|
T15017 |
CU-T12-9
|
|
TLR
|
|
CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activat... |
|
T1237 |
Azathioprine
|
BW 57-322 |
Apoptosis
,
GPR
,
Rho
|
|
Azathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation. |
|
T7222 |
GS-441524
|
GS 441524 triphosphate |
Others
,
SARS-CoV
,
DNA/RNA Synthesis
|
|
GS-441524 treatment of cats with naturally occurring feline infectious peritonitis. |
|
T9567 |
Samatasvir
|
ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719 |
HCV Protease
|
|
Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A. |
|
T40019 |
Thalidomide-5-NH2-CH2-COOH
|
|
Others
|
|
Thalidomide-5-NH2-CH2-COOH (compound 114) is a selective inhibitor of the protomyosin receptor kinase. It is a ligand for E3 ligase and has potential for studying one or more diseases. |
|
T4990 |
Cefcapene pivoxil hydrochloride hydrate
|
Cefcapene Pivoxil Hydrochloride |
Antibacterial
,
Antibiotic
|
|
Cefcapene pivoxil hydrochloride hydrate is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity. After oral administration of cefcapene pivoxil, the es... |
|
T16465 |
Penicillin G benzathine
|
Benzathine benzylpenicillin,Benzathine penicilline G |
Antibacterial
|
|
Penicillin G benzathine has anti-bacterial infectious activity and can be used to study early syphilis. |
|
T26804 |
Biclotymol
|
|
Others
|
|
Biclotymol is used in the study about infectious oropharyngeal diseases. |
|
T72910 |
APOBEC3G-IN-1
|
|
Others
|
|
APOBEC3G-IN-1 (MN136.0185) is a targeted APOBEC3G inhibitor with anti-HIV activity for the study of infectious diseases and cancer. |
|
T8686 |
VUN65671
|
|
Others
|
|
Compounds 35 are superior inhibitors of Ebola (Mayinga) and Marburg (Angola) infectious viruses. |
|
T78748 |
MtUng-IN-1
|
|
Antibacterial
|
|
MtUng-IN-1 (Compound 18a) inhibits mycobacterial uracil DNA glycosylase (MtUng) with an IC50 value of 300 μM. MtUng-IN-1 is suitable for use in cancer and infectious disease research. |
|
T14044 |
4E2RCat
|
|
PERK
|
|
|
|
T11815 |
Lanopepden
|
GSK 1322322,GSK-1322322B,GSK-1322322J |
Antibiotic
|
|
Lanopepden (GSK 1322322) is a potent peptide deformylase inhibitor of Staphylococcus aureus, inhibiting ATCC 29213 and ATCC 25923 strains, and can be used in the study of pneumonia, dermatological and infectious diseases... |
|
T76687 |
Ibalizumab
|
TNX-355,TMB-355 |
HIV Protease
|
|
Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4 receptor.Ibalizumab has anti-HIV-1 infectious activity and m... |
|
T6229 |
Daclatasvir
|
Daklinza,EBP 883,BMS-790052 |
HCV Protease
|
|
Daclatasvir (EBP 883) (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3. |
|
T38894 |
IHVR-17028
|
|
Influenza Virus
,
Glucosidase
|
|
IHVR-17028 is a potent broad-spectrum ERα-glucosidase I (α-glucosidase? I) inhibitor with IC50 of 0.24 μM and antiviral activity. IHVR-17028 inhibited BVDV, TCRV and DENV, and EC50 values were 0.4 μM, 0.26 μM and 0.3 μM,... |
|
T60440 |
Antiviral agent 17
|
|
|
|
Antiviral agent 17 (Compound 4) is an anti-infection agent that retains its strong antiviral effect in a human replicon assay with an EC50 of 0.015 μM. Antiviral agent 17 shows good antiviral activity against murine noro... |
|
T76251L |
Ac-FEID-CMK TFA
|
|
Pyroptosis
|
|
Ac-FEID-CMK TFA is a selective zebrafish GSDMEb-derived peptide inhibitor that reduces mortality and renal injury in infectious shock.Ac-FEID-CMK TFA inhibits pyroptosis in vivo, attenuates septic AKI (acute kidney injur... |
|
T0454L |
Florfenicol
|
SCH-25298,(-)-Florfenicol |
Antibacterial
,
Antibiotic
|
|
Florfenicol (SCH-25298), a fluorinated synthetic analog of thiamphenicol, is currently indicated for the therapy of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Haemophilus somnu... |
|
T28330 |
PD 135390
|
PD135390,PD-135390 |
|
|
PD 135390 is a HIV-1 protease inhibitors identified by rational selection. Inactivation of the protease prevents infectious virion formation. |
|
T28329 |
PD 134922
|
PD134922,PD-134922 |
|
|
PD 134922 is a HIV-1 protease inhibitors. Inactivation of the protease prevents infectious virion formation. |
|
T61523 |
FWM-5
|
|
|
|
FWM-5 is a powerful inhibitor of NSP13 helicase, a key enzyme in the life cycle of the SARS-CoV-2 virus. With its potential in researching infectious diseases, FWM-5 emerges as a promising compound [1]. |
|
T60875 |
Polvitolimod
|
|
|
|
Polvitolimod is a TLR7 agonist used to treat infectious disease and cancer. |
|
T63406 |
HCV-IN-35
|
|
|
|
HCV-IN-35 is a potent inhibitor of HCV and shows potential for infectious disease research. |
|
T61591 |
SARS-CoV-2-IN-20
|
|
|
|
SARS-CoV-2-IN-20 (Compound 1a) is a highly effective inhibitor of SARS-CoV-2, displaying an impressive EC50 value of 6.5 μM. With its exceptional inhibitory properties, SARS-CoV-2-IN-20 holds great potential for advancin... |
|
T70050 |
Boditrectinib
|
|
|
|
Boditrectinib, a potent tyrosine kinase inhibitor, functions as an antineoplastic agent and is valuable in researching cancer, inflammation, neurodegenerative diseases, and certain infectious diseases. |
|
T40211 |
EIF4E-IN-1
|
eIF4E-IN-1 |
|
|
eIF4E-IN-1 (WO2021003194A1, compound Y), is a highly effective inhibitor of eIF4E, a key protein involved in immunosuppression. By targeting immune checkpoint proteins such as PD-1, PD-L1, LAG3, TIM3, and IDO, eIF4E-IN-1... |
|
T61860 |
Enpp-1-IN-9
|
|
|
|
Enpp-1-IN-9, a powerful inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (ENPP1), exhibits wide substrate specificity, capable of cleaving various bonds such as phosphodiester bonds of nucleotides and nucl... |
|
T81943 |
Lemalesomab
|
IMMU-MN3 |
|
|
Lemalesomab (IMMU-MN3), a mouse IgG1 monoclonal antibody targeting NCA-90, comprises a Fab' fragment and is utilized in the study of inflammation, infectious lesions, and infection imaging [1]. |
|
TP1362 |
Angiogenin (108-122)
|
Angiogenin 108-122 |
|
|
Angiogenin (108-122) is an angiogenin peptide. Angiogenin (108-122) acts as a therapeutic agent for the prophylaxis and/or treatment of cancer, an infectious disease, a fibrotic disease, an inflammatory disease, a neurod... |
|
TP1320 |
Angiogenin (108-122) TFA (112173-49-6 free base)
|
Angiogenin (108-122) TFA |
|
|
Angiogenin (108-122) TFA is an angiogenin peptide.Angiogenin (108-122) acts as a therapeutic agent for the prophylaxis and/or treatment of cancer, an infectious disease, a fibrotic disease, an inflammatory disease, a neu... |
|
T76321 |
Brain Derived Basic Fibroblast Growth Factor (1-24)
|
|
|
|
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24), a synthetic peptide, exhibits anti-bacterial and anti-HBV properties, finding application in infectious and immune disease research [1]. |
|
T60673 |
Antiviral agent 18
|
|
|
|
Antiviral agent 18 (Compound 5) shows good antiviral activity against murine norovirus. Antiviral agent 18 is an anti-infection agent that has the potential in infectious and malignant diseases research [1]. |
|
T25365 |
EGA
|
|
Others
|
|
EGA inhibits the intoxication of lethal toxins and prevents the entry of a variety of other acid-dependent bacterial toxins and viruses into mammalian cells.EGA is a powerful tool for the study of membrane trafficking an... |
|
T75166 |
Influenza virus-IN-7
|
|
|
|
Influenza virus-IN-7 (Example 16) is an orally active inhibitor of cap-dependent endonuclease, employed in research on influenza viral infectious diseases [1]. |
|
T69657 |
GS-441524 HCl
|
|
|
|
GS-441524 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an EC50 of 0.78 μM.. GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infecti... |
|
T63888 |
Axl-IN-12
|
|
|
|
Axl-IN-12 is a potent inhibitor of AXL. Axl-IN-12 can be used to study proliferative, allergic, autoimmune, inflammatory, cancer, transplant rejection, viral infectious diseases or other mammalian diseases. |
|
T62341 |
(R)-Larotrectinib
|
|
|
|
(R)-Larotrectinib is a potent inhibitor of TRK and acts on TrkA (IC50: 28.5 nM). (R)-Larotrectinib can be used to study cancer, inflammation and certain infectious diseases. |
|
T73416 |
BiCAPPA
|
|
|
|
BiCAPPA, a pioneering bivalent antiprion ligand, effectively reduces the infectious conformational form of prion protein (PrP Sc) in scrapie-infected cells, achieving this at a concentration (EC 50) of 0.32 μM. |
|
T69925 |
NVR3-778 hydrate
|
|
|
|
NVR 3-778 is the first capsid assembly modulator (CAM) that has demonstrated antiviral activity in hepatitis B virus (HBV)-infected patients. NVR 3-778 inhibited the generation of infectious HBV DNA-containing virus part... |
|
T63537 |
SARS-CoV-2 3CLpro-IN-1
|
|
|
|
SARS-CoV-2 3CLpro-IN-1 (Compound 14c) is a highly potent inhibitor specifically designed to target and inhibit the activity of SARS-CoV-2 3CL pro, which is a cysteine-protease found in the main coronaviruses. This partic... |
|
T11819 |
Lascufloxacin
|
KRP-AM1977X |
Others
|
|
Lascufloxacin, a potent and orally active fluoroquinolone antibacterial agent, holds potential for the treatment of various infectious diseases, including lower respiratory tract infections. It effectively inhibits infec... |
|
T81388 |
Propiolactone
|
Betaprone,β-propiolactone,2-Oxetanone |
SARS-CoV
|
|
Propiolactone (β-propiolactone; 2-Oxetanone), a chemosterilant, effectively inactivates viruses, rendering them non-infectious. It has been utilized at a 1:1000 (v:v) ratio alongside SARS-CoV to create the BPL-inactivate... |
|
T62903 |
Enpp-1-IN-6
|
|
|
|
Enpp-1-IN-6 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). Enpp-1-IN-6 has the potential to be used in cancer and infectious disease research. |
|
T63683 |
Axl-IN-11
|
|
|
|
Axl-IN-11 is a potent inhibitor of AXL. Axl-IN-11 can be used to study proliferative diseases, allergic diseases, autoimmune diseases, inflammatory diseases, cancer, transplant rejection, viral infectious diseases or oth... |
|
T63607 |
PD-1/PD-L1-IN-22
|
|
|
|
PD-1/PD-L1-IN-22 is a small molecule inhibitor of PD-1/PD-L1 protein-protein interactions that blocks PD-1/PD-L1 interactions (IC50: 0.732 μM). PD-1/PD-L1-IN-22 can be used to study cancer, infectious diseases and autoim... |
|
T76526 |
Ac-D-DGla-LI-Cha-C
|
|
|
|
Ac-D-DGla-LI-Cha-C is a potent peptide inhibitor of the HCV protease, applicable in research targeting a range of diseases, including cancer, autoimmune, fibrotic, inflammatory, neurodegenerative, infectious, lung, heart... |
|
T64086 |
PD-1/PD-L1-IN-20
|
|
|
|
PD-1/PD-L1-IN-20 is a small molecule inhibitor of PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-20 blocks the PD-1/PD-L1 interaction (IC50: 5.29 nM). PD-1/PD-L1-IN-20 can be used to study cancer, infectious disea... |
|
T63950 |
SARS-CoV-2-IN-19
|
|
|
|
SARS-CoV-2-IN-19 is a potent inhibitor of SARS-CoV-2 (EC50: 8.8 μM). SARS-CoV-2-IN-19 is effective against SARS-CoV-2 decapping enzyme (nsp13), a highly conserved enzyme that exhibits potential against emerging HCoV outb... |
|
T79929 |
L-Methionine γ-lyase
|
Methionine lyase |
|
|
L-Methionine γ-lyase (Methionine lyase), a multifaceted enzyme in the γ-family of pyridoxal-5’-phosphate (PLP)-dependent enzymes, catalyzes the α, γ-elimination of L-methionine and homocysteine. This enzyme exhibits anti... |
