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155

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T19417	Urinary Incontinence-Targeting Compound 1		Others
	Urinary Incontinence-Targeting Compound 1, used in the research of urinary incontinence, is a sulfonanilide derivative.		Others
T76240	Urinary Trypsin Inhibitor Fragment
	Urinary Trypsin Inhibitor Fragment, a proteolytically derived segment of urinary trypsin inhibitor, demonstrates the capability to inhibit tumor cell invasion through limited proteolysis [1].
T1049L	Oxybutynin	Oxytrol,Ditropan,Oxibutyninum	Potassium Channel , AChR
	Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.		Potassium Channel , AChR
T1049	Oxybutynin chloride	Oxybutynin hydrochloride,Oxybutynin HCl	Potassium Channel , AChR
	Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.		Potassium Channel , AChR
T8365	Methenamine Hippurate		Antibacterial
	Methenamine Hippurate is a component of Hiprex, with antibacterial activity.		Antibacterial
T8133	SulfadiMethoxine sodium		Anti-infection , Antibacterial , Antibiotic
	Sulfadimethoxine is a antimicrobial agent, treatment of respiratory, urinary tract, enteric, and soft tissue infections		Anti-infection , Antibacterial , Antibiotic
T1078	Sulfadimethoxine	Sulphadimethoxine	Antibacterial , Antibiotic
	Sulfadimethoxine (Sulphadimethoxine) is a sulfanilamide that is used as an anti-infective agent.		Antibacterial , Antibiotic
T1444	Lomefloxacin	SC47111A	Topoisomerase , Antibacterial , Antibiotic
	Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.		Topoisomerase , Antibacterial , Antibiotic
T5513	RO-3		P2X Receptor
	RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor		P2X Receptor
T16789	Rosoxacin	Acrosoxacin	Antibacterial , Antibiotic
	Rosoxacin (Acrosoxacin) shows antibacterial activities against a broad spectrum of Gram-negative bacteria including Neisseria gonorrhoeae (MIC90 = 0.03mg/ml).		Antibacterial , Antibiotic
T3126	Bethanechol chloride	(±)-Bethanechol,Urecholine,Myocholine,Carbamyl-β-methylcholine chloride	AChR
	Bethanechol chloride (Carbamyl-β-methylcholine chloride) is a slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following ab...		AChR
T5023	Propiverine hydrochloride		Others , Calcium Channel , AChR
	Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).		Others , Calcium Channel , AChR
T0748	Sulfameter	5-Methoxysulfadiazine,Sulfametoxydiazine	DHFR , Antibacterial , Antibiotic
	Sulfameter (Sulfametoxydiazine) is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and leprosy.		DHFR , Antibacterial , Antibiotic
T0116	Balofloxacin		DNA gyrase , Antibacterial , Antibiotic
	Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase.		DNA gyrase , Antibacterial , Antibiotic
T5521	Bropirimine	U-54461	TLR
	Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.		TLR
T0274	Cinoxacin	Compound 64716	Topoisomerase , Antibacterial , Antibiotic
	Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics. Its activity was similar to oxolinic acid and nalidixic acid.		Topoisomerase , Antibacterial , Antibiotic
T1070	Cefmetazole sodium	Sodium cefmetazole	Antibacterial , Antibiotic
	Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types...		Antibacterial , Antibiotic
T10952	Dabuzalgron	Ro 115-1240	Apoptosis , Adrenergic Receptor
	Dabuzalgron (Ro 115-1240) is an orally active selective alpha-1A adrenergic receptor agonist used to treat urinary incontinence. Dabuzaron prevents cardiotoxicity caused by doxorubicin by maintaining mitochondrial functi...		Apoptosis , Adrenergic Receptor
T0396	Pipemidic acid	Acido pipemidico	Antibacterial , Antibiotic
	Pipemidic acid (Acido pipemidico), a new antibacterial agent, inhibits the activity of Pseudomonas aeruginosa.		Antibacterial , Antibiotic
T1472	Trospium chloride	Spasmex,Sanctura	AChR
	Trospium chloride (Spasmex) is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome. Trospium chloride has not been implicated in causing liver enzyme elevations o...		AChR
T0601	Monobenzyl phthalate	Phthalic Acid Monobenzyl Ester	Others , Endogenous Metabolite
	Monobenzyl phthalate (Phthalic Acid Monobenzyl Ester) is Phthalate metabolite.		Others , Endogenous Metabolite
T6349	Sitafloxacin Hydrate	DU-6859a,DU6859a hydrate	Antibacterial , Antibiotic
	Sitafloxacin Hydrate (DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer.		Antibacterial , Antibiotic
T1625	Lomefloxacin hydrochloride	Lomefloxacin HCl,Okacyn,Maxaquin	Topoisomerase , Antibacterial , Antibiotic
	Lomefloxacin hydrochloride (Okacyn) inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during...		Topoisomerase , Antibacterial , Antibiotic
T8139	Sulfamethoxazole sodium	Ro 4-2130 sodium	Others , Antibacterial , Antibiotic
	Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic		Others , Antibacterial , Antibiotic
T0099	Tolterodine tartrate	Detrol LA,PNU-200583E,Kabi-2234	AChR
	Tolterodine tartrate (PNU-200583E) is a potent antagonist for muscarinic receptor. It show selectivity for the urinary bladder and salivary glands in vivo.		AChR
T1233	Oxolinic acid	Emyrenil,Nidantin,NSC 110364,Dioxacin,Urinox	Dopamine Receptor , DNA/RNA Synthesis , Antibacterial , Antibiotic
	Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
T5189	Omadacycline	PTK 0796,Amadacycline	ribosome , Antibacterial , Antibiotic
	Omadacycline (Amadacycline), a new tetracycline antibiotic, can inhibit the 30s subunit of bacterial ribosome.		ribosome , Antibacterial , Antibiotic
T1504	Silodosin	KAD 3213,KMD 3213	Adrenergic Receptor
	Silodosin (KAD 3213) is an alpha-Adrenergic Blocker. The mechanism of action of silodosin is as an Adrenergic alpha-Antagonist.		Adrenergic Receptor
T0703	Flavoxate hydrochloride	Flavoxate HCl,NSC-114649,DW61,Rec-7-0040	AChR
	Flavoxate hydrochloride (DW61) , a muscarinic AChR antagonist, is used in the therapy of various urinary syndromes and as an antispasmodic.		AChR
T38565	Testosterone glucuronide		Others
	Testosterone glucuronide is the major urinary metabolite of testosterone and is a potential urinary biomarker.		Others
T0400	Nitroxoline	5-Nitro-8-quinolinol,8-Hydroxy-5-nitroquinoline,5-Nitro-8-hydroxyquinoline,5-nitroquinolin-8-ol	Antibacterial , Antibiotic , Autophagy
	Nitroxoline (5-nitroquinolin-8-ol) is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections.		Antibacterial , Antibiotic , Autophagy
T11305	Flurofamide		Others
	Flurofamide is an effective bacterial urease inhibitor and has potential in the treatment of infected urinary calculi.		Others
T4273	Furagin	F-35,Akritoin,Furazidine,NF-416,Furazidin	Antibacterial
	Furagin (Furazidine) is a Nitrofuran derivative with anti-infective activity used for urinary tract infections.		Antibacterial
T2184	Sulfachloropyridazine	Sulfachlorpyridazine	Antibacterial , Antibiotic
	Sulfachloropyridazine (Sulfachlorpyridazine) is a sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.		Antibacterial , Antibiotic
T13881	Dicirenone	SC26304	ATPase , Glucocorticoid Receptor
	Dicirenone (SC26304) inhibits the Mineralocorticoid receptor (MR), aldosterone regulation of the urinary K+:Na+ ratio, and aldosterone binding to renal cytoplasmic and nuclear receptors.		ATPase , Glucocorticoid Receptor
T28257L	(-)-OPC-51803		AChR
	(-)-OPC-51803 is an antidiuretic hormone V2 receptor agonist used in the treatment of nocturia and urinary incontinence.		AChR
T1534	Darifenacin hydrobromide	Darifenacin HBr,UK-88525	AChR
	Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.		AChR
T29687	Afacifenacin	Afacifenacin fumarate,SMP-986,NS 986,NS-986,SMP 986,NS986,SMP986	AChR
	Afacifenacin (SMP-986) fumarate is an M3 muscarinic receptor-selective antagonist used in the study of ischemic heart disease, urinary incontinence and cystitis and other disorders.		AChR
T0026	Sulfalene	Sulfalene(SMPZ),Sulfalen,SMP2,Butadiene sulfone,AS-18908,Sulfametopyrazine,3-Sulfolene	Antibacterial , Antibiotic , Parasite , Autophagy
	Sulfalene (SMP2), a long-acting sulfonamide antibiotic, is used for the therapy of chronic bronchitis, urinary tract infections, and malaria.		Antibacterial , Antibiotic , Parasite , Autophagy
T22316	Doxazosin	UK 33274	Adrenergic Receptor
	Doxazosin (UK 33274) is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms.		Adrenergic Receptor
T9420	Prifinium bromide		Others
	Prifinium bromide is a quaternary ammon antimuscarinic. It inhibits hyperkinesia of the digestive organs and urinary tract and has a spasmolytic action.		Others
TP1819L	Substance P 1-9 aceate		Neurotensin Receptor
	Substance P 1-9 aceate is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.		Neurotensin Receptor
T0111	Solifenacin succinate	YM905	AChR
	Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the treatment of URINARY INCONTINENCE.		AChR
T0087L	Sulfacetamide sodium	Sulamyd sodium	Antibacterial , Antibiotic , Autophagy
	Sulfacetamide sodium (Sulamyd sodium) is an anti-infective agent. It is used topically to treat orally for urinary tract infections and skin infections.		Antibacterial , Antibiotic , Autophagy
T28257	OPC-51803	SOU-003,SOU 003,SOU003,OPC51803,OPC 51803	Vasopressin Receptor
	OPC-51803 is an orally available nonapeptidylpressor (AVP) V(2) receptor selective agonist for the treatment of urinary incontinence and nocturia.		Vasopressin Receptor
T19794	Temafloxacin	Omniflox	Antibiotic
	Temafloxacin (Omniflox) is an antibiotic and antimycobacterial agent. It used to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.		Antibiotic
T0170	Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (9CI)	phosphonomycin calcium,Fosfomycin calcium,phosphomycin calcium	Antibiotic
	Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (9CI) (phosphonomycin calcium) is an antibiotic, used for the treatment of urinary tract infections and intestinal infections caused by susceptible strains.		Antibiotic
T8802	2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-	2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-fur	Serine Protease
	2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urine or synthetically produced.		Serine Protease
T8134	Cefathiamidine		Antibacterial , Antibiotic
	Cefathiamidine exhibits a wide spectrum of antimicrobial activity against bacteria. Cefathiamidine is used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis		Antibacterial , Antibiotic
T1460	Dicyclomine hydrochloride		AChR
	Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence.		AChR

Compounds

Urinary Incontinence-Targeting Compound 1

T19417

Synonym:

Target: Others

Urinary Trypsin Inhibitor Fragment

Synonym: Oxytrol,Ditropan,Oxibutyninum

Target: Potassium Channel, AChR

Oxybutynin chloride

T1049

Synonym: Oxybutynin hydrochloride,Oxybutynin HCl

Target: Potassium Channel, AChR

Methenamine Hippurate

T8365

Synonym:

Target: Antibacterial

SulfadiMethoxine sodium

T8133

Synonym:

Target: Anti-infection, Antibacterial, Antibiotic

Sulfadimethoxine

T1078

Synonym: Sulphadimethoxine

Target: Antibacterial, Antibiotic

Lomefloxacin

T1444

Synonym: SC47111A

Target: Topoisomerase, Antibacterial, Antibiotic

Target: Antibacterial, Antibiotic

Bethanechol chloride

T3126

Synonym: (±)-Bethanechol,Urecholine,Myocholine,Carbamyl-β-methylcholine chloride

Target: AChR

Propiverine hydrochloride

T5023

Synonym:

Target: Others, Calcium Channel, AChR

Sulfameter

T0748

Synonym: 5-Methoxysulfadiazine,Sulfametoxydiazine

Target: DHFR, Antibacterial, Antibiotic

Balofloxacin

T0116

Synonym:

Target: DNA gyrase, Antibacterial, Antibiotic

Synonym: Compound 64716

Target: Topoisomerase, Antibacterial, Antibiotic

Cefmetazole sodium

T1070

Synonym: Sodium cefmetazole

Target: Antibacterial, Antibiotic

Dabuzalgron

T10952

Synonym: Ro 115-1240

Target: Apoptosis, Adrenergic Receptor

Pipemidic acid

T0396

Synonym: Acido pipemidico

Target: Antibacterial, Antibiotic

Trospium chloride

T1472

Synonym: Spasmex,Sanctura

Target: AChR

Monobenzyl phthalate

T0601

Synonym: Phthalic Acid Monobenzyl Ester

Target: Others, Endogenous Metabolite

Sitafloxacin Hydrate

T6349

Synonym: DU-6859a,DU6859a hydrate

Target: Antibacterial, Antibiotic

Lomefloxacin hydrochloride

T1625

Synonym: Lomefloxacin HCl,Okacyn,Maxaquin

Target: Topoisomerase, Antibacterial, Antibiotic

Sulfamethoxazole sodium

T8139

Synonym: Ro 4-2130 sodium

Target: Others, Antibacterial, Antibiotic

Tolterodine tartrate

T0099

Synonym: Detrol LA,PNU-200583E,Kabi-2234

Target: AChR

Oxolinic acid

T1233

Synonym: Emyrenil,Nidantin,NSC 110364,Dioxacin,Urinox

Target: Dopamine Receptor, DNA/RNA Synthesis, Antibacterial, Antibiotic

Omadacycline

T5189

Synonym: PTK 0796,Amadacycline

Target: ribosome, Antibacterial, Antibiotic

Silodosin

T1504

Synonym: KAD 3213,KMD 3213

Target: Adrenergic Receptor

Flavoxate hydrochloride

T0703

Synonym: Flavoxate HCl,NSC-114649,DW61,Rec-7-0040

Target: AChR

Testosterone glucuronide

Synonym: 5-Nitro-8-quinolinol,8-Hydroxy-5-nitroquinoline,5-Nitro-8-hydroxyquinoline,5-nitroquinolin-8-ol

Target: Antibacterial, Antibiotic, Autophagy

Synonym: F-35,Akritoin,Furazidine,NF-416,Furazidin

Target: Antibacterial

Sulfachloropyridazine

T2184

Synonym: Sulfachlorpyridazine

Target: Antibacterial, Antibiotic

Dicirenone

T13881

Synonym: SC26304

Target: ATPase, Glucocorticoid Receptor

Darifenacin hydrobromide

T1534

Synonym: Darifenacin HBr,UK-88525

Target: AChR

Afacifenacin

T29687

Synonym: Afacifenacin fumarate,SMP-986,NS 986,NS-986,SMP 986,NS986,SMP986

Target: AChR

Sulfalene

T0026

Synonym: Sulfalene(SMPZ),Sulfalen,SMP2,Butadiene sulfone,AS-18908,Sulfametopyrazine,3-Sulfolene

Target: Antibacterial, Antibiotic, Parasite, Autophagy

Doxazosin

T22316

Synonym: UK 33274

Target: Adrenergic Receptor

Substance P 1-9 aceate

TP1819L

Synonym:

Target: Neurotensin Receptor

Solifenacin succinate

Synonym: Sulamyd sodium

Target: Antibacterial, Antibiotic, Autophagy

OPC-51803

T28257

Synonym: SOU-003,SOU 003,SOU003,OPC51803,OPC 51803

Target: Vasopressin Receptor

Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (9CI)

T0170

Synonym: phosphonomycin calcium,Fosfomycin calcium,phosphomycin calcium

Target: Antibiotic

2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-

T8802

Synonym: 2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-fur

Target: Serine Protease

Cefathiamidine

T8134

Synonym:

Target: Antibacterial, Antibiotic

Dicyclomine hydrochloride

T1460

Synonym:

Target: AChR

カタログ番号	製品名	別名	ターゲット
T10815	Cinnamoylglycine		Endogenous Metabolite
	Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in humans. It is used as a potential urinary biomarker.		Endogenous Metabolite
T9599	3,4,5-Trimethoxybenzaldehyde		Anti-infection , Antibacterial
	3,4,5-Trimethoxybenzaldehyde shows anti-Candida efficacy and inhibits adhesion and biofilms.		Anti-infection , Antibacterial
T8126	Cefodizime Sodium		Others , Antibacterial , Antibiotic
	Cefodizime Sodium is a third generation cephalosporin antibiotic, has broad-spectrum activity		Others , Antibacterial , Antibiotic
T10021	1-Methylxanthine		Endogenous Metabolite
	1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.		Endogenous Metabolite
T1313	Nitrofurantoin	Furadantine,Macrodantin,Furadonine	Antibacterial , Antibiotic
	Nitrofurantoin (Furadantine), an antibiotic, inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoi...		Antibacterial , Antibiotic
T0613	3-Hydroxyisovaleric acid	Beta-Hydroxyisovaleric acid	Others , Endogenous Metabolite
	3-Hydroxyisovaleric acid (Beta-Hydroxyisovaleric acid) is an endogenous metabolite excreted in the urine and can serve as an early and sensitive indicator of biotin deficiency.		Others , Endogenous Metabolite
T1153	Trimethoprim	NIH 204,BW 56-72,NSC-106568	DHFR , DNA/RNA Synthesis , Antifolate , Antibacterial , Antibiotic
	Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Tra...
T4456	N4-Acetylcytidine	N-Acetylcytidine	Others , Endogenous Metabolite
	N4-Acetylcytidine (N-Acetylcytidine) is a modified nucleoside. N4-acetylcytidine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary nucleosides are biological mark...		Others , Endogenous Metabolite
TQ0193	N2,N2-Dimethylguanosine		Endogenous Metabolite
	N2,N2-Dimethylguanosine is an urinary nucleoside. The mean levels of urinary N2,N2-Dimethylguanosine in patients with colorectal cancer are significantly higher than those in patients with intestinal villous adenoma or h...		Endogenous Metabolite
TN7107	S-(2-Carboxypropyl)cysteine		Endogenous Metabolite
	S-(2-Carboxypropyl)cysteine is a urinary metabolite of S-(2-Carboxypropyl)glutathione.		Endogenous Metabolite
T4853	TRIA-662	3-Carbamoyl-1-methylpyridinium Chloride,1-Methylnicotinamide chloride,1-methylpyridin-1-ium-3-carboxamide hydrochloride,Nicotinamide Chloromethylate	Others , Endogenous Metabolite
	TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system.		Others , Endogenous Metabolite
T7154	Trans-trans-Muconic acid		Endogenous Metabolite
	trans-trans-Muconic acid is a urinary metabolite of benzene.		Endogenous Metabolite
T5233	N-Methylnicotinamide	N'-Methylnicotinamide,Nicotinic Acid Methylamide,N-Methylpyridine-3-carboxamide	Others , Endogenous Metabolite
	N-Methylnicotinamide (Nicotinic Acid Methylamide) is a metabolite of niacin (or nicotinamide) and is commonly found in human urine. However low levels of urinary excretion of N-Methylnicotinamide (Nicotinic Acid Methylam...		Others , Endogenous Metabolite
T6599	N6-methyladenosine	N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A	Others , Influenza Virus , Endogenous Metabolite
	N6-methyladenosine (NSC-29409) is a methylated adenine residue. N6-Methyladenosine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary nucleosides are biological ma...		Others , Influenza Virus , Endogenous Metabolite
T5984	Indole-3-carboxylic acid	3-Indoleformic acid	Endogenous Metabolite
	Indole-3-carboxylic acid (3-Indoleformic acid) is a normal urinary indolic tryptophan metabolite .		Endogenous Metabolite
T3A2467	Allocryptopine	Thalictrimine,Fagarine I	Potassium Channel
	Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.		Potassium Channel
T4816	6-Hydroxynicotinic acid	6-Hydroxypyridine-3-carboxylic acid,2-Hydroxy-5-pyridinecarboxylic acid	Others , Endogenous Metabolite
	6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) is exploited in the use of NMR spectroscopy or gas chromatography--mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract infection. A...		Others , Endogenous Metabolite
T8075	1,3-Dimethyluric acid		Endogenous Metabolite
	1,3-Dimethyluric acid is a product of theophylline metabolism in man. It is one of the purine components in urinary calculi.		Endogenous Metabolite
T6567	Levofloxacin	Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin	Topoisomerase , Antibacterial , Antibiotic
	Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.		Topoisomerase , Antibacterial , Antibiotic
T0543	7-Methylxanthine	Heteroxanthine,Heteroxanthin	Nucleoside Antimetabolite/Analog , Endogenous Metabolite
	7-Methylxanthine (Heteroxanthine), a methyl derivative of xanthine, is one of the purine components in urinary calculi. 7-Methylxanthine appears to prevent FDM in pigmented rabbits by remodeling the posterior sclera.		Nucleoside Antimetabolite/Analog , Endogenous Metabolite
T16542	Piromidic acid		Antibacterial , Antibiotic
	Piromidic acid is an antibacterial agent. Piromidic acid is active against gramnegative bacteria and staphylococci. It is used for urinary tract and intestinal infections.		Antibacterial , Antibiotic
T4107	4-Pyridoxic Acid	Pyridoxic Acid,4-Pyridoxinsaeure	Endogenous Metabolite
	4-Pyridoxic Acid (4-Pyridoxinsaeure), a catabolite of vitamin B6, is a water-soluble B-group vitamin that can be used as a urinary diagnostic biomarker for determining the nutritional status of these vitamins.		Endogenous Metabolite
T0738	Urea	Ureophil,Carbamide,E-Cardamoni,Carbonyldiamide	Others , DHFR , Wnt/beta-catenin , Arginase , Endogenous Metabolite , Carbonic Anhydrase
	Urea (Carbonyldiamide) is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for about one-half of the total urinary solids.
T1630	Tiopronin	Thiopronine,Acadione,Captimer	ROS
	Tiopronin (Acadione), a sulfhydryl acylated derivative of glycine, leads to a reduction in urinary cystine concentration and subsequently reduces cystine stone formation.		ROS
T1571	Estriol	NSC-12169,Oestriol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , MRP , Endogenous Metabolite
	Estriol (Oestriol) is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, a large amount of estriol is...
T0983	Penicillamine	d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine	Antibiotic
	Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl a...		Antibiotic
T5275	2,5-Furandicarboxylic acid	Dehydromucic Acid,2,5-Dicarboxyfuran	Others , Endogenous Metabolite
	2,5-Furandicarboxylic acid (Dehydromucic Acid) is a normal urinary metabolite in humans. 2,5-Furandicarboxylic acid is also a microbial metabolite, a product of the oxidation of hydroxymethylfurfural (HMF) by the enzyme ...		Others , Endogenous Metabolite
T5309	Dimethylamine hydrochloride	N,N-Dimethylamine	Others
	Dimethylamine hydrochloride (N,N-Dimethylamine) is abundantly present in human urine. Main sources of urinary dimethylamine have been reported to include trimethylamine N-oxide, a common food component, and asymmetric d...		Others
T5246	Trans-2-butene-1,4-dicarboxylic acid	trans-2-Butene-1,4-dicarboxylic Acid,3-Hexenedioic Acid,trans-3-Hexenedioic Acid,β-Hydromuconic Acid	Others , Endogenous Metabolite
	Trans-2-butene-1,4-dicarboxylic acid (3-Hexenedioic Acid) is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disorde...		Others , Endogenous Metabolite
T5231	2-Methylsuccinic acid	Pyrotartaric Acid,Methylbutanedioic acid	Others , Endogenous Metabolite
	2-Methylsuccinic acid (Pyrotartaric Acid) is a normal metabolite found in human fluids. Increased urinary levels of 2-Methylsuccinic acid (Pyrotartaric Acid) (together with ethylmalonic acid) are the main biochemical mea...		Others , Endogenous Metabolite
T6S0119	Dauricine		Apoptosis , Others , NF-κB
	1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important ro...		Apoptosis , Others , NF-κB
T37508	Meconin		Endogenous Metabolite
	Meconin, a noscapine metabolite, is a urinary detection marker for illicit opiate misuse. This product is intended for use as a forensic standard.		Endogenous Metabolite
T5250	Levoglucosan	1,6-anhydro-b-D-Glucose	Others , Endogenous Metabolite
	Levoglucosan (1,6-anhydro-b-D-Glucose) is an anhydrohexose that is the 1,6-anhydro-derivative of beta-D-glucopyranose. It is formed from the pyrolysis of carbohydrates, such as starch and cellulose. Levoglucosan can also...		Others , Endogenous Metabolite
T4716	Pyrrole-2-carboxylic acid	2-Pyrrolecarboxylic acid,Minaline	Endogenous Metabolite
	Pyrrole-2-carboxylic acid (Minaline) was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase. The latter rela...		Endogenous Metabolite
T15011	Creatine riboside		Others
	Creatine riboside, a urinary metabolite, is a diagnostic and prognostic biomarker of lung cancer.		Others
T36472	Tetrahydro-11-deoxy Cortisol
	Tetrahydro-11-deoxy cortisol (THS) is the primary urinary metabolite of 11-deoxycortisol. Urinary excretion of THS is elevated in patients with 11β-hydroxylase deficiency, a condition resulting from mutations in the cyto...
T19576	Tetrahydrocortisone		Others
	Tetrahydrocortisone, a stress-induced hormone and a urinary metabolite of Cortisone, originates from the reduction of Cortisone facilitated by 5-reductase.		Others
T13978	(S)-3,4-Dihydroxybutyric acid		Others
	(S)-3,4-Dihydroxybutyric acid is a human urinary metabolite.		Others
T17057	Tetrahydrocortisol		Others
	The urinary Tetrahydrocortisol/Tetrahydrocortisone ratio decreases with increasing 11β-hydroxysteroid dehydrogenase activity. Tetrahydrocortisol is cortisol metabolite.		Others
T40381	2,8-Dihydroxyadenine
	2,8-Dihydroxyadenine, an endogenous metabolite, can induce the generation of urinary crystals and nephrolithiasis. Moreover, 2,8-Dihydroxyadenine serves as a diagnostic tool for detecting adenine phosphoribosyltransferas...
T39836	Monoethyl phthalate
	Monoethyl phthalate is a metabolite of diethyl phthalate, serving as a urinary biomarker for phthalate exposure, and indicating potential risks of thyroid cancer and benign nodules.
TN6028	Gardneramine
	Gardneramine has a mild central depressive effect. Gardneramine and hirsutine show a local anesthetic action, they also can inhibit the ganglionic transmission of the dog urinary bladder and that the blockade of the nico...
T38954	L-Glyceric acid sodium
	L-Glyceric acid sodium is a urinary metabolite predominantly found in individuals with the rare inherited metabolic disorder, L-glyceric aciduria. This compound serves as a diagnostic tool for identifying primary hyperox...
T37710	5-Hydroxyoxindole		Reactive Oxygen Species
	5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activit...		Reactive Oxygen Species
T81117	Spilanthol
	Spilanthol, an orally active compound with analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial, and insecticidal properties, facilitates the induction of cAMP, thereby in...
TN4382	Kazinol A		AMPK , mTOR
	Kazinol A shows strong inhibition of arachidonic acid (AA)-induced platelet aggregation. It also exhibits potent inhibition with IC50 values ranging 0.6-164 M against XOD. Kazinol A may be a candidate for the development...		AMPK , mTOR

天然物製品

Cinnamoylglycine

T10815

Synonym:

Target: Endogenous Metabolite

3,4,5-Trimethoxybenzaldehyde

T9599

Synonym:

Target: Anti-infection, Antibacterial

Cefodizime Sodium

T8126

Synonym:

Target: Others, Antibacterial, Antibiotic

1-Methylxanthine

T10021

Synonym:

Target: Endogenous Metabolite

Nitrofurantoin

T1313

Synonym: Furadantine,Macrodantin,Furadonine

Target: Antibacterial, Antibiotic

3-Hydroxyisovaleric acid

T0613

Synonym: Beta-Hydroxyisovaleric acid

Target: Others, Endogenous Metabolite

Trimethoprim

T1153

Synonym: NIH 204,BW 56-72,NSC-106568

Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic

N4-Acetylcytidine

T4456

Synonym: N-Acetylcytidine

Target: Others, Endogenous Metabolite

N2,N2-Dimethylguanosine

TQ0193

Synonym:

Target: Endogenous Metabolite

S-(2-Carboxypropyl)cysteine

TN7107

Synonym:

Target: Endogenous Metabolite

TRIA-662

T4853

Synonym: 3-Carbamoyl-1-methylpyridinium Chloride,1-Methylnicotinamide chloride,1-methylpyridin-1-ium-3-carboxamide hydrochloride,Nicotinamide Chloromethylate

Target: Others, Endogenous Metabolite

trans-trans-Muconic acid

T7154

Synonym:

Target: Endogenous Metabolite

N-Methylnicotinamide

T5233

Synonym: N'-Methylnicotinamide,Nicotinic Acid Methylamide,N-Methylpyridine-3-carboxamide

Target: Others, Endogenous Metabolite

N6-methyladenosine

T6599

Synonym: N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A

Target: Others, Influenza Virus, Endogenous Metabolite

Indole-3-carboxylic acid

T5984

Synonym: 3-Indoleformic acid

Target: Endogenous Metabolite

Allocryptopine

T3A2467

Synonym: Thalictrimine,Fagarine I

Target: Potassium Channel

6-Hydroxynicotinic acid

T4816

Synonym: 6-Hydroxypyridine-3-carboxylic acid,2-Hydroxy-5-pyridinecarboxylic acid

Target: Others, Endogenous Metabolite

1,3-Dimethyluric acid

T8075

Synonym:

Target: Endogenous Metabolite

Levofloxacin

T6567

Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin

Target: Topoisomerase, Antibacterial, Antibiotic

7-Methylxanthine

T0543

Synonym: Heteroxanthine,Heteroxanthin

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Piromidic acid

T16542

Synonym:

Target: Antibacterial, Antibiotic

4-Pyridoxic Acid

T4107

Synonym: Pyridoxic Acid,4-Pyridoxinsaeure

Target: Endogenous Metabolite

Urea

T0738

Synonym: Ureophil,Carbamide,E-Cardamoni,Carbonyldiamide

Target: Others, DHFR, Wnt/beta-catenin, Arginase, Endogenous Metabolite, Carbonic Anhydrase

Tiopronin

T1630

Synonym: Thiopronine,Acadione,Captimer

Target: ROS

Estriol

T1571

Synonym: NSC-12169,Oestriol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, MRP, Endogenous Metabolite

Penicillamine

T0983

Synonym: d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine

Target: Antibiotic

2,5-Furandicarboxylic acid

T5275

Synonym: Dehydromucic Acid,2,5-Dicarboxyfuran

Target: Others, Endogenous Metabolite

Dimethylamine hydrochloride

T5309

Synonym: N,N-Dimethylamine

Target: Others

Trans-2-butene-1,4-dicarboxylic acid

T5246

Synonym: trans-2-Butene-1,4-dicarboxylic Acid,3-Hexenedioic Acid,trans-3-Hexenedioic Acid,β-Hydromuconic Acid

Target: Others, Endogenous Metabolite

2-Methylsuccinic acid

T5231

Synonym: Pyrotartaric Acid,Methylbutanedioic acid

Target: Others, Endogenous Metabolite

Dauricine

T6S0119

Synonym:

Target: Apoptosis, Others, NF-κB

Meconin

T37508

Synonym:

Target: Endogenous Metabolite

Levoglucosan

T5250

Synonym: 1,6-anhydro-b-D-Glucose

Target: Others, Endogenous Metabolite

Pyrrole-2-carboxylic acid

T4716

Synonym: 2-Pyrrolecarboxylic acid,Minaline

Target: Endogenous Metabolite

Tetrahydro-11-deoxy Cortisol

(S)-3,4-Dihydroxybutyric acid

L-Glyceric acid sodium

Target: Reactive Oxygen Species

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00155	Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated	Human	HEK293 Cells
	Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also ...
TMPH-02832	Serpin A5 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extr...
TMPH-02046	Ribonuclease 7 Protein, Human, Recombinant (His)	Human	E. coli
	Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus f...
TMPK-00967	DSG-2/Desmoglein-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells...
TMPK-00736	DSG-2/Desmoglein-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells...
TMPH-01508	HABP2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fib...
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPY-04171	MFAP3 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	MFAP3 (Microfibril Associated Protein 3) is a Protein Coding gene. The human gene encoding MFAP3 has a very simple structure, containing only two translated exons encoding a protein of 362 amino acids. The gene was found...
TMPJ-01116	HABP2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Hyaluronan-binding protein 2（HABP2） is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50...
TMPJ-00490	Serpin A5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i...
TMPY-02220	HRAS Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	HRas, also known as HRAS, belongs to the small GTPase superfamily, Ras family, and is widely expressed. It functions in signal transduction pathways. HRas can bind GTP and GDP, and they have intrinsic GTPase activity. It...