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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T38260 | SP 600125, negative control | JNK Inhibitor II, negative control | |
SP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125. SP 600125, negative control inhibits DTP3 and GADD45β/MKK7 (growth arrest and DNA damage-inducible β/me... | |||
T41227 | ARCC 4 negative control | ||
ARCC 4 negative control is a negative control for ARCC 4. Binds androgen receptors (AR) without inducing degradation. | |||
T39317 | ELA-14 negative control | ||
ELA-14 negative control is an inactive peptide that serves as a negative control for ELA-14. | |||
T74869 | SiRNA Negative Control | ||
siRNA Negative Control, a 21-nucleotide siRNA, serves as a negative control. | |||
TP2203 | Bax inhibitor peptide, negative control | Others | |
The compound is a negative control peptide for the Bax inhibitor peptides V5 and P5. | |||
T71316 | ERK Inhibitor II (Negative control) | ||
ERK Inhibitor II (Negative control) effectively blocks extracellular signal-regulated kinase (ERK) and interferes with insulin receptor activation, serving as a useful tool in diabetes research. | |||
T73997 | Anti gram-positive/negative bacteria agent 1 | ||
Anti gram-positive/negative bacteria agent 1 is an antibiotic linked with a synthetic MECAM-based siderophore, serving as a conjugate aimed at combating gram-positive and gram-negative bacteria. | |||
T41214 | (S)-BAY-293 | BAY 294,BAY 293 Negative Control | Ras |
(S)-BAY-293 is a potent pan-KRAS inhibitor for the study of primary non-small lung and pancreatic cancers. | |||
T9407 | Rasarfin | Others , Ras | |
Rasarfin inhibits Ras and ARF6. | |||
T83705 | BING TFA | Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria | |
BING, a antimicrobial peptide discovered in Japanese medaka fish (O. laptipes), originates from vacuolar protein sorting-associated protein 13D-like (Vps13D). It exhibits efficacy against a range of Gram-negative and Gra... | |||
T14391 | Azidamfenicol | Antibacterial , Antibiotic | |
Azidamfenicol inhibits ribosomal peptidyltransferase with a Ki of 22 µM. Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic. | |||
T19858 | Brodimoprim | DHFR , Antibacterial | |
Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR). Brodimoprim is also a long-acting broad-spectrum antibacterial agent characterized by a good pharmacokinetic profile. | |||
T23150 | PHGDH-inactive | Others | |
inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 and NCT-503 | |||
T9680 | Irloxacin | Antibacterial | |
Irloxacin is a new quinolone derivative, and shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. | |||
T19578 | TH-263 | Others | |
TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative. | |||
T22711 | DCB | 3,3'-dichlorobenzaldazine | Others , GluR |
DCB (3,3'-dichlorobenzaldazine) is an allosteric ligand for mGluR5 and shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB). DCB blocks the positive allosteric regulation of mGluRs with the help of ... | |||
T41256 | SP-96 | Aurora Kinase | |
SP-96 is a highly effective and selective inhibitor of Aurora B with an IC50 of 0.316 nM. SP-96 shows selective growth inhibition in NCI60 screening, including MDA-MD-468 (GI50=107 nM). SP-96 can be used in triple negati... | |||
T20525 | Chloramphenicol palmitate | Antibacterial , Antibiotic | |
Chloramphenicol palmitate is a broad-spectrum antibiotic with activity against gram-positive and gram-negative bacteria. Chloramphenicol palmitate can be used in studies about acting as a bacterial selection agent in tra... | |||
T9468 | FR054 | Others | |
FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect. FR054 induces in different breast cancer cells a dramatic decrease in cell proliferation and su... | |||
T9183 | Ralmitaront | RO6889450 | Others |
Ralmitaront (RO6889450) is a potent, orally active partial agonist of the trace amine-associated receptor 1 (TAAR1). | |||
T9699 | TAK-615 | LPA Receptor | |
TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors. | |||
T13780 | MS1943 | Apoptosis , Histone Methyltransferase | |
MS1943 is a orally bioavailable EZH2 selective degrader(IC50 of 120 nM). | |||
T4998L | Cefpodoxime (free acid) | Others | |
Cefpodoxime (free acid) is an oral, third-generation cephalosporin antibiotic. It is active against most Gram-positive and Gram-negative organisms, except Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. | |||
T24677 | PS47 | PS 47,PS-47 | PDK |
PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1. | |||
T22027 | AH-7614 | AH 7614 | GPR |
AH-7614 (AH 7614) is a selective and potent free fatty acid receptor 4 (FFA4/GPR120) antagonist. | |||
T0116 | Balofloxacin | DNA gyrase , Antibacterial , Antibiotic | |
Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase. | |||
T5006 | Flucloxacillin sodium | floxacillin sodium | Antibacterial , Antibiotic |
Flucloxacillin sodium (floxacillin sodium) is a highly active antibiotic against Gram-negative and Gram-positive bacteria. | |||
T23101 | O-3M3FBS | Others | |
Inactive analog of m-3M3FBS (PLC activator) | |||
T0921 | Sulfabenzamide | Sultrin,N-Sulfanilylbenzamide | Antibacterial , Antibiotic , Autophagy |
Sulfabenzamide (N-Sulfanilylbenzamide) is a sulfonamide antibacterial agent used alone or with sulfathiazole and sulfacetamide as a topical, intravaginal antibacterial preparation. | |||
T71314 | GL-V9 | ||
GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy. | |||
T0274 | Cinoxacin | Compound 64716 | Topoisomerase , Antibacterial , Antibiotic |
Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics. Its activity was similar to oxolinic acid and nalidixic acid. | |||
T6582 | Mezlocillin Sodium | Baycipen | Antibacterial , Antibiotic |
Mezlocillin Sodium (Baycipen) is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. | |||
T1008 | Cephalexin | Cefalexin,Cephacillin | Antibacterial , Antibiotic |
Cephalexin (Cephacillin) is a cephalosporin antibiotic. | |||
T3117 | Marbofloxacin | Marbofloxacine,Zeniquin,Marbocyl | Topoisomerase , Antibacterial , Antibiotic |
Marbofloxacin (Zeniquin) is an effective, broad-spectrum antibiotic of bacterial, which inhibits DNA replication. | |||
T11438 | GNE-1858 | Others , MAPK | |
T8954 | ML179 | ML-179 | Others |
ML179 is a potent and selective inverse agonist of liver receptor homolog-1 (LRH1, NR5A2) with IC50 of 320 nM. | |||
TP1444 | Magainin 2 | Antibacterial , Antibiotic , Antifungal | |
Magainin II is a member of the antimicrobial peptides family | |||
T0396 | Pipemidic acid | Acido pipemidico | Antibacterial , Antibiotic |
Pipemidic acid (Acido pipemidico), a new antibacterial agent, inhibits the activity of Pseudomonas aeruginosa. | |||
T4123 | LYN-1604 | LYN1604 | Apoptosis , Autophagy |
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis. | |||
T9066 | Merafloxacin | CI 934 | SARS-CoV |
Merafloxacin (CI 934) is a fluoroquinolone antibacterial, which was also identified as a 1 PRF inhibitor of SARS-CoV-2. | |||
T13044 | Mevociclib | SY-1365 | CDK |
Mevociclib (SY-1365) is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors. | |||
T19664 | ON1231320 | GBO-006 | Apoptosis , PLK |
ON1231320 (GBO-006) is a Polo-like kinase 2 (PLK2) inhibitor. | |||
T40475 | Ceftobiprole medocaril | BAL5788 | Antibacterial |
Ceftobiprole medocaril (BAL5788) is the parenteral prodrug of Ceftobiprole. Ceftobiprole is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA). | |||
T6797 | Telaglenastat | CB 839,CB839,CB-839 | transporter , Glutaminase , Autophagy |
Telaglenastat (CB 839) (IC50 of 24 nM), an effective, specific, and oral inhibitor, which is bioavailable glutaminase, for recombinant human GAC. | |||
T10608 | BRD5648 | (R)-BRD0705 | GSK-3 |
T19794 | Temafloxacin | Omniflox | Antibiotic |
Temafloxacin (Omniflox) is an antibiotic and antimycobacterial agent. It used to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections. | |||
T0199 | Cephradine | Anspor,Cephradin,Velosef,SQ-11436,Sefril | TOPK , Antibacterial , Antibiotic |
Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. | |||
T1000L | Chlorhexidine diacetate | Hibitane diacetate,Chlorhexidine Acetate,Bactigras | CAT , Antibacterial , Antibiotic , Antifection |
Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. | |||
T9317 | TAK-041 | NBI-1065846 | GPR |
TAK-041 (NBI-1065846) is a potent and selective GPR139 agonist. | |||
T3125 | Amikacin sulfate | Amikacin Sulfate Salt | ribosome , Antibacterial , Antibiotic |
Amikacin sulfate is a broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and ototoxic like the other aminoglycoside antibiotics. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T2P2937 | Nonacosane | Others , Antibacterial | |
Nonacosane is a straight-chain alkane comprising of 29 carbon atoms. It has a role as a plant metabolite and a volatile oil component. | |||
T8126 | Cefodizime Sodium | Others , Antibacterial , Antibiotic | |
Cefodizime Sodium is a third generation cephalosporin antibiotic, has broad-spectrum activity | |||
T4S0867 | Pogostone | DHELWANGIN | Apoptosis , Antibacterial , Autophagy |
1. Pogostone (DHELWANGIN) possesses potent anti-bacterial and anti-fungal activities, such as gram negative bacteria , gram positive bacteria, Escherichia coli. 2. Pogostone exhibits an immunosuppressive property by dire... | |||
T0895 | Oxytetracycline | Terramycin | ribosome , Endogenous Metabolite , Antibacterial , Antibiotic , HSV |
Oxytetracycline (Terramycin) is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions. | |||
T8118 | Bekanamycin | Kanamycin B | Antibacterial , Antibiotic |
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic. | |||
T0224 | Meropenem | SM 7338 | Others , Antibacterial , Antibiotic |
Meropenem (SM 7338) is a carbapenem antibiotic with broad spectrum of activity that is administered intravenously and used for severe bacterial infections due to sensitive agents. Meropenem is a common cause of mild tran... | |||
TCS1554 | Trans-Benzylideneacetone | Acetocinnamone | Phospholipase |
trans-Benzylideneacetone (Acetocinnamone) is used in various synthetic preparations. | |||
TN2011 | Ombuoside | Ombuin-3beta-rutinoside | Antibacterial |
Ombuoside (Ombuin-3beta-rutinoside) has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.Ombuoside is a glycoside ombuoside isolated from Gynostemma penta... | |||
T8160 | EGCG Octaacetate | Others , Antibacterial | |
EGCG Octaacetate, a prodrug of EGCG, is utilized to enhance the stability and bioavailability of EGCG in vivo. It has high efficacy, bioavailability, anti-oxidation, and anti-angiogenesis capacities. | |||
T6624 | Oxytetracycline Dihydrate | Terramycin Dihydrate | Others , Endogenous Metabolite , Antibacterial , Antibiotic , HSV |
Oxytetracycline Dihydrate (Terramycin Dihydrate) is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins. | |||
T19808 | 5-Bromo-5-nitro-1,3-dioxane | Bronidox | Others , Antibacterial , Antifungal |
5-Bromo-5-nitro-1,3-dioxane (Bronidox) is an antimicrobial compound that works by inhibiting enzyme activity in bacteria. | |||
T0788 | Spectinomycin dihydrochloride | Spectinomycin 2HCl,Actinospectacin | ribosome , Antibacterial , Antibiotic |
Spectinomycin dihydrochloride (Actinospectacin) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea. | |||
T21430 | Oxytetracycline Hydrochloride | Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin | Antiviral , Endogenous Metabolite , Antibacterial , HSV |
Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resultin... | |||
TQ0251 | (Z)-2-decenoic acid | (Z)-dec-2-enoic acid,cis-2-Decenoic acid,cis-dec-2-enoic acid | Others |
(Z)-2-decenoic acid (cis-dec-2-enoic acid) is an unsaturated short-chain fatty acid secreted by Pseudomonas aeruginosa. It can induce a dispersion response in biofilms formed by gram-negative and gram-positive bacteria. ... | |||
T4984 | Cefozopran hydrochloride | SCE-2787 hydrochloride | Antifungal |
Cefozopran hydrochloride (SCE-2787 hydrochloride) is a fourth-generation cephalosporin. is a cell wall biosynthesis inhibitor with a broad spectrum of activity against Gram-positive and Gram-negative bacteria. | |||
T5757 | Loganetin | Antibacterial | |
Loganetin, a non-toxic natural product, shows antibacterial activity against multidrug-resistant Gram-negative infections. | |||
T28764 | SF2312 | SF-2312,SF 2312 | Glucokinase , Antibacterial |
SF2312 is a natural phosphonate antibiotic produced by Actinobacillus microsporus and is a potent inhibitor of the glycolytic enzyme enolase.SF2312 has antimicrobial activity and inhibits bacterial growth against both Gr... | |||
T40583 | N-(3-Oxotetradecanoyl)-DL-homoserine lactone | 3-Oxo-C14-AHL,N-(3-Oxotetradecanoyl)-DL-homoserine lactone | |
N-(3-Oxotetradecanoyl)-DL-homoserine lactone, part of the N-Acyl homoserine lactone (AHL) family derived from gram-negative bacteria, serves as a quorum sensing (QS) signaling molecule. | |||
T8247 | (+)-Aromadendrene | Anti-infection | |
(+)-Aromadendrene is a natural product that has significant antibacterial activity against the Gram-positive and Gram-negative bacteria. | |||
T4889 | 2,6-Diaminoheptanedioic acid | Others , Endogenous Metabolite | |
Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall. DAPA is incorporated or integrated into peptidoglycan of gram negative bacteria and is the attachment... | |||
T8062 | Cefazedone | Refosporen | Others , Antibacterial , Antibiotic |
Cefazedone (Refosporen) is a semisynthetic first-generation cephalosporin with activity against Gram-positive and Gram-negative bacteria[1]. | |||
T1306 | Norfloxacin | MK-0366 | DNA gyrase , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic |
Norfloxacin (MK-0366)(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. | |||
T5037 | Midecamycin | Antibiotic SF-837,Turimycin P3,Medecamycin A1,Rubimycin,Platenomycin B1,Espinomycin A | Antibacterial , Antibiotic |
Midecamycin (Medecamycin A1), an acetoxy-substituted macrolide antibiotic, has effective on gram-positive and gram-negative bacteria acts by inhibiting bacterial protein synthesis. | |||
T8302 | Ceftiofur | Antibacterial , Antibiotic | |
Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive/negative, anaerobic and aerobic bacteria encountered by domestic animals. | |||
T3501 | Colistimethate Sodium | Colistin-1,3,5,9-tetramethanesulfonic A acid | Others |
Colistin-1,3,5,9-tetramethanesulfonic A acid is used for the treatment of serious infections due to selected aerobic Gram-negative pathogens in patients with limited treatment options. | |||
TN6764 | Simmondsin | Others | |
Simmondsin is a natural product from Simmondsia chinensis -- jojoba. It reduced food intake and body weight without apparent negative effects in rats. | |||
T2896 | Alantolactone | helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor | Apoptosis , STAT , TGF-beta/Smad |
Alantolactone (Inula camphor)(Alant camphor), a sesquiterpene lactone, has potential activity against triple-negative breast Y MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3... | |||
T8148 | Mupirocin calcium hydrate | Mupirocin calcium | Others , Antibacterial , Antibiotic |
Mupirocin calcium hydrate is an antibiotic produced by Pseudomonas fluorescens, showed a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria | |||
T1679 | Thiostrepton | Thiactin,Bryamycin,Alaninamide | DNA/RNA Synthesis , Antibacterial , Antibiotic |
Thiostrepton (Alaninamide) is a one of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastitis caused by gram-negative organisms and in de... | |||
TN6750 | 2-tert-Butyl-1,4-benzoquinone | Nrf2 | |
2-tert-Butyl-1,4-benzoquinone (TBQ), an electrophilic metabolite of butylated hydroxyanisole (BHA), causes activation of Nrf2 together with S-arylation of its negative regulator Keap1 in RAW264.7 cells. | |||
TN6779 | Clausine E | Others | |
Clausine E is an inhibitor of fat mass and obesity-associated protein (FTO) demethylase activity. The binding of Clausine E to FTO was driven by positive entropy and negative enthalpy changes. | |||
T7979 | 2-Hydroxychalcone | 2-(2-Hydroxybenzal)Acetophenone | Apoptosis , BCL , Others , NF-κB |
2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated.It can inhibit invasion of triple negative breast cancer cells. | |||
T0814L | Ampicillin | Amcill,D-(-)-α-Aminobenzylpenicillin,Aminobenzylpenicillin,Ampicillin acid | Antibacterial , Antibiotic |
Ampicillin (Aminobenzylpenicillin) is a semi-synthetic penicillin belonging to the β-lactam group of antibiotics. Ampicillin has bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria. | |||
T5274 | D-(+)-Phenyllactic acid | D-3-Phenyllactic acid | Endogenous Metabolite , Antibacterial |
D-(+)-Phenyllactic acid (D-3-Phenyllactic acid), an antibacterial compound produced by Geotrichum candidum, effectively inhibits various Gram-positive and Gram-negative bacteria originating from humans and food products[... | |||
T5S0814 | Berberine hydrogen sulphate | Berberine Bisulfate,Umbellatine Sulfate | Antibacterial |
Berberine hydrogen sulphate (Umbellatine Sulfate) , an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria,... | |||
T2S2335 | Dehydroevodiamine | DHED | Others , NF-κB , COX , PGE Synthase , NO Synthase |
Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood fl... | |||
T8262 | Fosfomycin sodium | Fosfomycin Disodium | Antibacterial , Antibiotic |
Fosfomycin sodium is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an e... | |||
T3418 | Demethylzeylasteral | Demethylzeylasteral (T-96) | Apoptosis , UGT |
Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities. It inhibits the invasion of triple-negative breast cancer by blocking the TGF-β signal... | |||
T1313 | Nitrofurantoin | Furadantine,Macrodantin,Furadonine | Antibacterial , Antibiotic |
Nitrofurantoin (Furadantine), an antibiotic, inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoi... | |||
T6S1683 | Demethoxycurcumin | Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin | Apoptosis , Antioxidant , Antibacterial , Autophagy |
1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic e... | |||
T12830 | Sapienic acid sodium | Antibacterial | |
Sapienic acid sodium is a fatty acid commonly. It has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. | |||
T4592 | TOMATIDINE HYDROCHLORIDE | Tomatidine,Tomatidine HCl | Others , NF-κB , JNK , Autophagy |
Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway. May be used as a negative control for Cyclopamine and KAAD-Cyclopamine. Tomatid... | |||
T5803 | D(-)-Tartaric acid | Others | |
D(-)-Tartaric acid found in many plants, particularly tamarinds and grapes,it is used to generate carbon dioxide through interaction with sodium bicarbonate following oral administration. Carbon dioxide extends the stoma... | |||
T2946 | Tanshinone IIA sulfonate sodium | Tanshinone IIA sulfonate,Sodium Tanshinone IIA sulfonate,Tanshinone IIA sodium sulfonate,sodium | CaMK , P450 , Calcium Channel |
Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor... | |||
T1100 | Polymyxin B Sulfate | Aerosporin,PMB,Polymyxin B sulphate,Polymyxin B sulfate (1404-26-8 free base),Poly-RX | Antibacterial , Antibiotic |
Polymyxin B Sulfate (Poly-RX) is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Po... | |||
T21771 | Pyoluteorin | Antibiotic | |
Pyoluteorin is an antibiotic that inhibits Oomycete fungi, including the plant pathogen Pythium ultimum, and suppresses plant diseases caused by this fungus. Pyoluteorin induces human triple-negative breast cancer MDA-MB... | |||
T2989 | 4-Hydroxybenzoic acid | p-hydroxybenzoic acid,para-Hydroxybenzoic acid,PHBA,4-hydroxybenzoate | Endogenous Metabolite , Antibacterial |
4-Hydroxybenzoic acid (4-hydroxybenzoate) is a monohydroxybenzoic acid, a phenolic derivative of benzoic acid. It is a white crystalline solid that is slightly soluble in water and chloroform but more soluble in polar or... | |||
TN1545 | D-Tyrosine | Tyrosinase | |
D-Tyrosine, the D-isomer of tyrosine, acts as a negative regulator of melanin synthesis by inhibiting tyrosinase activity. Furthermore, D-Tyrosine also inhibits biofilm formation and induces the self-dispersal of biofilm... | |||
T0958 | Penicillin G sodium salt | Penicillin G Sodium,Benzylpenicillin sodium salt,Benzylpenicillin Sodium | GABA Receptor , Antibacterial , Antibiotic |
Penicillin G sodium(Benzylpenicillin sodium) salt is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-posit... | |||
T2O2731 | L-Aspartic acid | Aspatofort,Asparagic acid | Others , Endogenous Metabolite |
L-Aspartic acid (Aspatofort) is a non-essential amino acid in humans, L-Aspartic acid has an overall negative charge and plays an important role in the synthesis of other amino acids and in the citric acid and urea cycle... | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPK-01452 | HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ... | |||
TMPJ-00700 | GADD45B Protein, Human, Recombinant (His) | Human | E. coli |
Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of g... | |||
TMPY-03118 | ORM2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
ORM2 belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, ... | |||
TMPY-02204 | LBP Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP b... | |||
TMPY-02904 | TLR4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans... | |||
TMPJ-00412 | VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ... | |||
TMPY-02219 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) | H1N1 | E. coli |
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N... | |||
TMPH-02592 | CTHRC1 Protein, Mouse, Recombinant (aa 33-245, His) | Mouse | HEK293 Cells |
May act as a negative regulator of collagen matrix deposition. | |||
TMPH-02593 | CTHRC1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
May act as a negative regulator of collagen matrix deposition. | |||
TMPH-00788 | PYP Protein, Halochromatium salexigens, Recombinant (His) | Halochromatium salexigens | E. coli |
Photoactive blue light protein. Probably functions as a photoreceptor for a negative phototaxis response. | |||
TMPH-02886 | SOST Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. | |||
TMPY-02908 | BPI Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Bactericidal/permeability-increasing protein is a member of the BPI/LBP/Plunc superfamily and BPI/LBP family. It is a cationic protein which can be detected in the azurophilic granule and on the surface of polymorphonucl... | |||
TMPH-02156 | SOCS1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Through ... | |||
TMPH-01123 | CTHRC1 Protein, Human, Recombinant (aa 31-243, hFc) | Human | HEK293 Cells |
May act as a negative regulator of collagen matrix deposition. CTHRC1 Protein, Human, Recombinant (aa 31-243, hFc) is expressed in HEK293 mammalian cells with C-hFC tag. The predicted molecular weight is 52 kDa and the a... | |||
TMPH-01415 | MSTN Protein, Human, Recombinant (His) | Human | E. coli |
Acts specifically as a negative regulator of skeletal muscle growth. MSTN Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.4 kDa and the a... | |||
TMPH-02773 | Lysozyme C-2 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Lyz2 is active against a range of Gram-posi... | |||
TMPH-00085 | SIZ1 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
E3 SUMO protein ligase involved in regulation processes. Mediates SUMO/ attachment to PHR1, a MYB transcriptional activator controlling the phosphate deficiency responses. Functions as an upstream negative regulator of s... | |||
TMPH-00574 | Adenylate cyclase Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the formation of the second messenger cAMP from ATP. Its transcript is probably degraded by endoribonuclease LS (rnlA), decreasing cAMP levels and the negative regulator Crp-cAMP, which then induces its own tra... | |||
TMPH-00963 | Ataxin-2 Protein, Human, Recombinant (His) | Human | E. coli |
Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. Ataxin-2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. ... | |||
TMPJ-01443 | HChFc2 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Host cell factor 2(HCFC2) is a cytoplasmic protein. It contains 2 fibronectin type-III domains.HCFC2 binds KMT2A/MLL1, as component of the MLL1/MLL complex.Hcfc2 negative regulation of transcription from RNA polymerase I... | |||
TMPH-00230 | Cathelicidin-6 Protein, Bovine, Recombinant (His & SUMO) | Bovine | E. coli |
Exerts a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, and fungi. Cathelicidin-6 Protein, Bovine, Recombinant (His & SUMO) is expre... | |||
TMPH-02267 | AGTRAP Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decr... | |||
TMPH-03611 | Sso7d Protein, Sulfolobus solfataricus, Recombinant (His & SUMO) | Sulfolobus solfataricus | E. coli |
Can constrain negative DNA supercoils. May be involved in maintaining the integrity of the genome at high temperature. Stimulates the Holliday junction cleavage activity of Hjc. Sso7d Protein, Sulfolobus solfataricus, Re... | |||
TMPH-01316 | ECM1 Protein, Human, Recombinant (GST & His & Myc) | Human | E. coli |
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. ECM1 Protein, Human, ... | |||
TMPH-01772 | DEFA1 Protein, Human, Recombinant (GST) | Human | E. coli |
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing thei... | |||
TMPH-03100 | PMAP-23 Protein, Pig, Recombinant (His & SUMO) | Sus scrofa (Pig) | E. coli |
Exerts antimicrobial activity against both Gram-positive and negative bacteria at concentrations of 2-16 micro molar. Its activity appears to be mediated by its ability to damage bacterial membranes. PMAP-23 Protein, Pig... | |||
TMPH-01825 | NOTUM Protein, Human, Recombinant (His) | Human | E. coli |
Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient bindin... | |||
TMPY-02264 | LRIG1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a tumor suppressor and a negative regulator of several receptor tyrosine kinases. Leucine-rich repeats and immunoglobulin-like domains containing protein ... | |||
TMPH-00361 | Beta-mammal toxin Cn2 Protein, Centruroides noxius, Recombinant (His) | Centruroides noxius | P. pastoris (Yeast) |
Mammal beta-toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the activation voltage to more negative potentials. This toxin is active against mammals. Beta-mammal toxin Cn2 Protein, Centruro... | |||
TMPJ-00223 | SLAMF1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in... | |||
TMPH-00538 | Epstein-Barr virus (strain GD1) EBNA3 Protein (His & Myc) | EBV | E. coli |
Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promo... | |||
TMPH-00537 | Epstein-Barr virus (strain B95-8) EBNA3 Protein (His & Myc) | EBV | E. coli |
Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promo... | |||
TMPJ-00306 | SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre... | |||
TMPH-01610 | LINGO1 Protein, Human, Recombinant (His) | Human | E. coli |
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of ... | |||
TMPJ-01245 | UCMA Protein, Human, Recombinant | Human | E. coli |
C10orf49 is a secreted protein which encoded by the UCMA gene. It is a member of the UCMA family. C10orf49 is predominantly expressed in resting chondrocytes. It may be involved in the negative control of osteogenic diff... | |||
TMPK-01001 | RNF43 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 i... | |||
TMPH-03145 | Thanatin Protein, Podisus maculiventris, Recombinant (His & KSI) | Podisus maculiventris | E. coli |
Insect defense peptide with a broad spectrum of activity against Gram-positive and Gram-negative bacteria and fungi. No activity against S.aureus. Stops respiration in bacteria but does not permeabilize their inner membr... | |||
TMPJ-00305 | SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His) | Cynomolgus | HEK293 Cells |
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre... | |||
TMPK-01483 | HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01482 | HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01519 | HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01515 | HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01293 | SOST Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of ... | |||
TMPJ-01182 | SIRP alpha Protein, Mouse, Recombinant (MIgG2a) | Mouse | HEK293 Cells |
SIRPα is a type I transmembrane glycoprotein.It contains two Ig-like C1-type domains and one Ig-like V-type domain. Mouse SIRP alpha ECD shares 61%, 75%, 62%, 61%, and 59% aa sequence identity with human, rat, equine, bo... | |||
TMPK-01520 | HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01521 | HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01484 | HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01477 | HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01436 | HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
TMPK-01478 | HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ... | |||
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カタログ番号 | 製品名 | ||
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L2191 | Anti-Breast Cancer Compound Library | 1939 compounds | |
A unique collection of 1939 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study; | |||
L2550 | Glutamine Metabolism Compound Library | 565 compounds | |
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... |