| T3S0175 |
Gardenia yellow
|
alpha-Crocin,Crocin I,Crocine |
Sirtuin
|
|
Gardenia yellow (Crocin I) has anti atherosclerosis and hypolipidemic effects. |
| T2756 |
Swertiamarin
|
Swertiamaroside |
Others
|
|
Swertiamarin (Swertiamaroside) is a common secoiridoid found among the members of Gentianaceae with anti-inflammatory, anticancer, hypoglycemic and hypolipidemic activities. |
| T5311 |
Crocin (Gardenia Fruits Extract)
|
|
Others
|
|
Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L.). Crocin has anti-inflammatory, anti-oxidative, anti-apoptotic, anti-asthma, anti-cancer, and hypolipidemic effects. |
| T5707 |
3-O-Methylgalangin
|
3-Methylgalangin,GALANGIN-3-METHYLETHER |
Antibacterial
|
|
3-O-Methylgalangin (GALANGIN-3-METHYLETHER) has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. GALANGIN-3-METHYLETHER has hypolipidemic activity, the action is due to the inhibition of pancr... |
| T5690 |
7,4'-Di-O-methylapigenin
|
4',7-DIMETHOXY-5-HYDROXYFLAVONE |
Amylase
|
|
7,4'-Di-O-methylapigenin (4',7-DIMETHOXY-5-HYDROXYFLAVONE) can inhibit α-glucosidase and α-amylase enzymes and enhance 2-NBDG uptake in L6 cells, it has hypolipidemic effect on mouse pre-adipocyte (3T3L1) cell lines. |
| T2840 |
Phloracetophenone
|
2,4,6-trihydroxyacetophenone,1-(2,4,6-Trihydroxyphenyl)ethanone |
Others
,
P450
,
Antibacterial
,
Antibiotic
|
|
Phloracetophenone (1-(2,4,6-Trihydroxyphenyl)ethanone) has antiobesity and hypolipidemic effects, may be partly mediated by delaying the intestinal absorption of dietary fat by inhibiting pancreatic lipase activity. |
| T5431 |
[10]-Shogaol
|
10-Shogaol |
Antioxidant
,
COX
|
|
[10]-Shogaol (10-Shogaol) is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects. |
| T0687 |
Simvastatin
|
MK-0733,MK 733 |
Apoptosis
,
Mitophagy
,
Ferroptosis
,
HMG-CoA Reductase
,
Autophagy
|
|
Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovasc... |
| T3884 |
Neoandrographolide
|
Neoandrographiside |
NOS
,
COX
|
|
Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iN... |
| T8189 |
Dihydroberberine
|
|
Potassium Channel
,
HSP
,
HER
|
|
Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interacti... |
| T4749 |
Squalene
|
Nikko Squalane EX,Super Squalene,AddaVax,all-trans-Squalene,trans-Squalene,Spinacene |
Reactive Oxygen Species
,
Endogenous Metabolite
,
Antifungal
|
|
Squalene (AddaVax) is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil, though there are botanical sources as well, including rice bran, wheat germ, and olives. All hi... |
| TN4138 |
Globularin
|
|
Others
|
|
Globularin has hypoglycaemic and hypolipidemic activities in normal and streptozotocin-induced diabetic rats. |
| TN1868 |
Ligupurpuroside A
|
|
LDL
,
AMPK
|
|
Ligupurpuroside A has antioxidant,and hypolipidemic effects, it can significantly inhibit lipid accumulation in HepG2 cell at the concentration of 50 μMol/L. |
| TN1462 |
Cajanin
|
|
ERK
,
MEK
,
Akt
|
|
Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol efflux and RCT, it can significantly improve basal glucose up... |
| TN6613 |
Delphinidin-3-O-galactoside chloride
|
|
|
|
Delphinidin-3-O-galactoside chloride has anti-obesity and hypolipidemic effects. Delphinidin-3-O-galactoside (D3G) is a water-soluble anthocyanin with antioxidant activity. D3G is capable of masking the EGCG-induced cyto... |
| T11202 |
Enniatin complex
|
|
Others
|
|
Enniatin complex, a mixture of cyclohexadepsipeptides predominantly derived from various Fusarium species of fungi, exhibits inhibitory effects on enzymes such as acyl-CoA: cholesterol acyl transferase. Furthermore, it h... |
| TN5431 |
Icariside E4
|
|
Antioxidant
,
AMPK
,
Liver X Receptor
,
Lipid
,
Fatty Acid Synthase
|
|
Icariside E4 is a natural compound derived from Ulmus minor that acts via AMPK phosphorylation and inhibition of MID1IP2 hypolipidation in HepG1 cells.Icariside E4 has anti-injurious, antioxidant, anti-Alzheimer's and an... |
| T36563 |
(E)-Guggulsterone
|
|
|
|
Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulat... |
