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Search Results for " neutrophil "

139

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T81316	Rabbit neutrophil peptide 3b
	Rabbit Neutrophil Peptide 3b is an antimicrobial peptide isolated from rabbit peritoneal neutrophils [1].
T79397	Neutrophil elastase inhibitor 4
	Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM. It prompts apoptosis in T47D cells and inhibits the proliferation of T4...
T80323	Bovine neutrophil beta-defensin 12	BNBD-12
	Bovine neutrophil beta-defensin 12, an antimicrobial peptide originating from bovine neutrophils, exhibits antibacterial properties against Escherichia coli and Staphylococcus aureus [1].
T9964	BOS-318		Others
	BOS-318 is a Furin inhibitor with slowly dissociating, highly selective, and cell-pemeable characteristcs.		Others
T8844	Diflapolin		Others , FLAP , Epoxide Hydrolase
	Diflapolin is a highly active dual 5-lipoxygenase-activating protein (FLAP)/soluble epoxide hydrolase (sEH) inhibitor with marked anti-inflammatory efficacy and high target selectivity.		Others , FLAP , Epoxide Hydrolase
T21938	AS-041164		PI3K
	AS-041164 is a selective and orally active PI3Kγ isoform inhibitor(IC50 of 70 nM), and shows less activity against PI3Kα, PI3Kβ, and PI3Kδ (IC50s of 240 nM, 1.45 μM, and 1.70 μM, respectively). It has anti-inflammatory e...		PI3K
T2121	SW033291		Dehydrogenase
	SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.		Dehydrogenase
T13951	UCB-9260		TNF
	UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.		TNF
T11179	Elubrixin	SB-656933	IL Receptor , CXCR
	Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammat...		IL Receptor , CXCR
T16850	SB-265610	GSK-CXCR2	CXCR
	SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and...		CXCR
T39789	BMS-986235	BMS-986235,LAR-1219	Others
	BMS-986235 (LAR-1219) is a selective and orally active agonist of formyl peptide receptor 2 (FPR2) with EC50s of 0.41 nM and 3.4 nM for hFPR2 and mFPR2, respectively. BMS-986235 can be used in studies about the preventio...		Others
T14667	BLT-1		Others , HCV Protease
	BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.		Others , HCV Protease
T9516	Binodenoson	WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos	Adenosine Receptor
	Binodenoson (WRC 0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stres...		Adenosine Receptor
T13389	ZD-0892		PI3K
	ZD-0892 is a selective and poten neutrophil elastaset inhibitor(human neutrophil elastase and porcine pancreatic elastase with Kis of 6.7 and 200 nM, respectively).		PI3K
T3107	Alvelestat	AZD9668,Avelestat	Others , Serine Protease
	Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.		Others , Serine Protease
T6986	Sivelestat	ONO5046,EI546,LY544349	Others , SARS-CoV , Serine Protease
	Sivelestat (ONO5046) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44 nM.		Others , SARS-CoV , Serine Protease
T7130	Navarixin	MK-7123,SCH 527123	CXCR
	Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil trafficking in animal models, characteristics that may be benef...		CXCR
T11828	LDC7559		Pyroptosis
	LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.		Pyroptosis
T12613L	BAY-85-8501		Serine Protease
	BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE; IC50 of 65 pM)		Serine Protease
T8563	2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one		Serine Protease
	2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.		Serine Protease
T35367	Thioacetamide	TAA	Others
	Thioacetamide is a hepatotoxicant used widely to induce experimental liver lesions, develops hepatocellular necrosis and subsequent inflammation (mainly M1-/M2-macrophages without neutrophil infiltration) in rats.		Others
T8602	2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA6-BENZO[D]ISOTHIAZOL-3-ONE		Serine Protease
	2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA6-BENZO[D]ISOTHIAZOL-3-ONE targets the Neutrophil elastase (human).		Serine Protease
T68099	Midesteine	MR-889	Others
	Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.		Others
TP2083L	Ac9-25 acetate	Ac9-25 acetate(284040-76-2 free base)	Others
	Ac9-25 acetate is an annexin AI peptide and activates the neutrophil reduced nicotinamide adenine dinucleotide phosphate oxidase through FPR but not through FPRL1.		Others
T28974	Ticolubant		Calcium Channel , LTR
	Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migration with an IC50 of 6.6 ± 1.5 nM, and shows topical anti-inf...		Calcium Channel , LTR
T10473	BAY-678		Others
			Others
T22277L	BMS-P5 free base		PAD
	BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-...		PAD
T25131	AZD8309	AZD 8309,AZD-8309	Glutathione Peroxidase , CXCR
	AZD8309 is a potent, orally available antagonist of the chemokine receptor CXCR2 that regulates neutrophil transport, significantly reduces MPO in the pancreas and lung, and decreases trypsin and elastase activity in the...		Glutathione Peroxidase , CXCR
TP2334	PMX 53 acetate(219639-75-5 free base)		Complement System
	PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an ag...		Complement System
T20762	Sivelestat sodium tetrahydrate	ONO-5046 sodium tetrahydrate,Elaspol,ONO 5046,ONO5046 sodium tetrahydrate,Elaspol sodium tetrahydrate,ONO-5046,Sivelestat Sodium,Sivelestat Sodium Hydrate,ONO5046	Serine Protease
	Sivelestat sodium tetrahydrate (ONO5046 sodium tetrahydrate) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for...		Serine Protease
T76884	Spesolimab	BI 655130	IL Receptor
	Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. IL-36 plays an important role in the immune system and is associated with a reduction in biomarkers associated with congenital Th1/Th17 and neutrophil p...		IL Receptor
T10831L	Cl-amidine hydrochloride		Apoptosis , PAD
	Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor (IC50: 5.9 μM for PAD4). Cl-amidine hydrochloride induces apoptosis in cancer cells and it also induces microRNA (miR)-16 in vitro ca...		Apoptosis , PAD
T74485	STC314		Others
	STC314 is an anti-infective agent that reverses organ damage caused by excessive immune response by neutralizing extracellular histones and neutrophil trapping networks, and can be used in the study of sepsis and acute r...		Others
T36503	Sodium Hydrogen Sulfide (hydrate)		Others
	Sodium Hydrogen Sulfide (hydrate) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium Hydrogen Sul...		Others
T3107L	Alvelestat tosylate
	Alvelestat can inhibit neutrophil elastase (NE), which acts an important role in NET formation.
T17288	ZD8321		Serine Protease
	ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).		Serine Protease
T15285	FK706		Serine Protease
	FK706 is a slow-binding and competitive human neutrophil elastase inhibitor (IC50: 83 nM; Ki: 4.2 nM). FK706 also inhibits mouse neutrophil elastase and porcine pancreatic elastase (IC50s: 22 nM and 100 nM, respectively)...		Serine Protease
T10254	AE-3763		Serine Protease
	AE-3763 is a peptide-based human neutrophil elastase inhibitor (IC50: 29 nM).		Serine Protease
T31877	Freselestat	ONO-PO 736,ONO-6818,ONO 6818,ONO6818
	Freselestat (ONO-6818) is a potent neutrophil elastase inhibitor that significantly reduces the production of interleukin 8 and C5B-9. Freselestat reduces inflammatory mediators during simulated cardiopulmonary bypass.
T25783	MDL 27399	MDL-27,399,MDL 27,399,MDL27399,MDL27,399
	MDL 27399 suppresses human neutrophil cathepsin G.
T25520	ICI 200355	ICI-200,355,ICI 200,355,ICI-200355,ICI200,355,ICI200355
	ICI 200355 is an inhibitor of human neutrophil elastase.
T25781	MDL 101146	MDL-101146,MD 101,146,MDL101146,MDL 101,146,MDL-101,146
	MDL 101146 is an orally active neutrophil elastase inhibitor.
T25782	MDL 27324	MDL-27,324,MDL-27324,MDL27,324,MDL 27,324,MDL27324
	MDL 27324 is an inhibitor of human neutrophil elastase.
T26929	BVT173187	BVT 173187,BVT-173187
	BVT173187 is a neutrophil formyl peptide receptors (FPR1) inhibitor.
T25521	Ici 200880	Ici 200,880,Ici-200880,Ici200,880,Ic-200,880,Ici200880
	Ici 200880 is a human neutrophil elastase synthetic peptide inhibitor.
T69790	GW-475151
	GW-475151 inhibits human neutrophil elastase (HNE).
T70219	ISP-VT
	ISP-VT is a Novel inhibitor of COX and neutrophil migration.
T25518	Ici 186756	Ici186756,Ici--186756
	Ici 186756 is a novel, effective, and selective inhibitor of human neutrophil elastase.
T25784L	MDL-101146, (S)-	MDL101146, (S)-
	MDL-101146, (S)- is an effective orally active inhibitor of human neutrophil elastase.
T25784	MDL-101146, (R)-	MDL101146, (R)-
	MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.

Compounds

Rabbit neutrophil peptide 3b

T81316

Synonym:

Target:

Neutrophil elastase inhibitor 4

T79397

Synonym:

Target:

Bovine neutrophil beta-defensin 12

Target: Others, FLAP, Epoxide Hydrolase

Target: Dehydrogenase

Target: IL Receptor, CXCR

Synonym: BMS-986235,LAR-1219

Target: Others, HCV Protease

Binodenoson

T9516

Synonym: WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos

Target: Adenosine Receptor

Synonym: AZD9668,Avelestat

Target: Others, Serine Protease

Sivelestat

T6986

Synonym: ONO5046,EI546,LY544349

Target: Others, SARS-CoV, Serine Protease

Navarixin

T7130

Synonym: MK-7123,SCH 527123

Target: Serine Protease

2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one

T8563

Synonym:

Target: Serine Protease

2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE

T8602

Synonym:

Target: Serine Protease

Synonym: Ac9-25 acetate(284040-76-2 free base)

Target: Calcium Channel, LTR

Synonym: AZD 8309,AZD-8309

Target: Glutathione Peroxidase, CXCR

PMX 53 acetate(219639-75-5 free base)

TP2334

Synonym:

Target: Complement System

Sivelestat sodium tetrahydrate

T20762

Synonym: ONO-5046 sodium tetrahydrate,Elaspol,ONO 5046,ONO5046 sodium tetrahydrate,Elaspol sodium tetrahydrate,ONO-5046,Sivelestat Sodium,Sivelestat Sodium Hydrate,ONO5046

Target: Serine Protease

Cl-amidine hydrochloride

T10831L

Synonym:

Target: Apoptosis, PAD

Sodium Hydrogen Sulfide (hydrate)

Target: Serine Protease

FK706

T15285

Synonym:

Target: Serine Protease

AE-3763

T10254

Synonym:

Target: Serine Protease

Freselestat

T31877

Synonym: ONO-PO 736,ONO-6818,ONO 6818,ONO6818

Target:

MDL 27399

T25783

Synonym: MDL-27,399,MDL 27,399,MDL27399,MDL27,399

Target:

ICI 200355

T25520

Synonym: ICI-200,355,ICI 200,355,ICI-200355,ICI200,355,ICI200355

Target:

MDL 101146

T25781

Synonym: MDL-101146,MD 101,146,MDL101146,MDL 101,146,MDL-101,146

Target:

MDL 27324

T25782

Synonym: MDL-27,324,MDL-27324,MDL27,324,MDL 27,324,MDL27324

Target:

BVT173187

T26929

Synonym: BVT 173187,BVT-173187

Target:

Ici 200880

T25521

Synonym: Ici 200,880,Ici-200880,Ici200,880,Ic-200,880,Ici200880

Synonym: Ici186756,Ici--186756

Target:

MDL-101146, (S)-

T25784L

Synonym: MDL101146, (S)-

Target:

MDL-101146, (R)-

T25784

Synonym: MDL101146, (R)-

Target:

カタログ番号	製品名	別名	ターゲット
TN6737	(25R)-Spirost-4-ene-3,12-dione		Others
	(25R)-Spirost-4-ene-3,12-dione is a natural product.		Others
T13864	Resolvin D1	RvD1	Apoptosis
	Resolvin D1 (RvD1) is an endogenous pro-inflammatory mediator that blocks pro-inflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances macroph...		Apoptosis
TN1006	Tirucallol		NOS , NO Synthase , Prostaglandin Receptor
	Tirucallol is an antiinflammatory agent isolated from Euphorbia lactea.Tirucallol exerts a topical anti-inflammatory effect in vivo, via a mechanism of action related to the neutrophil migration.		NOS , NO Synthase , Prostaglandin Receptor
TJS0314	5,7-Dihydroxy-4-methylcoumarin	Methyl-2H-Chromen-2-One,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin	Others , Antibacterial , Antifungal
	5,7-Dihydroxy-4-methylcoumarin (Methyl-2H-Chromen-2-One) inhibits human neutrophil oxidative metabolism and elastase activity. 5,7-Dihydroxy-4-methylcoumarin has in vitro platelet antiaggregatory property. 5,7-Dihydroxy-...		Others , Antibacterial , Antifungal
T4S2063	Tetrahydrocoptisine	STYLOPINE	ERK , p38 MAPK , NF-κB
	1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may invo...		ERK , p38 MAPK , NF-κB
T6S1572	Sauchinone		ERK , p38 MAPK , NF-κB
	1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...		ERK , p38 MAPK , NF-κB
T13661	Docosatrienoic Acid	cis-13,16,19-docosatrienoic acid,(13Z,16Z,19Z)-13,16,19-Docosatrienoic acid	Others
	Docosatrienoic acid is a rare omega-3 fatty acid; Ki value is 5×M, which inhibits the binding of LTB4 to porcine neutrophil membrane.		Others
TN5880	Mesuol
	Mesuol has antioxidant activity, it shows very high scavenging activity against DPPH radical; it also has immunomodulatory activity, can potentiate percentage neutrophil adhesion in neutrophil adhesion test in rats and p...
T5768	Bruceine B		TNF , Parasite
	Bruceine B, a potent inhibitor of leukocyte-endothelial cell adhesion, may have anti-inflammatory activity, it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated ...		TNF , Parasite
T38097	Antibiotic PF 1052
	Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma.1,2 It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively), among others.1 It inhibits n...
TN4303	Isokaempferide		ATPase , Potassium Channel , Calcium Channel , TNF , Prostaglandin Receptor
	Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by reducing neutrophil degranulation, myeloperoxidase activity, m...
TN5221	(-)-Variabilin
	Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3....
TN5228	Vestitol		Antifection
	Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose of 10 mg/kg, and shows MICs ranging from...		Antifection
TN4584	Morolic acid		IL Receptor , COX , HIV Protease
	Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediat...		IL Receptor , COX , HIV Protease

天然物製品

(25R)-Spirost-4-ene-3,12-dione

Target: NOS, NO Synthase, Prostaglandin Receptor

5,7-Dihydroxy-4-methylcoumarin

TJS0314

Synonym: Methyl-2H-Chromen-2-One,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin

Target: Others, Antibacterial, Antifungal

Tetrahydrocoptisine

T4S2063

Synonym: STYLOPINE

Target: ERK, p38 MAPK, NF-κB

Sauchinone

T6S1572

Synonym:

Target: ERK, p38 MAPK, NF-κB

Docosatrienoic Acid

T13661

Synonym: cis-13,16,19-docosatrienoic acid,(13Z,16Z,19Z)-13,16,19-Docosatrienoic acid

Target: TNF, Parasite

Target: ATPase, Potassium Channel, Calcium Channel, TNF, Prostaglandin Receptor

Target: IL Receptor, COX, HIV Protease

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03660	P67phox Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	p67phox Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 30 kDa and the accession number is AAH01606.1.
TMPY-03619	P67phox Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	p67phox Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 87.6 kDa and the accession number is AAH01606.1.
TMPH-01163	CXCL5 Protein, Human, Recombinant (His)	Human	E. coli
	CXCL5 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-02997	Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO)	Mycobacterium smegmatis	E. coli
	Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ...
TMPJ-00082	NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes w...
TMPJ-00848	NCF1 Protein, Human, Recombinant (His)	Human	E. coli
	Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a mem...
TMPH-02503	DEFA1 Protein, Mouse, Recombinant (GST & His)	Mouse	E. coli
	Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium. DEFA1 Protein, Mouse, Recombinant (GST & His) is expressed in ...
TMPH-01772	DEFA1 Protein, Human, Recombinant (GST)	Human	E. coli
	Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing thei...
TMPH-00794	Dps Protein, Helicobacter pylori, Recombinant (His & SUMO)	Helicobacter pylori	E. coli
	Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ...
TMPH-01773	ELANE Protein, Human, Recombinant (GST)	Human	E. coli
	Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane pro...
TMPJ-00541	CD177 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is express...
TMPH-01070	CD177 Protein, Human, Recombinant (GST & His)	Human	E. coli
	CD177 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 63.6 kDa and the accession number is Q8N6Q3.
TMPH-03751	CYBB Protein, Human, Recombinant (His)	Human	E. coli
	Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membr...
TMPY-00672	Azurocidin/CAP37 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil...
TMPY-01850	CEACAM3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66...
TMPH-02755	LECT2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation. LECT2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular ...
TMPH-03522	Alpha-hemolysin Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	P. pastoris (Yeast)
	Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probabl...
TMPH-03523	Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probabl...
TMPY-01909	Elafin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein ...
TMPY-02847	Moesin Protein, Human, Recombinant (aa 1-346, His)	Human	E. coli
	Moesin is a member of the ERM family which includes ezrin and radixin. ERM proteins, highly related members of the larger protein 4.1 superfamily, can exist in an active or inactive conformation. It seems that ERM protei...
TMPK-01318	CD24 Protein-VLP, Cynomolgus, Recombinant	Cynomolgus	HEK293 Cells
	CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPJ-01060	CXCL6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines...
TMPK-00001	CD24 Protein-VLP, Human, Recombinant	Human	HEK293 Cells
	CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPJ-00833	MPO Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Myeloperoxidase (MPO) is a hemecontaining enzyme belonging to the XPO subfamily of peroxidases. It is an abundant neutrophil and monocyte glycoprotein that catalyzes the hydrogen peroxidedependent conversion of chloride,...
TMPK-00004	CD24 Protein, Human, Recombinant (GST)	Human	E. coli
	CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPK-00674	CD24 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPK-00675	CD24 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated	Cynomolgus	HEK293 Cells
	CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPK-00002	CD24 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPK-00006	CD24 Protein (Primary Amine Labeling), Human, Recombinant (mFc), Biotinylated	Human	HEK293 Cells
	CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPJ-01394	CXCL15 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse C-X-C motif chemokine 15, also known as Cxcl15, is a secreted protein which is member of the ELR motif-containing CXC chemokines. It expressed at low levels in fetal lung, the expression restricted to the lung, pro...
TMPK-00003	CD24 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPK-00005	CD24 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated	Human	HEK293 Cells
	CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPH-03577	Staphopain B Protein, S. aureus, Recombinant (GST)	Staphylococcus aureus	E. coli
	Cysteine protease that plays an important role in the inhibition of host innate immune response. Degrades host elastin, fibrogen, fibronectin and kininogen. Blocks phagocytosis of opsonised S. aureus by neutrophils and m...
TMPJ-00582	PRG3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain. Proteoglycans are a major component of the animal extracellular ...
TMPH-02658	FPR1 Protein, Mouse, Recombinant (GST & His & Myc)	Mouse	E. coli
	High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release...
TMPY-05252	Myeloperoxidase/MPO Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction. Myeloperoxidase (MPO) is an important en...
TMPH-01346	FPR1 Protein, Human, Recombinant (GST & His & Myc)	Human	E. coli
	High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release...
TMPH-02659	FPR2 Protein, Mouse, Recombinant (GST & His & Myc)	Mouse	E. coli
	High affinity receptor for N-formyl-methionyl peptides (FMLP), which are powerful neutrophil chemotactic factors. Stimulates chemotaxis in immune cells to site of infection or tissue damage upon recognition of several li...
TMPH-03578	SCIN Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a ...
TMPH-03296	Galectin-3/LGALS3 Protein, Rat, Recombinant (His)	Rat	E. coli
	Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute infl...
TMPJ-00006	CXCL1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor. The N-terminal ...
TMPY-00517	LSP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LSP1 (Lymphocyte Specific Protein 1) is a Protein Coding gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regula...
TMPJ-00760	CXCL7 Protein, Human, Recombinant	Human	E. coli
	Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domai...
TMPH-01214	DNASE1L3 Protein, Human, Recombinant	Human	E. coli
	Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA...
TMPH-01212	DNASE1L3 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA...
TMPH-01213	DNASE1L3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA...
TMPJ-00011	CXCL2 Protein, Mouse, Recombinant	Mouse	E. coli
	C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin...
TMPJ-00382	P-selectin Protein, Mouse, Recombinant (Avi & His), Biotinylated	Mouse	HEK293 Cells
	P-selectin/CD62P is a single-pass type I membrane protein which is a member of the Selectin family. It consists 768 amino acid (aa). P-selectin is a cell surface glycoprotein expressed by activated platelets and endothel...
TMPY-02908	BPI Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Bactericidal/permeability-increasing protein is a member of the BPI/LBP/Plunc superfamily and BPI/LBP family. It is a cationic protein which can be detected in the azurophilic granule and on the surface of polymorphonucl...
TMPJ-00527	SP-D Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognitio...
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