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T36205 |
Methylcarbamyl PAF C-16
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Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. It is nearly equipotent with PAF C-16 in its abilit... |
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T37268 |
PAF C-16 Carboxylic Acid
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PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the remodeling" and 'de novo' pathways. It is a potent mediator of neutrophil migration and the production o... |
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T35805 |
C16 Sphingomyelin (d18:1/16:0)
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Sphingomyelin 16:0,N-Palmitoyl-D-sphingomyelin |
Endogenous Metabolite
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C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) is a phospholipid analog of phospholipid bilayer membranes, which can be used to study biofilm activity. |
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T37562 |
C16 Ceramide
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N-acylsphingosine,C16 Ceramide (d18:1/16:0),Palmitoyl Ceramide,N-Palmitoylsphingosine |
p53
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C16 Ceramide (Palmitoyl Ceramide) is a naturally occurring small molecule that activates p53 by directly and selectively binding to it. |
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T16550 |
PKR-IN-C16
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Others
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PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the A... |
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T9783 |
Boc-C16-COOH
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PROTAC Linker
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Boc-C16-COOH is a alkyl-chain-based PROTAC linker. Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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T40997 |
GLP-1R modulator C16
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GLP-1R modulator C16 |
Glucagon Receptor
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GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4. |
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T72978 |
c-Met-IN-16
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c-Met-IN-16 is a c-Met inhibitor that can be used for cancer research . |
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T29308 |
Lyso-PAF C-16
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Lyso-PAF C-16 is a biologically inactive precursor of platelet activating factor. |
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T2676 |
PF-04217903
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c-Met/HGFR
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MET Tyrosine Kinase Inhibitor PF-04217903 is an orally bioavailabe, small-molecule tyrosine kinase inhibitor with potential antineoplastic activity. |
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T24150 |
HR22C16
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HR-22-C-16,HR 22 C 16 |
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HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor. |
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T7760 |
Thalidomide-O-amido-C3-NH2 TFA
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Cereblon Ligand-Linker Conjugates 16 TFA,E3 Ligase Ligand-Linker Conjugates 52 TFA |
E3 Ligase Ligand-Linker Conjugate
,
Ligand for E3 Ligase
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Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-C3-NH2 TFA incorporates the Thalidomide based cereblon ligand and a linker... |
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TQ0219 |
MK-8033
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c-Met/HGFR
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MK-8033 is a new and selective dual ATP competitive c-Met/Ron inhibitor (IC50: 1 nM Wt c-Met). |
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T21547 |
PAF (C16)
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C16-PAF |
ERK
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MEK
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MAPK
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Endogenous Metabolite
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PAF (C16) is a potent MAPK and MEK/ERK activator that induces increased vascular permeability. PAF (C16) (PAF (C16)) is a platelet-activating factor, a phospholipid-derived mediator and a ligand for PAF G protein-coupled... |
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T35804 |
C16 Lactosylceramide (d18:1/16:0)
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C16 Lactosylceramide is an endogenous bioactive sphingolipid. It forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Pla... |
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T37872 |
C16 Galactosylceramide (d18:1/16:0)
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C16 Galactosylceramide (d18:1/16:0) |
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C16 Galactosylceramide is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid . |
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T38180 |
C16 Phytoceramide (t18:0/16:0)
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C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C16 Phytoceramide (t18:0/1... |
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T36149 |
13C C16 Sphingomyelin (d18:1/16:0)
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13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion. It is intended for use as an internal standard for the quantification of C16 sphingomyelin b... |
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T36859 |
C16 Globotriaosylceramide (d18:1/16:0)
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C16 Globotriaosylceramide (d18:1/16:0) |
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C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide . C16 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raj... |
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T37454 |
C16 dihydro Ceramide (d18:0/16:0)
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Ceramide (d18:0/16:0),Cer(d18:0/16:0),N-hexadecanoyl-D-erythro-Dihydrosphingosine,N-Palmitoyl Sphinganine |
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C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) that lacks the 4,5-trans double bond.[1] C16 dihydro Ceramide (0-46 nM) inhibits C16 ceramide-induced m... |
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T17648 |
Boc-C16-NHS ester
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Others
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Boc-C16-NHS ester, an alkyl/ether-based PROTAC linker, enables the synthesis of PROTACs[1]. |
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T39426 |
Thalidomide-O-amido-C3-NH2
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Thalidomide-O-amido-C3-NH2,Cereblon Ligand-Linker Conjugates 16,E3LigaseLigand-LinkerConjugates52 |
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Thalidomide-O-amido-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate, which combines the cereblon ligand derived from Thalidomide with a linker utilized in PROTAC technology. |
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T13314 |
VTX-27
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PKC
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VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ). |
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T1272L |
Cytarabine hydrochloride
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Ara-C hydrochloride,Cytosine Arabinoside hydrochloride |
DNA/RNA Synthesis
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Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC 50 of 16 nM. Cytarabine hydrochloride ... |
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T6517 |
Golvatinib
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E-7050 |
VEGFR
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c-Met/HGFR
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Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic ... |
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T22540L |
Ac-Endothelin-1 (16-21), human acetate
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Others
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Ac-Endothelin-1 (16-21), human acetate, the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which i... |
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T6079 |
NVP-ADW742
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ADW742,ADW,GSK 552602A |
Apoptosis
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IGF-1R
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NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit. |
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T8411 |
C-215
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Others
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C-215 is a novel inhibitor of mycobacterial membrane protein large 3 (MmpL3). |
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TP1604L |
Thioredoxin reductase peptide acetate
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Thioredoxin reductase peptide acetate(950890-23-0 free base) |
Others
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Thioredoxin reductase peptide acetate corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active... |
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T3157 |
COH29
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RNR Inhibitor COH29 |
DNA/RNA Synthesis
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COH29 (RNR Inhibitor COH29) is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase (RNR), with potential antineoplastic activity. Upon oral administration, the RNR i... |
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T33784 |
Oidiolactone B
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LL Z1271,NSC180975 PR 1387,NSC 180975,NSC-180975,LL-Z1271 |
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Oidiolactone B is a C(16) terpenoid lactone metabolite from Acrostalagmus. |
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T36764 |
PAF C-18:1
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PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response. It is less potent than PAF C-16 and PAF C-18 in the ... |
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T36763 |
PAF C-18
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PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the remodeling" and 'de novo' pathways. It is less potent than PAF C-16 in the induction of platelet aggrega... |
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TF0102 |
C-HEGA-11
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C-HEGA-11 is a useful organic compound for research related to life sciences. The catalog number is TF0102 and the CAS number is 864434-16-2. |
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T37935 |
16-phenoxy tetranor Prostaglandin F2α cyclopropyl methyl amide
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16-phenoxy tetranor Prostaglandin F2α cyclopropyl methyl amide |
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The actions of many clinical F-series prostaglandins (PGs), including those used for estrous synchronization and for reduction of intraocular pressure (IOP), are mediated through the PGF2α (FP) receptor. 16-phenoxy tetra... |
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T74460 |
c-Myc inhibitor 5
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c-Myc Inhibitor 5 (DA3) is a fluorescent bispurine compound with a long-chain bridge that selectively binds to the c-MYC G-quadruplex, exhibiting a dissociation constant (K D) of 16 μM. Unlike other G4-driven oncogenes, ... |
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T63590 |
c-Met-IN-10
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c-Met-IN-10 is a potent c-Met kinase inhibitor (IC50: 16 nM). c-Met-IN-10 inhibits the activity of cancer cells A549, H460 and HT-29, and inhibits A549 cell movement by inhibiting HT-29 cell colony formation, which in tu... |
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T76666 |
β-Amyloid peptide(16-20)
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β-Amyloid peptide(16-20), with the amino acid sequence (KLVFF) derived from Amyloid-β (Abeta), functions as an efficient inhibitor of Abeta fibril formation. This compound is modified with RG-/-GR-NH2 residues at both it... |
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T82805 |
Butaprost free acid
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(R)-Butaprost (free acid) is a prostaglandin E2 (PGE2) analog exhibiting high EP2 receptor subtype selectivity, commonly used to delineate EP receptor expression in human and animal tissues and cells. In 1986, Gardiner i... |
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T76516 |
HCV-1 e2 Protein (484-499)
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HCV-1 e2 Protein (484-499) is a 16-amino acid peptide derived from the envelope 2 protein of the hepatitis C virus, identified in the sera of individuals possessing antibodies to HCV [1]. |
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T36590 |
9-PAHSA
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Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprise... |
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T36586 |
12-PAHSA
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Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprise... |
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T79467 |
Antifungal agent 60
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Antifungal agent 60 (compound 16), a broad-spectrum ergosterol biosynthesis inhibitor, demonstrates potent activity against seven human pathogenic fungal species, including two fluconazole-resistant C. albicans isolates ... |
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T35533 |
6-Hydroxypyridin-3-ylboronic Acid
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6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block.1,2It has been used in the synthesis of non-nucleoside inhibitors of hepatitis C virus (HCV) RNA-dependent RNA polymerase nonstructural protein 5B (NS5B)... |
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T70798 |
Benastatin B
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Benastatin B is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; Ki = 3.7 µM for the rat liver enzyme).2 Bena... |
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T71382 |
KRC-108
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KRC-108 is a multiple kinase inhibitor. KRC-108 is a potent inhibitor of Ron, Flt3 and TrkA as well as c-Met. KRC-108 inhibited oncogenic c-Met M1250T and Y1230D more strongly than wild type c-Met. The anti-proliferative... |
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TP1604 |
Thioredoxin reductase peptide
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Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active disulfi... |
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T35902 |
Milbemycin A4 oxime
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Milbemycin A4 oxime is a derivative of milbemycin A4 and a component of milbemycin oxime , compounds that both have insecticidal and nematocidal activity. Milbemycin A4 oxime (0.05 mg/kg) reduces the number of microfilar... |
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T35987 |
CAY10563
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CAY10563 |
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S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low m... |
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T75989 |
Malantide TFA
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Malantide TFA, a synthetic dodecapeptide, originates from the phosphorylation site targeted by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Exhibiting a high specificity for PKA with a Mi... |
