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Search Results for " glucocorticoid "

ターゲット

Glucocorticoid Receptor Glucocorticoid Receptor

154

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T37908	Glucocorticoid receptor agonist-1		Glucocorticoid Receptor
	Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM[1].		Glucocorticoid Receptor
T67742	EX-A5386	Glucocorticoid receptor modulator-1	Glucocorticoid Receptor
	EX-A5386 (Glucocorticoid receptor modulator-1) is a potent glucocorticoid receptor modulator, IC50/EC50<100nM.		Glucocorticoid Receptor
T11417	Glucocorticoid receptor agonist		Others
	Glucocorticoid receptor agonist is an effective glucocorticoid receptor agonist.		Others
T72102	Glucocorticoid receptor modulator 1
	Glucocorticoid receptor modulator 1 is a potent, orally active, non-steroidal selective glucocorticoid receptor modulator, exhibiting IC50 values of 9 nM and 130 nM against NF-κB and AP-1, respectively. It effectively re...
T74697	Glucocorticoid receptor agonist-2
	Glucocorticoid receptor agonist-2 (compound 21), a glucocorticoid receptor agonist exhibiting an IC50 value of 6.6 nM, serves as an active reference for ABBV-3373 [1]. This compound is instrumental in the synthesis of an...
T63551	Glucocorticoid receptor-IN-1
	Glucocorticoid receptor-IN-1 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. glucocorticoid receptor-IN-1 has good transcriptional repression, acting on hMMP1 ( IC50:...
T63539	Glucocorticoid receptor-IN-2
	Glucocorticoid receptor-IN-2 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. IC50: 0.171 nM) and also has some transcriptional activating effect on MMTV (EC50: 0.94 n...
T75016	Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal
	Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Mal functions as a glucocorticoid receptor agonist, utilized in the formulation of anti-CD40 antibody agent conjugates (ADC). It serves as a research tool for exploring...
T77835	Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br
	Glucocorticoid Receptor Agonist-1 Phosphate (Gly-Glu-Br) is an antibody-drug conjugate (ADC) linker utilized in the synthesis of ABBV-154, ABBV-927, ABBV-368, and related analogs [1].
T74116	Glucocorticoid receptor agonist-1 Ala-Ala-Mal
	Glucocorticoid receptor agonist-1 Ala-Ala-Mal (compound 88), a glucocorticosteroid and glucocorticoid receptor agonist, can be conjugated with Adalimumab to formulate an ADC [1].
T77869	Glucocorticoid receptor agonist-2 Ala-Ala-Mal
	Glucocorticoid receptor agonist-2 Ala-Ala-Mal (compound 79) serves as a precursor for synthesizing anti-inflammatory antibody-drug conjugate (ADC) molecules and acts as an active reference for ABBV-3373 [1].
T6635	EMD638683		SGK
	EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 μM).		SGK
T82303	Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA
	Glucocorticoid Receptor Agonist-1 Phosphate Gly-Glu (TFA) serves as a cleavable linker for the synthesis of Antibody-Drug Conjugates (ADCs).
T75130	Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br
	Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Br is a drug-linker conjugate for antibody-drug conjugates (ADCs), serving as a reaction reagent in the creation of anti-CD40 antibody agent conjugates [1].
T9977	SGK1-IN-4		SGK
	SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.		SGK
T2622	GSK 650394	GSK650394	SGK , Influenza Virus
	GSK 650394 is a serum- and glucocorticoid-regulated kinase-1 inhibitor.		SGK , Influenza Virus
T15451	GW-870086		Glucocorticoid Receptor
	GW-870086 is an effective anti-inflammatory agent. GW-870086 also plays a role in a glucocorticoid receptor agonist (pIC50: 10.1 in A549 cells expressing NF-κB).		Glucocorticoid Receptor
T14377	AZD5423		Glucocorticoid Receptor
	AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.		Glucocorticoid Receptor
T8777	Beclometasone	BecloMethasone	Glucocorticoid Receptor
	Beclometasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma.		Glucocorticoid Receptor
T14981	Clobetasone butyrate		Glucocorticoid Receptor
	Clobetasone butyrate, a synthetic glucocorticoid with topical anti-inflammatory activity, is effective in treating corticosteroid-responsive dermatoses, such as atopic dermatitis and psoriasis, especially within skin tis...		Glucocorticoid Receptor
T17217	Vamorolone	VBP15	Glucocorticoid Receptor , NF-κB
	Vamorolone (VBP15) is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects. Vamorolone displays effective NF-κB inhibition an...		Glucocorticoid Receptor , NF-κB
T1163	Betamethasone valerate	Betnovate,Betaderm,Betamethasone 17-valerate,Luxiq	Glucocorticoid Receptor
	Betamethasone valerate (Luxiq) is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions.		Glucocorticoid Receptor
T0820	Triamcinolone acetonide	Aristogel,Azmacort,Aristoderm	Glucocorticoid Receptor
	Triamcinolone acetonide (Azmacort) is a Corticosteroid. The mechanism of action of triamcinolone acetonide is as a Corticosteroid Hormone Receptor Agonist. It is an anti-inflammatory glucocorticoid used topically in the ...		Glucocorticoid Receptor
T6502	Fluocinonide	Lidex,Metosyn,Topsyn	Glucocorticoid Receptor
	Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent.		Glucocorticoid Receptor
T8396	Prednisone acetate	Prednisone 21-acetate	Glucocorticoid Receptor
	Prednisone acetate (Prednisone 21-acetate) is a glucocorticoid receptor agonist with immunomodulating properties and anti-inflammatory.		Glucocorticoid Receptor
T0261	Amcinonide	CL-34699	Glucocorticoid Receptor , Annexin A
	Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.		Glucocorticoid Receptor , Annexin A
T0367	Fluocinolone (Acetonide)	Fluocinolone acetonide,Flucort-N	Glucocorticoid Receptor
	Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in...		Glucocorticoid Receptor
T3316	Fluorometholone	Fluoromethalone,Cortilet,Oxylone,Delmeson	Glucocorticoid Receptor
	Fluorometholone (Fluoromethalone) is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon). Fluorometholone acetate ophthalmic susp...		Glucocorticoid Receptor
T0181	Loteprednol etabonate	Lotemax,Alrex	Glucocorticoid Receptor , Antibacterial , Antibiotic
	Loteprednol etabonate (Lotemax) is an ophthalmic analog of the corticosteroid prednisolone with anti-inflammatory activity.		Glucocorticoid Receptor , Antibacterial , Antibiotic
T1076	Dexamethasone	MK 125,Prednisolone F,NSC 34521,Hexadecadrol	Glucocorticoid Receptor , Mitophagy , IL Receptor , SARS-CoV , Antibacterial , Antibiotic , Autophagy , Complement System
	Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and an IL receptor modulator. Dexamethasone has anti-inflammatory and immunosuppressive activity and induces autophagy. Dexamethasone inhibits LPS-induced...
T6713	Ulipristal		Estrogen/progestogen Receptor , Progesterone Receptor
	Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.		Estrogen/progestogen Receptor , Progesterone Receptor
T1749	AL 082D06	D-06,AL082D06	Glucocorticoid Receptor
	AL 082D06 (D-06), a selective nonsteroidal glucocorticoid receptor (GR) antagonist (Ki: 210 nM), exhibits outstanding selectivity against AR, ER, MR and PR(Ki > 10 uM).		Glucocorticoid Receptor
TQ0225	Velsecorat	AZD7594,AZ13189620	Glucocorticoid Receptor
	Velsecorat (AZD7594) is an effective and selective nonsteroidal glucocorticoid receptor modulator (IC50: 0.9 nM).		Glucocorticoid Receptor
T2526	Ciclesonide	Zetonna,RPR251526,Omnaris,Alvesco	Glucocorticoid Receptor
	Ciclesonide (Alvesco)(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases.		Glucocorticoid Receptor
T0094	Budesonide	Entocort,Pulmicort,Rhinocort	Glucocorticoid Receptor
	Budesonide (Pulmicort), an anti-inflammatory corticosteroid, has shown the effective glucocorticoid activitie and few mineralocorticoid activities. According to reports, Budesonide has extensively inhibitory effects agai...		Glucocorticoid Receptor
T22367	Methylprednisolone succinate	Methylprednisolone hemisuccinate,Methylprednisolone hydrogen succinate	Glucocorticoid Receptor
	Methylprednisolone succinate (Methylprednisolone hemisuccinate) is a synthetic glucocorticoid and is widely used as an anti-inflammatory agent.		Glucocorticoid Receptor
T1531	Mometasone furoate	Sch32088	Glucocorticoid Receptor
	Mometasone furoate (Sch32088) is a pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for ski...		Glucocorticoid Receptor
T6580	Meprednisone	SCH 4358,Methylprednisone,NSC 527579,Betanisona,Betapar	Glucocorticoid Receptor , Autophagy
	Betapar(Meprednisone (Betapar)) is a glucocorticoid and a methylated derivative of prednisone.		Glucocorticoid Receptor , Autophagy
T21404	Fluticasone furoate	Veramyst,Allermist,Avamys,Fluticasone furoate	Glucocorticoid Receptor
	Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure...		Glucocorticoid Receptor
T6503	Fluorometholone Acetate	NSC 47438,Flarex,Eflone,Oxylone acetate	Glucocorticoid Receptor , Carbonic Anhydrase
	Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.		Glucocorticoid Receptor , Carbonic Anhydrase
T2527	Ulipristal acetate	Ulipristal,CDB-2914	Estrogen/progestogen Receptor , Progesterone Receptor , Autophagy
	Ulipristal acetate (CDB-2914) is an orally bioavailable, acetate salt of ulipristal, a selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereb...
T16079	Mirodenafil	SK3530	PDE
	Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.		PDE
T0947L	Dexamethasone Phosphate disodium	EGP-437,EGP437. Dex-Phos,EGP 437	Glucocorticoid Receptor
	Dexamethasone Phosphate disodium (EGP437. Dex-Phos) is a water-soluble form of the synthetic glucocorticoid dexamethasone.		Glucocorticoid Receptor
T0208	Prednisolone disodium phosphate	Prednisolone phosphate sodium,Prednisolone 21-phosphate disodium	Glucocorticoid Receptor
	Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties.		Glucocorticoid Receptor
T1127	Beclometasone dipropionate	Beclovent,Beclomethasone dipropionate,Beconase,Vancenase	Glucocorticoid Receptor
	Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone...		Glucocorticoid Receptor
T19913	CKI-7	CKI 7 2HCl,CKI-7 dihydrochloride,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl	ROCK , SGK , Casein Kinase , CDK , S6 Kinase
	CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.		ROCK , SGK , Casein Kinase , CDK , S6 Kinase
T0188	Fluticasone (propionate)	CCI-187881,Fluticasone propionate	Glucocorticoid Receptor , Virus Protease , Estrogen/progestogen Receptor , Phospholipase , Endogenous Metabolite
	Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist.
T1102	Mifepristone	C-1073,RU486,RU 38486	Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , NO Synthase , Autophagy
	Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.
T1559	Betamethasone dipropionate	Diprolene AF,SCH 11460,Betamethasone 17,21-dipropionate,Diprolene,Diprosone	Glucocorticoid Receptor
	Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate (SCH 11460) binds to sp...		Glucocorticoid Receptor
T4602	Hydrocortisone hemisuccinate	Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate	Glucocorticoid Receptor , Others , Interleukin
	Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.		Glucocorticoid Receptor , Others , Interleukin

Compounds

Glucocorticoid receptor agonist-1

T37908

Synonym:

Target: Glucocorticoid Receptor

EX-A5386

T67742

Synonym: Glucocorticoid receptor modulator-1

Target: Glucocorticoid Receptor

Glucocorticoid receptor agonist

T11417

Synonym:

Target: Others

Glucocorticoid receptor modulator 1

T72102

Synonym:

Target:

Glucocorticoid receptor agonist-2

T74697

Synonym:

Target:

Glucocorticoid receptor-IN-1

T63551

Synonym:

Target:

Glucocorticoid receptor-IN-2

T63539

Synonym:

Target:

Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal

T75016

Synonym:

Target:

Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br

T77835

Synonym:

Target:

Glucocorticoid receptor agonist-1 Ala-Ala-Mal

T74116

Synonym:

Target:

Glucocorticoid receptor agonist-2 Ala-Ala-Mal

Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA

T82303

Synonym:

Target:

Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br

Target: SGK, Influenza Virus

GW-870086

T15451

Synonym:

Target: Glucocorticoid Receptor

AZD5423

T14377

Synonym:

Target: Glucocorticoid Receptor

Beclometasone

T8777

Synonym: BecloMethasone

Target: Glucocorticoid Receptor

Clobetasone butyrate

T14981

Synonym:

Target: Glucocorticoid Receptor

Vamorolone

T17217

Synonym: VBP15

Target: Glucocorticoid Receptor, NF-κB

Betamethasone valerate

T1163

Synonym: Betnovate,Betaderm,Betamethasone 17-valerate,Luxiq

Target: Glucocorticoid Receptor

Triamcinolone acetonide

T0820

Synonym: Aristogel,Azmacort,Aristoderm

Target: Glucocorticoid Receptor

Fluocinonide

T6502

Synonym: Lidex,Metosyn,Topsyn

Target: Glucocorticoid Receptor

Prednisone acetate

T8396

Synonym: Prednisone 21-acetate

Target: Glucocorticoid Receptor

Amcinonide

T0261

Synonym: CL-34699

Target: Glucocorticoid Receptor, Annexin A

Fluocinolone (Acetonide)

T0367

Synonym: Fluocinolone acetonide,Flucort-N

Target: Glucocorticoid Receptor

Fluorometholone

T3316

Synonym: Fluoromethalone,Cortilet,Oxylone,Delmeson

Target: Glucocorticoid Receptor

Loteprednol etabonate

T0181

Synonym: Lotemax,Alrex

Target: Glucocorticoid Receptor, Antibacterial, Antibiotic

Dexamethasone

T1076

Synonym: MK 125,Prednisolone F,NSC 34521,Hexadecadrol

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, SARS-CoV, Antibacterial, Antibiotic, Autophagy, Complement System

Ulipristal

T6713

Synonym:

Target: Estrogen/progestogen Receptor, Progesterone Receptor

AL 082D06

T1749

Synonym: D-06,AL082D06

Target: Glucocorticoid Receptor

Velsecorat

TQ0225

Synonym: AZD7594,AZ13189620

Target: Glucocorticoid Receptor

Ciclesonide

T2526

Synonym: Zetonna,RPR251526,Omnaris,Alvesco

Target: Glucocorticoid Receptor

Budesonide

T0094

Synonym: Entocort,Pulmicort,Rhinocort

Target: Glucocorticoid Receptor

Methylprednisolone succinate

T22367

Synonym: Methylprednisolone hemisuccinate,Methylprednisolone hydrogen succinate

Target: Glucocorticoid Receptor

Mometasone furoate

T1531

Synonym: Sch32088

Target: Glucocorticoid Receptor

Meprednisone

T6580

Synonym: SCH 4358,Methylprednisone,NSC 527579,Betanisona,Betapar

Target: Glucocorticoid Receptor, Autophagy

Fluticasone furoate

T21404

Synonym: Veramyst,Allermist,Avamys,Fluticasone furoate

Target: Glucocorticoid Receptor

Fluorometholone Acetate

T6503

Synonym: NSC 47438,Flarex,Eflone,Oxylone acetate

Target: Glucocorticoid Receptor, Carbonic Anhydrase

Ulipristal acetate

T2527

Synonym: Ulipristal,CDB-2914

Target: Estrogen/progestogen Receptor, Progesterone Receptor, Autophagy

Dexamethasone Phosphate disodium

T0947L

Synonym: EGP-437,EGP437. Dex-Phos,EGP 437

Target: Glucocorticoid Receptor

Prednisolone disodium phosphate

T0208

Synonym: Prednisolone phosphate sodium,Prednisolone 21-phosphate disodium

Target: Glucocorticoid Receptor

Beclometasone dipropionate

T1127

Synonym: Beclovent,Beclomethasone dipropionate,Beconase,Vancenase

Target: Glucocorticoid Receptor

CKI-7

T19913

Synonym: CKI 7 2HCl,CKI-7 dihydrochloride,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl

Target: ROCK, SGK, Casein Kinase, CDK, S6 Kinase

Fluticasone (propionate)

T0188

Synonym: CCI-187881,Fluticasone propionate

Target: Glucocorticoid Receptor, Virus Protease, Estrogen/progestogen Receptor, Phospholipase, Endogenous Metabolite

Mifepristone

T1102

Synonym: C-1073,RU486,RU 38486

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, NO Synthase, Autophagy

Betamethasone dipropionate

T1559

Synonym: Diprolene AF,SCH 11460,Betamethasone 17,21-dipropionate,Diprolene,Diprosone

Target: Glucocorticoid Receptor

Hydrocortisone hemisuccinate

T4602

Synonym: Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate

Target: Glucocorticoid Receptor, Others, Interleukin

カタログ番号	製品名	別名	ターゲット
T1560	Prednisolone	Predonine,Hydroretrocortine,Metacortandralone	Glucocorticoid Receptor , Endogenous Metabolite
	Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.		Glucocorticoid Receptor , Endogenous Metabolite
T1168	Desonide	Tridesilon,Locapred,Prednacinolone	Glucocorticoid Receptor
	Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated ...		Glucocorticoid Receptor
T1614	Hydrocortisone	Cortisol	Glucocorticoid Receptor , Endogenous Metabolite
	Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolytic metabolism, gluconeogenesis, capillary wall stabilizatio...		Glucocorticoid Receptor , Endogenous Metabolite
T0798	Triamcinolone	Fluoxyprednisolone,Aristocort,Rodinolone	Glucocorticoid Receptor , COX
	Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca...		Glucocorticoid Receptor , COX
T2884	Cortisone	Kendall's compound E,17-Hydroxy-11-dehydrocorticosterone	Glucocorticoid Receptor , Endogenous Metabolite
	Cortisone (17-Hydroxy-11-dehydrocorticosterone) is a corticosteroid with potent glucocorticoid activity.		Glucocorticoid Receptor , Endogenous Metabolite
T0034	Cortisone acetate	Cortisone 21-acetate,NSC 49420	Glucocorticoid Receptor , Endogenous Metabolite
	Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate (NSC-49420) d...		Glucocorticoid Receptor , Endogenous Metabolite
T1243	Hydrocortisone acetate	Cortisol 21-acetate,Hydrocortisone 21-acetate	Glucocorticoid Receptor , Annexin A , Endogenous Metabolite
	Hydrocortisone acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties.
T2810	(20S)-Protopanaxatriol	20(S)-APPT,g-PPT	Apoptosis , Estrogen Receptor/ERR , Glucocorticoid Receptor , Estrogen/progestogen Receptor , Liver X Receptor
	(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid receptor.
T2748	Cortodoxone	11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol	Glucocorticoid Receptor , Endogenous Metabolite
	Cortodoxone (11-Desoxycortisol) is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland.		Glucocorticoid Receptor , Endogenous Metabolite
T0948L	Corticosterone	17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants)	Glucocorticoid Receptor , Endogenous Metabolite
	Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stres...		Glucocorticoid Receptor , Endogenous Metabolite
T1261	Medroxyprogesterone Acetate	Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,Farlutin,Medroxyprogesterone (acetate)	Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , Androgen Receptor , Endogenous Metabolite
	Medroxyprogesterone Acetate (Farlutin) is a synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been...
T1683	Actriol	Epiestriol	Glucocorticoid Receptor
	Actriol (Epiestriol) is always used as Glucocorticoid Receptor agonist.		Glucocorticoid Receptor
T6343	Geldanamycin	NSC 122750	HSP , Influenza Virus , Tyrosine Kinases , Antibacterial , Antibiotic
	Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.
T0269	Dichlorisone Acetate	Diloderm	Endogenous Metabolite , AChE
	Dichlorisone Acetate (Diloderm) is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.		Endogenous Metabolite , AChE
T1429	17α-Hydroxyprogesterone	Hydroxyprogesterone,17-OHP,17-Hydroxyprogesterone	Estrogen/progestogen Receptor , Progesterone Receptor , Endogenous Metabolite
	17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to th...
T2S2043	Dracorhodin perchlorate	Dracorhodin perochlorate,Dracohodin perochlorate	Apoptosis , Others
	Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts in a dose-and time-dependent manner, arresting cell cycle at G1 phase, may as a candidate for anti-breast cancer. Dracorhodin perchlorate...		Apoptosis , Others
T5S2343	Acetylshikonin	Acetyl shikonin	Others , P450 , AChE
	1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang...		Others , P450 , AChE
TN3537	Braylin		IL Receptor , TNF , NF-κB
	Braylin has anti-inflammatory, antinociceptive and immunomodulatory effects, which possibly act through the glucocorticoid receptor activation and by inhibition of the transcriptional activity of NF-ÎºB. Braylin is also ...		IL Receptor , TNF , NF-κB
T13517	Allotetrahydrocortisol	5a-Tetrahydrocortisol	Others
	Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human.		Others

天然物製品

Prednisolone

T1560

Synonym: Predonine,Hydroretrocortine,Metacortandralone

Target: Glucocorticoid Receptor, Endogenous Metabolite

Desonide

T1168

Synonym: Tridesilon,Locapred,Prednacinolone

Target: Glucocorticoid Receptor

Hydrocortisone

T1614

Synonym: Cortisol

Target: Glucocorticoid Receptor, Endogenous Metabolite

Triamcinolone

T0798

Synonym: Fluoxyprednisolone,Aristocort,Rodinolone

Target: Glucocorticoid Receptor, COX

Cortisone

T2884

Synonym: Kendall's compound E,17-Hydroxy-11-dehydrocorticosterone

Target: Glucocorticoid Receptor, Endogenous Metabolite

Cortisone acetate

T0034

Synonym: Cortisone 21-acetate,NSC 49420

Target: Glucocorticoid Receptor, Endogenous Metabolite

Hydrocortisone acetate

T1243

Synonym: Cortisol 21-acetate,Hydrocortisone 21-acetate

Target: Glucocorticoid Receptor, Annexin A, Endogenous Metabolite

(20S)-Protopanaxatriol

T2810

Synonym: 20(S)-APPT,g-PPT

Target: Apoptosis, Estrogen Receptor/ERR, Glucocorticoid Receptor, Estrogen/progestogen Receptor, Liver X Receptor

Cortodoxone

T2748

Synonym: 11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol

Target: Glucocorticoid Receptor, Endogenous Metabolite

Corticosterone

T0948L

Synonym: 17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants)

Target: Glucocorticoid Receptor, Endogenous Metabolite

Medroxyprogesterone Acetate

T1261

Synonym: Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,Farlutin,Medroxyprogesterone (acetate)

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, Androgen Receptor, Endogenous Metabolite

Actriol

T1683

Synonym: Epiestriol

Target: Glucocorticoid Receptor

Geldanamycin

T6343

Synonym: NSC 122750

Target: HSP, Influenza Virus, Tyrosine Kinases, Antibacterial, Antibiotic

Dichlorisone Acetate

T0269

Synonym: Diloderm

Target: Endogenous Metabolite, AChE

17α-Hydroxyprogesterone

T1429

Synonym: Hydroxyprogesterone,17-OHP,17-Hydroxyprogesterone

Target: Estrogen/progestogen Receptor, Progesterone Receptor, Endogenous Metabolite

Dracorhodin perchlorate

T2S2043

Synonym: Dracorhodin perochlorate,Dracohodin perochlorate

Target: Apoptosis, Others

Acetylshikonin

T5S2343

Synonym: Acetyl shikonin

Target: Others, P450, AChE

Braylin

TN3537

Synonym:

Target: IL Receptor, TNF, NF-κB

Allotetrahydrocortisol

T13517

Synonym: 5a-Tetrahydrocortisol

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04561	SGK3 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Serine / threonine-protein kinase Sgk3, also known as Serum / glucocorticoid-regulated kinase 3, Serum / glucocorticoid-regulated kinase-like and SGK3, is a cytoplasmic vesicle protein that belongs to the protein kinase ...
TMPY-02248	Myocilin Protein, Human, Recombinant (His)	Human	HEK293
	Myocilin, also known as Trabecular meshwork-induced glucocorticoid response protein, MYOC, and GLC1A, is a protein that contains one olfactomedin-like domain. Myocilin / MYOC may participate in the obstruction of fluid o...
TMPJ-00110	GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)	Mouse	Human Cells
	Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The p...
TMPY-06836	NR3C1 Protein, Human, Recombinant (His)	Human	E. coli
	NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene. This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements ...
TMPJ-00432	GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
	TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cytokine binds to TNFRSF18/AITR/GITR. It regulates T-cell res...
TMPJ-01319	TINAGL1 Protein, Human, Recombinant (His)	Human	Human Cells
	TINAGL1 is a secreted protein and contains one SMB (somatomedin-B) domain. TINAGL1 is expressed in aorta, lymph nodes, heart, bone marrow, placenta, lung, kidney, skeletal muscle, pancreas, thyroid, adrenal gland and so ...
TMPY-01117	MRAP Protein, Human, Recombinant (hFc)	Human	HEK293
	MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain,...
TMPH-00844	HSD11B2 Protein, Human, Recombinant (His)	Human	Yeast
	Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
TMPK-01064	GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due...
TMPK-00054	GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated	Human	HEK293
	Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due...
TMPK-00132	GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His & Avi), Biotinylated	Human	HEK293
	GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involv...
TMPK-00133	GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His)	Human	HEK293
	GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involv...
TMPY-03259	Calreticulin Protein, Human, Recombinant (His)	Human	HEK293
	Calreticulin is a multifunctional protein. It acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering...
TMPK-00053	GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)	Human	HEK293
	Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due...
TMPK-01086	GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His)	Mouse	HEK293
	GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involv...
TMPK-01260	GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (aa 20-156, His)	Cynomolgus	HEK293
	GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involv...
TMPY-03258	Calreticulin Protein, Human, Recombinant (hFc)	Human	HEK293
	Calreticulin is a multifunctional protein. It acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering...
TMPY-06327	Calreticulin Protein, Human, Recombinant	Human	HEK293
	Calreticulin is a multifunctional protein. It acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering...
TMPY-01383	PRMT6 Protein, Human, Recombinant (His & Flag)	Human	HEK293
	Protein arginine N-methyltransferase 6, also known as Histone-arginine N-methyltransferase PRMT6, PRMT6, and HRMT1L6, is a member of the protein arginine N-methyltransferase family and PRMT6 subfamily. PRMT6 is highly ex...
TMPY-05329	Cortisol Binding Globulin Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Corticosteroid-binding globulin (CBG), also known as SerpinA6, is a non-inhibitory member of the serine proteinase inhibitor (serpin) superfamily. It is the high-affinity transport protein for glucocorticoids in vertebra...
TMPY-02041	Cortisol Binding Globulin Protein, Human, Recombinant (His)	Human	HEK293
	Corticosteroid-binding globulin (CBG), also known as SerpinA6, is a non-inhibitory member of the serine proteinase inhibitor (serpin) superfamily. It is the high-affinity transport protein for glucocorticoids in vertebra...
TMPY-06702	Cortisol Binding Globulin Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293
	Corticosteroid-binding globulin (CBG), also known as SerpinA6, is a non-inhibitory member of the serine proteinase inhibitor (serpin) superfamily. It is the high-affinity transport protein for glucocorticoids in vertebra...
TMPY-02107	Cortisol Binding Globulin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Corticosteroid-binding globulin (CBG), also known as SerpinA6, is a non-inhibitory member of the serine proteinase inhibitor (serpin) superfamily. It is the high-affinity transport protein for glucocorticoids in vertebra...