| TMPY-03419
|
SMAD3 Protein, Human, Mouse, Rat, Recombinant (His & GST)
|
Human,Mouse,Rat |
Baculovirus-Insect Cells |
|
SMAD3 belongs to the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD3 is... |
| TMPY-03291
|
SMAD2 Protein, Mouse, Recombinant (His & GST)
|
Mouse |
Baculovirus-Insect Cells |
|
SMAD2 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD... |
| TMPY-03292
|
SMAD5 Protein, Mouse, Recombinant (His & GST)
|
Mouse |
Baculovirus-Insect Cells |
|
SMAD5 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD... |
| TMPJ-00271
|
SMAD3 Protein, Human, Recombinant (His & Flag)
|
Human |
E. coli |
|
Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by transforming growth factor and in so... |
| TMPY-03469
|
SMAD5 Protein, Mouse, Recombinant
|
Mouse |
Baculovirus-Insect Cells |
|
SMAD5 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD... |
| TMPJ-01108
|
SMAD4 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
SMAD Family Member 4 (SMAD4) is a cytoplasmic protein that belongs to the Dwarfin/SMAD family. SMAD4 contains one MH1 (MAD homology 1) domain and one MH2 (MAD homology 2) domain. It is the component of the heterotrimeric... |
| TMPJ-01129
|
SMAD1 Protein, Human, Recombinant (GST)
|
Human |
E. coli |
|
SMAD Family Member 1 (SMAD1) is a member of the dwarfin/SMAD family. SMAD1 has the highest expression in the heart and skeletal muscle, containing one MAD homology 1 domain and one MAD homology 2 domain, As a transcripti... |
| TMPH-01699
|
SMAD2 Protein, Human, Recombinant (His & SUMO)
|
Human |
E. coli |
|
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in t... |
| TMPH-01701
|
SMAD6 Protein, Human, Recombinant (His & Myc)
|
Human |
Baculovirus |
|
Transforming growth factor-beta superfamily receptors signaling occurs through the Smad family of intracellular mediators. SMAD6 is an inhibitory Smad (i-Smad) that negatively regulates signaling downstream of type I tra... |
| TMPH-01702
|
SMAD6 Protein, Human, Recombinant (E. coli, His & Myc)
|
Human |
E. coli |
|
Transforming growth factor-beta superfamily receptors signaling occurs through the Smad family of intracellular mediators. SMAD6 is an inhibitory Smad (i-Smad) that negatively regulates signaling downstream of type I tra... |
| TMPH-01700
|
SMAD3 Protein, Human, Recombinant (His)
|
Human |
Baculovirus |
|
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in t... |
| TMPY-01059
|
BMPR2 Protein, Human, Recombinant (His)
|
Human |
HEK293 |
|
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin... |
| TMPY-00413
|
TGF beta 2 Protein, Mouse, Recombinant (His)
|
Mouse |
HEK293 |
|
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a... |
| TMPH-01015
|
BMP-3 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of ce... |
| TMPH-01349
|
FOXL2 Protein, Human, Recombinant (His & Myc)
|
Human |
E. coli |
|
Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis th... |
| TMPY-04366
|
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST)
|
Human |
Baculovirus-Insect Cells |
|
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si... |
| TMPY-05771
|
ALK-5 Protein, Human, Recombinant (hFc)
|
Human |
HEK293 |
|
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si... |
| TMPJ-00325
|
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
|
Human |
Human Cells |
|
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A i... |
| TMPY-00683
|
BMPR2 Protein, Human, Recombinant (His & hFc)
|
Human |
HEK293 |
|
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin... |
| TMPJ-00256
|
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human |
Human Cells |
|
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are... |
| TMPJ-00255
|
TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated
|
Human |
Human Cells |
|
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are... |
| TMPJ-00772
|
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
|
Mouse |
Human Cells |
|
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are... |
| TMPY-01358
|
ALK-5 Protein, Human, Recombinant (His & hFc)
|
Human |
HEK293 |
|
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si... |
| TMPY-04203
|
RAB1B Protein, Human, Recombinant (hFc)
|
Human |
HEK293 |
|
RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells. Moreover, down-regulation of RAB1B was also found to promote the proliferation and migration of TNBC ... |
| TMPJ-00622
|
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus |
Human Cells |
|
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are... |
| TMPY-02444
|
ATF2 Protein, Human, Recombinant (His & GST)
|
Human |
Baculovirus-Insect Cells |
|
Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-ac... |
| TMPY-00486
|
ALK-7 Protein, Human, Recombinant (hFc)
|
Human |
HEK293 |
|
ALK-7, also known as ALK7 and ACVR1C, belongs to the ALK family. It is a type I receptor for the TGFB family of signaling molecules. TGF-β is the prototype of a protein superfamily which, in humans, contains at least 35 ... |
| TMPY-04577
|
TGF beta 2 Protein, Rhesus, Recombinant (His)
|
Rhesus |
HEK293 |
|
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a... |
| TMPY-03187
|
ALK-7 Protein, Rhesus, Recombinant (hFc)
|
Rhesus |
HEK293 |
|
ALK-7, also known as ALK7 and ACVR1C, belongs to the ALK family. It is a type I receptor for the TGFB family of signaling molecules. TGF-β is the prototype of a protein superfamily which, in humans, contains at least 35 ... |
| TMPY-00499
|
TMP21 Protein, Human, Recombinant (mFc)
|
Human |
HEK293 |
|
TMED10 disrupts the complex formation between TGF-beta type I (also termed ALK5) and type II receptors (TbetaRII). Misexpression studies revealed that TMED10 attenuated TGF-beta-mediated signaling. A 20-amino acid-long r... |
| TMPY-05314
|
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated
|
Mouse |
HEK293 |
|
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a... |
| TMPJ-01158
|
ALK-2/ACVR1 Protein, Human, Recombinant (hFc)
|
Human |
Human Cells |
|
Activin RIA, also known as ALK-2, TSK-7L, SKR1, TSR-I, and ACTR-I, is a glycosylated 65 kDa type I receptor in the TGF-beta serine/threonine kinase receptor family. Binding of TGF-beta superfamily ligands induces formati... |
| TMPY-00231
|
TGF beta 2 Protein, Canine, Recombinant (His)
|
Canine |
HEK293 |
|
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a... |
| TMPJ-00966
|
GDF-5 Protein, Human, Recombinant
|
Human |
E. coli |
|
Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor... |
| TMPJ-01178
|
TGFBR1 Protein, Mouse, Recombinant (hFc)
|
Mouse |
Human Cells |
|
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Pho... |
| TMPY-01654
|
ITCH Protein, Human, Recombinant (aa 526-903)
|
Human |
E. coli |
|
E3 ubiquitin-protein ligase Itchy homolog, also known as Atrophin-1-interacting protein 4, NFE2-associated polypeptide 1, NAPP1, and ITCH, is a cell membrane protein that contains one C2 domain, one HECT (E6AP-type E3 ub... |
| TMPY-02217
|
HSC70 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
HSPA8, also known as HSC70, is a member of the heat shock protein family due to homology with other heat shock proteins. The heat shock protein 70 family is comprised of both heat-inducible and constitutively expressed m... |
| TMPY-04468
|
STK16 Protein, Human, Recombinant (His & NusA)
|
Human |
E. coli |
|
Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is... |
| TMPY-00681
|
BMP-5 Protein, Human, Recombinant (hFc)
|
Human |
HEK293 |
|
Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily.... |
