| T5S2129 |
Sciadopitysin
|
|
TNF
,
NF-κB
|
|
Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in o... |
| T4S2126 |
Ginkgetin
|
|
Apoptosis
,
Wnt/beta-catenin
,
COX
,
STAT
,
Autophagy
|
|
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ... |
| T2808 |
Bilobalide
|
(-)-Bilobalide |
Apoptosis
,
Endogenous Metabolite
,
Autophagy
|
|
Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations. |
| T2751 |
Ginkgolide B
|
BN-52021 |
Apoptosis
,
PAFR
,
Endogenous Metabolite
|
|
Ginkgolide B (BN-52021) is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba. |
| T2749 |
Ginkgolide A
|
BN-52020 |
GABA Receptor
,
Endogenous Metabolite
|
|
Ginkgolide A (BN-52020) is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders. |
| TN2373 |
(E/Z)-Ginkgolic acid C17:2
|
Ginkgolic Acid C17:2 |
Dehydrogenase
|
|
(E/Z)-Ginkgolic acid C17:2 (Ginkgolic Acid C17:2) is a natural product that can be extracted from Ginkgo biloba and targets human dihydroorotic acid dehydrogenase (DHODH). |
| T8200 |
Ginkgolide K
|
|
AMPK
,
Autophagy
|
|
Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity. |
| T6S2123 |
Ginkgolic Acid
|
Romanicardic acid,Ginkgolic acid I,Ginkgolic acid (15:1),Ginkgolic acid C15:1 |
Others
,
E1/E2/E3 Enzyme
|
|
Ginkgolic Acid (Romanicardic acid) C15:1 represses curli genes and prophage genes in EHEC. |
| T6S2122 |
Ginkgolic Acid (C13:0)
|
6-Tridecylsalicylic acid,Ginkgolic acid (13:0),Ginkgoneolic Acid,Ginkgolic acid C13:0 |
Antibacterial
,
Glucosidase
|
|
Ginkgolic Acid (C13:0) (6-Tridecylsalicylic acid): 0exhibits the highest α-glucosidase inhibitory activity. |
| T6S2116 |
Ginkgolic acid C17:1
|
|
Phosphatase
,
PTEN
|
|
1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes. |
| T2750 |
Ginkgolide C
|
BN-52022 |
MMP
,
Sirtuin
,
Endogenous Metabolite
,
AMPK
|
|
Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body. |
| T6S2115 |
Ginkgolide J
|
BN 52024,7-beta-Hydroxyginkgolide A |
PDE
|
|
Ginkgolide J (BN 52024) has neuroprotective activity, it can prevent A beta(1-42) induced inhibition of long-term potentiation in the CA1 region of mouse hippocampal slices. |
| TN7032 |
4'-O-Methylpyridoxine
|
4-methoxymethylpyridoxine,Ginkgotoxin |
Antioxidant
|
|
4'-O-Methylpyridoxine (MPN) is a vitamin-like compound discovered from Ginkgo biloba with antioxidant activity and cytotoxicity. |
| T4S21320 |
ISOGINKGETIN
|
4',4'''-Dimethylamentoflavone |
MMP
,
Others
|
|
1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti... |
| TN2125 |
Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside
|
Quercetin 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside |
Antioxidant
|
|
Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside) is a compound extracted from the leaves of Ginkgo biloba. Qu... |
| TN2462 |
Ginnol
|
Ginno |
Others
|
|
Ginno is a natural product Ginkgo biloba L. |
| TN1513 |
Clitorin
|
|
PKC
,
Antifection
|
|
Clitorin has free radical scavenging property. It shows significant interactions with CD38, it may have anti-hyperglycemic potential. |
| T83026 |
Antioxidant agent-18
|
|
|
|
Antioxidant Agent-18 (Compound 5), a flavonol glycoside derived from Ginkgo biloba, exhibits antioxidant properties through its ability to scavenge DPPH radicals (IC50: 15.8 μM) and reduce cytochrome c (IC50: 14.7 μM). |
| T79959 |
6-Hydroxykynurenic acid
|
6-HKA |
iGluR
|
|
6-Hydroxykynurenic acid (6-HKA), a kynurenic acid (KYNA) derivative isolated from Ginkgo leaves, functions as a low-affinity NMDAR antagonist with an IC50 of 59 μM [1]. |
| TN3594 |
Cardanol (C15:1)
|
|
Apoptosis
,
Others
|
|
Cardanol (C15:1), found in cashew nut shell liquid, induces mitochondria-associated apoptosis in human melanoma cells. |
| T4S2128 |
Bilobetin
|
|
PKA
,
PPAR
|
|
Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet. |
| T6389 |
Anacardic Acid
|
6-pentadecylsalicylic Acid,Hydroginkgolic acid |
Others
,
Epigenetic Reader Domain
,
Histone Acetyltransferase
,
Antibacterial
|
|
Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity, antibacterial activity, and inhibits prostagland... |
| T2836 |
Isorhamnetin
|
3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin |
MEK
,
PI3K
,
Endogenous Metabolite
|
|
Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LD... |
| T0887 |
D-Glucose
|
Dextrose,Glucopyranose,Grape sugar,D(+)-Glucose |
Endogenous Metabolite
|
|
D-Glucose (Glucopyranose) is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient... |
| TN1283 |
4'-O-Methylochnaflavone
|
|
Others
|
|
4'-O-Methylochnaflavone is a natural product |
| TN4865 |
Putraflavone
|
|
Beta Amyloid
,
BACE
|
|
Putraflavone possesses a good antioxidant activity via its DPPH free radical scavenging. |
