|
T19672 |
Amtolmetin guacil
|
MED 15,MED15,ST679,ST-679,ST 679,MED-15 |
COX
|
|
Amtolmetin guacil (ST-679) inhibits prostaglandin synthesis and cyclooxygenase. Amtolmetin guacil has similar NSAID properties like tolmetin with additional analgesic, antipyretic, and gastroprotective properties. |
|
T66121 |
Ketoconazole Intermediate 1e
|
(cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate |
Others
|
|
Ketoconazole Intermediate 1e ((cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4- methylbenzenesulfonate) is a ketoconazole intermediate. |
|
T2524 |
Dexmedetomidine
|
|
Adrenergic Receptor
|
|
Dexmedetomidine is a Central alpha-2 Adrenergic Agonist. The mechanism of action of dexmedetomidine is as an Adrenergic alpha2-Agonist. The physiologic effect of dexmedetomidine is by means of General Anesthesia. |
|
T65554 |
Cholesterol-absorption inhibitor Intermediate 2
|
|
Others
|
|
cholesterol-absorption inhibitor Intermediate 2 is a potent and orally active cholesterol absorption inhibitor that reduces blood cholesterol levels. |
|
T40475 |
Ceftobiprole medocaril
|
BAL5788 |
Antibacterial
|
|
Ceftobiprole medocaril (BAL5788) is the parenteral prodrug of Ceftobiprole. Ceftobiprole is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA). |
|
T3979 |
Emedastine
|
LY188695,Emadine |
Histamine Receptor
|
|
Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its... |
|
T0977 |
Medrysone
|
Gimeracil,6α-Methyl-11β-hydroxyprogesterone |
Glucocorticoid Receptor
,
Others
|
|
Medrysone (6α-Methyl-11β-hydroxyprogesterone) is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with specific intracellular ... |
|
T5903 |
Sitagliptin Intermediate 2
|
|
|
|
Sitagliptin Intermediate 2 is a useful organic compound that has been used in life science related research. |
|
T19415 |
Medronic acid
|
Methylenediphosphonic acid |
Others
|
|
Medronic acid (Methylenediphosphonic acid), a methylene-substituted bisphosphonate, exhibits affinity for and adherence to hydroxyapatite crystals within the bone matrix. Accumulating at sites of osteoid mineralization, ... |
|
T24444 |
Medifoxamine
|
LG 152,Medifoxamina,LG-152,LG152 |
Dopamine Receptor
,
Monoamine Oxidase
|
|
Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.Medifoxamine preferentially inhibits dopamine reuptake. |
|
T6219 |
Azilsartan Medoxomil
|
TAK-491 |
RAAS
|
|
Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. |
|
TP1270L |
2:PN:US20040072744 SEQID:2 claimed protein acetate
|
2:PN:US20040072744 SEQID:2 claimed protein acetate(389572-87-6 free base) |
Others
|
|
2:PN:US20040072744 SEQID:2 claimed protein acetate is a synthetic peptide, used for the research of Down’s syndrome and schizophrenia. |
|
T11074 |
Dolutegravir intermediate-1
|
1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid,1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid |
HIV Protease
|
|
Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) is a new synthetic Dolutegravir intermediate. Dolutegravir is an integrase inhibitor develope... |
|
T67152 |
Dacomitinib Intermediate 2
|
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine |
Others
|
|
Dacomitinib Intermediate 2 (N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine) has anticancer activity and can be used to study lung cancer. |
|
TP1083L |
Neuromedin U (rat) acetate
|
|
Others
|
|
Neuromedin U, rat acetate is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy ... |
|
T8750 |
LX-4211 intermediate
|
|
Others
|
|
LX-4211 intermediate is a synthetic intermediate of LX-4211, a potent SGLT1/2 inhibitor used as an antidiabetic agent. |
|
T1518 |
Olmesartan Medoxomil
|
CS 866,Benicar |
RAAS
|
|
Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension. |
|
T68126 |
Pemedolac
|
Dexpemedolac |
COX
|
|
Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders. |
|
T38514 |
PMEDAP
|
|
Others
,
HIV Protease
|
|
PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP also has anti-murine cytomega... |
|
T9136 |
Nuclomedone
|
|
Others
|
|
Nuclomedone is a biochemicals. |
|
T70008 |
Bomedemstat ditosylate
|
|
|
|
Bomedemstat, also known as IMG-7289, is a lysine-specific histone demethylase 1 (LSD1) inhibitor with antineoplastic activity. Bomedemstat may be useful in the treatment of acute myeloid leukaemia, myelodysplastic syndro... |
|
T13809 |
P62-mediated mitophagy inducer
|
PMI |
Mitophagy
|
|
P62-mediated mitophagy inducer (PMI) is a regulator of mitophagy . |
|
TP1442 |
Neuromedin B
|
|
Endogenous Metabolite
|
|
Neuromedin B (NMB) is one of the bombesin (BN)-related peptides in mammals. It was originally purified from pig spinal cords, and it has been shown to be present in central nervous system as well as in gastrointestinal t... |
|
T20301 |
Phenmedipham
|
Fenmedifam,Kemifam,HSDB 1402 |
Others
|
|
Phenmedipham (Fenmedifam) is a herbicide commonly used in the growth of sugar beets and strawberries. |
|
T10884 |
CRAC intermediate 1
|
5-(S)-Fluorowillardiine |
Calcium Channel
|
|
CRAC intermediate 1 (5-(S)-Fluorowillardiine) is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors. |
|
T10885 |
CRAC intermediate 2
|
|
Others
,
Calcium Channel
|
|
CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis. |
|
T0317 |
Buflomedil hydrochloride
|
Buflomedil HCl,Fonzylane,Loftyl |
Adrenergic Receptor
|
|
Buflomedil hydrochloride (Fonzylane), a vasodilator, is used in therapy of claudication or the symptoms of the peripheral arterial disease. |
|
T8753 |
LX-2761 intermediate
|
|
Others
|
|
LX-2761 intermediate is a synthetic intermediate of LX-2761, a chemically stable and potent SGLT1/2 inhibitor. |
|
T22967 |
MEDICA16
|
MEDICA 16 |
GPR
,
Others
,
ATP Citrate Lyase
|
|
Free fatty acid 1 (FFA1/GPR40) receptor agonist |
|
T6466 |
Dexmedetomidine hydrochloride
|
Precedex,(+)-Medetomidine hydrochloride,(S)-Medetomidine hydrochloride,Dexmedetomidine HCl |
Adrenergic Receptor
|
|
Dexmedetomidine hydrochloride (Precedex) is an imidazole derivative that is an agonist of the adrenergic alpha-2 receptor. It is closely-related to MEDETOMIDINE, which is the racemic form of this compound. |
|
T6579 |
Medetomidine hydrochloride
|
MPV785,Medetomidine HCl,Domitor |
Adrenergic Receptor
|
|
Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor. |
|
TP1257L |
Adrenomedullin (AM) (22-52), human acetate
|
Adrenomedullin (AM) (22-52), human acetate（159899-65-7 Free base） |
CGRP Receptor
|
|
|
|
TP1085L |
Neuromedin N acetate(92169-45-4 free base)
|
Neuromedin N (rat, mouse, porcine, canine) acetate |
Dopamine Receptor
|
|
Neuromedin N acetate(92169-45-4 free base) is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.Neuromedin N is a potent modulator of d... |
|
T33583 |
Naldemedine
|
S-297995,S297995,Naldemedine,S 297995,S297,995,S 297,995,S297,995;Naldemedine,S-297,995 |
|
|
Naldemedine (S 297995) is a peripheral selective μ-opioid receptor antagonist being developed by Shionogi for the treatment of opioid-induced adverse reactions, including constipation, nausea, and vomiting. They are usua... |
|
T33271 |
Medrogestone
|
R-13615,AY-62022,Medrogesterone,Colpro,Prothil |
|
|
Medrogestone is progesterone that is already used in hormone replacement therapy to treat menopausal symptoms and in the treatment of gynaecological conditions. |
|
T68722 |
Dramedilol
|
|
|
|
Dramedilol is a β-blocker with peripheral vasodilative activity under development by ISF (SmithKline Beecham). |
|
T69743 |
MEDS433
|
|
|
|
MEDS433 is a dihydroorotate dehydrogenase inhibitor (IC50 1.2 nM). MEDS433 inhibited the in vitro replication of hCoV-OC43 and hCoV-229E, as well as of SARS-CoV-2, at low nanomolar range. Notably, the anti-SARS-CoV-2 act... |
|
T75201 |
5’-O-DMTr-5-MedC (Ac)-methyl phosphonamidite
|
|
|
|
5’-O-DMTr-5-MedC (Ac)-methyl phosphonamidite, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include inhibiting DNA synthesis... |
|
TP1085 |
Neuromedin N
|
Neuromedin N (rat, mouse, porcine, canine) |
|
|
Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects. |
|
T35858 |
Adrenomedullin (22-52) (human) (trifluoroacetate salt)
|
|
|
|
Adrenomedullin (22-52) is a C-terminal fragment of adrenomedullin (1-52) . In vitro, adrenomedullin (22-52) reduces basal corticosterone production in a mixture of rat adrenocortical and adrenomedulllary cells. It also r... |
|
TP1625 |
Adrenomedullin (11-50), rat
|
|
|
|
Adrenomedullin 11-50 rat is a peptide fragment of adrenomedullin that possesses systemic vasodilator activity at the level of calcitonin gene-related peptide-1 (CGRP1) receptor activation. Adrenomedullin and its peptide ... |
|
TP1490 |
Proadrenomedullin (1-20), human
|
|
|
|
Endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 251 nM). Also a noncompetitive nicotinic cholinergic antagonist. Inhibits nicotine-stimulated catecholamine secretion from PC12 cells in vitro, and from s... |
|
TP1488 |
Proadrenomedullin (45-92), human
|
|
|
|
Proadrenomedullin (45-92), human, a mid-regional fragment of proadrenomedullin (MR-proADM), comprises amino acids 45–92 of pre-proADM. |
|
T35597 |
Neuromedin U-23 (rat) (trifluoroacetate salt)
|
|
|
|
Neuromedin U-23 (NMU-23) is a neuropeptide involved in diverse biological processes, including smooth muscle contraction, energy homeostasis, and nociception.1It is an agonist of neuromedin-U receptor 1 (NMUR1; EC50= 0.1... |
|
T126070 |
Epimedokoreanoside I
|
|
|
|
Epimedokoreanoside I is a useful organic compound for research related to life sciences. The catalog number is T126070 and the CAS number is 130756-11-5. |
|
T24443 |
Medazomide
|
Medazomidum,L 1777,L1777,L-1777 |
|
|
Medazomide is a antispasmodic drug. |
|
T69192 |
Nivimedone Free Base
|
|
|
|
Nivimedone Free Base inhibits mediator release & capillary permeability. |
|
T21492 |
Medetomidine
|
|
|
|
Medetomidine (Domtor) is a potent, highly selective α2-adrenoceptor agonist, demonstrating Ki values of 1.08 nM for α2-adrenoceptors and 1750 nM for α1-adrenoceptors, indicating significant selectivity for α2 over α1 rec... |
|
T29961L |
Amedalin
|
|
|
|
Amedalin is a biochemical. |
|
T71482 |
Penclomedine
|
|
|
|
Penclomedine is an antineoplastic agent which alkylates and crosslinks DNA, resulting in DNA strand breaks and inhibition of DNA and RNA synthesis. |
