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天然化合物

124

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カタログ番号	製品名	別名	ターゲット
T16695	Pyrintegrin		Integrin
	Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...		Integrin
T11996	MELK-8a hydrochloride		MELK
			MELK
T38155	N-Acetyl-D-cysteine		Reactive Oxygen Species
	N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group.		Reactive Oxygen Species
T27246	EG1		Others
	EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.		Others
T8987	Epiblastin A		Casein Kinase
	Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs).		Casein Kinase
T2161	Cardiogenol C		Wnt/beta-catenin
	Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.		Wnt/beta-catenin
T24706	RBC10	RBC 10,RBC-10	GTPase
	RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines.		GTPase
T21981	Phthalazinone pyrazole		Aurora Kinase
	Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.		Aurora Kinase
T9681	MAK-683 hydrochloride		Histone Methyltransferase
	MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED). MAK683 exhibits IC50s of 59, 26, 89 nM in EED Alphascreen binding, ELISA and LC-MS assay.		Histone Methyltransferase
T6848	GSK1016790A	GSK101	Calcium Channel , TRP/TRPV Channel
	GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial cells.		Calcium Channel , TRP/TRPV Channel
T1874	PPQ-102	PPQ102,CFTR Inhibitor,PPQ 102	CFTR , Autophagy
	PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).		CFTR , Autophagy
T1759	OTSSP167	MELK inhibitor,OTS167	MELK
	OTSSP167 (OTS167) is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.		MELK
T2431	ID-8	ID8	DYRK
	ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.		DYRK
T21559	OTSSP167 hydrochloride		MELK
	OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).		MELK
T11997	MELK-IN-1	Nintedanib Impurity L,MELK inhibitor 17	MELK
	MELK-IN-1 (MELK inhibitor 17) is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM).		MELK
T3221	Oct3/4-inducer-1	2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile	Others , OCT
	Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3/4 inducer that promotes the expression and stabilization of OCT3/4 and enhances its transcriptional activity in a variety of human cells.		Others , OCT
T11571	HLY78	4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine	Wnt/beta-catenin
	HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt/β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling.		Wnt/beta-catenin
T8005	Cardiogenol C hydrochloride	Cardiogenol C HCl,Cardiogenol C	Wnt/beta-catenin
	Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).		Wnt/beta-catenin
T7196	HG-10-102-01		LRRK2
	HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).		LRRK2
TP1286	Carcinoembryonic Antigen CEA		Others
	Carcinoembryonic antigen (CEA) is a protein that is present in certain tissues of a developing baby (fetus)		Others
T3162	IDE1		Others
	IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50: 125.5 nM...		Others
T3458	EED226		Histone Methyltransferase
	EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.		Histone Methyltransferase
T15201	MAK683		Histone Methyltransferase
	MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).		Histone Methyltransferase
T24152	HTH-01-091	HTH-01091,HTH01-091,HTH 01-091,HTH 01091	Serine/threonin kinase , Pim , MELK , DYRK , CDK , RIP kinase
	HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK and CLK2. HTH-01-091 can be used to study breast cancer.
T22322	EEDi-5285	UM-EEDi-5285,EEDI5285	Histone Methyltransferase
	EEDi-5285, an orally active and highly potent inhibitor targeting embryonic ectoderm development (EED) protein, exhibits anti-cancer activity. It demonstrates exceptional efficacy with an IC50 value of 0.2 nM, indicating...		Histone Methyltransferase
T6948	Pluripotin	SC1	ERK , Raf , S6 Kinase
	Pluripotin (SC1) (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP.		ERK , Raf , S6 Kinase
T2019	OAC2		OCT
	OAC2 is an Oct4 activator which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibrobl...		OCT
T11469	GSK-3484862		DNA Methyltransferase
	GSK-3484862 is a non-covalent Dnmt1 inhibitor. It induces DNA hypomethylation to against cancer.		DNA Methyltransferase
T35834L	(Sar¹)-Angiotensin II acetate		RAAS
	(Sar¹)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. It binds to brain membrane-rich particles, with a Kd of 2.7 nM. It can stimulate protein synthesis and cell...		RAAS
T78170	Kras4B G12D-IN-1		Ras
	Kras4B G12D-IN-1 is an anticancer agent that functions as an inhibitor of the Kras4B G12D protein. It effectively reduces the expression of Kras protein in mouse embryonic fibroblasts (MEFs) harboring the Kras4B G12D mut...		Ras
T2301	SB 202190	FHPI,SB202190	Apoptosis , p38 MAPK , Autophagy
	SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably. SB 202190 has antitumor activity and also induces the differentiation of human embryonic stem cells i...		Apoptosis , p38 MAPK , Autophagy
T3637	Pifithrin-β hydrobromide	Cyclic PFT-α,PFT-β,Cyclic Pifithrin-α hydrobromide,Pifithrin-β,PFT β (hydrobromide)	Ferroptosis , p53
	Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorder...		Ferroptosis , p53
TP1345	Kisspeptin-10, human (TFA)(374675-21-5,FREE)		GPR , Kisspeptin
	Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role i...		GPR , Kisspeptin
T60143	MitoBloCK-6		Apoptosis
	MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC 50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 with IC 50 of 1.4 μM. MitoBloCK-6 can induce apoptosis via cytochrome c release in human embryo...		Apoptosis
T2310	CHIR-99021	Laduviglusib,CT99021,CHIR-99021	GSK-3 , Wnt/beta-catenin , Autophagy
	CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in...		GSK-3 , Wnt/beta-catenin , Autophagy
T28866	Stemazole		Apoptosis
	Stemazole is a novel small molecule human stem/progenitor cell proliferation activator that promotes the survival of human embryonic stem cells and maintains stemness, and promotes the survival of oligodendrocyte precurs...		Apoptosis
T36935	PKUMDL-LC-101-D04	GPX4-Activator-1d4,PKUMDL-LC-101-D04	GPX
	PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of iron death. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 μM in a cell-free...		GPX
T77697	BML-278	BML278,BML 278	Sirtuin , Histone Methyltransferase
	BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, and can be used to improve early embryonic development.BML-278 ind...		Sirtuin , Histone Methyltransferase
T2310L	CHIR-99021 HCl	CT99021 HCl,Laduviglusib HCl	GSK-3
	CHIR-99021 HCl (Laduviglusib HCl) is a highly potent and selective inhibitor of GSK-3α/β, with IC50 values of 10 nM and 6.7 nM respectively. It demonstrates remarkable selectivity for GSK-3, with over 500-fold selectivit...		GSK-3
T24129	HBX28258	HBX 28258,HBX-28258
	HBX28258 is a recombinant human USP7 protein inhibitor. In human colon cancer and embryonic kidney cell, it acts by binding the active site through a covalent mechanism and selectively inactivating USP7 protein.
T70578	BX-795 hydrochloride
	BX-795 hydrochloride is a TBK1 and IKKε inhibitor. BX-795 is a potential maternal embryonic leucine zipper kinase inhibitor.
T35549	Elsinochrome A
	Elsinochrome A is a perylenequinone fungal metabolite that has been found inHypomycesand has anticancer activity.1Photoactivation of elsinochrome A induces the production of singlet oxygen and apoptosis in R366.4 rhesus ...
T70520	TWS-119
	TWS-119 is an inhibitor of glycogen synthase kinase-3β (GSK-3β) that induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESCs).
T73867	HTH-01-091 TFA
	HTH-01-091 TFA, a potent and selective inhibitor of maternal embryonic leucine zipper kinase (MELK), exhibits an IC50 of 10.5 nM. Besides its primary target, it also inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK, and CLK2, pos...
T73945	MAK683-CH2CH2COOH hydrochloride
	MAK683-CH2CH2COOH, targeting embryonic ectoderm development protein (EED), alongside a VHL ligand for E3 ubiquitin ligase, contributes to the formulation of PROTAC EED degrader-1 and PROTAC EED degrader-2 [1].
T40154	FTX-6058
	FTX-6058 is a potent orally active inhibitor targeting Embryonic Ectoderm Development (EED). It effectively induces HbF protein expression in both cell and murine models. This compound holds significant potential for res...
T69429	Y27632 HCl hydrate
	Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriuretic peptide production, cell size, protein synthesis, and myofibrillar organization. Y27632 prevents dimethylnitrosamine-induced hepa...
T40155	FTX-6058 hydrochloride
	FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED), with the ability to induce HbF protein expression in both cell and murine models. This compound is particularly valu...
T69743	MEDS433
	MEDS433 is a dihydroorotate dehydrogenase inhibitor (IC50 1.2 nM). MEDS433 inhibited the in vitro replication of hCoV-OC43 and hCoV-229E, as well as of SARS-CoV-2, at low nanomolar range. Notably, the anti-SARS-CoV-2 act...
T35561	MS351
	MS351 is an antagonist of chromobox 7 (CBX7) that acts by binding the CBX7 chromodomain. It enhances the binding of long noncoding RNA to the CBX7 chromodomain when used at 25 μM. MS351 induces transcriptional derepressi...

Compounds

MELK-8a hydrochloride

Target: Reactive Oxygen Species

Target: Casein Kinase

Cardiogenol C

T2161

Synonym:

Target: Wnt/beta-catenin

RBC10

T24706

Synonym: RBC 10,RBC-10

Target: GTPase

Phthalazinone pyrazole

T21981

Synonym:

Target: Aurora Kinase

MAK-683 hydrochloride

T9681

Synonym:

Target: Histone Methyltransferase

GSK1016790A

T6848

Synonym: GSK101

Target: Calcium Channel, TRP/TRPV Channel

PPQ-102

T1874

Synonym: PPQ102,CFTR Inhibitor,PPQ 102

Target: CFTR, Autophagy

OTSSP167

T1759

Synonym: MELK inhibitor,OTS167

OTSSP167 hydrochloride

Synonym: Nintedanib Impurity L,MELK inhibitor 17

Target: MELK

Oct3/4-inducer-1

T3221

Synonym: 2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile

Target: Others, OCT

HLY78

T11571

Synonym: 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine

Target: Wnt/beta-catenin

Cardiogenol C hydrochloride

T8005

Synonym: Cardiogenol C HCl,Cardiogenol C

Target: Wnt/beta-catenin

Carcinoembryonic Antigen CEA

Target: Histone Methyltransferase

MAK683

T15201

Synonym:

Target: Histone Methyltransferase

HTH-01-091

T24152

Synonym: HTH-01091,HTH01-091,HTH 01-091,HTH 01091

Target: Serine/threonin kinase, Pim, MELK, DYRK, CDK, RIP kinase

EEDi-5285

T22322

Synonym: UM-EEDi-5285,EEDI5285

Target: Histone Methyltransferase

Pluripotin

T6948

Synonym: SC1

Target: ERK, Raf, S6 Kinase

Target: DNA Methyltransferase

(Sar¹)-Angiotensin II acetate

Synonym: FHPI,SB202190

Target: Apoptosis, p38 MAPK, Autophagy

Pifithrin-β hydrobromide

T3637

Synonym: Cyclic PFT-α,PFT-β,Cyclic Pifithrin-α hydrobromide,Pifithrin-β,PFT β (hydrobromide)

Target: Ferroptosis, p53

Kisspeptin-10, human (TFA)(374675-21-5,FREE)

TP1345

Synonym:

Target: GPR, Kisspeptin

Synonym: Laduviglusib,CT99021,CHIR-99021

Target: GSK-3, Wnt/beta-catenin, Autophagy

Synonym: GPX4-Activator-1d4,PKUMDL-LC-101-D04

Target: GPX

BML-278

T77697

Synonym: BML278,BML 278

Target: Sirtuin, Histone Methyltransferase

CHIR-99021 HCl

T2310L

Synonym: CT99021 HCl,Laduviglusib HCl

Target: GSK-3

HBX28258

T24129

Synonym: HBX 28258,HBX-28258

MAK683-CH2CH2COOH hydrochloride

FTX-6058 hydrochloride

カタログ番号	製品名	別名	ターゲット
T19720	Colcemid	C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine	Microtubule Associated
	Colcemid (NSC-3096) is an inhibitor of microtubule polymerization. It used to study embryonic cloning.		Microtubule Associated
T4S1102	Liensinine diperchlorate	Liensinine-Perchlorate	Mitophagy , Others , Autophagy
	Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus. It inhibits late autophagy by blocking autophagosome-lysosome fusion and exhibits biological activities such as...		Mitophagy , Others , Autophagy
T75661	Thymopentin acetate
	Thymopentin acetate, primarily secreted by the epithelial cells of the thymic cortex and medulla, serves as an effective immunomodulatory agent. It possesses a short plasma half-life of 30 seconds and significantly enhan...
T36954	Nemorosone
	Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma ce...

天然物製品

Colcemid

T19720

Synonym: C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine

Target: Microtubule Associated

Liensinine diperchlorate

T4S1102

Synonym: Liensinine-Perchlorate

Target: Mitophagy, Others, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02379	EED Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	EED is essential for regulating the repressive histone modification, histone 3 lysine 27 tri-methylation (H3K27me3) at many developmental genes. EED depletion significantly impeded erythroid maturation. EED depletion imp...
TMPY-04126	MUSTN1 Protein, Human, Recombinant (His)	Human	E. coli
	MUSTN1 (Musculoskeletal, Embryonic Nuclear Protein 1) is a Protein Coding gene. It may play an important role in regulating musculoskeletal development in mammals. It belongs to the MUSTANG family. The MUSTN1 protein is ...
TMPY-03104	FGF-17 Protein, Human, Recombinant	Human	E. coli
	FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including ...
TMPJ-00090	FGF-9 Protein, Human, Recombinant	Human	E. coli
	Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inc...
TMPJ-00258	TGF beta 2 Protein, Human, Recombinant	Human	HEK293 Cells
	Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T...
TMPY-01061	FGF-10 Protein, Human, Recombinant	Human	E. coli
	Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPY-03382	FGF-6 Protein, Human, Recombinant	Human	E. coli
	FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, includi...
TMPJ-00562	PDGF-BB Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P...
TMPJ-00842	FGF-2 Protein, Rat, Recombinant	Rat	E. coli
	FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. ...
TMPJ-01471	Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant	Human/Mouse/Rat	HEK293 Cells
	Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purifi...
TMPY-02907	FGF-19 Protein, Human, Recombinant	Human	E. coli
	FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inclu...
TMPJ-00037	FGF-2 Protein, Mouse, Recombinant	Mouse	E. coli
	FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mo...
TMPY-05004	FGF-4 Protein, Human, Recombinant	Human	E. coli
	FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati...
TMPJ-01065	Noggin/NOG Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept...
TMPJ-01011	FGF-9 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine a...
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPH-01895	POU5F1 Protein, Human, Recombinant (B2M & His)	Human	E. coli
	Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, F...
TMPH-02858	Wnt2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Functions as upstream regulator of FGF10 expression. Plays an important role in e...
TMPH-01602	LAMA5 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix co...
TMPJ-00096	FGF-17 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Fibroblast Growth Factor 17 (FGF17) is a member of the heparin-binding growth factors family that is prominently expressed in the cerebellum and cortex. Proteins of this family possess broad mitogenic and cell survival a...
TMPH-03321	KRTDAP Protein, Rat, Recombinant (His & SUMO)	Rat	E. coli
	May act as a soluble regulator of keratinocyte differentiation. May play an important role in embryonic skin morphogenesis. KRTDAP Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6...
TMPJ-00677	TGOLN2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	This protein may be involved in regulating membrane traffic to and from trans-Golgi network. Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed i...
TMPH-00068	Vitellogenin Protein, Apis mellifera, Recombinant (His)	Apis mellifera	E. coli
	Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development. Involved in the differentiation of honeybee larvae into queens. Vitellogenin Protein, Apis mellifera, Recombinant (His) is ex...
TMPH-01355	FXR1 Protein, Human, Recombinant (His)	Human	E. coli
	RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs. FXR1 Protein, Human, Recombinant (His) is expressed in E...
TMPK-01186	B7-H5/Gi24/VISTA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	B7-H5, also known as VISTA , B7H5, Dies1, SISP1 and C10orf54, is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. B7-...
TMPJ-00835	FGF-4 Protein, Mouse, Recombinant	Mouse	E. coli
	Fibroblast growth factor 4(FGF-4) is a heparin binding member of the FGF family. The human FGF4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that ...
TMPH-02293	UGDH Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role i...
TMPH-02865	Wnt3 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal ...
TMPK-00868	Notch 4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The Notch signaling pathway is important for cell-cell communication; it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression ...
TMPY-04828	TFF3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Trefoil factor family (TFF) peptides are involved in the maintenance of epithelial integrity and epithelial restitution. Trefoil factor-3 (TFF3) is an estrogen-regulated gene associated with prognosis in different types ...
TMPK-00520	PTK7/CCK4 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system...
TMPK-00232	CEACAM6 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) belongs to the human carcino-embryonic antigen (CEA) family. Numerous lines of studies have indicated that altered expression of CEACAM6 may have a role...
TMPK-01311	CEACAM6 Protein, Cynomolgus, Recombinant (aa 35-320, His)	Cynomolgus	HEK293 Cells
	Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) belongs to the human carcino-embryonic antigen (CEA) family. Numerous lines of studies have indicated that altered expression of CEACAM6 may have a role...
TMPH-02013	PTPRZ1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligo...
TMPJ-01300	PDCD10 Protein, Human, Recombinant	Human	E. coli
	Programmed Cell Death Protein 10 (PDCD10) belongs to the PDCD10 family. PDCD10 exists as a homodimer and is widely expressed. PDCD10 can increase mitogen-activated protein kinase activity and MST4 activity. PDCD10 is req...
TMPJ-00879	HOXB4 Protein, Human,Recombinant (L175D, E176K, E178K, His)	Human	E. coli
	Homeobox B4 (HOXB4) is encoded by the HOXB4 gene which is a member of the the class I homeobox (HOX) gene family and encodes a nuclear protein with a homeobox DNA-binding domain. These genes are master control regulators...
TMPK-00233	CEACAM6 Protein, Human, Recombinant (aa 35-320, His & Avi), Biotinylated	Human	HEK293 Cells
	Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) belongs to the human carcino-embryonic antigen (CEA) family. Numerous lines of studies have indicated that altered expression of CEACAM6 may have a role...
TMPK-01185	B7-H5/Gi24/VISTA Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	B7-H5, also known as VISTA , B7H5, Dies1, SISP1 and C10orf54, is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. B7-...
TMPJ-00517	WIF-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Wnt Inhibitory Factor 1 (WIF1) is a secreted protein, which binds WNT proteins and inhibits their activities. WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 cont...
TMPK-01280	HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
	Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and ...
TMPK-00359	Endoglin/CD105 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis...
TMPK-00061	IGF2/IGF-II Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins. All three ligands are involved in c...
TMPJ-01016	INHBC Protein, Human, Recombinant (N-His)	Human	E. coli
	Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation,...
TMPJ-00692	GAS7 Protein, Human, Recombinant (His)	Human	E. coli
	Growth Arrest-Specific Protein 7 (GAS7) is expressed primarily in terminalaly differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 may play a role in neuronal development by promoting ...
TMPY-04133	UNC5B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPK-00453	HER3/ERBB3 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and ...
TMPH-01530	INHBA Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary...
TMPH-02864	Wnt1 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is ...
TMPK-00452	HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled	Human	HEK293 Cells
	Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and ...
TMPK-01080	PTK7/CCK4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system...
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EED Protein, Human, Recombinant (His & GST)

TMPY-02379

Species: Human

Expression System: Baculovirus Insect Cells

MUSTN1 Protein, Human, Recombinant (His)

TMPY-04126

Species: Human

Expression System: E. coli

FGF-17 Protein, Human, Recombinant

TMPY-03104

Species: Human

Expression System: E. coli

FGF-9 Protein, Human, Recombinant

TMPJ-00090

Species: Human

Expression System: E. coli

TGF beta 2 Protein, Human, Recombinant

TMPJ-00258

Species: Human

Expression System: HEK293 Cells

FGF-10 Protein, Human, Recombinant

TMPY-01061

Species: Human

Expression System: E. coli

FGF-6 Protein, Human, Recombinant

TMPY-03382

Species: Human

Expression System: E. coli

PDGF-BB Protein, Mouse, Recombinant (His)

TMPJ-00562

Species: Mouse

Expression System: E. coli

FGF-2 Protein, Rat, Recombinant

TMPJ-00842

Species: Rat

Expression System: E. coli

Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant

TMPJ-01471

Species: Human/Mouse/Rat

Expression System: HEK293 Cells

FGF-19 Protein, Human, Recombinant

TMPY-02907

Species: Human

Expression System: E. coli

FGF-2 Protein, Mouse, Recombinant

TMPJ-00037

Species: Mouse

Expression System: E. coli

FGF-4 Protein, Human, Recombinant

TMPY-05004

Species: Human

Expression System: E. coli

Noggin/NOG Protein, Mouse, Recombinant (His)

TMPJ-01065

Species: Mouse

Expression System: HEK293 Cells

FGF-9 Protein, Mouse, Recombinant (His)

TMPJ-01011

Species: Mouse

Expression System: E. coli

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

TMPJ-00412

Species: Human

Expression System: HEK293 Cells

POU5F1 Protein, Human, Recombinant (B2M & His)

TMPH-01895

Species: Human

Expression System: E. coli

Wnt2 Protein, Mouse, Recombinant (His)

TMPH-02858

Species: Mouse

Expression System: E. coli

LAMA5 Protein, Human, Recombinant (His & SUMO)

TMPH-01602

Species: Human

Expression System: E. coli

FGF-17 Protein, Human, Recombinant (His)

TMPJ-00096

Species: Human

Expression System: HEK293 Cells

KRTDAP Protein, Rat, Recombinant (His & SUMO)

TMPH-03321

Species: Rat

Expression System: E. coli

TGOLN2 Protein, Human, Recombinant (His)

TMPJ-00677

Species: Human

Expression System: HEK293 Cells

Vitellogenin Protein, Apis mellifera, Recombinant (His)

TMPH-00068

Species: Apis mellifera

Expression System: E. coli

FXR1 Protein, Human, Recombinant (His)

TMPH-01355

Species: Human

Expression System: E. coli

B7-H5/Gi24/VISTA Protein, Human, Recombinant (His)

TMPK-01186

Species: Human

Expression System: HEK293 Cells

FGF-4 Protein, Mouse, Recombinant

TMPJ-00835

Species: Mouse

Expression System: E. coli

UGDH Protein, Human, Recombinant (His & SUMO)

TMPH-02293

Species: Human

Expression System: E. coli

Wnt3 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02865

Species: Mouse

Expression System: E. coli

Notch 4 Protein, Mouse, Recombinant (His)

TMPK-00868

Species: Mouse

Expression System: HEK293 Cells

TFF3 Protein, Human, Recombinant (His)

TMPY-04828

Species: Human

Expression System: HEK293 Cells

PTK7/CCK4 Protein, Cynomolgus, Recombinant (His)

TMPK-00520

Species: Cynomolgus

Expression System: HEK293 Cells

CEACAM6 Protein, Human, Recombinant (His & Avi)

TMPK-00232

Species: Human

Expression System: HEK293 Cells

CEACAM6 Protein, Cynomolgus, Recombinant (aa 35-320, His)

TMPK-01311

Species: Cynomolgus

Expression System: HEK293 Cells

PTPRZ1 Protein, Human, Recombinant (His)

TMPH-02013

Species: Human

Expression System: P. pastoris (Yeast)

PDCD10 Protein, Human, Recombinant

TMPJ-01300

Species: Human

Expression System: E. coli

HOXB4 Protein, Human,Recombinant (L175D, E176K, E178K, His)

TMPJ-00879

Species: Human

Expression System: E. coli

CEACAM6 Protein, Human, Recombinant (aa 35-320, His & Avi), Biotinylated

TMPK-00233

Species: Human

Expression System: HEK293 Cells

B7-H5/Gi24/VISTA Protein, Human, Recombinant (hFc)

TMPK-01185

Species: Human

Expression System: HEK293 Cells

WIF-1 Protein, Human, Recombinant (His)

TMPJ-00517

Species: Human

Expression System: HEK293 Cells

HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

TMPK-01280

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

Endoglin/CD105 Protein, Human, Recombinant (His & Avi)

TMPK-00359

Species: Human

Expression System: HEK293 Cells

IGF2/IGF-II Protein, Human, Recombinant (hFc)

TMPK-00061

Species: Human

Expression System: HEK293 Cells

INHBC Protein, Human, Recombinant (N-His)

TMPJ-01016

Species: Human

Expression System: E. coli

GAS7 Protein, Human, Recombinant (His)

TMPJ-00692

Species: Human

Expression System: E. coli

UNC5B Protein, Human, Recombinant (His)

TMPY-04133

Species: Human

Expression System: HEK293 Cells

HER3/ERBB3 Protein, Human, Recombinant (His & Avi)

TMPK-00453

Species: Human

Expression System: HEK293 Cells

INHBA Protein, Human, Recombinant (His & SUMO)

TMPH-01530

Species: Human

Expression System: E. coli

Wnt1 Protein, Mouse, Recombinant (His & Myc)

TMPH-02864

Species: Mouse

Expression System: E. coli

HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled

TMPK-00452

Species: Human

Expression System: HEK293 Cells

PTK7/CCK4 Protein, Mouse, Recombinant (His)

TMPK-01080

Species: Mouse

Expression System: HEK293 Cells

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カタログ番号	製品名
L4300	Wnt/Hedgehog/Notch Compound Library	237 compounds
	A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
L1380	Transcription Factor-Targeted Compound Library	695 compounds
	Well-chosen 695 compounds with unique structures targeting transcription factor;
L4100	TGF-beta/Smad Compound Library	184 compounds
	A unique collection of 184 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;
L8000	Stem Cell Differentiation Compound Library	1197 compounds
	A unique collection of 1197 stem cell differentiation signaling targeted compounds for high throughput and high content screening;

ライブラリー

Wnt/Hedgehog/Notch Compound Library

L4300

Compounds: 237

Transcription Factor-Targeted Compound Library

L1380

Compounds: 695

TGF-beta/Smad Compound Library

L4100

Compounds: 184

Stem Cell Differentiation Compound Library

L8000

Compounds: 1197