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Others Serine Protease Influenza Virus Proteasome

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T3359	Aprotinin	Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin	Others , Serine Protease , Influenza Virus , Proteasome
	Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activat...		Others , Serine Protease , Influenza Virus , Proteasome
T76240	Urinary Trypsin Inhibitor Fragment
	Urinary Trypsin Inhibitor Fragment, a proteolytically derived segment of urinary trypsin inhibitor, demonstrates the capability to inhibit tumor cell invasion through limited proteolysis [1].
T8362	Benzamidine hydrochloride	Benzamidine HCl	Serine/threonin kinase , Serine Protease
	Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).		Serine/threonin kinase , Serine Protease
T17011	TCH-165		Proteasome
	TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs.		Proteasome
T8802	2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-	2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-fur	Serine Protease
	2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urine or synthetically produced.		Serine Protease
T73594	Chymotrypsin	Chymotrypsin A	Serine/threonin kinase
	Chymotrypsin (Chymotrypsin A) is a serine protease produced by the pancreas that cleaves protein chains on the carboxyl side of aromatic amino acids.		Serine/threonin kinase
TP2217	Alpha-1 antitrypsin fragment		Others
	Alpha-1 antitrypsin (A1AT) is known as a serum trypsin inhibitor and is a protease inhibitor belonging to the serpin superfamily. Alpha-1 antitrypsin is a single-chain glycoprotein consisting of 394 amino acids in the ma...		Others
TP2216	Alpha-1 antitrypsin fragment 235-243 [Homo sapiens]/[Papio hamadryas]/[Cercopithecus aethiops]		Others
	Protease inhibitor		Others
T76157	Chymotrypsinogen
	Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .
T9670L	Patamostat HCl	Patamostat HCl（114568-26-2 Free base）	Serine Protease , Protease
	Patamostat HCl is a highly potent and selective small molecule protease (protease) inhibitor that inhibits trypsin, fibrinolytic enzymes, and thrombin with IC50 values of 39 nM, 950 nM, and 1.9 μM, respectively.Patamosta...		Serine Protease , Protease
T6370	AEBSF hydrochloride	AEBSF HCl,Pefabloc SC	Thrombin , Serine Protease , Influenza Virus
	AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin.		Thrombin , Serine Protease , Influenza Virus
T7016	VR23		Apoptosis , Proteasome , Caspase
	VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for caspase-like proteasomes.		Apoptosis , Proteasome , Caspase
T30519	BMS-363131	BMS363131,BMS 363131	Serine Protease
	BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of <1.7 nM.		Serine Protease
T74040	Boc-Gln-Ala-Arg-AMC hydrochloride
	Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorescent compound that serves as a substrate for trypsin and is also used to determine the protein hydrolysis activity of TMPRSS2.
T6941	PI-1840	PI 1840	PARP , Proteasome
	PI-1840（IC50 = 27 nM）is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).		PARP , Proteasome
T2391	Camostat mesylate	FOY-S980,FOY305,Camostat mesilate	Serine/threonin kinase , SARS-CoV , Sodium Channel
	Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.		Serine/threonin kinase , SARS-CoV , Sodium Channel
T2122	Ixazomib	MLN2238	Proteasome , Caspase , Autophagy
	Ixazomib (MLN2238) , a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also i...		Proteasome , Caspase , Autophagy
T16169	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride	N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride	Others , Proteasome , COX
	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride (N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride) is an inhibitor of trypsin-like protease. N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride exhib...		Others , Proteasome , COX
T60248	4-Aminobenzamidine dihydrochloride	p-Aminobenzamidine dihydrochloride	Serine Protease
	4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type plasminogen activator (uPA) (K i =82 μM). 4-Aminobenzamidine can inh...		Serine Protease
T78409L	Boc-Val-Pro-Arg-MCA TFA
	Boc-Val-Pro-Arg-MCA TFA is a sensitive fluorescent substrate that is a thrombin substrate for the determination of trypsin-like serine protease activity.
TP1832	Gluten Exorphin C		Opioid Receptor
	Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.Gluten Exorphin C, isolated from the pe...		Opioid Receptor
T63321	20S Proteasome activator 1		Proteasome
	20S Proteasome activator 1 is a 20S proteasome activator with IC50 of 0.3 μM for trypsin-like sites, 0.7 μM for chymotrypsin-like sites and 1.8 μM for caspase sites. 20S Proteasome activator 1 prevents the accumulation o...		Proteasome
T25131	AZD8309	AZD 8309,AZD-8309	Glutathione Peroxidase , CXCR
	AZD8309 is a potent, orally available antagonist of the chemokine receptor CXCR2 that regulates neutrophil transport, significantly reduces MPO in the pancreas and lung, and decreases trypsin and elastase activity in the...		Glutathione Peroxidase , CXCR
T13568L	BCX 1470 hydrochloride	BCX 1470 hydrochloride(217099-43-9 Free base),BCX1470 HCl	Serine Protease , Complement System
	BCX 1470 hydrochloride is a potent serine protease inhibitor with anti-inflammatory activity that inhibits the ester hydrolysis and haemolytic activity of factor D and C1s, and can be used to study oedema.		Serine Protease , Complement System
T67959	Pirodomast		Thrombin , Serine Protease
	Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospas...		Thrombin , Serine Protease
T13568	BCX 1470		Serine Protease
	BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.		Serine Protease
T13567	BCX 1470 methanesulfonate		Serine Protease
	BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.		Serine Protease
T38521	Patamostat mesylate	E-3123 mesylate
	Patamostat mesylate (E-3123) is a highly potent protease inhibitor, displaying strong inhibitory activity against trypsin, plasmin, and thrombin, with IC 50 values of 39 nM, 950 nM, and 1.9 μM, respectively. This compoun...
T39029	APC-6860
	APC-6860 is a trypsin-like serine proteases inhibitor with k i values of 0.21, 0.44, 1.5, 16.8, 20, 30 μM for uPA, trypsin, tryptase, tPA, thrombin and factor Xa, respectively. APC-6860 has a selectivity ratio for tPA ve...
T30510	BMS-262084	BMS 262084,I0IR71971G,UNII-I0IR71971G,CHEMBL71037
	BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.
T37053	Z-(L-Arg)-AMC (hydrochloride)
	Z-(L-Arg)-AMC is a fluorogenic substrate for trypsin, cathepsin B, and cathepsin H.1,2Upon enzymatic cleavage by trypsin, cathepsin B, or cathepsin H, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can b...
T34785	TAPAP	3-Tapap
	TAPAP binds to thrombin and trypsin.
T19218	Bz-Lys-OMe		Others
	Bz-Lys-Ome is a methyl ester substrate of trypsin.		Others
T29969	AMG-126737	105RSZ5CNS,AMG 126737,SCHEMBL7986111
	AMG-126737 is an effective human lung mast cell trypsin inhibitor with potential therapeutic effect in lung diseases.
T77221	Benzenecarboximidamide, hydrochloride, hydrate (1:1:x)
	Benzenecarboximidamide, hydrochloride, hydrate (1:1:x) (Benzamidine hydrochloride hydrate) is a reversible competitive trypsin-like serine proteases inhibitor with K i s of 20, 21, 97, 110, 320 and 750 μM against Tryptas...
T19199	AzKTB		Others
	AzKTB is a capture reagent comprising an azide module linked to TAMRA/PEG-biotin labels through a short trypsin-cleavable peptide sequence.		Others
T37019	P-APMSF (hydrochloride)
	p-APMSF is an irreversible inhibitor of serine proteases with Ki values of 1.02, 1.18, 1.5, and 1.54 μM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively. It is selective for these pr...
T6564L	Leupeptin	Leupeptin Ac-LL,NK-381
	Leupeptin is a competitive protease inhibitor produced by actinomycetes. Leupeptin can inhibit cysteine, serine and threonine peptidases. Leupeptin inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), ...
T78402	Boc-Gln-Ala-Arg-AMC acetate
	Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate primarily used for assaying trypsin activity and additionally suitable for evaluating the proteolytic function of TMPRSS2[1][2].
T78409	Boc-Val-Pro-Arg-MCA hydrochloride	Boc-Val-Pro-Arg-MCA HCl
	Boc-Val-Pro-Arg-MCA hydrochloride (Boc-Val-Pro-Arg-MCA HCl) is a sensitive fluorescent substrate for the determination of trypsin-like serine proteases activity.
T19580	Thrombin (MW 37kDa)	Thrombin	Thrombin
	Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.		Thrombin
T62464	Bz-D-Arg-pNA hydrochloride
	Bz-D-Arg-pNA hydrochloride is a competitive trypsin inhibitor.
T37011	Boc-LRR-AMC
	Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is r...
T35887	MBD
	MBD, a novel fluorescent probe (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), is utilized to study the conformation of protein and nucleoprotein. Its application is extended to bacterial ribosomes, as well as b...
T72736	Aeruginosin 98-B
	Aeruginosin 98-B, a protease inhibitor, effectively inhibits trypsin, plasmin, and thrombin with IC50 values of 0.6, 7.0, and 10.0 μg/mL, respectively.
T36686	Ac-Arg-Gly-Lys(Ac)-AMC
	Ac-RGK(Ac)-AMC, fluorogenic substrate for assaying histone deacetylase (HDAC) activity in a two-step enzymatic reaction. The assay consists of the initial lysine deacetylation by HDAC followed by the release of the fluor...
T36962	MMP Inhibitor I (trifluoroacetate salt)
	MMP inhibitor I is a peptide inhibitor of matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-3 (IC50s = 1.3, 30, and 150 μM, respectively). It is selective for MMP-1, MMP-2, and MMP-3 over the proteases thermolysin, urea...
T68474	RWJ-58643 HCl
	RWJ 58643 is a reversible beta-tryptase and trypsin inhibitor. Low-dose RWJ-58643 (100 microg) and budesonide (200 microg) significantly reduced symptoms, eosinophils and levels of IL-5 following NAC. However, higher dos...
T80211	Ac-KQL-AMC
	Ac-KQL-AMC is a fluorogenic substrate designed for the quantification of Trypsin-like activity, emitting detectable fluorescence upon proteasomal cleavage [1].
T78625	Z-Ala-Arg-Arg-AMC	Z-ARR-AMC,Fluorogenic Proteasome Substrate	Proteasome
	Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) serves as a fluorogenic substrate designed to assay the trypsin-like activity within the proteasome [1].		Proteasome

Compounds

Aprotinin

T3359

Synonym: Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin

Target: Others, Serine Protease, Influenza Virus, Proteasome

Urinary Trypsin Inhibitor Fragment

T76240

Synonym:

Target:

Benzamidine hydrochloride

T8362

Synonym: Benzamidine HCl

Target: Serine/threonin kinase, Serine Protease

2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-

T8802

Synonym: 2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-fur

Target: Serine Protease

Chymotrypsin

T73594

Synonym: Chymotrypsin A

Target: Serine/threonin kinase

alpha-1 antitrypsin fragment

TP2217

Synonym:

Target: Others

alpha-1 antitrypsin fragment 235-243 [Homo sapiens]/[Papio hamadryas]/[Cercopithecus aethiops]

Synonym: Patamostat HCl（114568-26-2 Free base）

Target: Serine Protease, Protease

AEBSF hydrochloride

T6370

Synonym: AEBSF HCl,Pefabloc SC

Target: Thrombin, Serine Protease, Influenza Virus

VR23

T7016

Synonym:

Target: Apoptosis, Proteasome, Caspase

BMS-363131

T30519

Synonym: BMS363131,BMS 363131

Target: Serine Protease

Boc-Gln-Ala-Arg-AMC hydrochloride

Target: PARP, Proteasome

Camostat mesylate

T2391

Synonym: FOY-S980,FOY305,Camostat mesilate

Target: Serine/threonin kinase, SARS-CoV, Sodium Channel

Ixazomib

T2122

Synonym: MLN2238

Target: Proteasome, Caspase, Autophagy

N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride

T16169

Synonym: N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride

Target: Others, Proteasome, COX

4-Aminobenzamidine dihydrochloride

T60248

Synonym: p-Aminobenzamidine dihydrochloride

Target: Serine Protease

Boc-Val-Pro-Arg-MCA TFA

Target: Opioid Receptor

20S Proteasome activator 1

Synonym: AZD 8309,AZD-8309

Target: Glutathione Peroxidase, CXCR

BCX 1470 hydrochloride

T13568L

Synonym: BCX 1470 hydrochloride(217099-43-9 Free base),BCX1470 HCl

Target: Serine Protease, Complement System

Pirodomast

T67959

Synonym:

Target: Thrombin, Serine Protease

BCX 1470

T13568

Synonym:

Target: Serine Protease

BCX 1470 methanesulfonate

T13567

Synonym:

Target: Serine Protease

Patamostat mesylate

T38521

Synonym: E-3123 mesylate

Synonym: BMS 262084,I0IR71971G,UNII-I0IR71971G,CHEMBL71037

Target:

Z-(L-Arg)-AMC (hydrochloride)

Synonym: 105RSZ5CNS,AMG 126737,SCHEMBL7986111

Target:

Benzenecarboximidamide, hydrochloride, hydrate (1:1:x)

p-APMSF (hydrochloride)

Synonym: Leupeptin Ac-LL,NK-381

Target:

Boc-Gln-Ala-Arg-AMC acetate

T78402

Synonym:

Target:

Boc-Val-Pro-Arg-MCA hydrochloride

T78409

Synonym: Boc-Val-Pro-Arg-MCA HCl

Bz-D-Arg-pNA hydrochloride

Ac-Arg-Gly-Lys(Ac)-AMC

T36686

Synonym:

Target:

MMP Inhibitor I (trifluoroacetate salt)

Synonym: Z-ARR-AMC,Fluorogenic Proteasome Substrate

Target: Proteasome

カタログ番号	製品名	別名	ターゲット
TN6872	Trypsin		Protease-activated Receptor
	Trypsin is a serine protease that can be isolated from fish to hydrolyze lysine or arginine carboxy-side proteins. With the anti-inflammatory activity, Trypsin could induce the cell membrane fusion of PDCoV-infected cell...		Protease-activated Receptor
T5S0689	Demethylwedelolactone		Serine Protease
	Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on breast cancer cells.		Serine Protease
T16012	Marizomib	NPI-0052,Salinosporamide A,ML858	Proteasome
	Marizomib (ML858) is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L (β5), CT-T-laspase-like (C-L, β1), and trypsin-like (T-L, β2) 20S proteasomes with IC50s of 3.5, 28, and 430 nM, respectiv...		Proteasome
TN1372	Alpha-Amyrin	alpha-Amyrenol,α-Amyrin,alpha-Amyrine,Viminalol	P450 , Serine Protease , ROS
	Alpha-Amyrin (alpha-Amyrine) is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used in studies about acting as a hepatomodulatory.		P450 , Serine Protease , ROS
T2O2730	L-Serine	(S)-Serine,serine,(-)-Serine,(S)-2-Amino-3-hydroxypropanoic acid	Endogenous Metabolite
	L-Serine (serine) is a non-essential amino acid in humans, L-Serine is present and functionally important in many proteins.L-Serine is also found at the active site of the serine protease enzyme class that includes tryps...		Endogenous Metabolite
T6S0071	Fraxinellone		HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1
	1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding...		HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1
T39367	Suomilide
	Suomilide effectively inhibits human trypsin-2 and trypsin-3, displaying IC50 values of 4.7 nM and 11.5 nM, respectively. Additionally, it exhibits inhibition of trypsin-1 with an IC50 value of 104 nM.
T41033	Fetuin, Fetal Bovine Serum
	Fetuin, Fetal Bovine Serum is a glycoprotein weighing 64 kDa that is secreted by the liver and obtained from fetal bovine serum. It acts as an inhibitor of trypsin activity and facilitates cellular attachment, growth, an...
T75647	Nostosin G
	Nostosin G, a linear peptide, comprises three subunits: 4-hydroxyphenyllactic acid (Hpla), homotyrosine (Hty), and argininal. It exhibits a potent trypsin inhibitory effect, demonstrated by an IC 50 value of 0.1 μM [1].

天然物製品

Trypsin

TN6872

Synonym:

Target: Protease-activated Receptor

Demethylwedelolactone

T5S0689

Synonym:

Target: Serine Protease

Marizomib

T16012

Synonym: NPI-0052,Salinosporamide A,ML858

Target: Proteasome

Alpha-Amyrin

TN1372

Synonym: alpha-Amyrenol,α-Amyrin,alpha-Amyrine,Viminalol

Target: P450, Serine Protease, ROS

L-Serine

T2O2730

Synonym: (S)-Serine,serine,(-)-Serine,(S)-2-Amino-3-hydroxypropanoic acid

Target: Endogenous Metabolite

Fraxinellone

T6S0071

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1

Fetuin, Fetal Bovine Serum

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-00484	Cationic trypsin Protein, Canine, Recombinant (His & SUMO)	Canine	E. coli
	Cationic trypsin Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-03243	Anionic trypsin-1 Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	N/A. Anionic trypsin-1 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is P00762.
TMPH-00480	Anionic trypsin Protein, Canine, Recombinant (His & SUMO)	Canine	E. coli
	Anionic trypsin Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-03244	Anionic trypsin-2 Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	N/A. Anionic trypsin-2 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 25.3 kDa and the accession number is P00763.
TMPH-03242	Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	N/A. Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 27.2 kDa and the accession number is P00762.
TMPH-03129	Trypsin Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	P. pastoris (Yeast)
	N/A. Trypsin Protein, Pig, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 25.5 kDa and the accession number is P00761.
TMPH-03394	Trypsin-4 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	N/A. Trypsin-4 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.6 kDa and the accession number is P12788.
TMPH-03395	Trypsin-4 Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	N/A. Trypsin-4 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.1 kDa and the accession number is P12788.
TMPH-02256	Trypsin-3 Protein, Human, Recombinant (His)	Human	E. coli
	Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors.
TMPY-00198	ITIH3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ITIH3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.4 kDa and the accession number is Q06033-1.
TMPY-00397	ITIH3 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ITIH3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 97.7 kDa and the accession number is Q06033-1.
TMPH-00764	Trypsin-1 Protein, Gadus morhua, Recombinant (His)	Gadus morhua	E. coli
	Trypsin-1 Protein, Gadus morhua, Recombinant (His) is expressed in E. coli.
TMPH-02254	Trypsin-1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these subst...
TMPJ-00733	SPINK1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A dise...
TMPH-02255	Trypsin-2 Protein, Human, Recombinant (K23Q & S167G, His)	Human	E. coli
	In the ileum, may be involved in defensin processing, including DEFA5.
TMPJ-01203	HATL5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Transmembrane Protease Serine 11B (TMPRSS11B) is a single-pass type II membrane protein member of the peptidase S1 family. TMPRSS11B contains one peptidase S1 domain and one SEA domain. TMPRSS11B is a serine protease tha...
TMPH-00554	Trypsin inhibitor DE-3 Protein, Erythrina caffra, Recombinant (His)	Erythrina caffra	P. pastoris (Yeast)
	Inhibition of trypsin.
TMPY-00163	SPINK2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Human serine proteinase inhibitor Kazal-type 2 (SPINK2) functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein ...
TMPJ-00234	AMBP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Protein AMBP belongs to the calycin superfamily and Lipocalin family. AMBP can be cleaved into three chains: α-1-microglobulin, inter-α-trypsin inhibitor light chain and trypstatin. AMBP is expressed by the liver and sec...
TMPY-02480	Chymotrypsin C Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Chymotrypsin C (abbreviated for CTRC), also known as caldecrin or elastase4, is a digestive enzyme of the peptidase S1 family. This enzyme is synthesized as an inactivate chymotrypsinogen. On cleavage by trypsin into two...
TMPH-01770	Neurotrypsin Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. Neurotrypsin Protein, Human, Recombinant (His & SUMO) is expressed in...
TMPY-01897	PRSS3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on...
TMPJ-01204	TPSAB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T...
TMPY-01104	Coagulation factor XI/F11 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p...
TMPY-01580	PRSS2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists...
TMPH-02897	SPINK1 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.; In the male reproductive tract, binds to sperm heads where it modulat...
TMPH-00119	Conglutin-7 Protein, Arachis hypogaea, Recombinant (His)	Arachis hypogaea	E. coli
	Weak inhibitor of trypsin. Conglutin-7 Protein, Arachis hypogaea, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.0 kDa and the accession number is Q6PSU...
TMPH-02643	Enteropeptidase Protein, Mouse, Recombinant (His & Myc)	Mouse	HEK293 Cells
	Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes in...
TMPH-02644	Enteropeptidase Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes in...
TMPH-03370	Serpin A3K Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Binds to and inhibits kallikreins. Inhibits trypsin but not chymotrypsin or elastase. Serpin A3K Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted ...
TMPH-00661	Ecotin Protein, E. coli O127:H6, Recombinant (His & Myc)	E. coli	E. coli
	General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
TMPH-02895	Serpin A3K Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Contrapsin inhibits trypsin-like proteases. Serpin A3K Protein, Mouse, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 45.7 kDa and the accession number is P07759.
TMPH-02408	SPI Protein, Lentinula edodes, Recombinant (His)	Lentinula edodes	E. coli
	Serine protease inhibitor. Active against beta-trypsin and alpha-chymotrypsin with dissociation constants of 0.35 nM and 40 nM respectively. Inhibits factor XIa, but not other enzymes involved in coagulation and fibrinol...
TMPH-02455	Acrosin Protein, Meleagris gallopavo, Recombinant (His & Myc)	Meleagris gallopavo	E. coli
	Serine protease of trypsin-like cleavage specificity. Synthesized in a zymogen form, proacrosin and stored in the acrosome. Acrosin Protein, Meleagris gallopavo, Recombinant (His & Myc) is expressed in E. coli expression...
TMPY-04626	Enterokinase/EK Protein, Bovine, Recombinant	Bovine	P. pastoris (Yeast)
	Enterokinase is a member of the trypsin family of serine proteases. The precursor protein is cleaved into two chains which then forms a heterodimer linked by a disulfide bond. The heavy chain anchors enterokinase in the ...
TMPJ-01320	BSSP-4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial c...
TMPJ-01069	Serpin A1e Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-...
TMPJ-00481	CELA3A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Chymotrypsin-Like Elastase Family Member 3A (CELA3A) is an enzyme that contains one peptidase S1 domain. ELA3A belongs to the peptidase S1 family of the Elastase subfamily. ELA3A is secreted from the pancreas as a zymoge...
TMPH-02898	SPINK2 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defe...
TMPJ-00542	TPSB2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites faci...
TMPH-03106	Coagulation factor XII Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	E. coli
	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, whic...
TMPJ-01282	Serpin B12 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular f...
TMPY-01718	Serpin B12 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPJ-01083	Serpin E2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice lea...
TMPJ-00505	Serpin A1 Protein, Human, Recombinant (aa 25-418, His)	Human	HEK293 Cells
	Serpin A1 is a prototype member of the Serpin superfamily of the serine protease inhibitors. As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in hepatocytes, and to a lesser extent,...
TMPJ-00796	Serpin E2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal panc...
TMPY-02117	Marapsin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasi...
TMPY-00867	Kallikrein 13/KLK13 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene res...