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Search Results for " Glucosidase "

ターゲット

Glucosidase Glucosidase

107

阻害剤

110

天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T67898	α-Glucosidase-IN-22		Glucosidase
	α-Glucosidase-IN-22 is a selective inhibitor of α-glucosidase (IC50=0.64 μM). α-Glucosidase-IN-22 has antidiabetic activity and has potential in type 2 diabetes (T2DM) studies.		Glucosidase
T67728	α-Glucosidase-IN-23		Glucosidase
	α-Glucosidase-IN-23 is an orally active α-Glucosidase inhibitor. α-Glucosidase-IN-23 can decrease blood glucose by α-glucosidase inhibition (IC50= 4.48 μM).		Glucosidase
T41028	α-Glucosidase	α-D-Glucosidase
	α-Glucosidase (α-D-Glucosidase) is a carbohydrate hydrolyzing enzyme that catalyzes the release of α-glucose from the non-reducing end of the substrate. It plays a vital role in facilitating glucose absorption by the sma...
T60715	α-Glucosidase-IN-4		Glucosidase
	α-Glucosidase-IN-4 is a potent α-glucosidase inhibitor with antihypertensive and hypoglycemic activity.		Glucosidase
T76110	β-Glucosidase
	β-Glucosidase, a pivotal enzyme in cellulose degradation, belongs to the extensive family of glycoside hydrolases. It plays a crucial role in breaking down cellulose in soils and holds promise for assessing biological so...
T63562	α-Glucosidase-IN-14
	α-Glucosidase-IN-14 is a potent inhibitor of α-glucosidase (IC50: 5.22 μM).
T62222	α-Glucosidase-IN-11
	α-Glucosidase-IN-11 is a highly permeable competitive inhibitor of α-glucosidase (IC50: 0.56 μM). α-Glucosidase-IN-11 binds to the Trp residue in α-glucosidase and has a regulatory effect on protein folding and can be us...
T61519	α-Glucosidase-IN-18
	α-Glucosidase-IN-18 (7B) is an orally active inhibitor of α-glucosidase, displaying an IC 50 value of 3.96 μM. This compound exhibits antidiabetic properties [1].
T61166	α-Glucosidase-IN-16
	α-Glucosidase-IN-16 is a highly effective and orally bioavailable inhibitor of α-glucosidase, displaying a remarkable IC50 value of 3.28 μM. This compound demonstrates the ability to significantly decrease blood glucose ...
T61124	α-Glucosidase-IN-9
	α-Glucosidase-IN-9 (compound 7) is a highly potent α-glucosidase inhibitor with an IC50 of 55.6 μM, making it suitable for type II diabetes research [1].
T60389	α-Glucosidase-IN-5
	α-Glucosidase-IN-5 (compound 8) is isolated from a twig extract of Polyalthia cinnamomea which is a potent α-glucosidase inhibitor with an IC50 of 57.9 µM. α-Glucosidase-IN-5 has the potential for the research of diabete...
T78794	α-Glucosidase-IN-31		Glucosidase
	α-Glucosidase-IN-31 (compound R1) is a potent oral α-Glucosidase inhibitor with an IC50 of 10.1 μM, demonstrating significant blood glucose reduction and antidiabetic activity [1].		Glucosidase
T79237	α-Glucosidase-IN-27		Glucosidase
	α-Glucosidase-IN-27 (compound 8l), an α-glucosidase inhibitor with an IC50 value of 25.78 μM, demonstrates potential for research into type 2 diabetes (D2M) [1].		Glucosidase
T79700	α-Glucosidase-IN-32		Glucosidase
	α-Glucosidase-IN-32 (compound f26) is a reversible, noncompetitive inhibitor of α-glucosidase that is orally active and exhibits an IC50 of 3.07 μM. It forms a complex with α-glucosidase via hydrogen bonding and hydropho...		Glucosidase
T80709	α-Glucosidase-IN-41		Glucosidase
	α-Glucosidase-IN-41 (compound 5o), a potent inhibitor of α-glucosidase, induces alterations in the secondary structure of the enzyme, thereby impeding its catalytic function. This compound is utilized in the study of dia...		Glucosidase
T78740	α-Glucosidase-IN-28		Glucosidase
	α-Glucosidase-IN-28 (Compound 18) is an α-glucosidase inhibitor with an IC50 of 0.62 μM and Ki value of 3.93 μM. It interacts with the enzyme's original binding site (OBS) and establishes multiple hydrophobic interaction...		Glucosidase
T63310	α-Glucosidase-IN-6
	α-Glucosidase-IN-6 is a competitive inhibitor of α-glucosidase (IC50: 5.69 μM) and exhibits potential for anti-diabetic studies.
T61503	α-Glucosidase-IN-15
	α-Glucosidase-IN-15 (Compound 14B) exhibits potent inhibitory activity against α-glucosidase, with an IC50 value of 3.34 μM. It possesses antidiabetic properties [1].
T62972	α-Glucosidase-IN-17
	α-Glucosidase-IN-17 (Compound 12B) is a potent and orally active inhibitor of α-glucosidase, demonstrating antidiabetic activity with an inhibitory concentration (IC50) of 3.79 μM [1].
T80711	α-Glucosidase-IN-39		Glucosidase
	α-Glucosidase-IN-39 is a potent α-glucosidase enzyme inhibitor, exhibiting an IC50 value of 869.06 ppm. It is applicable for use in antidiabetic studies [1].		Glucosidase
T61761	α-Glucosidase-IN-21
	α-Glucosidase-IN-21 (Compound 2B) is a highly potent and orally bioavailable inhibitor of α-glucosidase. With an impressive IC50 value of 2.62 μM, this compound exhibits remarkable anti-diabetic properties [1].
T61331	α-Glucosidase-IN-20
	α-Glucosidase-IN-20 (Compound 3B) is a highly effective and orally active inhibitor of α-glucosidase. It exhibits potent anti-diabetic properties, as evidenced by its IC50 value of 3.01 μM [1].
T78864	α-Glucosidase-IN-33		Glucosidase
	α-Glucosidase-IN-33 (compound 7c), with an IC50 of 2.39 μM, is a potent inhibitor of α-glucosidase and is relevant in research on type 2 diabetes and hyperglycemia [1].		Glucosidase
T78865	α-Glucosidase-IN-34		Glucosidase
	α-Glucosidase-IN-34 (compound 7f) is a potent inhibitor of α-glucosidase, exhibiting an IC50 of 2.90 μM, and is applicable in research related to type 2 diabetes and hyperglycemia [1].		Glucosidase
T80708	α-Glucosidase-IN-42		Glucosidase
	α-Glucosidase-IN-42 (Compound 26), a 9-O-berberrubine carboxylate derivative, exhibits potent α-glucosidase inhibitory activity with an IC50 value of 1.61 μM and has potential for use in antidiabetic research [1].		Glucosidase
T78741	α-Glucosidase-IN-29		Glucosidase
	α-Glucosidase-IN-29 (compound 19) is an inhibitor of α-glucosidases, exhibiting an IC50 value of 1.21 μM and a Ki of 1.80 μM. This compound is utilized in the research of diabetes and related diseases [1].		Glucosidase
T63361	α-Glucosidase-IN-13
	α-Glucosidase-IN-13 is an inhibitor of α-glucosidase (IC50: 5.69 μM).
T62994	α-Glucosidase-IN-10
	α-Glucosidase-IN-10 (compound 13) is a potent inhibitor of α-glucosidase (IC50: 92.7 μM). α-Glucosidase-IN-10 can be used to study type II diabetes.
T63574	α-Glucosidase-IN-12
	α-Glucosidase-IN-12 is a potent inhibitor of α-glucosidase (IC50: 10.20 μM).
T61249	α-Glucosidase-IN-2
	α-Glucosidase-IN-2 (compound 5d) is a potent inhibitor of α-Glucosidase, exhibiting an inhibitory concentration (IC50) of 9.48 μM, and functions as an antidiabetic agent [1].
T62891	α-Glucosidase-IN-19
	Alpha-Glucosidase-IN-19 (Compound 6B) is an orally active alpha-glucosidase inhibitor (IC50: 3.63 μM) with antidiabetic effects.
T61094	α-Glucosidase-IN-8
	α-Glucosidase-IN-8 (Compound 4k) is a potent, competitive inhibitor of α-glucosidase. It displays an impressive IC50 value of 0.18 μg/mL [1].
T64230	α-Glucosidase-IN-3
	α-Glucosidase-IN-3 is an oleanolic acid oxime ester derivative targeting α-glucosidase and α-amylase with an IC50 value of 0.35 μM for α-glucosidase.
T80710	α-Glucosidase-IN-40		Glucosidase
	α-Glucosidase-IN-40 (compound 5) serves as a noncompetitive inhibitor of the α-glucosidase enzyme, exhibiting an inhibitory concentration (IC50) of 24.62 μM [1].		Glucosidase
T80712	α-Glucosidase-IN-38		Glucosidase
	α-Glucosidase-IN-38 (Compound 11j) is a potent α-glucosidase inhibitor, demonstrating an IC50 of 12.44±0.38 μM, and is significant in the context of Diabetes mellitus (DM) management [1].		Glucosidase
T78731	α-Glucosidase-IN-26		Glucosidase
	α-Glucosidase-IN-26 (Compound 7i), with an IC50 value of 4.63 µM, functions as an α-glucosidase inhibitor and is utilized in research related to type 2 diabetes mellitus (T2DM) [1].		Glucosidase
T79259	α-Glucosidase-IN-25		Glucosidase
	α-Glucosidase-IN-25 (Compound (R)-8k) serves as a competitive inhibitor for α-glucosidase, demonstrating an inhibitory concentration 50 (IC50) of 1.19μM, making it applicable in anti-diabetic research [1].		Glucosidase
T78881	α-Glucosidase-IN-36		Glucosidase
	α-Glucosidase-IN-36 (compound 5g) is a potent inhibitor of α-glucosidase, exhibiting an IC50 value of 6.69 ± 0.18 μM and inhibition constants Ki and Kis of 1.65 μM and 4.54 μM, respectively. It is hypothesized to suppres...		Glucosidase
T79318	α-Glucosidase-IN-30		Glucosidase
	α-Glucosidase-IN-30 (compound 8c) is a potent, orally active competitive inhibitor of α-glucosidase, exhibiting a K i of 40.0 µM and an IC50 of 49.0 µM. It is non-cytotoxic to both cancerous MCF-7 and normal HDF cell lin...		Glucosidase
T61706	α-Amylase/α-Glucosidase-IN-2
	α-Amylase/α-Glucosidase-IN-2 (compound 5) exhibits strong inhibition activity towards both α-amylase and α-glucosidase enzymes, with IC 50 values of 13.02 μM and 13.09 μM, respectively. This compound shows promise for in...
T79225	α-Amylase/α-Glucosidase-IN-3		Glucosidase
	α-Amylase/α-Glucosidase-IN-3 (Compound 17) serves as a dual inhibitor targeting both α-Amylase and α-Glucosidase, exhibiting IC50 values of 0.70 μM and 1.10 μM, respectively. It is applicable for type-II diabetes mellitu...		Glucosidase
T60255	α-Amylase/α-Glucosidase-IN-1
	α-Amylase/α-Glucosidase-IN-1 (compound 33) is an effective inhibitor of α-amylase/α-glucosidase with IC 50 s of 2.01, 2.09 μM for α-amylase and α-glucosidase, respectively. Kinetic studies predict that α-Amylase/α-Glucos...
T79402	α-Amylase/α-Glucosidase-IN-4		Glucosidase
	α-Amylase/α-Glucosidase-IN-4 (compound 5), a dual inhibitor targeting α-amylase (Amylases) and α-glucosidase (Glucosidase), exhibits potent inhibition with IC50 values of 1.10 μM and 0.15 μM respectively. This compound i...		Glucosidase
T80715	α-Amylase/α-Glucosidase-IN-6
	α-Amylase/α-Glucosidase-IN-6 (compound 5j) serves as a potent dual inhibitor of both α-amylase and α-glucosidase, exhibiting IC50 values of 17.0 µM and 40.1 µM, respectively. It demonstrates anti-hyperglycemic activities...
T78878	α-Amylase/α-Glucosidase-IN-5		Glucosidase
	α-Amylase/α-Glucosidase-IN-5 (compound 4l) functions as a dual inhibitor, effectively inhibiting both α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC50 values of 5.96 μM and 1.62 μM, respectively, exhibiting...		Glucosidase
TQ0300	Conduritol B epoxide		Glucosidase
	Conduritol B epoxide is an irreversible inhibitor of β-glucosidase (GCase).		Glucosidase
T8989	NCGC 607	NCGC607	Others
	NCGC 607 is a a noninhibitory chaperone of glucocerebrosidase (GCase).		Others
T8986	ML198		Glucokinase
	ML198 is a novel activator and non-inhibitory chaperone of glucocerebrosidase. ML198 serves as a starting point to develop a novel approach towards small molecule treatment for patients suffering from Gaucher disease.		Glucokinase
T4280	Gcase activator 1	LTI-291,LTI 291,LTI291	Glucosidase
	Gcase activator 1 (LTI-291) is a glucocerebrosidase (Gcase) activator.		Glucosidase
T0920	Ambroxol	Ambroxolum,NA-872	P450 , Autophagy
	Ambroxol (NA-872) is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a muco...		P450 , Autophagy

Compounds

α-Glucosidase-IN-22

T67898

Synonym:

Target: Glucosidase

α-Glucosidase-IN-23

T67728

Synonym:

Target: Glucosidase

α-Glucosidase

T41028

Synonym: α-D-Glucosidase

Target: Glucosidase

α-Glucosidase-IN-14

T63562

Synonym:

Target:

α-Glucosidase-IN-11

T62222

Synonym:

Target:

α-Glucosidase-IN-18

T61519

Synonym:

Target:

α-Glucosidase-IN-16

α-Glucosidase-IN-31

T78794

Synonym:

Target: Glucosidase

α-Glucosidase-IN-27

T79237

Synonym:

Target: Glucosidase

α-Glucosidase-IN-32

T79700

Synonym:

Target: Glucosidase

α-Glucosidase-IN-41

T80709

Synonym:

Target: Glucosidase

α-Glucosidase-IN-28

T78740

Synonym:

Target: Glucosidase

α-Glucosidase-IN-15

T61503

Synonym:

Target:

α-Glucosidase-IN-17

T62972

Synonym:

Target:

α-Glucosidase-IN-39

T80711

Synonym:

Target: Glucosidase

α-Glucosidase-IN-21

T61761

Synonym:

Target:

α-Glucosidase-IN-20

T61331

Synonym:

Target:

α-Glucosidase-IN-33

T78864

Synonym:

Target: Glucosidase

α-Glucosidase-IN-34

T78865

Synonym:

Target: Glucosidase

α-Glucosidase-IN-42

T80708

Synonym:

Target: Glucosidase

α-Glucosidase-IN-29

T78741

Synonym:

Target: Glucosidase

α-Glucosidase-IN-13

T63361

Synonym:

Target:

α-Glucosidase-IN-10

T62994

Synonym:

Target:

α-Glucosidase-IN-12

α-Glucosidase-IN-19

α-Glucosidase-IN-40

T80710

Synonym:

Target: Glucosidase

α-Glucosidase-IN-38

T80712

Synonym:

Target: Glucosidase

α-Glucosidase-IN-26

T78731

Synonym:

Target: Glucosidase

α-Glucosidase-IN-25

T79259

Synonym:

Target: Glucosidase

α-Glucosidase-IN-36

T78881

Synonym:

Target: Glucosidase

α-Glucosidase-IN-30

T79318

Synonym:

Target: Glucosidase

α-Amylase/α-Glucosidase-IN-2

T61706

Synonym:

Target:

α-Amylase/α-Glucosidase-IN-3

T79225

Synonym:

Target: Glucosidase

α-Amylase/α-Glucosidase-IN-1

T60255

Synonym:

Target:

α-Amylase/α-Glucosidase-IN-4

T79402

Synonym:

Target: Glucosidase

α-Amylase/α-Glucosidase-IN-6

T80715

Synonym:

Target:

α-Amylase/α-Glucosidase-IN-5

T78878

Synonym:

Target: Glucosidase

Conduritol B epoxide

TQ0300

Synonym:

Target: Glucosidase

Synonym: LTI-291,LTI 291,LTI291

Target: Glucosidase

Ambroxol

T0920

Synonym: Ambroxolum,NA-872

Target: P450, Autophagy

カタログ番号	製品名	別名	ターゲット
T3S0860	Gitogenin		UGT
	1. Gitogenin, tigogenin, and solasodine are novel selective inhibitors of UGT1A4, and do not inhibit the activities of major human CYP isoforms. 2. Gitogenin and (25S)-5α-furastan-3β, 22, 26-triol are the inhibitors of e...		UGT
T75612	α-Glucosidase-IN-24
	α-Glucosidase-IN-24 (Compound 13), an α-Glucosidase inhibitor, exhibits an IC50 value of 451 μM and can be derived from Swertia kouitchensis [1].
T80713	α-Glucosidase-IN-37
	α-Glucosidase-IN-37 (Compound 11) moderately inhibits lipopolysaccharide (LPS)-induced nitric oxide (NO) production in macrophages, exhibiting an inhibitory concentration 50 (IC50) value of 23.7 μM. Additionally, this co...
T13130	Terphenyllin		Glucosidase
	Terphenyllin has α-glucosidase inhibitory activity, and is a natural product isolated from the coral derived fungus Aspergillus candidus.		Glucosidase
TN6771	Malabaricone B		Others
	Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.		Others
T7544	Fucoidan		Others
	Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.		Others
TN1990	Norathyriol		Akt , DNA/RNA Synthesis , AMPK , PPAR
	Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.		Akt , DNA/RNA Synthesis , AMPK , PPAR
TN1451	Brevifolincarboxylic acid		AhR , Aryl Hydrocarbon Receptor , Glucosidase
	Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarboxylic acid is an α-glucosidase inhibitor with an IC50 of 3...		AhR , Aryl Hydrocarbon Receptor , Glucosidase
T8319	Butyl isobutyl phthalate	ButylIsobutylPhthalate	Glucosidase
	Butyl isobutyl phthalate (ButylIsobutylPhthalate) is a non-competitive α-glucosidase inhibitor(IC50 :38 μM),it shows a hypoglycemic effect		Glucosidase
T12142	N-Caffeoyl O-methyltyramine		Glucosidase
	N-Caffeoyl O-methyltyramine is isolated from Cuscuta reflexa with strong inhibitory activity against α-glucosidase with IC50 of 103.58 μM.		Glucosidase
T41044	Naringinase		Glucosidase
	Naringinase is a hydrolytic enzymatic complex that exhibits α-L-rhamnosidase and β-D-glucosidase activities. It is widely found in nature and is primarily utilized for the biotransformation of steroids, antibiotics, and ...		Glucosidase
T8260	4',5-Dihydroxyflavone		Lipoxygenase , Glucosidase
	4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).		Lipoxygenase , Glucosidase
T7028	Licochalcone C	LICOCHALCONEC	Phosphatase , Antioxidant , Glucosidase
	Licochalcone C (LICOCHALCONEC) has potent antioxidant properties and inhibition of bacterial growth and cellular respiration. It has cardioprotection effect, via antioxidant, anti-inflammatory, and anti-apoptotic activit...		Phosphatase , Antioxidant , Glucosidase
TN2030	P-Hydroxyphenethyl trans-ferulate		5-HT Receptor
	P-Hydroxyphenethyl trans-ferulate exhibits affinity toward 5-HT(7) receptors in a competitive binding assay. P-Hydroxyphenethyl trans-ferulate can double quinone reductase specific activity in Hepa 1c1c7 cells at a level...		5-HT Receptor
T0247	Acarbose	BAY g 5421	Glucosidase
	Acarbose (BAY g 5421) is an inhibitor of α-Glucosidases with antihyperglycemic activity.		Glucosidase
T2956	Cedryl acetate	Cedrol acetate,Cedranyl acetate	Antifungal
	Cedryl acetate (Cedranyl acetate) , an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions.		Antifungal
T6723	Voglibose	AO 128,Glustat,Basen	Glucosidase
	Voglibose (Glustat), an N-substituted derivative of valiolamine, exhibits excellent inhibitory activity against α-glucosidases and action against hyperglycemia and various disorders caused by hyperglycemia.		Glucosidase
T8202	Kaempferol 3-O-gentiobioside	Kaempferol 3-gentiobioside	Glucosidase
	Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. It possesses activity against α-glucosidase and displays a carbohydrate enzyme inhibitory effect (IC50: 50 μM).		Glucosidase
TN2144	Resveratroloside		P450 , NO Synthase
	Resveratroloside has cardioprotective effect, it exhibits α±-glucosidase inhibitory activity, it also can inhibit hydroxylation of testosterone by CYP3A4.		P450 , NO Synthase
T2S1158	4,5-Dicaffeoylquinic acid	3,4-Dicaffeoylquinic acid,Isochlorogenic acid C	Others , HBV , Endogenous Metabolite
	1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity.		Others , HBV , Endogenous Metabolite
TN1926	Methyl caffeate	Methyl caffeate acid	Others , Antibacterial
	Methyl caffeate (Methyl caffeate acid) acid		Others , Antibacterial
T5S0788	Oroxin A	Baicalein 7-O-glucoside	PPAR
	Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.		PPAR
TQ0308	Castanospermine	1,6,7,8-Tetrahydroxyoctahydroindolizine,(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine	Glucosidase
	Castanospermine (1,6,7,8-Tetrahydroxyoctahydroindolizine) is a natural compound that inhibits α- and β-glucosidases, especially glucosidase l.		Glucosidase
T3675	1-Deoxynojirimycin	Duvoglustat,Moranoline,moranolin	PI3K , Glucosidase
	1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.		PI3K , Glucosidase
T6S1525	3,4-Dicaffeoylquinic acid	Isochlorogenic acid B	Apoptosis , Antioxidant , Influenza Virus , Endogenous Metabolite
	3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.
T3235	Rebaudioside A	Reb-A 97,Reb A,Stevioside A3,Glycoside A3	Endogenous Metabolite , Glucosidase
	Rebaudioside A (Reb A) is a novel agent of glycoside clathration of pharmacons, acts as α-glucosidase inhibitor.		Endogenous Metabolite , Glucosidase
T21344	1-Deoxynojirimycin hydrochloride	Moranoline,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin	PI3K , Antibacterial , Antibiotic , Glucosidase
	1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia.		PI3K , Antibacterial , Antibiotic , Glucosidase
TN6784	Ethyl rosmarinate	Methyl rosmarinate	MMP , Tyrosinase , Glucosidase
	Methyl rosmarinate (Methyl rosmarinate) inhibit the activity of tyrosinase, α-glucosidase, and matrix metalloproteinase-1 (MMP-1).		MMP , Tyrosinase , Glucosidase
TN2326	(Z)-Butylidenephthalide	(Z)-3-Butylidenephthalide	Glucosidase
	(Z)-Butylidenephthalide ((Z)-3-Butylidenephthalide) has antitumor and hypoglycemic effects, and can effectively inhibit the tumor growth of glioma and inhibit R-glucosidase activity.		Glucosidase
TN1487	Chrysin 6-C-arabinoside 8-C-glucoside		Others
	Chrysin 6-C-arabinoside 8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.		Others
TN1488	Chrysin 6-C-glucoside 8-C-arabinoside		Others
	Chrysin 6-C-glucoside 8-C-arabinoside and Chrysin-6-C-arabinosyl-8-C-glucoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.		Others
T3S2072	3-Butylidenephthalide	Butylidene phthalide,n-Butylidenephthalide	Parasite , Glucosidase
	1. 3-Butylidenephthalide (Butylidene phthalide) has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitiv...		Parasite , Glucosidase
TL0009	Coniferin	Coniferoside,Abietin	Others , Antifungal
	Coniferin (Abietin) has ATP-dependent transport activity and has anti-oxidation effects. Coniferin has preferred substrates for the coniferin beta-glucosidase, the chromogenic coniferin analogue show the exclusive presen...		Others , Antifungal
T1529	Miglitol	BAY1099,BAY-m1099	Others
	Miglitol (BAY1099) is an alpha-Glucosidase Inhibitor with antihyperglycemic activity.		Others
TN7134	Magnoloside B		Glucosidase
	Magnoloside B, a phenylethanol glycoside from the fruit of Magnolia officinalis, is an α-glucosidase inhibitor with protective effects against free radical-induced oxidative damage and can be used in cancer research.		Glucosidase
T6S2122	Ginkgolic Acid (C13:0)	6-Tridecylsalicylic acid,Ginkgolic acid (13:0),Ginkgoneolic Acid,Ginkgolic acid C13:0	Antibacterial , Glucosidase
	Ginkgolic Acid (C13:0) (6-Tridecylsalicylic acid): 0exhibits the highest α-glucosidase inhibitory activity.		Antibacterial , Glucosidase
TN2302	Viscidulin III	Ganhuangenin	Glucosidase
	Viscidulin III (Ganhuangenin) is present in Scutellaria baicalensis and acts as an α-glucosidase inhibitor.		Glucosidase
TN1705	Glycyrrhisoflavone		MAO , Tyrosinase , NO Synthase , Immunology/Inflammation related
	Glycyrrhisoflavone is a tyrosinase inhibitor with anti-inflammatory effects. Glycyrrhisoflavone inhibits α-glucosidase and monoamine oxidase.
TN1928	Methyl rosmarinate		MMP , Anti-infection , Tyrosinase
	Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase.Methyl rosmarinate shows antioxidative, and antifungal activities. It has...		MMP , Anti-infection , Tyrosinase
T6S0535	Pinoresinol diglucoside	Pinoresinol Diglucopyranoside	Glucosidase
	1. Pinoresinol diglucoside (Pinoresinol Diglucopyranoside) is a putative α-glucosidase inhibiting compound. 2. Pinoresinol diglucoside is a important antihypertensive compound.		Glucosidase
TN2277	Torachrysone-8-O-b-D-glucoside	Torachrysone 8-O-glucoside	Antifection
	Torachrysone-8-O-b-D-glucoside shows alpha-glucosidase inhibitory activities, it may be used for the management of type 2 diabetes.		Antifection
T6S1371	Isovitexin	Homovitexin,Saponaretin,Apigenin-6-C-Glucoside	NF-κB , JNK , Glucosidase
	1. Isovitexin (Apigenin-6-C-Glucoside) exhibits a potential antioxidant activity. 2. Isovitexin shows a strong antihyperglycemic action, inhibits α-glucosidase in vivo.		NF-κB , JNK , Glucosidase
TN2130	Manghaslin	Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside	AChE , Glucosidase
	Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. Manghaslin also shows inhibito...		AChE , Glucosidase
T3796	Betulinaldehyde	Betulinic aldehyde,Betulinal,Betunal	Apoptosis , Antibacterial
	Betulinaldehyde (Betunal) has the inhibition of Saccharomyces sp and alpha-glucosidase. Betulinaldehyde induces apoptosis in mouse B16 2F2 cells. Betulinaldehyde has anti-proliferative activity against mouse +SA mammary ...		Apoptosis , Antibacterial
T5293	Maltotriose	D-Maltotriose,Amylotriose	Others , Endogenous Metabolite
	Maltotriose (Amylotriose) is a common oligosaccharide metabolite found in human urine after maltose ingestion or infusion. Maltotriose is increased in Glycogen storage disease II due to a mutation of the enzyme alpha-1,4...		Others , Endogenous Metabolite
T5690	7,4'-Di-O-methylapigenin	4',7-DIMETHOXY-5-HYDROXYFLAVONE	Amylase
	7,4'-Di-O-methylapigenin (4',7-DIMETHOXY-5-HYDROXYFLAVONE) can inhibit α-glucosidase and α-amylase enzymes and enhance 2-NBDG uptake in L6 cells, it has hypolipidemic effect on mouse pre-adipocyte (3T3L1) cell lines.		Amylase
TN1956	Mulberrofuran G		Phosphatase , HBV , Glucosidase
	Mulberrofuran G, isolated from Morus alba L., has anti-hepatitis B virus activity and protects against ischemic injury-induced cell death. Mulberrofuran G is a dual inhibitor of PTP1B and alpha-glucosidase for use in the...		Phosphatase , HBV , Glucosidase
TN4368	Kaempferol-3,7-di-O-β-glucoside	Kaempferol 3,7-di-O-glucoside	Glucosidase , Amylase
	Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) is a flavonol from Morettia philaena, It can inhibit α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3, 7-di-o-β-Glucoside has neuroprotective ac...		Glucosidase , Amylase
T5S1988	Isorhamnetin-3-O-glucoside	Isorhamnetin-3-O-beta-D-Glucoside	Others
	Isorhamnetin-3-O-glucoside (Isorhamnetin-3-O-beta-D-Glucoside) inhibits the activity of alpha-glucosidase from rat intestine; it exhibits a potent rat lens aldose reductase (RLAR) inhibition in vitro, its IC(50) being 1....		Others
TN3500	Beta-Amyrone	β-Amyron	COX , AChR , PPAR , Antifection
	beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits a...		COX , AChR , PPAR , Antifection
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天然物製品

α-Glucosidase-IN-24

T75612

Synonym:

Target:

α-Glucosidase-IN-37

Target: Glucosidase

Target: Akt, DNA/RNA Synthesis, AMPK, PPAR

Brevifolincarboxylic acid

TN1451

Synonym:

Target: AhR, Aryl Hydrocarbon Receptor, Glucosidase

Butyl isobutyl phthalate

T8319

Synonym: ButylIsobutylPhthalate

Target: Glucosidase

N-Caffeoyl O-methyltyramine

T12142

Synonym:

Target: Glucosidase

Naringinase

T41044

Synonym:

Target: Glucosidase

4',5-Dihydroxyflavone

T8260

Synonym:

Target: Lipoxygenase, Glucosidase

Licochalcone C

T7028

Synonym: LICOCHALCONEC

Target: Phosphatase, Antioxidant, Glucosidase

P-Hydroxyphenethyl trans-ferulate

TN2030

Synonym:

Target: 5-HT Receptor

Acarbose

T0247

Synonym: BAY g 5421

Target: Glucosidase

Cedryl acetate

T2956

Synonym: Cedrol acetate,Cedranyl acetate

Target: Antifungal

Voglibose

T6723

Synonym: AO 128,Glustat,Basen

Target: Glucosidase

Kaempferol 3-O-gentiobioside

T8202

Synonym: Kaempferol 3-gentiobioside

Target: Glucosidase

Resveratroloside

TN2144

Synonym:

Target: P450, NO Synthase

4,5-Dicaffeoylquinic acid

T2S1158

Synonym: 3,4-Dicaffeoylquinic acid,Isochlorogenic acid C

Target: Others, HBV, Endogenous Metabolite

Methyl caffeate

TN1926

Synonym: Methyl caffeate acid

Target: Others, Antibacterial

Oroxin A

T5S0788

Synonym: Baicalein 7-O-glucoside

Target: PPAR

Castanospermine

TQ0308

Synonym: 1,6,7,8-Tetrahydroxyoctahydroindolizine,(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine

Target: Glucosidase

1-Deoxynojirimycin

T3675

Synonym: Duvoglustat,Moranoline,moranolin

Target: PI3K, Glucosidase

3,4-Dicaffeoylquinic acid

T6S1525

Synonym: Isochlorogenic acid B

Target: Apoptosis, Antioxidant, Influenza Virus, Endogenous Metabolite

Rebaudioside A

T3235

Synonym: Reb-A 97,Reb A,Stevioside A3,Glycoside A3

Target: Endogenous Metabolite, Glucosidase

1-Deoxynojirimycin hydrochloride

T21344

Synonym: Moranoline,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin

Target: PI3K, Antibacterial, Antibiotic, Glucosidase

ethyl rosmarinate

TN6784

Synonym: Methyl rosmarinate

Target: MMP, Tyrosinase, Glucosidase

(Z)-Butylidenephthalide

TN2326

Synonym: (Z)-3-Butylidenephthalide

Target: Glucosidase

Chrysin 6-C-arabinoside 8-C-glucoside

TN1487

Synonym:

Target: Others

Chrysin 6-C-glucoside 8-C-arabinoside

TN1488

Synonym:

Target: Others

3-Butylidenephthalide

T3S2072

Synonym: Butylidene phthalide,n-Butylidenephthalide

Target: Parasite, Glucosidase

coniferin

TL0009

Synonym: Coniferoside,Abietin

Target: Others, Antifungal

Miglitol

T1529

Synonym: BAY1099,BAY-m1099

Target: Glucosidase

Ginkgolic Acid (C13:0)

T6S2122

Synonym: 6-Tridecylsalicylic acid,Ginkgolic acid (13:0),Ginkgoneolic Acid,Ginkgolic acid C13:0

Target: Antibacterial, Glucosidase

Viscidulin III

TN2302

Synonym: Ganhuangenin

Target: Glucosidase

Glycyrrhisoflavone

TN1705

Synonym:

Target: MAO, Tyrosinase, NO Synthase, Immunology/Inflammation related

Methyl rosmarinate

TN1928

Synonym:

Target: MMP, Anti-infection, Tyrosinase

Pinoresinol diglucoside

T6S0535

Synonym: Pinoresinol Diglucopyranoside

Target: Glucosidase

Torachrysone-8-O-b-D-glucoside

TN2277

Synonym: Torachrysone 8-O-glucoside

Target: Antifection

Isovitexin

T6S1371

Synonym: Homovitexin,Saponaretin,Apigenin-6-C-Glucoside

Target: NF-κB, JNK, Glucosidase

Manghaslin

TN2130

Synonym: Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside

Target: AChE, Glucosidase

Betulinaldehyde

T3796

Synonym: Betulinic aldehyde,Betulinal,Betunal

Target: Apoptosis, Antibacterial

Maltotriose

T5293

Synonym: D-Maltotriose,Amylotriose

Target: Others, Endogenous Metabolite

7,4'-Di-O-methylapigenin

T5690

Synonym: 4',7-DIMETHOXY-5-HYDROXYFLAVONE

Target: Phosphatase, HBV, Glucosidase

Kaempferol-3,7-di-O-β-glucoside

TN4368

Synonym: Kaempferol 3,7-di-O-glucoside

Target: Glucosidase, Amylase

Isorhamnetin-3-O-glucoside

T5S1988

Synonym: Isorhamnetin-3-O-beta-D-Glucoside

Target: COX, AChR, PPAR, Antifection

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-05099	GBA/glucocerebrosidase Protein, Human, Recombinant (His)	Human	HEK293
	Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramida...
TMPY-01579	GBA3 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glyc...
TMPH-03484	Agn1 Protein, S. pombe, Recombinant (His & Myc)	Fission yeast	E. coli
	Has a role in cell separation where it is required for the degradation of the cell wall material surrounding the septum (the septum edging) which must be hydrolyzed before full separation of the daughter cells can occur....

GBA/glucocerebrosidase Protein, Human, Recombinant (His)

TMPY-05099

Species: Human

Expression System: HEK293

GBA3 Protein, Human, Recombinant (His)

TMPY-01579

Species: Human

Expression System: Baculovirus-Insect Cells

Agn1 Protein, S. pombe, Recombinant (His & Myc)

TMPH-03484

Species: Fission yeast

Expression System: E. coli

カタログ番号	製品名
L7100	Anti-Obesity Compound Library		2247 compounds
	A unique collection of 2247 anti-obesity compounds for high throughput and high content screening;

ライブラリー

Anti-Obesity Compound Library

L7100

Compounds: 2247