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カタログ番号 | 製品名 | 別名 | ターゲット |
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T2320 | Indacaterol | Adrenergic Receptor | |
Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist. | |||
T4330 | CaCCinh-A01 | Chloride channel | |
CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM). | |||
T15108 | DG-041 | Prostaglandin Receptor | |
DG-041 is an antagonist of high-affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively). DG-041 inhibits PGE2 facilitation of platelet aggregation and has the blood-brain barrier per... | |||
T3461 | Losartan Carboxylic Acid | EXP-3174,E-3174 | RAAS |
Losartan Carboxylic Acid (E-3174) a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. Losartan Carboxylic Acid , a metabolite of losartan, is more potent than l... | |||
T15418 | GS-6201 | CVT-6883 | Adenosine Receptor |
GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors with a Ki of 22 nM. | |||
T5329 | Trandolapril | Angiotensin-converting Enzyme (ACE) | |
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat. | |||
T1479 | Isosorbide dinitrate | Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate | Others , NO Synthase |
Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris. | |||
T1239 | Indacaterol maleate | QAB149 | Adrenergic Receptor |
Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist. | |||
T7714 | Temocapil | Tyrosinase | |
Temocapril is an inhibitor of tyrosine kinase. | |||
T3230 | NLRP3-IN-2 | 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,NLRP3 Inflammasome Inhibitor I | NOD-like Receptor (NLR) , NOD |
NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting i... | |||
T6698 | Temocapril hydrochloride | CS-622 HCl,Acecol,Temocapril HCl,CS-622 | RAAS |
Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension. | |||
T21821L | REV 5901A | REV 5901 HCl,REV 5901A(101910-24-1 Free base) | Leukotriene Receptor , Lipoxygenase , Antibiotic |
REV 5901A (REV 5901 HCl) is an orally active leukotriene receptor antagonist and 5-lipoxygenase inhibitor with antimicrobial activity that attenuates colon cancer growth in mice.REV 5901A has been used in studies of asth... | |||
T67941 | PDE5-IN-9 | ||
PDE5-IN-9 inhibits Phosphodiesterase PDE1c and is used to treat hypertension, heart failure, myocardial infarction, kidney failure, asthma, bronchitis, and dementia. | |||
T16286 | Nelonemdaz | Salfaprodil free base,Neu2000 | Antioxidant , NMDAR |
Nelonemdaz (Neu2000) is an NMDA receptor antagonist with antioxidant activity and neuroprotective activity used in the study of cerebral infarction reperfusion injury and acute ischemic stroke. | |||
T24115 | GSK854 | GSK-854,GSK 854 | Apoptosis |
GSK854 is a highly selective and potent inhibitor of troponin I interacting kinase (TNNI3K) that inhibits myocardial infarction-injured cellular pyroptosis and apoptosis in mice, which may limit oxidative stress, injury,... | |||
T11239 | Ethacizine hydrochloride | NIK-244,Ethacizin,NIK-244 hydrochloride | Sodium Channel |
Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity, and its effects are related to cardiac activity and can be used to study arrhythmias and myocardial infarction. | |||
T68022L | Sulotroban potassium | BM 13177 potassium,Sulotroban potassium(72131-33-0 Free base) | PPAR |
Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis. | |||
T0407 | Edaravone | MCI-186 | Apoptosis , MMP , Free radical scavengers |
Edaravone (MCI-186)(MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction. | |||
T64084 | Clazosentan | ||
Clazosentan (Ro 61-1790) is a selective antagonist of the endothelin A receptor (ETAreceptor) and exhibits an inhibitory effect on ET-1-mediated vasoconstriction.Clazosentan prevents cerebral vasospasm and vasospasm-asso... | |||
T83977 | BIIB 722 Mesylate | Sodium Channel | |
BIIB 722 Mesylate is a selective sodium-hydrogen exchange inhibitor with cardioprotective properties and can be used to study myocardial ischemia and myocardial infarction. | |||
T77611 | DAPK-IN-2 | WAY-380496 | DAPK |
DAPK-IN-2 (WAY-380496) is a DAPK inhibitor. DAPK-IN-2 has potential anticancer activity, regulates autophagy and can be used to study cerebral infarction and ischemic diseases. | |||
T12078 | ML334 | LH601A | Nrf2 |
TP2279L | Obestatin (rat) acetate | GHSR | |
Obestatin (rat) acetate is an endogenous ligand of G-protein coupled receptor 39 (GPR39). Obestatin (rat) acetate has anti-inflammatory, anti-myocardial infarction and antioxidant properties. Obestatin (rat) acetate supp... | |||
T0230 | Prasugrel | LY640315,CS-747,PCR 4099 | P2Y Receptor |
Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME; UNSTABLE ANGINA and MYOCARDIAL INFARCTION, as well as in those... | |||
T39115 | ABR-238901 | TLR | |
ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products) and TLR4 (toll-like receptor 4). ABR-238901 has potential a... | |||
T22323 | Enoxaparin sodium | Thrombin | |
Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percu... | |||
T36569 | KR-32568 | Sodium Channel | |
KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM). KR-32568 exhibits potent cardioprotective effects. When used at a concentration of 10 μM, it restored cardiac systolic function in an isolated i... | |||
T24873 | TGX-115 | TGX 115 | PI3K |
TGX-115 is a cell-permeable and potent inhibitor of the PI 3-K isoform p110β/p110δ (IC50 values of 0.13 μM for p110β and 0.63 μM for p110δ), an enzyme that regulates platelet adhesion and inhibits phosphoinositide (PI) 3... | |||
T31206 | Darexaban | YM 150,Darexaban, Tanexaban,YM150 | Factor Xa |
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formati... | |||
T14390L | (2R,3S)-Azelaprag | Apelin receptor | |
(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM.(2R,3S)-N-(4-(... | |||
T27581 | Icrocaptide | ITF 1697,ITF-1697,ITF1697 | |
Icrocaptide is used potentially for the treatment of acute myocardial infarction. | |||
T28130 | Naltiazem | RO 236152,RO-236152,RO236152 | |
Naltiazem, a calcium channel antagonist, is used potentially for the treatment of arrhythmias, hypertension and myocardial infarction. | |||
T21206 | Triphenyltetrazolium bromide | AI3-62388 | |
Triphenyltetrazolium bromide may be used to detect experimental cerebral infarction and biochemical analysis. | |||
T24746 | Zalunfiban | RUC4,RUC 4,RUC-4 | |
RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction. | |||
T34327 | Ridogrel | R-70416,R 68070,R-68070,R70416,R 70416,R68070 | |
Lidogrell is a dual-acting agent that can be used to prevent systemic thromboembolism and as an adjunct to thrombolytic therapy in acute myocardial infarction. | |||
T69078 | Tiapamil Free Base | ||
Tiapamil Free Base is a phenylethylamine derivative that acts as a calcium antagonist showing hemodynamic effects in patients with acute myocardial infarction. | |||
T22685 | CP-471474 | CP 471474 | Others |
Broad spectrum MMP inhibitor (IC<sub>50</sub> values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Attenuates early left ventricular dilation after experimental myocardial infa... | |||
T37697 | D-GsMTx4 | D-GsMTx4 | |
TRPC1/6 and Piezo2 inhibitor. Exhibits same effect as L-enantiomer, GsMTx4 (Cat. No. 4912) on TRPC channels. Inhibits mechanosensitive currents by ~70%. Protects against myocardial infarction in mouse ischemia/reperfusi... | |||
T73240 | PDE5-IN-4 | ||
PDE5-IN-4, a phosphodiesterase 5 (PDE5) inhibitor, is utilized in research concerning acute myocardial infarction and reperfusion-related damage, gastrointestinal diseases, diabetic complications, and liver failure. | |||
T69000 | Prenalterol hydrochloride | ||
Prenalterol hydrochloride is a partial adrenergic agonist with functional beta 1-receptor specificity and inotropic effect. It is effective in the treatment of acute cardiac failure, postmyocardial infarction low-output ... | |||
T77026 | Goflikicept | ||
Goflikicept (RPH 104), a hybrid protein, selectively targets and neutralizes circulating IL-1ß and IL-1α. This compound shows promise for the investigation of ST-segment elevation myocardial infarction (STEMI) [1]. | |||
T11740L | Delcasertib acetate | KAI-9803,KID1-1,CS-9803,BMS-875944,Delcasertib acetate(949100-39-4 free base) | PKC |
Delcasertib acetate is a selective δ protein kinase C (δPKC) inhibitor for the study of acute myocardial infarction and pain. | |||
T77166 | Rovelizumab | ||
Rovelizumab, a humanized monoclonal leukointegrin antibody, targets CD11/CD18 cell adhesion proteins. It has potential applications in the research of multiple sclerosis (MS), hemorrhagic shock, myocardial infarction (MI... | |||
T61540 | F15845 | ||
F 15845 is a potent and persistent blocker of the sodium current. It possesses cardioprotective properties and exhibits both anti-ischemic activity and short- and long-term cardioprotection following myocardial infarctio... | |||
T71800 | Metoprolol HCl | ||
Metoprolol is a selective β1 receptor blocker medication. It is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate. It is... | |||
T78026 | LQVTDSGLYRCVIYHPP TFA | ||
LQVTDSGLYRCVIYHPP (LP17) TFA is a TREM-1 (triggering receptor expressed on myeloid cells) inhibitory peptide that notably mitigates ischemic infarction and neuronal damage. This compound is capable of penetrating the bra... | |||
T11448 | GOAT-IN-1 | Others | |
T62878 | Zalunfiban dihydrochloride | ||
Zalunfiban (RUC-4) dihydrochloride is a selective and potent platelet αIIbβ3 antagonist with an IC50 value of 45 nM. Zalunfiban dihydrochloride can be used to study myocardial infarction. | |||
T38800 | MMPI-1154 | ||
MMPI-1154 is a highly promising imidazole-carboxylic acid (ICA) MMP-2 inhibitor (IC 50 = 6.6 μM) with excellent cardio-cytoprotective properties. It is specifically designed for the study of acute myocardial infarction. ... | |||
T62507 | Protease-Activated Receptor-1 antagonist 1 | ||
Protease-Activated Receptor-1 antagonist 1 (Compound 13) is a protease-activated receptor 1 (PAR-1) antagonist with an IC50 of 3 nM obtained by the FLIPR technique. antagonist 1 can be used to study thrombotic cardiovasc... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T2893 | Muscone | 3-Methylcyclopentadecanone,Methylexaltone | MMP , TNF , NF-κB , NOD-like Receptor (NLR) , P-gp , Interleukin |
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk. | |||
T3S0289 | Araloside X | Calcium Channel | |
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane perox... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-00545 | Dermcidin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely dia... | |||
TMPY-00369 | LY6D Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of... | |||
TMPK-01229 | IL-19 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Interleukin-19 (IL-19) has been shown to be involved in coronary artery diseases and atherosclerosis, while its expression in myocardial infarction is poorly understood. In this study, the dynamic increase in circulating... | |||
TMPY-03756 | BBOX1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
BBOX1, also known as gamma-BBH, belongs to thegamma-BBH/TMLD family. It is highly expressed in kidney and moderately expressed in liver. BBOX1 catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last ste... | |||
TMPJ-00753 | Myoglobin Protein, Human, Recombinant (His) | Human | E. coli |
Myoglobin(MB) is a cytoplasmic protein expressed in myocytes of the heart and skeletal muscle that reversibly binds oxygen. It belongs to the globin family. Functions of myoglobin include oxygen storage and transport, as... | |||
TMPY-01481 | FLAP Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP), also known as FLAP, belongs to the MAPEG family. ALOX5AP/FLAP is an essential partner of 5-LO for this process. The FLAP (ALOX5AP) gene has been linked to risk fo... | |||
TMPJ-00402 | CD117 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to ... | |||
TMPJ-00091 | G-CSF Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis ... | |||
TMPJ-00785 | FABP3 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is in... | |||
TMPY-04387 | AKT2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
AKT (AK mouse plus Transforming or Thymoma) is a frequent oncogene expressed in most tissues which includes three isoforms AKT1, AKT2, and AKT3. Hyperactivation of AKT signaling is a central key in many human cancer prog... | |||
TMPJ-00952 | CXCL12 Protein, Mouse, Recombinant | Mouse | E. coli |
Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs including brain, kidney, skeletal muscle, heart, liver, an... |
カタログ番号 | 製品名 | ||
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L2910 | Antioxidant Compound Library | 1314 compounds | |
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ... |