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天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T31976	Glymidine sodium		Others
	Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secretion.		Others
T17250	W-54011		ROS , Complement System
	W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and g...		ROS , Complement System
T16850	SB-265610	GSK-CXCR2	CXCR
	SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and...		CXCR
T29135	VU0422288	VU-0422288,ML-396,ML396,VU 0422288,ML 396	GluR
	VU0422288 (ML396) is a potent orthosteric modulator of type III mGlu receptors (mGlus).VU0422288 shows inhibition of mGluR4, mGluR7, and mGluR8 in a calcium mobilization assay.VU0422288 can be used to study Rett syndrome...		GluR
T23010	MNI 137		Others , GluR
	MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.		Others , GluR
T28073	MLS1547	MLS000051547,MLS 1547,MLS-1547	Dopamine Receptor
	MLS1547 (MLS000051547) is a highly efficacious agonist of G protein-biased dopamine D2 receptor with a Ki of 1.2 μM. MLS1547 stimulates D2R G protein-mediated signaling with EC50 of 0.37 μM in a calcium mobilization assa...		Dopamine Receptor
T13325	VU 0365114		AChR
	VU 0365114 is a positive allosteric modulator of mAChR M5 (EC50: 2.7 μM).		AChR
T2370	AC-55541	AOB2796	Proteasome , Protease-activated Receptor
	AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.		Proteasome , Protease-activated Receptor
T9466	RTICBM-189		Others
	RTICBM-189 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 (CB1) receptor with a pIC50 of 7.54 in Ca2+ mobilization assay. RTICBM-189 has pIC50s of 5.29 and 6.25 for hCB1 and mCB1, respectivel...		Others
TP1936L1	RFRP3(human) acetate(311309-27-0 free base)		Neuropeptide Y Receptor
	RFRP-3(human) acetate, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) acetate is a NPFF1 receptor agonist, it inhibits forskolin-induced produ...		Neuropeptide Y Receptor
T6764L	ATI-2341 acetate(1337878-62-2 free base)		CXCR
	ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13. ATI-2341 acetate activates inhibitory heterotrimeric G protein (GI) to promote the inhibition of cAMP production and induce ...		CXCR
T27753	KT-362 fumarate	KT 362,KT362,KT-362	Potassium Channel , Calcium Channel , Sodium Channel
	KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels, potassium channels and sodium channels.KT-362 fumarate causes vasodilation by affecting intracellular calcium mobilization in atrial mus...		Potassium Channel , Calcium Channel , Sodium Channel
T4674	SB297006	SB 297006	CCR
	SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ...		CCR
TP2106L	Urantide acetate(669089-53-6 free base)		Neurotensin Receptor
	Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3). Blocks hU-II induced contractions in thoracic aorta ex vivo. Exhibits no effect on noradrenaline or endothelin 1-induced ...		Neurotensin Receptor
T22794	G36	G-36	Estrogen Receptor/ERR
	G36 is a cell-permeable non-steroidal antagonist of GPER. G36 inhibits activation by either 17β-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 nM, respectively). G36 has no detectable binding activity to...		Estrogen Receptor/ERR
T12331L	OT-R antagonist 1	Oxytocin receptor antagonist 1	Others
	OT-R antagonist 1 inhibits oxytocin-evoked intracellular Ca2+ mobilization (IC50 = 8 nM). OT-R antagonist 1 is a new effective and selective nonpeptide low molecular weight OT-R antagonist.		Others
T28169	NIBR-0213	NIBR 0213	LPL Receptor
	NIBR-0213, a potent and selective S1P(1) antagonist, has efficacy in experimental autoimmune encephalomyelitis.		LPL Receptor
T37312	Isotachysterol 3
	Isotachysterol 3, an analog of 1,25-dihydroxy Vitamin D3, was found to enhance intestinal calcium transport and stimulate bone calcium mobilization in anephric rats[1].
T69385	Baicalein monohydrate
	Baicalein monohydrate is an inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis.
T62660	MLN3126
	MLN3126 is an orally active, potent CCR9 antagonist. MLN3126 inhibits CCL25-induced calcium mobilization and chemotaxis in mouse primary thymocytes with an IC50 value of 6.3 nM for calcium influx inhibition.
T35922	NAADP (sodium salt)
	Nicotinic acid adenine dinucleotide phosphate (NAADP) is a secondary messenger that induces calcium mobilization. It induces calcium release from endosomes and lysosomes via two-pore channel 2 (TPC2) and TPC1, which then...
T40948	KMG-104
	KMG-104 is a fluorescent magnesium (Mg2+) probe known for its exceptional selectivity. It has been extensively utilized to investigate the mobilization of Mg2+ in the cytoplasm across different cell types.
T16034	Meclinertant	SR 48692	Others
	Meclinertant is an effective, selective, nonpeptide, and orally active neurotensin receptor 1 (NTS1) antagonist. Meclinertant competitively antagonizes neurotensin-induced intracellular Ca2+ mobilization (pA2 : 8.13), in...		Others
T63661	HF51116
	HF51116 is a potent antagonist of XCR4. HF51116 significantly antagonizes SDF-1α-induced cell migration, calcium mobilization and CXCR4 internalization, and inhibits HIV-1 infection using CXCR4. HF51116 has shown investi...
T37529	TC NTR1 17
	Non-peptide neurotensin receptor 1 (NTS1) partial agonist (EC50 <15.6 nM and Emax = 63% of neurotensin response in Ca2+ mobilization assay). Exhibits over 50-fold selectivity for NTS1 over NTS2 and GPR35. Hershberger et ...
T68959	Fenobam hydrate
	Fenobam hydrate is a noncompetitive antagonist and inverse agonist of metabotropic glutamate receptor 5 (mGluR5). It inhibits intracellular calcium mobilization induced by the glutamate analog quisqualate and inhibits ba...
TP1981	Neuropeptide S(Mouse)	Neuropeptide S (Mouse)
	Potent endogenous neuropeptide S receptor (NPSR) agonist (EC50 = 3 nM). Induces mobilization of intracellular Ca2+. Increases locomotor activity and wakefulness in mice. Also reduces anxiety-like behavior in mice.
T69357	AL-34662
	AL-34662 is a serotonin-2 receptor agonist with antihypertensive action. AL-34662 has a high-affinity for the 5-HT2 receptor and may potentially lead mobilization of [Ca2+]i in h-CM and h-TM cells leading to a decrease ...
T38227	Quin C1
	Potent and selective FPR2 agonist (EC50 = 15 nM). Induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells. Induces neutrophil chemotaxis and degranulation in vitro. Reduces neutrophil and lymphocyte counts ...
T81279	RhB-PBP10 TFA
	RhB-PBP10 TFA, a Rhodamine B-labeled PBP10 TFA (FPR2 antagonist), selectively inhibits granule mobilization and oxygen radical secretion in FPRL1-induced neutrophils [1].
T75950	Neuropeptide S(Mouse) TFA
	Neuropeptide S(Mouse) TFA, an endogenous agonist for the neuropeptide S receptor (NPSR) with an EC50 value of 3 nM, plays a significant role in physiological processes by inducing the mobilization of intracellular Ca2+. ...
T61359	CXCR2 antagonist 6
	CXCR2 antagonist 6 (compound 35c) is a potent CXCR2 antagonist. CXCR2 antagonist 6 shows potent CXCR2 binding affinity ( IC 50 =0.044 μM) and calcium mobilization ( IC 50 =0.66 μM) [ 1].
T61235	CXCR2 antagonist 5
	CXCR2 antagonist 5 (compound 25) is a potent CXCR2 antagonist. CXCR2 antagonist 5 shows potent CXCR2 binding affinity ( IC 50 =0.013 μM) and calcium mobilization ( IC 50 =0.1 μM) [ 1].
T6764	ATI-2341	ATI2341	CXCR
	ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is an allosteric agonist activating the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobil...		CXCR
T61236	CXCR2 antagonist 7
	CXCR2 antagonist 7 (compound 19) is a potent CXCR2 antagonist. CXCR2 antagonist 7 shows potent CXCR2 binding affinity ( IC 50 =0.044 μM) and calcium mobilization ( IC 50 =0.66 μM) [ 1].
T4186	AC-264613	AC264613	Protease-activated Receptor
	AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macropha...		Protease-activated Receptor
T36634	ZQ 16
	Selective medium-chain free fatty acid receptor GPR84 agonist (EC50 = 139 nM). Exhibits no response at GPR40, GPR41, GPR119 or GPR120 at 100 μM. Activates calcium mobilization, inhibits cAMP accumulation, and induces ERK...
T81391	Prolactin-Releasing Peptide (12-31), rat
	Prolactin-Releasing Peptide (12-31), rat, a fragment of PrRP, exhibits high affinity for GPR10 receptors and stimulates calcium mobilization in CHOK1 cells transfected with the PrRP receptor [1] [2].
T78600	VU0029251
	VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM. It also attenuates glutamate-induced calcium mobilization in HEK293 cell membranes that express rat mGluR5, demonst...
T60655	Resomelagon
	Resomelagon (AP1189) is a potent, orally active agonist of melanocortin receptor (MR) that induces Ca2+ mobilization and ERK1/2 phosphorylation. Resomelagon shows anti-inflammatory activity that can be used in obesity an...
T75815	WKYMVM-NH2 TFA
	WKYMVM-NH2 TFA, a potent agonist for N-formyl peptide receptor (FPR1) and FPRL1/2, activates key leukocyte effector functions including chemotaxis, complement receptor-3 mobilization, and NADPH oxidase activation, as doc...
T74650	JPE-1375
	JPE-1375, a complement C5a receptor 1 (C5aR1) antagonist, effectively inhibits polymorphonuclear leukocyte mobilization (EC50=6.9 µM) and reduces TNF levels (EC50=4.5 µM) in mice, making it useful for autoimmune and infl...
T36982	CXCR3 Antagonist 6c
	CXCR3 antagonist 6c is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3).1It inhibits calcium mobilization induced by chemokine (C-X-C motif) ligand 11 (CXCL11) in HEK293 cells expressing the human receptor (IC...
T36296	BIO5192 hydrate
	BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 hydrate selectively binds to α4β1 (IC50=1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase...
T62140	HF50731
	HF50731 is a potent antagonist of CXCR4. HF50731 has a strong binding affinity for CXCR4 (IC50: 19.8 nM). HF50731 utilizes the CXCR4 co-receptor and effectively inhibits calcium mobilization (IC50: 119.2 nM), cell migrat...
T80421	CSD-CH2(1,8)-NH2		Opioid Receptor
	CSD-CH2(1,8)-NH2 is a selective and competitive kappa-opioid receptor (KOR) antagonist with a K i of 6.8 nM. It inhibits calcium mobilization in dorsal root ganglion (DRG) neurons and antagonizes the antinociceptive effe...		Opioid Receptor
T75866	RFRP-3(human) TFA
	RFRP-3 (Neuropeptide VF(124-131))(human) TFA, a human homolog of the GnIH peptide, significantly suppresses gonadotropin release through inhibition of Ca 2+ mobilization. Acting as an NPFF1 receptor agonist, RFRP-3 (huma...
T72536	GPR84 antagonist 2
	GPR84 Antagonist 2, a potent and selective GPR84 antagonist (IC 50 = 8.95 nM), demonstrates oral activity and significantly enhances potency in calcium mobilization assays. It effectively inhibits neutrophil and macropha...
T41016	Vercirnon sodium	GSK-1605786 sodium,CCX282-Bsodium,Traficet-ENsodium
	Vercirnon (GSK1605786A) sodium is an orally bioavailable, selective, and potent CCR9 antagonist. It effectively inhibits CCR9-mediated calcium mobilization and chemotaxis in Molt-4 cells, exhibiting IC50 values of 5.4 nM...
T35745	Marcfortine A
	Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99 = 0.06 μg/ml) and inhibits motility of adult worms (EC50 = 2 μM).,...

Compounds

Target: ROS, Complement System

Synonym: VU-0422288,ML-396,ML396,VU 0422288,ML 396

Synonym: MLS000051547,MLS 1547,MLS-1547

Target: Dopamine Receptor

Target: Proteasome, Protease-activated Receptor

RFRP3(human) acetate(311309-27-0 free base)

TP1936L1

Synonym:

Target: Neuropeptide Y Receptor

ATI-2341 acetate(1337878-62-2 free base)

Synonym: KT 362,KT362,KT-362

Target: Potassium Channel, Calcium Channel, Sodium Channel

Urantide acetate(669089-53-6 free base)

TP2106L

Synonym:

Target: Neurotensin Receptor

G36

T22794

Synonym: G-36

Target: Estrogen Receptor/ERR

OT-R antagonist 1

T12331L

Synonym: Oxytocin receptor antagonist 1

Baicalein monohydrate

Neuropeptide S(Mouse)

TP1981

Synonym: Neuropeptide S (Mouse)

Neuropeptide S(Mouse) TFA

Target: Protease-activated Receptor

Prolactin-Releasing Peptide (12-31), rat

Target: Opioid Receptor

Synonym: GSK-1605786 sodium,CCX282-Bsodium,Traficet-ENsodium

カタログ番号	製品名	別名	ターゲット
T5246	Trans-2-butene-1,4-dicarboxylic acid	trans-2-Butene-1,4-dicarboxylic Acid,3-Hexenedioic Acid,trans-3-Hexenedioic Acid,β-Hydromuconic Acid	Others , Endogenous Metabolite
	Trans-2-butene-1,4-dicarboxylic acid (3-Hexenedioic Acid) is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disorde...		Others , Endogenous Metabolite
T19253	Cyclic ADP-ribose	cADPR	Calcium Channel
	Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger, which is synthesized from NAD + by ADP-ribosyl cyclase. Cyclic ADP-ribose mainly increases cytosolic calcium through Ryanodine receptor-med...		Calcium Channel
TN2918	3-Acetoxy-8(17),13E-labdadien-15-oic acid		cAMP , Potassium Channel , Calcium Channel
	ent-3-Acetoxy-labda-8(17),13-dien-15-oic acid have vasorelaxant and hypotensive actions, the mechanisms underlying the cardiovascular actions of the labdane involve the activation of the endothelial NO-cGMP pathway, the ...		cAMP , Potassium Channel , Calcium Channel
TN5580	Rediocide A
	Rediocide A, an insecticide, can inhibit calcium mobilization in Drosophila G-protein- coupled receptors (GPCR)s other than methuselah, it can induce GPCR desensitization and internalization, and such effects are mediate...
T37687	Cyclic ADP-ribose ammonium
	Cyclic ADP-ribose ammonium (cADPR ammonium) is a powerful calcium mobilization second messenger synthesized from NAD+ by an ADP-ribosyl cyclase. It primarily raises cytosolic calcium levels through Ryanodine receptor-med...
TN3319	9-Hydroxycanthin-6-one		Potassium Channel , GSK-3 , Calcium Channel , Wnt/beta-catenin
	9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as well as SV probably through interfering with Ca2+ mobilizat...

天然物製品

Trans-2-butene-1,4-dicarboxylic acid

T5246

Synonym: trans-2-Butene-1,4-dicarboxylic Acid,3-Hexenedioic Acid,trans-3-Hexenedioic Acid,β-Hydromuconic Acid

Target: Others, Endogenous Metabolite

Cyclic ADP-ribose

T19253

Synonym: cADPR

Target: Calcium Channel

3-Acetoxy-8(17),13E-labdadien-15-oic acid

TN2918

Synonym:

Target: cAMP, Potassium Channel, Calcium Channel

Cyclic ADP-ribose ammonium

T37687

Synonym:

Target:

9-Hydroxycanthin-6-one

TN3319

Synonym:

Target: Potassium Channel, GSK-3, Calcium Channel, Wnt/beta-catenin

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03066	FLT3 Ligand Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of th...
TMPY-06873	FLT3 Ligand Protein, Human, Recombinant	Human	E. coli
	FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of th...
TMPY-03215	FLT3 Ligand Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of th...
TMPY-02333	ULBP-2 Protein, Human, Recombinant (His)	Human	HEK293
	NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPY-05592	ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated	Human	HEK293
	NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPY-01774	TREM-1 Protein, Human, Recombinant (His)	Human	HEK293
	TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPY-05636	G-CSF Protein, Mouse, Recombinant	Mouse	HEK293
	Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-02170	SCF Protein, Human, Recombinant (aa 1-189, His)	Human	Baculovirus-Insect Cells
	Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod...
TMPY-04829	G-CSF Protein, Human, Recombinant	Human	HEK293
	Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-02105	SCF Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod...
TMPH-01822	P2Y1 Protein, Human, Recombinant (His)	Human	E. coli
	Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately p...
TMPH-02528	SLC7A10 Protein, Mouse, Recombinant (His & SUMOstar)	Mouse	Yeast
	Sodium-independent, high affinity transport of small neutral D- and L-amino acids and amino acid-related compounds. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the ...
TMPH-02541	Beta Defensin 1/DEFB1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization i...
TMPK-00136	ULBP-2 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, E...
TMPH-03101	DEFB1 Protein, Pig, Recombinant (GST)	Sus scrofa (Pig)	E. coli
	Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization i...
TMPH-01301	Erythroferrone Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increase...
TMPK-00271	TPBG/5T4 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR...
TMPK-00270	TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled	Human	HEK293
	The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR...
TMPH-02658	FPR1 Protein, Mouse, Recombinant (GST & His & Myc)	Mouse	E. coli
	High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release...
TMPH-02646	Erythroferrone Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increase...
TMPH-01346	FPR1 Protein, Human, Recombinant (GST & His & Myc)	Human	E. coli
	High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release...
TMPK-00327	CD19 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus macaque	HEK293
	CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses.Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases th...
TMPH-03265	CMKLR2 Protein, Rat, Recombinant (His)	Rat	in vitro E. coli expression system
	Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates...
TMPH-01330	FCRL3 Protein, Human, Recombinant (His)	Human	E. coli
	Promotes TLR9-induced B-cell proliferation, activation and survival but inhibits antibody production and suppresses plasma cell differentiation. Enhances activation of NF-kappa-B and MAPK signaling pathways in TLR9 stimu...
TMPH-03296	Galectin-3/LGALS3 Protein, Rat, Recombinant (His)	Rat	E. coli
	Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute infl...
TMPJ-00019	CCL28 Protein, Human, Recombinant	Human	E. coli
	Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and i...
TMPY-05332	FLT3 Ligand Protein, Rat, Recombinant (His)	Rat	Baculovirus-Insect Cells
	FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of th...
TMPY-02334	ULBP-2 Protein, Human, Recombinant (hFc)	Human	HEK293
	NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPH-01071	CD44 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellu...
TMPH-01072	CD44 Protein, Human, Recombinant (Avi & mFc), Biotinylated	Human	HEK293
	Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellu...
TMPH-01082	CMKLR1 Protein, Human, Recombinant (His)	Human	in vitro E. coli expression system
	Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 initiates activation of G proteins G(i)/G(o) and beta-arrestin pathways in...
TMPJ-00741	PTH Protein, Human, Recombinant (His)	Human	Human Cells
	Parathyroid hormone (PTH) is a critical hormone in the regulation of Ca++ homeostasis. Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This ho...
TMPY-03576	Syndecan-4 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in th...
TMPY-02392	Syndecan-4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in th...
TMPY-05300	Syndecan-4 Protein, Human, Recombinant (His)	Human	HEK293
	SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in th...
TMPY-02131	Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST)	Human	E. coli
	The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of im...
TMPY-06527	TREM-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPY-00943	TREM-1 Protein, Human, Recombinant (His & hFc)	Human	HEK293
	TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPH-02168	TRAC Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize p...
TMPH-02171	TRBC2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02173	TRBC2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02167	TRAC Protein, Human, Recombinant (His)	Human	Yeast
	Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize p...
TMPH-02172	TRBC2 Protein, Human, Recombinant (His)	Human	Yeast
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02170	TRBC1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02169	TRBC1 Protein, Human, Recombinant (His)	Human	Yeast
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPY-03824	CD43 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	CD43 is an abundantly expressed molecule on the T-cell surface that shows distinct localization to the migrating T-cell uropod and the distal pole complex (DPC) opposite the immunological synapse via association with the...
TMPY-02435	CD43 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	CD43 is an abundantly expressed molecule on the T-cell surface that shows distinct localization to the migrating T-cell uropod and the distal pole complex (DPC) opposite the immunological synapse via association with the...
TMPY-00813	G-CSF Protein, Human, Recombinant (hFc)	Human	HEK293
	Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-05135	SCF Protein, Mouse, Recombinant (His), Biotinylated	Mouse	Baculovirus-Insect Cells
	Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod...
TMPH-01768	VGF Protein, Human, Recombinant (GST & His & Myc)	Human	E. coli
	Secreted polyprotein that is packaged and proteolytically processed by prohormone convertases PCSK1 and PCSK2 in a cell-type-specific manner. VGF and peptides derived from its processing play many roles in neurogenesis a...
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