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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T7313 | Enclomiphene citrate | Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate | Estrogen Receptor/ERR |
Enclomiphene citrate (trans-Clomiphene citrate) is a non-steroidal estrogen receptor antagonist,with antioestrogenic property | |||
T2398 | Tofacitinib Citrate | CP-690550 citrate,Tasocitinib citrate,Tofacitinib (CP-690550) Citrate | Apoptosis , Influenza Virus , JAK , Antibacterial , Antifungal |
Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM). | |||
T0768 | Oxolamine citrate | AF-438 citrate,SKF-9976 citrate | Others |
Oxolamine citrate (AF-438 citrate) is a cough suppressant that is able to be used as a generic drug in many jurisdictions. | |||
T0464 | Carbetapentane citrate | Pentoxyverine citrate | AChR |
Carbetapentane citrate (Pentoxyverine citrate) , an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold. | |||
T7412 | Tandospirone citrate | SM-3997 citrate | 5-HT Receptor |
Tandospirone citrate (SM-3997 citrate) is a potent and selective 5-HT1A receptor partial agonist (Ki : 27 nM) | |||
T6597 | Mosapride Citrate | TAK-370 citrate,AS-4370 citrate,AS-4370 | 5-HT Receptor |
Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist. | |||
T0467 | Sildenafil citrate | UK-92480 citrate | Apoptosis , PDE , Autophagy |
Sildenafil citrate (UK-92480 citrate) , a cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) Inhibitor, is used extensively for erectile dysfunction and less commonly for pulmonary hypertensio... | |||
T1193 | Clomiphene citrate | NSC 35770,Clomifene citrate | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Clomiphene citrate (NSC 35770) is a selective estrogen receptor modulator. | |||
T9579L | GLP-1 receptor agonist 9 citrate | GLP-1 receptor agonist 9 citrate (2401892-71-3 Free base) | Glucagon Receptor |
GLP-1 receptor agonist 9 citrate is an agonist of GLP-1. | |||
T0056 | Oxeladin citrate | Others | |
Oxeladin citrate is a highly potent and effective cough suppressant, which can treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is no risk of add... | |||
T12017 | Methyllycaconitine citrate | MLA | AChR |
Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier. | |||
T16539 | Piperazine citrate | GABA Receptor | |
Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmintic. | |||
T2016 | MLN9708 | Ixazomib Citrate | Proteasome |
MLN2238 suppresses the chymotrypsin-like proteolytic (β5) site of the 20S proteasome(Ki50=0.93 nM, IC50=3.4 nM/). The biologically active form of MLN9708 (Ixazomib Citrate) is MLN2238 in aqueous solutions or plasma. | |||
T1420 | Diethylcarbamazine citrate | Caritrol,Loxuran,Dicarocide | Lipoxygenase , COX , Parasite |
Diethylcarbamazine citrate (Caritrol) is an anthelmintic used primarily as the citrate in the treatment of filariasis, particular infestations with Wucheria bancrofti or Loa loa. It is an inhibitor of arachidonic acid me... | |||
T8397 | Ixazomib citrate | MLN9708 | Proteasome , Autophagy |
Ixazomib citrate (MLN9708) is a prodrug of Ixazomib (MMLN-2238). MLN9708 is an orally bioavailable second generation proteasome inhibitor (IC50 of 3.4 nM ) with potential antineoplastic activity. | |||
T0428 | Alverine citrate | NSC 35459 | 5-HT Receptor |
Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders. | |||
T6618 | Orphenadrine Citrate | Flexon,Flexoject,Banflex | AChR , iGluR |
Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects. | |||
T64923 | Sodium citrate | Citrosodine,Natrocitral | Others |
Sodium citrate (Natrocitral) is the sodium salt of citric acid.Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Sodium citrate cause oxidative damage of the liver by means of the d... | |||
T40468 | Arimoclomol citrate | Arimoclomol citrate,BRX-220 citrate | |
Arimoclomol citrate (BRX-220 citrate) is a heat shock protein (HSP) co-inducer that acts by enhancing Hsp expression and directly impacting protein aggregation, clearance of misfolded assemblies, and the proteasome-ubiqu... | |||
T38422 | Nelonicline citrate | ABT-126 citrate | |
Nelonicline citrate (ABT-126) is an orally active and selective α7 nicotinic receptor agonist, demonstrating a high affinity for α7 nAChRs in the human brain (Ki = 12.3 nM). This compound is utilized in the research of s... | |||
T33688 | Nitromifene Citrate | Parke davis CI-628,CI-628 citrate,CI 628 citrate,CI628 citrate | |
Nitromifene Citrate is a nonsteroidal estrogen antagonist most commonly used as a research tool in animal studies. | |||
T1120L2 | Dacarbazine citrate | DTIC citrate | |
Dacarbazine citrate is an alkylating agent used to treat cancers of the lymphatic system and malignant melanoma (a type of skin cancer) in patients with certain conditions: islet cell carcinoma (part of the pancreas) Sof... | |||
T34943 | Triisocetyl citrate | Jeechem TISC,Citmol 316,Triisohexadecyl citrate | |
Triisocetyl citrate is a bioactive chemical. | |||
T26277L | Tilarginine citrate | L-Ng-monomethyl arginine citrate | |
Tilarginine citrate is a competitive nitric oxide synthetase inhibitor. | |||
T27175 | Dilopetine Citrate | E-6006 Citrate,E-6039,E6039,E 6039 | |
Dilopetine Citrate, a tachykinin receptor modulator and a neurokinin receptor modulator, is used potentially for the treatment of depression. | |||
T27294 | Ethoheptazine Citrate | Wy-401,Wy 401,Aethoheptazin,Zactane citrate,Wy401 | |
Ethoheptazine Citrate, also known as Zactane and WY-401, is a mycolic acid synthesis inhibitor used to treat tuberculosis. | |||
T12436 | PF-543 Citrate | Sphingosine Kinase 1 Inhibitor II Citrate | S1P Receptor |
PF-543 Citrate is an inhibitor of sphingosine-competitive SPHK1(IC50 of 2 nM ). | |||
T35344 | Maropitant citrate | Neurokinin receptor | |
Maropitant citrate is a useful organic compound for research related to life sciences. The catalog number is T35344 and the CAS number is 359875-09-5. | |||
T19280 | Diethyl aminoethyl hexanoate citrate | DA-6 citrate,2-Diethylaminoethyl hexanoate citrate | Others |
Diethyl aminoethyl hexanoate citrate (2-Diethylaminoethyl hexanoate citrate) is a compound that is widely used as a plant growth regulator stimulates the regeneration of adventitious buds. | |||
T71183 | Simpinicline citrate | ||
Simpinicline citrate is a nicotinic acetylcholine receptor (nAChR) agonist. | |||
T26364 | NS-2359 citrate | GSK-372475,GSK 372475 citrate,NS2359,GSK 372475,NS 2359,GSK372475,NS-2359 | |
NS-2359 is a serotonin-norepinephrine-dopamine reuptake inhibitor. | |||
T69849 | Deptropine citrate | ||
Deptropine citrate is a well-known H1-histamine receptor antagonist and muscarinic receptor antagonist. It is prescribed frequently for treatment of asthma. Recently deptropine has garnered interest as a potential treatm... | |||
T69696 | TAS-108 citrate | ||
TAS-108, also known as SR16234, is a synthetic, antiestrogenic steroidal compound with potential antitumor activity. TAS-108 binds to and inhibits estrogenic receptor alpha (ERa), mainly expressed in the mammary gland an... | |||
T70029 | Ibrexafungerp citrate | ||
Ibrexafungerp citrate is a triterpenoid antifungal. Similarly to echinocandins, it inhibits the synthesis of 1,3-β-d-glucan. However, it binds to a different site on the enzyme than echinocandins, resulting in limited cr... | |||
T68427 | MLN-3897 citrate | ||
MLN-3897 citrate is a C-C Motif Chemokine Receptor 1 (CCR1) antagonist potentially for the treatment of multiple sclerosis and rheumatoid arthritis. | |||
T34957 | Tristearyl citrate | ||
Tristearyl citrate is a bioactive chemical. | |||
T31617 | Elzasonan citrate | ||
Elzasonan Citrate is a selective 5-HT1B and 5-HT1D receptor antagonist for the treatment of depression. | |||
T25543 | Isoaminile citrate | ||
Isoaminile citrate is a safe and effective central cough suppressant. In animal studies, it was as effective as codeine without any respiratory depression. | |||
T70773 | Noberastine citrate | ||
Noberastine citrate, a histamine H1 antagonist, has potent and specific peripheral antihistaminic activity. Noberastine, a furan derivative of nor-astemizole (an astemizole metabolite), has been shown to have a more rapi... | |||
T22622 | Carbazeran citrate | Others | |
aldehyde oxidase (AO) substrate | |||
T6597L | Mosapride citrate dihydrate | GR-107719-B,Mosapride Citrate,GR 107719 B,AS 4370,AS-4370,TAK-370 | |
Mosapride Citrate is a 5-HT4 receptor agonist used to stimulate gastrointestinal motility via acetylcholine. Mosapride Citrate facilitates acetylcholine release from the enteric cholinergic neurons. | |||
T20885 | Acetyltriethyl citrate | ||
Acetyltriethyl citrate is a biochemical. | |||
T20342 | Acetyltributyl citrate | ||
Acetyltributyl citrate is an agent of plasticizer. | |||
T13415 | Zuclomiphene citrate | Others | |
Zuclomiphene citrate is a cis isomer of Clomiphene citrate, and has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. | |||
T36062 | N-Desmethyl Sildenafil (citrate) | ||
N-Desmethyl sildenafil is a major metabolite of sildenafil . N-Desmethyl sildenafil is formed via oxidative metabolism of sildenafil by the cytochrome (CYP) P450 isoforms CYP3A4, CYP3A5, and CYP3A7. | |||
T71775 | Morantel citrate | ||
Morantel citrate is a potent non-binding site acetylcholine (ACh) receptor agonist that inhibits fumarate reductase. | |||
T31784 | Ferric citrate | JTT 751 | |
Ferric citrate as a source of iron used in cell culture applications can provide iron with a less toxic form compared to free iron salts. | |||
T13898 | SPD-473 citrate | Dopamine Receptor | |
SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake. | |||
T11750 | KDOAM-25 citrate | Others | |
KDOAM-25 citrate is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC 50 s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. Multiple myeloma MM1S cells treate... | |||
T34170 | Proxazole citrate | NSC-303872,NSC 303872,NSC303872 | |
Proxazole citrate is a biochemical. |
カタログ番号 | 製品名 | 別名 | ターゲット |
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TN7238L | Sanguinarine citrate | Sanguinarium citrate,Sanguinarin citrate,Pseudochelerythrine citrate | Antibiotic |
Sanguinarine citrate (Pseudochelerythrine chloride) is an alkaloid derived from Sanguinaria Canadensis with antimicrobial, anti-inflammatory, and analgesic activity that is used in the treatment of oral inflammatory dise... | |||
T20819 | Ammonium iron(III) citrate | Ferric ammonium citrate | Others , Ferroptosis |
Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload leading to cellular iron death and enhances protein production. | |||
T12952 | Sodium citrate dihydrate | Citric acid trisodium salt dihydrate,Trisodium citrate dihydrate | Antibacterial |
Sodium citrate dihydrate (Trisodium citrate dihydrate) is an anticoagulant, and also used as a buffer and food preservatives. | |||
T8069 | Triethyl citrate | Others | |
Triethyl citrate is used in pharmaceutical coatings and plastics. | |||
T0256 | Citric acid trilithium salt tetrahydrate | Lithium citrate tribasic tetrahydrate,Trilithium citrate tetrahydrate | Dehydrogenase , GSK-3 , HIF/HIF Prolyl-Hydroxylase , Antibacterial , GluR |
Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways... | |||
T40244 | Methyl citrate | ||
Methyl citrate, obtained from Opuntia ficus-indica var. saboten Makino fruits, serves as a potent Monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 0.23 mM. | |||
T11589 | Hydroxycitric acid tripotassium hydrate | Potassium citrate monohydrate | ATP Citrate Lyase , HIF/HIF Prolyl-Hydroxylase , HIF |
Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) effectively inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation, and anti-tumor effects. Hydroxycitric acid tr... | |||
TN6870 | TRIMETHYL CITRATE | ||
TRIMETHYL CITRATE is a natural product. | |||
T11590 | (-)-Hydroxycitric acid | Garcinia acid | ATP Citrate Lyase |
(-)-Hydroxycitric acid (Garcinia acid) (Garcinia acid) is the principal acid of fruit rinds of Garcinia cambogia. It is a potent and competitive inhibitor of ATP citrate lyase. (-)-Hydroxycitric acid suppresses fatty aci... | |||
TN7238 | Sanguinarine gluconate | Antioxidant , Antibiotic | |
Sanguinarine gluconate is an alkaloid found in many medicinal plants with antimicrobial antioxidant and antitumor activity. | |||
T12045 | (-)-Hydroxycitric acid lactone | Garcinia lactone | ATP Citrate Lyase |
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, which catalyzes the extramitochondrial cleavage of citrate to oxaloac... | |||
T5544 | 2-Furoic acid | Furan-2-carboxylic acid | Anti-infection , ATP Citrate Lyase , Endogenous Metabolite , Acyltransferase |
2-Furoic acid (Furan-2-carboxylic acid) 2-Furoic acid can reduce serum cholesterol and triglyceride levels and has anti-lipidemic effects. | |||
T4862 | Oxaloacetic acid | Endogenous Metabolite | |
Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate (the ionized form of oxaloacetic acid) ... | |||
T4861 | Trans-Aconitic acid | ATPase , Endogenous Metabolite | |
Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aco... | |||
T79936 | Forrestiacids K | ATP Citrate Lyase | |
Forrestiacid K, a terpenoid derived from Pseudotsuga forrestii, functions as an inhibitor of ATP-citrate lyase (ACL) [1]. | |||
TN1751 | Hydroxycitric acid | ERK , p38 MAPK , Fatty Acid Synthase | |
(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to act as a competitive inhibitor of the enzyme ATP-citrate lyas... | |||
T79935 | Forrestiacids J | ATP Citrate Lyase | |
Forrestiacid J is an inhibitor of ATP-citrate lyase (ACL), exhibiting an IC50 value of 2.6 μM [1]. | |||
T82274 | Gnetuhainin I | ||
Gnetuhainin I (Compound 5), a lignin sourced from Pouzolzia zeylanica, exhibits potent inhibition of ATP citrate lyase (ACLY) with an IC50 value of 2.63 μM [1]. |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-02483 | ATP citrate lyase/ACLY Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP... | |||
TMPY-04070 | Citrate Synthase Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Chondroitin sulphate (CS) glycosaminoglycan chains on cell and extracellular matrix proteoglycans (PGs) can no longer be regarded as merely hydrodynamic space fillers. Overwhelming evidence over recent years indicates th... | |||
TMPH-03412 | Citrate synthase Protein, Rickettsia australis, Recombinant (His & Myc) | Rickettsia australis | E. coli |
Citrate synthase Protein, Rickettsia australis, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 53.6 kDa. Accession number: P51039 | |||
TMPY-02413 | Isocitrate dehydrogenase/IDH1 Protein, Human, Recombinant (His) | Human | E. coli |
Isocitrate dehydrogenase/IDH1 Protein, Human, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 48 kDa. Accession number: O75874 | |||
TMPY-02375 | AcnB Protein, E. coli, Recombinant | E. coli | E. coli |
Escherichia coli contains two major aconitases (Acns), AcnA and AcnB. They are distantly related monomeric Fe-S proteins that contain different arrangements of four structural domains. acnA is specifically subject to Sox... | |||
TMPY-02002 | PHPT1 Protein, Human, Recombinant (His) | Human | E. coli |
PHPT1, also known as 14 kDa phosphohistidine phosphatase, phosphohistidine phosphatase 1, protein janus-A homolog, PHP14, is a cytoplasm protein which belongs to the janus family. PHPT1 / PHP14 is expressed abundantly in... | |||
TMPY-02545 | Aconitase 2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
A homozygous missense mutation was identified in the ACO2 gene (c.1240T>G p.Phe414Val) that segregated with HSP complicated by intellectual disability and microcephaly. Lymphoblastoid cell lines of homozygous carrier pat... | |||
TMPY-02787 | Aconitase 2 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
A homozygous missense mutation was identified in the ACO2 gene (c.1240T>G p.Phe414Val) that segregated with HSP complicated by intellectual disability and microcephaly. Lymphoblastoid cell lines of homozygous carrier pat... |