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Search Results for " glioma "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T17208	USL311		CXCR
	USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing...		CXCR
T14214	AMG 511		PI3K
	AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks(Kis of 4 nM, 6 nM, 2 nM and 1 nM for PI3Kα, β, δ and γ, respectively). It exhibits anti-tumor activity in mouse glioblastoma xenograft model[1]. AMG...		PI3K
T17158	Trans-AUCB	t-AUCB	Epoxide Hydrolase
	trans-AUCB (t-AUCB) is an effective and selective soluble epoxide hydrolase inhibitor (IC50s: 1.3 nM, 8 nM, 8 nM for hsEH, mouse sEH and rat sEH, respectively).		Epoxide Hydrolase
T3213	Hematoporphyrin dihydrochloride	Hematoporphyrin IX dihydrochloride	Apoptosis , Others , Endogenous Metabolite
	Hematoporphyrin dihydrochloride (Hematoporphyrin IX dihydrochloride) is a substrate for affinity chromatography of heme-binding proteins.		Apoptosis , Others , Endogenous Metabolite
T8742	G5-7	JAK2 inhibitor G5-7	Apoptosis , JAK
	JAK2 inhibitor G5-7 (JAK2 inhibitor G5-7) is an orally active JAK2 inhibitor, selectively inhibits JAK2–mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 has the potential for g...		Apoptosis , JAK
T1944	LDN-214117		ALK , TGF-beta/Smad
	LDN-214117 is a potent and selective ALK2 inhibitor.		ALK , TGF-beta/Smad
T1158	Phenoxybenzamine hydrochloride	NCI-c01661,NSC 37448,Phenoxybenzamine HCl	CaMK , Adrenergic Receptor
	Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non...		CaMK , Adrenergic Receptor
T6920	ON123300		FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
	ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).		FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
T2028	NG 52	NG52,NG-52,Compound 52	CDK
	NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.		CDK
T7008	Vacquinol-1	Vacquinol 1	JNK
	Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.		JNK
T23480	U-83836E		Others
	U-83836E (lazaroid ) has neuroprotective activity and anti-tumor activity, inhibits glioma cell proliferation, inhibits tumor necrosis factor and reverses endotoxin-induced shock.		Others
T61051	ANO1-IN-1		Chloride channel
	ANO1-IN-1, a selective ANO1 channel blocker, inhibited ANO1 and ANO2 with IC50 values of 2.56 μM and 15.43 μM, respectively.ANO1-IN-1 had a significant inhibitory effect on the proliferation of glioma cells.		Chloride channel
T20025	Imipramine	HSDB 3100,Melipramine,HSDB3100,Dimipressin,HSDB-3100	Apoptosis
	Imipramine (Dimipressin) is an orally active Fascin1 inhibitor with antidepressant and antitumor activity.Imipramine inhibits the 5-hydroxytryptamine transporter (IC50: 32 nM), induces apoptosis, and induces autophagy in...		Apoptosis
T14126	ADDA 5 hydrochloride		Others
			Others
T28195	NS004	NS 004,NS-004
	NS004 is a large-conductance K+ channel opener, it inhibits mitochondrial function in glioma cells.
T28173	NIK-250	NIK250
	NIK-250 is a P-glycoprotein inhibitor. NIK250 could reverse multidrug resistance in human glioma cells.
T26493	AA 863	AA-863
	AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.
T28048	Mivobulin Isethionate	NSC-613863,CI-980,NSC-635370,NSC-613862,NSC-350386
	Mivobulin is a tubulin inhibitor potentially for the treatment of glioma, malignant melanoma, prostate, ovarian cancer. CI-980 acts at the colchicine-binding site.
T21842	2-fluoro Palmitic Acid
	2-Fluoropalmitic acid, functioning as an acyl-CoA synthetase inhibitor, is a potential anti-glioma agent. It diminishes the viability and stem-like characteristics of glioma stem cells (GSCs) and hinders the proliferatio...
T24920	UCD38B HCl	UCD38B hydrochloride,UCD 38 B hydrochloride,UCD-38-B HCl,UCD-38-B Hydrochloride,UCD 38 B HCl
	UCD38B HCl is a cell-permeable intracellular uPA inhibitor that acts by killing proliferative and non-proliferative high-grade glioma cells by programmed necrosis.
T60661	CP681301
	CP681301 is a potent inhibitor of CDK5 with antiproliferative activity. CP681301 exhibits anti-tumor activity in Drosophila. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in Glioma st...
T68324	KCN1
	KCN1, a novel synthetic sulfonamide, is a HIF pathway inhibitor with potential anticancer activity in vitro and in vivo anti-pancreatic cancer activities and preclinical pharmacology. KCN1 specifically inhibited HIF repo...
TP1589	EGFRvIII peptide (PEPvIII)	EGFRvIII peptide PEPvIII
	PEPvIII, a peptide sequence from EGFRvIII, was designed to represent a target of glioma and is presented by MHC I/II complexes.
T74365	Chol-CTPP
	Chol-CTPP, a ligand with a dual targeting effect on the blood-brain barrier (BBB) and glioma cells, serves as the precursor to Lip-CTPP when combined with another mitochondria-targeting ligand (Chol-TPP). Lip-CTPP emerge...
T61958	MAO A/HDAC-IN-1
	MAO A/HDAC-IN-1 is an effective monoamine oxidase A (MAO A) and HDAC dual inhibitor, which can be used for glioma research.
T36407	Pyrrolidine Ricinoleamide
	Ricinoleic acid is a naturally occurring 12-hydroxy fatty acid. It constitutes about 90% of the fatty acids in castor oil. Pyrrolidine Ricinoleamide is a derivative of the amide of ricinoleic acid that shows potent antip...
T38970	Hematoporphyrin monomethyl ether
	Hematoporphyrin monomethyl ether (HMME), a second-generation porphyrin-related photosensitizer, is a highly selective and low-toxicity compound known for its singular form and high yield of singlet oxygen. It finds exten...
T36449	(S)-α-Methylbenzyl Ricinoleamide
	(S)-α-Methylbenzyl ricinoleamide is a fatty acid amide derived from ricinoleic acid and methyl benzylamine. It demonstrates potent growth inhibition of glioma (U251), breast (MCF-7), ovarian (NCI-ADR/RES and OVCAR-3), ki...
T41212	FTI 277
	FTI 277 is a prodrug form of FTI 276 that inhibits farnesyltransferase (FTase) (IC50 = 0.5 nM). Inhibits H-Ras and K-Ras processing in whole cells (IC50 values are 0.1 and 10μM respectively) and disrupts constitutive H-R...
T77112	Onfekafusp alfa
	Onfekafusp alfa (L19TNF) is an engineered homotrimer consisting of L19 antibody peptides in scFv format fused to human TNF, utilized for research in malignant glioma [1] [2].
T35558	KAAD-Cyclopamine
	Cyclopamine-KAAD is a potent inhibitor of hedgehog signaling with an IC50 value of 20 nM in a Shh-LIGHT2 assay. It blocks binding of BODIPY-cyclopamine to cells expressing Smoothened (Smo) in a dose-dependent manner. Cyc...
T41204	TAT-Gap19(I130A)	TAT-Gap19(I130A)
	TAT-Gap19(I130A) is a control peptide for TAT-Gap19, a Cx43 hemichannel blocker. TAT-Gap19(I130A) consists of TAT-GAP19 with a I130A amino acid residue change at a key residue for GAP19 activity. In C6 glioma cells expre...
TP1935	RAGE antagonist peptide
	Receptor for advanced glycation end products (RAGE) antagonist. Blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Inhibits growth and metastasis of rat glioma tumors. Reduces cell growth and ...
T35947	17(S)-HDHA
	17(S)-HDHA is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and mouse brain. 17(S)-HDHA serves as a precursor to 17(S)-resolvins and has intrinsic biological activity,...
T36406	Pyrrolidine Linoleamide
	Linoleic acid is an essential fatty acid and one of the most abundant polyunsaturated fatty acids in the western diet. Pyrrolidine Linoleamide is a derivative of the amide of linoleic acid that shows potent antiprolifera...
T36042	17(R)-HDHA
	Resolvins are a group of polyhydroxylated metabolites of docosahexaenoic acid (DHA) found in the inflammatory exudates of aspirin-treated experimental animals. 17(R)-HDHA is the primary oxygenation product of DHA when ex...
T62725	IDH1 Inhibitor 5
	IDH1 Inhibitor 5 (compound 2) is an inhibitor of IDH1 (isocitrate dehydrogenase 1), which inhibits MOG cells (IC50: 64.4 nM) and wild-type IDH1 glioma cells expressing exogenous mutant IDH1 R132H protein (IC50: 34.9 nM).
T37431	ENPP1 Inhibitor C	ENPP1 Inhibitor C
	ENPP1 inhibitor C is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50 = 0.26 μM in a cell-free assay).1 It is selective for ENPP1 over ENPP2-7 at 10 μM. ENPP1 inhibitor C decreases ENPP1 ac...
T35542	LLP-3
	Survivin (also known as baculoviral IAP repeat-containing protein 5 (BIRC5)) is a member of the inhibitor of apoptosis (IAP) family that interacts with and inhibits the apoptotic function of several proteins. LLP-3 is a ...
T78124	SF2312 ammonium		Antibiotic
	SF2312 ammonium is the ammonium salt of SF2312, a phosphonate antibiotic and enolase inhibitor derived from the actinomycete Micromonospora and active under anaerobic conditions. Notably, SF2312 exhibits selective toxici...		Antibiotic
T8792	SMBA1
	SMBA1 is a Bax activator and a potent Bax agonist (Ki : 43.3 nM) that induces cell cycle arrest and apoptosis in malignant glioma cells.SMBA1 has shown antitumor activity by enhancing Bax expression.SMBA1 can be used in ...
T62342	CSF1R-IN-4
	CSF1R-IN-4 is a potent inhibitor of CSF-1R. CSF1R-IN-4 can affect the exchange of inflammatory factors between TAM and glioma cells. CSF1R-IN-4 has potential for the study of cancer diseases. EGFR-IN-40.
T36323	C8 Galactosylceramide (d18:1/8:0)	C8 Galactosylceramide (d18:1/8:0)
	C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids. It increases the amount delivered and toxicity of doxorubicin in cancerous but not non-cancerous cells w...
T62364	CSF1R-IN-5
	CSF1R-IN-5 is a potent inhibitor of CSF1R. CSF1R-IN-5 can affect the exchange of inflammatory factors between TAM and glioma cells. CSF1R-IN-5 has the potential to be used in the study of cancer diseases.
T78877	MTX-241F		EGFR
	MTX-241F, a selective small molecule inhibitor, targets members of the EGFR and PI3 kinase families. It penetrates the blood-brain barrier, providing long-term tumor growth control and exhibits radiosensitizing activity ...		EGFR
T35573	Adenosine 5’-methylenediphosphate (hydrate)
	Adenosine 5’-methylenediphosphate is an inhibitor of ecto-5’-nucleotidase, also known as CD73, with a Kivalue of 37 nM.1It inhibits cAMP accumulation induced by adenosine 5’-monophosphate , adenosine 5’-diphosphate , or ...
T78450	4-Di-1-ASP
	4-Di-1-ASP, a styryl dye, selectively stains glioma cells within live brain tissue, facilitating microscopic analysis of cell structure, viability, and processes including proliferation, endocytosis, cytokinesis, and pha...
T82049	IR-Crizotinib		NF-κB
	IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 μM for intracranial glioblastoma (GBM) localization in mice. It has the ability...		NF-κB
T83741	S7 TFA	Leu-Ser-Leu-Iso-Thr-Arg-Leu-OH
	S7, a peptide antagonist of the IL-6 receptor, concentration-dependently inhibits IL-6 binding to its receptor. At 50 µM, S7 suppresses IL-6-triggered elevations in VEGF levels within C-33 A cervical cancer cells and RPM...

Compounds

Target: Epoxide Hydrolase

Hematoporphyrin dihydrochloride

T3213

Synonym: Hematoporphyrin IX dihydrochloride

Target: Apoptosis, Others, Endogenous Metabolite

G5-7

T8742

Synonym: JAK2 inhibitor G5-7

Target: Apoptosis, JAK

LDN-214117

T1944

Synonym:

Target: ALK, TGF-beta/Smad

Phenoxybenzamine hydrochloride

T1158

Synonym: NCI-c01661,NSC 37448,Phenoxybenzamine HCl

Target: CaMK, Adrenergic Receptor

ON123300

T6920

Synonym:

Target: FGFR, c-RET, JAK, CDK, PDGFR, Src, AMPK

NG 52

T2028

Synonym: NG52,NG-52,Compound 52

Target: Chloride channel

Imipramine

T20025

Synonym: HSDB 3100,Melipramine,HSDB3100,Dimipressin,HSDB-3100

Synonym: NS 004,NS-004

Mivobulin Isethionate

T28048

Synonym: NSC-613863,CI-980,NSC-635370,NSC-613862,NSC-350386

Target:

2-fluoro Palmitic Acid

Synonym: UCD38B hydrochloride,UCD 38 B hydrochloride,UCD-38-B HCl,UCD-38-B Hydrochloride,UCD 38 B HCl

EGFRvIII peptide (PEPvIII)

TP1589

Synonym: EGFRvIII peptide PEPvIII

Pyrrolidine Ricinoleamide

T36407

Synonym:

Target:

Hematoporphyrin monomethyl ether

T38970

Synonym:

Target:

(S)-α-Methylbenzyl Ricinoleamide

Synonym: TAT-Gap19(I130A)

Target:

RAGE antagonist peptide

Pyrrolidine Linoleamide

Synonym: ENPP1 Inhibitor C

C8 Galactosylceramide (d18:1/8:0)

T36323

Synonym: C8 Galactosylceramide (d18:1/8:0)

Adenosine 5’-methylenediphosphate (hydrate)

Synonym: Leu-Ser-Leu-Iso-Thr-Arg-Leu-OH

Target:

カタログ番号	製品名	別名	ターゲット
T4S0094	Hydroxygenkwanin	Luteolin 7-methylether,7-O-Methylluteolin	Antioxidant
	1. Hydroxygenkwanin (Luteolin 7-methylether) possesses significant the antioxidative activity . 2. Hydroxygenkwanin has cytotoxicity, may be an effective natural product to treat glioma, and the combination of Apigenin a...		Antioxidant
T6S0325	Glycitein	Glycetein	Apoptosis , Others
	1. Gycitein has weak estrogenic activity. 2. Glycitein (Glycetein) inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.		Apoptosis , Others
TN2175	Salvianolic acid F		Caspase
	The role of our hybrid molecules, an analogue of Salvianolic acid F, in compelling the glioma cells towards apoptosis by specifically perturbing the concentration of glutathione along with caspase 6.		Caspase
T7131	Antineoplaston A10	NSC-648539	Apoptosis , Endogenous Metabolite , Ras
	Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.		Apoptosis , Endogenous Metabolite , Ras
TN2326	(Z)-Butylidenephthalide	(Z)-3-Butylidenephthalide	Glucosidase
	(Z)-Butylidenephthalide ((Z)-3-Butylidenephthalide) has antitumor and hypoglycemic effects, and can effectively inhibit the tumor growth of glioma and inhibit R-glucosidase activity.		Glucosidase
TN1933	Mitraphylline		IL Receptor , TNF , NF-κB
	Mitraphylline has antiproliferative effects on human glioma and neuroblastoma cell lines. It also has anti-inflammatory activity, it inhibits lipopolysaccharide-mediated activation of primary human neutrophils.		IL Receptor , TNF , NF-κB
T2945	Germacrone		P450 , Antiviral , Influenza Virus
	Germacrone, a major active component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antivirus activities. It also inhibits the proliferation of glioma cells by promoting apoptosis.		P450 , Antiviral , Influenza Virus
TN2285	DL-Tryptophan	(±)-Tryptophan,Tryptophan	Serotonin Transporter , Endogenous Metabolite
	DL-Tryptophan ((±)-Tryptophan) containing dipeptides are interesting ingredients for functional foods as a natural prevention for hypertension with reduced side effects due to its selective inhibition of the C-domain. Lo...		Serotonin Transporter , Endogenous Metabolite
TN1068	Tricin		Others , CDK
	Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7.		Others , CDK
T4928	L-Kynurenine	(S)-Kynurenine	AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
	L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has ...		AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
TN2063	Physalin B	NSC-287088	Apoptosis , NF-κB , Akt , PI3K , Nrf2 , NOD
	Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammatory eczema and herpes, among other diseases.Physalin B amel...		Apoptosis , NF-κB , Akt , PI3K , Nrf2 , NOD
T72904	Norswertianin
	Norswertianin, a xanthone-based compound, acts as a potent anti-glioma agent. It promotes differentiation of GBM cells via oxidative stress and autophagy dependent on Akt/mTOR signaling.
T21577	Narasin (sodium salt)	Naracin sodium salt,naransin sodium,HainanMycin	NF-κB
	Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells and inhibits NF-κB signaling by suppressing the phosphorylation o...		NF-κB
T10910	Cycloartenol		Others
	Cyclopentanol is a plant sterol compound and one of the key precursors for biosynthesis of various sterol compounds. Cycloartenol inhibits the migration of glioma cells and inhibits the phosphorylation of p38 MAP kinase....		Others
T82273	Gochnatiolide A
	Gochnatiolide A, a dimeric sesquiterpene isolated from Ainsliaea henryi, demonstrates antiproliferative properties against various cell lines, including kidney, melanoma, ovarian-resistant, and glioma [1] [2].
TN4838	Pseurotin A		Antifection
	Pseurotin A has immunosuppressive activity, it inhibits immunoglobulin E(IgE) production in vitro.It shows a moderate effect against the phytopathogenic bacteria Erwinia carotovora and Pseudomonas syringae, with IC50 val...		Antifection
T8199	(±)-α-Bisabolol	Bisabolol	Apoptosis , Antioxidant
	(±)-α-Bisabolol (Bisabolol) isa sesquiterpenol extracted from essential oils of chamomile, candida and other plants. It isa natural antiseptic with soothing, antiirritating, anti-inflammatory, antioxidant and anticancer ...		Apoptosis , Antioxidant

天然物製品

Hydroxygenkwanin

T4S0094

Synonym: Luteolin 7-methylether,7-O-Methylluteolin

Target: Apoptosis, Others

Target: Apoptosis, Endogenous Metabolite, Ras

(Z)-Butylidenephthalide

TN2326

Synonym: (Z)-3-Butylidenephthalide

Target: IL Receptor, TNF, NF-κB

Germacrone

T2945

Synonym:

Target: P450, Antiviral, Influenza Virus

DL-Tryptophan

TN2285

Synonym: (±)-Tryptophan,Tryptophan

Target: Serotonin Transporter, Endogenous Metabolite

Synonym: (S)-Kynurenine

Target: AhR, Aryl Hydrocarbon Receptor, Endogenous Metabolite

Physalin B

TN2063

Synonym: NSC-287088

Target: Apoptosis, NF-κB, Akt, PI3K, Nrf2, NOD

Narasin (sodium salt)

T21577

Synonym: Naracin sodium salt,naransin sodium,HainanMycin

Target: Apoptosis, Antioxidant

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01442	DMBT1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d...
TMPY-03261	CNPY2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CNPY2 is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain. CNPY2 enhances migration of C6 glioma cells through phosphorylation of the myosin regulatory light cha...
TMPK-00535	FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag)	Cynomolgus	HEK293 Cells
	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expre...
TMPK-00968	FGL2 Protein, Human, Recombinant (His & Avi, Flag)	Human	HEK293 Cells
	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expre...
TMPK-00813	FGL2 Protein, Mouse, Recombinant (His & Avi, Flag)	Mouse	HEK293 Cells
	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expre...
TMPK-00985	FGL2 Protein, Rat, Recombinant (His & Avi, Flag), Biotinylated	Rat	HEK293 Cells
	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expre...
TMPK-00970	FGL2 Protein, Human, Recombinant (hFc & Flag)	Human	HEK293 Cells
	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expre...
TMPK-00814	FGL2 Protein, Mouse, Recombinant (His & Avi, Flag), Biotinylated	Mouse	HEK293 Cells
	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expre...
TMPK-00536	FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated	Cynomolgus	HEK293 Cells
	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expre...
TMPK-00969	FGL2 Protein, Human, Recombinant (His & Avi, Flag), Biotinylated	Human	HEK293 Cells
	Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expre...
TMPK-00743	LGR-5 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	G protein-coupled receptor 5 (LGR5), known as a stem cell marker for colon cancer and gastric cancer, can serve as a novel GSC marker involved in EMT and a therapeutic target in glioma.LGR5 is a new functional GSC marker...
TMPH-03207	IL-2 Protein, Rabbit, Recombinant (His)	Rabbit	E. coli
	Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes...
TMPK-00732	WISP1/CCN4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The interplay between glioma stem cells (GSCs) and the tumor microenvironment plays crucial roles in promoting malignant growth of glioblastoma (GBM), the most lethal brain tumor. WISP1 is preferentially expressed and se...
TMPY-01843	SEMA6A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SEMA6A, the first identified class 6 semaphorin, is contributed to regulate vascular development and adult angiogenesis. SEMA6A could inhibit proliferation, migration, and invasion in different glioma cell lines. That SE...
TMPY-04817	Syntenin Protein, Human, Recombinant (His)	Human	E. coli
	Syntenin1/SDCBP (syndecan binding protein), also known as melanoma differentiation associated gene-9 (MDA-9), is a PDZ domain-containing molecule, which was initially identified as a key oncogene in melanoma. IL-6 promot...
TMPH-02442	IL-2 Protein, Rhesus macaque, Recombinant (His & Myc & SUMO)	Rhesus	E. coli
	Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes...
TMPJ-00160	EMMPRIN/CD147 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane ...
TMPJ-00546	EFNA1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can ...
TMPY-02276	GPR56 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ADGRG1 (Adhesion G Protein-Coupled Receptor G1, also known as GPR56) is a Protein Coding gene. GPR56 is a member of an adhesion G protein-coupled receptor family with a very long N-terminal stalk and seven transmembrane ...
TMPJ-00028	CCL2 Protein, Mouse, Recombinant	Mouse	E. coli
	C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence, and 58%, 56%, 55%, 53% and 53% aa identity with human, equ...
TMPY-01775	AIM2 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytopla...