|
T9925 |
Ofatumumab
|
|
Others
|
|
Ofatumumab is a fully human monoclonal antibody to CD20 which appears to inhibit early-stage B lymphocyte activation |
|
T9915 |
Eculizumab
|
|
Complement System
|
|
Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5 |
|
T9921 |
Infliximab
|
|
TNF
|
|
Infliximab is a humanized antibody against tumor necrosis factor α TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis. |
|
T9927 |
Panitumumab
|
|
EGFR
|
|
Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR). |
|
T9962 |
Mepolizumab
|
SB 240563 |
IL Receptor
|
|
Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5. Mepolizumab can be used in studies about severe eosinophilic asthma and eosinophilic granulomatosis with polyangiitis. |
|
T9922 |
Matuzumab
|
|
EGFR
|
|
Matuzumab is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR frequently associated with the growth of blood vessels in malignancy facilitating tumor growth and survival. |
|
T76769 |
Indusatumab
|
|
Guanylate cyclase
|
|
Indusatumab (5F9 Monoclonal antibody) is an anti-human GUCY2C (Guanylate cyclase 2C) monoclonal antibody that can be used to synthesize antibody-drug conjugate. |
|
T77480 |
Bivatuzumab
|
BIWA 4 |
Others
|
|
Bivatuzumab (BIWA 4) is a humanized monoclonal antibody against CD44v6. |
|
T9913 |
Ustekinumab
|
|
Interleukin
|
|
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody. |
|
T76891 |
Oxelumab
|
Ro 49-89991,R 4930,huMAb OX 40L |
Interleukin
|
|
Oxelumab (R 4930) is a human monoclonal antibody for OX40L. Oxelumab could be used to study asthma. |
|
T77374 |
Ontuxizumab
|
MORAb-004 |
Others
|
|
Ontuxizumab (MORAb-004) is a monoclonal antibody targeting endomelanic acid with anti-tumor effects.Ontuxizumab is a potent IgG1/κ anti-endothelin (TEM-1 or CD248) monoclonal antibody for the treatment of metastatic mela... |
|
T77385 |
Idactamab
|
INT-001 |
|
|
Idactamab (INT-001) is a monoclonal antibody to the human amino acid transport protein ASCT2. |
|
T77099 |
Nimacimab
|
JNJ 2463,RYI-018 |
Others
|
|
Nimacimab is a recombinant humanized monoclonal antibody. It can improve diabetes and non-alcoholic steatohepatitis. |
|
T9901 |
Adalimumab
|
|
TNF
|
|
Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha. |
|
T9903 |
Avelumab
|
|
PD-1/PD-L1
|
|
Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity. |
|
T76975 |
Tomaralimab
|
OPN-305 |
TLR
|
|
Tomaralimab (OPN-305) is a humanized IgG4 monoclonal antibody targeting TLR2. Tomarlimab is used to study myelodysplastic syndromes (MDS). |
|
T9904 |
Bevacizumab
|
|
VEGFR
|
|
Bevacizumab, a humanized monoclonal antibody, specifically and with high affinity binds to all isoforms of VEGF-A. |
|
T77399 |
Crizanlizumab
|
ADAKVEO,SEG-101 |
Others
|
|
Crizanlizumab (Adakveo) is a humanized monoclonal antibody against P-selectin for the prevention of pain crises in sickle cell disease. |
|
T76744 |
Enokizumab
|
MEDI-528 |
IL Receptor
|
|
Enokizumab (MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma. |
|
T77018 |
Garadacimab
|
CSL312 |
Factor Xa
|
|
Garadacimab (CSL312) is a potent whole-human IgG4 monoclonal antibody targeting activation factor XII (FXIIa). Garadacimab can be used to study hereditary angioedema. |
|
T9917 |
Denosumab
|
|
RANKL/RANK
|
|
Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand |
|
T77426 |
Pascolizumab
|
SB-240683 |
IL Receptor
|
|
Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis. |
|
T76777 |
Bermekimab
|
MABp1 |
IL Receptor
|
|
Bermekimab (MABp1) is a humanized monoclonal antibody against interleukin-1α (IL-1α).Bermekimab has potential anti-inflammatory activity to prevent skin inflammation. |
|
T9924 |
Obinutuzumab
|
Obinutuzumab/afutuzumab |
Others
|
|
Obinutuzumab (Obinutuzumab/afutuzumab) GA101) is a glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma. |
|
T76888 |
Quetmolimab
|
E-6011,KANAb 001 |
Others
|
|
Quetmolimab is a humanized monoclonal antibody targeting chemokine ligand 1 (CX3CL1) that can be used to study rheumatoid arthritis. |
|
T29087 |
VA-K-14 hydrochloride
|
VAK14 Hydrochloride,VA K 14 HCl,VA-K-14 HCl,VAK14 HCl |
TSH Receptor
|
|
VA-K-14 hydrochloride（VAK14 HCl） is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogate... |
|
T77407 |
Ensituximab
|
NPC-1C,NEO-102,NEO-101 |
|
|
Ensituximab (NEO-102) is a quasi-selective IgG1 monoclonal antibody against the MUC5AC variant with anti-tumour activity that inhibits colorectal and pancreatic cancer. |
|
T76706 |
Varlilumab
|
CDX-1127 |
TNF
|
|
Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors. |
|
T76874 |
Erenumab
|
AMG-334 |
CGRP Receptor
|
|
Erenumab is a whole-human monoclonal antibody. Erenumab inhibits calcitonin gene-related peptide (CGRP) receptors. Erenumab can be used to prevent migraine attacks. |
|
T9926 |
Omalizumab
|
|
Others
|
|
Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE) |
|
T9914 |
Vedolizumab
|
|
Integrin
|
|
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis. |
|
T78339 |
Human IgG4 (S228P) kappa, Isotype Control
|
|
|
|
Human IgG4 (S228P) kappa Isotype Control is a human-mouse chimeric monoclonal antibody serving as an isotype control specifically for the human IgG4 (S228P)κ antibody. |
|
T77406 |
Lorvotuzumab
|
|
Others
|
|
Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) is a humanized monoclonal antibody that binds to CD56 (NCAM1). Lorvotuzumab can be used to synthesize antibody-drug conjugate (Lorvotuzumab mertansine). |
|
T76702 |
Sutimlimab
|
|
Complement System
|
|
Sutimlimab is a novel monoclonal antibody targeting complement protein C1. Sutimlimab is commonly used as a C1 inhibitor to treat cold agglutina-associated hemolysis. |
|
T77132 |
Clesrovimab
|
MK-1654 |
Others
|
|
Clesrovimab (MK1654) is an anti-respiratory syncytial virus protein F human monoclonal antibody for the prevention and treatment of respiratory syncytial virus infections. |
|
T77416 |
Opicinumab
|
BIIB033 |
Others
|
|
Opicinumab (BIIB033) is a novel monoclonal antibody against LINGO-1 that may be used to prevent and delay acute optic neuritis and recurrent multiple sclerosis. |
|
T14578 |
Biotin Hydrazide
|
|
Others
|
|
Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe. Biotin Hydrazide is a great choice for labeling mouse monoclonal antibodies, lectins, sugars, unpaired cytosine residues in nuclei... |
|
T9906 |
Ipilimumab
|
|
Others
|
|
Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor. |
|
T76937 |
Burfiralimab
|
hzVSF-v13 |
HBV
|
|
Burfiralimab (hzVSF-v13) is a monoclonal immunoglobulin (IgG4) directed against waveform proteins that
has anti-HBV effects and can be used to study rheumatoid arthritis, |
|
T77747 |
Adecatumumab
|
MT 201 |
Others
|
|
Adecatumumab (MT201) is a whole-person IgG1 monoclonal antibody to human EpCAM. Adecatumumab has potential anticancer activity and can be used to study breast cancer. |
|
T77748 |
Tusamitamab
|
|
Others
|
|
Tusamitamab is an IgG1 monoclonal antibody targeting CEACAM5 and is the naked antibody to Tusamitamab ravtansine.Tusamitamab can be used to synthesize the antibody-activator coupling Tusamitamab ravtansine. |
|
T76763 |
Teplizumab
|
PRV-031,MGA-031 |
Others
|
|
Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes. |
|
T76684 |
Girentuximab
|
cG250,WX-G250,G250 |
Carbonic Anhydrase
|
|
Girentuximab (G250) is a potent anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anticancer activity for the study of uroepithelial carcinoma PET (ZiPUP). |
|
T76742 |
Emapalumab
|
NI-0501 |
COX
|
|
Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab ha... |
|
T77448 |
Naxitamab
|
Naxitamab-gqgk,Humanized 3F8,Hu3F8 |
Others
|
|
Naxitamab (Hu3F8) is a humanized monoclonal antibody against GD2 (hu3F8). Naxitamab has antitumor activity and can be used to study neuroblastoma, osteosarcoma, and other GD2-positive cancers. |
|
T77129 |
Belantamab
|
GSK2857914 |
TNF
|
|
Belantamab (GSK2857914) is a humanized IgG1 monoclonal antibody against BCMA (TNFRSF17). Belantamab is a naked antibody to Belantamab mafodotin and can be used to synthesize antibody-active molecule conjugates (Belantama... |
|
T77369 |
Telazorlimab
|
ISB-830,GBR-830 |
Immunology/Inflammation related
|
|
Telazorlimab (GBR-830) is a humanized monoclonal antibody that targets the OX40 co-stimulatory receptor on activated T cells. Telazorlimab can be used to treat lupus erythematosus and atopic dermatitis. |
|
T9918 |
Daratumumab
|
|
Others
|
|
Daratumumab is a human monoclonal antibody that targets CD38 a cell surface protein that is overexpressed on multiple myeloma MM) cells. |
|
T77471 |
Tinurilimab
|
BAY 1834942 |
|
|
Tinurilimab (Bay 1834942) is a monoclonal antibody that targets and inhibits CEACAM6, an immune checkpoint regulator. Tinurilimab can be used in studies about effector T-cells against tumors. |
|
T77750 |
Rosmantuzumab
|
OMP-131R10 |
Others
|
|
Rosmantuzumab (OMP-131R10) is a humanized monoclonal antibody against R-spondin 3 (RSPO3). Rosmantuzumab has potential antitumor activity and can be used to study advanced relapsed refractory solid tumors. |
