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ターゲット

阻害剤

天然化合物

1745

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T13112	Tat-NR2B9c	Tat-NR2Bct,NA-1	NO Synthase , iGluR
	Tat-NR2B9c (NA-1) is a postsynaptic density-95 (PSD-95) inhibitor with neuroprotective and antiepileptic effects.Tat-NR2B9c inhibits PSD-95d2, PSD-95d1, and PSD-95, which prevents the activation of NMDA-induced NADPH oxi...		NO Synthase , iGluR
T25245	CHM-1-P-Na
	CHM-1-P-Na is used as a hydrophilic prodrug of CHM-1.
T12181	NaV1.7 inhibitor-1		Sodium Channel
	NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).		Sodium Channel
T8555	Neuraminidase-IN-1	Novel NA Inhibitor,Compound Y-1	Others , Influenza Virus
	Neuraminidase-IN-1 (Compound Y-1) is a novel neuraminidase inhibitor.		Others , Influenza Virus
T3935	1-Naphthyl PP1	1-NA-PP 1	Src
	1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)		Src
T7371	1-Naphthyl PP1 hydrochloride	1-NA-PP 1 hydrochloride	Src
	1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-Src		Src
T13112L1	Tat-NR2B9c acetate	Tat-NR2B9c acetate (500992-11-0 Free base),NA-1 acetate	Others
	Tat-NR2B9c acetate (NA-1 acetate) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c acetate disrupts the PSD-...		Others
T12931	SLC13A5-IN-1		Stearoyl-CoA Desaturase (SCD)
			Stearoyl-CoA Desaturase (SCD)
T3459	VK3-OCH3	2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na	Others
	VK3-OCH3 (2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na) is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.		Others
T8579	Nav1.8-IN-1	5-(4-Chlorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]pyridine-3-carboxamide,CHEMBL1270208	Sodium Channel
	Nav1.8-IN-1 (CHEMBL1270208) is an inhibitor of human NaV1.8		Sodium Channel
T0386L	Ropivacaine	LEA-103 HCl	Potassium Channel , Sodium Channel
	Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.		Potassium Channel , Sodium Channel
T0386	Ropivacaine hydrochloride	Ropivacaine monohydrochloride	Potassium Channel , Sodium Channel
	Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity.		Potassium Channel , Sodium Channel
T3470	Cis-ACBD	cis-1-aminocyclobutane-1,3-dicarboxylic acid	Amino Acids and Derivatives
	Cis-ACBD (cis-1-aminocyclobutane-1,3-dicarboxylic acid) is a potent and selective N-methyl-D-aspartate receptor agonist.		Amino Acids and Derivatives
T13112L	Tat-NR2B9c TFA	NA-1 (TFA)	Others
	Tat-NR2B9c TFA is a 20-aa peptide, and acts as an inhibitor of postsynaptic density-95 (PSD-95)(EC50 of 6.7 nM for PSD-95d2), and possesses neuroprotective efficacy.		Others
T25953	PHPS1 Sodium	PHPS1 Na,PHPS1 Sodium salt
	PHPS1 sodium is a potent and selective inhibitor of Shp2, with Kis of 0.73, 5.8, 10.7, 5.8, and 0.47 μM for Shp2, Shp2-R362K, Shp1, PTP1B, and PTP1B-Q, respectively [1].
T6645	Ropivacaine hydrochloride monohydrate	Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,LEA-103 HCl	Potassium Channel , Sodium Channel
	Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.		Potassium Channel , Sodium Channel
T12219	NHE3-IN-1		Sodium Channel
	NHE3-IN-1 is a inhibitor of Na+/H+-exchanger 3 (NHE-3).		Sodium Channel
T5319	Rimeporide	EMD-87580	Sodium Channel
	Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.		Sodium Channel
T5333	Rimeporide hydrochloride	EMD-87580 hydrochloride	Sodium Channel
	Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.		Sodium Channel
T17243	VU0463271	N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide	Potassium Channel
	VU0463271 (N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide) is a potent and selective antagonist of the neuronal-specific potassium-chloride cotransporter 2 (KCC2), with an IC50 of 61 nM ...		Potassium Channel
T2238	Cariporide	HOE-642	Sodium Channel
	Cariporide (HOE-642) (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (...		Sodium Channel
T6641	Rilmenidine Phosphate		Apoptosis , Adrenergic Receptor , Autophagy , Imidazoline Receptor
	Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.
TP1033L	Transdermal Peptide Disulfide Acetate	TD 1 (peptide) acetate,Transdermal Peptide Disulfide Acetate (888486-23-5 free base)	ATPase
	Transdermal Peptide acetate(888486-23-5 free base) (TD 1 (peptide) acetate) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide...		ATPase
T36949	Niaprazine		5-HT Receptor , Adrenergic Receptor , Histamine Receptor
	Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low aff...		5-HT Receptor , Adrenergic Receptor , Histamine Receptor
T2238L	Cariporide Mesylate	Cariporide Mesylate salt,HOE-642,HOE 642,HOE642
	Cariporide Mesylate is a selective inhibitor of the Na+/H+ exchanger isoform 1.
T60652	NHE3-IN-2
	NHE3-IN-2 is an inhibitor of Na + /H + exchanger-3 (NHE3)[1].
T37473	SBFI AM	Sodium-binding Benzofuran Isophthalate Acetoxymethyl ester
	SBFI AM is a membrane-permeant, fluorescent Na+ indicator dye. It is selective for Na+ over K+ with Kd values of 20 and 120 mM for these ions, respectively. [1]Increasing concentration of Na+ increases the ratio of excit...
T80451	Ceratotoxin-2	CcoTx2,β-TRTX-cm1b	Sodium Channel
	Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel inhibitor, demonstrating half maximal inhibitory concentrations (IC50) of 8 nM for Na v 1.2/β 1 and 88 nM for Na v 1.3/β 1 [1].		Sodium Channel
T75280	Prilocaine acetate
	Prilocaine acetate, an amino amide compound, functions as a Na/K-ATPase inhibitor, exhibiting neurotoxic effects [1] [2].
T80039	ATX-II		Sodium Channel
	ATX-II, an Na+ channel modulator toxin derived from the sea anemone (Anemonia sulcata), causes delayed inactivation of the Na+ channels and has been linked to pulmonary vein arrhythmogenesis and atrial fibrillation [1] [...		Sodium Channel
T35923	Caloxin 2A1 TFA
	Caloxin 2A1 TFA is a peptide inhibitor specifically targeting the extracellular plasma membrane Ca2+-ATPase (PMCA), without influencing the basal activities of Mg2+-ATPase or Na+-K+-ATPase[1].
T78564	Depramine	GP 31406
	Depramine (GP 31406), a tricyclic antidepressant, exhibits pharmacological activity by inhibiting acetylcholinesterase, Mg^2+-ATPase, and Na^+/K^+ ATPase activity [1] [2].
T37707	14-Anhydrodigitoxigenin
	14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.1 It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 μM.2
T82936	ATX-II TFA		Sodium Channel
	ATX-II TFA, a specific Na+ channel modulator toxin, is derived from the venom of the sea anemone (Anemonia sulcata). This compound impedes the inactivation of Na+ channels and has been associated with arrhythmogenesis in...		Sodium Channel
T76374	SPAI-1
	SPAI-1, a peptide isolated from porcine duodenum, serves as a specific inhibitor to monovalent cation transporting ATPases, effectively inhibiting Na+, K+-ATPase and H+, K+-ATPase while stimulating Mg2+-ATPase in vitro [...
T80494	Tap1a	TRTX-Tap1a,Theraphotoxin-Tap1a,µ/ω-TRTX-Tap1a	Sodium Channel
	Theraphotoxin-Tap1a (Tap1a) is a spider venom-derived peptide that acts as an inhibitor of sodium channels, displaying IC50 values of 80 nM for Na v 1.7 and 301 nM for Na v 1.1. It demonstrates analgesic effects [1].		Sodium Channel
T75971	γ-1-Melanocyte Stimulating Hormone (MSH), amide
	γ-1-Melanocyte Stimulating Hormone (MSH), amide, a peptide consisting of 11 amino acids, plays a critical role in regulating sodium (Na+) balance and blood pressure by activating melanocortin receptor 3 (MC3-R).
T60469	Chloroprocaine
	Chloroprocaine (2-Chloroprocaine) is an effective Na,K-ATPase activity inhibitor with an IC 50 of 13 mM. Chloroprocaine is a local anesthetics that block peripheral nerve [1].
T37767	Transdermal Peptide Disulfide TFA
	Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA), an 11-amino acid peptide, specifically binds to the Na+/K+-ATPase beta-subunit (ATP1B1), predominantly interacting with its C-terminus. This compound is ca...
T61480	NHE3-IN-3
	NHE3-IN-3 (Compound 1) is a potent inhibitor of the isoform 3 of the Na+/H+ exchanger (NHE3). It exhibits pIC50 values of 6.2 and 6.6 against human and rat NHE3, respectively. Furthermore, NHE3-IN-3 showcases exceptional...
T75593	Parabuthus Granulatus Venom
	Parabuthus Granulatus Venom (Granulated Thick-tailed Venom), derived from the Granulated Thick-tailed scorpion, is notable for containing toxins that effectively inhibit voltage-gated Ca2+ and Na+ channels, demonstrating...
T80178	Dc1a		Sodium Channel
	Dc1a, a toxin isolated from the desert bush spider Diguetia canities [1], potently facilitates the opening of the German cockroach Na v channel (BgNa v 1).		Sodium Channel
T80454	BmK-M1		Sodium Channel
	BmK-M1, a scorpion-derived toxin, consists of a 64-amino acid polypeptide stabilized by four disulfide bridges. This compound functions as an inhibitor of the Na+ channel, classifying it as both a cardiotoxin and a neuro...		Sodium Channel
T75360	Oxonol VI
	Oxonol VI serves as an optical indicator for membrane potentials within lipid vesicles and is effective in identifying variations in membrane potential linked to the activity of the (Na + + K +)-ATPase in reconstituted v...
TP1268	CEF19, Epstein-Barr Virus latent NA-3A (458-466)	CEF19,Epstein-Barr Virus latent NA-3A 458-466
	CEF19, Epstein-Barr Virus latent NA-3A (458-466) is a single peptide epitope, YPLHEQHGM, representing residues 458-466 of the type 1 Epstein-Barr Virus (EBV) nuclear antigen 3A protein (B95.8 strain).
T37766	Transdermal Peptide (TD 1 (peptide))
	Transdermal Peptide is a 11-amino acid peptide, binds to Na+/K+-ATPase beta-subunit (ATP1B1), and enhances the transdermal delivery of many macromolecules. Transdermal Peptide (TD1) binds to ATP1B1, and mainly interacts ...
T73083	Nipradolol	KT 210 ; K 351 ; Hypadil,Hypadil,KT 210,K 351
	Nipradolol (KT-210; K-351), an alpha-1-adrenergic receptor antagonist, effectively inhibits the elevation of intraocular pressure (IOP) induced by Phenylephrine in an albino rabbit model and suppresses noradrenaline (NA)...
T75594	Harpactira Baviana Venom
	Harpactira Baviana Venom (Baboon Tarantula Venom), derived from the king baboon spider, modulates Na V 1.8 and induces hyperalgesia [1] [2].
T60939	Neuraminidase-IN-6
	Neuraminidase-IN-6 (Compound 5c) is a derivative of 1,3,4-triazole-3-acetamide. Neuraminidase-IN-6 is a potent neuraminidase inhibitor with an IC50 value of 0.11 μM. Neuraminidase (NA) is an ideal target for the anti-inf...
T80176	Crotamine		Sodium Channel
	Crotamine, a 42 amino acid toxin featuring three disulfide bridges, functions as a Na+ channel modulator with analgesic properties. This compound interacts with lipid membranes and exhibits myonecrotic activity, and can ...		Sodium Channel

Compounds

Tat-NR2B9c

T13112

Synonym: Tat-NR2Bct,NA-1

Target: NO Synthase, iGluR

Target: Sodium Channel

Neuraminidase-IN-1

T8555

Synonym: Novel NA Inhibitor,Compound Y-1

Target: Others, Influenza Virus

1-Naphthyl PP1 hydrochloride

T7371

Synonym: 1-NA-PP 1 hydrochloride

Target: Src

Tat-NR2B9c acetate

T13112L1

Synonym: Tat-NR2B9c acetate (500992-11-0 Free base),NA-1 acetate

Target: Stearoyl-CoA Desaturase (SCD)

VK3-OCH3

T3459

Synonym: 2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na

Target: Others

Nav1.8-IN-1

T8579

Synonym: 5-(4-Chlorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]pyridine-3-carboxamide,CHEMBL1270208

Target: Sodium Channel

Ropivacaine

T0386L

Synonym: LEA-103 HCl

Target: Potassium Channel, Sodium Channel

Ropivacaine hydrochloride

T0386

Synonym: Ropivacaine monohydrochloride

Target: Potassium Channel, Sodium Channel

Cis-ACBD

T3470

Synonym: cis-1-aminocyclobutane-1,3-dicarboxylic acid

Target: Amino Acids and Derivatives

Synonym: PHPS1 Na,PHPS1 Sodium salt

Target:

Ropivacaine hydrochloride monohydrate

T6645

Synonym: Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,LEA-103 HCl

Target: Potassium Channel, Sodium Channel

NHE3-IN-1

T12219

Synonym:

Target: Sodium Channel

Rimeporide

T5319

Synonym: EMD-87580

Target: Sodium Channel

Rimeporide hydrochloride

T5333

Synonym: EMD-87580 hydrochloride

Target: Sodium Channel

VU0463271

T17243

Synonym: N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide

Target: Potassium Channel

Cariporide

T2238

Synonym: HOE-642

Target: Sodium Channel

Rilmenidine Phosphate

T6641

Synonym:

Target: Apoptosis, Adrenergic Receptor, Autophagy, Imidazoline Receptor

Transdermal Peptide Disulfide Acetate

TP1033L

Synonym: TD 1 (peptide) acetate,Transdermal Peptide Disulfide Acetate (888486-23-5 free base)

Target: 5-HT Receptor, Adrenergic Receptor, Histamine Receptor

Cariporide Mesylate

T2238L

Synonym: Cariporide Mesylate salt,HOE-642,HOE 642,HOE642

Synonym: Sodium-binding Benzofuran Isophthalate Acetoxymethyl ester

Target:

Ceratotoxin-2

T80451

Synonym: CcoTx2,β-TRTX-cm1b

Target: Sodium Channel

Target: Sodium Channel

14-Anhydrodigitoxigenin

Target: Sodium Channel

Synonym: TRTX-Tap1a,Theraphotoxin-Tap1a,µ/ω-TRTX-Tap1a

Target: Sodium Channel

γ-1-Melanocyte Stimulating Hormone (MSH), amide

Transdermal Peptide Disulfide TFA

Parabuthus Granulatus Venom

Target: Sodium Channel

BmK-M1

T80454

Synonym:

Target: Sodium Channel

CEF19, Epstein-Barr Virus latent NA-3A (458-466)

TP1268

Synonym: CEF19,Epstein-Barr Virus latent NA-3A 458-466

Target:

Transdermal Peptide (TD 1 (peptide))

Synonym: KT 210 ; K 351 ; Hypadil,Hypadil,KT 210,K 351

Target:

Harpactira Baviana Venom

Target: Sodium Channel

カタログ番号	製品名	別名	ターゲット
TN6713	6-Benzoylheteratisine	Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth	Sodium Channel
	6-Benzoylheteratisine (Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth) is a Aconitum alkaloid. It can inhibits voltage-gated Na+ channels in rat brain synaptosomes		Sodium Channel
T6856	Halofuginone	Tempostatin,empostatin,RU-19110	Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
	Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
T29078	Ursodeoxycholic acid sodium	UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium	FXR , Endogenous Metabolite , GPCR19
	Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it...		FXR , Endogenous Metabolite , GPCR19
T3524	Halofuginone hydrobromide	Tempostatin,RU-19110 (hydrobromide),Stenorol	Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
	Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
T2822	Ginsenoside Rb1	Gypenoside Ⅲ,Gypenoside III	ATPase , Mitophagy , IRAK , NF-κB , Autophagy , HSV
	Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.		ATPase , Mitophagy , IRAK , NF-κB , Autophagy , HSV
TN5073	Strophanthidin	Strophanthidine	ATPase , Calcium Channel
	Strophanthidin (Strophanthidine) can induce calcium overload in vivo.		ATPase , Calcium Channel
TCA2511	11Beta-hydroxyprogesterone		Sodium Channel
	The progesterone derivatives 11 alpha- and 11 beta-hydroxyprogesterone are potent inhibitors of 11 beta-hydroxysteroid dehydrogenase (isoforms 1 and 2) in vitro and can confer mineralocorticoid activity on corticosterone...		Sodium Channel
T5S0890	Oleandrin	Neriostene,Folinerin,Foliandrin	Apoptosis , ATPase , Potassium Channel , Sodium Channel
	1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, ...		Apoptosis , ATPase , Potassium Channel , Sodium Channel
T1719	Bufalin		ATPase
	Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potenti...		ATPase
T4973	Paraxanthine	1,7-DIMETHYLXANTHINE	Endogenous Metabolite
	Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is struc...		Endogenous Metabolite
TJP2872	Acevaltrate	Acevaltratum,Acetoxyvaltrate	ATPase , Others
	1. Acevaltrate (Acevaltratum) displays high cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and against COLO 320, a human colorectal cancer cell line, with IC50 values of 1-6 uM.		ATPase , Others
T5S1982	Periplocin	Periplocoside	Apoptosis , Others
	1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato...		Apoptosis , Others
T72429	α-Lipoic Acid sodium	Thioctic acid sodium,DL-α-Lipoic acid sodium,Thioctic acid sodium ; (±)-α-Lipoic acid sodium ; DL-α-Lipoic acid sodium,(±)-α-Lipoic acid sodium
	α-Lipoic Acid (Thioctic acid) sodium, an essential cofactor for mitochondrial enzyme complexes, serves as an antioxidant. It suppresses NF-κB-dependent activation of HIV-1 LTR [1] [2] [3] and triggers ER (endoplasmic ret...
TN4108	Ganoderic acid Z		Antifection
	The binding affinities of ganoderic acid DM and ganoderic acid Z (ÎGbind, -16.83 and-10.99 kcal mol-1) are comparable to that of current commercial drug oseltamivir (-23.62 kcal mol-1);Ganoderic acid DM is a potential s...		Antifection
T82764	Cd1a	β-TRTX-cd1a,β-Theraphotoxin-cd1a
	Cd1a, a β-toxin from the African spider Ceratogyrus darlingi, modulates calcium ion channels and inhibits human calcium ion channels (Ca v 2.2)(IC 50 2.6 μM) as well as mouse sodium ion channels (Na v 1.7). This compound...
T38069	Aquastatin A
	Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC...
T35779	Oosporein
	Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectiv...

天然物製品

6-Benzoylheteratisine

TN6713

Synonym: Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth

Target: Sodium Channel

Halofuginone

T6856

Synonym: Tempostatin,empostatin,RU-19110

Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Ursodeoxycholic acid sodium

T29078

Synonym: UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium

Target: FXR, Endogenous Metabolite, GPCR19

Halofuginone hydrobromide

T3524

Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol

Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Ginsenoside Rb1

T2822

Synonym: Gypenoside Ⅲ,Gypenoside III

Target: ATPase, Mitophagy, IRAK, NF-κB, Autophagy, HSV

Strophanthidin

TN5073

Synonym: Strophanthidine

Target: ATPase, Calcium Channel

11Beta-hydroxyprogesterone

TCA2511

Synonym:

Target: Sodium Channel

Oleandrin

T5S0890

Synonym: Neriostene,Folinerin,Foliandrin

Target: Apoptosis, ATPase, Potassium Channel, Sodium Channel

Synonym: 1,7-DIMETHYLXANTHINE

Target: Endogenous Metabolite

Acevaltrate

TJP2872

Synonym: Acevaltratum,Acetoxyvaltrate

Target: ATPase, Others

Periplocin

T5S1982

Synonym: Periplocoside

Target: Apoptosis, Others

α-Lipoic Acid sodium

T72429

Synonym: Thioctic acid sodium,DL-α-Lipoic acid sodium,Thioctic acid sodium ; (±)-α-Lipoic acid sodium ; DL-α-Lipoic acid sodium,(±)-α-Lipoic acid sodium

Synonym: β-TRTX-cd1a,β-Theraphotoxin-cd1a

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03845	Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein (His)	H7N9	HEK293 Cells
	Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.6 kDa.
TMPY-03788	ATP1B1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ATP1B1 belongs to the family of Na+/K+and H+/K+-ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. ATP1B1 is a subunit of Na+/K+-ATPase. Na+/K+-ATPase is an integral membrane protein responsible for es...
TMPY-00143	Influenza A H5N1 (A/Thailand/1(KAN-1)/2004) Neuraminidase/NA Protein (His), Biotinylated	H5N1	HEK293 Cells
	Influenza A H5N1 (A/Thailand/1(KAN-1)/2004) Neuraminidase/NA Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.6 kDa.
TMPY-04532	Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein	H7N9	HEK293 Cells
	Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells.
TMPY-01393	Influenza A H5N1 (A/Anhui/1/2005) Neuraminidase/NA Protein	H5N1	HEK293 Cells
	Influenza A H5N1 (A/Anhui/1/2005) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 49.2 kDa and the accession number is A7Y9K2.
TMPY-03843	Influenza A H7N9 (A/Shanghai/1/2013) Neuraminidase/NA Protein	H7N9	HEK293 Cells
	Influenza A H7N9 (A/Shanghai/1/2013) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells.
TMPY-00495	Influenza A H5N1 (A/Thailand/1(KAN-1)/2004) Neuraminidase/NA Protein (His)	H5N1	HEK293 Cells
	Influenza A H5N1 (A/Thailand/1(KAN-1)/2004) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.6 kDa.
TMPY-03846	Influenza A H7N9 (A/Shanghai/1/2013) Neuraminidase/NA Protein (His)	H7N9	HEK293 Cells
	Influenza A H7N9 (A/Shanghai/1/2013) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.6 kDa.
TMPY-05502	Influenza A H5N1 (A/Anhui/1/2005) Neuraminidase/NA Protein (His)	H5N1	Baculovirus Insect Cells
	Influenza A H5N1 (A/Anhui/1/2005) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51.1 kDa and the accession number is A7Y9K2.
TMPY-02427	Influenza A H5N1 (A/Hubei/1/2010) Neuraminidase/NA Protein (His)	H5N1	HEK293 Cells
	Influenza A H5N1 (A/Hubei/1/2010) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.9 kDa and the accession number is G2U0U0.
TMPY-05757	Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein (His), Biotinylated	H7N9	HEK293 Cells
	Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.6 kDa.
TMPH-02119	SLC5A2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1.; Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affini...
TMPY-04460	OXSR1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins. OXSR1 regulates downstream kinases in response to environme...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&...
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-04069	Neurotrophin 3 Protein, Human, Recombinant	Human	E. coli
	NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely relate...
TMPY-03958	TGF alpha Protein, Human, Recombinant	Human	E. coli
	The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared...
TMPK-00305	TGFBR1 Protein, Human, Recombinant (mFc & Avi)	Human	HEK293 Cells
	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPK-00114	C-Reactive Protein /CRP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPK-00383	ACE2/ACEH Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio...
TMPY-02031	B7-H3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	B7-H3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1.
TMPY-00699	CD155/PVR Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD155/PVR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P15151-1.
TMPY-00586	CLEC-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CLEC-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9JL99-1.
TMPY-00972	FGFR2 Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the accession number is P21802-1.
TMPY-03762	E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.1 kDa and the accession number is P12830-1.
TMPK-01074	CD163 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ...
TMPY-00915	Serpin A1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is P01009-1.
TMPY-02794	TLR2 Protein, Human, Recombinant (aa 1-587, His)	Human	Baculovirus Insect Cells
	TLR2 Protein, Human, Recombinant (aa 1-587, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 65.5 kDa and the accession number is O60603-1.
TMPK-00176	BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (...
TMPY-05016	HHLA2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	HHLA2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.4 kDa and the accession number is Q9UM44-1.
TMPY-04925	CD8 beta Protein, Human, Recombinant, Biotinylated	Human	HEK293 Cells
	CD8 beta Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1.
TMPY-04957	PD-L2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-00654	ACVR2B Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ACVR2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.0 kDa and the accession number is Q13705-1.
TMPY-03481	IL-1R2 Protein, Human, Recombinant	Human	HEK293 Cells
	IL-1R2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.4 kDa and the accession number is P27930-1.
TMPY-03363	C-Reactive Protein Protein, Human, Recombinant	Human	HEK293 Cells
	C-Reactive Protein Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1.
TMPY-03383	IL-7 Protein, Human, Recombinant	Human	E. coli
	IL-7 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P13232-1.
TMPK-01151	MXRA8 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses. MXRA8 Protein, Human, Recombinant (His) is expressed in ...
TMPY-01065	GM-CSFR alpha Protein, Human, Recombinant (His)	Human	HEK293 Cells
	GM-CSFR alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P15509-1.
TMPY-04966	PCSK9 Protein, Human, Recombinant (D374Y, His)	Human	HEK293 Cells
	PCSK9 Protein, Human, Recombinant (D374Y, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.5 kDa and the accession number is Q8NBP7-1.
TMPY-04970	TIGIT Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-05435	ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is Q15389-1.
TMPY-01037	CSF1R Protein (Met1-Glu512), Human, Recombinant (His)	Human	HEK293 Cells
	CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56 kDa and the accession number is P07333-1.
TMPY-03947	CD48 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD48 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is P09326-1.
TMPY-01166	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P20333-1.
TMPY-01853	SIRP gamma Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SIRP gamma Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is Q9P1W8-1.
TMPY-00399	HER3/ERBB3 Protein, Human, Recombinant	Human	HEK293 Cells
	HER3/ERBB3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.3 kDa and the accession number is P21860-1.
TMPY-01283	Glypican 3/GPC3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Glypican 3/GPC3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62 kDa and the accession number is P51654-1.
TMPY-06077	LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.3 kDa and the accession number is O75019-1.
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