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阻害剤

天然化合物

148

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T3638	Leukadherin-1		Integrin , Complement System
	Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendothelial migration; reduces inflammation.		Integrin , Complement System
T4435	E7820	ER68203-00	Integrin
	E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).		Integrin
T16571	Pranidipine	OPC-13340	Calcium Channel
	Pranidipine (OPC-13340) is a novel, long-acting 1,4-dihydropyridine calcium channel blocker. It prolongs acetylcholine-induced relaxation in presence of endothelium as well as nitroglycerin-induced relaxation in absence ...		Calcium Channel
T34541	SB-209670	SB 209670	Endothelin Receptor
	SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in rat vascular endothelium and vascular smooth muscle.		Endothelin Receptor
T14942	CGP48369		RAAS
	CGP48369 is a potent angiotensin II receptor antagonist with antihypertensive effects that enhances endothelium-dependent relaxation of coronary arteries in spontaneously hypertensive rats.		RAAS
T0370	Pheniramine maleate	Daneral,Inhiston,Trimetose	5-HT Receptor , Histamine Receptor
	Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re...		5-HT Receptor , Histamine Receptor
T6264	Bosentan	Actelion,Ro 47-0203,Benzenesulfonamide	Endothelin Receptor
	Bosentan (Benzenesulfonamide) is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks th...		Endothelin Receptor
TP1277	Bradykinin		Endogenous Metabolite , Bradykinin Receptor
	Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge) via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor. Bradykinin is a physiol...		Endogenous Metabolite , Bradykinin Receptor
T4567	Sulfaphenazole	Plisulfan,Raziosulfa,Depocid,Depotsulfonamide	P450 , Antibacterial
	Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1...		P450 , Antibacterial
T27574	ZM 169369	ICI169369,ICI-169369
	ICI 169369, a 5-HT2/5-HT1C antagonist, can evoke endothelium-dependent relaxation in rabbit aorta.
T83164	Adrenomedullin (porcine)
	Adrenomedullin (porcine) is a vasodilatory peptide that elicits endothelium-dependent relaxation in rat aorta at an IC50 of 2.4 nM and also induces endothelium-independent relaxation in porcine coronary arteries, with an...
T76421	Protein Kinase C β Peptide
	Protein Kinase C (beta) Peptide, a fragment of Protein Kinase Cβ, is associated with hyperglycemia-induced decreases in endothelium-derived nitric oxide. Inhibiting Protein Kinase Cβ forestalls the impairment of endothel...
T26589	Albifylline
	Albifylline is a xanthine derivates with anti-asthmatic activity. Albifylline may cause a significant reduction of shock-induced leukocyte adhesions to the sinusoidal endothelium in the liver after hemorrhagic shock. Alb...
T25748	L-Nabe	N(w)-nitroarginine benzyl ester,H-Arg(NO2)-Obzl,N-Nitro-L-argininebenzyl ester,NABE,Benzyl Nw-nitro-L-argininate	Others
	L-Nabe (H-Arg(NO2)-Obzl) is a effective irreversible endothelium dependent relaxation inhibitor.		Others
TP1919	Ac2-12
	Annexin/lipocortin 1-mimetic peptide; inhibits leukocyte extravasation. Reduces neutrophil adhesion and emigration, and promotes detachment of neutrophils from activated mesenteric endothelium in mice in vivo.
T36151	14,15-EE-8(Z)-E
	Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity....
T76841	Enlimomab
	Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody targeting human ICAM-1, reduces leukocyte adhesion to the vascular endothelium, thus diminishing leukocyte extravasation and inflammatory tissue damage. This com...
T75154	ATU027
	ATU027, a small interfering RNA (siRNA), silences protein kinase N3 (PKN3) expression in the vascular endothelium. It has been demonstrated to thwart local tumor invasion, as well as lymph node and pulmonary metastasis, ...
T70903	KRH102053
	KRH102053 is a HIF-1alpha inhibitor. KRH102053 decreased the protein level of HIF-1alpha and the mRNA levels of HIF-regulated downstream target genes, such as vascular endothelial growth factor, aldolase A, enolase 1 an...
T67212	Ligustrazine HCl
	Ligustrazine Hydrochloride, is a natural substance discovered in the plant Ligusticum chuanxiong Hort. It inhibits platelet aggregation, improves atherosclerosis situation, protects endothelium injury, and has antithromb...
T41251	Taprostene
	Taprostene (CG-4203), a synthetic and chemically stable analogue of Prostacyclin (PGI2), effectively protects the endothelium and myocardium following acute myocardial ischemia and reperfusion in cats. It enhances cytopr...
T68511	KRH102140
	KRH102140 is a potent activator of PHD2. KRH102140, which has a structure similar to KRH102053. KRH102140 more efficiently suppressed HIF-1α than KRH102053 in human osteosarcoma cells under hypoxia. Furthermore, KRH10214...
T36150	14,15-EE-5(Z)-E
	Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity....
T35600	NO-Losartan A
	Angiotensin II is a hormone that plays an important role in regulating blood pressure. Elevated levels of angiotensin II are implicated in inducing and maintaining hypertension, and also in the development of atheroscler...
T37234	(±)14(15)-EpETE
	EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de...
T37235	(±)16(17)-EpDPA	(±)16,17-EpDPE,(±)16,17 EDP,(±)16,17-epoxy Docosapentaenoic Acid,(±)16,17-epoxy DPA,(±)16(17)-EpDPA
	EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de...
T82683	Connexin mimetic peptide 40GAP27
	Connexin mimetic peptide 40GAP27, corresponding to the GAP27 domain of the second extracellular loop of the dominant vascular connexin (Cx40), designated as 40Gap27, is a biologically active peptide utilized to study the...
T35464	(±)14(15)-EET-SI
	Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes. The EETs are released in response to acetylcholine, bradykinin, arachidonic acid, or cyclic...
T36074	S-NEPC
	Cytochrome P450 metabolites of arachidonic acid, such as 11(12)-EpETrE and 14(15)-EpETrE have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) cata...
T37969	12(S)-HpETE
	12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It activates human blood leukocyte 5-LO, resulting in the sy...
T37238	(±)19(20)-EpDPA
	EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de...
T82789	Caloxin 1B1
	Caloxin 1B1, a bioactive peptide, exhibits selective inhibition of PMCA extracellularly by binding preferentially to the extracellular domain 1 of PMCA4 over PMCA1. Identified through a screening process for its high-aff...
T70456	Nolpitantium Free Base
	Nolpitantium Free Base is a highly selective nonpeptide antagonist of neurokinin-1 (NK1) receptor. Nolpitantium potently, selectively and competitively inhibited substance P binding to NK1 receptors from various animal s...
T82684	Connexin mimetic peptide 40,37GAP26
	Connexin mimetic peptide 40,37GAP26, a biologically active peptide, matches the GAP26 domain of the extracellular loop of major vascular connexins Cx37 and Cx40, referred to as 37,40Gap26 based on Cx homology. It has bee...
T35598	Neuromedin U-25 (human) (trifluoroacetate salt)
	Neuromedin U (NMU) is a neuropeptide first demonstrated to drive smooth muscle contraction.1Translated as a 174 amino acid propeptide, NMU is cleaved to different lengths in different animals. It has diverse receptor-med...
T37495	Angiotensin (1-7) (acetate)
	Angiotensin 1-7 (Ang-(1-7)) acetate, an endogenous heptapeptide from the renin-angiotensin system (RAS), exhibits cardioprotective effects through its anti-inflammatory and anti-fibrotic activities in cardiac cells. It e...

Compounds

Leukadherin-1

T3638

Synonym:

Target: Integrin, Complement System

Target: Calcium Channel

SB-209670

T34541

Synonym: SB 209670

Target: Endothelin Receptor

Synonym: Daneral,Inhiston,Trimetose

Target: 5-HT Receptor, Histamine Receptor

Bosentan

T6264

Synonym: Actelion,Ro 47-0203,Benzenesulfonamide

Target: Endothelin Receptor

Bradykinin

TP1277

Synonym:

Target: Endogenous Metabolite, Bradykinin Receptor

Sulfaphenazole

T4567

Synonym: Plisulfan,Raziosulfa,Depocid,Depotsulfonamide

Target: P450, Antibacterial

ZM 169369

T27574

Synonym: ICI169369,ICI-169369

Target:

Adrenomedullin (porcine)

T83164

Synonym:

Target:

Protein Kinase C β Peptide

Synonym: N(w)-nitroarginine benzyl ester,H-Arg(NO2)-Obzl,N-Nitro-L-argininebenzyl ester,NABE,Benzyl Nw-nitro-L-argininate

Synonym: (±)16,17-EpDPE,(±)16,17 EDP,(±)16,17-epoxy Docosapentaenoic Acid,(±)16,17-epoxy DPA,(±)16(17)-EpDPA

Target:

Connexin mimetic peptide 40GAP27

Nolpitantium Free Base

T70456

Synonym:

Target:

Connexin mimetic peptide 40,37GAP26

T82684

Synonym:

Target:

Neuromedin U-25 (human) (trifluoroacetate salt)

T35598

Synonym:

Target:

Angiotensin (1-7) (acetate)

T37495

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T3927	Phellopterin		GABA Receptor
	Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. Phellopterin shows a cytotoxic effect on RAW264.7 cell at the concentration from 40 to 400 μM. Phellopterin reduce TNF-alpha-induced VCA...		GABA Receptor
TMS2171	(±)-Naringenin	Salipurpol,Naringenine,Naringenin	Potassium Channel
	(±)-Naringenin (Naringenine) is a natural product. It displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes.		Potassium Channel
T38248	2-Ethylpyrazine		Endogenous Metabolite , NO Synthase
	2-Ethylpyrazine is present in roasted coffee beans and is a volatile compound .2-Ethylpyrazine induces vasodilation through the activity of endothelium-derived relaxing factors.2-Ethylpyrazine activates NO synthesis thro...		Endogenous Metabolite , NO Synthase
T4809	Pyrimidine	Metadiazine	Others , Endogenous Metabolite
	Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ...		Others , Endogenous Metabolite
T37974	(S)-Coriolic acid	13(S)-HODE	Lipoxygenase , Mitochondrial Metabolism , PPAR
	(S)-Coriolic acid (13(S)-HODE) is an important intracellular signaling agent, generated by the reaction of linoleic acid with plant and mammalian lipoxygenases, and is involved in cell proliferation and differentiation i...		Lipoxygenase , Mitochondrial Metabolism , PPAR
TN1567	Delphinidin chloride		Estrogen Receptor/ERR , VEGFR
	Delphinidin chloride, a natural plant pigment found in berries and red wine, is a precursor of certain anthocyanins. Delphinidin chloride induces the release of nitric oxide from the vascular endothelium, resulting in va...		Estrogen Receptor/ERR , VEGFR
T3794	Pentagalloylglucose	Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose	Influenza Virus
	1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten...		Influenza Virus
TN1246	3-Deoxysappanone B		Others
	3-Deoxysappanone B has vasorelaxation effects, it can mediate endothelium- independent vasodilator action in rat thoracic aortic rings.		Others
TN2534	1-Hydroxy-2,3,5-trimethoxyxanthone		IκB/IKK , Calcium Channel , NOS , 5-HT Receptor , COX
	1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independent mechanism by inhibiting Ca(2+) influx through L-type vo...		IκB/IKK , Calcium Channel , NOS , 5-HT Receptor , COX
TN4819	(-)-Praeruptorin A		ATPase , IL Receptor , Calcium Channel , P-gp
	(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis;it also can ...		ATPase , IL Receptor , Calcium Channel , P-gp
T81324	Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside
	Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside, an orally active phenolic compound extracted from the Geranium species, exhibits anti-inflammatory properties. It shows promise for use in treatments involving edema and...

天然物製品

Phellopterin

T3927

Synonym:

Target: GABA Receptor

(±)-Naringenin

TMS2171

Synonym: Salipurpol,Naringenine,Naringenin

Target: Potassium Channel

2-Ethylpyrazine

T38248

Synonym:

Target: Endogenous Metabolite, NO Synthase

Pyrimidine

T4809

Synonym: Metadiazine

Target: Others, Endogenous Metabolite

(S)-Coriolic acid

T37974

Synonym: 13(S)-HODE

Target: Lipoxygenase, Mitochondrial Metabolism, PPAR

Delphinidin chloride

TN1567

Synonym:

Target: Estrogen Receptor/ERR, VEGFR

Pentagalloylglucose

T3794

Synonym: Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose

Target: Influenza Virus

1-Hydroxy-2,3,5-trimethoxyxanthone

TN2534

Synonym:

Target: IκB/IKK, Calcium Channel, NOS, 5-HT Receptor, COX

(-)-Praeruptorin A

TN4819

Synonym:

Target: ATPase, IL Receptor, Calcium Channel, P-gp

Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside

T81324

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03305	VE-Cadherin Protein, Rat, Recombinant (His)	Rat	HEK293
	Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in ...
TMPY-01677	VE-Cadherin Protein, Human, Recombinant (His & hFc)	Human	HEK293
	Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in ...
TMPY-01237	VE-Cadherin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in ...
TMPY-03848	Protein S/PROS1 Protein, Human, Recombinant (His)	Human	HEK293
	PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free,...
TMPY-01167	E-Selectin/CD62E Protein, Human, Recombinant (His)	Human	HEK293
	E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involv...
TMPY-01851	CD73 Protein, Human, Recombinant (His)	Human	HEK293
	5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-03377	CD73 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-00381	PSMA Protein, Human, Recombinant (His)	Human	HEK293
	Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPY-01342	CD73 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-03540	CD73 Protein, Rat, Recombinant (His)	Rat	HEK293
	5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-02033	CD44 Protein, Human, Recombinant (His)	Human	HEK293
	CD44 is a type I transmembrane protein and a member of the cartilage link protein family. It is involved in cell-cell and cell-matrix interactions and signal transduction. Several CD44 ligands have been identified. The m...
TMPY-05047	CD44 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD44 is a type I transmembrane protein and a member of the cartilage link protein family. It is involved in cell-cell and cell-matrix interactions and signal transduction. Several CD44 ligands have been identified. The m...
TMPY-05827	PD-L2 Protein, Human, Recombinant (mFc)	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-03763	Neuropilin-2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-00892	Neuropilin-2 Protein, Human, Recombinant (His)	Human	HEK293
	Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-04957	PD-L2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-02234	CXCL9 Protein, Human, Recombinant	Human	E. coli
	Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defi...
TMPY-04346	PD-L2 Protein, Human, Recombinant (His)	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-01032	CD299 Protein, Human, Recombinant (hFc)	Human	HEK293
	C-type lectin domain family 4, member M, also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein that is 77% amino acid identical to DC-SIGN, an HIV gp120-binding protein. Though the encoded gene locate...
TMPY-01379	DLL1 Protein, Human, Recombinant (His)	Human	HEK293
	Delta-like protein 1(DLL1), also known as Delta1, a single-pass type I membrane protein which contains one DSL domain and eight EGF-like domains, acts as a ligand for Notch receptors, and positively regulates T-cell deve...
TMPY-01915	DLL1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Delta-like protein 1(DLL1), also known as Delta1, a single-pass type I membrane protein which contains one DSL domain and eight EGF-like domains, acts as a ligand for Notch receptors, and positively regulates T-cell deve...
TMPY-01059	BMPR2 Protein, Human, Recombinant (His)	Human	HEK293
	The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPY-01253	LAMP1 Protein, Human, Recombinant (His)	Human	HEK293
	Lysosome-associated membrane glycoprotein 1, also known as CD107 antigen-like family member A, CD107a, and LAMP1, is a single-pass type I membrane protein that belongs to the LAMP family. CD107a is expressed largely in t...
TMPY-05833	DLL1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Delta-like protein 1(DLL1), also known as Delta1, a single-pass type I membrane protein which contains one DSL domain and eight EGF-like domains, acts as a ligand for Notch receptors, and positively regulates T-cell deve...
TMPY-05337	CXCL16 Protein, Human, Recombinant (His)	Human	HEK293
	C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmemb...
TMPH-03286	Endothelin-1/EDN1 Protein, Rat, Recombinant (His & KSI)	Rat	E. coli
	Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial...
TMPH-02316	YJEFN3 Protein, Human, Recombinant	Human	E. coli
	May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endotheli...
TMPH-01295	Endothelin-1/EDN1 Protein, Human, Recombinant (GST)	Human	E. coli
	Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial...
TMPK-00223	Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is highly distinct from its role in the endothelium. Ephrin-B2 ...
TMPH-00343	Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His)	Canine	HEK293
	Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal i...
TMPH-03239	Angiopoietin-1 Protein, Rat, Recombinant (His)	Rat	HEK293
	Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal i...
TMPJ-00564	PLXDC2 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Mouse Plexin domain-containing protein 2(PLXDC2) is a single-pass type I membrane protein. The protein is expressed in tumor endothelium and in vessels of some normal tissues, such as the muscle and lung. PLXDC2 can inte...
TMPK-00349	E-Selectin/CD62E Protein, Human, Recombinant (His & Avi)	Human	HEK293
	E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response ...
TMPK-00350	E-Selectin/CD62E Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response ...
TMPK-00487	E-selectin/CD62E Protein, Cynomolgus, Recombinant (aa 22-554, His)	Cynomolgus	HEK293
	E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response ...
TMPY-06716	CD34 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-03031	CD34 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPJ-01193	CLM-9 Protein, Human, Recombinant (aa 19-247, His)	Human	Human Cells
	CMRF35-Like Molecule 9 (CD300LG) is a single-pass type I membrane protein which belongs to the CD300 family. CD300LG has one Ig-like V-type domain which mediates binding to lymphocyte. CD300LG is highly expressed in hear...
TMPK-00359	Endoglin/CD105 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis...
TMPY-01652	CD34 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-00708	CD34 Protein, Human, Recombinant (hFc)	Human	HEK293
	Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-06708	Protein S/PROS1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free,...
TMPY-00709	CD34 Protein, Human, Recombinant (His)	Human	HEK293
	Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-06764	CD34 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-05772	CD34 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-05582	CD34 Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293
	Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPJ-00257	PSGL-1/CD162 Protein, Human, Recombinant (hFc)	Human	Human Cells
	PSGL-1 (CD162), is a mucintype glycoprotein that plays a key role in leukocyte adhesion. Human PSGL-1 cDNA encodes 412 amino acids (aa). It expressed on neutrophils, monocytes and most lymphocytes. The mature PSGL-1 (aa ...
TMPY-00517	LSP1 Protein, Human, Recombinant (His)	Human	HEK293
	LSP1 (Lymphocyte Specific Protein 1) is a Protein Coding gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regula...
TMPY-06315	Protein S/PROS1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free,...
TMPY-02079	E-Selectin/CD62E Protein, Rat, Recombinant (His)	Rat	HEK293
	E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involv...
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VE-Cadherin Protein, Rat, Recombinant (His)

TMPY-03305

Species: Rat

Expression System: HEK293

VE-Cadherin Protein, Human, Recombinant (His & hFc)

TMPY-01677

Species: Human

Expression System: HEK293

VE-Cadherin Protein, Mouse, Recombinant (His)

TMPY-01237

Species: Mouse

Expression System: HEK293

Protein S/PROS1 Protein, Human, Recombinant (His)

TMPY-03848

Species: Human

Expression System: HEK293

E-Selectin/CD62E Protein, Human, Recombinant (His)

TMPY-01167

Species: Human

Expression System: HEK293

CD73 Protein, Human, Recombinant (His)

TMPY-01851

Species: Human

Expression System: HEK293

CD73 Protein, Cynomolgus, Recombinant (His)

TMPY-03377

Species: Cynomolgus

Expression System: HEK293

PSMA Protein, Human, Recombinant (His)

TMPY-00381

Species: Human

Expression System: HEK293

CD73 Protein, Mouse, Recombinant (His)

TMPY-01342

Species: Mouse

Expression System: HEK293

CD73 Protein, Rat, Recombinant (His)

TMPY-03540

Species: Rat

Expression System: HEK293

CD44 Protein, Human, Recombinant (His)

TMPY-02033

Species: Human

Expression System: HEK293

CD44 Protein, Mouse, Recombinant (His)

TMPY-05047

Species: Mouse

Expression System: HEK293

PD-L2 Protein, Human, Recombinant (mFc)

TMPY-05827

Species: Human

Expression System: HEK293

Neuropilin-2 Protein, Human, Recombinant (hFc)

TMPY-03763

Species: Human

Expression System: HEK293

Neuropilin-2 Protein, Human, Recombinant (His)

TMPY-00892

Species: Human

Expression System: HEK293

PD-L2 Protein, Human, Recombinant (His), Biotinylated

TMPY-04957

Species: Human

Expression System: HEK293

CXCL9 Protein, Human, Recombinant

TMPY-02234

Species: Human

Expression System: E. coli

PD-L2 Protein, Human, Recombinant (His)

TMPY-04346

Species: Human

Expression System: HEK293

CD299 Protein, Human, Recombinant (hFc)

TMPY-01032

Species: Human

Expression System: HEK293

DLL1 Protein, Human, Recombinant (His)

TMPY-01379

Species: Human

Expression System: HEK293

DLL1 Protein, Mouse, Recombinant (His)

TMPY-01915

Species: Mouse

Expression System: HEK293

BMPR2 Protein, Human, Recombinant (His)

TMPY-01059

Species: Human

Expression System: HEK293

LAMP1 Protein, Human, Recombinant (His)

TMPY-01253

Species: Human

Expression System: HEK293

DLL1 Protein, Human, Recombinant (hFc)

TMPY-05833

Species: Human

Expression System: HEK293

CXCL16 Protein, Human, Recombinant (His)

TMPY-05337

Species: Human

Expression System: HEK293

Endothelin-1/EDN1 Protein, Rat, Recombinant (His & KSI)

TMPH-03286

Species: Rat

Expression System: E. coli

YJEFN3 Protein, Human, Recombinant

TMPH-02316

Species: Human

Expression System: E. coli

Endothelin-1/EDN1 Protein, Human, Recombinant (GST)

TMPH-01295

Species: Human

Expression System: E. coli

Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc)

TMPK-00223

Species: Human

Expression System: HEK293

Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His)

TMPH-00343

Species: Canine

Expression System: HEK293

Angiopoietin-1 Protein, Rat, Recombinant (His)

TMPH-03239

Species: Rat

Expression System: HEK293

PLXDC2 Protein, Mouse, Recombinant (His)

TMPJ-00564

Species: Mouse

Expression System: Human Cells

E-Selectin/CD62E Protein, Human, Recombinant (His & Avi)

TMPK-00349

Species: Human

Expression System: HEK293

E-Selectin/CD62E Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00350

Species: Human

Expression System: HEK293

E-selectin/CD62E Protein, Cynomolgus, Recombinant (aa 22-554, His)

TMPK-00487

Species: Cynomolgus

Expression System: HEK293

CD34 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06716

Species: Human

Expression System: HEK293

CD34 Protein, Rat, Recombinant (hFc)

TMPY-03031

Species: Rat

Expression System: HEK293

CLM-9 Protein, Human, Recombinant (aa 19-247, His)

TMPJ-01193

Species: Human

Expression System: Human Cells

Endoglin/CD105 Protein, Human, Recombinant (His & Avi)

TMPK-00359

Species: Human

Expression System: HEK293

CD34 Protein, Mouse, Recombinant (His)

TMPY-01652

Species: Mouse

Expression System: HEK293

CD34 Protein, Human, Recombinant (hFc)

TMPY-00708

Species: Human

Expression System: HEK293

Protein S/PROS1 Protein, Mouse, Recombinant (His)

TMPY-06708

Species: Mouse

Expression System: HEK293

CD34 Protein, Human, Recombinant (His)

TMPY-00709

Species: Human

Expression System: HEK293

CD34 Protein, Mouse, Recombinant (hFc)

TMPY-06764

Species: Mouse

Expression System: HEK293

CD34 Protein, Human, Recombinant (His), Biotinylated

TMPY-05772

Species: Human

Expression System: HEK293

CD34 Protein, Human, Recombinant (hFc), Biotinylated

TMPY-05582

Species: Human

Expression System: HEK293

PSGL-1/CD162 Protein, Human, Recombinant (hFc)

TMPJ-00257

Species: Human

Expression System: Human Cells

LSP1 Protein, Human, Recombinant (His)

TMPY-00517

Species: Human

Expression System: HEK293

Protein S/PROS1 Protein, Cynomolgus, Recombinant (His)

TMPY-06315

Species: Cynomolgus

Expression System: HEK293

E-Selectin/CD62E Protein, Rat, Recombinant (His)

TMPY-02079

Species: Rat

Expression System: HEK293

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カタログ番号	製品名
L7500	Coagulation and Anticoagulation Compound Library		154 compounds
	A unique collection of 154 procoagulation and anticoagulation related compounds for high throughput screening (HTS) and high content screening (HCS);

ライブラリー

Coagulation and Anticoagulation Compound Library

L7500

Compounds: 154