyl LPA), a glycerophospholipid with arachidic acid at the sn-1 position, functions as an agonist for lysophosphatidic acid receptor 1 (LPA1). It effectively induces calcium m... |
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T77789 |
Oleoyl-L-alpha-lysophosphatidic acid sodium salt
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LPA sodium salt |
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Oleoyl-L-alpha-lysophosphatidic acid sodium salt is an essential cell membrane biosynthetic metabolite that mediates signal transduction by interacting with G protein-coupled receptors (GPCRs) (ie, LPA receptors). It is ... |
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T31101 |
CRT0273750
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CRT 0273750,CRT-0273750 |
PDE
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CRT0273750 regulates plasma LPA levels and is suitable for in vivo studies. CRT0273750 is an autotaxin (ATX) inhibitor with IC50 of 0.014 μM. |
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T23438 |
TC LPA5 4
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LPA Receptor
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TC LPA5 4 is a LPA5 receptor antagonist. |
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T22834 |
H2L 5765834
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LPA Receptor
,
LPL Receptor
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H2L 5765834 is a lysophosphatidic acid receptors antagonist |
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T15785 |
LPA1 receptor antagonist 1
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LPA1 R antagonist 1 |
LPA Receptor
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LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopathic pulmonary fibrosis. |
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T36907 |
1-Oleoyl Lysophosphatidic Acid
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Oleoyl-sn-3-Glycerophosphate,1-Oleoyl LPA,1-Oleoyl Lysophosphatidic Acid |
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1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through ... |
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T11533 |
Z-HA155
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CS-963 |
PDE
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Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM. |
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T83772 |
1-Linoleoyl Lysophosphatidic Acid sodium
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1-Linoleoyl-2-hydroxy-sn-glycero-3-PA,LPA(18:2),PA(18:2(9Z,12Z)/0:0),1-Octadecadienoyl-2-hydroxy-sn-glycero-3-phosphate,18:2 Lyso PA,1-Octadecadienoyl-2-hydroxy-sn-glycero-3-PA,PA(18:2/0:0),1-Linoleoyl-2-hydroxy-sn-glycero-3-phosphate,1-Linoleoyl LPA |
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1-Linoleoyl lysophosphatidic acid (1-linoleoyl LPA), a glycerophospholipid with linoleic acid at its sn-1 position, acts as an LPA2 receptor agonist and is the predominant LPA form in both mouse and human plasma. This co... |
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T11875 |
LPA2 antagonist 2
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LPA Receptor
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LPA2 antagonist 2 is ＞480-fold more selective than LPA3 (IC50 of 13.85 μM).LPA2 antagonist 2 is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 21.1 nM. |
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T21654 |
1-Oleoyl lysophosphatidic acid sodium
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1-Oleoyl lysophosphatidic acid sodium salt |
LPA Receptor
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1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2 |
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T15786 |
LPA2 antagonist 1
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Hydroxylase
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LPA2 antagonist 1 is an LPA2 antagonist (IC50: 17 nM). |
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T1606 |
Fasudil
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HA-1077,AT877 |
ROCK
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Serine/threonin kinase
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Calcium Channel
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PKA
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PKC
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Autophagy
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Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK. |
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T3060 |
Fasudil hydrochloride
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Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877 |
ROCK
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Serine/threonin kinase
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Calcium Channel
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HIV Protease
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PKA
,
PKC
,
Autophagy
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Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively. |
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TP2056L |
Acetyl-Calpastatin (184-210)(human) acetate
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Acetyl-Calpastatin (184-210) (human) acetate(123714-50-1 Free base ) |
Cysteine Protease
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Acetyl-Calpastatin (184-210)(human) acetate is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin L, respectively. |
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T5670 |
Isobutylparaben
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Others
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Antibacterial
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Isobutylparaben is a preservative and preservative insecticide. |
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T12527L |
Mavodelpar free acid hydrochloride
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Mavodelpar free acid hydrochloride(942594-93-6 Free base),Pparδ agonist HCl,HPP593 free acid HCl,REN001 free acid HCl |
PPAR
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Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist. |
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T4628 |
Seladelpar
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MBX 8025 |
PPAR
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Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia. |
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T3334 |
Velpatasvir
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GS-5816 |
HCV Protease
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SARS-CoV
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Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barrier to resistance in HCV replicon assays. GS-5816 d... |
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T4165 |
Delpazolid
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LCB01-0371 |
Antibacterial
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Antibiotic
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Delpazolid (LCB01-0371), also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomyc... |
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T39516 |
Bocidelpar
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PPAR
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Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells. |
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T5686 |
Isopropylparaben
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Others
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Isopropylparaben is a preservative and preservative insecticide. |
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T71638 |
Isomolpan hydrochloride
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Isomolpan hydrochloride is a dopamine receptor D2 agonist. |
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T39577 |
Fostroxacitabine bralpamide
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MIV-818 |
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Fostroxacitabine bralpamide (MIV-818) is an orally active Troxacitabine-based nucleotide prodrug. Fostroxacitabine bralpamide has anticancer effects. |
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T73088 |
Mavodelpar
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HPP593,REN001,REN001 ; HPP593 |
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Mavodelpar (REN001), a selective PPARδ agonist, effectively suppresses glomerular injury and renal fibrosis. It is utilized in the research of primary mitochondrial myopathies (PMM) and long-chain fatty acid oxidation di... |
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T77140 |
Ralpancizumab
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Ralpancizumab, a selective PCSK9 inhibitor, shows potential for use in hemorrhagic stroke [1]. |
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T80532 |
Ac-AAVALLPAVLLALLAP-YVAD-CHO
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Caspase
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Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable inhibitor of caspase-1 exhibiting antitumor activity [1]. |
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T31370 |
Delparantag
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PMX60056,PMX-60056,PMX 60056 |
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Delparantag( PMX-60056) is a heparins antidote designed to restore coagulation. |
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T80536 |
Ac-AAVALLPAVLLALLAP-LEVD-CHO
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Caspase
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Ac-AAVALLPAVLLALLAP-LEVD-CHO is a cell-permeable inhibitor of caspase-4 that exhibits antitumor activity [1]. |
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T80551 |
Calpain inhibitor V
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Mu-Val-HPh-FMK |
Antibiotic
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Calpain Inhibitor V (Mu-Val-HPh-FMK) is a cell-permeable, irreversible calpain inhibitor with demonstrated anti-chlamydial activity [1]. |
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T82803 |
Butylparaben sodium
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Butyl parahydroxybenzoate sodium,Butyl 4-hydroxybenzoate sodium |
DNA/RNA Synthesis
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Butylparaben sodium significantly impacts the later phases of spermatogenesis in the testes by impairing hormonal regulation and/or RNA and protein synthesis [1]. |
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T72439 |
Calpain Inhibitor XI
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Calpain Inhibitor XI, a reversible covalent inhibitor of calpain-1, is utilized in the research of neurodegenerative disorders. |
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T15336 |
Fonadelpar
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NPS-005,SJP-0035 |
PPAR
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Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy. |
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T63391 |
Calpain Inhibitor-2
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Calpain Inhibitor-2 is a lipophilic calpain inhibitor, and they showed moderate to good anti-proliferative effects in vitro compared to melanoma cell lines (A-375 and B-16F1) and PC-3 prostate cancer cells. was able to i... |
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T63172 |
LPA5 antagonist 2
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LPA5 antagonist 2 (compound 65) is a highly water-soluble LPA5 antagonist that significantly reduces nociception.LPA5 antagonist 2 can be used to study inflammatory and neuropathic pain. |
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T63231 |
LPA5 antagonist 1
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LPA5 antagonist 1 is a selective and potent lysophosphatidic acid receptor 5 (LPA5) antagonist with an IC50 value of 32 nM. LPA5 antagonist 1 has high brain permeability and antinociceptive activity and can be used to st... |
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T126544 |
3-O-Acetylpadmatin
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3-O-Acetylpadmatin is a useful organic compound for research related to life sciences. The catalog number is T126544 and the CAS number is 100595-93-5. |
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T63708 |
Calpain-2-IN-1
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Calpain-2-IN-1 is a selective calpain-2 inhibitor that prolongs ERK activation and thus enhances learning and memory. |
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T12876 |
Seladelpar sodium salt
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RWJ-800025 sodium salt,MBX-8025 sodium salt |
Others
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Seladelpar sodium salt (MBX-8025) is an orally active, effective and specific PPARδ agonist with an EC 50 of 2 nM which exhibiting more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respecti... |
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T77157 |
Dilpacimab
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Dilpacimab (ABT165), a potent dual-variable domain immunoglobulin, targets both the delta-like ligand 4 (DLL4) and VEGF pathways. It has potential applications in cancer research [1]. |
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TP2380 |
Elpamotide
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Elpamotide is a vaccine consisting of a VEGFR2-169 peptide. |
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TP2056 |
Acetyl-Calpastatin(184-210)(human)
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Acetyl-Calpastatin (184-210) (human) |
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Selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 μM). Increases secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio. |
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T80537 |
Ac-AAVALLPAVLLALLAP-LEHD-CHO
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Caspase
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Ac-AAVALLPAVLLALLAP-LEHD-CHO is a caspase inhibitor targeting caspases 4, 5, and 9, demonstrating protective effects in MCF-7 cells treated with Neocarzinostatin [1]. |
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T26182 |
Seladelpar lysine
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MBX-8025 lysine dihydrate,MBX-8025 Lysine,MBX 8025 Lysine MBX8025 Lysine |
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Seladelpar lysine, a selective PPAR-δ agonist, is used for the therapy of Homozygous Familial Hypercholesterolemia (HoFH). |
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T126550 |
1-O-β-D-Glucopyranosylpaeonisuffrone
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1-O-β-D-Glucopyranosylpaeonisuffrone is a useful organic compound for research related to life sciences and the catalog number is T126550. |
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T75158 |
Olpasiran
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Olpasiran is a small interfering RNA that reduces lipoprotein(a) synthesis in the liver. |
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T124098 |
12a-Hydroxydalpanol
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12a-Hydroxydalpanol is a useful organic compound for research related to life sciences. The catalog number is T124098 and the CAS number is 85042-77-9. |
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T125997 |
17-Methylparsonsianidine
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17-Methylparsonsianidine is a useful organic compound for research related to life sciences and the catalog number is T125997. |
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T33793 |
Olpadronic acid
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Me2 APD,Me2-APD,Me2APD |
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Olpadronic acid is a biochemical. |
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T25076 |
Amelparib
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JPI289,JPI-289,JPI 289 |
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Amelparib (JPI-289) is an inhibitor of the poly-ADP-ribose polymerase. |
