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カタログ番号	製品名	別名	ターゲット
T11515	Gut restricted-7	GR-7	Potassium Channel
	Gut restricted-7 (GR-7) (GR-7) is a covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. It decreases gut bacterial BSHs and decreases deconjugated bile acid levels in the feces of mice.		Potassium Channel
T3124	Carbendazim	Bavistin,Carbendazole,Mercarzole	Antifungal
	Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspec...		Antifungal
T13385	Zamifenacin fumarate	UK-76654 fumarate	AChR
	Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.		AChR
T76944	Cergutuzumab amunaleukin
	Cergutuzumab amunaleukin (CEA-IL2v), a monomeric immunocytokine, targets carcinoembryonic antigen (CEA) and is based on an IL-2 variant. It exhibits immunostimulating and antineoplastic activities.
T77071	Lonigutamab
	Lonigutamab (hz208F2-4), a humanized monoclonal antibody targeting IGF-1R, facilitates the creation of antibody-drug conjugates (ADC) [1].
T30747	Cargutocin	Y-5350,Y 5350,Y5350
	Cargutocin is a biochemical.
T76977	Timigutuzumab
	Timigutuzumab (GEXMab73) is a humanized monoclonal antibody designed to target ErbB2, showing potential application in cancer research [1].
T83297	5'6-FAM-UUCUCCGAACGUGUCACGUTT, ACGUGACACGUUCGGAGAATT
	5'6-FAM-UUCUCCGAACGUGUCACGUTT, ACGUGACACGUUCGGAGAATT is a fluorescein (FAM)-labeled oligonucleotide, denoted by the sequence provided.
T1242	Alvimopan		Opioid Receptor
	Alvimopan (LY 246736) is a synthetic trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid...		Opioid Receptor
T35898	Izencitinib
	Izencitinib (TD-1473) is an orally active, gut-restricted JAK inhibitor with non-selective properties. It is primarily employed in the investigation of ulcerative colitis [1].
T25984	Prenalterol	H80/62,H-80/62,H 80/62
	Prenalterol is a selective β1-adrenergic receptor agonist. Prenalterol has no effect on gut smooth muscle contractile activity. Prenalterol has potential to be used for researching cardiovascular disease [1].
TP1059	Peptide YY (PYY) (3-36), human	Peptide YY (3-36)	Neuropeptide Y Receptor
	Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.		Neuropeptide Y Receptor
T1053	Mebeverine hydrochloride	Colofac Hydrochloride,Duspatalin Hydrochloride,Duspatal Hydrochloride	Others , Sodium Channel
	Mebeverine hydrochloride (Colofac Hydrochloride), a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gut.		Others , Sodium Channel
T10623	BSH-IN-1		Potassium Channel
	BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM and 427 nM for B. longum BSH and B. theta BSH).		Potassium Channel
T15500	HPi1		Others , Antibacterial
	HPi1 is a selective and orally active antimicrobial against Helicobacter pylori (IC50: 0.24 μM and a MIC of 0.08-0.16 μg/mL). HPi1 is inactive against other Xaliproden, including the gut commensals, Lactobacillus reuteri...		Others , Antibacterial
TP1083L	Neuromedin U (rat) acetate		Others
	Neuromedin U, rat acetate is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy ...		Others
T3162	IDE1		Others
	IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50: 125.5 nM...		Others
T21327	Uridine triacetate	RG 2133 triacetate,PN-401,Tri-O-acetyluridine,PN401,RG 2133,RG-2133,PN 401,RG2133,RG2133 triacetate	Others
	Uridine triacetate (RG 2133 triacetate) (Tri-O-acetyl uridine), an orally active prodrug of uridine, is efficiently absorbed in the gut and swiftly deacetylated in the circulation to release free uridine. It is utilized ...		Others
T1600	Doxifluridine	Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine	Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by...		Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
TP2309	NEUROTENSIN TFA (39379-15-2 free base)	Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH TFA（55508-42-4 free base),NEUROTENSIN TFA	Others
	Neurotensin TFA (39379-15-2 free base) is an endogenous 13 amino acid neuropeptide with profound opioid-independent analgesic effects. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a...		Others
T15778	LP-533401		Hydroxylase
	LP-533401 is an inhibitor of Tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut.		Hydroxylase
T17283	Zamifenacin	UK-76654	Others
	Zamifenacin obviously decreases colonic motility in irritable bowel syndrome. Zamifenacin is an effective gut-selective muscarinic M3 receptor antagonist.		Others
TP1084	Neuromedin U, rat TFA (117505-80-3 free base)	Neuromedin U (rat) (TFA),Rat neuromedin U-23 TFA,Neuromedin U, rat TFA
	Neuromedin U, rat TFA is a 23-amino acid brain-gut peptide.
T35403	(±)-Equol 4'-sulfate (sodium salt)
	(±)-Equol 4’-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol .[1] It has been used as a standard for the quantification of unconjugated equol in rat plasma.[2]
T35374L	(Ala13)-Apelin-13 acetate		Apelin receptor
	(Ala13)-Apelin-13 acetate, an APJ antagonist, modulates CRF-induced enhanced colonic motility, visceral sensation, and gut barrier.		Apelin receptor
TP1058	Peptide YY (PYY) (3-36), human TFA	Peptide YY (3-36) (TFA)
	Peptide YY (PYY) (3-36), human (TFA) is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite[1].
T75773	Peptide YY (PYY) (3-36), porcine TFA
	Peptide YY (PYY) (3-36), porcine TFA, functions as a gut hormone that serves as a Y2 receptor agonist, effectively reducing appetite [1].
TP1083	Neuromedin U, rat	Rat neuromedin U-23,Neuromedin U (rat)
	Neuromedin U,a 23-amino acid brain-gut peptide, regulates several important physiological functions through its cognate receptor NMUR2 in the central nervous system, including energy balance, stress response, and nocicep...
T74465	Colibactin
	Colibactin, a complex secondary metabolite synthesized by certain genotoxic Escherichia coli strains in the gut, holds potential for colorectal cancer research [1].
TP1831	[Nle11]-Substance P
	[Nle11]-Substance P is a substance P analog that avoids methionine oxidation problems. Substance P was found in the gut as well as in the brain. It is responsible for a number of excitatory effects on both central and pe...
T37854	Cholic Acid 7-sulfate
	Cholic acid 7-sulfate is a metabolite of the primary bile acid cholic acid.[1],[2] It is produced by conjugation of a sulfate group with the hydroxy group at position 7 of cholic acid in the liver and gut. Fecal levels o...
T79774	Antibacterial agent 159		Antibiotic
	Compound 6d (Antibacterial agent 159) is an antibiotic effective against impetigo and Clostridium difficile infection (CDI), with no observed recurrence for CDI and minimal impact on the beneficial gut microbiome [1].		Antibiotic
T37809	Alphitonin
	Alphitonin is a flavonoid that has been found in L. leptolepis wood.1 It is also a metabolic intermediate that is formed during the catabolism of quercetin by the human gut bacteria E. ramulus.2,3 \|1. Chen, K., Ohmura, W...
T74985	MRV03-037
	MRV03-037, a selective colibactin-activated peptidase (ClbP) inhibitor, effectively inhibits the genotoxic effects of Colibactin on eukaryotic cells by blocking the production of gut bacterial genotoxins [1].
T78004	Neuromedin U, rat TFA	Rat neuromedin U-23 TFA,Neuromedin U (rat) (TFA)
	Neuromedin U (rat TFA), a 23-amino acid brain-gut peptide, operates via its specific receptor NMUR2 in the central nervous system to modulate critical physiological processes such as energy homeostasis, stress response, ...
T38072	HSGN-218
	HSGN-218 is a gut-restrictive antibiotic.1It is active againstC. difficile(MIC = 0.007 μg/ml) and clinical isolates ofC. difficile(MICs = 0.003-0.03 μg/ml) and is not cytotoxic to Caco-2 cells when used at concentrations...
T81025	Teduglutide TFA	ALX-0600 TFA
	Teduglutide TFA, a dipeptidyl peptidase IV-resistant glucagon-like peptide-2 (GLP-2) analogue, exhibits trophic effects on the gut mucosa and is used in research related to short bowel syndrome (SBS) and Crohn's disease ...
T77154	Etrolizumab
	Etrolizumab (rhuMAb Beta7), a gut-selective anti-β7 integrin monoclonal antibody, targets the β7 subunit of α4β7 and αEβ7 integrins specifically, demonstrating affinity with K i values of 18 nM for Human α4β7 and 1800 pM...
T35631	Peptide YY (human) (trifluoroacetate salt)	Peptide Tyrosine Tyrosine
	Peptide YY (PYY) is a 36-amino acid peptide and anorectic gut hormone agonist for the neuropeptide Y receptors Y1, Y2, Y5, and Y6 with EC50 values of 0.7, 0.58, 1, and 0.8 nM, respectively, for supression of forskolin-in...
T70267	ADL 08-0011 HCl
	ADL 08-0011 is an active metabolite of the μ-opioid receptor antagonist alvimopan. It is produced from alvimopan via amide hydrolysis by gut microbiota. ADL 08-0011 is a μ-opioid receptor antagonist (Ki = 0.25 nM). It is...
T82600	DDAO-C6
	DDAO-C6, a cridone ester derivative, serves as a highly specific fluorescent probe for detecting human serum albumin (HSA). Additionally, it functions as an enzymatically activatable near-infrared fluorescent probe, faci...
T35460	β-Endorphin (rat)
	β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities. It is produced via piomelanocortin cleavage in the pituitary gland, hypothalamus, and in lymphocytes, then migrates to its sites...
T70506	Bupranolol HCl
	Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity. Its potency is similar to propranolol. Bupranolol is quickly and completely abso...
T36660	Olsalazine-13C6	Olsalazine-13C6
	Olsalazine-13C6is intended for use as an internal standard for the quantification of olsalazine by GC- or LC-MS. Olsalazine is an orally bioavailable prodrug form of the anti-inflammatory agent 5-aminosalicylic acid that...
T35980	Bilirubin Conjugate (sodium salt)
	Bilirubin conjugate is a stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives. In vivo, bilirubin circulates in the plasma and is taken up by hepatocytes and...
T83955	MOMBA
	MOMBA is a selective orthosteric agonist specifically targeting engineered human free fatty acid 2 (hFFA2) receptors, particularly those modified as designer receptors activated by designer drugs (DREADD). It demonstrate...
T14382	AZD7687		Others
	AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 value of 80 nM (hDGAT1). IC50 value: 80 nM [1] Target: DGAT1 in vitro: Plasma AZD7687 exposure was measured repeatedly. AZD7687 markedly reduced postprandial...		Others

Compounds

Gut restricted-7

T11515

Synonym: GR-7

Target: Potassium Channel

Carbendazim

T3124

Synonym: Bavistin,Carbendazole,Mercarzole

Target: Antifungal

Zamifenacin fumarate

T13385

Synonym: UK-76654 fumarate

Target: AChR

Cergutuzumab amunaleukin

Synonym: Y-5350,Y 5350,Y5350

5'6-FAM-UUCUCCGAACGUGUCACGUTT, ACGUGACACGUUCGGAGAATT

Target: Opioid Receptor

Synonym: H80/62,H-80/62,H 80/62

Target:

Peptide YY (PYY) (3-36), human

TP1059

Synonym: Peptide YY (3-36)

Target: Neuropeptide Y Receptor

Mebeverine hydrochloride

T1053

Synonym: Colofac Hydrochloride,Duspatalin Hydrochloride,Duspatal Hydrochloride

Target: Others, Sodium Channel

BSH-IN-1

T10623

Synonym:

Target: Potassium Channel

HPi1

T15500

Synonym:

Target: Others, Antibacterial

Neuromedin U (rat) acetate

Synonym: RG 2133 triacetate,PN-401,Tri-O-acetyluridine,PN401,RG 2133,RG-2133,PN 401,RG2133,RG2133 triacetate

Target: Others

Doxifluridine

T1600

Synonym: Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

NEUROTENSIN TFA (39379-15-2 free base)

TP2309

Synonym: Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH TFA（55508-42-4 free base),NEUROTENSIN TFA

Neuromedin U, rat TFA (117505-80-3 free base)

TP1084

Synonym: Neuromedin U (rat) (TFA),Rat neuromedin U-23 TFA,Neuromedin U, rat TFA

Target:

(±)-Equol 4'-sulfate (sodium salt)

T35403

Synonym:

Target:

(Ala13)-Apelin-13 acetate

T35374L

Synonym:

Target: Apelin receptor

Peptide YY (PYY) (3-36), human TFA

TP1058

Synonym: Peptide YY (3-36) (TFA)

Target:

Peptide YY (PYY) (3-36), porcine TFA

Synonym: Rat neuromedin U-23,Neuromedin U (rat)

Cholic Acid 7-sulfate

T37854

Synonym:

Target:

Antibacterial agent 159

Neuromedin U, rat TFA

T78004

Synonym: Rat neuromedin U-23 TFA,Neuromedin U (rat) (TFA)

Synonym: ALX-0600 TFA

Peptide YY (human) (trifluoroacetate salt)

T35631

Synonym: Peptide Tyrosine Tyrosine

Synonym: Olsalazine-13C6

Target:

Bilirubin Conjugate (sodium salt)

カタログ番号	製品名	別名	ターゲット
TN7108	Urolithin C		Apoptosis , Calcium Channel , Reactive Oxygen Species , IGF-1R , Endogenous Metabolite
	Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
T4S0554	Theaflavine-3,3'-digallate	TFBG,theaflavin digallate	Others
	1. Theaflavine-3,3'-digallate (theaflavin digallate) and lactic acid together could reduce herpes simplex virus transmission.		Others
TN6796	2'-FUCOSYLLACTOSE	2'-Fucosyl-D-lactose	Others
	2'-FUCOSYLLACTOSE (2'-Fucosyl-D-lactose) is a fucose-containing oligosaccharide.		Others
TN5755	Guttiferone G
	Guttiferone G is a natural product for research related to life sciences. The catalog number is TN5755 and the CAS number is 666174-75-0.
T19408	M-Coumaric acid		Endogenous Metabolite
	m-Coumaric acid, a polyphenol metabolite derived from caffeic acid, is produced by gut microflora. Its presence in human biofluids varies with diet.		Endogenous Metabolite
T8878	Urolithin M6	3,8,9,10-tetrahydroxy urolithin	Others
	urolithin M6 (3,8,9,10-tetrahydroxy urolithin) (UM6) is an ellagitannin metabolite produced by gut microbiota, was identified as a putative galloflavin mimetic		Others
T8071	L-Lysine hydrochloride	Lysine hydrochloride	Virus Protease
	L-Lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, reducing diabetes-related illnesses, increasing calcium absorption and improving gut health.		Virus Protease
T4722	O-Acetyl-L-serine hydrochloride		Others , Endogenous Metabolite
	O-Acetylserine (OASS) is an acylated amino acid derivative. It is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants. Its presence in humans arises from either microbial metaboli...		Others , Endogenous Metabolite
T3840	Dihydroresveratrol	3,4',5-Trihydroxybibenzyl	Estrogen Receptor/ERR , Others
	Dihydroresveratrol (3,4',5-Trihydroxybibenzyl) is a major metabolite of resveratrol that is produced by animal-associated bacteria, including the gut microbiota. Dihydroresveratrol and dihydroresveratrol monosulfate are ...		Estrogen Receptor/ERR , Others
TN6733	Kansuiphorin C	KPC	Others
	Kansuiphorin C (KPC) is a natural product with a number of bioactivity. KPC could ameliorate malignant ascites by modulating gut microbiota mainly containing the increase of Lactobacillus and the decrease of Helicobacter...		Others
T4840	3-Hydroxybenzoic acid		Others , Endogenous Metabolite
	Produced in the gut microflora as one of the three main metabolites formed from the catechin diet. Its use in the production of glycol benzoates for the application of plasticizer in adhesive formulations is increasing. ...		Others , Endogenous Metabolite
T2A2428	2-Hydroxy-4-methoxybenzoic acid	2-Hydroxy-p-anisic Acid,4-Methoxysalicylic acid	Others
	2-Hydroxy-4-methoxybenzoic acid (2-Hydroxy-p-anisic Acid) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 3-(2-hydroxy-4-methoxyphenyl)propanoic acid. It is generated by unspe...		Others
T3737	3-(2,4-Dihydroxyphenyl)propanoic acid	Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid	Tyrosinase
	3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 3-(2, 4-dihydroxyphenyl)prop-2-enoic acid. It is generated by abkar1...		Tyrosinase
T4875	Palatinose hydrate	6-O-α-D-Glucopyranosyl-D-fructose, Isoma	Others , Endogenous Metabolite
	Palatinose hydrate (6-O-α-D-Glucopyranosyl-D-fructose, Isoma) is a disaccharide having an α(1→6) linkage between D-glucose and D-fructose and is similar to sucrose in its physicochemical properties. It is produced from s...		Others , Endogenous Metabolite
TN1237	3-O-Methylgallic acid	3,4-Dihydroxy-5-methoxybenzoic acid	Apoptosis , NF-κB , OCT , DNA/RNA Synthesis , STAT
	3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation ...		Apoptosis , NF-κB , OCT , DNA/RNA Synthesis , STAT
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T4889	2,6-Diaminoheptanedioic acid		Others , Endogenous Metabolite
	Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall. DAPA is incorporated or integrated into peptidoglycan of gram negative bacteria and is the attachment...		Others , Endogenous Metabolite
T36585	Isodeoxycholic Acid	isoDCA	Chloride channel , Antibacterial
	Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less...		Chloride channel , Antibacterial
T5089	5-Aminovaleric acid		Others , Endogenous Metabolite
	5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is formed via the following multi-step reaction:...		Others , Endogenous Metabolite
T37404	O-Desmethylangolensin
	O-Desmethylangolensin is a gut microbiota metabolite of daidzein, a soy isoflavone. It demonstrates antioxidant activity[1][2].
T83804	5-(3'-Hydroxyphenyl)-γ-Valerolactone	(3’-hydroxy)-PVL,δ-(3’-Hydroxyphenyl)-γ-VL,5-(3’-Hydroxyphenyl)-γ-VL,δ-(3’-Hydroxyphenyl)-γ-Valerolactone
	5-(3'-Hydroxyphenyl)-γ-valerolactone, a metabolite resulting from the transformation of polyphenols such as (+)-catechin and (−)-epicatechin by gut microbiota, plays a significant role in biological processes.
T37710	5-Hydroxyoxindole		Reactive Oxygen Species
	5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activit...		Reactive Oxygen Species
T77988	Phenyl sulfate	Phenyl hydrogen sulfate	Endogenous Metabolite
	Phenyl sulfate, an orally active metabolite derived from gut microbiota, induces albuminuria and podocyte damage in diabetes experimental models. It serves as a potential disease marker and therapeutic target for diabeti...		Endogenous Metabolite
T83673	4-Hydroxyphenylpropionylglycine	Phloretylglycine,4-hydroxy PPG,Phloretic Acid Glycine Conjugate
	4-Hydroxyphenylpropionylglycine, a metabolite derived from the conditionally essential amino acid tyrosine, is synthesized through a process involving aromatic amino acid aminotransferase and tyrosine aminotransferase ac...

天然物製品

Urolithin C

TN7108

Synonym:

Target: Apoptosis, Calcium Channel, Reactive Oxygen Species, IGF-1R, Endogenous Metabolite

Theaflavine-3,3'-digallate

T4S0554

Synonym: TFBG,theaflavin digallate

Target: Others

2'-FUCOSYLLACTOSE

TN6796

Synonym: 2'-Fucosyl-D-lactose

Target: Endogenous Metabolite

urolithin M6

T8878

Synonym: 3,8,9,10-tetrahydroxy urolithin

Target: Others

L-Lysine hydrochloride

T8071

Synonym: Lysine hydrochloride

Target: Virus Protease

O-Acetyl-L-serine hydrochloride

T4722

Synonym:

Target: Others, Endogenous Metabolite

Dihydroresveratrol

T3840

Synonym: 3,4',5-Trihydroxybibenzyl

Target: Estrogen Receptor/ERR, Others

3-Hydroxybenzoic acid

T4840

Synonym:

Target: Others, Endogenous Metabolite

2-Hydroxy-4-methoxybenzoic acid

T2A2428

Synonym: 2-Hydroxy-p-anisic Acid,4-Methoxysalicylic acid

Target: Others

3-(2,4-Dihydroxyphenyl)propanoic acid

T3737

Synonym: Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid

Target: Tyrosinase

Palatinose hydrate

T4875

Synonym: 6-O-α-D-Glucopyranosyl-D-fructose, Isoma

Target: Others, Endogenous Metabolite

3-O-Methylgallic acid

TN1237

Synonym: 3,4-Dihydroxy-5-methoxybenzoic acid

Target: Apoptosis, NF-κB, OCT, DNA/RNA Synthesis, STAT

Urolithin B

T13265

Synonym:

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

2,6-Diaminoheptanedioic acid

T4889

Synonym:

Target: Others, Endogenous Metabolite

Isodeoxycholic Acid

T36585

Synonym: isoDCA

Target: Chloride channel, Antibacterial

5-Aminovaleric acid

T5089

Synonym:

Target: Others, Endogenous Metabolite

O-Desmethylangolensin

T37404

Synonym:

Target:

5-(3'-Hydroxyphenyl)-γ-Valerolactone

T83804

Synonym: (3’-hydroxy)-PVL,δ-(3’-Hydroxyphenyl)-γ-VL,5-(3’-Hydroxyphenyl)-γ-VL,δ-(3’-Hydroxyphenyl)-γ-Valerolactone

Target: Reactive Oxygen Species

Phenyl sulfate

T77988

Synonym: Phenyl hydrogen sulfate

Target: Endogenous Metabolite

4-Hydroxyphenylpropionylglycine

T83673

Synonym: Phloretylglycine,4-hydroxy PPG,Phloretic Acid Glycine Conjugate

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00261	TGF beta 2 Protein, Mouse/Rat, Recombinant	Mouse,Rat	HEK293 Cells
	Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci...
TMPH-02608	Corticoliberin Protein, Mouse, Recombinant (His & KSI)	Mouse	E. coli
	Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile.
TMPH-02823	Peptide YY/PYY Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
TMPH-03247	Artemin Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of...
TMPH-01852	Peptide YY/PYY Protein, Human, Recombinant (GST)	Human	E. coli
	This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Peptide YY/PYY Protein, Human, Recombinant (GST) is expressed in E. coli expression syste...
TMPJ-00479	KHK Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Ketohexokinase, also known as Hepatic fructokinase, is a member of the carbohydrate kinase PfkB family. It exits as a homodimer and most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adren...
TMPK-01137	FAM3D Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (m...
TMPH-02239	TMPRSS4 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.; (Microbial infection) In gut epithelia...
TMPJ-00500	Kappa-Casein Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Kappa-Casein (CSN3) is a secreted protein that belongs to the Kappa-Casein family. CSN3 exists in heteromultimers that are composed of alpha-s 1casein and kappa casein linked by disulfide bonds. CSN3 is involved in a nu...
TMPJ-00079	IL-11 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate ...
TMPJ-00771	TGF beta 1 Protein, Mouse/Rat, Recombinant	Mouse,Rat	HEK293 Cells
	Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen...
TMPY-03438	Calsequestrin 1 Protein, Human, Recombinant	Human	E. coli
	Calsequestrin-1 is an isoform of calsequestrin. Calsequestrin is a calcium-binding protein of the sarcoplasmic reticulum. It helps hold calcium in the cisterna of the sarcoplasmic reticulum after a muscle contraction,...
TMPY-01360	FGFRL1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Fibroblast growth factor receptor-like 1 (FGFRL1) also known as Fibroblast growth factor receptor 5 (FGFR5), is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserv...
TMPY-01654	ITCH Protein, Human, Recombinant (aa 526-903)	Human	E. coli
	E3 ubiquitin-protein ligase Itchy homolog, also known as Atrophin-1-interacting protein 4, NFE2-associated polypeptide 1, NAPP1, and ITCH, is a cell membrane protein that contains one C2 domain, one HECT (E6AP-type E3 ub...
TMPH-02690	PLA2G10 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatid...

TGF beta 2 Protein, Mouse/Rat, Recombinant

TMPJ-00261

Species: Mouse,Rat

Expression System: HEK293 Cells

Corticoliberin Protein, Mouse, Recombinant (His & KSI)

TMPH-02608

Species: Mouse

Expression System: E. coli

Peptide YY/PYY Protein, Mouse, Recombinant (GST)

TMPH-02823

Species: Mouse

Expression System: E. coli

Artemin Protein, Rat, Recombinant (His & Myc)

TMPH-03247

Species: Rat

Expression System: E. coli

Peptide YY/PYY Protein, Human, Recombinant (GST)

TMPH-01852

Species: Human

Expression System: E. coli

KHK Protein, Human, Recombinant (His)

TMPJ-00479

Species: Human

Expression System: HEK293 Cells

FAM3D Protein, Human, Recombinant (hFc)

TMPK-01137

Species: Human

Expression System: HEK293 Cells

TMPRSS4 Protein, Human, Recombinant (His & Myc)

TMPH-02239

Species: Human

Expression System: E. coli

Kappa-Casein Protein, Human, Recombinant (His)

TMPJ-00500

Species: Human

Expression System: HEK293 Cells

IL-11 Protein, Mouse, Recombinant (hFc)

TMPJ-00079

Species: Mouse

Expression System: HEK293 Cells

TGF beta 1 Protein, Mouse/Rat, Recombinant

TMPJ-00771

Species: Mouse,Rat

Expression System: HEK293 Cells

Calsequestrin 1 Protein, Human, Recombinant

TMPY-03438

Species: Human

Expression System: E. coli

FGFRL1 Protein, Mouse, Recombinant (His)

TMPY-01360

Species: Mouse

Expression System: HEK293 Cells

ITCH Protein, Human, Recombinant (aa 526-903)

TMPY-01654

Species: Human

Expression System: E. coli

PLA2G10 Protein, Mouse, Recombinant (His & Myc)

TMPH-02690

Species: Mouse

Expression System: E. coli

カタログ番号	製品名
L2540	Gut Microbial Metabolite Library	607 compounds
	A unique collection of 607 gut microbial metabolites which can be used for HTS and HCS;
L6600	Anti-Gastroenteritis Natural Product Library	219 compounds
	A unique collection of 219 natural products related to gastroenteritis for high throughput screening (HTS) and high content screening (HCS);

ライブラリー

Gut Microbial Metabolite Library

L2540

Compounds: 607

Anti-Gastroenteritis Natural Product Library

L6600

Compounds: 219