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129

阻害剤

28

天然化合物

64

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2

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カタログ番号 製品名 別名 ターゲット
T36865 Heat Shock Protein Inhibitor II
Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40. Hsp inhibitor II decreases Hs...
T22837 HEAT hydrochloride Others
HEAT hydrochloride is an α1-adrenoceptor antagonist.
T2444 KNK437 Heat Shock Protein Inhibitor I HSP
KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).
T8668 HM03 HSP
HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.
T3594 ML346 HSP
ML346 is a novel activator of Hsp70.
T4125 HSF1A HSP
HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.
T6248 XL888 HSP
XL888 is an ATP-competitive inhibitor of Hsp90 ( IC50: 24 nM). Heat shock protein 90 (Hsp90) is a chaperone that maintains the functionality of client proteins involved in cell proliferation, cell cycling, and apoptosis....
T3652 KRIBB11 Apoptosis , HSP
KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor.
T3487 HSP70-IN-1 Others , HSP
HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).
T8858 DTHIB HSP
DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.
T6558 KW-2478 KW2478 HSP
KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.
T5008 Teprenone Tetraprenylacetone,Geranylgeranylacetone HSP
Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).
T3527 TRC051384 TRC 051384 HSP
TRC051384 is a heat shock protein 70 (HSP70) inducer that reduces stroke-associated neuronal damage and increases survival in a rat model of transient ischemic stroke, activates heat shock factor-1 and leads to elevated ...
T7010 VER-155008 VER155008 GPR , HSP , Autophagy
VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively, >100-fold selectivity over HSP90.
T6855 HA15 Apoptosis , GPR , Others , HSP , Autophagy
HA15 targets specifically BiP/GRP78/HSPA5. HA15 exhibits anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
T5350 JG-98 JG98,JG 98 Apoptosis , HSP
JG-98 is an allosteric Hsp70 inhibitor, displays high active against the breast cancer cell lines MDA-MB-231 and MCF-7 (EC50s: 0.4/0.7 μM).
T16994 Pimitespib TAS-116 HSP
Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).
T10860 Col003 HSP
Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM). It can be used for the investigation of fibrosis.
T2309 Ganetespib STA-9090 Apoptosis , HSP , HIF
Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.
T9202 DDO-5936 HSP
DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.
T3293 Apoptozole Apoptosis Activator VII Apoptosis , HSP
Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.
T6284 Onalespib AT13387,Onalespib (AT13387) HSP
Onalespib (AT13387) is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Onalespib selectively binds to Hsp90, thereby inhibiting its chap...
T0756 Ethoxyquin Santoquin,Quinol,Santoflex HSP , Reactive Oxygen Species
Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.
T7265 HSP27 inhibitor J2 J2 HSP
HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function.
T7261 Grp94 Inhibitor-1 GPR , HSP
Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).
T3454 VER-49009 CCT 129397 HSP
VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).
T8901 YUM70 Apoptosis , GPR , HSP
YUM70 is a potent and selective glucose-regulated protein 78 (GRP78) inhibitor(with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein). It induces endoplasmic reticulum (ER) stress-mediate...
T21551 2-hexyl-4-Pentynoic Acid HDAC
2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.
T2114 VER-82576 NVP-BEP800 HSP
VER-82576 (NVP-BEP800), a synthetic HSP90β inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94.
T8958 PU-H54 GPR
PU-H54 is a purine-based inhibitor of Grp94. It is a Grp94-selective resorcinol-based inhibitor isolated through probing of the exclusive binding region of S2 subpocket in Grp94.
T9804 NPX800 CCT361814 HSP
NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.
T6609 NMS-E973 HSP
NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.
T5152 MKT-077 MKT 077,FJ-776,MKT077 HSP
MKT-077 (FJ-776) is a cationic rhodacyanine dye that demonstrates antiproliferative activity against cancer cell lines (EC50s: 1.4-2.2 μM in vitro) through its ability to inhibit members of the Hsp70 family of molecular ...
T2286 BIIB021 BIIB 021,CNF2024,BIIB-021 HSP , Autophagy
BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).
T7661 SD-169 SD 169 p38 MAPK
SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.
T13554 Arimoclomol maleate BRX-220 HSP
Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.
T6118 NVP-HSP990 HSP990 Apoptosis , HSP
NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).
T6210 Pifithrin-μ PFTμ,NSC 303580,2-Phenylethynesulfonamide HSP , p53 , Autophagy
Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.
T2258 VER-50589 VER50589 Apoptosis , HSP
VER-50589 is a potent HSP90 inhibitor.
T13553 Arimoclomol BRX-220 free base HSP
Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).
T1989 Luminespib AUY922,VER-52296,NVP-AUY922 Apoptosis , HSP , Autophagy
Luminespib (VER-52296) is a new-type inhibitor of HSP90 (IC50s: 7.8/21 nM for HSP90α/β in cell free assay).
T5593 L-Alanyl-L-glutamine Ala-Gln Others , Endogenous Metabolite
L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glutamine (Gln).
T8936 Proteinase K proteinase K for tritirachium album,Protease K Others
Proteinase K (proteinase K for tritirachium album) is a nonspecific serine protease that is useful for general digestion of proteins. It is active in the presence of SDS or urea and over a wide range of pH (4-12), salt c...
T6297 Alvespimycin hydrochloride BMS 826476,NSC 707545,KOS-1022,17-DMAG hydrochloride,Alvespimycin (17-DMAG) HCl Apoptosis , HSP
Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.
T6442 CH5138303 HSP
CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.
T0835 Tamoxifen Citrate Tamoxifen Z-isomer citrate,ICI 46474,ICI 46474 Citrate Apoptosis , Estrogen Receptor/ERR , HSP , Estrogen/progestogen Receptor , Autophagy
Tamoxifen is an antineoplastic nonsteroidal selective estrogen receptor modulator (SERM).
T6804 Chetomin Chaetomin,NSC289491,BRN0077366 Apoptosis , HSP , HIF
Chetomin (BRN0077366) is an inhibitor of HIF-1 by weaken transcription of HIF-1, disrupting the binding of HIF-1α and HIF-2α to p300 at low nanomolar concentrations.
T6906 Tamoxifen ICI 46474,Z-Tamoxifen,trans-Tamoxifen,ICI47699 Apoptosis , Estrogen Receptor/ERR , HSP , Estrogen/progestogen Receptor , Autophagy
Tamoxifen (ICI47699) is a selective and orally effective estrogen receptor modulator (SERM). Tamoxifen has both inhibitory (e.g., mammary cells) and activating (e.g., bone, liver, and uterine cells) activity against estr...
T6379 AMG 517 AMG517,AMG-517 TRP/TRPV Channel
AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1.
T3515 TRC051384 HCl HSP
TRC051384 is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.

Compounds

Heat Shock Protein Inhibitor II
T36865
Synonym:
Target:
HEAT hydrochloride
T22837
Synonym:
Target: Others
KNK437
T2444
Synonym: Heat Shock Protein Inhibitor I
Target: HSP
HM03
T8668
Synonym:
Target: HSP
ML346
T3594
Synonym:
Target: HSP
HSF1A
T4125
Synonym:
Target: HSP
XL888
T6248
Synonym:
Target: HSP
KRIBB11
T3652
Synonym:
Target: Apoptosis, HSP
HSP70-IN-1
T3487
Synonym:
Target: Others, HSP
DTHIB
T8858
Synonym:
Target: HSP
KW-2478
T6558
Synonym: KW2478
Target: HSP
Teprenone
T5008
Synonym: Tetraprenylacetone,Geranylgeranylacetone
Target: HSP
TRC051384
T3527
Synonym: TRC 051384
Target: HSP
VER-155008
T7010
Synonym: VER155008
Target: GPR, HSP, Autophagy
HA15
T6855
Synonym:
Target: Apoptosis, GPR, Others, HSP, Autophagy
JG-98
T5350
Synonym: JG98,JG 98
Target: Apoptosis, HSP
Pimitespib
T16994
Synonym: TAS-116
Target: HSP
Col003
T10860
Synonym:
Target: HSP
Ganetespib
T2309
Synonym: STA-9090
Target: Apoptosis, HSP, HIF
DDO-5936
T9202
Synonym:
Target: HSP
Apoptozole
T3293
Synonym: Apoptosis Activator VII
Target: Apoptosis, HSP
Onalespib
T6284
Synonym: AT13387,Onalespib (AT13387)
Target: HSP
Ethoxyquin
T0756
Synonym: Santoquin,Quinol,Santoflex
Target: HSP, Reactive Oxygen Species
HSP27 inhibitor J2
T7265
Synonym: J2
Target: HSP
Grp94 Inhibitor-1
T7261
Synonym:
Target: GPR, HSP
VER-49009
T3454
Synonym: CCT 129397
Target: HSP
YUM70
T8901
Synonym:
Target: Apoptosis, GPR, HSP
2-hexyl-4-Pentynoic Acid
T21551
Synonym:
Target: HDAC
VER-82576
T2114
Synonym: NVP-BEP800
Target: HSP
PU-H54
T8958
Synonym:
Target: GPR
NPX800
T9804
Synonym: CCT361814
Target: HSP
NMS-E973
T6609
Synonym:
Target: HSP
MKT-077
T5152
Synonym: MKT 077,FJ-776,MKT077
Target: HSP
BIIB021
T2286
Synonym: BIIB 021,CNF2024,BIIB-021
Target: HSP, Autophagy
SD-169
T7661
Synonym: SD 169
Target: p38 MAPK
Arimoclomol maleate
T13554
Synonym: BRX-220
Target: HSP
NVP-HSP990
T6118
Synonym: HSP990
Target: Apoptosis, HSP
Pifithrin-μ
T6210
Synonym: PFTμ,NSC 303580,2-Phenylethynesulfonamide
Target: HSP, p53, Autophagy
VER-50589
T2258
Synonym: VER50589
Target: Apoptosis, HSP
Arimoclomol
T13553
Synonym: BRX-220 free base
Target: HSP
Luminespib
T1989
Synonym: AUY922,VER-52296,NVP-AUY922
Target: Apoptosis, HSP, Autophagy
L-Alanyl-L-glutamine
T5593
Synonym: Ala-Gln
Target: Others, Endogenous Metabolite
Proteinase K
T8936
Synonym: proteinase K for tritirachium album,Protease K
Target: Others
Alvespimycin hydrochloride
T6297
Synonym: BMS 826476,NSC 707545,KOS-1022,17-DMAG hydrochloride,Alvespimycin (17-DMAG) HCl
Target: Apoptosis, HSP
CH5138303
T6442
Synonym:
Target: HSP
Tamoxifen Citrate
T0835
Synonym: Tamoxifen Z-isomer citrate,ICI 46474,ICI 46474 Citrate
Target: Apoptosis, Estrogen Receptor/ERR, HSP, Estrogen/progestogen Receptor, Autophagy
Chetomin
T6804
Synonym: Chaetomin,NSC289491,BRN0077366
Target: Apoptosis, HSP, HIF
Tamoxifen
T6906
Synonym: ICI 46474,Z-Tamoxifen,trans-Tamoxifen,ICI47699
Target: Apoptosis, Estrogen Receptor/ERR, HSP, Estrogen/progestogen Receptor, Autophagy
AMG 517
T6379
Synonym: AMG517,AMG-517
Target: TRP/TRPV Channel
TRC051384 HCl
T3515
Synonym:
Target: HSP
1 2 3
カタログ番号 製品名 別名 ターゲット
TQ0280 Feretoside HSP
Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1).
T8189 Dihydroberberine Potassium Channel , HSP , HER
Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interacti...
T21883 Gedunin HSP
Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Gedunin is an Hsp90 inhibitor, and inhibits ovarian cancer cell proliferation.
T5826 Eupalinolide A HSP
Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.
TN6729 Azadiradione AZD Others
Azadiradione (AZD) (AZD) from the methanolic extract of seeds of Azadirachta indica
T6343 Geldanamycin NSC 122750 HSP , Influenza Virus , Tyrosine Kinases , Antibacterial , Antibiotic
Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.
TJS0928 Calenduloside E Silphioside F Others
Calenduloside E (Silphioside F) exhibits hypoglycemic activities by suppressing the transfer of glucose from the stomach to the small intestine and by inhibiting glucose transport at the brush border of the small intesti...
T2908 Palmitic acid Hexadecoic acid,hexadecanoic acid,Cetylic acid HSP , Endogenous Metabolite
Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms. Palmitic acid has antitumor activity.
T2230 Paeoniflorin Peoniflorin HSP , COX
Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.
TQ0131 Rocaglamide Rocaglamide A,Roc-A HSP , NF-κB , PERK
Rocaglamide (Roc-A), isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells.
T0974 Novobiocin Sodium Albamycinsodium,Cathomycin,Albamycin Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim...
T6290 Tanespimycin 17-AAG,CP 127374,NSC 330507,KOS 953 Apoptosis , Mitophagy , HSP , Antibacterial , Antibiotic , Autophagy
Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).
T7926 Carmoisine Azo Rubine,Chromotrope FB Others
Carmoisine (Azo Rubine) is a food dye Azorubine and is used for the purposes where food is heat-treated after fermentation.
T8017 2-Undecanone Methylnonylketone Others
2-Undecanone (Methylnonylketone) inhibits DnaKJE-ClpB dione-dependent refolding of heat-inactivated bacterial fluorokinase. It has an inhibitory effect on lung tumorigenesis.
T6S2238 Eupalinolide B Others
Eupalinolide A has the effects of relieving phlegm and relieving cough, clearing away heat and detoxification, diuretic swelling and reducing blood pressure.
T5S0229 Isosakuranetin 4'-Methylnaringenin Others
1. Isosakuranetin (4'-Methylnaringenin) has cytotoxic and fungicide properties. 2. Isosakuranetin produces significant decrease in blood pressure. 3. Isosakuranetin significantly reduces the sensitivity of mice to noxiou...
T7177 Capsazepine Apoptosis , TRP/TRPV Channel
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel. It is ...
T1321 Nonivamide Nonanoic acid vanillylamide,Pelargonic acid vanillylamide,Vanillyl-N-nonylamide,Pseudocapsaicin TRP/TRPV Channel
Nonivamide (Nonanoic acid vanillylamide) is found in herbs and spices. Nonivamide is an alkaloid from Capsicum species Nonivamide is a flavoring ingredient. Nonivamide is an organic compound and a capsaicinoid. It is an ...
T2163 Dihydrocapsaicin CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide Others , TRP/TRPV Channel
Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...
TMS1461 Qingyangshengenin B Otophylloside B Beta Amyloid
Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mR...
T4839 Ac-Ala-OH N-Acetylalanine,N-Acetyl-L-alanine Others , Endogenous Metabolite
Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro...
TN3572 Calyxin H HSP
Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it has a possible application as a heat shock protein (HSP) inducer.
T5136 Kongensin A
Kongensin A is an effective heat shock protein 90 (HSP90) inhibitor that has potential anti-necroptosis and anti-inflammation applications.
T10034 (R)-10,11-Dehydrocurvularin 10,11-Dehydrocurvularin Others
10,11-Dehydrocurvularin is an antibiotic and a strong activator of the heat shock response. It inhibits the TGF-β signaling pathway and has anti-tumorous activity.
T75533 Dihydromaniwamycin E
Dihydromaniwamycin E is a heat-shock metabolite exhibiting antiviral activity against influenza and SARS-CoV-2 viruses [1].
TN6613 Delphinidin-3-O-galactoside chloride
Delphinidin-3-O-galactoside chloride has anti-obesity and hypolipidemic effects. Delphinidin-3-O-galactoside (D3G) is a water-soluble anthocyanin with antioxidant activity. D3G is capable of masking the EGCG-induced cyto...
T83319 4-epi-Withaferin A
4-epi-Withaferin A (compound 28), an analogue of Withaferin A, exhibits enhanced cytotoxicity and cytoprotective heat-shock-inducing activity (HSA). It shows promise for the investigation of protein aggregation-associate...
T37219 N-Palmitoyl Glycine
The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolam...

天然物製品

Feretoside
TQ0280
Synonym:
Target: HSP
Dihydroberberine
T8189
Synonym:
Target: Potassium Channel, HSP, HER
Gedunin
T21883
Synonym:
Target: HSP
Eupalinolide A
T5826
Synonym:
Target: HSP
Azadiradione
TN6729
Synonym: AZD
Target: Others
Geldanamycin
T6343
Synonym: NSC 122750
Target: HSP, Influenza Virus, Tyrosine Kinases, Antibacterial, Antibiotic
Calenduloside E
TJS0928
Synonym: Silphioside F
Target: Others
Palmitic acid
T2908
Synonym: Hexadecoic acid,hexadecanoic acid,Cetylic acid
Target: HSP, Endogenous Metabolite
Paeoniflorin
T2230
Synonym: Peoniflorin
Target: HSP, COX
Rocaglamide
TQ0131
Synonym: Rocaglamide A,Roc-A
Target: HSP, NF-κB, PERK
Novobiocin Sodium
T0974
Synonym: Albamycinsodium,Cathomycin,Albamycin
Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy
Tanespimycin
T6290
Synonym: 17-AAG,CP 127374,NSC 330507,KOS 953
Target: Apoptosis, Mitophagy, HSP, Antibacterial, Antibiotic, Autophagy
Carmoisine
T7926
Synonym: Azo Rubine,Chromotrope FB
Target: Others
2-Undecanone
T8017
Synonym: Methylnonylketone
Target: Others
Eupalinolide B
T6S2238
Synonym:
Target: Others
Isosakuranetin
T5S0229
Synonym: 4'-Methylnaringenin
Target: Others
Capsazepine
T7177
Synonym:
Target: Apoptosis, TRP/TRPV Channel
Nonivamide
T1321
Synonym: Nonanoic acid vanillylamide,Pelargonic acid vanillylamide,Vanillyl-N-nonylamide,Pseudocapsaicin
Target: TRP/TRPV Channel
Dihydrocapsaicin
T2163
Synonym: CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide
Target: Others, TRP/TRPV Channel
Qingyangshengenin B
TMS1461
Synonym: Otophylloside B
Target: Beta Amyloid
Ac-Ala-OH
T4839
Synonym: N-Acetylalanine,N-Acetyl-L-alanine
Target: Others, Endogenous Metabolite
Calyxin H
TN3572
Synonym:
Target: HSP
Kongensin A
T5136
Synonym:
Target:
(R)-10,11-Dehydrocurvularin
T10034
Synonym: 10,11-Dehydrocurvularin
Target: Others
Dihydromaniwamycin E
T75533
Synonym:
Target:
Delphinidin-3-O-galactoside chloride
TN6613
Synonym:
Target:
4-epi-Withaferin A
T83319
Synonym:
Target:
N-Palmitoyl Glycine
T37219
Synonym:
Target:

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02443 HSP70 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
HSP70 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 72.2 kDa and the accession number is A8K5I0.
TMPH-00631 Heat-labile enterotoxin B chain Protein, E. coli, Recombinant (His) E. coli E. coli
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
TMPY-01478 HSP90 alpha Protein, Human, Recombinant Human E. coli
HSP90 alpha Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 22.6 kDa and the accession number is K9JA46.
TMPH-00634 Heat-stable enterotoxin ST-2 Protein, E. coli, Recombinant E. coli E. coli
Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells. Heat-stable enterotoxin ST-2 Protein, E. coli, Recombinant is expressed in E. c...
TMPY-06092 HSP70 Protein, Rat, Recombinant (His) Rat HEK293 Cells
HSP70 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.6 kDa and the accession number is A6KTP2.
TMPH-00593 DnaK Protein, E. coli, Recombinant (Yeast, His) E. coli P. pastoris (Yeast)
Acts as a chaperone.
TMPY-02072 HSF1 Protein, Human, Recombinant (His) Human E. coli
Heat shock factor protein 1, also known as heat shock transcription factor 1, HSF1, and HSTF1, is a cytoplasm and nucleus protein that belongs to the HSF family. HSF1 is the major transcription factor of HSPs (heat shock...
TMPH-00632 Heat-labile enterotoxin B chain Protein, E. coli, Recombinant (His & Myc) E. coli E. coli
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. Heat-labile enterotoxin B chain Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression ...
TMPH-00630 Heat-labile enterotoxin A chain Protein, E. coli, Recombinant (His & Myc) E. coli E. coli
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
TMPH-00633 Heat-stable enterotoxin A2 Protein, E. coli, Recombinant (His & Myc & SUMO) E. coli E. coli
Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells.
TMPH-00592 DnaK Protein, E. coli, Recombinant (His) E. coli E. coli
Acts as a chaperone.
TMPY-01924 HSP60 Protein, Mouse, Recombinant (His) Mouse E. coli
HSP60 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 62.3 kDa and the accession number is P63038-1.
TMPJ-01080 HSF2 Protein, Human, Recombinant (His) Human E. coli
Heat Shock Factor Protein 2 (HSF2) belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. In higher eukaryotes, HSF is unable to bind to t...
TMPJ-01411 HSPB11 Protein, Human, Recombinant (His) Human E. coli
Heat Shock Protein β-11 (HSPB11) is a stress-responsive protein that is required to deal with proteotoxic stresses. HSPB11 is composed of an IFT complex B composed of IFT88, IFT57, TRAF3IP1, IFT52, IFT27, HSPB11 and IFT2...
TMPH-00635 Heat-stable enterotoxin ST-IA/ST-P Protein, E. coli, Recombinant (GST) E. coli E. coli
Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells.
TMPH-00071 AtHsp23.6 Protein, Arabidopsis thaliana, Recombinant (His) Arabidopsis thaliana E. coli
AtHsp23.6 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.4 kDa and the accession number is Q96331.
TMPY-04804 Cpn10/HSPE1 Protein, Human, Recombinant (His) Human E. coli
Cpn10/HSPE1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 13.2 kDa and the accession number is A0A384N6A4.
TMPJ-00754 CRYAA Protein, Human, Recombinant (His) Human E. coli
Alpha-Crystallin A Chain (CRYAA) belongs to the small heat shock protein (HSP20) family and can be induced by heat shock. The expression of CRYAA is preferentially restricted to the lens cell. CRYAA may contribute to the...
TMPY-03499 CARHSP1 Protein, Human, Recombinant (His) Human E. coli
CARHSP1 is a biomarker for diabetic complications. Adenovirus-mediated CARHSP1 overexpression and siRNA-mediated knockdown experiments were performed to characterize the role of CARHSP1 in the regulation of gluconeogen...
TMPY-06091 HSP70 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
HSP70 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.5 kDa and the accession number is Q3TU85.
TMPJ-01372 Cornulin Protein, Human, Recombinant (His) Human E. coli
Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-ter...
TMPH-00708 DegP Protein, E. coli, Recombinant (His) E. coli P. pastoris (Yeast)
DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures. Degrades transiently denatured and unfolded or misfolded proteins which accumulate in the periplasm fo...
TMPH-00887 AHSA1 Protein, Human, Recombinant (GST) Human E. coli
Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a re...
TMPJ-00915 HSP40 Protein, Human, Recombinant (His) Human E. coli
DnaJ Homolog Subfamily B Member 1 (DNAJB1) is a member of the heat shock protein family. Heat shock proteins (HSPs) are a highly conserved family of stress response proteins. HSPs function primarily as molecular chaperon...
TMPJ-00755 CRYAB Protein, Human, Recombinant (His) Human E. coli
α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectiv...
TMPJ-01382 HSPB8 Protein, Human, Recombinant (His) Human E. coli
Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in t...
TMPY-01876 HSP60 Protein, Human, Recombinant (His & GST) Human E. coli
HSP60 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 88.7 kDa and the accession number is A0A024R3X4.
TMPY-06846 HSP90 alpha Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
HSP90 alpha Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 87.19 kDa and the accession number is NP_032328.2.
TMPJ-00911 GUCY2C Protein, Human, Recombinant (hFc) Human HEK293 Cells
GUCY2C Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P25092.
TMPJ-01007 HRSP12 Protein, Human, Recombinant (His) Human E. coli
Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA...
TMPJ-00910 GUCY2C Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
GUCY2C Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 65-110 KDa and the accession number is P25092.
TMPJ-01107 PAP Protein, Human, Recombinant (His) Human E. coli
Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents ha...
TMPH-00616 DNA-binding protein H-NS Protein, E. coli, Recombinant (His) E. coli E. coli
A DNA-binding protein implicated in transcriptional repression (silencing). Also involved in bacterial chromosome organization and compaction. H-NS binds tightly to AT-rich dsDNA and inhibits transcription. Binds upstrea...
TMPY-06845 HSP90 alpha Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
HSP90 alpha Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 87.06 kDa and the accession number is NP_005339.3.
TMPY-02217 HSC70 Protein, Human, Recombinant (His) Human E. coli
HSPA8, also known as HSC70, is a member of the heat shock protein family due to homology with other heat shock proteins. The heat shock protein 70 family is comprised of both heat-inducible and constitutively expressed m...
TMPJ-00995 Serpin H1 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is th...
TMPY-06629 TRIA14 Protein, wheat, Recombinant wheat E. coli
TRIA14 Protein, wheat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 kDa.
TMPH-01426 HEATR6 Protein, Human, Recombinant (His & Myc) Human E. coli
HEATR6 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00729 RpoH Protein, E. coli, Recombinant (His & Myc) E. coli E. coli
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. Intrac...
TMPH-01285 EEF1D Protein, Human, Recombinant (His) Human E. coli
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.; Regulates induction of heat-shock-responsive g...
TMPK-00693 HSP27/HSPB1 Protein, Human, Recombinant (His) Human E. coli
Heat shock protein beta-1 (HSPB1, also known as HSP27) is a small heat shock protein involved in many cellular processes and reportedly protects cells against oxidative stress. This protein is expressed only in insulin-d...
TMPH-02298 Urocortin-3 Protein, Human, Recombinant (His & SUMO) Human E. coli
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
TMPK-00016 Cpn10/HSPE1 Protein, Human/Mouse/Goat, Recombinant (His & Avi), Biotinylated Human,Mouse,Goat E. coli
Cpn10/HSPE, a 10-kDa heat shock protein, is a novel interacting partner of NPAT. A pool of Cpn10 is colocalized with NPAT foci during G1 and S phases in nuclei.Cpn10 is important for S phase progression and cell prolifer...
TMPK-00015 Cpn10/HSPE1 Protein, Human/Mouse/Goat, Recombinant (His & Avi) Human,Mouse,Goat E. coli
Cpn10/HSPE, a 10-kDa heat shock protein, is a novel interacting partner of NPAT. A pool of Cpn10 is colocalized with NPAT foci during G1 and S phases in nuclei.Cpn10 is important for S phase progression and cell prolifer...
TMPY-03854 TMED4 Protein, Human, Recombinant (His) Human HEK293 Cells
TMED4, also known as ERS25, belongs to the EMP24/GP25L family. TMED4 may play a role in the regulation of heat-shock response and apoptosis. It is involved in vesicular protein trafficking, mainly in the early secretory ...
TMPY-00342 TMED4 Protein, Human, Recombinant (mFc) Human HEK293 Cells
TMED4, also known as ERS25, belongs to the EMP24/GP25L family. TMED4 may play a role in the regulation of heat-shock response and apoptosis. It is involved in vesicular protein trafficking, mainly in the early secretory ...
TMPH-00094 HSP21, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc) Arabidopsis thaliana E. coli
Chaperone protein required for seedling and chloroplast development under heat stress, probably by maintaining plastid-encoded RNA polymerase (PEP)-dependent transcription. HSP21, chloroplastic Protein, Arabidopsis thali...
TMPH-03310 GUCY2C Protein, Rat, Recombinant (His & Myc) Rat HEK293 Cells
Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin. GUCY2C Protein, Rat...
TMPH-03073 TDX Protein, Japonica rice, Recombinant (His & Myc) Rice E. coli
Probable thiol-disulfide oxidoreductase that may participate in various redox reactions and act as chaperone under heat shock. May interact with HSP70 proteins through the TPR repeats. TDX Protein, Japonica rice, Recombi...
TMPH-00083 Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc) Arabidopsis thaliana E. coli
Intrinsically disordered protein acting as a chaperone. Prevents heat-induced aggregation and/or inactivation of various substrates. Binds to acidic phospholipid vesicles without affecting membrane fluidity. Dehydrin ERD...
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HSP70 Protein, Human, Recombinant (His)
TMPY-02443
Species: Human
Expression System: Baculovirus Insect Cells
Heat-labile enterotoxin B chain Protein, E. coli, Recombinant (His)
TMPH-00631
Species: E. coli
Expression System: E. coli
HSP90 alpha Protein, Human, Recombinant
TMPY-01478
Species: Human
Expression System: E. coli
Heat-stable enterotoxin ST-2 Protein, E. coli, Recombinant
TMPH-00634
Species: E. coli
Expression System: E. coli
HSP70 Protein, Rat, Recombinant (His)
TMPY-06092
Species: Rat
Expression System: HEK293 Cells
DnaK Protein, E. coli, Recombinant (Yeast, His)
TMPH-00593
Species: E. coli
Expression System: P. pastoris (Yeast)
HSF1 Protein, Human, Recombinant (His)
TMPY-02072
Species: Human
Expression System: E. coli
Heat-labile enterotoxin B chain Protein, E. coli, Recombinant (His & Myc)
TMPH-00632
Species: E. coli
Expression System: E. coli
Heat-labile enterotoxin A chain Protein, E. coli, Recombinant (His & Myc)
TMPH-00630
Species: E. coli
Expression System: E. coli
Heat-stable enterotoxin A2 Protein, E. coli, Recombinant (His & Myc & SUMO)
TMPH-00633
Species: E. coli
Expression System: E. coli
DnaK Protein, E. coli, Recombinant (His)
TMPH-00592
Species: E. coli
Expression System: E. coli
HSP60 Protein, Mouse, Recombinant (His)
TMPY-01924
Species: Mouse
Expression System: E. coli
HSF2 Protein, Human, Recombinant (His)
TMPJ-01080
Species: Human
Expression System: E. coli
HSPB11 Protein, Human, Recombinant (His)
TMPJ-01411
Species: Human
Expression System: E. coli
Heat-stable enterotoxin ST-IA/ST-P Protein, E. coli, Recombinant (GST)
TMPH-00635
Species: E. coli
Expression System: E. coli
AtHsp23.6 Protein, Arabidopsis thaliana, Recombinant (His)
TMPH-00071
Species: Arabidopsis thaliana
Expression System: E. coli
Cpn10/HSPE1 Protein, Human, Recombinant (His)
TMPY-04804
Species: Human
Expression System: E. coli
CRYAA Protein, Human, Recombinant (His)
TMPJ-00754
Species: Human
Expression System: E. coli
CARHSP1 Protein, Human, Recombinant (His)
TMPY-03499
Species: Human
Expression System: E. coli
HSP70 Protein, Mouse, Recombinant (His)
TMPY-06091
Species: Mouse
Expression System: HEK293 Cells
Cornulin Protein, Human, Recombinant (His)
TMPJ-01372
Species: Human
Expression System: E. coli
DegP Protein, E. coli, Recombinant (His)
TMPH-00708
Species: E. coli
Expression System: P. pastoris (Yeast)
AHSA1 Protein, Human, Recombinant (GST)
TMPH-00887
Species: Human
Expression System: E. coli
HSP40 Protein, Human, Recombinant (His)
TMPJ-00915
Species: Human
Expression System: E. coli
CRYAB Protein, Human, Recombinant (His)
TMPJ-00755
Species: Human
Expression System: E. coli
HSPB8 Protein, Human, Recombinant (His)
TMPJ-01382
Species: Human
Expression System: E. coli
HSP60 Protein, Human, Recombinant (His & GST)
TMPY-01876
Species: Human
Expression System: E. coli
HSP90 alpha Protein, Mouse, Recombinant (His)
TMPY-06846
Species: Mouse
Expression System: Baculovirus Insect Cells
GUCY2C Protein, Human, Recombinant (hFc)
TMPJ-00911
Species: Human
Expression System: HEK293 Cells
HRSP12 Protein, Human, Recombinant (His)
TMPJ-01007
Species: Human
Expression System: E. coli
GUCY2C Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00910
Species: Human
Expression System: HEK293 Cells
PAP Protein, Human, Recombinant (His)
TMPJ-01107
Species: Human
Expression System: E. coli
DNA-binding protein H-NS Protein, E. coli, Recombinant (His)
TMPH-00616
Species: E. coli
Expression System: E. coli
HSP90 alpha Protein, Human, Recombinant (His)
TMPY-06845
Species: Human
Expression System: Baculovirus Insect Cells
HSC70 Protein, Human, Recombinant (His)
TMPY-02217
Species: Human
Expression System: E. coli
Serpin H1 Protein, Human, Recombinant (His)
TMPJ-00995
Species: Human
Expression System: HEK293 Cells
TRIA14 Protein, wheat, Recombinant
TMPY-06629
Species: wheat
Expression System: E. coli
HEATR6 Protein, Human, Recombinant (His & Myc)
TMPH-01426
Species: Human
Expression System: E. coli
RpoH Protein, E. coli, Recombinant (His & Myc)
TMPH-00729
Species: E. coli
Expression System: E. coli
EEF1D Protein, Human, Recombinant (His)
TMPH-01285
Species: Human
Expression System: E. coli
HSP27/HSPB1 Protein, Human, Recombinant (His)
TMPK-00693
Species: Human
Expression System: E. coli
Urocortin-3 Protein, Human, Recombinant (His & SUMO)
TMPH-02298
Species: Human
Expression System: E. coli
Cpn10/HSPE1 Protein, Human/Mouse/Goat, Recombinant (His & Avi), Biotinylated
TMPK-00016
Species: Human,Mouse,Goat
Expression System: E. coli
Cpn10/HSPE1 Protein, Human/Mouse/Goat, Recombinant (His & Avi)
TMPK-00015
Species: Human,Mouse,Goat
Expression System: E. coli
TMED4 Protein, Human, Recombinant (His)
TMPY-03854
Species: Human
Expression System: HEK293 Cells
TMED4 Protein, Human, Recombinant (mFc)
TMPY-00342
Species: Human
Expression System: HEK293 Cells
HSP21, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc)
TMPH-00094
Species: Arabidopsis thaliana
Expression System: E. coli
GUCY2C Protein, Rat, Recombinant (His & Myc)
TMPH-03310
Species: Rat
Expression System: HEK293 Cells
TDX Protein, Japonica rice, Recombinant (His & Myc)
TMPH-03073
Species: Rice
Expression System: E. coli
Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
TMPH-00083
Species: Arabidopsis thaliana
Expression System: E. coli
カタログ番号 製品名
L6710 Anti-Inflammatory Traditional Chinese Medicine Compound Library

1246 compounds
A collection of 1246 TCM monomers with anti-inflammatory activity or targeting molecular therapeutic targets in inflammation, a powerful tool for drug discovery and mechanism study;
L6740 Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library

382 compounds
A collection of 382 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies.