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カタログ番号	製品名	別名	ターゲット
T6093	AZD-7762	AZD7762	Chk
	AZD-7762, an effective and specific inhibitor of Chk1（IC50=5 nM）, is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.		Chk
T5697	BMS-1166		PD-1/PD-L1
	BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.		PD-1/PD-L1
T7080	CCT245737	SRA737	Chk
	CCT245737 (SRA737) is an orally active and selective Chk1 inhibitor (IC50: 1.3 nM); CCT245737 shows much less activity against Chk2 (IC50: 2440 nM).		Chk
T21331	SAR-020106		Chk
	SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme.		Chk
T10565	BMS-1001 hydrochloride		PD-1/PD-L1
	BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activat...		PD-1/PD-L1
T2517	SCH900776	MK 8776,MK-8776	Chk , CDK
	SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.		Chk , CDK
T6350	CHIR-124	CHIR124,CHIR 124	Apoptosis , GSK-3 , FLT , Chk , PDGFR , Src
	CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.		Apoptosis , GSK-3 , FLT , Chk , PDGFR , Src
T6084	Rabusertib	LY2603618,IC-83	Chk , PDK , Autophagy
	Rabusertib (IC-83) is an inhibitor of the cell cycle checkpoint kinase 1 (chk1) with potential chemopotentiating activity. Rabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cance...		Chk , PDK , Autophagy
T2033	BML-277	C 3742,Chk2 Inhibitor II,BML 277	Apoptosis , Chk
	BML-277 (C 3742) is a selective checkpoint kinase 2 (Chk2) inhibitor.		Apoptosis , Chk
T7300	GDC-0575	ARRY-575,RG7741	Chk
	GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).		Chk
T4327	Prexasertib dihydrochloride	LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368	Apoptosis , Chk , S6 Kinase
	Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively.		Apoptosis , Chk , S6 Kinase
T4310	Prexasertib	LY2606368	Apoptosis , Chk
	Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.		Apoptosis , Chk
T6028	PF 477736	PF 00477736,PF-477736,PF-736,PF-00477736,PF477736	c-Fms , VEGFR , FGFR , FLT , c-RET , Chk , CDK , Src , Aurora Kinase
	PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.
T2077	Adavosertib	AZD1775,MK-1775,Adavosertib (MK-1775)	Wee1
	Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.		Wee1
T9252	LY2880070		Chk
	LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.		Chk
T10792L	CHK1-IN-4 hydrochloride	CHK1-IN-4 hydrochloride（2120398-41-4 Free base）	Chk
	CHK1-IN-4 hydrochloride is a potent inhibitor of checkpoint kinase 1 (chk1). CHK1-IN-4 hydrochloride potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 hydrochloride has anti-tumor activity.		Chk
T10791	CHK1-IN-3		Chk
	CHK1-IN-3 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 0.4 nM).		Chk
T10406	Tuvusertib	M1774,ATR inhibitor 1	Apoptosis , ATM/ATR , Others , Chk
	Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 µΜ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks...		Apoptosis , ATM/ATR , Others , Chk
T6931	PD0166285	PD-166285	Apoptosis , Wee1 , Chk
	PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.		Apoptosis , Wee1 , Chk
T14765	BOS-172722		Kinesin
	BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).		Kinesin
T9907	Nivolumab		PD-1/PD-L1
	Nivolumab (anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1PD-1PCD-1) with immune ...		PD-1/PD-L1
T9906	Ipilimumab		Others
	Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor.		Others
T3700	SCH900776 (S-isomer)	MK-8776 S-isomer,SCH900776 S-isomer	Chk , CDK
	SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM). It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 16...		Chk , CDK
T2440	IC261	SU-5607	Apoptosis , Casein Kinase , CDK
	IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.		Apoptosis , Casein Kinase , CDK
T35362	NSC622608		Others
	NSC622608 is a small-molecule ligand for V-domain Ig suppressor of T-cell activation (VISTA) which is an immune checkpoint that affects the ability of T-cells to attack tumors.		Others
T77471	Tinurilimab	BAY 1834942
	Tinurilimab (Bay 1834942) is a monoclonal antibody that targets and inhibits CEACAM6, an immune checkpoint regulator. Tinurilimab can be used in studies about effector T-cells against tumors.
T76750	Cemiplimab	REGN-2810,SAR-439684	Others
	Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cance...		Others
T6543	Indoximod	NLG-8189,Indoximod (NLG-8189）,1-Methyl-D-tryptophan	Indoleamine 2,3-Dioxygenase (IDO)
	Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan...		Indoleamine 2,3-Dioxygenase (IDO)
T15576	Indibulin	ZIO 301,D 24851	Apoptosis , Microtubule Associated
	Indibulin (D 24851) is a synthetic small molecule with antimitotic and potential antineoplastic activities.Indibulin an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neu...		Apoptosis , Microtubule Associated
T76691	Monalizumab		IFNAR , Chk
	Monalizumab is a novel immune checkpoint inhibitor targeting natural killer cell population 2A (NKG2A). Monalizumab is a humanized monoclonal antibody against NKG2A that induces IFN-γ production, thereby activating natur...		IFNAR , Chk
T77761	BMS-502		Others
	BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ that induces immune responses in human and mouse T cells and blocks intracellular checkpoint signaling in T cells. BMS-502 stimulates immune respo...		Others
T27407	GDC0575 monohydrochloride	ARRY-575,GDC-0575,GDC 0575,ARRY575,GDC0575	Chk
	GDC0575 monohydrochloride (ARRY575) is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2 nM. GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells by...		Chk
T23447	TCS 2312		Others
	checkpoint kinase 1 (chk1) inhibitor		Others
T6093L	AZD7762 HCl	AZD7762 Hydrochloride
	AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and enhancing DNA-targeted treatment.
T23865	CCT-271850	MPS1-IN-77,MPS1IN77,CCT271850,CCT 271850,MPS1 IN 77
	CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.
T24768	SC-203885	SC 203885,SC203885
	SC-203885 is a checkpoint kinase 2 inhibitor.
T17223	VER-00158411		Chk
	VER-00158411 is a checkpoint kinase 1 and CHK2 inhibitor (IC50: 4.4 nM and 4.5 nM, respectively).		Chk
T10790	CHK1-IN-2		Chk
	CHK1-IN-2 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 6 nM).		Chk
T69091	CBP501
	CBP501 is a peptide with G2 checkpoint-abrogating activity. G2 checkpoint inhibitor CBP501 inhibits multiple serine/threonine kinases, including MAPKAP-K2, C-Tak1, and CHK1, that phosphorylate serine 216 of the dual-spec...
T69163	BML277 Acid
	BML277 Acid is a metabolite of BML277 which is a selective checkpoint kinase 2 inhibitor.
T10792	CHK1-IN-4		Chk
	CHK1-IN-4 is a potent inhibitor of checkpoint kinase 1 (chk1) and potently inhibits chk1 phosphorylation in the tumor cells with anti-tumor activity.		Chk
T68895	CBP-93872
	CBP-93872 is a G2 checkpoint inhibitor. CBP-93872 specifically abrogates the DNA double-stranded break (DSB)-induced G2 checkpoint through inhibiting maintenance. CBP-93872 is an inhibitor of maintenance of the DSB-speci...
T14904	CCT244747		Chk
			Chk
T70553	CCT245737(S)
	CCT245737(S) is a highly selective oral checkpoint kinase 1 (CHK1) inhibitor.
T70286	BMS-37
	BMS-37 is a novel inhibitor of PD-1/PD-L1 immune checkpoint.
T22957	LY2606368 HCl (1234015-52-1 free base)	LY2606368 HCl	Others
	LY2606368 HCl is a selective ATP competitive inhibitor of checkpoint kinase 1 (IC50: 1.5nM in SW1990 cells).		Others
T37098	Chk1-IN-5	Chk1-IN-5
	Chk1-IN-5 is a highly effective inhibitor of checkpoint kinase 1 (Chk1), which hinders the phosphorylation of Chk1 and effectively suppresses tumor growth in a colon cancer xenograft model[1].
TP1076	AUNP-12	NP-12
	AUNP-12, a new immune checkpoint modulator, is an inhibitor of the PD-1 pathway.
T10272	AHR antagonist 5		Others
	AHR antagonist 5 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 39; IC50 < 0.5 μΜ). It significantly inhibits tumor growth combined with checkpoint inhibitor anti-PD-1.		Others
T10407	Gartisertib	ATR inhibitor 2	ATM/ATR
	ATR inhibitor 2 is an orally active, ATP-competitive, and selective ATR inhibitor (Ki <150 pM) with antitumor activity. ATR inhibitor 2 potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylati...		ATM/ATR

Compounds

BMS-1001 hydrochloride

Synonym: MK 8776,MK-8776

Target: Chk, CDK

CHIR-124

T6350

Synonym: CHIR124,CHIR 124

Target: Apoptosis, GSK-3, FLT, Chk, PDGFR, Src

Rabusertib

T6084

Synonym: LY2603618,IC-83

Target: Chk, PDK, Autophagy

BML-277

T2033

Synonym: C 3742,Chk2 Inhibitor II,BML 277

Target: Apoptosis, Chk

GDC-0575

T7300

Synonym: ARRY-575,RG7741

Target: Chk

Prexasertib dihydrochloride

T4327

Synonym: LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368

Target: Apoptosis, Chk, S6 Kinase

Prexasertib

T4310

Synonym: LY2606368

Target: Apoptosis, Chk

PF 477736

T6028

Synonym: PF 00477736,PF-477736,PF-736,PF-00477736,PF477736

Target: c-Fms, VEGFR, FGFR, FLT, c-RET, Chk, CDK, Src, Aurora Kinase

Adavosertib

T2077

Synonym: AZD1775,MK-1775,Adavosertib (MK-1775)

CHK1-IN-4 hydrochloride

T10792L

Synonym: CHK1-IN-4 hydrochloride（2120398-41-4 Free base）

Synonym: M1774,ATR inhibitor 1

Target: Apoptosis, ATM/ATR, Others, Chk

PD0166285

T6931

Synonym: PD-166285

Target: Apoptosis, Wee1, Chk

Synonym: MK-8776 S-isomer,SCH900776 S-isomer

Target: Apoptosis, Casein Kinase, CDK

Synonym: REGN-2810,SAR-439684

Target: Others

Indoximod

T6543

Synonym: NLG-8189,Indoximod (NLG-8189）,1-Methyl-D-tryptophan

Target: Indoleamine 2,3-Dioxygenase (IDO)

Indibulin

T15576

Synonym: ZIO 301,D 24851

Target: Apoptosis, Microtubule Associated

GDC0575 monohydrochloride

T27407

Synonym: ARRY-575,GDC-0575,GDC 0575,ARRY575,GDC0575

Synonym: AZD7762 Hydrochloride

Target:

CCT-271850

T23865

Synonym: MPS1-IN-77,MPS1IN77,CCT271850,CCT 271850,MPS1 IN 77

Target:

SC-203885

T24768

Synonym: SC 203885,SC203885

LY2606368 HCl (1234015-52-1 free base)

T22957

Synonym: LY2606368 HCl

Synonym: ATR inhibitor 2

Target: ATM/ATR

カタログ番号	製品名	ターゲット
TN3724	Cryptomoscatone D2	p53
	Cryptomoscatone D2 is a highly efficacious inhibitor of the G(2) checkpoint, and G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis.	p53
TN3721	Cryptofolione	Antifection
	Z-Cryptofolione and Cryptomoscatone D2 as highly efficacious inhibitors of the G(2) checkpoint, G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis. Cryptofolione shows modera...	Antifection

天然物製品

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04368	Chk1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	CHK1 / CHEK1 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily. It is a member of checkpoint kinases (Chks). Chks Checkpoint kinases (Chks)...
TMPY-04433	Chk1 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	CHK1 / CHEK1 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily. It is a member of checkpoint kinases (Chks). Chks Checkpoint kinases (Chks)...
TMPY-04435	CHEK2 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by CHEK2 gene is a cell cycle checkpoint regulator and putativ...
TMPY-04681	CHEK2 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by CHEK2 gene is a cell cycle checkpoint regulator and putativ...
TMPY-03947	CD48 Protein, Human, Recombinant (hFc)	Human	HEK293
	Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD4...
TMPY-03203	CD40 Protein, Rat, Recombinant (His)	Rat	HEK293
	CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-01155	PD-L1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-04949	PD-L1 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-05208	PD-L1 Protein, Human, Recombinant	Human	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-00996	PD-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-05079	PD-1 Protein, Human, Recombinant (mFc)	Human	HEK293
	Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-05791	CD155/PVR Protein, Mouse, Recombinant (mFc)	Mouse	HEK293
	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-00699	CD155/PVR Protein, Human, Recombinant (hFc)	Human	HEK293
	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-00237	PD-L1 Protein, Canine, Recombinant (hFc)	Canine	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-04343	PD-L1 Protein, Human, Recombinant (His)	Human	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-05395	PD-1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-04898	PD-1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-06021	CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His)	Human,Cynomolgus,Rhesus	HEK293
	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and ...
TMPY-04064	B7-H3 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-04262	B7-H3 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-02031	B7-H3 Protein, Human, Recombinant (His)	Human	HEK293
	B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-04348	CTLA-4 Protein, Human, Recombinant (His)	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-05957	CD40 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-01181	CD40 Protein, Human, Recombinant (His)	Human	HEK293
	CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-04345	PD-L1 Protein, Rat, Recombinant (His)	Rat	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-03670	PD-L1 Protein, Cynomolgus/Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-05354	CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and ...
TMPY-00033	4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)	Human	HEK293
	4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as de...
TMPY-05815	PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated	Canine	HEK293
	Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-00897	PD-1 Protein, Human, Recombinant (His)	Human	HEK293
	Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-04342	PD-1 Protein, Canine, Recombinant (His)	Canine	HEK293
	Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-05260	PD-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-01604	CTLA-4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-01180	CD86 Protein, Human, Recombinant (His)	Human	HEK293
	CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
TMPY-04123	CEACAM1 Protein, Human, Recombinant (His & hFc)	Human	HEK293
	The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and diffe...
TMPY-04824	CTLA-4 Protein, Human, Recombinant	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-01612	CD155/PVR Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-01386	CD155/PVR Protein, Human, Recombinant (His)	Human	HEK293
	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-01423	OX40/TNFRSF4 Protein, Human, Recombinant (His)	Human	HEK293
	OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea...
TMPY-00674	B7-1 Protein, Human, Recombinant	Human	HEK293
	The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B c...
TMPY-04957	PD-L2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-01941	CD28 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and ...
TMPY-01672	ICOS ligand Protein, Human, Recombinant (His)	Human	HEK293
	Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains an...
TMPY-04951	CD27/TNFRSF7 Protein, Human, Recombinant (His), Biotinylated	Human	Baculovirus-Insect Cells
	CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a typ...
TMPY-05641	B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-03401	CD27/TNFRSF7 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a typ...
TMPY-02632	SIRP alpha Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-05827	PD-L2 Protein, Human, Recombinant (mFc)	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-02022	CD40 Ligand Protein, Human, Recombinant (hFc)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-05322	B7-H4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express...
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Chk1 Protein, Human, Recombinant (GST)

TMPY-04368

Species: Human

Expression System: Baculovirus-Insect Cells

Chk1 Protein, Mouse, Recombinant (His & GST)

TMPY-04433

Species: Mouse

Expression System: Baculovirus-Insect Cells

CHEK2 Protein, Mouse, Recombinant (His & GST)

TMPY-04435

Species: Mouse

Expression System: Baculovirus-Insect Cells

CHEK2 Protein, Human, Recombinant (GST)

TMPY-04681

Species: Human

Expression System: Baculovirus-Insect Cells

CD48 Protein, Human, Recombinant (hFc)

TMPY-03947

Species: Human

Expression System: HEK293

CD40 Protein, Rat, Recombinant (His)

TMPY-03203

Species: Rat

Expression System: HEK293

PD-L1 Protein, Mouse, Recombinant (His)

TMPY-01155

Species: Mouse

Expression System: HEK293

PD-L1 Protein, Human, Recombinant (His), Biotinylated

TMPY-04949

Species: Human

Expression System: HEK293

PD-L1 Protein, Human, Recombinant

TMPY-05208

Species: Human

Expression System: HEK293

PD-1 Protein, Mouse, Recombinant (His)

TMPY-00996

Species: Mouse

Expression System: HEK293

PD-1 Protein, Human, Recombinant (mFc)

TMPY-05079

Species: Human

Expression System: HEK293

CD155/PVR Protein, Mouse, Recombinant (mFc)

TMPY-05791

Species: Mouse

Expression System: HEK293

CD155/PVR Protein, Human, Recombinant (hFc)

TMPY-00699

Species: Human

Expression System: HEK293

PD-L1 Protein, Canine, Recombinant (hFc)

TMPY-00237

Species: Canine

Expression System: HEK293

PD-L1 Protein, Human, Recombinant (His)

TMPY-04343

Species: Human

Expression System: HEK293

PD-1 Protein, Mouse, Recombinant (hFc)

TMPY-05395

Species: Mouse

Expression System: HEK293

PD-1 Protein, Human, Recombinant (hFc)

TMPY-04898

Species: Human

Expression System: HEK293

CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His)

TMPY-06021

Species: Human,Cynomolgus,Rhesus

Expression System: HEK293

B7-H3 Protein, Mouse, Recombinant (His)

TMPY-04064

Species: Mouse

Expression System: HEK293

B7-H3 Protein, Human, Recombinant (His), Biotinylated

TMPY-04262

Species: Human

Expression System: HEK293

B7-H3 Protein, Human, Recombinant (His)

TMPY-02031

Species: Human

Expression System: HEK293

CTLA-4 Protein, Human, Recombinant (His)

TMPY-04348

Species: Human

Expression System: HEK293

CD40 Protein, Mouse, Recombinant (His)

TMPY-05957

Species: Mouse

Expression System: HEK293

CD40 Protein, Human, Recombinant (His)

TMPY-01181

Species: Human

Expression System: HEK293

PD-L1 Protein, Rat, Recombinant (His)

TMPY-04345

Species: Rat

Expression System: HEK293

PD-L1 Protein, Cynomolgus/Rhesus, Recombinant (His)

TMPY-03670

Species: Cynomolgus,Rhesus

Expression System: HEK293

CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPY-05354

Species: Human

Expression System: HEK293

4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)

TMPY-00033

Species: Human

Expression System: HEK293

PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated

TMPY-05815

Species: Canine

Expression System: HEK293

PD-1 Protein, Human, Recombinant (His)

TMPY-00897

Species: Human

Expression System: HEK293

PD-1 Protein, Canine, Recombinant (His)

TMPY-04342

Species: Canine

Expression System: HEK293

PD-1 Protein, Cynomolgus, Recombinant (His)

TMPY-05260

Species: Cynomolgus

Expression System: HEK293

CTLA-4 Protein, Mouse, Recombinant (His)

TMPY-01604

Species: Mouse

Expression System: HEK293

CD86 Protein, Human, Recombinant (His)

TMPY-01180

Species: Human

Expression System: HEK293

CEACAM1 Protein, Human, Recombinant (His & hFc)

TMPY-04123

Species: Human

Expression System: HEK293

CTLA-4 Protein, Human, Recombinant

TMPY-04824

Species: Human

Expression System: HEK293

CD155/PVR Protein, Rhesus, Recombinant (His)

TMPY-01612

Species: Rhesus

Expression System: HEK293

CD155/PVR Protein, Human, Recombinant (His)

TMPY-01386

Species: Human

Expression System: HEK293

OX40/TNFRSF4 Protein, Human, Recombinant (His)

TMPY-01423

Species: Human

Expression System: HEK293

B7-1 Protein, Human, Recombinant

TMPY-00674

Species: Human

Expression System: HEK293

PD-L2 Protein, Human, Recombinant (His), Biotinylated

TMPY-04957

Species: Human

Expression System: HEK293

CD28 Protein, Human, Recombinant (hFc)

TMPY-01941

Species: Human

Expression System: HEK293

ICOS ligand Protein, Human, Recombinant (His)

TMPY-01672

Species: Human

Expression System: HEK293

CD27/TNFRSF7 Protein, Human, Recombinant (His), Biotinylated

TMPY-04951

Species: Human

Expression System: Baculovirus-Insect Cells

B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-05641

Species: Human

Expression System: HEK293

CD27/TNFRSF7 Protein, Human, Recombinant (His)

TMPY-03401

Species: Human

Expression System: Baculovirus-Insect Cells

SIRP alpha Protein, Mouse, Recombinant (His)

TMPY-02632

Species: Mouse

Expression System: HEK293

PD-L2 Protein, Human, Recombinant (mFc)

TMPY-05827

Species: Human

Expression System: HEK293

CD40 Ligand Protein, Human, Recombinant (hFc)

TMPY-02022

Species: Human

Expression System: HEK293

B7-H4 Protein, Mouse, Recombinant (His)

TMPY-05322

Species: Mouse

Expression System: HEK293

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カタログ番号	製品名
L2170	Immuno-Oncology Compound Library		449 compounds
	A unique collection of 449 compounds acting on immune-oncology therapeutic targets can be used for high throughput and high content screening；

ライブラリー

Immuno-Oncology Compound Library

L2170

Compounds: 449