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カタログ番号 | 製品名 | 別名 | ターゲット |
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T72037 | Anti-Influenza agent 4 | Influenza Virus | |
Anti-Influenza agent 4 is a potent and selective inhibitor of influenza virus, inhibiting A/Parma and A/Roma strains with EC50s of 62 nM and 150 nM, respectively. | |||
T9124 | Laninamivir octanoate | CS-8958 | Influenza Virus |
Laninamivir octanoate (CS-8958) is a long acting influenza neuraminidase (NA) inhibitor which shows superior anti-influenza virus activity. | |||
T7785 | T-1105 | Influenza Virus | |
T-1105 is a broad-spectrum antiviral inhibitor. | |||
T83046 | Anti-Influenza agent 5 | Influenza Virus | |
Anti-Influenza agent 5 (Compound IIB-2), a chalcone-like derivative, serves as an influenza nuclear export inhibitor. It effectively inhibits oseltamivir-resistant strains and hinders viral proliferation by obstructing t... | |||
T60778 | Anti-Influenza agent 3 | ||
Anti-Influenza agent 3 (compound 11h) is a potent anti-influenza agent with low cytotoxicity for MDCK epithelial cells. Anti-Influenza agent 3 inhibits the M2 WT and S31N ion channel conductivity. Anti-Influenza agent 3 ... | |||
T8333 | Aurintricarboxylic acid | ATA,NSC-4056,NSC4056,NSC 4056 | Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase |
Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. | |||
T20500 | Salcomine | NSC32965,NSC-32965,NSC 32965 | Influenza Virus |
Salcomine (NSC-32965) shows anti-influenza virus activity. | |||
T16914 | SP187 | UV4,MON-DNJ | Others , Virus Protease , Influenza Virus |
SP187 (MON-DNJ) is a host-targeted iminosugar. It has anti-filovirus infection activity.SP187 is used for therapeutic use against influenza and dengue viruses. | |||
T6642 | Rimantadine | 1-Rimantadine | Influenza Virus |
Rimantadine (1-Rimantadine) (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM. | |||
T28443 | PPQ-581 | ||
PPQ-581 is an anti-influenza agent. PPQ-581 interrupts the crucial RNP trafficking, resulting in influenza replication inhibition, preventing virus-induced cytopathic effects. | |||
T13075 | T-705RTP | Others | |
T-705RTP is a selective and GTP-competitive of influenza virus RNA polymerase(IC50 of 0.14 μM and a Ki of 1.52 μM), has potent anti-influenza virus activity. | |||
T13075L | T-705RTP sodium | Others | |
T-705RTP sodium is a selective and GTP-competitive of influenza virus RNA polymerase(IC50 of 0.14 μM and a Ki of 1.52 μM), has potent anti-influenza virus activity. | |||
T77060 | Lesofavumab | ||
Lesofavumab (MHAB5553A) is a human IgG1κ anti- influenza B virus antibody [1] . | |||
T40267 | RdRP-IN-3 | ||
RdRP-IN-3, a potential anti-influenza drug candidate, functions by inhibiting the activity of RNA-dependent RNA polymerase (RdRp). | |||
T62059 | Influenza A virus-IN-6 | ||
Influenza A virus-IN-6 (compound 16j) is a potent and selective inhibitor of influenza A virus (IC 50= 3.88 μM, CC50= 36.64 μM). Influenza A virus-IN-6 exhibits anti-IAV activity with low cytotoxicity. | |||
T62888 | Influenza A virus-IN-7 | ||
Influenza A virus-IN-7 (compound 16r) is a potent, orally active inhibitor of influenza A virus (IC50: 3.43 μM, CC50>100 μM). Influenza A virus-IN-7 is an anti-IAV agent with low cytotoxicity and inhibits viral RNA trans... | |||
T74614 | PROTAC Hemagglutinin Degrader-1 | ||
PROTAC Hemagglutinin Degrader-1 (Compound V3) is a potent degrader of influenza hemaglutinin (HA), demonstrating a median degradation concentration of 1.44 μM and exhibiting broad-spectrum anti-influenza virus activity [... | |||
T60810 | Influenza virus-IN-2 | ||
Influenza virus-IN-2 (compound 19) has anti-influenza A virus activities that is a potent inhibitor of influenza virus with an CC 50 of 150.85 μM and EC 50 of 2.58 μM. Influenza virus-IN-2 concentration-dependently inhib... | |||
T60697 | Influenza virus-IN-1 | ||
Influenza virus-IN-1 (compound 14) exhibits anti-influenza A virus activities which is a potent inhibitor of influenza A virus with an CC 50 of >200 μM and EC 50 of 2.46 μM. Influenza virus-IN-1 exhibits a concentration ... | |||
T61904 | HSP90-IN-14 | ||
HSP90-IN-14 (compound 4) is an effective Hsp90 inhibitor (Kd=0.26 μM). In MDCK cells, HSP90-IN-14 showed anti-influenza virus activity, the EC50 against influenza A/H3N2, A/H1N1 and B virus was 2.6, 3.9 and 17 μM, respec... | |||
T38952 | Triperiden | ||
Triperiden is a chemical compound that serves as an inhibitor of influenza virus multiplication. Specifically, it exerts its antiviral activity by targeting the haemagglutinin of fowl plague virus (FPV) and inhibiting th... | |||
T61394 | Neuraminidase-IN-5 | ||
Neuraminidase-IN-5 (Compound 5b), a dihydrofurocoumarin derivative, acts as a potent neuraminidase (NA) inhibitor, exhibiting significant inhibition with an IC 50 of 0.02 μM. Given NA's role in influenza pathogenesis, th... | |||
T61509 | Neuraminidase-IN-8 | ||
Neuraminidase-IN-8 (Compound 6d) is a powerful inhibitor of neuraminidase, exhibiting a low half-maximal inhibitory concentration (IC50) of 0.027 μM and demonstrating significant anti-influenza activities [1]. | |||
T74806 | HAA-09 | ||
HAA-09, an orally administered compound, serves as a powerful anti-influenza agent by targeting the influenza PB2_cap binding domain. It possesses significant activity against influenza A virus, exhibiting an EC50 of 0.0... | |||
T72717 | Anti-IAV agent 1 | ||
Anti-IAV Agent 1-1a is an orally administered compound effective against the Influenza A virus (IAV), demonstrating inhibitory concentration 50 (IC50) values of 0.03 μM and 0.06 μM for the H1N1 strain and the Oseltamivir... | |||
T61217 | RSV-IN-3 | ||
RSV-IN-3 (Compound 1) serves as a dual inhibitor targeting both the respiratory syncytial virus (RSV) and influenza virus A (IAV), demonstrating anti-RSV efficacy with an EC50 of 32.70 μM [1]. | |||
T60910 | RSV-IN-4 | ||
RSV-IN-4 (Compound 2) has anti-RSV activity with EC50 of 11.76 μM. RSV-IN-4 is a respiratory syncytial virus (RSV) and influenza virus A (IAV) dual inhibitor [1]. | |||
T63233 | Neuraminidase-IN-10 | ||
Neuraminidase-IN-10 is a neuraminidase inhibitor that exhibits anti-influenza effects and is able to act on H1N1 (IC50: 2.6 nM), H5N1 (IC50: 5.1 nM) and H5N8 (IC50: 1.65 nM). | |||
T79444 | HA-IN-1 | Influenza Virus | |
HA-IN-1 (compound 5g), a high-affinity Hemagglutinin (HA) ligand, targets the trypsin cleavage site of HA to inhibit HA-mediated membrane fusion and decrease pulmonary virus titer in vivo. This compound emerges as a prom... | |||
T77158 | Diridavumab | ||
Diridavumab, a monoclonal anti-HA stalk antibody, stabilizes the prefusion HA structure, thereby inhibiting the pH-dependent fusion of cellular and viral membranes in endosomes. This property renders it useful for resear... | |||
T60939 | Neuraminidase-IN-6 | ||
Neuraminidase-IN-6 (Compound 5c) is a derivative of 1,3,4-triazole-3-acetamide. Neuraminidase-IN-6 is a potent neuraminidase inhibitor with an IC50 value of 0.11 μM. Neuraminidase (NA) is an ideal target for the anti-inf... | |||
T38340 | 10-Norparvulenone | ||
10-Norparvulenone is a fungal metabolite originally isolated fromMicrosphaeropsis.1It decreases viral sialidase activity in, and increases survival of, MDCK cells infected with the mouse-adapted influenza virus A/PR/8/34... | |||
T7911 | Arbidol | ||
Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir both suppresses virus propagation and modulates the expression of inf... | |||
T77009 | Firivumab | ||
Firivumab (CT-P22; CT120), a human IgG1 monoclonal antibody targeting influenza A virus hemagglutinin (Anti-IAV HA), demonstrates neutralization capabilities against multiple strains including H1N1, H5N1, H6N1, H6N2, H8N... | |||
T79567 | Antiviral agent 35 | Influenza Virus | |
Antiviral agent 35 (compound 4d) serves as a potent orally active inhibitor of the influenza virus, targeting early stages of viral replication. It suppresses influenza-induced ROS accumulation, autophagy, and apoptosis,... | |||
T71291 | EICAR | ||
EICAR is a drug which acts as an inhibitor of the enzyme IMP dehydrogenase. It is a nucleoside derivative which has both anti-cancer and antiviral effects, and was originally developed for the treatment of leukemia, but... | |||
T35686 | 3-Acetyl Betulinaldehyde | ||
3-Acetyl betulinaldehyde is a triterpene and derivative of the cholesterol biosynthesis inhibitor betulin that has been found inA. japonica.1It is an intermediate in the synthesis of 3-acetylbetulinic acid, as well as va... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN2331 | Eleutheroside B1 | Influenza Virus | |
Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits l... | |||
T2738 | Dehydroandrographolide | NOS , Influenza Virus | |
Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees. | |||
T2982 | Xanthone | Genicide,Xanthenone,Benzophenone oxide | Apoptosis , Others , Influenza Virus , Antibacterial , Antifungal |
Xanthone (Xanthenone) is currently used as ovicide for codling moth eggs and as a larvicide. | |||
T2957 | Arctigenin | (-)-Arctigenin | Apoptosis , MMP , Influenza Virus , Autophagy |
(-)-Arctigenin ((-)-Arctigenin) is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Arctigenin is a lignan found in certain plan... | |||
T6569 | Mimosine | Leucenine,NSC 69188,Leucenol,L-Mimosine | Others |
L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator. | |||
T13229 | Tunicamycin | Influenza Virus , Antibacterial , Antibiotic , Antifungal | |
Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT). Tunicamycin has antitumor activity, as well as anti-bacterial, anti-fungal, and anti-viral activity... | |||
T5S2059 | Glaucine | Calcium Channel , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , PDE | |
Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of h... | |||
T26288 | Clovamide | trans-Clovamide,N-trans-Caffeoy-L-dopa | Apoptosis , Influenza Virus , ROS , Antibacterial |
Trans-Clovamide (trans-Clovamide) is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.) Trans-Clovamide is a potent antioxidantand that has shown neuroprot... | |||
T3376 | Cynaroside | Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,Luteolin 7-glucoside | Others , Influenza Virus , DNA/RNA Synthesis |
Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation. | |||
TN2353 | 8-Hydroxyapigenin | Isoscutellarein | Antioxidant , Influenza Virus |
8-Hydroxyapigenin (Isoscutellarein) is a brassinaceous compound derived from the plant Scutellaria baicalensis with anti-inflammatory, antioxidant and anti-influenza virus activity. | |||
TN3120 | 5-Hydroxy-7-acetoxy-8-methoxyflavone | Histone Demethylase , Antiviral | |
5-Hydroxy-7-acetoxy-8-methoxyflavone is a flavonoid compound that inhibits lipid peroxidation and may have anti-influenza virus activity. | |||
T75675 | Nepasaikosaponin K | Antiviral | |
Nepasaikosaponin K is a small molecule compound isolated from Chaikosaponin root with anti-influenza and antiviral activity and can be used in the study of viral infections. | |||
TN2166 | Rupestonic acid | ERK , p38 MAPK , Influenza Virus , Nrf2 | |
Rupestonic acid is a compound in Artemisia rupestris L., a well-known traditional Uighur medicine for the treatment of colds. Rupestonic acid has an anti-influenza virus activity. | |||
T0875 | Acetylcysteine | N-Acetyl-L-cysteine,LNAC,NAC,N-Acetyl Cysteine | Apoptosis , TNF , Ferroptosis , Influenza Virus , Reactive Oxygen Species , ROS , Endogenous Metabolite |
Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis, can be used to reduce mucus thickness, and has anti-influenza viral activity. | |||
TN1051 | 1-Caffeoylquinic acid | NF-κB | |
1-Caffeoylquinic acid is an important intermediate in lignin biosynthesis. 1-Caffeoylquinic acid has anti-influenza, and antioxidant activities, it also slows the release of glucose into the bloodstream after a meal. | |||
T4S2126 | Ginkgetin | Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy | |
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ... | |||
T27380 | FR-198248 | ||
FR-198248, a new anti-influenza agent, shows antiinfluenza virus activity in Madin-Darby canine kidney (MDCK) cells in vitro. | |||
TN1066 | Filixic acid ABA | Influenza Virus | |
Filixic acid ABA exhibits inhibitory effects on neuraminidase of influenza virus H5N1 with IC50 as 29.57 ± 2.48 μM, it may have anti-influenza virus activity. | |||
TN1506 | Clemastanin B | Influenza Virus | |
Clemastanin B has antioxidant and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. | |||
TN5005 | Shegansu B | Influenza Virus | |
Shegansu B exhibits significant in vitro anti-influenza viral activity in MDCK cells. | |||
TN3461 | Asebotin | Influenza Virus | |
Asebotin shows anti-influenza A virus activity, it also possesses potent antiviral activity (100% inhibition at the concentration of 1 ug /mL) against highly pathogenic avian influenza strain H5N1. Asebotin can inhibit t... | |||
T36734 | Methyl brevifolincarboxylate | ||
Methyl brevifolincarboxylate (Brevifolincarboxylic acid methyl ester) is a potent influenza virus PB2 cap-binding inhibitor. Methyl brevifolincarboxylate exhibits inhibitory activity against influenza virus A/Puerto Rico... | |||
T8521 | Gnetin D | ||
Gnetin D exhibits significant in vitro anti-influenza viral activity in MDCK cells, with IC(50) values from 0.67 to 11.99 ug/mL. | |||
TN2311 | Wulignan A1 | Antifection | |
Wulignan A1 exhibits activity against leukemia P-388 in vitro; it also may have anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities. | |||
TN2176 | Sanggenol A | Influenza Virus , Antifection | |
TN6204 | Santin | 5,7-Dihydroxy-3,6,4'-trimethoxyflavone | Influenza Virus |
Santin (5,7-Dihydroxy-3,6,4'-trimethoxyflavone) is a flavonoid extracted from birch buds exerting antiproliferative, anti-influenza activity and anti-cancer activity. Santin can be used in studies about anti-IAV drugs. | |||
TN4392 | Koaburaside | IL Receptor , TNF , Influenza Virus | |
Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have anti-allergic inflammatory activity, it can suppress histam... | |||
TN1347 | 8-Prenylkaempferol | p38 MAPK , NF-κB , PI3K | |
8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction, it may be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated tran... | |||
T73465 | Goitrin | L-5-Vinyl-2-thiooxazolidone,(S)-Goitrin,(S)-Goitrin ; L-5-Vinyl-2-thiooxazolidone | |
Goitrin ((S)-Goitrin), formed through glucosinolate-myrosinase reactions, serves as a potent inhibitor of thyroid peroxidase, thereby hindering the thyroid's utilization of iodine. Additionally, it demonstrates anti-infl... | |||
TN4108 | Ganoderic acid Z | Antifection | |
The binding affinities of ganoderic acid DM and ganoderic acid Z (ÎGbind, -16.83 and-10.99 kcal mol-1) are comparable to that of current commercial drug oseltamivir (-23.62 kcal mol-1);Ganoderic acid DM is a potential s... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-02219 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) | H1N1 | E. coli |
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N... | |||
TMPJ-00527 | SP-D Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognitio... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L1700 | Anti-Viral Compound Library | 1040 compounds | |
A unique collection of 1040 anti-virus compounds effective for new anti-virus drugs high throughput screening and high content screening; | |||
L1800 | Anti-Infection Compound Library | 2938 compounds | |
A unique collection of 2938 anti-infective compounds including anti-bacterial, anti-fungi, anti-Human Cytomegalovirus (HCMV), anti-HIV, anti-SARS, anti-influenza, etc; | |||
L6730 | Anti-virus Traditional Chinese Medicine Monomer Library | 268 compounds | |
A collection of 268 TCM monomers with anti-virus activity. An effective tool for drug development and pharmacological studies. |