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Search Results for " acetylcholinesterase "

156

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T76130	Acetylcholinesterase
	Acetylcholinesterase (ACHE; EC 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses, and is often used in biochemical research. Acetylcholinesterase catalyzes th...
T1635	Fenchlorphos	Ronnel,Dermafos	AChE , Parasite
	Fenchlorphos (Dermafos) is a cholinesterase inhibitor, used as an insecticide.		AChE , Parasite
T4478	CID 16020046	C390-0219	Cannabinoid Receptor
	CID 16020046 (C390-0219) is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast.		Cannabinoid Receptor
T20539	Pirimiphos-methyl	R 33986,AI3-27699,Caswell No. 334B,PP511,Actelic	AChE , Parasite
	Pirimiphos-methyl (AI3-27699) is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, moths, sn...		AChE , Parasite
T25944	Phenoxyacetone	NSC-1876,NSC 1876,NSC1876	Others
	Phenoxyacetone (NSC-1876) is an inhibitor of acetylcholinesterase.		Others
T28226	Octahydroaminoacridine succinate		Others
	Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.		Others
T77352	ACHE Inhibitor 12
	ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.
T62360	AChE-IN-26		AChE
	AChE-IN-26 (compound 4a) is an AChE (acetylcholinesterase) inhibitor (IC50: 0.42 μM).		AChE
T1111	Pralidoxime Chloride	2-PAM chloride,2-Pyridinealdoxime methochloride,2-PAM (chloride)	AChE
	Pralidoxime Chloride (2-PAM chloride) is a useful agent in the treatment of organophosphate poisoning. Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, used to combat poisoning by organophosphates o...		AChE
T80671	ACHE-IN-38	5,6-Dimethoxy-2-(piperidin-4-yl)methylene-indan-1-one	Antifungal
	ACHE-IN-38 is a potent Acetylcholinesterase inhibitor that can be used for the synthesis of compounds with anti-inflammatory, anti-tumor, and antibacterial activities.		Antifungal
T23131	PE 154		AChE
	PE 154 is a potent fluorescent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 280 pM and 16 nM respectively. PE 154 is commonly used to label β-amyloid plaques in histochemical an...		AChE
Fr12799	AChE-IN-23
	AChE-IN-23 (compound 3h) is an inhibitor of acetylcholinesterase (AChE) with an IC 50 value of 48.3 μM [1].
T9355	2-Thiomorpholinoethanol		Others
	2-Thiomorpholinoethanol is a morpholine derivative that affects the nervous system by inhibiting the enzyme acetylcholinesterase (AChE) and increasing the amount of acetylcholine in the body.		Others
T7500	Isoxazole	1,2-oxazole	AChR
	Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.		AChR
T8907	Minaprine dihydrochloride		MAO , Monoamine Oxidase
	Minaprine dihydrochloride is a reversible MAO-A inhibitor; It weakly inhibit acetylcholinesterase. Minaprine dihydrochloride is an antidepressant for treatment of depression.		MAO , Monoamine Oxidase
T4466	Pitofenone hydrochloride	Baralgin Ketone Hydrochloride,Pitophenone hydrochloride	AChE
	Pitofenone hydrochloride (Pitophenone hydrochloride), a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively.		AChE
T4174	NSC 191412		Others
	NSC 191412 interacts with a variety of enzymes and receptors, including acetylcholinesterase and receptors for the neurotransmitter dopamine, and is an agonist or activator of these enzymes and receptors.		Others
T4631	NSC 4810		Others
	NSC 4810 is an amide bioactive compound that has been used as a substrate for cytochrome P450 enzymes in vivo and as a substrate for acetylcholinesterase in vitro.		Others
T1612	Neostigmine methyl sulfate	Normastigmin,Hodostin,Syntostigmin	AChR , AChE
	Neostigmine methyl sulfate (Syntostigmin) is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier, used in the treatment of myasthenia gravis.		AChR , AChE
T68084	Icopezil		AChE
	Icopezil is a small molecule acetylcholinesterase in (AChE) inhibitor for the treatment of neurological disorders and can be used in the study of Alzheimer's disease.		AChE
T8631	Pyridostigmine	Regonol,Mestinon-SR,UNII-19QM69HH21,PyridostigmineBromine,Pyridostigminum	Others
	Pyridostigmine(Regonol) is an acetylcholinesterase inhibitor that can treat myasthenia gravis by increasing acetylcholine at the postsynaptic motor endplate.		Others
T7041	Donepezil	E2020,Donepezilo,Aricept	AChE
	Donepezil (Aricept) is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to moderate dementia of the Alzheimer's type.		AChE
T1345	1,1-Bis(Methylthio)-2-Nitroethylene		Others
	1,1-Bis(Methylthio)-2-Nitroethylene (1,1-BMNE) has a variety of biochemical and physiological effects. It inhibits the activity of enzymes involved in the metabolism of drugs and other compounds, such as cytochrome P450 ...		Others
T19084	1-Naphthyl acetate		AChE
	1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages. 1-Naphthyl acetate is a potent chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity....		AChE
T83616	SEW06622		BACE , AChE
	SEW06622 is a potent inhibitor of acetylcholinesterase (AChE) and beta-secretase-1 (BACE-1) and is a potential candidate for the treatment of Alzheimer's disease.		BACE , AChE
T14194	β-NETA	α-NETA	AChE
	β-NETA (α-NETA) is a stable, noncompetitive, slowly reversible choline acetyltransferase (ChAT) inhibitor with an IC50 of 9 μM and is a potent chemokine-like receptor-1 (CMKLR1) antagonist. β-NETA has anti-cancer activit...		AChE
T60739L	Y13g dihydrochloride	Y13g 2HCl(T60739 Free base)	IL Receptor , AChE
	Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are related). Y13g dihydrochloride reverses STZ-induced memory defi...		IL Receptor , AChE
T50064	2-(4-methoxyphenyl)-2-oxoethyl 2-hydroxy-5-methylbenzoate		KLF
	2-(4-methoxyphenyl)-2-oxoethyl 2-hydroxy-5-methylbenzoate is a pro-neurotropic drug used to enhance cognitive function by increasing the synthesis and release of acetylcholine in the brain as well as by inhibiting the br...		KLF
T50041	N-(4-methoxyphenyl)prop-2-enamide	N-(4-Methoxyphenyl)acrylamide	Others
	N-(4-methoxyphenyl)prop-2-enamide (N-(4-Methoxyphenyl)acrylamide) is an acrylamide analog used as a molecular structural unit. It inhibits the enzyme acetylcholinesterase, increasing acetylcholine levels in the synaptic ...		Others
T1682	Methacholine Chloride	Mecholyl chloride,Acetyl-β-methylcholine chloride	AChR
	Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower r...		AChR
T2319	Acotiamide monohydrochloride trihydrate	Acotiamide hydrochloride,YM-443 HCl,Z-338 HCl	AChE
	Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamid...		AChE
T70236	Isonitrosoacetone
	Isonitrosoacetone is an acetylcholinesterase reactivator.
T70572	CHF-2060
	CHF-2060 is a novel acetylcholinesterase inhibitor.
T69233	Ganstigmine
	Ganstigmine is an acetylcholinesterase inhibitor for Alzheimer's disease.
T71258	Dehydrodeoxy donepezil
	Dehydrodeoxy donepezil is an inhibitor of acetylcholinesterase (AChE)
T26597	Allyxycarb	Hydrol
	Allyxycarb is an acetylcholinesterase inhibitor.
T28041	Mimopezil	ZT-1 LA,Debio-9902-SR,Debio-9902,ZT-1
	Mimopezil is an acetylcholinesterase (AChE) inhibitor.
T69289	BW284C51
	BW284C51 is a selective acetylcholinesterase inhibitor. It is also a nicotinic antagonist
T27105	Cyclophostin
	Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).
T70714	(-)-Donepezil
	(-)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase.
T70697	(+)-Donepezil
	(+)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase.
T69131	Pitofenone
	Pitofenone is an inhibitor of the acetylcholinesterase activity from bovine erythrocytes and electric eel.
T70474	Gallamine
	Gallamine is an allosteric antagonist at muscarinic M2 acetylcholine receptors and an inhibitor of acetylcholinesterase.
T21219	Isatin-O	Isatin-3-oxime
	Isatin-O acts as a neutral BBB crossing reactivator for acetylcholinesterase inhibited by paraoxon and is also an anticonvulsant.
T19810	Pirimicarb
	Pirimicarb is an insecticide that inhibits acetylcholinesterase in selective species.
T71780	Diisopropylamine dichloroacetate
	Diisopropylamine dichloroacetate stimulates smooth muscle & strongly inhibits acetylcholinesterase activity.
T70973	Zifrosilone
	Zifrosilone is an acetylcholinesterase inhibitor.
T70117	Cyclanoline (free base)
	Cyclanoline (free base) is an acetylcholinesterase inhibitor
T20940	Chlorpyrifos-methyl	M-3196,M 3196
	Chlorpyrifos-methyl inhibits acetylcholinesterase by acting on the nervous system of insects.
T69510	BDB-108
	BDB-108 is a re-activator of isopropyl-methylphosphonylated acetylcholinesterase.

Compounds

Acetylcholinesterase

Synonym: Ronnel,Dermafos

Target: AChE, Parasite

CID 16020046

T4478

Synonym: C390-0219

Target: Cannabinoid Receptor

Pirimiphos-methyl

T20539

Synonym: R 33986,AI3-27699,Caswell No. 334B,PP511,Actelic

Target: AChE, Parasite

Phenoxyacetone

T25944

Synonym: NSC-1876,NSC 1876,NSC1876

Target: Others

Octahydroaminoacridine succinate

Synonym: 2-PAM chloride,2-Pyridinealdoxime methochloride,2-PAM (chloride)

Target: AChE

ACHE-IN-38

T80671

Synonym: 5,6-Dimethoxy-2-(piperidin-4-yl)methylene-indan-1-one

2-Thiomorpholinoethanol

Minaprine dihydrochloride

T8907

Synonym:

Target: MAO, Monoamine Oxidase

Pitofenone hydrochloride

T4466

Synonym: Baralgin Ketone Hydrochloride,Pitophenone hydrochloride

Neostigmine methyl sulfate

T1612

Synonym: Normastigmin,Hodostin,Syntostigmin

Synonym: Regonol,Mestinon-SR,UNII-19QM69HH21,PyridostigmineBromine,Pyridostigminum

Target: Others

Donepezil

T7041

Synonym: E2020,Donepezilo,Aricept

Target: AChE

1,1-Bis(Methylthio)-2-Nitroethylene

Synonym: Y13g 2HCl(T60739 Free base)

Target: IL Receptor, AChE

2-(4-methoxyphenyl)-2-oxoethyl 2-hydroxy-5-methylbenzoate

T50064

Synonym:

Target: KLF

N-(4-methoxyphenyl)prop-2-enamide

T50041

Synonym: N-(4-Methoxyphenyl)acrylamide

Target: Others

Methacholine Chloride

T1682

Synonym: Mecholyl chloride,Acetyl-β-methylcholine chloride

Target: AChR

Acotiamide monohydrochloride trihydrate

T2319

Synonym: Acotiamide hydrochloride,YM-443 HCl,Z-338 HCl

Dehydrodeoxy donepezil

Synonym: ZT-1 LA,Debio-9902-SR,Debio-9902,ZT-1

Synonym: Isatin-3-oxime

Diisopropylamine dichloroacetate

Cyclanoline (free base)

Synonym: M-3196,M 3196

カタログ番号	製品名	別名	ターゲット
TN1899	Lycoramine		AChE
	Lycoramine is a natural product isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor		AChE
Fr14127	Coumaran	2,3-Dihydrobenzofuran	Endogenous Metabolite , AChE
	Coumaran (2,3-Dihydrobenzofuran) is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Coumaran(2,3-Dihydrobenzofuran) can be used as a biopesticide. 2,3-dihydrobenzofuran is a member of the clas...		Endogenous Metabolite , AChE
TN6786	O-Desmethyl Galanthamine	Sanguinine	AChE
	O-Desmethyl Galanthamine (Sanguinine) is galanthamine-type alkaloid and it is an acetylcholinesterase (AChE) inhibitor, with an IC50 1.83 μM.		AChE
T6S0653	Linarin	Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine	TNF , AChE
	1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediat...		TNF , AChE
T0086	Galanthamine hydrobromide	Galantamine hydrobromide,Galanthamine HBr	AChR , AChE
	Galanthamine hydrobromide (Galantamine hydrobromide), a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors.		AChR , AChE
T2S1200	Sinapine		Antioxidant , P-gp , AChE
	1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant and radio-protective activities.		Antioxidant , P-gp , AChE
T3392	Sinapine thiocyanate		P-gp , AChE
	Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds. It is the choline ester of Sinapic Acid (S486800). It is also a phenolic-chloine conjugates, acting as anti-o...		P-gp , AChE
T4852	Trimyristin	Trimyristoylglycerol,Tritetradecanoin,Glyceryl trimyristate,1,2,3-Tritetradecanoylglycerol	Phosphatase , Endogenous Metabolite , AChE
	Trimyristin (Tritetradecanoin) is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging from yeast to humans. In humans, glyceryl trimyristate is i...		Phosphatase , Endogenous Metabolite , AChE
TN2298	Vincosamide		AChE
	Vincosamide is an alkaloid from Psychotria leiocarpa extract, inhibits the acetylcholinesterase (AChE) activity with anti-inflammatory activity. Vincosamide can effect relaxation of the supercoiled pBR322 plasmid DNA in ...		AChE
T6S2356	Corynoline	(+)-Corynoline	Nrf2 , AChE
	1. Corynoline ((+)-Corynoline) is an acetylcholinesterase inhibitor.		Nrf2 , AChE
T4S1725	Galanthamine	Galantamine	Apoptosis , AChE
	Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.		Apoptosis , AChE
TN1091	Dehydronuciferine		AChE
	Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn. Dehydronuciferine shows inhibitory of acetylcholinesterase with the IC50 of 25 ug/mL.		AChE
TN1589	Dihydrowithaferin A		AChE
	Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prevent or decrease the growth of tumors.		AChE
T2846	Isoimperatorin		Antibacterial , AChE
	Isoimperatorin is an anti-inflammatory agent, exhibits significant inhibitory effects on acetylcholinesterase (AChE).		Antibacterial , AChE
TN1305	Ethoxysanguinarine	6-Ethoxydihydrosanguinarine	Apoptosis , AChR
	Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) shows human blood acetylcholinesterase (HuAChE) and human plasma butyrylcholinesterase (HuBuChE) inhibitory activity, with IC50 values of 0.83 +/- 0.04 microM and 4.20 +/-...		Apoptosis , AChR
TN6919	Methyl tridecanoate		Beta Amyloid , AChE
	Methyl tridecanoate is a natural product.		Beta Amyloid , AChE
T2984	Scopoletin	Chrysatropic acid,Esculetin 6-methyl ether,Gelseminic acid,6-Methylesculetin	Apoptosis , AChR , AChE
	Scopoletin (Esculetin 6-methyl ether) is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).		Apoptosis , AChR , AChE
T9862	Pseudocoptisine chloride	Isocoptisine chloride	AChE
	Pseudocoptisine chloride (Isocoptisine chloride) is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity (IC50 = 12.8 μ...		AChE
T5855	Edrophonium chloride		AChE
	Edrophonium chloride is an acetylcholinesterase (AChE) inhibitor that is known to prevent the breakdown of the neurotransmitter acetylcholine by binding specifically to its catalytic site.		AChE
T13301	Violanthin		AChE
	Violanthin is a natural product isolated from the aerial parts of Piper bavinum and inhibits acetylcholinesterase (AChE) (IC50: 79.80 μM). It has potent antioxidant and antibacterial activities.		AChE
T3819	Ursolic acid acetate	Acetylursolic acid,3-Acetylursolic Acid	AChE
	Ursolic acid acetate (Acetylursolic acid) has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO production inhibitory activities. Acetylursolic acid has inhibition ...		AChE
TN1124	Neoeriocitrin		AChE
	Neoeriocitrin is a natural product isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor.		AChE
TN4368	Kaempferol-3,7-di-O-β-glucoside	Kaempferol 3,7-di-O-glucoside	Glucosidase , Amylase
	Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) is a flavonol from Morettia philaena, It can inhibit α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3, 7-di-o-β-Glucoside has neuroprotective ac...		Glucosidase , Amylase
T9076	Spinosad		Others
	Spinosad is a naturally-occurring insecticide found in the the soil bacterium S. spinosa. It is a mixture of the macrocyclic lactones spinosyn A and spinosyn D, which act as agonists of insect nicotinic acetylcholinester...		Others
TN1030	N-p-trans-Coumaroyltyramine		AChE , Parasite
	N-p-trans-Coumaroyltyramine is a natural product, is an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122 μM. N-p-trans-Coumaroyltyramine exhibits anti-trypanosomal activity with an IC50 of 13.3 μM for T. bruc...		AChE , Parasite
TN2230	Soyasaponin Ba		Others
	Soyasaponin Ba may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects.Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without ...		Others
T11351	Galanthamine N-Oxide		AChE
	Galanthamine N-Oxide, an alkaloid extracted from Zephyranthes concolor bulbs, effectively inhibits acetylcholinesterase (AChE) from electric eel with an EC50 of 26.2 μM. It acts as a significant inhibitor of substrate ac...		AChE
TN3466	Atherosperminine		cAMP , Calcium Channel , AChR , Parasite
	Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine shows strong anti-plasmodial activity against Plasmodium falciparum, with t...		cAMP , Calcium Channel , AChR , Parasite
T2S1635	3-Isomangostin		MTH1
	3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac...		MTH1
T3767	Polygalacic acid	Virgaureagenin G	MMP , AChR , AChE
	Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and eleva...		MMP , AChR , AChE
T5S2360	Corydaline	Corydalin,(+)-Corydaline	P450 , Virus Protease , Opioid Receptor , AChE
	1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr...		P450 , Virus Protease , Opioid Receptor , AChE
T3026	(-)-Huperzine A	HupA,Huperzine A	Apoptosis , AChR , AChE , iGluR
	(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the tr...		Apoptosis , AChR , AChE , iGluR
T5S2254	Swertianolin	Bellidifolin-8-O-Glucoside	Others , HBV , Antibacterial , AChE
	1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. Swertianolin...		Others , HBV , Antibacterial , AChE
T2S1792	Lycobetaine	Ungeremine	Antibacterial
	1. Lycobetaine (Ungeremine) is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.2. Lycobetaine have strong antibacterial activity against Flavobacterium columnare . 3. Lycobetaine effectively...		Antibacterial
T3S1612	Kuwanon G	Moracenin B,Kuwanone G	Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase
	1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a...
TN5940	Lycoclavanol	14-Serratene-3,21,24-triol
	Lycoclavanol exhibits acetylcholinesterase inhibition activity.
TN6009	Pseudopalmatine
	Pseudopalmatine exhibits antiplasmodial activity. It also shows anti-acetylcholinesterase (AChE) activity, with IC50 values of 1.8uM.
T27104	Cyclopenin	NSC 114538,NSC-114538,NSC604989,NSC 604989,NSC-604989,NSC114538
	Cyclopenin is an inhibitor of acetylcholinesterase (AChE; IC50 = 2.04 μM for human recombinant AChE).
T75455	Paecilomide
	Paecilomide is a pyridone alkaloid and acetylcholinesterase inhibitor [1] .
TN1559	Dehydrodicentrine		AChR
	Dehydrodicentrine showed strong acetylcholinesterase (AChE) inhibitory effects with the IC50 value of 2.98 μM.		AChR
T21438	Physostigmine	Physostol,Antilirium,Eserine,Esromiotin,Ezerin
	Physostigmine is a potent and reversible inhibitor of cholinesterase. It is also reported to form a slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE).
TN6050	Macusine B
	Macusine B is a dual inhibitor, has almost equal inhibitory activity on both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).
T72794	Millmerranone A
	Millmerranone A shows the acetylcholinesterase inhibitory property.
T40512	Echimidine N-oxide
	Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.
TN3570	Calyxamine B		Others
	Calyxamine B has inhibitory activity on acetylcholinesterase, the effect is comparable to the natural inhibitors.		Others
TN2505	1,5-Diphenylpentan-1-one		AChR
	1,5-Diphenylpentan-1-one shows poor insecticidal and acetylcholinesterase inhibitory activities.		AChR
TN1561	Dehydroglaucine		Antifection
	Dehydroglaucine is an acetylcholinesterase inhibitor, it shows antimicrobial activity against Staphylococcus aureus, Mycobacterium smegmatis, Candida albicans, and Aspergillus niger.		Antifection
TN1409	Asimilobine		AChR , Antifection
	(-)-Asimilobine shows antioxidative, anti-acetylcholinesterase (AChE), anti-α±-glucosidase, anti-leishmanial and anti-fungal activities; it displays weak inhibition against Streptococcus mutans (ATCC 25175), with a minim...		AChR , Antifection
TN3875	Dipterocarpol		P450 , AChR
	Dipterocarpol is a dammarane-type triterpenoid, as are the major bioactive compounds of ginseng. Dipterocarpol A shows moderate acetylcholinesterase inhibitory activity with the IC50 value of 8.28 uM.		P450 , AChR
T28122	Myrtenal	NSC-54384,NSC 54384,NSC54384,Benihinal
	Myrtenal is a natural monoterpene. It is found to attenuate diethylnitrosamine-induced hepatocellular carcinoma in rats by stabilizing intrinsic antioxidants and modulating apoptotic and anti-apoptotic cascades. Myrtenal...
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天然物製品

Synonym: 2,3-Dihydrobenzofuran

Target: Endogenous Metabolite, AChE

O-Desmethyl Galanthamine

Synonym: Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine

Target: TNF, AChE

Galanthamine hydrobromide

T0086

Synonym: Galantamine hydrobromide,Galanthamine HBr

Target: Antioxidant, P-gp, AChE

Synonym: Trimyristoylglycerol,Tritetradecanoin,Glyceryl trimyristate,1,2,3-Tritetradecanoylglycerol

Target: Phosphatase, Endogenous Metabolite, AChE

Synonym: (+)-Corynoline

Target: Apoptosis, AChE

Target: Antibacterial, AChE

Ethoxysanguinarine

TN1305

Synonym: 6-Ethoxydihydrosanguinarine

Target: Apoptosis, AChR

Methyl tridecanoate

TN6919

Synonym:

Target: Beta Amyloid, AChE

Scopoletin

T2984

Synonym: Chrysatropic acid,Esculetin 6-methyl ether,Gelseminic acid,6-Methylesculetin

Target: Apoptosis, AChR, AChE

Pseudocoptisine chloride

T9862

Synonym: Isocoptisine chloride

Synonym: Acetylursolic acid,3-Acetylursolic Acid

Kaempferol-3,7-di-O-β-glucoside

TN4368

Synonym: Kaempferol 3,7-di-O-glucoside

Target: Glucosidase, Amylase

N-p-trans-Coumaroyltyramine

TN1030

Synonym:

Target: AChE, Parasite

Target: cAMP, Calcium Channel, AChR, Parasite

Synonym: Virgaureagenin G

Target: MMP, AChR, AChE

Corydaline

T5S2360

Synonym: Corydalin,(+)-Corydaline

Target: P450, Virus Protease, Opioid Receptor, AChE

(-)-Huperzine A

T3026

Synonym: HupA,Huperzine A

Target: Apoptosis, AChR, AChE, iGluR

Swertianolin

T5S2254

Synonym: Bellidifolin-8-O-Glucoside

Target: Others, HBV, Antibacterial, AChE

Lycobetaine

T2S1792

Synonym: Ungeremine

Target: Antibacterial

kuwanon G

T3S1612

Synonym: Moracenin B,Kuwanone G

Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase

Lycoclavanol

TN5940

Synonym: 14-Serratene-3,21,24-triol

Synonym: NSC 114538,NSC-114538,NSC604989,NSC 604989,NSC-604989,NSC114538

Synonym: Physostol,Antilirium,Eserine,Esromiotin,Ezerin

1,5-Diphenylpentan-1-one

Target: AChR, Antifection

Synonym: NSC-54384,NSC 54384,NSC54384,Benihinal

Target:

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01742	Acetylcholinesterase Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Acetylcholinesterase, also known as ACHE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. Acetylcholinesterase plays a crucial role...
TMPH-03234	Acetylcholinesterase Protein, Rat, Recombinant (His)	Rat	E. coli
	Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
TMPJ-00695	CuTA Protein, Human, Recombinant (His)	Human	E. coli
	Protein CutA (CUTA) posseses a signal peptide and is widely expressed in brain. CUTA mayforms part of a complex of membrane proteins attached to acetylcholinesterase (AChE). CUTA takes part in cellular tolerance to a bro...
TMPY-01693	Butyrylcholinesterase Protein, Human, Recombinant (His)	Human	HEK293
	Butyrylcholinesterase (BCHE), also known as cholinesterase or BuChE, is an enzyme defined as "pseudo" or "non-neuronal" cholinesterase. Butyrylcholinesterase (BCHE) is widely distributed in the nervous system as well as ...
TMPY-01596	Butyrylcholinesterase Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Butyrylcholinesterase (BCHE), also known as cholinesterase or BuChE, is an enzyme defined as "pseudo" or "non-neuronal" cholinesterase. Butyrylcholinesterase (BCHE) is widely distributed in the nervous system as well as ...