|
T20062 |
Thiamine disulfide
|
TDS,Daiomin,Algoneurina |
HIV Protease
,
Endogenous Metabolite
|
|
Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication. Thiamine also acts as a cofactor for many centrally metabolizing... |
|
T6255 |
Bromosporine
|
|
Epigenetic Reader Domain
,
CDK
|
|
Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively. |
|
T6098 |
Cabotegravir
|
GSK744,GSK-1265744,S/GSK1265744 |
HIV Protease
|
|
Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM). |
|
T7212 |
Delavirdine mesylate
|
U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate) |
HIV Protease
,
Reverse Transcriptase
|
|
Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI). |
|
T1595 |
Nevirapine
|
NSC 641530,BI-RG 587,NVP |
HIV Protease
,
Reverse Transcriptase
|
|
Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preve... |
|
T3335 |
Darunavir Ethanolate
|
UIC 94017,Darunavir Ethanolate,TMC114 |
HIV Protease
|
|
Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination... |
|
T4697 |
ABBV-744
|
ABBV744 |
Epigenetic Reader Domain
,
HIV Protease
|
|
ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS. |
|
T1267 |
Abacavir
|
Epzicom,Ziagen,Abacavir sulfate |
Apoptosis
,
HIV Protease
,
Reverse Transcriptase
|
|
Abacavir (Ziagen) is a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS. |
|
T2324 |
Darunavir
|
TMC114 |
HIV Protease
|
|
Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other AN... |
|
T3632 |
Doravirine
|
MK-1439 |
HIV Protease
,
Reverse Transcriptase
|
|
Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS. |
|
T7903 |
Saquinavir
|
Ro 31-8959 |
SARS-CoV
,
HIV Protease
|
|
Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS. |
|
T24362 |
L 756423
|
L756423,MK-944a,MK944a,L-756,423,L-756423,MK 944a |
HIV Protease
|
|
L 756423 (L756423) is a novel potent and selective and competitive HIV protease inhibitor with a Ki value of 0.049 nM for HIV-1 PR.L 756423 blocks the spread of HIV(IIIb)-infected MT25 lymphocytes at 0.50-0.1 nM and can ... |
|
T0688 |
Ganciclovir
|
BW 759,RS-21592,2'-Nor-2'-deoxyguanosine |
Nucleoside Antimetabolite/Analog
,
Others
,
Antibiotic
,
Antifection
,
HSV
|
|
Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegaloviru... |
|
T0100 |
Atazanavir sulfate
|
BMS-232632,BMS-232632 sulfate |
P450
,
SARS-CoV
,
HIV Protease
,
P-gp
|
|
Atazanavir sulfate (BMS-232632 sulfate) is an azapeptide and HIV-PROTEASE INHIBITOR that is used in the treatment of HIV INFECTIONS and AIDS in combination with other ANTI-HIV AGENTS. |
|
T6367 |
Abacavir sulfate
|
Abacavir Hemisulfate,1592U89,ABC sulfate,Ziagen |
Apoptosis
,
HIV Protease
,
Reverse Transcriptase
|
|
Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity |
|
T8736 |
Cidofovir dihydrate
|
HPMPC,(S)-HPMPC,GS 0504 |
Others
|
|
Cidofovir dihydrate (HPMPC) is an anti-CMV drug, It can suppress CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. Cidofovir dihydrate is an ... |
|
T8826 |
3-AMINO-1,2,4-TRIAZINE
|
|
Others
|
|
3-AMINO-1,2,4-TRIAZINE is an aromatic bioactive compound. It has been used to synthesize a variety of drugs, including the antifungal drug fluconazole, the anti-inflammatory drug ibuprofen and the anticancer drug paclita... |
|
T1525 |
Ritonavir
|
RTV,Abbott 84538,A 84538,ABT 538 |
Apoptosis
,
SARS-CoV
,
HIV Protease
|
|
Ritonavir (ABT 538) is a peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other HIV proteases by blocking their degradation by cy... |
|
T0377 |
Clofazimine
|
NSC-141046 |
DNA
,
Antibacterial
,
Antibiotic
|
|
Clofazimine (NSC-141046) is a phenazine dye with anti-mycobacterial and anti-inflammatory activities. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against various other Mycobacteria. |
|
T25535 |
Indinavir, threo-
|
Threo-indinavir,Indinavir sulfate specified impurity C |
|
|
Indinavir, threo- is a protease inhibitor utilized as a component of highly active antiretroviral treatment to HIV/AIDS. |
|
T70717 |
KNI 174
|
|
|
|
KNI 174 is a new type of anti‐AIDS drug used as an HIV‐1 protease inhibitor |
|
T69796 |
Nevirapine hemihydrate
|
|
|
|
Nevirapine hemihydrate is a non-nucleoside reverse transcriptase inhibitor (NNRTI) studied for potential treatment of HIV-1 infection and AIDS. |
|
T5863L |
Indinavir
|
MK-639,L 735 524,Crixivan |
|
|
Indinavir (IDV) is an inhibitor of protease that is used as part of highly active antiretroviral therapy for the treatment of HIV/AIDS. |
|
T68376 |
Indinavir lactone
|
|
|
|
Indinavir lactone is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV/AIDS. |
|
T70147 |
Fipravirimat
|
|
|
|
Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research. |
|
T74106 |
Hydroxy ritonavir
|
|
|
|
Hydroxy ritonavir, a metabolite of ritonavir, functions as an inhibitor of the HIV protease, thereby serving as a treatment for HIV infection and AIDS [1]. |
|
T62690 |
HIV-1 inhibitor-46
|
|
|
|
HIV-1 inhibitor-46 (compound 13d) is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (EC50: 1.425 μM). HIV-1 inhibitor-46 can be used in the study of AIDS. |
|
T27171 |
Diethylhomospermine
|
DEHOP,BE-4-4-4,DEHSPM,DE-444 |
|
|
Diethylhomospermine is a drug potentially for the treatment of AIDS-related chronic diarrhea.Diethylhomospermine also shows promising anticancer activity. |
|
T71983 |
Zidovudine glucuronide
|
|
|
|
Zidovudine glucuronide is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptas... |
|
TP2401 |
Peptide T amide
|
D-Ala(1)-peptide T amide |
|
|
Peptide T amide is an octapeptide segment of HIV envelope gp120 and is used in AIDS therapy. |
|
T28306 |
PD 099560
|
PD099560,PD-099560 |
|
|
PD 099560 is a non-peptide inhibitor of HIV-1 protease, a significant target enzyme in AIDS research. |
|
T71517 |
Nevirapine quinone methide
|
|
|
|
Nevirapine quinone methide is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS. |
|
T39068 |
Fomivirsen sodium
|
|
|
|
Fomivirsen sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen is an antiviral agent that is used cytomegalovirus retinitis (CMV) research, incluiding in AIDs. Fomivirsen sodium binds to and degrad... |
|
T71066 |
Cidofovir sodium
|
|
|
|
Cidofovir sodium is the salt form of Cidofovir, a Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor that is an injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis in... |
|
T19228 |
Calcitriol Impurities D
|
24-Homo Calcitriol,24-Homo-1,25-dihydroxyvitamin D3 |
Antiviral
|
|
Calcitriol Impurities D (24-Homo Calcitriol) is a hormonal form of the vitamin that promotes the differentiation of HL-60 human promyelocytic leukemia cells into monocytes.Calcitriol Impurities D has bone resorption acti... |
|
T63602 |
DdCTP trisodium
|
|
|
|
ddCTP trisodium is a nucleoside analogue that targets the human immunodeficiency virus (HIV) reverse transcriptase and is used in AIDS research. ddCTP trisodium is a class of dideoxyribonucleotides (ddNTPs) and a DNA pol... |
|
T62782 |
HIV-1 inhibitor-34
|
|
|
|
HIV-1 inhibitor-34 (compound 5q) is a potent, selective HIV-1 inhibitor that acts on HIV-1 (EC50: 6.4 nM), MT-4 cells (CC50: 16 μM). HIV-1 inhibitor-34 can be used in AIDS research. |
|
T71518 |
Zidovudine diphosphate
|
|
|
|
Zidovudine diphosphate is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptas... |
|
T74939 |
HIV protease-IN-1
|
|
|
|
HIV protease-IN-1 (compound 1·succinate), a potent non-peptidic inhibitor of HIV protease, is utilized for AIDS research [1]. |
|
T75232 |
2’-O-Acetyl-5’-O-benzoyl-3’-O-(2-methoxyethyl) uridine
|
|
|
|
2’-O-Acetyl-5’-O-benzoyl-3’-O-(2-methoxyethyl) uridine, an analog of uridine known for its potential antiepileptic properties, is utilized in researching anticonvulsant and anxiolytic activities. Additionally, it aids in... |
|
T62070 |
HIV-1 inhibitor-31
|
|
|
|
HIV-1 inhibitor-31 (compound 4) is a potent inhibitor of HIV-1. HIV-1 inhibitor-31 can be used in the study of AIDS. |
|
T72568 |
HIV-1 inhibitor-53
|
|
HIV Protease
|
|
HIV-1 Inhibitor-53 is a dual inhibitor targeting both the HIV-1 protease (PR) with an IC50 value of 1.93 nM and reverse transcriptase (RT) with an IC50 of 2.35 μM. It serves as a potent agent for AIDS research [1]. |
|
T63306 |
HIV-1 inhibitor-32
|
|
|
|
HIV-1 inhibitor-32 is a potent inhibitor of HIV-1 that acts on wild-type HIV (IC50: 34 nM) and can be used in AIDS research. |
|
T80963 |
TPEQM-DMA
|
|
|
|
TPEQM-DMA, a NIR-II photosensitizer, selectively accumulates in cancerous mitochondria and demonstrates potent type-I phototherapeutic efficacy that inhibits the growth of cancer cells. This efficacy aids in overcoming t... |
|
T83488 |
[Lys8] Vasopressin Desglycinamide
|
|
|
|
[Lys8] Vasopressin Desglycinamide, a vasopressin analog, supports the maintenance of active and passive avoidance behavior and aids in the facilitation of memory consolidation processes [1]. |
|
T64303 |
ZLM-66
|
|
|
|
ZLM-66 is a doravirine analogue and a potent inhibitor of non-nucleoside reverse transcriptases (NNRTIs), acting on wild-type HIV-1 reverse transcriptase (IC50: 41 nM), wild-type HIV-1 (EC50: 13 nM) and cIAP1 (EC50: 0.32... |
|
T73749 |
Fomivirsen
|
|
|
|
Fomivirsen (ISIS-2922 free base), a 21-mer phosphorothioate antisense oligonucleotide, serves as an antiviral agent, particularly in CMV research, including AIDS studies. It functions by binding to and degrading the mRNA... |
|
T61311 |
HIV-1 inhibitor-30
|
|
|
|
HIV-1 inhibitor-30 (compound 10i) is a potent inhibitor of HIV-1, specifically targeting the RT DNA polymerase enzyme. It exhibits strong antiretroviral activity, with an EC 50 value of 40 nM and an IC 50 value of 80 nM.... |
|
T62353 |
HIV-1 inhibitor-33
|
|
|
|
HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor that acts on HIV-1 (EC50: 8.6 nM), MT-4 cells (CC50: 18 μM). HIV-1 inhibitor-33 can be used in the study of AIDS. |
|
T75789 |
CALP3 TFA
|
|
|
|
CALP3 TFA, a Ca2+-like peptide and potent Ca2+ channel blocker, activates EF hand motifs in Ca2+-binding proteins. It can mimic increased [Ca2+]i, modulating the activity of Calmodulin (CaM), Ca2+ channels, and pumps. Th... |
