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カタログ番号	製品名	別名	ターゲット
T9343	N-Cbz-DL-tryptophan		cholecystokinin
	N-Cbz-DL-tryptophan is a cholecystokinin receptor antagonist, abolished the response of the isolated heart to CCK-8.		cholecystokinin
T7694	6-fluoro-DL-Tryptophan		5-HT Receptor
	6-fluoro-DL-Tryptophan is an inhibitor of serotonin (5-HT) synthesis.		5-HT Receptor
T5489	Tryptophan, N-indol-3-ylacetyl- (6CI)	N-(3-Indolylacetyl)-L-tryptophan,Indole-3-acetyl-L-tryptophan	Glucosidase
	Tryptophan, N-indol-3-ylacetyl- (6CI) (Indole-3-acetyl-L-tryptophan) is involved in regulatory mechanisms for the control of auxin activity during physiological and pathophysiological responses. It may also be used in th...		Glucosidase
T38112	DL-Tryptophan octyl ester (hydrochloride)
	Tryptophan is an amino acid precursor of serotonin and melatonin. DL-Tryptophan octyl ester is a tryptophan derivative with an octyl ester protected COOH group. This addition creates a stable, cell-permeable molecule cap...
T33801	O-Nitrophenylsulfenyl-lysyl-tryptophan
	o-Nitrophenylsulfenyl-lysyl-tryptophan is a bioactive chemical.
TN7093	N-Caffeoyltryptophan	trans-Caffeoyl-L-tryptophan	Sirtuin
	N-Caffeoyltryptophan (trans-Caffeoyl-L-tryptophan), a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).		Sirtuin
T11449L	Golotimod	Gamma-D-glutamyl-L-tryptophan,SCV 07	Antibiotic
	Golotimod (SCV 07) is an antimicrobial dipeptide with immunomodulatory activity that significantly improves the efficacy of anti-tuberculosis therapy, induces thymic and splenic cell proliferation, modulates macrophage f...		Antibiotic
T2038	RG108	N-Phthalyl-L-tryptophan	DNA Methyltransferase
	RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).		DNA Methyltransferase
T20540	N-Valyltryptophan	Val-trp,L-Valyl-L-tryptophan	Others
	N-Valyltryptophan (Val-trp) is an incomplete breakdown product of protein catabolism or protein digestion.		Others
T6543	Indoximod	NLG-8189,Indoximod (NLG-8189）,1-Methyl-D-tryptophan	Indoleamine 2,3-Dioxygenase (IDO)
	Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan...		Indoleamine 2,3-Dioxygenase (IDO)
T22251	680C91		Others
	680C91 is a potent and selective inhibitor of TDO, and its Ki is 51 nM.		Others
T21506	Telotristat		Hydroxylase
	Telotristat is the active metabolite of LX1606(Telotristat etiprate), which is an orally bioavailable tryptophan hydroxylase (TPH) inhibitor and shows potential antiserotonergic activity.		Hydroxylase
T15796	LX-1031		Hydroxylase , LPA Receptor
	LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.		Hydroxylase , LPA Receptor
T4410	LM10		Others
	Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters....		Others
T125055	N-Malonyl DL-tryptophan
	N-Malonyl DL-tryptophan is a useful organic compound for research related to life sciences and the catalog number is T125055.
T33323	Methionyltryptophan	Met-trp,Methionyl-tryptophan,Methionyl tryptophan
	Methionyl-Tryptophan is a dipeptide composed of methionine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism.
T11897	Telotristat ethyl	LX1606	Hydroxylase
	Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.		Hydroxylase
T14119	ACT-678689	Compound Example 1.53.4	Hydroxylase
	ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].		Hydroxylase
T10142L	P-Ethynylphenylalanine hydrochloride	4-Ethynyl-L-phenylalanine HCL,p-Ethynylphenylalanine hydrochloride(278605-15-5 free base)	Hydroxylase
	p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1]. The potential for p-Ethynylphenylalanine hydrochloride to inhibit selectively and reversibly the b...		Hydroxylase
T3119	JNJ-63533054	JNJ 63533054	GPR
	JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.		GPR
T19889	L-5-BromoTryptophan	5-BrW,5 BrW	Others
	L-5-BromoTryptophan (5-BrW) is an analog of the tryptophan (Trp) effector and inhibits the gelation of hemoglobin S.		Others
T6044	Telotristat Etiprate	LX1606 (Hippurate),LX 1606 Hippurate	Hydroxylase
	Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.		Hydroxylase
T41143	PCPA methyl ester hydrochloride	4-Chloro-DL-phenylalanine methyl ester hydrochloride	5-HT Receptor , Hydroxylase
	pCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride) is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood...		5-HT Receptor , Hydroxylase
T1447	Fenclonine	Fenchlonine,PCPA,CP-10188,4-Chloro-DL-phenylalanine,DL-4-Chlorophenylalanine	Hydroxylase
	Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine(CP-10188) acts pharmacologically to dep...		Hydroxylase
T11449L2	Golotimod (TFA) (229305-39-9 free base)	SCV 07 (TFA),Gamma-D-glutamyl-L-tryptophan (TFA),Golotimod (TFA)	STAT
	Golotimod TFA (SCV 07 TFA) is an immunomodulatory peptide with antibacterial properties that significantly increases the effectiveness of anti-tuberculosis studies, stimulates thymus and splenocyte proliferation and impr...		STAT
T11449	Golotimod hydrochloride (229305-39-9 free base)	Golotimod hydrochloride,Gamma-D-glutamyl-L-tryptophan hydrochloride,SCV 07 hydrochloride	STAT
	Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial properties. It enhances antituberculosis therapy effectiveness, promotes thymic and splenic cell proliferation, and boosts ...		STAT
TP1319	Indolicidin		Antibacterial
	Indolicidin is comprised of 13 amino acids, 5 of which are tryptophan residues, and the carboxylterminal arginine is carboxamidated. Indolicidin has the highest tryptophan content of any known protein.		Antibacterial
T29842	Alclofenac	W 7320,MY 101,BRN 2116510,W-7320,W7320	Others
	Alclofenac (W-7320) has a significant effect on the acute phase protein response and the degree of L-tryptophan binding to plasma protein and can be used in the treatment of patients with chronic rheumatism.		Others
T37683	3-Hydroxykynurenine	3-hydroxy-DL-Kynurenine,DL-3-Hydroxykynurenine	Others
	3-Hydroxykynurenine (3-hydroxy-DL-Kynurenine) is an active metabolite of tryptophan and inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%.		Others
T10142	P-Ethynylphenylalanine	4-Ethynyl-L-phenylalanine	Others , Hydroxylase
	p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of 32.6 μM.		Others , Hydroxylase
T61202	TDO-IN-1		Others
	TDO-IN-1 is an orally active, potent, and selective inhibitor of tryptophan 2,3-dioxygenase (TDO), which inhibits indoleamine-2,3-dioxygenase.TDO-IN-1 has antitumor activity and is able to act by reversing local immune t...		Others
T26258	Telotristat besilate
	Telotristat besilate is an inhibitor of tryptophan hydroxylase.
T19888	6BrW	6-BrW,6 BrW
	6BrW is an analog of tryptophan effector.
T16780	Rodatristat	KAR5417	Others
	Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).		Others
T15426	GSK180		Hydroxylase
	GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism.		Hydroxylase
T34962	Tryptophyl-leucyl-glutamic acid	Trp-leu-glu
	Tryptophyl-leucyl-glutamic acid is a tryptophan used for fluorescence spectroscopy.
T69135	AGN-2979
	AGN-2979 is a tryptophan hydroxylase (TPH) activation inhibitor that shows antidepressant properties in rodent models of depression.
T71888	Fenclonine hydrochloride
	Fenclonine hydrochloride is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.
T15778	LP-533401		Hydroxylase
	LP-533401 is an inhibitor of Tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut.		Hydroxylase
T11623	IDO/TDO-IN-1		Others
	IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM).		Others
T20799	Lobenzarit	Lobenzaritum
	Lobenzarit, an immunomodulator, is most frequently used to treat arthritis. Its chemical scaffold has been repurposed to tryptophan biosynthesis in Mycobacterium tuberculosis
T69944	NLG802 HCl
	NLG802 is an orally bioavailable prodrug of indoximod, a methylated tryptophan, with immune checkpoint inhibitory and antineoplastic activities. Upon oral administration, the indoximod prodrug NLG802 is converted to indo...
T19258	DL-3-Indolylglycine	α-Amino-1H-indole-3-acetic acid,D,L-3-Indolylglycine	Others
	D, L-3-indolylglycine is an unnatural amino acid very similar to tryptophan, and its indole portion is directly connected to the α-position. Target: D, L-3-indolyl glycine can be used for functional protein design. One s...		Others
T76136	Tryptophanase
	Tryptophanase, a bacterial enzyme, catalyzes the degradation of tryptophan into indole, pyruvate, and ammonia [1].
T16779	Rodatristat ethyl	RVT-014,KAR5585,RVT-1201	5-HT Receptor , Hydroxylase
	Rodatristat ethyl (KAR5585) is a first-of-its-kind orally active and potent tryptophan hydroxylase 1 (TPH1) inhibitor that significantly reduces 5-hydroxytryptamine (5-HT) levels and decreases pulmonary arterial hyperten...		5-HT Receptor , Hydroxylase
T36363	Dnp-RPLALWRS (trifluoroacetate salt)
	Dnp-RPLALWRS is a fluorogenic substrate for matrix metalloproteinase-7 (MMP-7). The activity of MMP-7 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-t...
T32161	Indoxyl sulfate
	Indoxyl sulfate is a metabolite of tryptophan, showing adverse effects on bones and the central nervous system, having been most frequently implicated as a contributor to renal disease progression and vascular disease
T38472	Phosphoribosyl pyrophosphate pentasodium	PRPPpentasodium
	Phosphoribosyl pyrophosphate (PRPP) pentasodium is a vital metabolite essential for the biosynthesis of purine and pyrimidine nucleotides, as well as the amino acids histidine and tryptophan. It also acts as a precursor ...
T76575	Arg-Trp
	Arg-Trp, a dipeptide consisting of arginine and tryptophan, and its analogues, specifically the octyl ester, exhibit antibacterial activity [1].
T76626	H-Trp-Trp-Trp-OH
	H-Trp-Trp-Trp-OH is a tripeptide composed of tryptophan residues and exhibits antibacterial activity [1].

Compounds

N-Cbz-DL-tryptophan

T9343

Synonym:

Target: cholecystokinin

6-fluoro-DL-Tryptophan

T7694

Synonym:

Target: 5-HT Receptor

Tryptophan, N-indol-3-ylacetyl- (6CI)

T5489

Synonym: N-(3-Indolylacetyl)-L-tryptophan,Indole-3-acetyl-L-tryptophan

Target: Glucosidase

DL-Tryptophan octyl ester (hydrochloride)

T38112

Synonym:

Target:

o-Nitrophenylsulfenyl-lysyl-tryptophan

Synonym: trans-Caffeoyl-L-tryptophan

Target: Sirtuin

Golotimod

T11449L

Synonym: Gamma-D-glutamyl-L-tryptophan,SCV 07

Target: Antibiotic

RG108

T2038

Synonym: N-Phthalyl-L-tryptophan

Target: DNA Methyltransferase

N-Valyltryptophan

T20540

Synonym: Val-trp,L-Valyl-L-tryptophan

Target: Others

Indoximod

T6543

Synonym: NLG-8189,Indoximod (NLG-8189）,1-Methyl-D-tryptophan

Target: Indoleamine 2,3-Dioxygenase (IDO)

Target: Hydroxylase, LPA Receptor

N-Malonyl DL-tryptophan

Synonym: Met-trp,Methionyl-tryptophan,Methionyl tryptophan

Synonym: Compound Example 1.53.4

Target: Hydroxylase

p-Ethynylphenylalanine hydrochloride

T10142L

Synonym: 4-Ethynyl-L-phenylalanine HCL,p-Ethynylphenylalanine hydrochloride(278605-15-5 free base)

Target: Hydroxylase

JNJ-63533054

T3119

Synonym: JNJ 63533054

Synonym: LX1606 (Hippurate),LX 1606 Hippurate

Target: Hydroxylase

pCPA methyl ester hydrochloride

T41143

Synonym: 4-Chloro-DL-phenylalanine methyl ester hydrochloride

Target: 5-HT Receptor, Hydroxylase

Fenclonine

T1447

Synonym: Fenchlonine,PCPA,CP-10188,4-Chloro-DL-phenylalanine,DL-4-Chlorophenylalanine

Target: Hydroxylase

Golotimod (TFA) (229305-39-9 free base)

T11449L2

Synonym: SCV 07 (TFA),Gamma-D-glutamyl-L-tryptophan (TFA),Golotimod (TFA)

Target: STAT

Golotimod hydrochloride (229305-39-9 free base)

T11449

Synonym: Golotimod hydrochloride,Gamma-D-glutamyl-L-tryptophan hydrochloride,SCV 07 hydrochloride

Target: Antibacterial

Alclofenac

T29842

Synonym: W 7320,MY 101,BRN 2116510,W-7320,W7320

Target: Others

3-Hydroxykynurenine

T37683

Synonym: 3-hydroxy-DL-Kynurenine,DL-3-Hydroxykynurenine

Target: Others

p-Ethynylphenylalanine

T10142

Synonym: 4-Ethynyl-L-phenylalanine

Target: Others, Hydroxylase

Tryptophyl-leucyl-glutamic acid

Fenclonine hydrochloride

Synonym: Lobenzaritum

Synonym: α-Amino-1H-indole-3-acetic acid,D,L-3-Indolylglycine

Synonym: RVT-014,KAR5585,RVT-1201

Target: 5-HT Receptor, Hydroxylase

Dnp-RPLALWRS (trifluoroacetate salt)

Phosphoribosyl pyrophosphate pentasodium

T38472

Synonym: PRPPpentasodium

カタログ番号	製品名	別名	ターゲット
TN2285	DL-Tryptophan	(±)-Tryptophan,Tryptophan	Serotonin Transporter , Endogenous Metabolite
	DL-Tryptophan ((±)-Tryptophan) containing dipeptides are interesting ingredients for functional foods as a natural prevention for hypertension with reduced side effects due to its selective inhibition of the C-domain. Lo...		Serotonin Transporter , Endogenous Metabolite
T0439	L-Tryptophan	(S)-Tryptophan,Tryptophan,L-Tryptophane,Tryptophane	Amino Acids and Derivatives , Endogenous Metabolite
	L-Tryptophan (Tryptophane), an essential amino acid, is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid) and of ...		Amino Acids and Derivatives , Endogenous Metabolite
T5235	5-Methoxy-DL-tryptophan		Others , Endogenous Metabolite
	5-Methoxy-DL-tryptophan is a molecule produced by endothelial cells to modulate inflammatory responses and protect against systemic inflammation.		Others , Endogenous Metabolite
T8789	N-Acetyl-L-tryptophan	N-acetyltryptophan	Endogenous Metabolite , Neurokinin receptor
	N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).		Endogenous Metabolite , Neurokinin receptor
T5S0273	Hypaphorine	Lenticin,Glyyunnanenine,Tryptophan Betaine	Others
	1. Hypaphorine (Lenticin) is an indole-3-acetic acid antagonist which specifically compete with indole-3-acetic acid in binding to the indole-3-acetic acid-binding site in plant peroxidases.		Others
T4806	H-D-Trp-OH	D-Tryptophan	Others , Endogenous Metabolite
	H-D-Trp-OH (D-Tryptophan) is one of the 20 standard amino acids. The D-stereoisomer is occasionally found in naturally produced peptides (e.g. contryphan, the marine venom peptide).		Others , Endogenous Metabolite
T5718	L-(+)-Abrine	L-N-Methyltryptophan,N-α-Methyl-L-tryptophan,L-ABRINE	Others
	L-(+)-Abrine (L-N-Methyltryptophan) is a toxic protein found in the jequirity seed.,can be used as a biomarker for abrin exposure.		Others
T4833	Ac-DL-Trp-OH	N-Acetyl-DL-tryptophan	Others , Endogenous Metabolite
	Ac-DL-Trp-OH (N-Acetyl-DL-tryptophan) was study for its possible anti- inflammatory and antinociceptive activities from the extraction of a Turkish plant, Salsola grandis.		Others , Endogenous Metabolite
T3S1967	(S)-Indoximod	N-ME-Tryptophan,Abrine,L-Abrine	Others , Indoleamine 2,3-Dioxygenase (IDO)
	(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L...		Others , Indoleamine 2,3-Dioxygenase (IDO)
T7203	Oglufanide	L-Glutamyl-L-tryptophan,H-Glu-Trp-OH	VEGFR , HCV Protease , Endogenous Metabolite
	Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).		VEGFR , HCV Protease , Endogenous Metabolite
T5262	Trans-3-Indoleacrylic acid	trans-IAA	Others , Endogenous Metabolite
	trans-3-Indoleacrylic acid (trans-IAA) is a Tryptophan metabolite.		Others , Endogenous Metabolite
TQ0265	Indolelactic acid		Endogenous Metabolite
	Indolelactic acid is a metabolite of tryptophan in Azotobacter vinelandii cultures.		Endogenous Metabolite
T20585	3-Acetylindole	Acetyl-3-indole,3-Acetyl-1H-indole,3-Acetylindole	Others
	3-Acetylindole (3-Acetyl-1H-indole) can be used as a substituent and a probe to L-tryptophan for Sudlow site II.		Others
T5984	Indole-3-carboxylic acid	3-Indoleformic acid	Endogenous Metabolite
	Indole-3-carboxylic acid (3-Indoleformic acid) is a normal urinary indolic tryptophan metabolite .		Endogenous Metabolite
T7641	5-Hydroxytryptophol		Endogenous Metabolite
	5-Hydroxytryptophol is a metabolite of tryptophan. It is used as a biomarker for recent alcohol consumption and causes sleeping sickness		Endogenous Metabolite
T3003	5-hydroxytryptophan	NSC-92523	Others , Endogenous Metabolite
	5-hydroxytryptophan (NSC-92523) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.		Others , Endogenous Metabolite
T4096	Quinolinic acid	pyridine-2,3-dicarboxylic acid,QUIN	Endogenous Metabolite , NMDAR , iGluR
	Quinolinic acid (QUIN) is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.		Endogenous Metabolite , NMDAR , iGluR
T4921	Oxoadipic acid	2-Oxoadipic acid	Endogenous Metabolite
	Oxoadipic acid (2-Oxoadipic acid) is a key metabolite of the essential amino acids tryptophan and lysine.Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research on mitochondrial metab...		Endogenous Metabolite
T4794	Glutaric acid		Endogenous Metabolite
	Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan		Endogenous Metabolite
T67710	3-Indoleacrylic acid		Endogenous Metabolite
	3-Indoleacrylic acid is a metabolite of tryptophan produced by Peptostreptococcus species. 3-Indoleacrylic acid has a beneficial effect on intestinal epithelial barrier function and mitigates inflammatory responses by im...		Endogenous Metabolite
T3010	Xanthurenic Acid	8-Hydroxykynurenic acid,4,8-Dihydroxyquinaldic acid,xanthurenate	Apoptosis , Endogenous Metabolite , GluR
	Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3).		Apoptosis , Endogenous Metabolite , GluR
TJO2729	L-Alanine	L-2-Aminopropionic acid,alanine	Others , Endogenous Metabolite
	L-Alanine (L-2-Aminopropionic acid) is an Amino Acid. The chemical classification of alanine is Amino Acids. Alanine is a small non-essential amino acid in humans, Alanine is one of the most widely used for protein const...		Others , Endogenous Metabolite
T1379	L-5-Hydroxytryptophan	L-oxitriptan,Oxitriptan,L-5-HTP	Amino Acids and Derivatives , Endogenous Metabolite
	L-5-Hydroxytryptophan (L-5-HTP) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.		Amino Acids and Derivatives , Endogenous Metabolite
T65135	Kynurenic acid	Fibrostop 2,Quinurenic acid	GPR , GluR , NMDAR
	Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and an agonist of GPR35/CXCR8 with neuroprotective and anticonv...		GPR , GluR , NMDAR
T10938	D-Kynurenine	(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103	GPR , AhR , Endogenous Metabolite
			GPR , AhR , Endogenous Metabolite
T4928	L-Kynurenine	(S)-Kynurenine	AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
	L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has ...		AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
T0647	Tryptamine		Dehydrogenase , 5-HT Receptor , Endogenous Metabolite , TRP/TRPV Channel
	Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It is found in trace amounts in the brains of mammals and is r...
T4799	Indole		Others , Endogenous Metabolite
	Indole has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. It can be produced by bacteria as a degradation product of the amino acid tryptophan. ...		Others , Endogenous Metabolite
T4938	Potassium 1H-indol-3-yl sulfate	Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate	AhR , Endogenous Metabolite
	Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR). The Aryl Hydrocarbon Receptor (AhR) has recently emerged as a pathophysiological regulator of imm...		AhR , Endogenous Metabolite
T4707	3-Hydroxyanthranilic acid	3-HYDROXY-2-AMINOBENZOIC ACID	Others , Endogenous Metabolite
	3-Hydroxyanthranilic acid (3-HYDROXY-2-AMINOBENZOIC ACID), also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. 3-Hydroxyanthranilic acid...		Others , Endogenous Metabolite

天然物製品

DL-Tryptophan

TN2285

Synonym: (±)-Tryptophan,Tryptophan

Target: Serotonin Transporter, Endogenous Metabolite

L-Tryptophan

T0439

Synonym: (S)-Tryptophan,Tryptophan,L-Tryptophane,Tryptophane

Target: Amino Acids and Derivatives, Endogenous Metabolite

5-Methoxy-DL-tryptophan

T5235

Synonym:

Target: Others, Endogenous Metabolite

N-Acetyl-L-tryptophan

T8789

Synonym: N-acetyltryptophan

Target: Endogenous Metabolite, Neurokinin receptor

Hypaphorine

T5S0273

Synonym: Lenticin,Glyyunnanenine,Tryptophan Betaine

Target: Others

H-D-Trp-OH

T4806

Synonym: D-Tryptophan

Target: Others, Endogenous Metabolite

L-(+)-Abrine

T5718

Synonym: L-N-Methyltryptophan,N-α-Methyl-L-tryptophan,L-ABRINE

Target: Others

Ac-DL-Trp-OH

T4833

Synonym: N-Acetyl-DL-tryptophan

Target: Others, Endogenous Metabolite

(S)-Indoximod

T3S1967

Synonym: N-ME-Tryptophan,Abrine,L-Abrine

Target: Others, Indoleamine 2,3-Dioxygenase (IDO)

Oglufanide

T7203

Synonym: L-Glutamyl-L-tryptophan,H-Glu-Trp-OH

Target: VEGFR, HCV Protease, Endogenous Metabolite

trans-3-Indoleacrylic acid

T5262

Synonym: trans-IAA

Target: Others, Endogenous Metabolite

Indolelactic acid

TQ0265

Synonym:

Target: Endogenous Metabolite

3-Acetylindole

T20585

Synonym: Acetyl-3-indole,3-Acetyl-1H-indole,3-Acetylindole

Target: Others

Indole-3-carboxylic acid

T5984

Synonym: 3-Indoleformic acid

Target: Endogenous Metabolite

5-Hydroxytryptophol

T7641

Synonym:

Target: Endogenous Metabolite

5-hydroxytryptophan

T3003

Synonym: NSC-92523

Target: Others, Endogenous Metabolite

Quinolinic acid

T4096

Synonym: pyridine-2,3-dicarboxylic acid,QUIN

Target: Endogenous Metabolite, NMDAR, iGluR

Oxoadipic acid

T4921

Synonym: 2-Oxoadipic acid

Target: Endogenous Metabolite

Glutaric acid

T4794

Synonym:

Target: Endogenous Metabolite

3-Indoleacrylic acid

T67710

Synonym:

Target: Endogenous Metabolite

Xanthurenic Acid

T3010

Synonym: 8-Hydroxykynurenic acid,4,8-Dihydroxyquinaldic acid,xanthurenate

Target: Apoptosis, Endogenous Metabolite, GluR

L-Alanine

TJO2729

Synonym: L-2-Aminopropionic acid,alanine

Target: Others, Endogenous Metabolite

L-5-Hydroxytryptophan

T1379

Synonym: L-oxitriptan,Oxitriptan,L-5-HTP

Target: Amino Acids and Derivatives, Endogenous Metabolite

Kynurenic acid

T65135

Synonym: Fibrostop 2,Quinurenic acid

Target: GPR, GluR, NMDAR

D-Kynurenine

T10938

Synonym: (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103

Target: GPR, AhR, Endogenous Metabolite

L-Kynurenine

T4928

Synonym: (S)-Kynurenine

Target: AhR, Aryl Hydrocarbon Receptor, Endogenous Metabolite

Tryptamine

T0647

Synonym:

Target: Dehydrogenase, 5-HT Receptor, Endogenous Metabolite, TRP/TRPV Channel

Indole

T4799

Synonym:

Target: Others, Endogenous Metabolite

Potassium 1H-indol-3-yl sulfate

T4938

Synonym: Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate

Target: AhR, Endogenous Metabolite

3-Hydroxyanthranilic acid

T4707

Synonym: 3-HYDROXY-2-AMINOBENZOIC ACID

Target: Others, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01959	Tryptophan Hydroxylase 1/TPH-1 Protein, Human, Recombinant (His)	Human	E. coli
	Tryptophan 5-hydroxylase 1, also known as Tryptophan 5-monooxygenase 1, Tryptophan hydroxylase 1, TPH1, TPH and TPRH, is an enzyme that belongs to the biopterin-dependent aromatic amino acid hydroxylase family. TPH1 cont...
TMPJ-00820	Trp B Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Trp B Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40-50 KDa and the accession number is P0A879.
TMPJ-00819	Trp A Protein, E. coli, Recombinant	E. coli	E. coli
	Trp A Protein, E. coli, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27 KDa and the accession number is P0A877.
TMPH-02958	Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6...
TMPY-02584	14-3-3 beta Protein, Cynomolgus, Recombinant	Cynomolgus	E. coli
	14-3-3 beta Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27.8 kDa and the accession number is Q4R572-2.
TMPY-02378	14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)	Human	E. coli
	The recently identified 14-3-3 tau, whose corresponding gene name is YWHAQ, is in a hypoxia-treated human trophoblast cell line. YWHAQ may play a role in epigenetic regulation of placental genes in the onset of Preeclamp...
TMPY-02179	14-3-3 epsilon Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	14-3-3 epsilon Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 56.1 kDa and the accession number is P62259.
TMPY-02377	14-3-3 eta/YWHAH Protein, Human, Recombinant (GST)	Human	E. coli
	YWHAH, the gene encoding the 14-3-3eta isoform, is highly expressed in retinal ganglion cells (RGC). YWHAH is a positional and functional candidate gene for both schizophrenia and bipolar disorder (BP). It is located on ...
TMPY-01267	14-3-3 epsilon Protein, Human, Recombinant (GST)	Human	E. coli
	14-3-3 epsilon Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 56 kDa and the accession number is P62258-1.
TMPY-01274	14-3-3 epsilon Protein, Human, Recombinant	Human	E. coli
	14-3-3 epsilon Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 29.4 kDa and the accession number is P62258-1.
TMPY-01273	14-3-3 beta Protein, Human, Recombinant	Human	E. coli
	14-3-3 beta Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 28 kDa and the accession number is P31946-1.
TMPY-01266	14-3-3 beta Protein, Human, Recombinant (GST)	Human	E. coli
	14-3-3 beta Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 54.9 kDa and the accession number is P31946-1.
TMPH-01597	KYAT1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the thre...
TMPH-00726	Ribokinase Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a compone...
TMPY-02803	IDO2 Protein, Human, Recombinant (His)	Human	E. coli
	IDO2 belongs to the indoleamine 2,3-dioxygenase family. Indoleamine 2,3-dioxgyenase (IDO), is a cytosolic haem protein which, together with the hepatic enzyme tryptophan 2,3-dioxygenase, catalyzes the conversion of trypt...
TMPH-02679	QPCT Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue...
TMPH-02680	QPCT Protein, Mouse, Recombinant (His & Myc)	Mouse	HEK293 Cells
	Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue...
TMPH-01596	AADAT Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a vari...
TMPJ-01110	IRF5 Protein, Human, Recombinant (His)	Human	E. coli
	Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it ...
TMPJ-00473	QPRTase Protein, Human, Recombinant (His)	Human	E. coli
	Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves ...
TMPJ-01197	CRELD2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cysteine-Rich with EGF-Like Domain Protein 2 (CRELD2) is a secreted protein that is a member of the CRELD family. Human CRELD2 is synthesized as a 353 amino acid precursor protein with a signal peptide, a highly conserve...
TMPY-03753	WARS Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	WARS, also known as TrpRS, is an aminoacyl-tRNA synthetase that belongs to the class-I aminoacyl-tRNA synthetase family. There are two forms of tryptophanyl-tRNA synthetase: a cytoplasmic form, named WARS, and a mitochon...
TMPJ-00813	QDPR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Dihydropteridine reductase, also known as HDHPR and Quinoid dihydropteridine reductase, QDPR and DHPR, belongs to the short-chain dehydrogenases/reductases (SDR) family. QDPR exists as a homodimer. QDPR is part of the pa...
TMPY-06815	SYAP1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Synapse-associated protein 1 (SYAP1), also known as PRO3113 and BSTA, belongs to the synapse-associated BSD domain family, featuring three α-helices and two conserved tryptophan and phenylalanine residues located at the ...
TMPJ-00602	CPA2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carboxypeptidase A2 (CPA) is a secreted pancreatic procarboxy-peptidase that cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified...
TMPH-01248	ADAR Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...

Tryptophan Hydroxylase 1/TPH-1 Protein, Human, Recombinant (His)

TMPY-01959

Species: Human

Expression System: E. coli

Trp B Protein, E. coli, Recombinant (His)

TMPJ-00820

Species: E. coli

Expression System: E. coli

Trp A Protein, E. coli, Recombinant

TMPJ-00819

Species: E. coli

Expression System: E. coli

Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02958

Species: Mouse

Expression System: E. coli

14-3-3 beta Protein, Cynomolgus, Recombinant

TMPY-02584

Species: Cynomolgus

Expression System: E. coli

14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)

TMPY-02378

Species: Human

Expression System: E. coli

14-3-3 epsilon Protein, Mouse, Recombinant (GST)

TMPY-02179

Species: Mouse

Expression System: E. coli

14-3-3 eta/YWHAH Protein, Human, Recombinant (GST)

TMPY-02377

Species: Human

Expression System: E. coli

14-3-3 epsilon Protein, Human, Recombinant (GST)

TMPY-01267

Species: Human

Expression System: E. coli

14-3-3 epsilon Protein, Human, Recombinant

TMPY-01274

Species: Human

Expression System: E. coli

14-3-3 beta Protein, Human, Recombinant

TMPY-01273

Species: Human

Expression System: E. coli

14-3-3 beta Protein, Human, Recombinant (GST)

TMPY-01266

Species: Human

Expression System: E. coli

KYAT1 Protein, Human, Recombinant (His & SUMO)

TMPH-01597

Species: Human

Expression System: E. coli

Ribokinase Protein, E. coli, Recombinant (His)

TMPH-00726

Species: E. coli

Expression System: E. coli

IDO2 Protein, Human, Recombinant (His)

TMPY-02803

Species: Human

Expression System: E. coli

QPCT Protein, Mouse, Recombinant (His)

TMPH-02679

Species: Mouse

Expression System: P. pastoris (Yeast)

QPCT Protein, Mouse, Recombinant (His & Myc)

TMPH-02680

Species: Mouse

Expression System: HEK293 Cells

AADAT Protein, Human, Recombinant (His & SUMO)

TMPH-01596

Species: Human

Expression System: E. coli

IRF5 Protein, Human, Recombinant (His)

TMPJ-01110

Species: Human

Expression System: E. coli

QPRTase Protein, Human, Recombinant (His)

TMPJ-00473

Species: Human

Expression System: E. coli

CRELD2 Protein, Human, Recombinant (His)

TMPJ-01197

Species: Human

Expression System: HEK293 Cells

WARS Protein, Human, Recombinant (His)

TMPY-03753

Species: Human

Expression System: Baculovirus Insect Cells

QDPR Protein, Human, Recombinant (His)

TMPJ-00813

Species: Human

Expression System: HEK293 Cells

SYAP1 Protein, Human, Recombinant (His)

TMPY-06815

Species: Human

Expression System: Baculovirus Insect Cells

CPA2 Protein, Human, Recombinant (His)

TMPJ-00602

Species: Human

Expression System: HEK293 Cells

ADAR Protein, Human, Recombinant (His & SUMO)

TMPH-01248

Species: Human

Expression System: E. coli

カタログ番号	製品名
L2800	Serotonin Receptor-Targeted Compound Library		268 compounds
	A unique collection of 268 compounds targeting serotonin receptors for high throughput screening and high content screening;

ライブラリー

Serotonin Receptor-Targeted Compound Library

L2800

Compounds: 268