| T2876 |
Flavone
|
2-Phenyl-4-benzopyron,2-Phenyl-4-chromone,2-Phenylchromone |
NOS
,
Endogenous Metabolite
|
|
Flavone (2-Phenyl-4-chromone) have effects on CYP (P450) activity which are enzymes that metabolize most drugs in the body. |
| TN6187 |
3,5,8,3'-Tetramethoxy-6,7,4',5'-bis(methylenedioxy)flavone
|
|
|
|
3,5,8,3'-Tetramethoxy-6,7,4',5'-bis(methylenedioxy)flavone is a natural product for research related to life sciences. The catalog number is TN6187 and the CAS number is 82668-93-7. |
| T83303 |
5,7,8-Trihydroxy-6-methoxy flavone-7-O-glucuronideb
|
|
|
|
5,7,8-Trihydroxy-6-methoxyflavone-7-O-glucuronide is a naturally occurring compound extractable from Scutellaria baicalensis Georgi [1]. |
| T2755 |
Rhoifolin
|
Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside |
Others
,
p38 MAPK
,
NF-κB
,
transporter
,
IGF-1R
,
Autophagy
|
|
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves. |
| TN7053 |
3',4',7-Trimethoxyquercetin
|
3,5-Dihydroxy-7,3',4'-trimethoxyflavone,Quercetin 3′,4′,7-trimethyl ether |
Others
|
|
3',4',7-Trimethoxyquercetin (3,5-Dihydroxy-7,3',4'-trimethoxyflavone) is a polymethoxyquercetin isolated from Scutellaria baicalensis with antioxidant activity. |
| T2816 |
7,8-Dihydroxyflavone
|
7,8-DHF |
Apoptosis
,
Trk receptor
|
|
7,8-Dihydroxyflavone (7,8-DHF) is a naturally-occurring flavone and exist in Tridax procumbens, Godmania aesculifolia, and primula tree leaves. |
| T2940 |
6-Hydroxyflavone
|
6-HF |
GABA Receptor
|
|
6-Hydroxyflavone (6-HF) is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It is reported in leaves of Barleria prionitis Linn. (a common Acanthaceae from India). 6-Hydro... |
| T8260 |
4',5-Dihydroxyflavone
|
|
Lipoxygenase
,
Glucosidase
|
|
4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM). |
| T8036 |
6-Methylflavone
|
|
GABA Receptor
|
|
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. |
| T2O2744 |
Alpha-Naphthoflavone
|
7,8-benzoflavone |
Aromatase
|
|
alpha-Naphthoflavone (7,8-benzoflavone), a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM. |
| TN1863 |
Licoisoflavone A
|
Phaseoluteone |
MRP
|
|
Licoisoflavone A (Phaseoluteone) is an MRP inhibitor and inhibits lipid peroxidation with an IC50 of 7.2 μM. |
| TN3016 |
4',6,7-Trimethoxyisoflavone
|
|
MMP
|
|
4',6,7-Trimethoxyisoflavone promotes wound healing through NOX2 induction, which leads to collective migration and MMP activation. |
| TN3175 |
6-Methoxyflavone
|
|
Others
|
|
6-Methoxyflavone is one of the methoxyflavone isolated form Pimelea decora. Synthesis of 6-methoxyflavone from p-dihydroxybenzene has been reported. |
| T3329 |
4',7-Dimethoxyisoflavone
|
Dimethoxydaidzein,Daidzein dimethyl ether |
Endogenous Metabolite
,
Antifungal
|
|
4',7-Dimethoxyisoflavone (Daidzein dimethyl ether) , a kind of isoflavonoids, showed inhibitory effects on rat prostate testosterone 5α-reductase. |
| T7327 |
7-Methoxyisoflavone
|
|
AMPK
|
|
7-Methoxyisoflavone is an activator of adenosine monophosphate-activated protein kinase (AMPK). |
| T4S0181 |
Hinokiflavone
|
|
MMP
,
BCL
,
E1/E2/E3 Enzyme
|
|
Hinokiflavone, a novel modulator of pre-mRNA splicing activity both in vitro and in cellulo, inhibits the assembly of the spliceosome, particularly blocking the formation of the B complex. Additionally, it acts as a SUMO... |
| T8296 |
5,7,4'-Trimethoxyflavone
|
4',5,7-Trimethoxyflavone |
Apoptosis
,
PARP
,
Caspase
|
|
5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand. |
| T7472 |
7-Hydroxyflavone
|
|
P450
|
|
7-Hydroxyflavone is a potent inhibitor of CYP1A1 with a Ki value of 0.015 μM and exhibits 6-fold greater selectivity for CYP1A1 over CYP1A2.with anti-inflammatory activity |
| T7982 |
3,6-Dihydroxyflavone
|
|
Others
|
|
3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway. |
| T5778 |
5,7-DIMETHOXYFLAVONE
|
|
Anti-infection
,
P450
|
|
5,7-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential. |
| TN1860 |
Licoflavone B
|
|
ATPase
,
Anti-infection
,
Parasite
|
|
Licoflavone B has schistosomicidal activity, it showed high S. mansoni ATPase (IC50 of 23.78 μM) and ADPase (IC50 of 31.50 μM) inhibitory activities. |
| T8268 |
6,2'-Dihydroxyflavone
|
|
GABA Receptor
|
|
6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor. |
| TN1287 |
5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavone
|
5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavone |
Others
|
|
5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavone is a natural product from Artemisia argyi. |
| TN3091 |
5,7-Diacetoxy-8-methoxyflavone
|
ZINC77031696 |
PDE
|
|
5,7-Diacetoxy-8-methoxyflavone is derived from the roots of Scutellaria baicalensis and inhibits cAMP phosphodiesterase. |
| TN3847 |
Dihydroalpinumisoflavone
|
|
|
|
Dihydroalpinumisoflavone is a natural product derived from the leaves and stems of Crotalaria madurensis. |
| T8194L |
Soy Isoflavone
|
|
Others
|
|
Soy Isoflavone is extracted from the seeds of leguminous plants. The isoflavones in soybeans are natural phytoestrogens, which have good medicinal value and can reduce the incidence of breast cancer in women, relieve men... |
| TN1859 |
Licoflavone A
|
|
Phosphatase
|
|
Licoflavone A is a natural product isolated from the roots of Glycyrrhiza uralensis. |
| T8180 |
7-Hydroxyisoflavone
|
|
Others
|
|
7-Hydroxyisoflavone against Enterovirus 71 in vitro. |
| TN2143 |
3,7,4'-Trihydroxyflavone
|
Resokaempferol,5-Deoxykampferol |
DNA
|
|
3,7,4'-Trihydroxyflavone(5-Deoxykampferol) is a DNA-breaking flavonoid isolated from rosewood heartwood. It inhibits osteoclast differentiation, actin ring formation, and bone resorption in RAW 264.7 cells and bone marro... |
| T8246 |
4'-METHOXYFLAVONE
|
|
Others
|
|
4'-METHOXYFLAVONE is a natural product. |
| T7994 |
3-Methoxyflavone
|
|
Antiviral
|
|
3-Methoxyflavone is a Flavonoids, with antiviral activity |
| TN1236 |
3',4',7-Trihydroxyisoflavone
|
|
MAPK
,
JNK
|
|
3',4',7-Trihydroxyisoflavone is a soy isoflavone soy glycoside derivative and Cot (Tpl2/MAP3K8) and MKK4 inhibitor with anticancer, antiangiogenic and free radical scavenging properties.3',4',7-Trihydroxyisoflavone enhan... |
| T8229 |
5,7,3',4'-Tetramethoxyflavone
|
|
Antibacterial
,
Parasite
,
Antifungal
|
|
5,7,3',4'-Tetramethoxyflavone (TMF), a prominent polymethoxyflavone (PMF) derived from M. exotica, displays a range of notable bioactivities. These include anti-malarial, anti-fungal, anti-mycobacterial, and anti-inflamm... |
| T6S0139 |
Neobavaisoflavone
|
|
Apoptosis
,
DNA/RNA Synthesis
|
|
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si... |
| TN3209 |
3′,4′,7-Trihydroxyflavone
|
|
ATPase
,
Others
,
p38 MAPK
,
NF-κB
|
|
3'4'7-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand (RANKL) induced osteoclastic differentiation from mouse bone marrow derived macrophages (BMMs), it inhibits osteoclasto... |
| TN2943 |
3-Hydroxy-6-methoxyflavone
|
|
Others
|
|
3-Hydroxy-6-methoxyflavone can be used in combination with antibiotics to treat ESKAPE pathogen infections. |
| T8245 |
3,4-Dihydroxyflavone
|
|
Others
|
|
3,4-Dihydroxyflavone Acts as an Antioxidant and Antiapoptotic Agent . |
| T2A2486 |
3',4',5',5,7-Pentamethoxyflavone
|
5,7,3',4',5'-Pentamethoxyflavone |
Nrf2
|
|
3',4',5',5,7-Pentamethoxyflavone is a naturally occurring brassinosteroid compound from the Rutaceae family that exhibits resistance to cancer cells by inhibiting the Nrf2 pathway to overcome chemotherapeutically active ... |
| TQ0134 |
Podocarpusflavone A
|
|
Topoisomerase
,
STAT
|
|
Podocarpusflavone A is a DNA topoisomerase I and STAT3 inhibitor, a flavonoid chemically inactive isolated from the endemic Taiwanese plant, Luo Han Guo, with potential antileishmanial activity and antitumor activity.Pod... |
| TN2121 |
3,5,7,3′,4′-Pentamethoxyflavone
|
Quercetin 3,5,7,3,4-pentamethyl ether |
Others
|
|
3,5,7,3′,4′-Pentamethoxyflavone (Quercetin 3,5,7,3,4-pentamethyl ether) is a natural product. It can induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation. |
| TN2773 |
2'-Methoxyflavone
|
|
Others
|
|
2'-Methoxyflavone is a bioactive chemical. |
| T2P2963 |
5-Methyl-7-methoxyisoflavone
|
|
Others
|
|
1. 5-Methyl-7-methoxyisoflavone is used by bodybuilders for its ergogenic properties. |
| T5779 |
MOSLOFLAVONE
|
|
IL Receptor
,
Virus Protease
,
TNF
,
Antibacterial
|
|
MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively. |
| T7051 |
5,6,7-TRIMETHOXYFLAVONE
|
Baicalein Trimethyl Ether |
p38 MAPK
|
|
5,6,7-Trimethoxyflavone, a natural product extracted from Japanese Callicarpa, acts as a p38-α MAPK inhibitor and exhibits anti-inflammatory properties. |
| T8263 |
3,4'-Dihydroxyflavone
|
|
Influenza Virus
|
|
3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid. 3,4'-Dihydroxyflavone (3,4'-DHF) shows antiviral activity against Influenza A virus. |
| TN1088 |
3,5,6,7,8,3',4'-Heptemthoxyflavone
|
3,3',4',5,6,7,8-heptamethoxyflavone |
Others
|
|
3,5,6,7,8,3',4'-Heptemthoxyflavone has neuroprotective, chemopreventive, anti-allergic, anti-inflammatory, immunomodulatory, anti-aging and photoprotective effects; it inhibits collagenase activity and induces type I pro... |
| T8248 |
3,7-DIHYDROXYFLAVONE
|
|
Others
|
|
3,7-DIHYDROXYFLAVONE is a natural product extracted from the herbs of Atraphaxis pyrifolia |
| TN3396 |
Alpinumisoflavone acetate
|
4'-O-Acetylalpinumisoflavone |
Others
|
|
Alpinumisoflavone acetate (4'-O-Acetylalpinumisoflavone) is a new alpinumisoflavone derivative. Alpinumisoflavone strongly inhibits germ tube growth at 0.63 ug/disc. |
| TN1995 |
5,7,8-Trimethoxyflavone
|
Norwogonin 5,7,8-trimethyl ether |
NO Synthase
|
|
5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether) is a compound extracted from Andrographis paniculata with anti-inflammatory activity and NO inhibition. |
| TN1861 |
Licoflavone C
|
4',5,7-Trihydroxy-8-prenylflavone |
Antioxidant
,
Antifungal
|
|
Licoflavone C (4',5,7-Trihydroxy-8-prenylflavone) is an isoprenoid-based flavonoid compound isolated from the roots of Glycyrrhiza inflata, which possesses antioxidant and antifungal activities, and is known to have a pr... |
