| T5807 |
Stylopine hydrochloride
|
|
NOS
,
COX
|
|
Stylopine is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity. |
| T8187 |
Tetrahydroepiberberine
|
|
Others
,
Influenza Virus
,
Antifungal
|
|
Tetrahydroepiberberine, an isoquinoline alkaloid, has antifungal and selective inhibition against the PI-3 virus activities. |
| T2714 |
L-(R,S)-Tetrahydropalmatine
|
TETRAHYDROPALMATINE HYDROCHLORIDE |
Dopamine Receptor
,
5-HT Receptor
|
|
L-(R,S)-Tetrahydropalmatine (Rotundine) is extracted from Corydalis yanhusuo W. T. Wang. |
| T2793 |
Tetrahydropalmatine
|
DL-Tetrahydropalmatine,Rotundine |
Apoptosis
,
Others
,
Dopamine Receptor
|
|
Tetrahydropalmatine (DL-Tetrahydropalmatine) is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epileptic attack in rats. |
| T2850 |
Bicuculline
|
(+)-Bicuculline,d-Bicuculline |
GABA Receptor
|
|
Bicuculline ((+)-Bicuculline) is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungos... |
| TQ0176 |
(-)-Isocorypalmine
|
Tetrahydrocolumbamine,(S)-Tetrahydrocolumbamine |
Dopamine Receptor
,
Antifungal
|
|
(-)-Isocorypalmine ((S)-Tetrahydrocolumbamine), a natural product isolated from Corydalis chaerophylla, has significant antifungal activity. |
| T2917 |
Tetrahydropalmatine hydrochloride
|
1-Tetrahydropalmitine HCl,Gindarine hydrochloride |
Others
,
Dopamine Receptor
|
|
Tetrahydropalmatine hydrochloride (Gindarine hydrochloride) is an isoquinoline alkaloid found in several different plant species, mainly in the Corydalis genus (Yan Hu Suo). It is a potent muscle relaxant. |
| T2S2362 |
Dehydrocorydaline nitrate
|
|
BCL
,
Others
,
PARP
,
p38 MAPK
,
Caspase
,
Parasite
,
Autophagy
|
|
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially a... |
| T9862 |
Pseudocoptisine chloride
|
Isocoptisine chloride |
AChE
|
|
Pseudocoptisine chloride (Isocoptisine chloride) is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity (IC50 = 12.8 μ... |
| T2874 |
Tetrahydroberberine
|
Tetrahydroberberine THB,Canadine |
Dopamine Receptor
,
5-HT Receptor
|
|
Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors. |
| T3A2467 |
Allocryptopine
|
Thalictrimine,Fagarine I |
Potassium Channel
|
|
Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively. |
| T5S2360 |
Corydaline
|
Corydalin,(+)-Corydaline |
P450
,
Virus Protease
,
Opioid Receptor
,
AChE
|
|
1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr... |
| T5S2357 |
Acetylcorynoline
|
(+)-Corynoline Acetate,O-Acetylcorynoline |
Antifungal
|
|
1. Acetylcorynoline (O-Acetylcorynoline) has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3... |
| T81008 |
Tetrahydropalmatrubine
|
|
|
|
Tetrahydropalmatrubine, an alkaloid, is isolated from the herb Corydalis saxicola [1]. |
| TN1607 |
Epicorynoxidine
|
|
Others
|
|
Epicorynoxidine is an alkaloid derived from the herbs of Corydalis tashiroi. |
| T12570 |
Pseudocoptisine acetate
|
Isocoptisine acetate |
Others
|
|
Pseudocoptisine acetate is a quaternary alkaloid isolated from the tubers of Corydalis turtschaninovii,with anti-inflammatory properties. |
| T82680 |
Corycavine
|
|
|
|
Corycavine, an alkaloid, can be isolated from Corydalis remota [1]. |
| T8189 |
Dihydroberberine
|
|
Potassium Channel
,
HSP
,
HER
|
|
Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interacti... |
| T81159 |
Sibiricine
|
|
|
|
Sibiricine (Compound 8), an isoquinoline alkaloid extracted from the medicinal plant Corydalis crispa, exhibits substantial anti-inflammatory effects by inhibiting TNF-α production in LPS-activated THP-1 cells [1]. |
| T4S2063 |
Tetrahydrocoptisine
|
STYLOPINE |
ERK
,
p38 MAPK
,
NF-κB
|
|
1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may invo... |
| T6S2356 |
Corynoline
|
(+)-Corynoline |
Nrf2
,
AChE
|
|
1. Corynoline ((+)-Corynoline) is an acetylcholinesterase inhibitor. |
| TN1189 |
13-Methylberberine chloride
|
13-Methylberberine |
Others
|
|
13-Methylberberine chloride shows anti-adipogenic effect on 3T3-L1 adipocytes, it has potential as an anti-obesity drug |
| T5S2059 |
Glaucine
|
|
Calcium Channel
,
Dopamine Receptor
,
Influenza Virus
,
Adrenergic Receptor
,
PDE
|
|
Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of h... |
| T5S2361 |
Epiberberine
|
|
ERK
,
Beta-Secretase
,
MEK
,
BACE
,
AMPK
,
AChR
,
AChE
|
|
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/ERK1/2 and AMPKα/Akt pathways during 3T3-L1 adipocyte diffe... |
| T5S2358 |
Dehydrocorydaline
|
Dehydrocorydalin,13-Methylpalmatine |
BCL
,
PARP
,
p38 MAPK
,
Caspase
,
Parasite
,
Autophagy
|
|
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz... |
| TN1139 |
Dehydrocavidine
|
Dehydrocorydaline |
BCL
,
PARP
|
|
Dehydrocavidine (Dehydrocorydaline) has antitumor activity, it inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP. |
| TN3574 |
Canadine
|
|
P450
|
|
Canadine has antioxidant activity with low-toxic effect. |
| TN1561 |
Dehydroglaucine
|
|
Antifection
|
|
Dehydroglaucine is an acetylcholinesterase inhibitor, it shows antimicrobial activity against Staphylococcus aureus, Mycobacterium smegmatis, Candida albicans, and Aspergillus niger. |
| TN1526 |
Corydalmine
|
|
P450
,
Antifection
|
|
Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains.1-Corydalmine significantly inhibits spore germination of all the fungi at 100 to 1500 ppm. l-Coryda... |
| T2S2363 |
Corydine
|
|
IL Receptor
,
Antifection
|
|
Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant and CNS depressant activities. Injected intravenously in ra... |
