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Search Results for " neurite "

ターゲット

阻害剤

天然化合物

126

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T8869	B355252		Others
	B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.		Others
T11861	LM11A-31 dihydrochloride		Others
	LM11A-31 dihydrochloride is a water-soluble, non-peptide with high blood-brain barrier permeability.LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagoni...		Others
T2306	Brexpiprazole	OPC-34712	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
	Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.		Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
T8690	Brexpiprazole HCl	OPC 34712 dihydrochloride	Others
	Brexpiprazole HCl (OPC 34712 dihydrochloride) is a new antipsychotic drug.		Others
T32658L	Leteprinim	AIT082 acid,AIT 082 acid,AIT-082 acid	Others
	Leteprinim (AIT 082 acid) is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from astrocytes.		Others
T16518	PH-002		Others
	PH-002, an inhibitor targeting the intramolecular domain interaction of apolipoprotein (apo) E4 in neuronal cells, additionally enhances mitochondrial motility and promotes neurite outgrowth, thereby countering related i...		Others
T10624	BT-13		c-RET
	BT-13 is a selective agonist of glial cell line-derived neurotrophic factor (GDNF) receptor RET independently of GFLs. BT-13 promotes neurite growth from sensory neurons in vitro.		c-RET
T9504	MAP4343		Microtubule Associated
	Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, resulting in enhanced neurite extension and protection of n...		Microtubule Associated
T15602	ITX3		Others , Rho
	ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM. ITX3 has anticancer effects, inhibits trion mediated GTP exchange on RhoG and Rac1, inhibits NGF-mediated neurite growth in P...		Others , Rho
T4431	Olodanrigan	PD-126055,EMA401	RAAS
	Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. EMA...		RAAS
T32541	Lalioside
	Lalioside is a potent accelerator of neurite outgrowth.
T29598	Acetylcarnitine arginyl amide	ST-857,acetyl-L-carnitine arginine amide
	Acetylcarnitine arginyl amide is able to stimulate neurite outgrowth in a manner similar to that elicited by nerve growth factor (NGF). Neurite induction by this molecule requires de novo mRNA synthesis and is independen...
T34778	Talaumidin
	Talaumidin is a natural neurotrophic agent which promotes neurite outgrowth from neurons through the PI3K/Akt pathway.
T0811L	Amisulpride hydrochloride	APD-421,Amisulpride HCl,APD 421,APD421,Sultopride
	Amisulpride is an antagonist of 5-HT7 receptor and dopamine D2 and D3 receptors. It modulates beta 2- arresting signaling and increases neurite outgrowth.
T33858	PACA	N-Propargyl Caffeamide
	PACA, (N-propargyl Caffeamide)enhances NGF-induced neurite growth and reduces 6-hydroxydopamine neurotoxicity in neuron cultures. Parkinson's disease (PD) is associated with insufficient production of nerve growth factor...
T26050	RC-33 HCl	RC 33 Hydrochloride,RC-33 Hydrochloride,RC33 Hydrochloride
	RC-33 HCl is a selective and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth.
T24272	KT5926	KT 5926,KT-5926
	KT5926 is an effective and selective inhibitor of myosin light chain kinase. KT5926 is an analogue of K-252a, which blocks all responses to NGF. KT5926 selectively inhibits nerve growth factor-dependent neurite elongatio...
T34706	SRI-29132	SRI29132,SRI 29132,TPZ-11,TPZ 11,TPZ11
	SRI-29132 is potent; highly permeant of the blood-brain barrier; and selective for LRRK2 kinase activity, therefore effective in attenuating pro-inflammatory responses in macrophages and in rescuing neurite retraction ph...
T26821	BIPM
	BIPM is a potent inhibitor of Rho-associated protein kinase 2 (ROCK2). Exposure of SH-SY5Y cells to BIPM led to significant changes in cell migration, actin stress fibers and neurite length. BIPM significantly inhibits p...
T75410	Ganglioside sialidase (AuSialidase S)
	Ganglioside sialidase (AuSialidase S), an endogenous metabolite, plays a critical role in neuronal differentiation, specifically in neurite outgrowth [1].
T81580	Ozanezumab	GSK1223249
	Ozanezumab (GSK1223249) is a monoclonal antibody targeting Nogo-A (neurite outgrowth inhibitor A). It is utilized in research related to amyotrophic lateral sclerosis (ALS) and multiple sclerosis [1].
T29543	ACAF4	ACAF-4,ACAF 4
	ACAF4 is a neurotrophic agent which significantly increases survival in PC12 neuronal cells and enhances the effect of nerve growth factor (NGF). ACAF4 induces neurite outgrowth, and modulates ERK1/2 and AKT signaling pa...
T37476	Cyclo(L-Phe-L-Val)
	Cyclo(L-Phe-L-Val) is a metabolite of the sponge bacterium Pseudoalteromonas sp. NJ6-3-1 that can autoinduce production of antibacterial substances active against S. aureus when co-cultured at a low cell density. It indu...
T81576	PA22-2	IKVAV sequence,Laminin A-chain fragment
	PA22-2, an active biological peptide featuring the IKVAV sequence from the laminin A-chain fragment, is derived from mouse laminin alpha1 amino acid residues 2110-2127. Substrates composed of PA22-2 have been shown to fa...
T72917	D-threo-PDMP
	D-threo-PDMP is a potent inhibitor of glucoceramide synthase (GCS), effectively reducing cell surface glycosphingolipids by inhibiting glycosylation. It also decreases the axon plexus's total length and the number of axo...
T22529	6-Bnz-cAMP sodium salt		Others
	6-Bnz-cAMP is a PKA-selective activator. It regulates the PKA dependent signaling pathways. The proliferative signaling pathway which activated by the 6-Bnz-cAMP involves activation of the epidermal growth factor recepto...		Others
T76539	Insulin-like growth factor II
	Insulin-like Growth Factor II (IGF-2), the primary somatomedin in human serum, exerts both permissive and direct influences on neurite outgrowth and significantly improves the survival of sympathetic and sensory neurons ...
T62046	HDAC6-IN-5
	HDAC6-IN-5 (compound 11b) is a potent and BBB-penetrated inhibitor of HDAC6 (IC50= 0.025 μM). HDAC6-IN-5 inhibits Aβ 1-42 self-aggregation and AChE, with IC 50s of 3.0 and 0.72 μM. HDAC6-IN-5 can enhance neurite outgrowt...
T35436	(-)-L-threo-PDMP (hydrochloride)
	(-)-L-threo-PDMP is an enhancer of ganglioside biosynthesis. The (-)-L-threo-PDMP (1S,2S) isomer is the active stimulatory component of DL-threo-PDMP in contrast to (+)-D-threo-PDMP , which is an inhibitor of glucosylcer...
T81575	PA22-2 free acid	Cys-Laminin A chain 2091-2108
	PA22-2 (free acid) (Cys-Laminin A chain 2091-2108), a peptide, promotes neurite outgrowth and facilitates the formation of neuron-like processes. It is utilized in the culturing of human adenoid cystic carcinoma cells an...
T80420	TAT-NEP1-40 acetate		Apoptosis
	TAT-NEP1-40 acetate, a potential therapeutic for axonal regeneration and functional recovery post-stroke, safeguards PC12 cells from oxygen and glucose deprivation (OGD) and encourages neurite outgrowth. This compound al...		Apoptosis
T36768	1-Octadecyl Lysophosphatidic Acid
	1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses...
T76583	H-Ile-Lys-Val-Ala-Val-OH
	H-Ile-Lys-Val-Ala-Val-OH, a significant active site within laminin-1, enhances cell adhesion, neurite outgrowth, and tumor growth. It also encourages the growth and proliferation of BMMSC populations through the activati...
T78041	Tat-peptide control 168-189 TFA
	Tat-peptide 168-189, a cell-permeable, Tat-labeled fusion peptide derived from residues 168-189 of rat G3BP1, features the HIV Tat sequence at its least conserved terminus to enhance cellular uptake. It serves as the neg...
T37283	1-Palmitoyl Lysophosphatidic Acid (sodium salt)
	1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of five different G protein-coupled receptors (GPCRs) to mediate a variety of biological...
T38213	1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))	1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))
	1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines c...
T60954	HDAC6-IN-6
	HDAC6-IN-6 (compound 6a) is a potent inhibitor of HDAC6 that can penetrate BBB with an IC50 value of 0.025 μM. HDAC6-IN-6 has potent inhibitory activity against AChE and Aβ 1-42 self-aggregation with IC50 values of 0.72 ...
T80419	TAT-NEP1-40 TFA		Apoptosis
	TAT-NEP1-40 TFA, a blood-brain barrier-permeable peptide, safeguards PC12 cells against oxygen and glucose deprivation (OGD) and fosters neurite outgrowth. Additionally, it enhances neurological outcomes post-ischemia by...		Apoptosis
T80418	TAT-NEP1-40		Apoptosis
	TAT-NEP1-40, a blood-brain barrier (BBB) permeable peptide, confers protection to PC12 cells against oxygen and glucose deprivation (OGD) while promoting neurite outgrowth. Furthermore, it enhances neurologic outcomes po...		Apoptosis
T36907	1-Oleoyl Lysophosphatidic Acid	Oleoyl-sn-3-Glycerophosphate,1-Oleoyl LPA,1-Oleoyl Lysophosphatidic Acid
	1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through ...
TP1989	NEP(1-40)	Nogo-66 (1-40)
	Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS ...

Compounds

LM11A-31 dihydrochloride

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor

Brexpiprazole HCl

T8690

Synonym: OPC 34712 dihydrochloride

Target: Others

Leteprinim

T32658L

Synonym: AIT082 acid,AIT 082 acid,AIT-082 acid

Target: Microtubule Associated

Synonym: PD-126055,EMA401

Acetylcarnitine arginyl amide

T29598

Synonym: ST-857,acetyl-L-carnitine arginine amide

Amisulpride hydrochloride

T0811L

Synonym: APD-421,Amisulpride HCl,APD 421,APD421,Sultopride

Target:

PACA

T33858

Synonym: N-Propargyl Caffeamide

Target:

RC-33 HCl

T26050

Synonym: RC 33 Hydrochloride,RC-33 Hydrochloride,RC33 Hydrochloride

Target:

KT5926

T24272

Synonym: KT 5926,KT-5926

Target:

SRI-29132

T34706

Synonym: SRI29132,SRI 29132,TPZ-11,TPZ 11,TPZ11

Ganglioside sialidase (AuSialidase S)

Synonym: ACAF-4,ACAF 4

Synonym: IKVAV sequence,Laminin A-chain fragment

6-Bnz-cAMP sodium salt

T22529

Synonym:

Target: Others

Insulin-like growth factor II

(-)-L-threo-PDMP (hydrochloride)

Synonym: Cys-Laminin A chain 2091-2108

1-Octadecyl Lysophosphatidic Acid

T36768

Synonym:

Target:

H-Ile-Lys-Val-Ala-Val-OH

T76583

Synonym:

Target:

Tat-peptide control 168-189 TFA

T78041

Synonym:

Target:

1-Palmitoyl Lysophosphatidic Acid (sodium salt)

T37283

Synonym:

Target:

1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))

T38213

Synonym: 1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))

1-Oleoyl Lysophosphatidic Acid

T36907

Synonym: Oleoyl-sn-3-Glycerophosphate,1-Oleoyl LPA,1-Oleoyl Lysophosphatidic Acid

Target:

NEP(1-40)

TP1989

Synonym: Nogo-66 (1-40)

Target:

カタログ番号	製品名	別名	ターゲット
T6S1740	Nardosinone		Others
	1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed t...		Others
TQ0218	Deoxyandrographolide	14-deoxyandrographolide	IL Receptor , TNF
			IL Receptor , TNF
T2S0843	Negletein	7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor , TNF , NOS , Interleukin
	1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...		IL Receptor , TNF , NOS , Interleukin
T3S1589	Notoginsenoside Fa		Others
	1. Notoginsenosides Fa and R4 show significant neurite outgrowth enhancing activities in human neuroblastoma SK-N-SH cells.		Others
T3836	Eudesmin		MAPK , S6 Kinase
	Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 m...		MAPK , S6 Kinase
T2S0531	Pinoresinol dimethyl ether	(+)-Eudesmin	Others , PKC
	Pinoresinol dimethyl ether, a non-phenolic furan lignan isolated from the bark of Magnolia kobus, exhibits neuroactivity. It stimulates upstream MAPK, PKC, and PKA pathways, inducing neurite outgrowth in PC12 cells.		Others , PKC
TN1038	Galgravin		Apoptosis
	Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid beta peptide (Abeta25-35)-induced cytotoxicity, and protec...		Apoptosis
TN1544	D-Menthol	Menthol,(+)-MENTHOL	Calcium Channel , 5-HT Receptor , AChR
	D-Menthol ((+)-MENTHOL) is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α±7 mediated Ca 2+ transients in the cell body and neurite, suggests that menthol...		Calcium Channel , 5-HT Receptor , AChR
T2787	Picroside I	6'-Cinnamoylcatalpol	MMP , STAT
	Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable anti-invasive drug ...		MMP , STAT
T29462	5-OH-HxMF
	5-OH-HxMF is an inducer of neurite growth in PC12 cells through the camp / PKA / CREB pathway.
TN4127	Gentiside J		Others
	Gentiside J is a potent inducer of neurite outgrowth on PC12 cells.		Others
T82444	Erinacine U
	Erinacine U, a cyanogen diterpene extracted from Hericium erinaceus, exhibits neurotrophic properties and significantly enhances neurite outgrowth in PC12 cells [1].
TN5286	3β,5α,9α-Trihydroxyergosta-7,22-dien-6-one
	3β,5α,9α-Trihydroxy-ergosta-7,22-dien-6-one in the presence of NGF (20 ng/mL) exerts a significant increase in neurite-bearing cells.
T81213	Sarbronine M
	Scabronine M, a novel inhibitor, impedes NGF-induced neurite outgrowth from PC12 cells.
TN2995	4,10-Aromadendranediol		ERK , GSK-3 , Wnt/beta-catenin
	4,10-Aromadendranediol exhibits neurite outgrowth-inducing activity in neurons via activation of the ERK signaling pathway, which may be beneficial to the treatment of brain diseases.		ERK , GSK-3 , Wnt/beta-catenin
TN2844	(2R,3S)-Dihydrodehydroconiferyl alcohol		MAPK , PKC
	(2R,3S)-Dihydrodehydroconiferyl alcohol can induce neurite outgrowth and enhance NGF-induced neurite outgrowth from PC12 cells by amplifying up-stream steps such as MAPK and PKC.		MAPK , PKC
T15702	Lactacystin		Proteasome
	Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome inhibitor (IC50: 4.8 μM for 20S proteasome). Lactacystin inhibits cell growth and induces neurite outgrowth and a...		Proteasome
TN4123	Gelsemiol		Others
	Gelsemiol has neurotrophic factor-potentiating activity, markedly enhances an increase in the proportion of neurite-bearing cells and an extension of the neurite length in the presence of nerve growth factor.		Others
TN4651	Neuchromenin		Others
	(-)-Neuchromenin is an inducer of neurite outgrowth of PC12 cells at concentration of 2.5-10 ug/ml.		Others
TN4981	Secologanin dimethyl acetal		Others
	Secologanin dimethyl acetal induces significant neurite outgrowth.		Others
TN5655	Broussonin B
	Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin B can induce neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, and show moderate inhibitory activities against a chymotrypsi...
TN4126	Gentiside B		Others
	Gentiside B is a potent inducer of neurite outgrowth on PC12 cells, it shows a significant neuritogenic activity at 30 microM against PC12 cells that is comparable to that seen for the best nerve growth factor (NGF) conc...		Others
TMA0984	Cerevisterol		DNA/RNA Synthesis
	Cerevisterol is a cytotoxic steroid, can inhibit the activity of DNA polymerase alpha. It can stimulate NGF-mediated neurite outgrowth on PC12 cells.		DNA/RNA Synthesis
T81676	NG-012
	NG-012, a nerve growth factor (NGF) potentiator, was isolated from the culture broth of Penicillium verruculosum F-4542. It enhances neurite outgrowth as induced by NGF in the rat pheochromocytoma cell line (PC12) [1].
TN4286	Isodunnianol		NOS , NF-κB , ROS , AChR
	Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0.1 to 10 uM in the primary cultured rat cortical neurons. I...		NOS , NF-κB , ROS , AChR
T81980	Kissoone C
	Kissoone C (compound 3), a sesquiterpene with a three-membered ring structure, has been isolated from valerian root. This compound has been found to promote nerve growth factor (NGF)-mediated neurite outgrowth in PC12D c...
TN2626	14-Norpseurotin A		Antifection
	14-Norpseurotin A shows good antileishmanial and moderate anticancer activities. It also displays significant antimicrobial activities against Escherichia coli, Bacillus subtilis, and Micrococcus lysoleikticus with MICs ...		Antifection
TN5682	2,6,4'-Trihydroxy-4-methoxybenzophenone
	2,6,4'-Trihydroxy-4-methoxybenzophenone shows weak inhibitory activity of testosterone 5alpha-reductase, it also shows significant inhibition of pancreatic lipase activity. 2,6,4'-Trihydroxy-4-methoxybenzophenone has neu...

天然物製品

Synonym: 14-deoxyandrographolide

Target: IL Receptor, TNF

Negletein

T2S0843

Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Target: MAPK, S6 Kinase

Pinoresinol dimethyl ether

T2S0531

Synonym: (+)-Eudesmin

Synonym: Menthol,(+)-MENTHOL

Target: Calcium Channel, 5-HT Receptor, AChR

Picroside I

T2787

Synonym: 6'-Cinnamoylcatalpol

3β,5α,9α-Trihydroxyergosta-7,22-dien-6-one

4,10-Aromadendranediol

TN2995

Synonym:

Target: ERK, GSK-3, Wnt/beta-catenin

(2R,3S)-Dihydrodehydroconiferyl alcohol

Secologanin dimethyl acetal

Target: DNA/RNA Synthesis

Target: NOS, NF-κB, ROS, AChR

2,6,4'-Trihydroxy-4-methoxybenzophenone

TN5682

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02172	Midkine Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	Midkine (MK or MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin. Midkine is a retinoic acid-responsive, h...
TMPY-00357	HNT/NTM Protein, Human, Recombinant (His)	Human	HEK293
	NTM (Neurotrimin) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylph...
TMPY-00480	NCAM1 Protein, Human, Recombinant (His)	Human	HEK293
	NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobuli...
TMPY-06985	NGF Protein, Human, Recombinant (HEK293)	Human	HEK293
	Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits,...
TMPY-02626	FGF-18 Protein, Human, Recombinant (His)	Human	HEK293
	Fibroblast growth factor 18 (FGF18) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPY-02792	GDNF Protein, Human, Recombinant (HEK293)	Human	HEK293
	Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact...
TMPY-01864	CNTF Protein, Human, Recombinant (His)	Human	E. coli
	Ciliary neurotrophic factor (CNTF) is a member of the cytokine family. It is a polypeptide hormone that has functions in promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. Its act...
TMPY-03577	Pleiotrophin/PTN Protein, Mouse, Recombinant	Mouse	Baculovirus-Insect Cells
	HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, ...
TMPY-00463	ENPP2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen...
TMPY-02778	ENPP2 Protein, Human, Recombinant (His)	Human	HEK293
	ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen...
TMPY-02632	SIRP alpha Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-01573	SIRP alpha Protein, Human, Recombinant (G75A, His)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06052	SIRP alpha V2 Protein, Human, Recombinant (His)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-05841	SIRP alpha Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06051	SIRP alpha Protein, Human, Recombinant (hFc)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-00720	Contactin 1 Protein, Human, Recombinant (His)	Human	HEK293
	Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2 (TAG-1), Contactin-3...
TMPH-02847	CNPY2 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation.
TMPH-00378	Midkine Protein, Chicken, Recombinant (His & Myc)	Chicken	E. coli
	Has mitogenic activity, and neurite extension activity for PC12 cells.
TMPH-02878	PTPRS Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects...
TMPH-01669	Metallothionein-3/MT3 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.
TMPY-02001	RTN4 Protein, Human, Recombinant (GST)	Human	E. coli
	Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that...
TMPH-01753	Netrin-4/NTN4 Protein, Human, Recombinant (GST & His & Myc)	Human	E. coli
	May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants.
TMPY-04620	Neurofascin Protein, Human, Recombinant (hFc)	Human	HEK293
	NFASC (Neurofascin, also known as NRCAML, NEDCPMD, and NF) is a Protein Coding gene. 13 alternatively spliced human isoforms have been reported. NFASC belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM famil...
TMPH-02987	PTPRS Protein, Mus musculus, Recombinant (His & Myc)	Mouse	Baculovirus
	Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects...
TMPK-00621	CSPG5 Protein, Human, Recombinant (His)	Human	HEK293
	Chondroitin sulfate proteoglycan 5 (CSPG-5), also known as neuroglycan C, has been previously associated to differentiation since it shapes neurite growth and synapse forming. CSPG-5 expression shifts in brain areas of t...
TMPY-05268	Neurofascin Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293
	NFASC (Neurofascin, also known as NRCAML, NEDCPMD, and NF) is a Protein Coding gene. 13 alternatively spliced human isoforms have been reported. NFASC belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM famil...
TMPY-03797	Neurofascin Protein, Human, Recombinant (His)	Human	HEK293
	NFASC (Neurofascin, also known as NRCAML, NEDCPMD, and NF) is a Protein Coding gene. 13 alternatively spliced human isoforms have been reported. NFASC belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM famil...
TMPH-02187	Tenascin Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown o...
TMPJ-00406	EphA8 Protein, Human, Recombinant (His)	Human	Human Cells
	EphA8, also known as Hek3 and Eek, is a 120 kDa glycosylated member of the Eph family of transmembrane receptor tyrosine kinases. The A and B classes of Eph proteins are distinguished by Ephrin ligand binding preference ...
TMPH-00001	CD133/PROM1 Protein-VLP, Human, Recombinant (His)	Human	HEK293
	May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epit...
TMPH-02842	CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epit...
TMPK-00313	Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Nectins are a small family of Ca -independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that organize intercellular junctions. They are highly homologous to the human receptor for poliovirus, and as such ha...
TMPK-00312	Nectin-1 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Nectins are a small family of Ca -independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that organize intercellular junctions. They are highly homologous to the human receptor for poliovirus, and as such ha...
TMPY-03862	TM4SF2/TSPAN7 Protein, Human, Recombinant (His)	Human	HEK293
	TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is asso...
TMPY-00029	TM4SF2/TSPAN7 Protein, Rat, Recombinant (His)	Rat	HEK293
	TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is asso...
TMPJ-00240	CAMK1 Protein, Human, Recombinant (His)	Human	Human Cells
	Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed....
TMPY-04676	MAG Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The myelin-associated glycoprotein (MAG) contains five immunoglobulin-like domains and belongs to the sialic-acid-binding subgroup of the Ig superfamily. MAG is a transmembrane glycoprotein of 100kDa localized in myelin ...
TMPY-04662	MAG Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	The myelin-associated glycoprotein (MAG) contains five immunoglobulin-like domains and belongs to the sialic-acid-binding subgroup of the Ig superfamily. MAG is a transmembrane glycoprotein of 100kDa localized in myelin ...
TMPY-03147	MAG Protein, Human, Recombinant (hFc)	Human	HEK293
	The myelin-associated glycoprotein (MAG) contains five immunoglobulin-like domains and belongs to the sialic-acid-binding subgroup of the Ig superfamily. MAG is a transmembrane glycoprotein of 100kDa localized in myelin ...
TMPY-02579	NRN1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Neuritin 1 (NRN1) is a member of the neuritin family. Neuritin is a glycosylphosphatidylinositol-anchored protein induced by neural activity. It is expressed in postmitotic-differentiating neurons of the developing nervo...
TMPJ-00692	GAS7 Protein, Human, Recombinant (His)	Human	E. coli
	Growth Arrest-Specific Protein 7 (GAS7) is expressed primarily in terminalaly differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 may play a role in neuronal development by promoting ...
TMPJ-00348	CD316 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate ...
TMPY-02569	MAG Protein, Human, Recombinant (His)	Human	HEK293
	The myelin-associated glycoprotein (MAG) contains five immunoglobulin-like domains and belongs to the sialic-acid-binding subgroup of the Ig superfamily. MAG is a transmembrane glycoprotein of 100kDa localized in myelin ...
TMPJ-01148	NRN1L Protein, Human, Recombinant (His)	Human	Human Cells
	Neuritin-like protein belongs to the neuritin family. Neuritin is a GPI-anchored protein that promotes neurite outgrowth and branching of neuritic processes in primary hippocampal and cortical cells. Neuritin expression ...
TMPY-03871	TM4SF2/TSPAN7 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is asso...
TMPY-03930	TM4SF2/TSPAN7 Protein, Cynomolgus, Recombinant (mFc)	Cynomolgus	HEK293
	TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is asso...
TMPY-03833	TM4SF2/TSPAN7 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is asso...
TMPY-03135	Contactin 3 Protein, Rat, Recombinant (His)	Rat	HEK293
	Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2 (TAG-1), Contactin-3...
TMPY-03163	Contactin 3 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2 (TAG-1), Contactin-3...
TMPY-00722	Contactin 3 Protein, Human, Recombinant (708 Asp/Asn, hFc)	Human	HEK293
	Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2 (TAG-1), Contactin-3...
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