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T19038 |
NIR-H2O2
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Others
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NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. It responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. |
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T8132 |
Iron sucrose
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Iron saccharate,Sucroferric oxyhydroxide |
Reactive Oxygen Species
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Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia. |
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T13396 |
Zinc Protoporphyrin
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Zinc Protoporphyrin-9,ZnPP,Zn(II)-protoporphyrin IX |
Apoptosis
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Reactive Oxygen Species
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Endogenous Metabolite
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Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-can... |
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T18924 |
Benzenepentacarboxylic Acid
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Pentacarboxybenzene |
Others
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Benzenepentacarboxylic Acid (Pentacarboxybenzene) is a novel fluorescent probe to detect and scavenge HO-. Benzenepentacarboxylic acid is utilized to prove and detect the generation of HO- in H2O2/TAED and H2O2/TBCC alka... |
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T9560 |
MAO-B-IN-2
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MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC 50 values of 0.51 and 7.00 μM, respectively. MAO-B-IN-2 attenuates H2O2-induced cellular damage via good ROS scavenging property. |
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T18972 |
DHBS
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DCHBS |
Others
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DHBS (DCHBS) is used in conjunction with 4-aminoantipyrine (4-AAP) and H2O2 for chromogenic quantitation of peroxidase in coupled enzymatic reactions. |
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T24160 |
IM-54
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IM 54,IM54 |
MLK
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IM-54 is a cell-permeable, effective, and selective necrosis inhibitor. |
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T1282 |
Carteolol hydrochloride
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Arteoptic,Abbott-43326,OPC-1085 hydrochloride,Carteolol HCl,Mikelan |
Adrenergic Receptor
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Carteolol hydrochloride (Abbott-43326) is a synthetic quinolinone derivative, antihypertensive Carteolol Hydrochloride is a nonselective beta-adrenoceptor blocking agent for beta-1 and beta-2 receptors with no membrane-s... |
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T38256 |
Pentafluorobenzenesulfonyl fluorescein
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Others
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Pentafluorobenzenesulfonyl fluorescein itself no fluorescence, but were in the H2O2 in sulfonyl key fluoresce when hydrolyzed. Pentafluorobenzenesulfonyl fluorescein is often treated as selective H2O2 sensors, can be use... |
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T38165 |
FBBBE
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FBBBE is a derivatized fluorescein compound that is used to detect the production hydrogen peroxide (H2O2) by cells. Intracellular H2O2, but not extracellular H2O2, initiates the conversion of FBBBE to fluorescein, resul... |
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T37658 |
MitoP
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MitoP is a phenol product produced by the reaction of H2O2 with the ratiometric mass spectrometry probe MitoB . MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where it... |
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T23135 |
Peroxy Orange 1
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Others
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fluorescent probe for imaging hydrogen peroxide (H2O2) |
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T22982 |
MitoPY1
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Others
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a fluorescent probe for imaging hydrogen peroxide (H2O2) in mitochondria of living cells |
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T13727 |
Huangjiangsu A
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Others
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Huangjiangsu A has hepatoprotective potential against H2O2-induced cytotoxicity and ROS generation and could be promising as potential therapeutic agents for liver diseases. Huangjiangsu A is isolated from D. villosa. |
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T63364 |
Nrf2 activator-5
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Nrf2 activator-5 is a potent activator of Nrf2 that attenuates H2O2-induced oxidative stress and LPS-stimulated inflammation in BV-2 microglia, exhibiting antioxidant and anti-inflammatory activity. |
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T76131 |
Sarcosine oxidase
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Sarcosine oxidase (SAO) catalyzes the oxidative demethylation of sarcosine, producing glycine, H2O2, and 5,10-CH2-tetrahydrofolate, substances commonly utilized in biochemical reactions [1]. |
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T81828 |
MDYYFEER
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MDYYFEER, an antioxidant peptide derived from pancreatin hydrolysate of C-phycocyanin, exhibits strong DPPH and ABTS radical scavenging activities. It has been demonstrated to protect zebrafish larvae against oxidative d... |
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T34472 |
S1QEL
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S-1QEL,S1 QEL,S 1QEL,S1QEL1.1,S1-QEL |
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S1QEL is a suppressor of mitochondrial respiratory complex I site IQ electron leak which suppresses superoxide and/or H2O2 production without altering oxidative phosphorylation. |
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T38071 |
HPF
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The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including neurodegeneration, aging, cancer, and infectious diseases.[1] There are a number of fluorescen... |
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T81799 |
MHLWAAK TFA
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MHLWAAK TFA, an antioxidant peptide derived from the pancreatin hydrolysate of C-phycocyanin, exhibits potent DPPH and ABTS radical scavenging properties. It effectively shields zebrafish larvae against oxidative damage ... |
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T81827 |
MDYYFEER TFA
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MDYYFEER TFA, an antioxidant peptide derived from pancreatin hydrolysate of C-phycocyanin, exhibits potent DPPH and ABTS radical scavenging capability. This compound effectively shields zebrafish larvae against oxidative... |
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T69033 |
Magnesium Oxaloacetate
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Magnesium Oxaloacetate is an inhibitor of the amebicidal activity of activated murine macrophages, helping the parasite to survive within the mouse large intestine and increasing the survival of C. elegans exposed to H2O... |
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T81864 |
MAQAAEYYR
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MAQAAEYYR, an antioxidant peptide derived from the pancreatin hydrolysate of C-phycocyanin, exhibits potent scavenging activities against DPPH and ABTS radicals. It also confers protection to zebrafish larvae against oxi... |
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T68642 |
Kahweol palmitate
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Kahweol palmitate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducin... |
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T37357 |
MXS
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MXS is a mitochondria-targeted fluorescent probe for hypochlorous acid (HOCl).1It selectively fluoresces in the presence of OCl-over O2, H2O2, NO, NO2-, NO3-, O2-, ONOO-, and OH when used at a concentration of 10 μM. MX... |
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T71478 |
Kahweol stearate
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Kahweol stearate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing... |
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T81800 |
MHLWAAK
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MHLWAAK, an antioxidant peptide derived from pancreatin hydrolysate of C-phycocyanin, exhibits potent DPPH and ABTS radical scavenging capabilities. It effectively shields zebrafish larvae against H2O2-induced oxidative ... |
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T71479 |
Kahweol oleate
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Kahweol oleate is emi-syntetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell ... |
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T81863 |
MAQAAEYYR TFA
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MAQAAEYYR TFA, an antioxidant peptide derived from the pancreatin hydrolysate of C-phycocyanin, exhibits potent DPPH and ABTS radical scavenging properties. It confers protection to zebrafish larvae against oxidative dam... |
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T82052 |
IR-990
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IR-990, an activatable NIR-II fluorescent probe featuring an acceptor-π-acceptor (A-π-A) structure, enables real-time in vivo detection of hydrogen peroxide (H2O2). It serves as an effective diagnostic tool for drug-indu... |
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T38099 |
APF
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APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase... |
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T35965 |
MitoTEMPOL
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MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2. Like the related compound MitoTEMPO , MitoTEMPOL combines an antioxidant moiety (here, TEMPOL, also known as 4-h... |
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T68641 |
Kahweol Acetate
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Kahweol Acetate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing ... |
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T71480 |
Kahweol linoleate
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Kahweol linoleate is a semi-syntetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing... |
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T79636 |
PKM2-IN-4
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Compound 5C, referred to as Pkm2-in-4, is a selective PKM2 inhibitor (IC50 = 0.35 µM) that modulates pyruvate-dependent respiration and promotes mitochondrial H2O2 production rate and electron transport system coupling [... |
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T63873 |
Anti-Aβ agent 1A
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Anti-Aβ agent 1A is a potent anti-amyloid-β agent. Anti-Aβ agent 1A significantly inhibits LPS-induced IL-1β, IL-6 and TNF-α levels and reduces H2O2-induced apoptosis in SH-SY5Y cells using the mitochondrial pathway, exh... |
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T61312 |
Antioxidant agent-3
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Antioxidant agent-3 (Compound 14q), a potent antioxidant, exhibits strong scavenging activity against DPPH radicals and ABTS+ radicals, with IC50 values of 26.58 μM and 30.31 μM, respectively. Additionally, it enhances t... |
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T37720 |
Difluorinated H2S Fluorescent Probe 1
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Difluorinated H2S probe 1 is a fluorescent probe for hydrogen sulfide (H2S).1It selectively fluoresces in the presence of H2S over Zn2+, Fe3+, S2O32-, ClO-, SO32-, H2O2, NO2-, cysteine (Cys), homocysteine (Hcy), and glut... |
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T36459 |
CAY10730
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CAY10730 is a turn-on fluorescent probe for the detection of nitroreductase activity, a marker of hypoxia. In the presence of nitroreductase, CAY10730 is transformed into a highly fluorescent molecule that displays excit... |
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T35976 |
6-Formylpterin
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Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (H2O2), as it oxidizes specific substrates in the presence of water and oxygen. 6-Formylpterin is an oxidized pterin produced by photol... |
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T38370 |
CAY10731
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CAY10731 is a fluorescent probe for hydrogen sulfide (H2S).[1] Upon reaction with H2S, fluorescein (FITC) is released and its fluorescence can be used to detect H2S. FITC displays excitation/emission maxima of 485/535 nm... |
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T62262 |
Neuroinflammatory-IN-2
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Neuroinflammatory-IN-2 (compound 7i) is a potent anti-neuroinflammatory agent, capable of acting on MAO-B (IC50: 10.30 μM). Neuroinflammatory-IN-2 inhibits 96.33% of Aβ1-42 aggregation at 25 μM. Neuroinflammatory-IN-2 ex... |
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T60348 |
N1,N11-Diethylnorspermine
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N1,N11-Diethylnorspermine (DENSPM), a spermine analog, serves as a potent anticancer agent by activating polyamine catabolism, which in turn triggers cytochrome c release from mitochondria and activates caspase 3. This p... |
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T36830 |
9-Nitrooleate
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Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate , cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules. LNO2 isomers serve as p... |
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T79251 |
AChE-IN-30
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AChE-IN-30 is an acetylcholinesterase (AChE) inhibitor exhibiting neuroprotective effects with an inhibitory concentration (IC 50) of 4.4 μM. It prevents hydrogen peroxide (H 2 O 2)-induced apoptosis by inhibiting the ac... |
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T36502 |
DCP-Rho1
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DCP-Rho1 |
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DCP-Rho1 is a fluorescent probe for the detection of sulfenic acid-containing proteins.1,2 It displays excitation/emission maxima of 560/581 nm, respectively, and has been used to visualize protein oxidation sites in sit... |
