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Search Results for " albicans "

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114

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45

天然化合物

9

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T8536 Filastatin Antifungal
Filastatin is a long-lasting inhibitor of Candida albicans filamentation, and has potent antifungal effect.
T38240 2,6-Dichlorodiphenylamine Antibacterial
2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1...
T27617 Inz-1 P450
Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human. Inz-1 reverses Fluconazole or other triazole antifungals’ resistance in the path...
T21678 3MB-PP1 PLK
3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting Plk1. 3MB-PP1 specifi...
T19717 Cyclo-L-Trp-L-Trp Antifungal
Cyclo-L-Trp-L-Trp is a broad-spectrum antifungal. It also induces a high degree of acetylation of histones.
T17022 Tebuconazole P450 , Antifungal
Tebuconazole is an agricultural azole fungicide. It can also inhibit CYP51 (IC50s: 0.9 and 1.3 μM for Candida albicans CYP51 and truncated Homo sapiens CYP51, respectively).
T22387 NSC 55655 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione Others
NSC 55655 (5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione) possesses antimicrobial and antioxidant activities and inhibits the proliferation of B. subtilis, S. aureus, K. pneumonia, E. coli, S. typhi , A. niger and C...
T9602 Monocaprin Anti-infection , Antibacterial
Monocaprin is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans.
T16412 Oteseconazole VT-1161 P450 , Antifungal
Oteseconazole (VT-1161) is an orally active anti-fungal agent. Oteseconazole displays no obvious effect on human CYP51. It also potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM).
T38137 3,5-Dimethylbenzaldehyde Endogenous Metabolite , Antifungal
3,5-Dimethylbenzaldehyde has broad-spectrum antimicrobial activity, inhibiting Bacillus subtilis, Pseudomonas albicans, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae.
T77686 1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone Antifungal
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone has broad-spectrum antifungal activity with inhibitory effects on Candida albicans, Aspergillus niger, Pseudomonas aeruginosa and Staphylococcus aureus.
T2305 Isavuconazole BAL-4815,RO-0094815 P450 , Antibiotic , Antifungal
Isavuconazole (RO-0094815)(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557 with MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabr...
T77608 1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl- Antifungal
1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl- can be used as a broad-spectrum antimicrobial agent with inhibitory activity against Aspergillus niger Bacillus subtilis, Pseudomonas albicans, Escherichia coli and Staph...
T4040 AN2718 Antifungal
AN2718 inhibits protein synthesis through the OBORT mechanism and displays broad antifungal effectiveness.
T13787 N-563 Others
N-563 promotes resistance to Candida albicans infection in mice
T35297 ZD 0870 D 0870,D0870,ZD0870
ZD 0870, used to treat infections caused by fluconazole-resistant candida albicans.
T28596 RO-09-4609 RO 09-4609,RO09-4609,RO 094609,RO-094609
RO-09-4609 is a potent and selective inhibitor of Candida albicans N-myristoyltransferase (CaNmt).
T10311 Amphotericin X1 Others
Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (...
T61502 Antifungal agent 32
Antifungal agent 32 (compound 1a) is a highly effective antifungal compound. It displays strong inhibitory activity against Candida albicans filamentation and biofilm formation, as well as inhibiting the morphological sw...
T71939 PS77
PS77 is a Pkh inhibitor directed to the PIF-pocket with increased selectivity for C. albicans Pkh2.
T80629 2-Dodecanol
2-Dodecanol suppresses both hyphal development and SIR2 gene expression in Candida albicans [1].
T81494 PhD3
PhD3, an antimicrobial peptide originating from monkey leukocytes, exhibits potent activity against various bacteria and the fungus Candida albicans [1].
T63802 Antifungal agent 35
Antifungal agent 35 is an effective antifungal agent that potentiates the antifungal activity of fluconazole against C. albicans.
T81493 PhD4
PhD4, an antimicrobial peptide originating from monkey leukocytes (white blood cells), exhibits efficacy against both bacteria and the fungus Candida albicans [1].
T81496 PhD1
PhD1, an antimicrobial peptide originating from monkey leukocytes, exhibits efficacy against various bacteria and the fungus Candida albicans [1].
T80293 RP-1
RP-1, an antimicrobial peptide, exhibits activity against a range of pathogens, including S. aureus, S. typhimurium, E. coli, and C. albicans [1].
T81495 PhD2
PhD2, an antimicrobial peptide originating from monkey leukocytes, exhibits efficacy against bacteria and the fungus Candida albicans [1].
T76264 Nisin Z
Nisin Z, an antimicrobial and anti-inflammatory peptide, demonstrates efficacy against Gram-positive bacteria and fungi, including C. albicans [1] [4].
T25342 Discobahamin A
Discobahamin A is a bioactive peptide isolated from a new species of the Bahamian deep water marine sponge Discodermia. It is a growth of Candida albicans inhibitor.
T25343 Discobahamin B
Discobahamin B is a bioactive peptide isolated from a new species of the Bahamian deep water marine sponge Discodermia. It is a growth of Candida albicans inhibitor.
T74273 Antifungal agent 52
Antifungal agent 52 (compound 6c), a tetrazole derivative, inhibits ergosterol synthesis and significantly exhibits antifungal activity against Candida albicans by affecting the permeabilization of the C. albicans sessil...
T64235 Antifungal agent 25
Antifungal agent 25 is an effective, broad-spectrum, metabolically stable antifungal agent in vivo. antifungal agent 25 exhibits antifungal effects against both Candida albicans and fluconazole-resistant Candida albicans...
T36533 SCH 725674
SCH 725674 is an antifungal macrolide originally isolated from Aspergillus. It inhibits the growth of S. cerevisiae and C. albicans in vitro (MICs = 8 and 32 μg/ml, respectively).
T35700 FR901379
FR901379 is an echinocandin-like antifungal lipopeptide.1 It is active against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml). FR901379 is protective against...
T74272 Antifungal agent 84
Antibacterial Agent 84, an antifungal compound, effectively inhibits candidiasis through a CNB1-dependent mechanism and reduces the viability of the C. albicans biofilm [1].
T36434 Sordarin sodium
Sordarin is an inhibitor of fungal protein synthesis originally isolated from S. araneosa.[1] It binds to elongation factor 2 (EF-2) in the presence of ribosomes and inhibits the uncoupled GTPase activity of equimolar mi...
T69051 Aculeacin A
Aculeacin A is used to study mutations that lead to antibiotic resistance in Saccharomyces cerevisiae, the inhibition of Candida albicans and the morphogenetic transformation of Candida albicans when treated. Aculeacin A...
T62098 Antifungal agent 28
Antifungal agent 28 (compound 18) is a selective and potent antifungal agent that disrupts mature Candida biofilms and inhibits pathogenic strains of Candida albicans and non-Candida albicans, including fluconazole-resis...
T83715 Histatin 3 TFA Hst-3
Histatin 3, a salivary antimicrobial peptide, exhibits activity against C. albicans with an LC50 of 9.2 µM. Additionally, at a concentration of 12 µM, it promotes actin polymerization in cell-free assays.
T80407 Peptide 5g
Peptide 5g, an antimicrobial peptide, inhibits E. coli, S. aureus, and C. albicans, exhibiting minimum inhibitory concentration (MIC) values of 30, 10, and 12.5 μg/mL, respectively [1].
T80932 Tritrpticin
Tritrpticin, an antimicrobial peptide originating from pig bone marrow, exhibits effectiveness against Aspergillus fumigatus and Candida albicans, with minimum inhibitory concentrations (MIC) of 250 and 1000 μg/ml, respe...
T62159 Antifungal agent 24
Antifungal agent 24 (Compound 6) is an antifungal agent that inhibits Candida albicans (MIC: 0.03 μg/ml).
T76470 GVLSNVIGYLKKLGTGALNAVLKQ
GVLSNVIGYLKKLGTGALNAVLKQ (PGQ) is a 24-amino acid antimicrobial peptide capable of forming an α-helix structure. It exhibits activity against both Gram-negative and Gram-positive bacteria, as well as the yeast Candida al...
TP1518 Lactoferrin (17-41) Lactoferrin 17-41
Lactoferrin (17-41) is amino acids 17 to 41 fragment of lactoferrin, known as lactoferricin B. Lactoferrin (17-41) shows anti-fungal properties in combination of other anti-fungal agents.Candida Albicans is one of the ta...
T63064 Antibacterial agent 100
Antibacterial agent 100 (Compound 7c) is an antibacterial and fungal agent that acts on Staphylococcus aureus (MIC: 4 μg/mL), Candida albicans (MIC: 4 μg/mL) and Cryptococcus neoformans (MIC: 4 μg/mL). neoformans (MIC: 8...
T61308 Antifungal agent 27
Antifungal agent 27 (compound 7) is a chemical compound possessing antifungal properties. It exhibits moderate antibacterial activity and weak antifungal activity against MRSA and C. albicans SS5314, with minimal inhibit...
T61398 Chitin synthase inhibitor 3
Chitin Synthase Inhibitor 3 (Compound 2d) is a potent inhibitor of chitin synthase, exhibiting an IC50 value of 0.16 mM and demonstrating antifungal activity with a minimum inhibitory concentration (MIC) of 1 μg/mL again...
T80365 Maximin H39
Maximin H39, an antimicrobial peptide, exhibits antibacterial activity against C. albicans, S. aureus, and B. subtilis with minimum inhibitory concentrations (MIC) of 9.4, 9.4, and 18.8 μg/mL, respectively. It also demon...
T80400 Peptide 5e
Peptide 5e, an antimicrobial peptide, exhibits inhibitory activity against E. coli, S. aureus, and C. albicans with respective minimum inhibitory concentration (MIC) values of 30, 5, and 25 μg/mL [1].
T80296 SP-B peptide
SP-B peptide is an antimicrobial agent with antifungal activity demonstrated against Cryptococcus neoformans, Candida albicans, and Aspergillus fumigatus strains[1].

Compounds

Filastatin
T8536
Synonym:
Target: Antifungal
2,6-Dichlorodiphenylamine
T38240
Synonym:
Target: Antibacterial
Inz-1
T27617
Synonym:
Target: P450
3MB-PP1
T21678
Synonym:
Target: PLK
Cyclo-L-Trp-L-Trp
T19717
Synonym:
Target: Antifungal
Tebuconazole
T17022
Synonym:
Target: P450, Antifungal
NSC 55655
T22387
Synonym: 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione
Target: Others
Monocaprin
T9602
Synonym:
Target: Anti-infection, Antibacterial
Oteseconazole
T16412
Synonym: VT-1161
Target: P450, Antifungal
3,5-Dimethylbenzaldehyde
T38137
Synonym:
Target: Endogenous Metabolite, Antifungal
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone
T77686
Synonym:
Target: Antifungal
Isavuconazole
T2305
Synonym: BAL-4815,RO-0094815
Target: P450, Antibiotic, Antifungal
1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl-
T77608
Synonym:
Target: Antifungal
AN2718
T4040
Synonym:
Target: Antifungal
N-563
T13787
Synonym:
Target: Others
ZD 0870
T35297
Synonym: D 0870,D0870,ZD0870
Target:
RO-09-4609
T28596
Synonym: RO 09-4609,RO09-4609,RO 094609,RO-094609
Target:
Amphotericin X1
T10311
Synonym:
Target: Others
Antifungal agent 32
T61502
Synonym:
Target:
PS77
T71939
Synonym:
Target:
2-Dodecanol
T80629
Synonym:
Target:
PhD3
T81494
Synonym:
Target:
Antifungal agent 35
T63802
Synonym:
Target:
PhD4
T81493
Synonym:
Target:
PhD1
T81496
Synonym:
Target:
RP-1
T80293
Synonym:
Target:
PhD2
T81495
Synonym:
Target:
Nisin Z
T76264
Synonym:
Target:
Discobahamin A
T25342
Synonym:
Target:
Discobahamin B
T25343
Synonym:
Target:
Antifungal agent 52
T74273
Synonym:
Target:
Antifungal agent 25
T64235
Synonym:
Target:
SCH 725674
T36533
Synonym:
Target:
FR901379
T35700
Synonym:
Target:
Antifungal agent 84
T74272
Synonym:
Target:
Sordarin sodium
T36434
Synonym:
Target:
Aculeacin A
T69051
Synonym:
Target:
Antifungal agent 28
T62098
Synonym:
Target:
Histatin 3 TFA
T83715
Synonym: Hst-3
Target:
Peptide 5g
T80407
Synonym:
Target:
Tritrpticin
T80932
Synonym:
Target:
Antifungal agent 24
T62159
Synonym:
Target:
GVLSNVIGYLKKLGTGALNAVLKQ
T76470
Synonym:
Target:
Lactoferrin (17-41)
TP1518
Synonym: Lactoferrin 17-41
Target:
Antibacterial agent 100
T63064
Synonym:
Target:
Antifungal agent 27
T61308
Synonym:
Target:
Chitin synthase inhibitor 3
T61398
Synonym:
Target:
Maximin H39
T80365
Synonym:
Target:
Peptide 5e
T80400
Synonym:
Target:
SP-B peptide
T80296
Synonym:
Target:
1 2 3
カタログ番号 製品名 別名 ターゲット
T1388 Fluconazole UK-49858 Antibiotic , Antifection , Antifungal
Fluconazole (UK-49858) is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.
T14046 Anandamide (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide Cannabinoid Receptor , Endogenous Metabolite
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy...
T7029 Pseudolaric Acid C Antifungal
Pseudolaric Acid C has weak antifungal activity against Candida albicans.
T37267 Pachybasin Antibacterial
Pachybasin is an anthraquinone fungal metabolite. Pachybasin shows antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and...
TN1877 Lonicerin Apoptosis , Antibacterial
Lonicerin has antioxidant, anti-arthritic and antifungal activities, it can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
T5S0636 Citric acid Citro,Citretten Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic
1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili...
T1678 Nystatin Stamycin,Fungicidin,Nystavescent Apoptosis , Antibiotic , Antifungal
Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat skin and oropharyngeal candidiasis.
TN7224 2,2'-Dihydroxy chalcone Antibacterial , Autophagy
2,2'-Dihydroxy chalcone is a potent inhibitor of β-glucuronidase (IC50=1.6±0.2 μM) and lysozyme (IC50=1.4±0.2 μM) release from rat neutrophils stimulated with fMLP/CB.2,2'-Dihydroxy chalcone has inhibitory activity again...
T4S1321 (+)-Magnoflorine chloride Magnoflorine chloride,Corytuberine methochloride,Thalictrine chloride,Escholine chloride Others , Antifungal
(+)-Magnoflorine chloride (Escholine chloride) has anti-inflammatory activity, it can inhibit inflammations.
T3S1320 (+)-Magnoflorine iodide Magnoflorine iodide,Thalictrine iodide,Corytuberine Methiodide Others , Antifungal
(+)-Magnoflorine iodide (Thalictrine iodide) has anti-inflammatory activity, it can inhibit inflammations.
T0011 2-Phenylethanol Phenethyl alcohol,2-Phenylethyl alcohol,Benzyl carbinol,Phenylethanol,Benzeneethanol Others , Virus Protease , Antibacterial , Antibiotic
2-Phenylethanol (Phenylethanol) is an antimicrobial, antiseptic, and disinfectant. It is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
T3S1319 (+)-Magnoflorine Escholin,Magnoflorine,Thalictrin,Escholine Others , Antifungal
(+)-Magnoflorine (Thalictrin) has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. Magnoflorine and Sinomenine have protective effects, are mediated by some mech...
T25718 Lichesterol
Lichesterol is extracted from polyene antibiotic-resistant Candida albicans.
T79931 Mutanocyclin
Mutanocyclin, a powerful antifungal agent, inhibits the filamentation of Candida albicans (C. albicans) and decreases the mRNA expression of HWP1, ECE1, FLO8, TEC1. Furthermore, it suppresses the yeast-form in ex vivo mo...
T11895 Luteolin-7-rutinoside Others
T70891 Pyridoxatin
Pyridoxatin is a fungal metabolite that inhibits production of thiobarbituric acid reactive substance (TBARS). Pyridoxatin inhibits hemolysis induced by the free radical generator AAPH and is active against C. albicans.
TN1561 Dehydroglaucine Antifection
Dehydroglaucine is an acetylcholinesterase inhibitor, it shows antimicrobial activity against Staphylococcus aureus, Mycobacterium smegmatis, Candida albicans, and Aspergillus niger.
T28379 PF-1163B PF1163B,(-)-PF1163B,PF 1163B
PF-1163B is an antifungal agent form Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis with IC50 value of 34 ng/ml. PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candid...
TN2032 Pachypodol Antifection
Pachypodol has antibacterial and antifungal activities against Bacillus subtilis, Staphylococcus aureus, Staphylococcus faecalis, Echerichia coli, Pseudomonas aeruginosa, Candida albicans, Candida krusei and Candida gala...
TN3978 Epitaraxerol Antifection
Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes, A. niger, S. aureus, E. coli, P. aeruginosa, and B. subtilis.
TN2492 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone Others
1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone has moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines, but lacks antifungal activity against Candida albicans.
TN3400 Altechromone A Antifection
Altechromone A has antimicrobial activity, it is active against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively.
T37712 Fumiquinazoline D
Fumiquinazoline D is a fungal metabolite originally isolated from A. fumigatus that has activity against Gram-positive and Gram-negative bacteria (MICs = 8-16 μg/ml) as well as F. solani and C. albicans fungi (MICs = 32 ...
TN3709 Coronarin D ethyl ether NF-κB
Coronarin D inhibits NF-KB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis.It shows promising antifungal activity against C. albicans ...
T37444 Aranorosin
Aranorosin is a fungal metabolite originally isolated from P. roseus. It has antimicrobial activity against B. subtilis, A. niger, and C. albicans when used at a concentration of 1 mg/ml. Aranorosin also reduces viabilit...
T80335 Maximin H3
Maximin H3, an antimicrobial peptide from Chinese red belly toad Bombina maxima skin secretions, exhibits antimicrobial properties against Escherichia coli ATCC25922, Staphylococcus aureus ATCC2592, Bacillus pyocyaneus C...
TN3723 Cryptomeridiol PAFR , Antifection
Cryptomeridiol is a potential skin-whitening agent, exhibits melanogenesis inhibitory activity on α-MSH-stimulated B16 melanoma cells. Cryptomeridiol has low activity against A. niger, T. mentagrophytes, and C. albicans....
T38016 Hirsutide
Hirsutide is a cyclotetrapeptide fungal metabolite produced by the entomopathogenic fungus Hirsutella. It has antibacterial activity against C. pyogenes, S. aureus, P. aeruginosa, and K. pneumonia (MICs = 25, 13, 6, and ...
T80332 Maximin H1
Maximin H1, an antimicrobial peptide sourced from the skin secretions of the Chinese red belly toad (Bombina maxima), exhibits efficacy against several pathogens, including Escherichia coli (ATCC25922), Staphylococcus au...
T80334 Maximin H2
Maximin H2, an antimicrobial peptide originating from the skin secretions of the Chinese red belly toad (Bombina maxima), exhibits inhibitory effects on a range of microorganisms, specifically Escherichia coli (ATCC25922...
TN1651 Furanodiene Apoptosis , PARP , Reactive Oxygen Species , Caspase , CDK , P-gp
Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
T80349 Maximin H4
Maximin H4, an antimicrobial peptide originating from the skin secretions of the Chinese red belly toad (Bombina maxima), exhibits inhibitory activity against a spectrum of microorganisms, including Escherichia coli (ATC...
T69225 Verrucarin J Muconomycin B
Verrucarin J (Muconomycin B), derived from the Myrothecium fungus family, effectively generates reactive oxygen species (ROS) to induce apoptosis in various cancer cell lines, including A549, HCT 116, and SW-620. Besides...
T36403 Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate
Preterramide C is a fungal metabolite that has been found inA. terreus.1It is active againstS. aureus(MIC = 52.4 μM) but notE. aerogenes,P. aeruginosa, orC. albicans(MICs = >100 μM for all).2Preterramide C inhibits the g...
T80330 XT-1
XT-1, an antimicrobial peptide sourced from Xenopus tropicalis skin secretions, exhibits potent activity against S. aureus, E. coli, and C. albicans, with minimum inhibitory concentration (MIC) values of 5, 6, and 50 μM,...
T79008 Ys-II
Compound 1 (Ys-II) is a spirostanol glycoside extracted from the stem of Yucca elephantipes, exhibiting antifungal properties by inhibiting Candida albicans and Cryptococcus neoformans growth with IC50 values of 5 and 6 ...
T72235 Antibacterial synergist 2
Antibacterial synergist 2, functioning as a biofilm inhibitor, demonstrates inhibitory effects against pathogens such as S. enterica, S. aureus, P. aeruginosa, and C. albicans. This compound is applicable in research con...
TN5014 Shoreic acid Antifection , HSV
Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, respectively, it also shows antifungal activity against C. albi...
TN3708 Coronarin D BCL , c-Myc , TNF , NF-κB , Caspase , COX , Antifection
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4 mg/mL, respectively; it is active again...
T37008 Reveromycin A
Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antip...
T36438 Sporogen-AO 1
Sporogen-AO 1 is a fungal metabolite originally isolated fromA. oryzaethat has diverse biological activities.1,2,3,4,5It inhibits HIV-1 Tat transactivation in a cell-based assay with an IC50value of 15.8 μM.4Sporogen-AO ...
T36886 Pestalotin
Pestalotin is a fungal metabolite originally isolated from P. cryptomeriaecola with diverse biological activities. It induces reducing sugar release in embryoless rice endosperms when used at concentrations ranging from ...
T36329 Terpendole I
Terpendole I is a fungal metabolite that has been found in A. yamanashiensis.1 It is a weak inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 145 μM) and is active against the bacteria B. cereus and ...
T83693 Magainin 2 TFA MG2
Magainin 2, a cationic peptide derived from the African clawed frog (X. laevis) skin, exhibits host defense and antimicrobial properties. This compound effectively inhibits a range of pathogens, including E. coli, K. pne...
TN4471 Lysicamine IL Receptor , Antifection
Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and a...

天然物製品

Fluconazole
T1388
Synonym: UK-49858
Target: Antibiotic, Antifection, Antifungal
Anandamide
T14046
Synonym: (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide
Target: Cannabinoid Receptor, Endogenous Metabolite
Pseudolaric Acid C
T7029
Synonym:
Target: Antifungal
Pachybasin
T37267
Synonym:
Target: Antibacterial
Lonicerin
TN1877
Synonym:
Target: Apoptosis, Antibacterial
Citric acid
T5S0636
Synonym: Citro,Citretten
Target: Apoptosis, Others, Endogenous Metabolite, Antibacterial, Antibiotic
Nystatin
T1678
Synonym: Stamycin,Fungicidin,Nystavescent
Target: Apoptosis, Antibiotic, Antifungal
2,2'-Dihydroxy chalcone
TN7224
Synonym:
Target: Antibacterial, Autophagy
(+)-Magnoflorine chloride
T4S1321
Synonym: Magnoflorine chloride,Corytuberine methochloride,Thalictrine chloride,Escholine chloride
Target: Others, Antifungal
(+)-Magnoflorine iodide
T3S1320
Synonym: Magnoflorine iodide,Thalictrine iodide,Corytuberine Methiodide
Target: Others, Antifungal
2-Phenylethanol
T0011
Synonym: Phenethyl alcohol,2-Phenylethyl alcohol,Benzyl carbinol,Phenylethanol,Benzeneethanol
Target: Others, Virus Protease, Antibacterial, Antibiotic
(+)-Magnoflorine
T3S1319
Synonym: Escholin,Magnoflorine,Thalictrin,Escholine
Target: Others, Antifungal
Lichesterol
T25718
Synonym:
Target:
Mutanocyclin
T79931
Synonym:
Target:
Luteolin-7-rutinoside
T11895
Synonym:
Target: Others
Pyridoxatin
T70891
Synonym:
Target:
Dehydroglaucine
TN1561
Synonym:
Target: Antifection
PF-1163B
T28379
Synonym: PF1163B,(-)-PF1163B,PF 1163B
Target:
Pachypodol
TN2032
Synonym:
Target: Antifection
Epitaraxerol
TN3978
Synonym:
Target: Antifection
1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone
TN2492
Synonym:
Target: Others
Altechromone A
TN3400
Synonym:
Target: Antifection
Fumiquinazoline D
T37712
Synonym:
Target:
Coronarin D ethyl ether
TN3709
Synonym:
Target: NF-κB
Aranorosin
T37444
Synonym:
Target:
Maximin H3
T80335
Synonym:
Target:
Cryptomeridiol
TN3723
Synonym:
Target: PAFR, Antifection
Hirsutide
T38016
Synonym:
Target:
Maximin H1
T80332
Synonym:
Target:
Maximin H2
T80334
Synonym:
Target:
Furanodiene
TN1651
Synonym:
Target: Apoptosis, PARP, Reactive Oxygen Species, Caspase, CDK, P-gp
Maximin H4
T80349
Synonym:
Target:
Verrucarin J
T69225
Synonym: Muconomycin B
Target:
Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate
T36403
Synonym:
Target:
XT-1
T80330
Synonym:
Target:
Ys-II
T79008
Synonym:
Target:
Antibacterial synergist 2
T72235
Synonym:
Target:
Shoreic acid
TN5014
Synonym:
Target: Antifection, HSV
Coronarin D
TN3708
Synonym:
Target: BCL, c-Myc, TNF, NF-κB, Caspase, COX, Antifection
Reveromycin A
T37008
Synonym:
Target:
Sporogen-AO 1
T36438
Synonym:
Target:
Pestalotin
T36886
Synonym:
Target:
Terpendole I
T36329
Synonym:
Target:
Magainin 2 TFA
T83693
Synonym: MG2
Target:
Lysicamine
TN4471
Synonym:
Target: IL Receptor, Antifection

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-00338 PRA1 Protein, Candida albicans, Recombinant (His) Candida albicans P. pastoris (Yeast)
PRA1 Protein, Candida albicans, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 33.4 kDa and the accession number is P87020.
TMPH-00336 GPD2 Protein, Candida albicans, Recombinant (His) Candida albicans P. pastoris (Yeast)
GPD2 Protein, Candida albicans, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 42.3 kDa and the accession number is Q59W33.
TMPH-00337 HWP1 Protein, Candida albicans, Recombinant (His) Candida albicans E. coli
HWP1 Protein, Candida albicans, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.2 kDa and the accession number is P46593.
TMPH-00334 Candidapepsin-6 Protein, Candida albicans, Recombinant (His) Candida albicans E. coli
Candidapepsin-6 Protein, Candida albicans, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.8 kDa and the accession number is P43095.
TMPH-00333 Candidapepsin-2 Protein, Candida albicans, Recombinant (His) Candida albicans E. coli
Candidapepsin-2 Protein, Candida albicans, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 42.4 kDa and the accession number is P0CS83.
TMPH-00335 FBA1 Protein, Candida albicans, Recombinant (His & Myc) Candida albicans E. coli
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in gl...
TMPH-00331 ALS3 Protein, Candida albicans, Recombinant (B2M & His & Myc) Candida albicans E. coli
Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans...
TMPH-00330 Acetyl-CoA carboxylase Protein, Candida albicans, Recombinant (His) Candida albicans E. coli
Acetyl-CoA carboxylase Protein, Candida albicans, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 67.3 kDa and the accession number is A0A1D8PRR7.
TMPH-00332 Candidapepsin-2 Protein, Candida albicans (strain WO-1), Recombinant (His) Candida albicans E. coli
Candidapepsin-2 Protein, Candida albicans (strain WO-1), Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 42.3 kDa and the accession number is C4YMJ3.