|
T24928 |
UPR-IN-17#
|
UPR inhibitor-17#,UPR IN 17#,UPR inhibitor 17# |
|
|
UPR-IN-17# is an effective pan-inhibitor of the unfolded protein response. |
|
T9110 |
Ceapin-A7
|
|
Others
|
|
Ceapin-A7, with an IC50 of 0.59 μM, selectively inhibits ATF6α signaling in response to ER stress. This compound is instrumental in investigating ATF6α's activation mechanism and its function in pathological conditions. |
|
T6854 |
GSK621
|
|
Apoptosis
,
AMPK
,
Autophagy
|
|
GSK621 is a specific and potent AMPK activator. |
|
T9349 |
IXA4
|
|
IRE1
|
|
IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1. IXA4-stimulated IRE1 activation also enhanced pancreatic function. |
|
T60191 |
Cuprous iodide
|
Iodocopper,Copper (I) iodide |
Antibiotic
|
|
Cuprous iodide (Iodocopper) is a antibiotic agent. |
|
T0448 |
(S)-(+)-Ibuprofen
|
Dexibuprofen,(S)-Ibuprofen |
BCL
,
Thrombin
,
Cysteine Protease
,
COX
,
PPAR
|
|
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX). |
|
T29069 |
Uprifosbuvir
|
MK3682,IDX21437,IDX 21437,MK 3682,IDX-21437,MK-3682 |
|
|
Uprifosbuvir is an inhibitor of uridine nucleotide analog HCV NS5B polymerase. |
|
T28886 |
Suprafenacine
|
N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide |
Microtubule Associated
|
|
Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine ... |
|
T27572 |
Ibuprofen diethylaminoethyl ester
|
Brufen diethylaminoethyl ester,BF-DEAE,BF DEAE |
Others
|
|
Ibuprofen diethylaminoethyl ester (BF DEAE) has anti-inflammatory activity, acts as a local anaesthetic and can be used in the study of neurological disorders. |
|
T0302 |
Triflupromazine hydrochloride
|
Neoprin,Fluopromazine hydrochloride,Fluorofen,Flumazin |
Dopamine Receptor
,
5-HT Receptor
,
AChR
,
Autophagy
|
|
Triflupromazine hydrochloride (Fluopromazine hydrochloride), an antipsychotic medication, is Dopamine D1/D2 receptor antagonists. |
|
T9047 |
Fluprednisolone
|
NSC-47439,NSC 47439,NSC47439 |
Others
|
|
Fluprednisolone (NSC-47439) is a synthetic glucocorticoid that has anti-inflammatory properties. |
|
T6687 |
Suprofen
|
Maldocil,Suprol,TN-762,Profenal |
COX
,
PGE Synthase
|
|
Suprofen (Suprol) is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. |
|
T0378 |
Oxybuprocaine hydrochloride
|
Risedronic Acid,Oxybuprocaine HCl |
Sodium Channel
|
|
Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology. |
|
T17309 |
(R)-(-)-Ibuprofen
|
levibuprofen,(R)-Ibuprofen |
NF-κB
|
|
(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation. (R)-(-)-Ibuprofen has anti-inflammatory and antinociceptive effects. |
|
T60707 |
Quinupramine
|
|
|
|
Quinupramine is an orally active antidepressant that shows antidepressant activity associated with the central serotonin system, but not with the β-adrenergic system. Quinupramine is able to penetrate into the CNS and af... |
|
T68093 |
Lobuprofen
|
|
COX
|
|
Lobuprofen is a small molecule COX inhibitor that is used to treat neurological disorders. |
|
T65013 |
Cuprizone
|
|
Others
|
|
Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response. |
|
T6472 |
Difluprednate
|
Myser,Epitopic,CM 9155 |
Others
|
|
Difluprednate (Myser)(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain. |
|
T1394 |
Ibuprofen
|
Brufen,(±)-Ibuprofe,Motrin,Advil |
COX
|
|
Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu... |
|
T8580 |
Bupranolol
|
|
Adrenergic Receptor
|
|
Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic. |
|
T3496 |
Buprofezin
|
NNI 750,Applaud,Buprofezine |
Reactive Oxygen Species
|
|
Buprofezin (Applaud) is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops. |
|
T40417 |
Ethylhydrocupreine hydrochloride
|
Optochin hydrochloride |
Antibacterial
,
Parasite
|
|
Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a derivative of quinine with antimicrobial activity against Streptococcus pneumoniae.Ethylhydrocupreine hydrochloride has antimalarial activity with an IC50 of... |
|
T12607 |
Quinupristin
|
|
Antibacterial
,
Antibiotic
|
|
Quinupristin is a member of the macrolide-lincosamide-streptogramin class of antibiotics. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete... |
|
T21193 |
Isoflupredone Acetate
|
|
Others
|
|
Isoflupredone Acetate is a corticosteroid with the activity of topical anti-inflammatory. |
|
T7363 |
Ibuprofen Piconol
|
U75630 |
Others
|
|
Ibuprofen Piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.Ibuprofen piconol is a Pyridyl ester of ibuprofen. |
|
T41303 |
Isoflupredone
|
Delta-Fluorocortisone,Isoflupredona,Isoflupredonum,9-Fluoroprednisolone |
Others
|
|
Isoflupredone (Isoflupredonum) is a synthetic corticosteroid that acts in vivo by binding to glucocorticoid and corticosteroid receptors in animals (such as horses) to inhibit inflammatory cells and inhibit the expressio... |
|
T27288 |
Esuprone
|
LU-43839,LU 43839,LU43839 |
MAO
|
|
Esuprone (LU-43839) is a novel reversible and highly selective MAO-A inhibitor with anticonvulsant activity for the treatment of depression. |
|
T16724 |
Razuprotafib
|
AKB-9778 |
Phosphatase
,
Others
|
|
Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ß (HPTPß) inhibitor (IC50: 50 nM). Razuprotafib is effective for the activation of Tie-2 and is protective against acute kidney injury. |
|
T6849 |
Uprosertib
|
GSK2141795,GSK795 |
Akt
|
|
Uprosertib (GSK2141795) (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2. |
|
T0324 |
Isoxsuprine hydrochloride
|
Duvadilan,Isolait |
Adrenergic Receptor
,
iGluR
|
|
Isoxsuprine hydrochloride (Isolait) is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. |
|
T21224 |
(+)-Fluprostenol
|
Fluprostenol, (+)-,Travoprost acid,AL-5848 |
Prostaglandin Receptor
|
|
(+)-Fluprostenol (AL-5848), an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal glycoprotein 1 (OVGP1). |
|
T6540 |
Ibuprofen Lysine
|
Neoprofen |
COX
|
|
Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug. |
|
T15428 |
Uprosertib hydrochloride
|
GSK2141795 (hydrochloride) |
Others
|
|
Uprosertib hydrochloride is a potent and selective inhibitor of pan-Akt (IC50: 180/328/38 nM for Akt1/Akt2/Akt3, respectively). |
|
T32978 |
Luprostiol
|
Reprodin,Equestrolin,Prosolvin |
|
|
Luprostiol is a prostaglandin analog. |
|
T31111 |
Cupric sebacate
|
|
|
|
Cupric sebacate is a biochemical. |
|
T75275 |
Quinupristin mesylate
|
|
|
|
Quinupristin mesylate, a streptogramin antibiotic, inhibits peptide bond formation, thereby halting the extension of polypeptide chains and facilitating the release of incomplete protein chains from bacterial ribosomal s... |
|
TP2285 |
Quinupristin-Dalfopristin Complex (mesylate)
|
|
Others
|
|
Quinupristin-Dalfopristin Complex is a mixture of two streptogramin antibiotics. Quinupristin-dalfopristin complex is a mixture of two streptogramin antibiotics, dalfopristin, and quinupristin. Streptogramin antibiotics ... |
|
T32684 |
Leuprolide (1-3)
|
Leuprorelin |
|
|
Leuprolide (1-3) is a manufactured version of a hormone used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, and early puberty. |
|
T69303 |
Isoxsuprine Free Base
|
|
|
|
Isoxsuprine Free Base is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplyi... |
|
T25431 |
Fluproquazone
|
Tormosyl,46 790,46-790 |
|
|
Fluproquazone is a quinazolinone derivative with potent antipyretic, analgesic, and anti-inflammatory effects. However, it was withdrawn during development due to liver toxicity. |
|
T71834 |
Ibuprofen ethyl ester
|
|
|
|
Ibuprofen ethyl ester is a derivative of Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) that is known to inhibit PGH synthase-1 and PGH synthase-2. |
|
T0302L |
Triflupromazine
|
Vesprin,Fluopromazine,Trifluopromazine,Adazine,Siquil |
|
|
Triflupromazine is a phenothiazine drug used as an antipsychotic and antiemetic. |
|
T40537 |
Ibuprofen Impurity K
|
|
|
|
Ibuprofen Impurity K is a compound that serves as an impurity in Ibuprofen. Ibuprofen itself is an anti-inflammatory inhibitor specifically designed to target COX-1 and COX-2. It exhibits inhibitory activity with IC50 va... |
|
T60292 |
Ibuprofen sodium
|
|
|
|
Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective inhibitor of COX-1 (IC 50 = 13 μM). Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroid... |
|
T72532 |
Ethylhydrocupreine
|
Optochin |
|
|
Ethylhydrocupreine (Optochin), a quinine derivative, exhibits antimicrobial properties against S. pneumoniae and antimalarial capabilities targeting Plasmodium falciparum with an IC50 of 25.75 nM. Additionally, it acts a... |
|
TP1473 |
Velmupressin
|
c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 |
|
|
c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 is a selective and short-acting peptidic V2 receptor (V2R) agonist with EC50s of 0.07nM and 0.02 nM for hV2R and rV2R, respectively. |
|
TP1205 |
Velmupressin acetate
|
V2 receptor (V2R) agonist,c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 acetate |
|
|
c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 acetate is a potent, selective and short-acting peptidic V2 receptor (V2R) agonist with EC50s of 0.07 and 0.02 nM for hV2R and rV2R, respectively. |
|
T37613 |
Ibuprofen Carboxylic Acid
|
|
|
|
Ibuprofen carboxylic acid is a major metabolite of ibuprofen . It prevents fructose-, cyanate-, and prednisolone-induced inactivation of catalase and fructose- and cyanate-induced inactivation of fumarase when used at a ... |
|
T37956 |
Tafluprost ethyl amide
|
|
|
|
Tafluprost ethyl amide is a prostaglandin derivative. Tafluprost ethyl amide reduces intraocular pressure (IOP) and affects eyelash growth. Tafluprost ethyl amide can be used in anti-glaucoma eye drops and cosmetics. |
|
T11605 |
(-)-Ibuprofenamide
|
(R)-Ibuprofenamide |
COX
|
|
(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity. |
