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Search Results for " integrin "

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155

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
TP1484L	α2β1 Integrin Ligand Peptide acetate	α2β1 Integrin Ligand Peptide acetate (134580-64-6)	Integrin
	α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor. α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the...		Integrin
T13473	αvβ1 integrin-IN-1		Integrin
	αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.		Integrin
T36291	Integrin modulator 1
	Integrin modulator 1 is a potent and selective α4β1 integrin agonist, with an IC50 of 9.8 nM for RGD-binding α4β1. Integrin modulator 1 increases cell adhesion mediated by α4β1 integrin, with an EC50 of 12.9 nM[1]. Integ...
T40361	Integrin Binding Peptide
	Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.
T40243	αvβ5 integrin-IN-1
	αvβ5 integrin-IN-1, a potent and selective αvβ5 integrin inhibitor, exhibits a high inhibitory potency with a pIC50 value of 8.2.
T15584	Integrin Antagonists 27		Others
	Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.		Others
T11663	Integrin-IN-2		Others
			Others
TP1484	α2β1 Integrin Ligand Peptide
	The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen recep...
T13473L	αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)	αvβ1 integrin-IN-1 TFA	Integrin
	αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).		Integrin
TP1374	α2β1 Integrin Ligand Peptide TFA
	α2β1 Integrin Ligand Peptide TFA interacts with the integrin receptor on the cell membrane and enters the cell to mediate extracellular signaling.It is a potential antagonist of the collagen receptor.
T79140	αvβ6 integrin inhibitor 2		Integrin
	αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.		Integrin
T82063	Integrin signaling inhibitor, mP13
	Integrin Signaling Inhibitor mP13 is a compound that impedes both inside-out and outside-in integrin-mediated signaling processes, such as fibrinogen binding, platelet adhesion, and clot retraction [1].
T79792	αvβ1 integrin-IN-2		Integrin
	αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively. Additionally, this compound inhibits a range of other integrins, with IC50 valu...		Integrin
T79918	α7β1 integrin modulator-1		Integrin
	α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].		Integrin
T63868	α5β1 integrin agonist-1
	α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.
T12177	Natalizumab		Integrin
	Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.		Integrin
T16695	Pyrintegrin		Integrin
	Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...		Integrin
T73625	αvβ1 integrin-IN-1 TFA
	αvβ1 Integrin-IN-1 TFA (Compound C8) is a potent, selective inhibitor of αvβ1 integrin, demonstrating an IC 50 value of 0.63 nM. It exhibits antifibrotic effects [1].
T6812L	Cyclo(-RGDfK) TFA		Integrin
	Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).		Integrin
TP1330	Cyclo(RADfK)		Integrin
	Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.Cyclo(RADfK) is a negative control for the cyclo (-RGDfK-), the RGD peptide. RGD...		Integrin
T6812	Cyclo(-RGDfK)	Cyclo (-RGDfK)	Integrin
	Cyclo(-RGDfK) (Cyclo (-RGDfK)) is an effective and specific αvβ3 integrin inhibitor.		Integrin
T7261	Grp94 Inhibitor-1		GPR , HSP
	Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).		GPR , HSP
T8523	ILK-IN-3		Integrin
	ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.		Integrin
T13147	ICAM-1-IN-1		Integrin
			Integrin
T6657	SB273005		Integrin
	SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.		Integrin
TP1204	IRGD peptide	c(CRGDKGPDC)	Integrin
	iRGD peptide (c(CRGDKGPDC)) is a 9-amino acid cyclic peptide (sequence: CRGDKGPDC) and a molecular mimicry agent that was originally identified in an in vivo screening of phage display libraries in tumor-bearing mice.		Integrin
T4259	GLPG0187		Integrin
	GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).		Integrin
TQ0250	CWHM-12		Integrin
	CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).		Integrin
T6813	Cyclo(RGDyK) trifluoroacetate	Cyclo(RGDyK)	Integrin
	Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.		Integrin
T21868	BIO-1211		Integrin
	BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).		Integrin
T21781	A-286982		Integrin
	A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1.		Integrin
TP1474	LXW7		Integrin
	LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. LXW7 is a disulfide cyclic octa-pepti...		Integrin
T2254	A-205804		Integrin
	A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.		Integrin
T12783	RWJ 50271		Integrin
	RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells).		Integrin
T5488	ILK-IN-2	OSU-T315	Integrin
	ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.		Integrin
T3638	Leukadherin-1		Integrin , Complement System
	Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendothelial migration; reduces inflammation.		Integrin , Complement System
T30751	Carotegrast methyl	AJM300	Integrin
	Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.		Integrin
T4400	DIM-C-pPhOH	CDIM8	Apoptosis , Others
	DIM-C-pPhOH (CDIM8) is a nur77 (NR4A1) antagonist,inhibits TGF-β induced cell migration of breast cancer cell lines,promotes ROS/endoplasmic reticulum stress and proapoptotic pathways in pancreatic cancer cell lines,mimi...		Apoptosis , Others
T2494	Cilengitide	EMD 121974	Integrin , Autophagy
	Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.		Integrin , Autophagy
T5310	TR-14035	MDK-1191	Integrin
	TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).		Integrin
T4435	E7820	ER68203-00	Integrin
	E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).		Integrin
T10397	ATN-161 trifluoroacetate salt	ATN-161 TFA salt	Integrin
	ATN-161 trifluoroacetate salt (ATN-161 TFA salt) is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of liver metastases and improves survival in a murine model.		Integrin
T6966	RGD	RGD (Arg-Gly-Asp) Peptides,Arg-Gly-Asp,RGD Peptides	Integrin
	RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.		Integrin
T6182	Tirofiban	L700462,Aggrastat,MK383	Integrin
	Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.		Integrin
T5485	OSU-T315	OSU-T315 (1,5-regioisomer),ILK-IN-2	Apoptosis , Integrin , Autophagy
	OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.		Apoptosis , Integrin , Autophagy
T3977	Lifitegrast	SHP-606,SAR 1118	Integrin
	Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.		Integrin
T7570	RGD peptide (GRGDNP)	RGD peptide GRGDNP(2TFA),RGD peptide GRGDNP	Apoptosis , Integrin
	RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.		Apoptosis , Integrin
T6806	Cilengitide TFA		Integrin , Autophagy
	Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.		Integrin , Autophagy
T2537	Tirofiban hydrochloride monohydrate	Tirofiban Hydrochloride,MK-383 Hydrochloride	ATPase , Integrin
	Tirofiban hydrochloride monohydrate (MK-383 Hydrochloride) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist.		ATPase , Integrin
T1950	PND-1186	PND1186,PND 1186,VS-4718,SR-2516	Apoptosis , FAK
	PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).		Apoptosis , FAK

Compounds

α2β1 Integrin Ligand Peptide acetate

TP1484L

Synonym: α2β1 Integrin Ligand Peptide acetate (134580-64-6)

Integrin modulator 1

T36291

Synonym:

Target:

Integrin Binding Peptide

Integrin Antagonists 27

α2β1 Integrin Ligand Peptide

TP1484

Synonym:

Target:

αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)

T13473L

Synonym: αvβ1 integrin-IN-1 TFA

Target: Integrin

α2β1 Integrin Ligand Peptide TFA

TP1374

Synonym:

Target:

αvβ6 integrin inhibitor 2

T79140

Synonym:

Target: Integrin

Integrin signaling inhibitor, mP13

α7β1 integrin modulator-1

T79918

Synonym:

Target: Integrin

α5β1 integrin agonist-1

αvβ1 integrin-IN-1 TFA

Synonym: Cyclo (-RGDfK)

Synonym: c(CRGDKGPDC)

Cyclo(RGDyK) trifluoroacetate

T6813

Synonym: Cyclo(RGDyK)

Target: Integrin, Complement System

Target: Apoptosis, Others

Cilengitide

T2494

Synonym: EMD 121974

Target: Integrin, Autophagy

ATN-161 trifluoroacetate salt

T10397

Synonym: ATN-161 TFA salt

Target: Integrin

RGD

T6966

Synonym: RGD (Arg-Gly-Asp) Peptides,Arg-Gly-Asp,RGD Peptides

Target: Integrin

Tirofiban

T6182

Synonym: L700462,Aggrastat,MK383

Target: Integrin

OSU-T315

T5485

Synonym: OSU-T315 (1,5-regioisomer),ILK-IN-2

Target: Apoptosis, Integrin, Autophagy

Lifitegrast

T3977

Synonym: SHP-606,SAR 1118

Target: Integrin

RGD peptide (GRGDNP)

T7570

Synonym: RGD peptide GRGDNP(2TFA),RGD peptide GRGDNP

Target: Apoptosis, Integrin

Cilengitide TFA

T6806

Synonym:

Target: Integrin, Autophagy

Tirofiban hydrochloride monohydrate

T2537

Synonym: Tirofiban Hydrochloride,MK-383 Hydrochloride

Target: ATPase, Integrin

PND-1186

T1950

Synonym: PND1186,PND 1186,VS-4718,SR-2516

Target: Apoptosis, FAK

カタログ番号	製品名	別名	ターゲット
T3862	Irigenin		NF-κB , Integrin
	Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enha...		NF-κB , Integrin
T3404	Cucurbitacin B	Cuc B,DATISCACIN,Amarine	Apoptosis , PTEN , Integrin , Endogenous Metabolite , HIF , STAT , Autophagy
	Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inh...
T36715	Tetrac	Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid	Apoptosis , EGFR
	Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blocking EGFR-mediated cell signaling in colorectal cancer cells.Tetrac...		Apoptosis , EGFR
T3834	8-Epideoxyloganic acid		ROS , Immunology/Inflammation related
	8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibl...		ROS , Immunology/Inflammation related
T5S0055	Chelidonine	Helidonine,Khelidonin,Stylophorin	Apoptosis , Others , Influenza Virus
	1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model ...		Apoptosis , Others , Influenza Virus
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
TN5447	Apigenin 7-O-methylglucuronide	Apigenin-7-O-β-D-glucuronide methyl ester
	Apigenin 7-O-methylglucuronide did not affect GAG level or secretion, may potentially be used in osteogenesis imperfecta (OI) type I pharmacotherapy in patients with normal GAG content. Apigenin 7-O-methylglucuronide whi...
T40960	Fibronectin		Integrin
	Fibronectin is a macromolecular glycoprotein found in blood, connective tissue, and cell surfaces that serves as a biomarker for tissue damage.Fibronectin is recognized by the integrin family of surface receptors.Fibrone...		Integrin
T36295	Echistatin TFA
	Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorpti...

天然物製品

Irigenin

T3862

Synonym:

Target: NF-κB, Integrin

Cucurbitacin B

T3404

Synonym: Cuc B,DATISCACIN,Amarine

Target: Apoptosis, PTEN, Integrin, Endogenous Metabolite, HIF, STAT, Autophagy

Tetrac

T36715

Synonym: Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid

Target: Apoptosis, EGFR

8-Epideoxyloganic acid

T3834

Synonym:

Target: ROS, Immunology/Inflammation related

Chelidonine

T5S0055

Synonym: Helidonine,Khelidonin,Stylophorin

Target: Apoptosis, Others, Influenza Virus

Glaucocalyxin A

T4S0498

Synonym: Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

Apigenin 7-O-methylglucuronide

TN5447

Synonym: Apigenin-7-O-β-D-glucuronide methyl ester

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04643	Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His)	Mouse	HEK293 Cells
	Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is NP_032428.2&NP_067334...
TMPY-05716	Integrin alpha V beta 3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor.
TMPY-05717	Integrin alpha V beta 8 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cyto...
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02159	Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 192 kDa and the accession number is P08648&P05556-1.
TMPY-02160	Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 196 kDa and the accession number is P53708&P05556-1.
TMPY-04881	Integrin alpha 6 beta 4 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	Integrin alpha 6 beta 4 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 196 kDa and the accession number is CAA37656.1.
TMPY-05762	Integrin alpha X beta 2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Integrin alpha X beta 2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 204.8 kDa and the accession number is P20702&P05107.
TMPY-02158	Integrin alpha 6 beta 1 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	Integrin alpha 6 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 198 kDa and the accession number is P23229-3&P05556-1.
TMPY-00476	ITGB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involv...
TMPY-02161	Integrin alpha X beta 2 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	Integrin alpha X beta 2 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 205 kDa and the accession number is P20702&P05107.
TMPJ-00211	CD47 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-45 KDa and the accession number is Q08722.
TMPK-00839	ITGB6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide ...
TMPK-01247	ITGB6 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide ...
TMPJ-00810	ITGA5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In cas...
TMPY-02289	CIB2 Protein, Human, Recombinant (His)	Human	E. coli
	Calcium and integrin-binding protein 2 (CIB2) belongs to a protein family with four known members, CIB1 through CIB4, which are characterized by multiple calcium-binding EF-hand domains. Sensorineural hearing loss is gen...
TMPJ-00786	ITGB1 Protein, Human, Recombinant (aa 21-728, His)	Human	HEK293 Cells
	Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue ...
TMPY-02198	ILKAP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Integrin-linked kinase-associated serine/threonine phosphatase 2C, also known as ILKAP, is a cytoplasm protein that belongs to the PP2C family. ILKAP contains one PP2C-like domain. ILKAP is widely expressed. Highest leve...
TMPJ-00614	CD47 Protein, Rhesus macaque, Recombinant (His & Flag)	Rhesus	HEK293 Cells
	CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellular domain (ECD)...
TMPJ-00613	CD47 Protein, Rhesus macaque, Recombinant (hFc)	Rhesus	HEK293 Cells
	CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accession number is F7A802.
TMPJ-00212	CD47 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 48-65 KDa and the accession number is Q08722.
TMPJ-00445	IBSP Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Bone sialoprotein 2(IBSP) is a monomeric non‑collagenous member of the SIBLING family of extracellular matrix proteins. It is principally associated with the early stages of bone mineralization. Mouse IBSP is synthesize...
TMPJ-00209	CD47 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 30-40 KDa and the accession number is Q08722.
TMPJ-00208	CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 60-70 KDa and the accession number is Q08722.
TMPJ-00242	PARVA Protein, Human, Recombinant (His)	Human	E. coli
	Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with i...
TMPH-00213	Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)	Bothrops atrox	E. coli
	Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor a...
TMPH-02569	WISP2/CCN5 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
TMPH-01539	ILK Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered ...
TMPH-03297	LGALS3BP Protein, Rat, Recombinant (His)	Rat	E. coli
	Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
TMPY-02761	Rack1 Protein, Human, Recombinant (His & MBP)	Human	E. coli
	The scaffolding protein, Rack1, is a seven-WD-domain-containing protein that has been implicated in binding to integrin beta subunit cytoplasmic domains and to members of two kinase families (src and protein kinase C, PK...
TMPJ-00352	CD98 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin...
TMPH-03206	ITGB8 Protein, Rabbit, Recombinant (His & Myc)	Rabbit	E. coli
	Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor b...
TMPH-03203	FGFb Protein, Rabbit, Recombinant (His & SUMO)	Rabbit	E. coli
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell di...
TMPH-02570	WISP2/CCN5 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
TMPH-01362	LGALS3BP Protein, Human, Recombinant (His)	Human	E. coli
	Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. LGALS3BP Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted m...
TMPY-05291	CD57/B3gat1 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. Saturating concentrations of rVAR2 inhibited down...
TMPH-01581	KRT1 Protein, Human, Recombinant (His)	Human	E. coli
	May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/H...
TMPK-00635	CDCP1 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPH-02731	ICAM4 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Adhesion molecule that binds to leukocyte adhesion LFA-1 protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins. Isoform 2 may modulate binding of membrane-associated ICA...
TMPK-01010	CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPK-01183	CDCP1 Protein, Human, Recombinant (aa 30-368, His)	Human	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPK-01256	CDCP1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPH-03398	VCAM-1 Protein, Rat, Recombinant (His)	Rat	E. coli
	Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The ...
TMPK-01182	CDCP1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPK-01255	CDCP1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated	Cynomolgus	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPK-01181	CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPH-00368	FGF-2 Protein, Chicken, Recombinant (His)	Chicken	P. pastoris (Yeast)
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation an...
TMPJ-00678	STX6 Protein, Human, Recombinant	Human	E. coli
	Syntaxin-6 (STX6) is a single-pass type IV membrane protein, which belongs to the Syntaxin family. STX6 is mainly localized in the plasma membrane. STX6 contains one t-SNARE coiled-coil homology domain and involved in in...
TMPH-01536	ITGB4 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG...
TMPK-00837	Galectin-3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Human Galectin-3, also known as Mac-2, L29, CBP35, and epsilon BP, is classified as a chimeric member of the Galectin superfamily and contains one carbohydrate recognition domain (CRD) linked to a nonlectin domain.Galact...
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