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Search Results for " BMP "

ターゲット

TGF-beta/Smad

40

阻害剤

9

天然化合物

85

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T7799 BMP signaling agonist sb4 SB 4 TGF-beta/Smad
BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)
T36138 BMP-22
BMP-22 is an inhibitor of autotaxin (IC50 = 170 nM). It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7 at 10 μM. BMP-22 (0.1-1,000 nM) inhibits autotaxin-mediated production of lysophosphatidic acid...
T23840 BUR1 BMP upregulator-1,BMP upregulator 1,BUR 1,BUR-1 CDK
BUR1 is a selective BMP upregulator that acts by increasing the expression of Inhibitor of DNA binding 1 and inducing BMP2 and PTGS2 expression.
T1900 LDN-212854 LDN212854,BMP Inhibitor III ALK , TGF-beta/Smad
LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors; possesses differences towards ALK2(IC50=1.3 nM) versus ALK1/3 compared to other inhibitors.
T79546 BMP agonist 1
BMP Agonist 1 (compound 2 b) is a small-molecule stimulator of bone morphogenic protein (BMP) signaling, crucial for the differentiation of C2C12 cells. It acts by inhibiting GSK3β and enhancing β-catenin signaling, ther...
T10494 Beclomethasone 17-propionate Beclomethasone-17-monopropionate,17-BMP Others
Beclomethasone 17-propionate is an active metabolite of Beclomethasone dipropionate and an agonist of the glucocorticoid receptor (GR). It exhibits greater affinity for GR than Beclomethasone dipropionate. Beclomethasone...
T1977 Dorsomorphin Compound C,BML-275 AMPK , Autophagy , TGF-beta/Smad
Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor ...
T6146 Dorsomorphin dihydrochloride BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride AMPK , Autophagy , TGF-beta/Smad
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.
T82851 BMP2-derived peptide
BMP2-derived peptide, encompassing amino acids 73 to 92 of BMP-2, induces osteogenic differentiation in bone marrow stromal cells (BMSCs) and augments bone regeneration [1].
T30486 BMPSP
BMPSP is a fluorescent DNA groove binding probe.
T14668 BMPS Others
BMPS, a non-cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).
T80174 BmP02 Potassium Channel
BmP02, a compound isolated from Chinese scorpion (Buthus martensi Karsch) venom, acts as a selective Kv1.3 channel blocker and a highly-selective Kv4.2 modulator. It delays Kv4.2 inactivation in HEK293T cells, exhibiting...
T23776 BBMP
BBMP is an inhibitor of mitochondrial permeability transition pore.
T79223 BMPR2-IN-1
BMPR2-IN-1 (Compound 8a), is a potent inhibitor of BMPR2, exhibiting an IC50 value of 506 nM and a Kd of 83.5 nM. It is utilized in the study of various diseases including pulmonary arterial hypertension, Alzheimer's dis...
T60644 SJ000063181 TGF-beta/Smad
SJ000063181 is a potent activator of BMP signaling, exhibiting an EC50 of ≤1 μM. It serves as a valuable chemical probe for BMP signaling analysis, owing to its ability to penetrate zebrafish embryos.
T4662 SJ000291942 TGF-beta/Smad
SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.
T35348 LDN-193189 2HCl LDN-193189 2HCl,DM-3189 2HCl ALK , TGF-beta/Smad
LDN-193189 2HCl (DM-3189 2HCl) is a selective BMP signaling inhibitor that inhibits ALK1,ALK2,ALK3 and ALK6, showing IC50s of 0.8 nM, 0.8 nM, 5.3 nM, and 16.7 nM, respectively, in kinase assays.LDN-193189 2HCl inhibited ...
T1942 DMH-1 DMH1 ALK , Autophagy , TGF-beta/Smad
DMH-1 is a potent and selective BMP inhibitor.
T61301 Chromenone 1 TGF-beta/Smad
Chromenone 1 is a potent potentiator of osteogenic bone morphogenetic protein (BMP). Chromenone 1 induces a pronounced, kinase-independent, negative TGFβ feedback that enhances nuclear BMP-Smad signaling outputs.
T6158 LDN-193189 HCl LDN193189 Hydrochloride ALK
LDN-193189 HCl (LDN193189 Hydrochloride) is a selective BMP type I receptor kinases inhibitor.
T15780 LP-922761 AAK1 (AP2 associated kinase 1)
LP-922761 is a potent, selective, and orally active AAK1 inhibitor with inhibitory effects on BMP-2 induced protein kinase (BIKE).
T35896 AZ 12799734 AZ12799734 ALK
AZ 12799734 is an orally active, selective and potent dual inhibitor of TGFBR1 and ALK5 with inhibitory effects on BMP and TGFβ for the study of tumours.
T16904 Smurf1-IN-A01 A01 Others
Smurf1-IN-A01 (A01) is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM). It increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.
T10572 BMT-124110 AAK1 (AP2 associated kinase 1)
BMT-124110 is a selective AAK1 inhibitor (IC50: 0.9 nM) with antinociceptive activity. BMT-090605 inhibited BMP-2 induced protein kinase BIKE with IC50 of 17 nM. BMT-090605 inhibits cyclin G-associated kinase GAK with an...
T1935 LDN193189 LDN-193189,DM-3189,LDN 193189 ALK , TGF-beta/Smad
LDN193189 (LDN-193189) (DM 3189) is a selective BMP signaling inhibitor, inhibiting the transcriptional activity of ALK2 and ALK3 (IC50s: 0.8/0.8/5.3/16.7 nM for ALK1/2/3/6).
T10572L BMT-124110 Formate BMT-124110 Formate（1679371-59-5 Free base） Serine/threonin kinase , TGF-beta/Smad , AAK1 (AP2 associated kinase 1)
BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the ce...
T76863 Elezanumab AE12-1Y-QL,ABT-555 TGF-beta/Smad
Elezanumab(ABT-555) is a potent human anti-RGMa monoclonal antibody.Elezanumab exerts its inhibitory effect on RGMa-mediated BMP signaling through the SMAD1/5/8 pathway, with an IC50 of approximately 97 pM.Elezanumab pro...
T1914 K02288 K 02288 ALK , TGF-beta/Smad
K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.
T1800 GW788388 GW 788388 ALK , TGF-beta/Smad
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.
T6064 UK-383367 UK 383367 Procollagen C Proteinase
UK-383367 is a procollagen C-proteinase inhibitor with IC50 of 44 nM, has excellent selectivity over MMPs.
T25346 DMH2 DMH-2,DMH 2
DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.
T60429 SY-LB-57
SY-LB-57 is a highly effective agonist of bone morphogenetic protein (BMP) receptor signaling. SY-LB-57 can be used in studies of conditions such as bone fracture and pulmonary arterial hypertension [1].
T78102 ER 50891 quarterhydrate
ER 50891 quarterhydrate is a potent RARα (retinoic acid receptor α) antagonist that markedly diminishes the inhibitory effects of ATRA (all-trans retinoic acid) on osteoblastogenesis induced by BMP 2 (bone morphogenetic ...
T14691 BMT-090605 Others
BMT-090605 is a potent, selective AAK1 inhibitor, with an IC50 of 0.6 nM. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 45 and 60 nM, respectively[1]. BMT-09...
T16446 PD 407824 PD-407824 Wee1 , Chk
PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respective...
T62143 LP-922761 hydrate
LP-922761 hydrate is a selective, potent, orally active AAK1 inhibitor with IC50 values of 4.8 nM and 7.6 nM in enzyme and cellular assays, respectively. LP-922761 hydrate inhibits BMP-2 inducible protein kinase (BIKE) (...
T61941 BMT-090605 hydrochloride
BMT-090605 hydrochloride is an effective and selective inhibitor of connexin-2 associated kinase 1 (AAK1) (IC50=0.6 nM). BMT-090605 hydrochloride inhibits BMP-2 induced protein kinase (BIKE) (IC50=45 nM) and cyclin G-rel...
T60365 SY-LB-35
SY-LB-35, a potent bone morphogenetic protein (BMP) receptor agonist, significantly enhances cell number and viability in the C2C12 myoblast cell line. It promotes cell cycle progression, particularly towards the S and G...
T35541 Lipoxygenin
Lipoxygenin is an inhibitor of 5-lipoxygenase (5-LO) with an IC50value of 5 μM for inhibition of 5-LO product synthesis in isolated human granulocytes stimulated with the cation ionophore A23187 .1It inhibits hedgehog-de...
T37441 KMN-80
The prostaglandin E receptor 4 (EP4) is one of four G protein-coupled receptors that mediate the actions of prostaglandin E2 . Binding of PGE2 to the EP4 receptor causes an increase in intracellular cyclic AMP, which pla...

Compounds

BMP signaling agonist sb4
T7799
Synonym: SB 4
Target: TGF-beta/Smad
BMP-22
T36138
Synonym:
Target:
BUR1
T23840
Synonym: BMP upregulator-1,BMP upregulator 1,BUR 1,BUR-1
Target: CDK
LDN-212854
T1900
Synonym: LDN212854,BMP Inhibitor III
Target: ALK, TGF-beta/Smad
BMP agonist 1
T79546
Synonym:
Target:
Beclomethasone 17-propionate
T10494
Synonym: Beclomethasone-17-monopropionate,17-BMP
Target: Others
Dorsomorphin
T1977
Synonym: Compound C,BML-275
Target: AMPK, Autophagy, TGF-beta/Smad
Dorsomorphin dihydrochloride
T6146
Synonym: BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride
Target: AMPK, Autophagy, TGF-beta/Smad
BMP2-derived peptide
T82851
Synonym:
Target:
BMPSP
T30486
Synonym:
Target:
BMPS
T14668
Synonym:
Target: Others
BmP02
T80174
Synonym:
Target: Potassium Channel
BBMP
T23776
Synonym:
Target:
BMPR2-IN-1
T79223
Synonym:
Target:
SJ000063181
T60644
Synonym:
Target: TGF-beta/Smad
SJ000291942
T4662
Synonym:
Target: TGF-beta/Smad
LDN-193189 2HCl
T35348
Synonym: LDN-193189 2HCl,DM-3189 2HCl
Target: ALK, TGF-beta/Smad
DMH-1
T1942
Synonym: DMH1
Target: ALK, Autophagy, TGF-beta/Smad
Chromenone 1
T61301
Synonym:
Target: TGF-beta/Smad
LDN-193189 HCl
T6158
Synonym: LDN193189 Hydrochloride
Target: ALK
LP-922761
T15780
Synonym:
Target: AAK1 (AP2 associated kinase 1)
AZ 12799734
T35896
Synonym: AZ12799734
Target: ALK
Smurf1-IN-A01
T16904
Synonym: A01
Target: Others
BMT-124110
T10572
Synonym:
Target: AAK1 (AP2 associated kinase 1)
LDN193189
T1935
Synonym: LDN-193189,DM-3189,LDN 193189
Target: ALK, TGF-beta/Smad
BMT-124110 Formate
T10572L
Synonym: BMT-124110 Formate（1679371-59-5 Free base）
Target: Serine/threonin kinase, TGF-beta/Smad, AAK1 (AP2 associated kinase 1)
Elezanumab
T76863
Synonym: AE12-1Y-QL,ABT-555
Target: TGF-beta/Smad
K02288
T1914
Synonym: K 02288
Target: ALK, TGF-beta/Smad
GW788388
T1800
Synonym: GW 788388
Target: ALK, TGF-beta/Smad
UK-383367
T6064
Synonym: UK 383367
Target: Procollagen C Proteinase
DMH2
T25346
Synonym: DMH-2,DMH 2
Target:
SY-LB-57
T60429
Synonym:
Target:
ER 50891 quarterhydrate
T78102
Synonym:
Target:
BMT-090605
T14691
Synonym:
Target: Others
PD 407824
T16446
Synonym: PD-407824
Target: Wee1, Chk
LP-922761 hydrate
T62143
Synonym:
Target:
BMT-090605 hydrochloride
T61941
Synonym:
Target:
SY-LB-35
T60365
Synonym:
Target:
Lipoxygenin
T35541
Synonym:
Target:
KMN-80
T37441
Synonym:
Target:
カタログ番号 製品名 別名 ターゲット
TN2081 Maohuoside A MAPK
Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.
T0683 Mevastatin Compactin,ML236B Apoptosis , Antibacterial , Antibiotic , HMG-CoA Reductase , Autophagy , Lipid
Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
T19719 TBMP butylated hydroxyanisole Others
TBMP (butylated hydroxyanisole) is the viral envelope protein hemagglutinin (HA)-mediated entry novel inhibitor.
T5729 L-quebrachitol Wnt/beta-catenin
L-quebrachitol is a natural product.L-quebrachitol may promote osteoblastogenesis by triggering the BMP-2-response as well as the Runx2, MAPK, and Wnt/β-catenin signaling pathway.
T2845 Imperatorin Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen TRP/TRPV Channel , AChR , AChE , NOD
Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
T4S1943 Kirenol Kirel Wnt/beta-catenin
1. Kirenol (Kirel) has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid...
T3005 4-Hydroxychalcone P-Cinnamoylphenol Others , NF-κB
4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.
T2698 Asperosaponin VI Akebia saponin D,Asperosaponin Ⅵ Apoptosis , Others , Caspase
Asperosaponin VI (Akebia saponin D) , the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.
T3673 Mollugin Rubimaillin HER , JAK
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr...

天然物製品

Maohuoside A
TN2081
Synonym:
Target: MAPK
Mevastatin
T0683
Synonym: Compactin,ML236B
Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid
TBMP
T19719
Synonym: butylated hydroxyanisole
Target: Others
L-quebrachitol
T5729
Synonym:
Target: Wnt/beta-catenin
Imperatorin
T2845
Synonym: Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen
Target: TRP/TRPV Channel, AChR, AChE, NOD
Kirenol
T4S1943
Synonym: Kirel
Target: Wnt/beta-catenin
4-Hydroxychalcone
T3005
Synonym: P-Cinnamoylphenol
Target: Others, NF-κB
Asperosaponin VI
T2698
Synonym: Akebia saponin D,Asperosaponin Ⅵ
Target: Apoptosis, Others, Caspase
Mollugin
T3673
Synonym: Rubimaillin
Target: HER, JAK

Recombinant Proteins

Species：
Human (47)
Mouse (25)
Canine (3)
Cynomolgus (3)
Human,Mouse,Rat,Rhesus,Canine (2)
Bovine (1)
Danio rerio (zebrafish) (1)
Human,Mouse,Rat (1)
Human,Mouse,Rat (1)
Rat (1)
Expression System：
HEK293 (45)
E. coli (17)
Human Cells (13)
Baculovirus-Insect Cells (9)
Baculovirus (1)
Tag：
His (20)
hFc (17)
C-6His (7)
N-terminal 6xHis-tagged (6)
Tag Free (6)
His,GST (4)
His,hFc (4)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (3)
None (3)
C-Fc (2)
カタログ番号 製品名 Species Expression System
TMPH-01015 BMP-3 Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of ce...
TMPH-01017 BMP-4 Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu...
TMPH-01014 BMP-2 Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis. Induces cartilage and bone formation. Initiates the canonical...
TMPY-06842 BMP-4 Protein, Human, Recombinant (E399D) Human E. coli
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPH-00228 BMP-4 Protein, Bovine, Recombinant (GST) Bovine E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu...
TMPY-00484 Cerberus 1/CER1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Cerberus 1/CER1 Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 29.6 kDa. Accession number: AAH69371.1
TMPH-01018 BMP-6 Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes including cartilage and bone formation. Plays also an important role in the regulation of iron metabolism by acting as ...
TMPH-01013 BMP-15 Protein, Human, Recombinant (His & Myc) Human E. coli
May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.
TMPY-00431 BMP-4 Protein, Mouse, Recombinant (rFc) Mouse HEK293
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPH-01019 BMP-7 Protein, Human, Recombinant (GST) Human E. coli
Growth factor of the TGF-beta superfamily that plays important role in various biological processes, including embryogenesis, hematopoiesis, neurogenesis and skeletal morphogenesis. Initiates the canonical BMP signaling ...
TMPH-01012 BMP-1 Protein, Human, Recombinant (His) Human E. coli
Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins. Thereby participates ...
TMPY-00680 BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) Human,Mouse,Rat,Rhesus,Canine HEK293
BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPJ-01473 BMP-7 Protein, Human, Recombinant Human Human Cells
Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist,...
TMPY-03127 BAMBI Protein, Mouse, Recombinant (hFc) Mouse HEK293
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellu...
TMPY-04334 BAMBI Protein, Mouse, Recombinant (His) Mouse HEK293
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellu...
TMPY-01456 BAMBI Protein, Human, Recombinant (His) Human HEK293
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellu...
TMPY-00681 BMP-5 Protein, Human, Recombinant (hFc) Human HEK293
Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily....
TMPH-02552 BMP3 Protein, Mouse, Recombinant (Myc) Mouse E. coli
Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.
TMPY-03297 BMP-2 Protein, Danio rerio (zebrafish), Recombinant Danio rerio (zebrafish) E. coli
BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-02670 NBL1 Protein, Mouse, Recombinant (His) Mouse HEK293
The Dan (Differential screening-selected gene aberrative in neuroblastoma, also known as N03) gene was first identified as the putative rat tumor suppressor gene and encodes a protein structurally related to Cerberus and...
TMPY-01039 NBL1 Protein, Human, Recombinant (His) Human HEK293
The Dan (Differential screening-selected gene aberrative in neuroblastoma, also known as N03) gene was first identified as the putative rat tumor suppressor gene and encodes a protein structurally related to Cerberus and...
TMPJ-00713 GDF-11 Protein, Human, Recombinant Human Human Cells
Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. ...
TMPY-01136 BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant Human,Mouse,Rat,Rhesus,Canine E. coli
BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-00771 NBL1 Protein, Human, Recombinant (hFc) Human HEK293
The Dan (Differential screening-selected gene aberrative in neuroblastoma, also known as N03) gene was first identified as the putative rat tumor suppressor gene and encodes a protein structurally related to Cerberus and...
TMPH-01079 CLN5 Protein, Human, Recombinant (His) Human E. coli
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal memb...
TMPJ-00966 GDF-5 Protein, Human, Recombinant Human E. coli
Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor...
TMPJ-00325 BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His) Human Human Cells
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A i...
TMPY-01059 BMPR2 Protein, Human, Recombinant (His) Human HEK293
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPY-00683 BMPR2 Protein, Human, Recombinant (His & hFc) Human HEK293
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPY-00962 BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-01374 BMPR1A/ALK-3 Protein, Mouse, Recombinant (His) Mouse HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-00614 BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc) Canine HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-05485 BMPR1A/ALK-3 Protein, Human, Recombinant (hFc) Human HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-01764 BMPR1A/ALK-3 Protein, Human, Recombinant (His) Human HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-04496 BMPRIB Protein, Mouse, Recombinant (hFc) Mouse HEK293
BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These pro...
TMPY-03362 BMPRIB Protein, Human, Recombinant (hFc) Human HEK293
BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These pro...
TMPY-04367 BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST) Human Baculovirus-Insect Cells
BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These pro...
TMPJ-00476 BMPG Protein, Human, Recombinant (His) Human Human Cells
Bone Marrow Proteoglycan (BMPG) is a secreted protein that contains one C-type lectin domain. BMPG is the predominant constituent of the crystalline core of the eosinophil granule. BMPG is highly expressed in placenta an...
TMPY-02594 Noggin/NOG Protein, Mouse, Recombinant (hFc) Mouse HEK293
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPY-00890 Noggin/NOG Protein, Human, Recombinant (hFc) Human HEK293
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPY-05202 Noggin/NOG Protein, Human, Recombinant Human HEK293
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPJ-01065 Noggin/NOG Protein, Mouse, Recombinant (His) Mouse Human Cells
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept...
TMPY-04774 ALK-2/ACVR1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03014 Osteoactivin/GPNMB Protein, Mouse, Recombinant (His) Mouse HEK293
GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteocla...
TMPJ-01322 TWSG1 Protein, Human, Recombinant (His) Human Human Cells
Twisted Gastrulation Protein Homolog 1 (TWSG1) is a 22 kDa secreted protein that belongs to the twisted gastrulation protein family. Human TWSG1 is synthesized as a 223 aa precursor that contains a 25 aa signal peptide a...
TMPK-01152 CHRDL1 Protein, Human, Recombinant (His) Human E. coli
CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular s...
TMPY-01433 Noggin/NOG Protein, Human, Recombinant (His) Human HEK293
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPH-02213 Tomoregulin-1 Protein, Human, Recombinant (E. coli, His) Human E. coli
May inhibit NODAL and BMP signaling during neural patterning. May be a tumor suppressor in brain cancers.
TMPY-01817 GDF-10 Protein, Mouse, Recombinant (hFc) Mouse HEK293
BMP-3b / GDF-10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a ma...
TMPJ-01294 SOST Protein, Mouse, Recombinant (His) Mouse Human Cells
Sclerostin (SOST) is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. Cerberus/DAN family members are putative BMP antagonists, and include Dan, Cerberus, Gre...
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BMP-3 Protein, Human, Recombinant (His)
TMPH-01015
Species: Human
Expression System: E. coli
BMP-4 Protein, Human, Recombinant (His)
TMPH-01017
Species: Human
Expression System: E. coli
BMP-2 Protein, Human, Recombinant (His)
TMPH-01014
Species: Human
Expression System: E. coli
BMP-4 Protein, Human, Recombinant (E399D)
TMPY-06842
Species: Human
Expression System: E. coli
BMP-4 Protein, Bovine, Recombinant (GST)
TMPH-00228
Species: Bovine
Expression System: E. coli
Cerberus 1/CER1 Protein, Human, Recombinant (His)
TMPY-00484
Species: Human
Expression System: Baculovirus-Insect Cells
BMP-6 Protein, Human, Recombinant (His)
TMPH-01018
Species: Human
Expression System: E. coli
BMP-15 Protein, Human, Recombinant (His & Myc)
TMPH-01013
Species: Human
Expression System: E. coli
BMP-4 Protein, Mouse, Recombinant (rFc)
TMPY-00431
Species: Mouse
Expression System: HEK293
BMP-7 Protein, Human, Recombinant (GST)
TMPH-01019
Species: Human
Expression System: E. coli
BMP-1 Protein, Human, Recombinant (His)
TMPH-01012
Species: Human
Expression System: E. coli
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)
TMPY-00680
Species: Human,Mouse,Rat,Rhesus,Canine
Expression System: HEK293
BMP-7 Protein, Human, Recombinant
TMPJ-01473
Species: Human
Expression System: Human Cells
BAMBI Protein, Mouse, Recombinant (hFc)
TMPY-03127
Species: Mouse
Expression System: HEK293
BAMBI Protein, Mouse, Recombinant (His)
TMPY-04334
Species: Mouse
Expression System: HEK293
BAMBI Protein, Human, Recombinant (His)
TMPY-01456
Species: Human
Expression System: HEK293
BMP-5 Protein, Human, Recombinant (hFc)
TMPY-00681
Species: Human
Expression System: HEK293
BMP3 Protein, Mouse, Recombinant (Myc)
TMPH-02552
Species: Mouse
Expression System: E. coli
BMP-2 Protein, Danio rerio (zebrafish), Recombinant
TMPY-03297
Species: Danio rerio (zebrafish)
Expression System: E. coli
NBL1 Protein, Mouse, Recombinant (His)
TMPY-02670
Species: Mouse
Expression System: HEK293
NBL1 Protein, Human, Recombinant (His)
TMPY-01039
Species: Human
Expression System: HEK293
GDF-11 Protein, Human, Recombinant
TMPJ-00713
Species: Human
Expression System: Human Cells
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant
TMPY-01136
Species: Human,Mouse,Rat,Rhesus,Canine
Expression System: E. coli
NBL1 Protein, Human, Recombinant (hFc)
TMPY-00771
Species: Human
Expression System: HEK293
CLN5 Protein, Human, Recombinant (His)
TMPH-01079
Species: Human
Expression System: E. coli
GDF-5 Protein, Human, Recombinant
TMPJ-00966
Species: Human
Expression System: E. coli
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
TMPJ-00325
Species: Human
Expression System: Human Cells
BMPR2 Protein, Human, Recombinant (His)
TMPY-01059
Species: Human
Expression System: HEK293
BMPR2 Protein, Human, Recombinant (His & hFc)
TMPY-00683
Species: Human
Expression System: HEK293
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc)
TMPY-00962
Species: Mouse
Expression System: HEK293
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His)
TMPY-01374
Species: Mouse
Expression System: HEK293
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
TMPY-00614
Species: Canine
Expression System: HEK293
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc)
TMPY-05485
Species: Human
Expression System: HEK293
BMPR1A/ALK-3 Protein, Human, Recombinant (His)
TMPY-01764
Species: Human
Expression System: HEK293
BMPRIB Protein, Mouse, Recombinant (hFc)
TMPY-04496
Species: Mouse
Expression System: HEK293
BMPRIB Protein, Human, Recombinant (hFc)
TMPY-03362
Species: Human
Expression System: HEK293
BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST)
TMPY-04367
Species: Human
Expression System: Baculovirus-Insect Cells
BMPG Protein, Human, Recombinant (His)
TMPJ-00476
Species: Human
Expression System: Human Cells
Noggin/NOG Protein, Mouse, Recombinant (hFc)
TMPY-02594
Species: Mouse
Expression System: HEK293
Noggin/NOG Protein, Human, Recombinant (hFc)
TMPY-00890
Species: Human
Expression System: HEK293
Noggin/NOG Protein, Human, Recombinant
TMPY-05202
Species: Human
Expression System: HEK293
Noggin/NOG Protein, Mouse, Recombinant (His)
TMPJ-01065
Species: Mouse
Expression System: Human Cells
ALK-2/ACVR1 Protein, Human, Recombinant (His)
TMPY-04774
Species: Human
Expression System: Baculovirus-Insect Cells
Osteoactivin/GPNMB Protein, Mouse, Recombinant (His)
TMPY-03014
Species: Mouse
Expression System: HEK293
TWSG1 Protein, Human, Recombinant (His)
TMPJ-01322
Species: Human
Expression System: Human Cells
CHRDL1 Protein, Human, Recombinant (His)
TMPK-01152
Species: Human
Expression System: E. coli
Noggin/NOG Protein, Human, Recombinant (His)
TMPY-01433
Species: Human
Expression System: HEK293
Tomoregulin-1 Protein, Human, Recombinant (E. coli, His)
TMPH-02213
Species: Human
Expression System: E. coli
GDF-10 Protein, Mouse, Recombinant (hFc)
TMPY-01817
Species: Mouse
Expression System: HEK293
SOST Protein, Mouse, Recombinant (His)
TMPJ-01294
Species: Mouse
Expression System: Human Cells
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カタログ番号 製品名
L7900 Osteogenesis Compound Library

317 compounds
A unique collection of 317 osteogenesis related compounds for high throughput and high content screening;

ライブラリー

Osteogenesis Compound Library
L7900
Compounds: 317
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