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Search Results for " coenzyme "

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102

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T37958	Acetyl Coenzyme A trisodium	Acetyl-CoA trisodium	OXPHOS , Endogenous Metabolite , Autophagy
	Acetyl Coenzyme A trisodium (Acetyl-CoA trisodium) is an important compound in glucose metabolism and lipid metabolism and is involved in the tricarboxylic acid cycle.		OXPHOS , Endogenous Metabolite , Autophagy
T32768	Linoleoyl-coenzyme A	Coenzyme A,linoleoyl-
	Linoleoyl-coenzyme A is a substrate used to investigate the specificity and kinetics of acyl-CoA.
T30997	Coenzyme Q12	Ubiquinone Q-12,Ubiquinone 12,trans-Coenzyme Q12,Coenzyme Q-12,J93.222A
	Coenzyme Q10 is a vitamin-like substance found throughout the body, especially in the heart, liver, kidneys, and pancreas.
T36114	Coenzyme Q2
	Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. In its reduced form, it acts as an antioxidant. Coenzyme Q2 is a precurs...
T37978	Coenzyme FO
	Coenzyme FO, a deazaflavin chromophore, plays a crucial role as a hydride acceptor/donor in the central methanogenic pathway [1][2].
T32598	Lauroyl-coenzyme A	Dodecanoyl-coa,Coenzyme A, lauroyl-,Lauroyl-coa
	Lauroyl-coenzyme A can function as an acyl group carrier, acetyl-CoA. It can be used as an intermediate in lipid metabolism and is involved in lipid biosynthesis and fatty acid transport.
T38025	Cyclohexanoyl Coenzyme A
	Cyclohexanoyl coenzyme A (CHCoA) is an acyl CoA that contains a cyclohexane group. It is the activated form of cyclohexane carboxylic acid (CHC) in R. palustris. CHC is converted to CHCoA by a succinyl-CoA CHC CoA transf...
T37323	Succinyl-Coenzyme A sodium salt	Succinyl-CoA sodium salt,Succinyl-Coenzyme A (sodium salt),Succinyl-CoA	Endogenous Metabolite
	Succinyl-Coenzyme A sodium salt(Succinyl-CoA sodium salt) participates in the citric acid cycle, where it is converted to succinic acid.Succinyl-Coenzyme A (sodium salt) is involved in a variety of metabolic reactions in...		Endogenous Metabolite
T35691	Myristoyl Coenzyme A (hydrate)
	Myristoyl coenzyme A (myristoyl-CoA) is a derivative of CoA that contains the long-chain fatty acid myristic acid . It is a substrate for N-myristoyltransferase during myristoylation, a process that adds a myristoyl grou...
T38473	Malonyl Coenzyme A lithium
	Malonyl Coenzyme A (lithium) is a coenzyme A derivative that is utilized in fatty acid and polyketide synthesis and in the transport of α-ketoglutarate across the mitochondrial membrane. Malonyl Coenzyme A (lithium) is f...
T127402	Coenzyme Q0	CoQ0
	Coenzyme Q0 (CoQ0), a potent, orally active ubiquinone compound derived from Antrodia cinnamomea, induces apoptosis and autophagy. It suppresses HER-2/AKT/mTOR signaling, enhancing apoptosis and autophagy mechanisms. Add...
T37405	Octanoyl Coenzyme A (sodium salt)
	Octanoyl coenzyme A (octanoyl-CoA) is a medium-chain acyl CoA and a metabolic intermediate in mitochondrial fatty acid β-oxidation. Levels of octanoyl-CoA are increased in the liver of patients with Reye's syndrome and β...
T36842	Isobutyryl Coenzyme A (sodium salt)
	Isobutyryl coenzyme A (isobutyryl-CoA) is a short-chain branched acyl CoA. Isobutyryl-CoA is a substrate for isobutyryl-CoA dehydrogenase (IBDH) in the catabolism of valine and an intermediate in the synthesis of isobuty...
T37116	Ethylmalonyl Coenzyme A (sodium salt)
	Ethylmalonyl coenzyme A (CoA) is a key intermediate in the ethylmalonyl-CoA pathway for carbon metabolism in certain bacteria, such asM. extorquens, which uses this pathway when grown on ethylamine.1,2It is produced from...
T37249	Methylmalonyl-Coenzyme A (sodium salt)
	Methylmalonyl coenzyme A (methylmalonyl-CoA) is an intermediate in multiple metabolic pathways in bacteria and eukaryotes.1,2,3It is an intermediate in carbon assimilation in certain bacteria and carbon fixation in plant...
T37755	Phenylacetyl-Coenzyme A (sodium salt)
	Phenylacetyl-coenzyme A (CoA) is a key intermediate in aerobic catabolism of phenylacetate in bacteria such asPseudomonas, when cultured in minimal media using phenylacetate as the sole carbon source.1It is a precursor i...
T78511	Oleoyl coenzyme A lithium	Oleoyl-CoA lithium
	Oleoyl coenzyme A (Oleoyl-CoA) lithium, a thioester derived from oleic acid and coenzyme A, functions as a metabolite in both Escherichia coli and mice [1] [2].
T36827	Acetoacetyl Coenzyme A (sodium salt hydrate)	Acetoacetyl-CoA
	Acetoacetyl-coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway.[1],[2] It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2)...
T74115	Decanoyl coenzyme A
	Decanoyl coenzyme A (Decanoyl CoA) serves as a primer for the fatty acid elongation system in Mycobacterium smegmatis [1].
T73805	Acetyl coenzyme A
	Acetyl-coenzyme A (Acetyl-CoA), a membrane-impermeant central metabolic intermediate, plays a crucial role in the TCA cycle and oxidative phosphorylation metabolism. It also serves as the sole donor of acetyl groups for ...
T64276	Octanoyl coenzyme A lithium
	Octanoyl coenzyme A lithium is a derivative of the fatty acid acyl coenzyme A. Octanoyl coenzyme A lithium inhibits citrate synthase and glutamate dehydrogenase (IC50: 0.4-1.6 mM).
T74043	Hexanoyl coenzyme A trilithium
	Hexanoyl coenzyme A trilithium, a medium-chain fatty acyl coenzyme A derivative found universally in organisms, serves as a precursor for cannabinoid biosynthesis and functions as a competitive inhibitor of medium-chain ...
T76124	Acyl coenzyme A synthetase
	Acyl coenzyme A synthetase (ACS), also known as acetyl coenzyme A synthetase, plays a pivotal role in biochemical research. This enzyme catalyzes the activation of fatty acids via coenzyme A through a two-step thioesteri...
T73796	Acetyl coenzyme A lithium
	Acetyl-coenzyme A (Acetyl-CoA) lithium, a membrane-impermeant central metabolic intermediate, is integral to the TCA cycle and oxidative phosphorylation. It regulates cellular mechanisms by serving as the sole donor of a...
T74038	Palmitoyl coenzyme A lithium
	Palmitoyl coenzyme A lithium, an acyl-CoA thioester, facilitates transport into the mitochondrial matrix through the carnitine shuttle system for β-oxidation. Additionally, it serves as a substrate in sphingosine biosynt...
T74039	Arachidonoyl coenzyme A lithium
	Arachidonoyl coenzyme A lithium, an unsaturated fatty acyl coenzyme A derivative, results from the condensation of coenzyme A's thiol group with arachidonic acid's carboxyl group [1].
T82293	Glutaryl coenzyme A lithium
	Glutaryl coenzyme A lithium, a derivative of the endogenous metabolite glutaryl coenzyme A, is utilized in experiments related to HMG-CoA or glutaryl-CoA.
T73918	Lauroyl coenzyme A lithium
	Lauroyl coenzyme A lithium salt is a kind of coenzyme A. Coenzyme A acts as an acyl carrier, namely acetyl-CoA. Lauryl-CoA (C12-CoA) is a long-chain (C-12) saturated fatty acyl-CoA that functions as an intermediate in li...
T74172	Acetoacetyl coenzyme A sodium
	Acetoacetyl coenzyme A sodium, a pivotal endogenous metabolite, exhibits a K m of 1.10 mM at pH 7.5 and plays a crucial role in the synthesis of phosphotransbutyrylase (PTB) and poly-3-hydroxybutyrate (PHB) [1] [2].
T74036	β-Methylcrotonyl coenzyme A lithium
	β-Methylcrotonyl coenzyme A lithium, a key intermediate in leucine metabolism, serves as a substrate to investigate the specificity and kinetics of β-methylcrotonyl coenzyme A carboxylase (MCCase) [1].
T74037	DL-β-Hydroxybutyryl coenzyme A lithium
	DL-β-Hydroxybutyryl coenzyme A lithium, an intermediate in butyric acid fermentation and lysine and tryptophan metabolism, is synthesized from β-hydroxybutyric acid by short-chain-CoA synthase [1] [2].
T3510	Olumacostat Glasaretil		Acetyl-CoA Carboxylase
	Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.		Acetyl-CoA Carboxylase
T5046	Haloxyfop	Haloxyfop Acid,(±)-Haloxyfop	Others , Acetyl-CoA Carboxylase
	(±)-Haloxyfop (Haloxyfop Acid) is a herbicide.		Others , Acetyl-CoA Carboxylase
TQ0243	ND-646		Acetyl-CoA Carboxylase
	ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively)		Acetyl-CoA Carboxylase
T7163	PF-05175157		Acetyl-CoA Carboxylase
	PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively		Acetyl-CoA Carboxylase
T0412	Idebenone	CV-2619	Apoptosis , Antioxidant , Mitochondrial Metabolism
	Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).		Apoptosis , Antioxidant , Mitochondrial Metabolism
T3988	TOFA	MDL14514,RMI14514	Acetyl-CoA Carboxylase
	TOFA (MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).		Acetyl-CoA Carboxylase
T14991	CMS-121	CMS121	Acetyl-CoA Carboxylase
	CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotect...		Acetyl-CoA Carboxylase
T1889	CP-640186	CP 640186	Acetyl-CoA Carboxylase
	CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.		Acetyl-CoA Carboxylase
T3622	CP-640186 hydrochloride	CP 640186 HCl	Acetyl-CoA Carboxylase
	CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit...		Acetyl-CoA Carboxylase
T7184	Firsocostat	ND-630,NDI-010976,GS-0976	Acetyl-CoA Carboxylase
	Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)		Acetyl-CoA Carboxylase
T12225L	Nevanimibe hydrochloride	PD-132301 hydrochloride,ATR101 hydrochloride	Apoptosis , Acyltransferase
	Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).		Apoptosis , Acyltransferase
T35659	3'-Dephosphocoenzyme A
	3'-Dephosphocoenzyme A is an intermediate in the biosynthesis of coenzyme A from pantothenic acid .1 It is phosphorylated by CoA synthase in humans to form CoA. 3'-Dephosphocoenzyme A can be used as a transcription initi...
T8754	CPD2028		Others
	CPD2028 is an intermediate of ND630, a potent acetyl coenzyme A carboxylase (ACC) inhibitor.		Others
T30961	CL 277082	CL277082,CL-277082,Ddpmhu	Others
	CL 277082 (Ddpmhu) is an acyl coenzyme A:cholesterol O-acyltransferase inhibitor that inhibits granuloma tissue ACAT activity.		Others
T28009	ME-3221	ME3221
	Apomine is an inhibitor of HMG-CoA-reductase. It promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo. Apomine enhances the antitumor effects of lovastatin on myeloma cells ...
T25276	Crilvastatin	PMD387,PMD 387,PMD-387	HMG-CoA Reductase
	Crilvastatin (PMD 387) is a novel non-competitive hydroxymethylglutaryl coenzyme A reductase inhibitor with cholesterol-lowering activity that inhibits cholesterol uptake in rats with hereditary hypercholesterolemia.		HMG-CoA Reductase
T8314	RP-64477	RP64477	Acyltransferase
	RP-64477 is the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitor.		Acyltransferase
T25651	Lecimibide	DuP128,DuP-128,DuP 128	Acyltransferase
	Lecimibide (DuP 128) is a potent and selective inhibitor of acyl coenzyme A: cholesterol acyltransferase (ACAT), which can be used to study diseases due to high lipids.		Acyltransferase
T6851	NADP sodium salt	Sodium NADP	Others
	NADP sodium salt (Sodium NADP) is a coenzyme that is widely distributed in living matter. Participates in oxidation-reduction reactions.		Others

Compounds

Acetyl Coenzyme A trisodium

T37958

Synonym: Acetyl-CoA trisodium

Target: OXPHOS, Endogenous Metabolite, Autophagy

Linoleoyl-coenzyme A

T32768

Synonym: Coenzyme A,linoleoyl-

Target:

Coenzyme Q12

T30997

Synonym: Ubiquinone Q-12,Ubiquinone 12,trans-Coenzyme Q12,Coenzyme Q-12,J93.222A

Synonym: Dodecanoyl-coa,Coenzyme A, lauroyl-,Lauroyl-coa

Target:

Cyclohexanoyl Coenzyme A

T38025

Synonym:

Target:

Succinyl-Coenzyme A sodium salt

T37323

Synonym: Succinyl-CoA sodium salt,Succinyl-Coenzyme A (sodium salt),Succinyl-CoA

Target: Endogenous Metabolite

Myristoyl Coenzyme A (hydrate)

T35691

Synonym:

Target:

Malonyl Coenzyme A lithium

Octanoyl Coenzyme A (sodium salt)

T37405

Synonym:

Target:

Isobutyryl Coenzyme A (sodium salt)

T36842

Synonym:

Target:

Ethylmalonyl Coenzyme A (sodium salt)

T37116

Synonym:

Target:

Methylmalonyl-Coenzyme A (sodium salt)

T37249

Synonym:

Target:

Phenylacetyl-Coenzyme A (sodium salt)

T37755

Synonym:

Target:

Oleoyl coenzyme A lithium

T78511

Synonym: Oleoyl-CoA lithium

Target:

Acetoacetyl Coenzyme A (sodium salt hydrate)

T36827

Synonym: Acetoacetyl-CoA

Target:

Decanoyl coenzyme A

Octanoyl coenzyme A lithium

T64276

Synonym:

Target:

Hexanoyl coenzyme A trilithium

T74043

Synonym:

Target:

Acyl coenzyme A synthetase

T76124

Synonym:

Target:

Acetyl coenzyme A lithium

T73796

Synonym:

Target:

Palmitoyl coenzyme A lithium

T74038

Synonym:

Target:

Arachidonoyl coenzyme A lithium

T74039

Synonym:

Target:

Glutaryl coenzyme A lithium

T82293

Synonym:

Target:

Lauroyl coenzyme A lithium

T73918

Synonym:

Target:

Acetoacetyl coenzyme A sodium

T74172

Synonym:

Target:

β-Methylcrotonyl coenzyme A lithium

T74036

Synonym:

Target:

DL-β-Hydroxybutyryl coenzyme A lithium

T74037

Synonym:

Target:

Olumacostat Glasaretil

T3510

Synonym:

Target: Acetyl-CoA Carboxylase

Haloxyfop

T5046

Synonym: Haloxyfop Acid,(±)-Haloxyfop

Target: Others, Acetyl-CoA Carboxylase

ND-646

TQ0243

Synonym:

Target: Acetyl-CoA Carboxylase

PF-05175157

T7163

Synonym:

Target: Acetyl-CoA Carboxylase

Idebenone

T0412

Synonym: CV-2619

Target: Apoptosis, Antioxidant, Mitochondrial Metabolism

TOFA

T3988

Synonym: MDL14514,RMI14514

Target: Acetyl-CoA Carboxylase

CMS-121

T14991

Synonym: CMS121

Target: Acetyl-CoA Carboxylase

CP-640186

T1889

Synonym: CP 640186

Target: Acetyl-CoA Carboxylase

CP-640186 hydrochloride

T3622

Synonym: CP 640186 HCl

Target: Acetyl-CoA Carboxylase

Firsocostat

T7184

Synonym: ND-630,NDI-010976,GS-0976

Target: Acetyl-CoA Carboxylase

Nevanimibe hydrochloride

T12225L

Synonym: PD-132301 hydrochloride,ATR101 hydrochloride

Target: Apoptosis, Acyltransferase

3'-Dephosphocoenzyme A

Synonym: CL277082,CL-277082,Ddpmhu

Synonym: PMD387,PMD 387,PMD-387

Target: HMG-CoA Reductase

RP-64477

T8314

Synonym: RP64477

Target: Acyltransferase

Lecimibide

T25651

Synonym: DuP128,DuP-128,DuP 128

Target: Acyltransferase

カタログ番号	製品名	別名	ターゲット
T2796	Coenzyme Q10	Ubiquinone-10,CoQ10	Ferroptosis , Reactive Oxygen Species , Endogenous Metabolite
	Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.
T10857	Coenzyme A		Endogenous Metabolite
	Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.		Endogenous Metabolite
T5573	Coenzyme Q9	Ubiquinone Q9,Ubiquinone 9,CoQ9	Apoptosis , Endogenous Metabolite
	Coenzyme Q9 (Ubiquinone 9) (CoQ9) is a normal constituent of human plasma. CoQ9 in human plasma may originate as a product of incomplete CoQ10 biosynthesis or from the diet.		Apoptosis , Endogenous Metabolite
T14128	Adenosylcobalamin	Cobamamide,Coenzyme B12,AdoCbl	Endogenous Metabolite
	Adenosylcobalamin (AdoCbl) is a biologically active form of vitamin B12 .It is a cofactor for methylmalonyl CoA mutase. It belongs to the corrinoid group of compounds, which contain a corrin macrocycle, and is produced o...		Endogenous Metabolite
T75699	Coenzyme Q6
	Coenzyme Q6 (Ubiquinone 30), an isoprenylated benzoquinone lipid, plays a pivotal role in respiratory electron transport and acts as a lipid antioxidant. Besides, it possesses antioxidant properties that inhibit the gene...
T5283	NADH disodium salt	Disodium NADH,NADH, disodium salt hydrate	Others , Endogenous Metabolite
	NADH disodium salt (Disodium NADH) hydrate is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process, NADH disodium salt hydrate becomes oxid...		Others , Endogenous Metabolite
T8083	Pyridoxal 5'-phosphate monohydrate	Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate	Others
	Pyridoxal 5'-phosphate monohydrate is an active vitamin B6 metabolite		Others
T4761	Pyridoxal hydrochloride		Others , Endogenous Metabolite
	The 4-carboxyaldehyde form of vitamin B6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.		Others , Endogenous Metabolite
T17048	Tetradecanoylcarnitine	L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine	Endogenous Metabolite
	Tetradecanoylcarnitine (L-Myristoylcarnitine) is an acylcarnitine involved in the beta-oxidation of long-chain fatty acids, and is a potential marker for very-long-chain coenzyme A dehydrogenase deficiency. alpha-Dihydro...		Endogenous Metabolite
T4817	Methylmalonic acid	NSC 25201,MMA,Isosuccinic acid,Methylpropanedioic acid,Methylmalonate	Others , Endogenous Metabolite
	Methylmalonic acid (Isosuccinic acid) is a dicarboxylic acid that can be derived from methylmalonyl-coenzyme A. It is an indicator of Vitamin B-12 deficiency in cancer.		Others , Endogenous Metabolite
T0973L	Pyridoxine hydrochloride	Pyridoxine HCl,Pyridoxol (hydrochloride),Vitamin B6 (hydrochloride),Vitamin B6	Nrf2 , Endogenous Metabolite
	Pyridoxine hydrochloride (Vitamin B6) is the 4-methanol form of vitaminB6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingo...		Nrf2 , Endogenous Metabolite
T4874	Thiamine pyrophosphate	Cocarboxylase,Aneurinepyrophosphoric acid,Thiamine pyrophosphate chloride	Endogenous Metabolite
	Thiamine pyrophosphate (Cocarboxylase) is a vitamin B-1 derivative that acts as a coenzyme of transketolase. Thiamine pyrophosphate is used in studies to assess decarboxylation mechanisms in biological systems.		Endogenous Metabolite
T2812	ATP disodium salt hydrate	ATP disodium,ATP disodium salt,Adenosine disodium triphosphate	Others , Endogenous Metabolite
	ATP disodium salt hydrate (Adenosine disodium triphosphate) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.		Others , Endogenous Metabolite
T5067	Flavin adenine dinucleotide disodium salt	Flavin Adenine Dinucleotide Disodium,FAD sodium salt,FAD-Na2	Others , Endogenous Metabolite
	Flavin adenine dinucleotide disodium salt (FAD sodium salt) is a flavin dinucleotide that is synthesized when the AMP moiety from ATP is transferred onto riboflavin 5'-monophosphate. FAD functions as a coenzyme that faci...		Others , Endogenous Metabolite
T1609	NAD+	Cozymase,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD	NADPH , Endogenous Metabolite
	NAD+ (β-Nicotinamide Adenine Dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous...		NADPH , Endogenous Metabolite
T0200	α-Lipoic Acid	Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid	Apoptosis , NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite
	α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme ...
T4766	3-Methylglutaric acid		Endogenous Metabolite
	Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PMID 6181239 ). Methylglutaric acid is als...		Endogenous Metabolite
T64980	ATP disodium trihydrate	Adenosine-5'-triphosphate disodium trihydrate	Endogenous Metabolite
	ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) is an important substance for energy storage and metabolism in the body. It is an important endogenous signaling molecule in immunity and inflammati...		Endogenous Metabolite
T0894	Thiamine hydrochloride	Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride	Apoptosis , HBV , Endogenous Metabolite
	Thiamine hydrochloride (Vitamin B1) is the hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, Thiami...		Apoptosis , HBV , Endogenous Metabolite
T0069	Uracil		Others , Endogenous Metabolite
	Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synt...		Others , Endogenous Metabolite
T1020	Doxorubicin hydrochloride	Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127	Apoptosis , Mitophagy , HBV , HIV Protease , Topoisomerase , Antibacterial , Antibiotic , AMPK , Autophagy
	Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitum...
T1664	Meglutol	Dicrotalic acid,3-Hydroxy-3-methylglutaric acid	Endogenous Metabolite , HMG-CoA Reductase , Autophagy
	Meglutol (3-Hydroxy-3-methylglutaric acid) is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conve...		Endogenous Metabolite , HMG-CoA Reductase , Autophagy
T6480	D-Pantothenic acid	vitamin B5,pantothenate	Others
	D-Pantothenic acid (vitamin B5) is a water-soluble vitamin ubiquitously found in plants and animal tissues with an antioxidant property. D-Pantothenic acid is a component of coenzyme A (CoA) and a part of the vitamin B2 ...		Others
T3578	Pyridoxal phosphate	PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate	Reverse Transcriptase , Endogenous Metabolite
	Pyridoxal phosphate (Vitamin B6 phosphate) is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and d...		Reverse Transcriptase , Endogenous Metabolite
T4867	Erucic acid	Prifac 2990,13(Z)-Docosenoic Acid,cis-13-docosenoic acid	PI3K , Endogenous Metabolite
	Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ). Erucic acid (13(Z)-Docosenoic Acid) is broken down long-chain...		PI3K , Endogenous Metabolite
T2O2721	L-Cysteine	Thioserine,cysteine,L-(+)-Cysteine	Endogenous Metabolite
	L-Cysteine (L-(+)-Cysteine) is a non-essential sulfur-containing amino acid in humans. L-Cysteine is important for protein synthesis, detoxification, and diverse metabolic functions. Found in beta-keratin, the main prote...		Endogenous Metabolite
T1437	D-Panthenol	D-Pantothenyl alcohol,Ilopan,Dexpanthenol,Pantothenol	Endogenous Metabolite
	D-Panthenol (D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent. D-Panthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis...		Endogenous Metabolite
T5287	N-Acetyl-L-aspartic acid	AC-ASP-OH,N-Acetylaspartic acid	Others , Endogenous Metabolite
	N-Acetyl-L-aspartic acid (AC-ASP-OH) is a derivative of aspartic acid. It is the second most concentrated molecule in the brain after the amino acid glutamate. It is synthesized in neurons from the amino acid aspartate a...		Others , Endogenous Metabolite
T19594	Ubiquinone-1		Others
	Ubiquinone-1 is an intermediate for coenzyme Q synthesis.		Others
TN1751	Hydroxycitric acid		ERK , p38 MAPK , Fatty Acid Synthase
	(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to act as a competitive inhibitor of the enzyme ATP-citrate lyas...		ERK , p38 MAPK , Fatty Acid Synthase
T12592	Pyripyropene A		Others
	Pyripyropene A is a potent and selective inhibitor of sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2)(IC50 of 0.07 µM).		Others
T36776	Terpendole C
	Terpendole C is an indole diterpene alkaloid fungal metabolite originally isolated from A. yamanashiensis and an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 2.1 μM in rat liver microsomes). It ...
TN4860	Pueroside B		COX , PPAR
	Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A rece...		COX , PPAR
T36931	Penicillide
	Penicillide is a fungal metabolite originally isolated from Penicillium that has diverse biological activities. It is an inhibitor of calpain 2/m-calpain (IC50 = 7.1 μM) and acyl-coenzyme A:cholesterol acyltransferase (A...
T13199	Triacsin C	WS 1228A,FR 900190	Others
	Triacsin C (WS 1228A) from Streptomyces aureofaciens is a differential inhibitor of arachidonic acid coenzyme A synthetase and non-specific long-chain acyl-coenzyme A synthetase, with anti-atherosclerotic activity, inhib...		Others
T75552	Pomonic acid
	Pomonic acid, a triterpenoid compound, effectively inhibits cholesterol ester accumulation and suppresses acyl coenzyme A:cholesterol acyltransferase (ACAT) activity [1].
T40526	ATP dipotassium	Adenosine5'-triphosphatedipotassium
	ATP dipotassium (Adenosine 5'-triphosphate dipotassium) is a vital compound involved in energy storage and metabolism within living organisms. It plays a crucial role in supplying metabolic energy for driving pumps and a...
T38250	L-Sepiapterin
	L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS). This compound demonstrat...
T36226	Beauveriolide I
	Beauveriolide I is a cyclodepsipeptide that has been found inBeauveriaand an inhibitor of lipid droplet formation.1It inhibits lipid droplet formation when used at concentrations of 3 and 10 μM, as well as inhibits chole...
T83582	(±)-Pantothenic acid	(±)-Vitamin B5,(±)-Pantothenate
	(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is essential for coenzyme A (CoA) biosynthesis in mammalian cells and exhibits protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD...
T36227	Beauveriolide III
	Beauveriolide III is a cyclodepsipeptide that has been found inBeauveriaand an inhibitor of lipid droplet formation.1It inhibits lipid droplet formation when used at concentrations of 3 and 10 μM, as well as inhibits cho...
T37690	Phenylpyropene A
	Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM)....
T36329	Terpendole I
	Terpendole I is a fungal metabolite that has been found in A. yamanashiensis.1 It is a weak inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 145 μM) and is active against the bacteria B. cereus and ...
T5066	Nε,Nε,Nε-Trimethyllysine chloride	Lys(Me)3-OH Chloride,Nε,Nε,Nε-Trimethyllysine hydrochloride	Others , Endogenous Metabolite
	Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of the amino acid lysine. It is a component of histone proteins, a precursor of carnitine and a coenzyme of fatty acid oxidation. Nε,Nε,...		Others , Endogenous Metabolite

天然物製品

Coenzyme Q10

T2796

Synonym: Ubiquinone-10,CoQ10

Target: Ferroptosis, Reactive Oxygen Species, Endogenous Metabolite

Coenzyme A

T10857

Synonym:

Target: Endogenous Metabolite

Coenzyme Q9

T5573

Synonym: Ubiquinone Q9,Ubiquinone 9,CoQ9

Target: Apoptosis, Endogenous Metabolite

Adenosylcobalamin

T14128

Synonym: Cobamamide,Coenzyme B12,AdoCbl

Target: Endogenous Metabolite

Synonym: Disodium NADH,NADH, disodium salt hydrate

Target: Others, Endogenous Metabolite

Pyridoxal 5'-phosphate monohydrate

T8083

Synonym: Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate

Target: Others

Pyridoxal hydrochloride

T4761

Synonym:

Target: Others, Endogenous Metabolite

Tetradecanoylcarnitine

T17048

Synonym: L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine

Target: Endogenous Metabolite

Methylmalonic acid

T4817

Synonym: NSC 25201,MMA,Isosuccinic acid,Methylpropanedioic acid,Methylmalonate

Target: Others, Endogenous Metabolite

Pyridoxine hydrochloride

T0973L

Synonym: Pyridoxine HCl,Pyridoxol (hydrochloride),Vitamin B6 (hydrochloride),Vitamin B6

Target: Nrf2, Endogenous Metabolite

Thiamine pyrophosphate

T4874

Synonym: Cocarboxylase,Aneurinepyrophosphoric acid,Thiamine pyrophosphate chloride

Target: Endogenous Metabolite

ATP disodium salt hydrate

T2812

Synonym: ATP disodium,ATP disodium salt,Adenosine disodium triphosphate

Target: Others, Endogenous Metabolite

Flavin adenine dinucleotide disodium salt

T5067

Synonym: Flavin Adenine Dinucleotide Disodium,FAD sodium salt,FAD-Na2

Target: Others, Endogenous Metabolite

NAD+

T1609

Synonym: Cozymase,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD

Target: NADPH, Endogenous Metabolite

α-Lipoic Acid

T0200

Synonym: Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid

Target: Apoptosis, NF-κB, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite

3-Methylglutaric acid

T4766

Synonym:

Target: Endogenous Metabolite

ATP disodium trihydrate

T64980

Synonym: Adenosine-5'-triphosphate disodium trihydrate

Target: Endogenous Metabolite

Thiamine hydrochloride

T0894

Synonym: Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride

Target: Apoptosis, HBV, Endogenous Metabolite

Uracil

T0069

Synonym:

Target: Others, Endogenous Metabolite

Doxorubicin hydrochloride

T1020

Synonym: Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127

Target: Apoptosis, Mitophagy, HBV, HIV Protease, Topoisomerase, Antibacterial, Antibiotic, AMPK, Autophagy

Meglutol

T1664

Synonym: Dicrotalic acid,3-Hydroxy-3-methylglutaric acid

Target: Endogenous Metabolite, HMG-CoA Reductase, Autophagy

D-Pantothenic acid

T6480

Synonym: vitamin B5,pantothenate

Target: Others

Pyridoxal phosphate

T3578

Synonym: PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate

Target: Reverse Transcriptase, Endogenous Metabolite

Erucic acid

T4867

Synonym: Prifac 2990,13(Z)-Docosenoic Acid,cis-13-docosenoic acid

Target: PI3K, Endogenous Metabolite

L-Cysteine

T2O2721

Synonym: Thioserine,cysteine,L-(+)-Cysteine

Target: Endogenous Metabolite

D-Panthenol

T1437

Synonym: D-Pantothenyl alcohol,Ilopan,Dexpanthenol,Pantothenol

Target: Endogenous Metabolite

N-Acetyl-L-aspartic acid

T5287

Synonym: AC-ASP-OH,N-Acetylaspartic acid

Target: Others, Endogenous Metabolite

Target: ERK, p38 MAPK, Fatty Acid Synthase

Synonym: WS 1228A,FR 900190

Synonym: Adenosine5'-triphosphatedipotassium

Synonym: (±)-Vitamin B5,(±)-Pantothenate

Nε,Nε,Nε-Trimethyllysine chloride

T5066

Synonym: Lys(Me)3-OH Chloride,Nε,Nε,Nε-Trimethyllysine hydrochloride

Target: Others, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01948	COQ7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Ubiquinone biosynthesis protein COQ7 homolog, also known as Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog and COQ7, is a mitochondrion inner membrane and peripheral membrane protein which bel...
TMPH-02825	ACOX1 Protein, Mouse, Recombinant (Myc)	Mouse	E. coli
	Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. First enzyme of the fatty acid beta-oxidation pathway.; Shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing ch...
TMPH-00877	ACSS1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation un...
TMPH-00876	ACSS1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation un...
TMPH-02488	ACSS2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate but can also utilize propionate with a much lower affinity. ACSS2 Protein, Mouse, Recombinant (His) is expressed in E...
TMPY-02481	ACOX1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, ...
TMPJ-00462	NADK Protein, Human, Recombinant (His)	Human	E. coli
	NAD Kinase (NADK) is an enzyme that belongs to the NAD Kinase family. It is a widely expressed enzyme, but it is not detected in skeletal muscle. NADK converts Nicotinamide Adenine Dinucleotide (NAD+) into NADP+, through...
TMPH-01321	FLAD1 Protein, Human, Recombinant (His)	Human	E. coli
	Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. FLAD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predict...
TMPH-02148	SDHA Protein, Human, Recombinant (His)	Human	E. coli
	Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme...
TMPH-00017	AcpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc)	Acholeplasma laidlawii	E. coli
	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc...
TMPY-03507	PPC-DC Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	PPC-DC, also known as PPCDC, belongs to the HFCD (homo oligomeric flavin containing Cys decarboxylase) superfamily which takes a part in the biosynthesis of coenzyme A (CoA) from pantothenate (Vitamin B). Biosynthesis of...
TMPH-00164	4'-phosphopantetheinyl transferase ffp Protein, Bacillus subtilis, Recombinant (His & Myc)	Bacillus subtilis	E. coli
	May activate the peptidyl carrier protein (PCP) domains of fengycin synthase by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. 4'-phosphopantetheinyl transferase ffp Protein, Baci...
TMPH-03596	Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc)	Streptococcus pyogenes	Baculovirus Insect Cells
	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10...
TMPH-03597	Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc)	Streptococcus pyogenes	E. coli
	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system...
TMPH-00590	GlmU Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine...
TMPY-04767	PMVK Protein, Human, Recombinant (His)	Human	E. coli
	PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level a...
TMPH-00425	DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His)	Colwellia psychrerythraea	E. coli
	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential fo...
TMPH-02142	ERR1 Protein, Human, Recombinant (GST)	Human	E. coli
	Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an importan...
TMPH-02150	SUCLG2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the T...
TMPJ-00724	LDHA Protein, Human, Recombinant (His)	Human	E. coli
	L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region,...
TMPY-03406	NMNAT1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	NMNAT, also known as NMNAT1, is a member of the Nicotinamide-nucleotide adenylyltransferases. It is widely expressed with high levels in skeletal muscle, heart, liver, and kidney. NMNAT appears to have the ability to pro...
TMPJ-01265	PPC-DC Protein, Human, Recombinant (aa 1-204, His)	Human	E. coli
	Phosphopantothenoylcysteine Decarboxylase (PPC-DC) is an essential enzyme in the biosynthesis ofCoenzyme A and catalyzes the decarboxylation of PPC to Phosphopantetheine. PPC-DC catalyzes the decarboxylation of the Cyste...
TMPY-01878	L-FABP Protein, Human, Recombinant (His)	Human	E. coli
	Fatty acid-binding protein, liver, also known as Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, FABP1 and FABPL,is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid bindi...
TMPJ-01066	CYCS Protein, Human, Recombinant (His)	Human	E. coli
	Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as...
TMPY-01140	ACOT13/THEM2 Protein, Human, Recombinant (His)	Human	E. coli
	The metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription. Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty ...
TMPY-01345	ACBD6 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Human acyl-coenzyme A binding domain-containing member 6 (ACBD6) is a modular protein that carries an acyl-CoA binding domain at its N terminus and two ankyrin motifs at its C terminus. In mammals, there are six members ...
TMPY-04813	ACAT2 Protein, Rat, Recombinant (His)	Rat	E. coli
	Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two e...