59
10
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T13573 | Arrhythmias-Targeting Compound 1 | Others | |
Arrhythmias-Targeting Compound 1 is a compound. It is used in the research of arrhythmias. | |||
T8391 | Cesium chloride | CsCl | Potassium Channel |
Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth. | |||
T20898 | (R)-Propranolol hydrochloride | Dexpropranolol hydrochloride,(R)-(+)-Propranolol | Adrenergic Receptor |
(R)-Propranolol hydrochloride (Dexpropranolol hydrochloride) is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antag... | |||
T1496 | Amiodarone hydrochloride | Amiodar,Amiodarone HCl,Nexterone | Potassium Channel , Adrenergic Receptor , Autophagy |
Amiodarone hydrochloride (Amiodarone HCl) is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM C... | |||
T15207 | Eleclazine hydrochloride | GS 6615 hydrochloride | Sodium Channel |
Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM). | |||
T1320 | Disopyramide | Triombrin,Hypaque sodium,amidotrizoate sodium | Potassium Channel , Sodium Channel , AChR |
Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the h... | |||
T24021 | E 0747 | E 747,L 29065,E0747,E-0747 | Sodium Channel |
E 0747 (E0747) is a new antiarrhythmic compound that inhibits arrhythmias by inhibiting Na channels in cardiac cells. | |||
T7477 | Antazoline | Others | |
Antazoline has antihistamine and anticholinergic effects.It used to treat a variety of arrhythmias. | |||
T29050 | UK 66914 | UK66914,UK-66914 | Potassium Channel |
UK 66914 is a K(+) channel blocker for the study of cardiac arrhythmias. | |||
T7386 | Bretylium tosylate | Others | |
Bretylium tosylate is an inhibitor of the presynaptic release of vasoconstrictor neurotransmitters, a available antiarrhythmic drug for ventricular arrhythmias. | |||
T28686 | SB-237376 HCl | SB-237376 hydrochloride | Calcium Channel , Sodium Channel |
SB-237376 HCl (SB-237376 hydrochloride) is a calcium and potassium channel antagonist used in the treatment of cardiac arrhythmias. | |||
T7827 | Glycyrrhizinic acid, potassium salt | Others | |
Glycyrrhizinic acid, potassium salt can reduce ventricular arrhythmias caused by veratrol | |||
T30520 | BMS-394136 | BMS394136,BMS 394136,BMS394136;UNII-M694U7167K | Potassium Channel |
BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation. | |||
T28686L | SB-237376 | Calcium Channel , Sodium Channel | |
SB-237376 is a calcium and potassium channel antagonist used to treat cardiac arrhythmias. | |||
T27630 | Isbogrel | CV4151,CV-4151,CV 4151 | Prostaglandin Receptor |
Isbogrel (CV4151) is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor that can be used to study cardiac arrhythmias, transient ischemic attacks and thrombosis. | |||
T11239 | Ethacizine hydrochloride | NIK-244,Ethacizin,NIK-244 hydrochloride | Sodium Channel |
Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity, and its effects are related to cardiac activity and can be used to study arrhythmias and myocardial infarction. | |||
T28748 | Selodenoson | RG14202,DTI0009,DTI-0009,RG-14202,DT-009,DT009 | Adenosine Receptor |
Selodenoson (RG-14202) is a selective adenosine A1 receptor agonist used to slow the heart rate in patients with atrial fibrillation and to treat arrhythmias. | |||
T31213L | Dazmegrel HCl | UK-38,485 HCl,Dazmegrel HCl(76894-77-4 Free base) | Prostaglandin Receptor |
Dazmegrel HCl is a platelet thromboxane inhibitor used in the study of myocardial infarction and arrhythmias. | |||
T25701 | Levosemotiadil | SD 3212,SA 3212 | LDL , Calcium Channel |
Levosemotiadil(SA 3212) is a novel calcium antagonist and a very potent inhibitor of low-density lipoprotein oxidation.Levosemotiadil may be used to prevent lethal cardiac arrhythmias. | |||
T68038 | Celivarone | Potassium Channel | |
Celivarone is a potassium channel blocker used in the study of arrhythmias, atrial flutter and atrial fibrillation. | |||
T32155 | Indecainide | Ricainide,Ricainid,Decabid,Indecainidum,Indecainida | Others |
Indecainide (Ricainid) is a novel antiarrhythmic compound that is carcinogenic and can be used to study chronic stable ventricular arrhythmias secondary to coronary artery disease or cardiomyopathy. | |||
T6955 | Propafenone hydrochloride | Propafenone HCl,Arythmol,SA-79 (hydrochloride),Rytmonorm,Rythmol | Sodium Channel |
Propafenone hydrochloride (Arythmol8) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias. | |||
T23536 | Xamoterol hemifumarate | ICI 118587 hemifumarate,Corwin hemifumarate | Adrenergic Receptor |
Xamoterol hemifumarate is a potent and selective β1-adrenoceptor agonist.Xamoterol hemifumarate is a potential compound for the study of the relationship between cardiac arrhythmias and β1-adrenergic stimulation with IKr... | |||
T77550 | O-Desmethyl Quinidine | Others | |
O-Desmethyl Quinidine is a novel quinidine analog with significant antiarrhythmic activity and low acute toxicity that may be useful in the treatment of cardiac arrhythmias. | |||
T30586L | Brefonalol HCl | Brefonalol HCl(103880-26-8 Free base) | Adrenergic Receptor |
Brefonalol HCl is an ADRA antagonist used in the treatment of neurological disorders and cardiovascular diseases and can be used in the study of angina pectoris, arrhythmias and hypertension. | |||
T68164 | Tolamolol | Adrenergic Receptor | |
Tolamolol is a selective β-adrenergic blocker that significantly reduces the degree of exercise-induced inhibition of the S-T segment and can be used in the treatment of cardiac arrhythmias. | |||
T0112L | Diltiazem | Diltiazem free base,Dilticard,CRD-401,CRD401,Dilzen,CRD 401 | |
Diltiazem is a non-dihydropyridine (non-DHP) calcium channel blocker that relaxes the smooth muscle in arterial walls, thus opening (dilating) arteries, allowing easier blood flow, and lowering blood pressure, and is use... | |||
T83979 | Sulcardine 2HCl | Sulcardine 2HCl(343935-60-4 Free base),HBI-3000 2HCl | HER , Sodium Channel |
Sulcardine 2HCl is a multi-ion channel blocker with antiarrhythmic effects that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation and ventricular arrhythmias. | |||
T60322 | Procainamide | Biocoryl,Novocainamide | DNA Methyltransferase |
Procainamide (Novocainamide) is a specific and potent DNA methyltransferase 1 ( DNMT1 ) inhibitor. Procainamide is a Class 1A antiarrhythmic agent. Procainamide has the potential for the research of cancer and arrhythmia... | |||
T1282 | Carteolol hydrochloride | Arteoptic,Abbott-43326,OPC-1085 hydrochloride,Carteolol HCl,Mikelan | Adrenergic Receptor |
Carteolol hydrochloride (Abbott-43326) is a synthetic quinolinone derivative, antihypertensive Carteolol Hydrochloride is a nonselective beta-adrenoceptor blocking agent for beta-1 and beta-2 receptors with no membrane-s... | |||
T30251 | AZD-1305 | UNII-CZO834LXQM,AZD 1305 | Others |
AZD-1305 is a novel anti-arrhythmic compound that primarily blocks the fast component of IKr, l-type calcium currents and intra-ward sodium currents in mammalian cells and ventricular cardiomyocytes and can be used in st... | |||
T1012 | Acebutolol hydrochloride | Acebutolol HCl | Adrenergic Receptor |
Acebutolol hydrochloride (Acebutolol HCl) acts as a cardioselective beta-adrenergic antagonist with little effect on bronchial receptors and has intrinsic sympathomimetic properties. Acebutolol hydrochloride is the hydro... | |||
T20656 | Verapamil | NSC 135784,NSC-135784,CP-16533-1,(±)-Verapamil | P450 , Calcium Channel , P-gp |
Verapamil (CP-16533-1) is a non-dihydropyridine calcium channel blocker, a P-gp inhibitor, and a CYP3A4 inhibitor with oral activity. Verapamil can be used for the treatment of hypertension, angina pectoris, and myocardi... | |||
T0866 | Propafenone | Rythmol,Propafenonum | Potassium Channel , MRP , Sodium Channel |
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.... | |||
T40777 | Encainide | Encainide,MJ9067 | |
Encainide (MJ9067), a class IC antiarrhythmic drug, holds potential for research into life-threatening and symptomatic ventricular arrhythmias as well as supraventricular arrhythmias. | |||
T30551 | BN 52256 | BN52256,BN-52256 | |
BN 52256 helps reduce arrhythmias. | |||
T19887 | Teflurane | Abbott-16900,Tefluranum,Abbott 16900,Teflurano | |
Teflurane is a halocarbon drug, Teflurane was investigated as an inhalational anesthetic, a high incidence of cardiac arrhythmias in patients, similarly to the cases of halopropane and norflurane. | |||
T5336L | Zacopride | Racemic zacopride | |
Zacopride is a selective agonist of inward rectifier potassium current (I K1) channel, inhibiting ventricular arrhythmias without affecting atrial arrhythmias. | |||
T69472 | Edrophonium | ||
Edrophonium is a rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles. | |||
T26136 | RS 2135 | RS2135,RS-2135 | |
RS 2135 is a novel class I antiarrhythmic agent to inhibit ischemia-induced ventricular arrhythmias. | |||
T30861 | CH 200 | CH-200,CH200,06-14C | |
CH 200 is a novel antiarrhythmic drug that inhibits arrhythmias in beagles more effectively than procainamide and lidocaine. | |||
T28130 | Naltiazem | RO 236152,RO-236152,RO236152 | |
Naltiazem, a calcium channel antagonist, is used potentially for the treatment of arrhythmias, hypertension and myocardial infarction. | |||
T83102 | Antiarrhythmic peptide (cattle atrium) | ||
Antiarrhythmic peptide (cattle atrium), a hexapeptide, exhibits a protective effect against arrhythmias induced by experimental agents [1]. | |||
T23619 | Acodazole | NSC 305884,NSC305884,NSC-305884 | |
Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias. | |||
T63330 | Clamikalant sodium | ||
Clamikalant sodium is a non-selective, ATP-sensitive potassium (KATP) channel blocker that can be used to study cardiac arrhythmias. | |||
T72323 | Antiarrhythmic agent-1 | ||
Antiarrhythmic agent-1 (example I), functioning as an antiarrhythmic agent and an IKr potassium channel blocker (IC 50 <1 μM), effectively inhibits cardiac arrhythmias. | |||
T26875 | BN 50739 | BN50739,BN-50739 | |
BN 50739 is an antagonist of platelet-activating factor (PAF). BN 50739 suppresses certain cardiac arrhythmias. PAF is released from ischaemic myocardium and may contribute to initiation of ischaemia-induced ventricular ... | |||
T21373 | Aprindine hydrochloride | Fiboran,Amidonal,Aprinidine,Aprindin,Aprindine HCl,Aprindina,Fibocil | |
Aprindine HCl is a Class 1b antiarrhythmic agent used to manage ventricular and supraventricular arrhythmias. In one study, it delayed atrial fibrillation more than digoxin did. It has shown effectiveness when given oral... | |||
T1271 | Pronetalol | ||
Pronethalol ((±)-Pronethalol), a non-selective β-adrenergic antagonist, effectively inhibits Sox2 expression and offers protection against Digitalis-induced ventricular arrhythmias. Additionally, it can reverse such arrh... | |||
T31119 | CVT-2759 | UNII-42E8N8RC9Z,CVT2759 | |
CVT-2759 is A potential partial agonist for A(1)-ADORs, and it may be useful to slow atrioventricular node conduction to reduce ventricular rate without causing the atrioventricular block, bradycardia, atrial arrhythmias... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T41358 | 2-Hydroxybenzylamine | Others | |
2-Hydroxybenzylamine, a potent small molecule scavenger of IsoLGs, sequesters the reactive species as inert adducts. 2-Hydroxybenzylamine may be used to decrease early recurrence of atrial fibrillation and other atrial a... | |||
T8183 | Deslanoside | Desacetyllanatoside C,Deacetyllanatoside C | ATPase , Drug Metabolite |
Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane p... | |||
T5S1099 | Liensinine | Apoptosis , Mitophagy , Others , Autophagy | |
1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias. | |||
T5212 | Trilinolein | Glycerol trilinoleate,1,2,3-Trilinoleoylglycerol | Antioxidant , Endogenous Metabolite |
Trilinolein (1,2,3-Trilinoleoylglycerol) is a triacylglycerol and has been reported to provide a number of beneficial effects including reducing thrombogenicity and arrhythmias and increasing erythrocyte deformability. I... | |||
T5645 | Nerol | Cis-Geraniol,Neryl alcohol | Apoptosis , Reactive Oxygen Species , Mitochondrial Metabolism , Endogenous Metabolite , Antifungal |
Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian heart. | |||
T2973 | Astragaloside IV | AST-IV,AS-IV | MMP , ERK , Estrogen/progestogen Receptor , JNK |
Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cel... | |||
T2S2215 | Crebanine | Apoptosis , Others , Akt | |
1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rat... | |||
TMA0763 | Methyl 3,4,5-trimethoxycinnamate | Potassium Channel , Calcium Channel | |
Methyl 3,4,5-trimethoxycinnamate may protect the heart from arrhythmias via its inhibitory effect on calcium channel. | |||
TN1875 | Liriodenine | BCL , Caspase , p53 | |
Liriodenine is a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro, it has antitumor, antibacterial and antifungal activities, it can suppress ventricular arrhythmias induced by myocardial isch... | |||
TN4616 | N-Methyltaxol C | Others | |
N-methyltaxol C and paclitaxel can produce a positive inotropic effect in papillary muscle, without alterations in the action potential. They can induced conduction arrhythmias and reduce coronary flow and left ventricul... |