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T8648 |
6-AZATHYMINE
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Nucleoside Antimetabolite/Analog
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Influenza Virus
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DNA/RNA Synthesis
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Antibacterial
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6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic... |
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T19446 |
N-Boc-O-tosyl hydroxylamine
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Others
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N-Boc-O-tosyl hydroxylamine is nitrogen source for the N-amination of aryl and alkyl amines. |
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T1337 |
Pamidronate Disodium
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CGP 23339A,CGP 23339AE,Pamidronate disodium salt |
Others
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HBV
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Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones. |
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T6373 |
Alendronate sodium hydrate
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G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,G-704650 Adronat,Fosamax |
Transferase
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Alendronate sodium hydrate (MK 217) is a nitrogen-containing bisphosphonate, which is an effective inhibitor of bone resorption. It is utilized for the treatment and prevention of osteoporosis. |
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T20163 |
Acetyltrialanine
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Acetyltrialanine is a dipeptide compound that binds at two sites on the Tb+3-pancreatic elastase complex and can be used as a nitrogen source. |
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T1599L |
Ibandronate sodium
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Boniva,Ibandronate sodium salt,Bondronat |
HBV
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Transferase
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Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis. |
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T6539 |
Ibandronate sodium monohydrate
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Boniva monohydrate,Bondronat monohydrate,Ibandronate sodium,BM-210955,BM-21.0955,RPR-102289A |
Apoptosis
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Others
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Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis. |
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T16539 |
Piperazine citrate
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GABA Receptor
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Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmintic. |
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T18910 |
Acid Yellow 9 monosodium salt
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Hydrogen 4-aminoazobenzene-3,4'-disulphonate (sodium salt) |
Others
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Acid Yellow 9 monosodium salt (Hydrogen 4-aminoazobenzene-3,4'-disulphonate (sodium salt)) is an azo dye, degraded by Pseudomonas fluorescens as a sole source of nitrogen, carbon, and energy for the bacterium. |
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T11031 |
HDHODH-IN-7
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DHODH-IN-9 |
Dehydrogenase
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hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor. hDHODH-IN-7 and pMIC50 of 7.4 have antiviral effects. |
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T0975 |
Chlorambucil
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CB-1348,Chloroambucil,WR-139013 |
DNA Alkylator/Crosslinker
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DNA Alkylation
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Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arr... |
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T22096 |
L 012 sodium salt
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L 012 sodium salt, a luminol analogue, is a widely used chemiluminescent (CL) probe for active oxygen and active nitrogen. L 012 sodium salt is widely used to detect the superoxides (O2•−) derived from NADPH oxidase (Nox... |
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T1055 |
Ifosfamide
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NSC109724,Isophosphamide |
DNA Alkylator/Crosslinker
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DNA/RNA Synthesis
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Ifosfamide (NSC-109724) alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. Ifosfamide is a synthetic analog of the nitrogen mustard cyclophosphamide with antineoplastic acti... |
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T1347 |
2-Benzothiazolamine
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2-Aminobenzothiazole |
IL Receptor
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Others
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2-Benzothiazolamine (2-ABT) is a nitrogen-containing heterocyclic compound used as a reaction intermediate in the synthesis of a variety of drugs. It inhibits cytochrome P450 activity and has also shown anti-inflammatory... |
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T20681 |
Estramustine
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NSC-89201,NSC 89201,LEO 275,LEO275,NSC89201,LEO-275 |
Microtubule Associated
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Estramustine (LEO-275) is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties. Estramustine is selectively taken... |
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T1098 |
Denatonium benzoate
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THS-839 |
Others
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Denatonium benzoate (THS-839) , a quaternary ammonium cation, is a compound of a salt with an inert anion like saccharide or benzoate. Its structure is involved in the local anesthetic lidocaine which difference only is ... |
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T1006 |
Propantheline bromide
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Neopepulsan,Pro-Banthine,Neometantyl |
AChR
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Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromid... |
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T40691 |
Bromodichloroacetonitrile
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Bromodichloroacetonitrile is a nitrogen-containing disinfection byproduct. |
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T32518 |
Labriformine
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Labriformin |
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Labriformine is a nitrogen-containing cardenolide of low polarity, predominated in the latices. |
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T13900 |
Arrhythmic-Targeting Compound 1
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Others
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Arrhythmic-Targeting Compound 1 is used for arrhythmic disease, with nitrogen-containing spirocycles. |
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T40868 |
Tribromoacetonitrile
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Tribromoacetonitrile is a nitrogen-containing disinfection byproduct. |
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T24453 |
Metamelfalan
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NSC-67781,Metamelfalanum,NSC67781,NSC 67781,m-L-Sarcolysin |
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Metamelfalan is an alkylating nitrogen mustard with potential antineoplastic activity. It causes crosslinking of DNA, thereby preventing DNA replication and eventually cellular proliferation. |
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T40734 |
Diquat dibromide hydrate
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Diquat dibromide hydrate is a diazine-like herbicide including two nitrogen atoms. |
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T70054 |
Novembichin
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Novembichin is a nitrogen mustard agent that crosslinks with DNA, causing inhibition of DNA synthesis. |
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T28436 |
Polyoxin B
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Polyoxin-B |
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Polyoxin B is a nucleoside antibiotics composed of heterocyclic moieties containing nitrogen. Polyoxin B inhibits the biosynthesis of chitin. |
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T25391 |
Estromustine
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Leo-271 f,Leo 271 f,Leo271 f |
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Estromustine is a major active metabolite of the cystotatic estrogen and nitrogen mustard alkylating antineoplastic agent estramustine phosphate, used in the therapy of prostate cancer. |
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T20163L |
Acetyltrialanine acetate
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Acetyltrialanine acetate(19245-85-3 Free base) |
Others
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Acetyltrialanine acetate is the nitrogen source of mutants of Salmonella typhimurium. |
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T31639 |
Enpromate
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Lilly59156,NSC 112682,59156,Lilly 59156,Lilly-59156 |
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Enpromate is a synthetic acetyl carbamate, nitrogen mustard compound. It is an alkylating agent with antitumor activity. |
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T25299 |
Degranol
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NSC 9698,NSC-9698,NSC9698 |
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Degranol is a nitrogen mustard derivative alkylating agent utilized as antineoplastic. It causes severe bone marrow depression and is a powerful vesicant. |
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T25723 |
L-Ifosfamide
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(+)-Ifosfamide |
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L-Ifosfamide is nitrogen mustard, a chemotherapeutic antineoplastic, and more precisely an alkylating agent structural analog of cyclophosphamide with respect to which presents some differences regard to the antitumor ac... |
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T17184 |
Tyrosine kinase inhibitor
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c-Met/HGFR
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Tyrosine Kinases
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Tyrosine kinase inhibitor is a tyrosine kinase inhibitor used in combination with fragmenting aromatic nitrogen compounds as antiproliferative agents. |
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T34523 |
Sarcolysine hydrochloride
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DL-Phenylalanine mustard hydrochloride,Melphalan,DL-Sarcolysine hydrochloride,DL-Sarcolysin monohydrochloride,AI3-52155,Alkeran |
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Sarcolysine hydrochloride, also known as Melphalan HCl, is a nitrogen mustard and alkylating agent that has been studied for use in multiple myeloma therapy. |
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T33390 |
MIND4
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MIND 4,MIND-4 |
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Mind4 is an inducer of cytoprotective Nrf2 activity. Mind4 induces Nrf2 activation and reduces the production of reactive oxygen species and nitrogen intermediates in neurons and non neurons. |
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T78447 |
2-(Naphthalen-1-yl)-5-phenyloxazole
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α-NPO |
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2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye with a nitrogen atom within its structure, which may interact with the nitrogen introduced during the amination step [1]. |
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T29851 |
Aldoifosfamide
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UNII-S1JX147O5E,Mitoxana,Ifex |
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Aldoifosfamide is a metabolite of ifosfamide. Ifosfamide (also marketed as Mitoxana and Ifex) is a nitrogen mustard alkylating agent used in the treatment of cancer. It is sometimes abbreviated 'IFO''. |
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T68738 |
(±)-γ-Tocopherol
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(±)-γ-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties. It traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays. It also reduces the syn... |
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T16433 |
Pancopride
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LAS 30451 |
5-HT Receptor
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Pancopride（LAS 30451） is a novel, orally available, long-acting, selective 5-HT3 receptor antagonist that blocks nitrogen mustard and dacarbazine-induced vomiting. |
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T37675 |
3-Deaza-2'-deoxyadenosine
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3-Deaza-2'-deoxyadenosine strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM. This nucleoside can also be used to evaluate the role of the adenine N3 nitrogen in DNA structure an... |
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T13763 |
LY88074 analog 1
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Others
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LY88074 analog 1, a benzothiophene compound with nitrogen-containing non-basic side chains, can be utilized either independently or alongside estrogen or progestin. This agent is effective for mitigating post-menopausal ... |
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T35996 |
FeTPPS
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Peroxynitrite is a highly reactive nitrogen species formed from the reaction of nitric oxide (NO) and superoxide.[1] FeTPPS is a ferric porphyrin complex that causes the decomposition of peroxynitrite by catalytic isomer... |
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T40947 |
PR-104 sodium
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PR-104 sodium is a hypoxia-activated DNA cross-linking agent used in the research of tumor xenograft models. It functions as a nitrogen mustard pre-prodrug and efficiently transforms into the more lipophilic dinitrobenza... |
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T72335 |
KRAS G12C inhibitor 32
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Ras
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KRAS G12C Inhibitor 32, an eight-membered heterocyclic compound with nitrogen, acts as a potent inhibitor of KRAS G12C [1]. |
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T36302 |
PR-104
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PR-104 is a highly specific hypoxia-activated agent that cross-links DNA, enabling its application in various tumor xenograft models. Functioning as a pre-prodrug of nitrogen mustard, PR-104 undergoes efficient conversio... |
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T39441 |
L-Arginine-15N4 hydrochloride
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L-Arginine-15N4 hydrochloride,(S)-(+)-Arginine-15N4 hydrochloride |
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L-Arginine-15N4 ((S)-(+)-Arginine-15N4) hydrochloride, the 15N-labeled variant of L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride), serves as the nitrogen donor in the synthesis of nitric oxide. This potent vaso... |
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T75312 |
Citric acid triammonium
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Triammonium citrate, also known as citric acid triammonium, results from the reaction between citric acid and ammonia at a 1:3 molar ratio. This compound serves as a carbon source for the synthesis of carbon quantum dots... |
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T75239 |
C-Myc inhibitor 10
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C-Myc Inhibitor 10 (compound 17), exhibiting enhanced cellular potency, benefits from increased permeability due to the methylation of the morpholine nitrogen [1]. |
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T25073 |
Ambamustine
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Ambamustine, also known as PTT 119, is a tripeptide nitrogen mustard compound, which is a DNA inhibitor and DNA alkylating agent with antitumor activity. It has been studied for the treatment of tumors, immune system dis... |
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T37000 |
7-Azido-4-methylcoumarin
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7-Azido-4-methylcoumarin (AzMC) is a coumarin fluorescent probe for hydrogen sulfide (H2S).1 AzMC selectively fluoresces in the presence of H2S over a panel of reactive nitrogen, oxygen, and sulfur species. AzMC displays... |
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T36697 |
8-Nitroguanine
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8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant fibrous histiocytoma. |
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T83019 |
Antiproliferative agent-38
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Antiproliferative Agent-38 (COM 18), a tetracyclic compound, features a reactive ring nitrogen (likely the quinoline moiety) that resists N-alkylation. Despite its classification, it neither exhibits anti-malarial proper... |
