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Search Results for " diterpenoid "

阻害剤

天然化合物

カタログ番号	製品名	別名	ターゲット
T123808	Triptonoterpene
	Triptonoterpene is a natural product found in Tripterygium wilfordii and Tripterygium doianum. Triptonoterpene is an abietane diterpenoid.
T35346	Tiamulin fumarate	Thiamutilin fumarate	Antibacterial
	Tiamulin fumarate （Thiamutilin fumarate） is a semisynthetic diterpenoid antibiotic with antibacterial activity and inhibition of protein synthesis, which can be used to study pneumocystis.		Antibacterial
T32672	Leucothol B
	Leucothol B is a diterpenoid of Leucothoe grayana.
T32273	Jatrophatrione	NSC 254668,NSC254668,NSC-254668
	Jatrophatrione is a type of bioactive mesotricyclic diterpenoid.
T24195	Jatrophone	NSC-135037,NSC135037,Jatropha principle,NSC 135037
	Jatrophone is a novel inhibitor of the macrocyclic diterpenoid tumor.
T33157	Macrocalin B
	Macrocalin B is a diterpenoid against tumor cell proliferation and telomerase activity.
T34517	Sapriparaquinone
	Sapriparaquinone is a diterpenoid quinone that is isolated from the root of Salvia prionitis Hance.
T29787	Ajugamarin A 1
	Ajugamarin A 1 is a Neoclerodane diterpenoid.
T39353	8(14)-Abietenic acid
	8(14)-Abietenic acid, a racemic abietane diterpenoid, functions as a dual activator of PPARα/γ.
T32640	Lepedine
	Lepedine is a diterpenoid alkaloid extracted from the root of Aconitum psedohuiliense.
T71778	Pisiferic acid
	Pisiferic acid is a novel PP2C activator and an an antimicrobial diterpenoid
T33675	Nimbosone
	Nimbosone is a novel tricyclic diterpenoid.
T71312	Litophynin C
	Litophynin C is an Insect Growth Inhibitory Diterpenoid from a Soft Coral Litophyton sp.
T32409	Kobusine
	Kobusine is an aconite alkaloid of the C20-diterpenoid type.
T29711	Agastaquinone
	Agastaquinone, as a diterpenoid quinone, may have nonspecific cytotoxic activities against several human cancer cell lines in vitro.
T34458	Ryanodol
	Ryanodol is a complex diterpenoid that modulates intracellular calcium-ion release at ryanodine receptors, ion channels critical for skeletal and cardiac muscle excitation-contraction coupling and synaptic transmission.
T74064	Ent-Kaurene
	Ent-Kaurene, a diterpenoid, induces ROS (reactive oxygen species) accumulation by targeting antioxidant proteins and depleting GSH (glutathione), leading to apoptosis and ferroptosis [1].
T40563	Sandaracopimaric acid
	Sandaracopimaric acid is an anti-inflammatory diterpenoid compound that effectively reduces the contraction of phenylephrine-induced pulmonary arteries. With an EC50 of 43.93 μM, it exhibits noteworthy anti-inflammatory ...
T73950	Flutax-2 (5/6-mixture)
	Flutax-2 (5/6-mixture), an active fluorescent derivative of paclitaxel, binds to polymerized α,β tubulin dimers, with an excitation/emission wavelength of 496/524 nm. Derived from paclitaxel, a diterpenoid secondary meta...
T36668	Geranylgeranoic Acid
	Geranylgeranoic acid (GGA) is an isoprenoid that has been found inS. chinensisand has anticancer activity.1It induces apoptosis in Huh7 and PLC/PRF/5 human hepatoma cells and MLE-10 transformed mouse hepatocytes, but not...

Compounds

Synonym: Thiamutilin fumarate

Target: Antibacterial

Synonym: NSC 254668,NSC254668,NSC-254668

Target:

Jatrophone

T24195

Synonym: NSC-135037,NSC135037,Jatropha principle,NSC 135037

Sandaracopimaric acid

T40563

Synonym:

Target:

Flutax-2 (5/6-mixture)

カタログ番号	製品名	別名	ターゲット
TN4661	Nodosin		IL Receptor , Autophagy
	Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transp...		IL Receptor , Autophagy
TN4919	Rosthornin A		Others
	Rosthornin A is a kind of natural product derived from the herbs of Rabdosia rosthornii.		Others
TN5173	Trichorabdal A		Antifection
	Trichorabdal A shows a very strong in vitro antibacterial activity against Helicobacter pylori.		Antifection
TN4970	Sculponeatin B		Others
	Sculponeatin A is a natural product from Rabdosia amethystoides.		Others
T4S0590	Columbin		Phospholipase , COX , Parasite
	1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependent fashion.		Phospholipase , COX , Parasite
TN3967	Epieriocalyxin A		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
	Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
TN4920	Rosthornin B		Others
	Rosthornin B is a kind of natural product derived from the herbs of Rabdosia rosthornii.		Others
TN3273	8-Deacetylyunaconitine		Others
	8-Deacetylyunaconitine is a a diterpenoid alkaloid derived from Aconitum Vilmorinian Radix.		Others
T2S2018	7beta-Hydroxylathyrol	7β-Hydroxylathyrol,7-Hydroxylathyrol,7-beta-Hydroxylathyrol	P-gp
	7β-Hydroxylathyrol is a diterpenoid extract from the seed oil of Caper Spurge and displays P-gp inhibition resulting in cytotoxic properties.		P-gp
T13851	Pseudolaric Acid C2		Others
	Pseudolaric Acid C2 is a diterpenoid isolated from Pseudolarix kaempferi.		Others
T5765	Ranaconitine		Apoptosis , Others
	Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum Nakai,ranaconitine has cardiotoxicity.		Apoptosis , Others
TN4494	Maoecrystal B		Others
	Maoecrystal B is a diterpenoid isolated from the leaves of Isodon eriocalyx var.		Others
T5792	Rebaudioside M		Others
	Rebaudioside M is a natural non-calorie sweetener isolated from Stevia rebaudiana Bertoni,is a glycoside of the ent-kaurene diterpenoid aglycone.		Others
T9135	Epirosmanol		Others
	Epirosmanol is a diterpenoid containing a lactone moiety. Epirosmanol is a very weakly basic (essentially neutral) compound (based on its pKa).		Others
T4951	Kauran-16,17-diol		Apoptosis , Others
	Kauran-16,17-diol, a natural diterpenoid product, exhibits anti-tumoral and apoptosis-inducing activities by inhibiting NO production in LPS-induced RAW 264.7 cells with an IC50 value of 17 μM.		Apoptosis , Others
T1922	Pseudolaric Acid B		Apoptosis , p38 MAPK , Ferroptosis , HBV , Autophagy , Antifungal
	Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.
TN1754	Hypaconine		Others
	Hypaconine is a C19-diterpenoid alkaloid isolated from Aconitum and Delphinium spp. It exhibits strong cardiac activity.		Others
TN4375	Kamebanin		Antifection
	Kamebanin, a natural diterpenoid, has antibacterial activity. It also shows efficient cytotoxic activity against HeLa and HL-60 cells.		Antifection
T2790	Oridonin	NSC-250682,Rubescenin,Isodonol,Rubescensin A	Akt , Antibacterial
	Oridonin (NSC-250682) is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2.		Akt , Antibacterial
TQ0309	Glaucocalyxin B		Autophagy
			Autophagy
T2S1975	Ponicidin	Rubescensine B	Apoptosis , JAK , STAT
	Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens. Ponicidin exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer activity. Ponicidin induces apoptosis of gastric carcinoma ...		Apoptosis , JAK , STAT
T2179	Triptolide	PG490,NSC 163062	Apoptosis , Mdm2 , HSP , NF-κB
	Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation. Triptolide exhibits immunosuppressive, anti-rheumatic, anti-inflammatory, anti-proliferative and ...		Apoptosis , Mdm2 , HSP , NF-κB
T4S0536	Bullatine A		Apoptosis , P2X Receptor
	1. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects, may be used for the treatment of neurodegenerative diseases such as arthritis.		Apoptosis , P2X Receptor
T26029	Rabdosin A
	Rabdosin A is a diterpenoid antitumor constituent from Rabdosia japonica.
T30967	Clerodendrin	Clerodendrin (glycoside)
	Clerodendrin is a New Neoclerodane Diterpenoid.
T34248	Rabdoternin A	(-)-Rabdoternin A
	Rabdoternin A is a natural diterpenoid isolated from Rabdosia rubescen.
T82777	Carmichasine B
	Carmichasine B, a natural diterpenoid alkaloid, can be isolated from Aconitum carmichaelii [1].
T83180	Aconicarchamine B
	Aconicarchamine B, a C20-diterpenoid alkaloid, is isolated from Aconitum carmichaelii [1].
TN2365	Teucvidin	Teucvin	Others
	Teucvidin is a diterpenoid from Teucrium species		Others
T30156	Asebotoxin III
	Asebotoxin III is a diterpenoid obtained from the leaves of Asebi, Pieris japonica.
T80741	Zeylasterone
	Zeylasterone, a diterpenoid, is present in the plant Celastrus paniculatus [1].
T81220	Salvileucantholide
	Salvileucantholide, a diterpenoid extracted from Salvia leucantha [1], exhibits noteworthy pharmacological properties.
T75559	Rabdoserrin A
	Rabdoserrin A is a diterpenoid. Rabdoserrin A has antifungal activity [1] [2] .
T40784	Kansuinine E
	Kansuinine E, a jatrophane-type diterpenoid, is a plant-derived compound isolated from the roots of E. kansui. It functions as a nitric oxide inhibitor, with an inhibitory concentration of 6.3 μM (IC50).
T12787	Ryanodine		Others
	Ryanodine, a diterpenoid poison derived from Ryania speciosa, acts as a modulator of the ryanodine receptor, which is permeable to cells. Depending on its concentration, ryanodine can either stimulate or inhibit Ca2+ rel...		Others
T81044	Tanshinoic acid A
	Tanshinoic acid A, an oxidized tanshinone diterpenoid, is a derivative of 11,12-seco-tanshinone [1].
T80941	Triptonoterpene Me ether
	Triptonoterpene Me ether (compound 5), a rosinane-type diterpenoid, is derived from the traditional Chinese medicinal plant, Tripterygium wilfordii Hook. f [1].
T83279	6,7-Dehydrodugesin A
	6,7-Dehydrodugesin A, a neo-clerodane diterpenoid, can be isolated from the aerial parts of Salvia leucantha.[1]
T82457	Epinodosinol
	Epinodosinol, a diterpenoid isolated from the plant Rabdosia angustifolia, exhibits inhibitory activity against specific cancer cell lines [1].
T83426	1-Oxomicrostegiol
	1-Oxomicrostegiol, a diterpenoid extracted from the roots of Salvia viridis L. cvar, serves as a direct precursor to viroxocin [1].
T83216	Abiesadine F
	Abiesadine F, a diterpenoid, has been isolated from Abies georgei Orr [1].
T11509	Guanfu base H	Atisinium chloride	Others
	Guanfu base H is a diterpenoid alkaloid isolated from Aconitum coreanum. It has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 (IC50s: 4 μM and 3.6 μM).		Others
T82427	Euphoscopin C
	Euphoscopin C, a diterpenoid isolated from Euphorbia helioscopia, significantly enhances the cytotoxic activity of natural killer (NK) cells against H1299-luci and A549-luci cells [1].
T83291	5-Dexyexcoecafolin B
	5-Dexyexcoecafolin B, a tigliane-type diterpenoid extracted from Excoecaria acerifolia Didr. via EtOAc extraction, exhibits anti-HIV-1 activity and possesses an EC50 value of 0.036 μM [1].
T82429	Euphoheliosnoid A
	Euphoheliosnoid A (Compound 24), a diterpenoid, significantly enhances natural killer (NK) cell-mediated cytotoxicity against H1299-luci cells and A549-luci cells at a concentration of 2.5 μM [1].
T82590	Delcorine
	Delcorine, a C19-diterpenoid alkaloid, is isolated from the entire herb of Delphinium anthriscifolium var. savatieri [1].
T80763	Xerophilusin A
	Xerophilusin A, an ent-kaurane diterpenoid, is extractable from the aerial parts of Isodon enanderianus [1].
T82523	Dugesin B	(-)-Isosalvipuberulin,(-)-Isopuberulin
	Dugesin B ((-)-Isosalvipuberulin) is a rearranged clerodane diterpenoid isolated from the aerial parts of Salvia dugesii [1].
T81221	Salvileucalin A
	Salvileucalin A, a neo-clerodane diterpenoid, is extracted from the aerial parts of Salvia leucantha. [1]
T83359	3-epi-Tilifodiolide
	3-epi-Tilifodiolide, a neo-clerodane diterpenoid, can be isolated from the aerial parts of Salvia leucantha. [1]
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