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Search Results for " immune response "

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阻害剤

天然化合物

122

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T6828	ZL0420		Epigenetic Reader Domain
	ZL0420 is a potent and selective bromodomain-containing protein 4 ( BRD4 ) inhibitor with nanomolar binding affinities to bromodomains (BDs) of BRD4. ZL0420 has IC 50 values of 27 nM against BRD4 BD1 and 32 nM against B...		Epigenetic Reader Domain
T6859	I-BRD9	GSK602	Epigenetic Reader Domain
	I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.		Epigenetic Reader Domain
T3146	BMS-202	PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2	Apoptosis , PD-1/PD-L1
	BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.		Apoptosis , PD-1/PD-L1
T34406	RS 0481	RS-0481,RS0481
	RS 0481 modulates the immune response and rebuilds lymphocyte populations damaged by tumor growth in animals.
TP1029	Thymalfasin	Thymosin α1	Others
	Thymalfasin (Thymosin α1) (thymosin-alpha 1) is an immunomodulating agent able to enhance the Thl immune response.		Others
T10389L	Aspartyl-alanyl-diketopiperazine acetate	DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base)	Others
	Aspartyl-alanyl-diketopiperazine acetate (DA-DKP) (DA-DKP) can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy.		Others
T21444	Diphenylcyclopropenone	DPCP,Diphencyprone	Others
	Diphenylcyclopropenone (DPCP) is a topical drug used to treat alopecia areata, alopecia totalis, and refractory warts. Diphencyprone acts as a local stimulator that triggers an immune response against the action of autor...		Others
T0134	Imiquimod	R 837,S-26308	SARS-CoV , TLR , Autophagy , HSV
	Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist.		SARS-CoV , TLR , Autophagy , HSV
T74140	β-D-Glucan		Others
	β-D-Glucan is a compound that targets tumor-associated macrophages with antitumor activity and modulates the immune response in necrotizing pancreatitis.		Others
T9107	NP-G2-044		Others
	NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.		Others
T78525	IRG1-IN-1		Others
	IRG1-IN-1 is an itaconic acid derivative with the ability to inhibit the activity of Immune Response Gene 1 (IRG1) and is suitable for use in the field of cancer, inflammation and autoimmune disease research.		Others
T23371	SMER3	SMER 3	Others , Ligand for E3 Ligase
	SMER3 is an inhibitor of the Skp1-Cullin-F-box (SCF)(Met30) ubiquitin ligase, a member of the SCF E3-ligase family, which regulates diverse cellular processes including transcription, cell-cycle control and immune respon...		Others , Ligand for E3 Ligase
T40112	PROTAC PD-1/PD-L1 degrader-1	PROTAC PD-1/PD-L1 degrader-1	PROTACs
	PROTAC PD-1/PD-L1 degrader-1, a Cereblon E3 ligand-based compound, is a PD-1/PD-L1 PROTAC that effectively inhibits the interaction between PD-1 and PD-L1 with an IC50 value of 39.2 nM. It successfully restores the suppr...		PROTACs
T73133	FGF22-IN-1		Others
	FGF22-IN-1 is a potential CD4 N-terminal immunoglobulin variable region-like domain (CD4 D1) inhibitor.FGF22-IN-1 inhibits the interaction between CD4 and major histocompatibility complex (MHC) class II proteins and supp...		Others
T50107	Neuroprotective agent 1		Others
	ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate is a synthetic compound belonging to the curcumin family. It is involved in the regulation of immune response and inflammation through ...		Others
T38041	(R)-3-hydroxy Myristic Acid
	Lipopolysaccharides (LPS) are components of the cell walls of Gram-negative bacteria. LPS is composed of polysaccharides and lipid A, where lipid A is a phosphoglycolipid containing acyl chains composed of 10 to 16 carbo...
T6964	Resiquimod	R848,S28463	HCV Protease , TLR
	Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and acti...		HCV Protease , TLR
T77635	LSD1-IN-27		Histone Demethylase , PD-1/PD-L1
	LSD1-IN-27 is a potent LSD1 inhibitor with an IC50 value of 13 nM.LSD1-IN-27 inhibited the stemness and migration of gastric cancer cells.LSD1-IN-27 inhibited the expression of PD-L1 in BGC-823 and MFC cells.LSD1-IN-27 p...		Histone Demethylase , PD-1/PD-L1
T7055	Bz-RS-ISer(3-Ph)-Ome	Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate	Others , HIV Protease
	Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size o...		Others , HIV Protease
T74485	STC314		Others
	STC314 is an anti-infective agent that reverses organ damage caused by excessive immune response by neutralizing extracellular histones and neutrophil trapping networks, and can be used in the study of sepsis and acute r...		Others
T19468	Nafocare B1	Methylfurylbutyrolactone	Others
	Nafocare B1 is a modifier of synthetic immune biological response.		Others
T74760	Polyinosinic acid
	Polyinosinic acid, a single-stranded homonucleic acid and a Toll-like Receptor 3 (TLR3) agonist, enhances the cellular immune response through TLR3 and TRIF. It holds potential applications in immune regulation [1].
T22862	Imiquimod maleate		Others
	Imiquimod maleate is an immune response modifier. It acts as a toll-like receptor 7 agonists and is commonly used topically to treat warts on the skin of the genital and anal areas.		Others
T40473	RCRAMP (rat)
	rCRAMP (rat), the rat cathelin-related antimicrobial peptide, plays a crucial role in the antibacterial activity found in rat brain peptide/protein extracts. As a potential key player in the innate immune system of the r...
T83842	LHC165 hydrate
	LHC165, a toll-like receptor 7 (TLR7) agonist, stimulates the immune system's response by activating TLR7.
T80962	TPNQRQNVC	LRH-1 peptide
	TPNQRQNVC, a nonapeptide epitope of HLA-B0702, induces a CD8+ T cell immune response [1].
T39187	Gliadin p31-43	Gliadin p31-43
	Gliadin p31-43, an undigested peptide derived from gliadin, prompts an innate immune response in the intestine and disrupts endocytic trafficking. Moreover, its utilization in celiac disease research has proven beneficia...
T70594	Gliotoxin monoacetate
	Gliotoxin monoacetate is a toxin found in Aspergillus. It induces apoptosis in cervical cancer cells and chondrosarcoma cells, suppresses the adaptive immune response in leukocytes, and inhibits the proteasome in Plasmod...
T36595	4-epi-Chlortetracycline (hydrochloride)
	Chlortetracycline is an analog of tetracycline , a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects...
T74701	A18-Iso5-2DC18
	A18-Iso5-2DC18 (compound A18), a lipidoid, enhances mRNA protein expression and induces a robust immune response [1].
T82925	Baloramotide
	Baloramotide, a recombinant protein comprising 182 amino acids from NY-ESO-1, enhances the immune response to tumors [1].
T31963	Glyco-lipid	Glycolipid,Glyco lipid
	Glycolipids are lipids with a carbohydrate attached by a glycosidic (covalent) bond. Their role is to maintain the stability of the cell membrane and to facilitate cellular recognition, which is crucial to the immune res...
T72830	TLR8 agonist 5
	TLR8 Agonist 5, exhibiting potent efficacy as a TLR8 agonist, demonstrates an EC50 of 20 nM in HEK-Blue hTLR8, effectively activating the immune response.
T68594	NFAT:AP-1 inhibitor-10
	NFAT:AP-1 inhibitor-10 is a novel inhibitor of the NFAT:AP-1:DNA interaction on the ARRE-2 element, binding to DNA in a sequence-selective manner and inhibiting the transcription of the Il2 gene and several other cyclosp...
T11701	J22352		Caspase
	J22352, a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM, enhances anticancer effects in glioblastoma by promoting HDAC6 degradation. It does so by inhibiti...		Caspase
T25749	L-NIL dihydrochloride	L-NIL HCl,N-Iminoethyl-L-lysine dihydrochloride
	L-NIL HCl is a relatively selective iNOS inhibitor (IC50s: 0.4-3.3, 8-38, and 17-92 µM for iNOS, eNOS, and nNOS). L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical r...
T36984	Cyclic di-IMP (sodium salt)
	Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP . C-di-IMP has adjuvant properties when co-administered with ...
T82381	Fmoc-Thr(GalNAc(Ac)3-β-D)-OH
	Fmoc-Thr(GalNAc(Ac)3-β-D)-OH impedes the proliferation of cancer cells by selectively interacting with complex oncogenic pathways and enhancing the immune response [1].
T78198	DRI-C21041 (DIEA)
	DRI-C21041 DIEA serves as an inhibitor of CD40/CD40L interaction, exhibiting an inhibitory concentration (IC50) of 0.31 μM. It effectively suppresses the immune response triggered by alloantigen [1].
T79193	DRI-C21041
	DRI-C21041 is a potent inhibitor of the CD40/CD40L interaction, demonstrating an inhibitory concentration 50 (IC50) value of 0.31 μM. It effectively suppresses the immune response triggered by alloantigen [1].
T82311	Gliadin p31-43 TFA
	Gliadin p31-43 TFA, an undigested gliadin peptide, triggers an innate immune response in the intestine and disrupts endocytic trafficking, serving as a useful agent for celiac disease research [1] [2].
T78019	Nangibotide TFA	LR12 TFA
	Nangibotide TFA, a TREM-1 receptor inhibitor, modulates the innate immune response and attenuates both systemic and localized inflammatory reactions in rodent models of myocardial ischemia-reperfusion [1].
T79194	DRI-C25441
	DRI-C25441 is a potent inhibitor of the CD40-CD40L interaction, exhibiting an IC50 value of 0.36 μM, and is capable of suppressing the immune response triggered by alloantigen [1].
T81114	Spns2-IN-1		LPL Receptor
	Spns2-IN-1 is a potent Spns2 inhibitor, effectively impeding Spns2-dependent S1P transport with an IC50 value of 1.4±0.3 μM, crucial for modulating the immune response [1].		LPL Receptor
T70268	3A-MPLA
	Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4). It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tu...
T62254	TLR9-IN-1
	TLR9-IN-1 is a selective and potent TLR9 inhibitor that acts on human TLR9 (IC50: 7 nM). TLR9-IN-1 can be used in the study of adverse immune response-related diseases.
T81707	Nangibotide	LR12
	Nangibotide, a TREM-1 receptor inhibitor, modulates the innate immune response and has demonstrated the potential to reduce systemic and localized inflammatory reactions in rodent models of myocardial ischemia-reperfusio...
T27192	DMI-9523	DA-DKP,Ampion,DMI 9523,DM-9523
	DMI-9523 is nuclear factor NF-κB activation inhibitor. Antigen-stimulated human T lymphocytes produce significantly lower quantities of interferon-gamma and tumor necrosis factor-alpha after stimulation in vitro in the p...
T38283	Tetracosanoyl-sulfatide	C24 3'-sulfo Galactosylceramide (d18:1/24:0)
	Tetracosanoyl-sulfatide is an endogenous sulfated glycolipid, which are also known as sulfatides . Tetracosanoyl-sulfatide is the major sulfatide in mature myelin in the central and peripheral nervous systems. Levels of ...
T74348	HE-S2		PD-1/PD-L1
	HE-S2, an antibody-drug conjugate, elicits a potent antitumor immune response by inhibiting the PD-1/PD-L1 interaction and stimulating the Toll-like receptor 7/8 (TLR7/8) signaling pathway, resulting in significant antit...		PD-1/PD-L1

Compounds

ZL0420

T6828

Synonym:

Target: Epigenetic Reader Domain

I-BRD9

T6859

Synonym: GSK602

Target: Epigenetic Reader Domain

BMS-202

T3146

Synonym: PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2

Target: Apoptosis, PD-1/PD-L1

RS 0481

T34406

Synonym: RS-0481,RS0481

Aspartyl-alanyl-diketopiperazine acetate

T10389L

Synonym: DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base)

Target: Others

Diphenylcyclopropenone

T21444

Synonym: DPCP,Diphencyprone

Target: Others

Imiquimod

T0134

Synonym: R 837,S-26308

Target: SARS-CoV, TLR, Autophagy, HSV

Target: Others, Ligand for E3 Ligase

PROTAC PD-1/PD-L1 degrader-1

T40112

Synonym: PROTAC PD-1/PD-L1 degrader-1

Neuroprotective agent 1

T50107

Synonym:

Target: Others

(R)-3-hydroxy Myristic Acid

Target: HCV Protease, TLR

LSD1-IN-27

T77635

Synonym:

Target: Histone Demethylase, PD-1/PD-L1

Bz-RS-ISer(3-Ph)-Ome

T7055

Synonym: Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate

Target: Others, HIV Protease

Synonym: Methylfurylbutyrolactone

Synonym: LRH-1 peptide

Target:

Gliadin p31-43

T39187

Synonym: Gliadin p31-43

Target:

Gliotoxin monoacetate

T70594

Synonym:

Target:

4-epi-Chlortetracycline (hydrochloride)

Synonym: Glycolipid,Glyco lipid

NFAT:AP-1 inhibitor-10

L-NIL dihydrochloride

T25749

Synonym: L-NIL HCl,N-Iminoethyl-L-lysine dihydrochloride

Target:

Cyclic di-IMP (sodium salt)

T36984

Synonym:

Target:

Fmoc-Thr(GalNAc(Ac)3-β-D)-OH

Synonym: DA-DKP,Ampion,DMI 9523,DM-9523

Target:

Tetracosanoyl-sulfatide

T38283

Synonym: C24 3'-sulfo Galactosylceramide (d18:1/24:0)

カタログ番号	製品名	別名	ターゲット
T4940	3-Methylhistamine dihydrochloride		Others , Endogenous Metabolite
	N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histamine metabolite is generally less hampere...		Others , Endogenous Metabolite
T14063	7α,25-Dihydroxycholesterol	7α,25-OHC	EBI2/GPR183 , Endogenous Metabolite
			EBI2/GPR183 , Endogenous Metabolite
T4A2462	Telocinobufagin	Telobufotoxin,Telocinobufogenin	Others
	1. Telocinobufagin (Telobufotoxin) is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the survival time of FIST-immunized mice chall...		Others
T5S0993	Kurarinone		BCL , Others , IκB/IKK , TNF , NF-κB , JAK , STAT
	Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong inhibitory effect on immune responses. Kurarinone may ameli...		BCL , Others , IκB/IKK , TNF , NF-κB , JAK , STAT
T1183	Retinol	all-trans-Retinol,Vitamin A,Vitamin A1,Alphalin	Others
	Retinol (Alphalin) and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune r...		Others
T4S1469	Cucurbitacin IIb		Apoptosis , Others
	1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-i...		Apoptosis , Others
T2563	Acetyl-L-carnitine hydrochloride	Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride	Others , Endogenous Metabolite
	Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur...		Others , Endogenous Metabolite
T3S1612	Kuwanon G	Moracenin B,Kuwanone G	Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase
	1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a...
T7009	Soyacerebroside II		IL Receptor , Calcium Channel
	Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion. Soyacerebrosides I and II have modulating the cellular immune response effects, they show obvious inhibitory activity on IL-18 secretion in human peripheral...		IL Receptor , Calcium Channel
T13606L	CGAMP disodium
	cGAMP disodium is a cyclic dinucleotide (CDN) found in bacteria that acts as an endogenous second messenger affecting interferon production in response to cytoplasmic DNA. cGAMP disodium cascades signals from type I inte...
T34295	Resiniferatoxin	RTX,[3H]resiniferatoxin	IL Receptor
	Resiniferatoxin ([3H]resiniferatoxin) inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in studies about the modulator of the immune response.		IL Receptor

天然物製品

3-Methylhistamine dihydrochloride

T4940

Synonym:

Target: Others, Endogenous Metabolite

7α,25-Dihydroxycholesterol

T14063

Synonym: 7α,25-OHC

Target: EBI2/GPR183, Endogenous Metabolite

Telocinobufagin

T4A2462

Synonym: Telobufotoxin,Telocinobufogenin

Target: BCL, Others, IκB/IKK, TNF, NF-κB, JAK, STAT

Retinol

T1183

Synonym: all-trans-Retinol,Vitamin A,Vitamin A1,Alphalin

Target: Apoptosis, Others

Acetyl-L-carnitine hydrochloride

T2563

Synonym: Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride

Target: Others, Endogenous Metabolite

kuwanon G

T3S1612

Synonym: Moracenin B,Kuwanone G

Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase

Soyacerebroside II

T7009

Synonym:

Target: IL Receptor, Calcium Channel

Synonym: RTX,[3H]resiniferatoxin

Target: IL Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01464	IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)	Human	HEK293 Cells
	Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or m...
TMPY-06981	IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)	Human	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-02904	TLR4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans...
TMPY-00322	DEC-205 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp...
TMPJ-00387	IL-4R alpha Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions a...
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)	Human	E. coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of...
TMPY-06983	IFN gamma Protein, Human, Recombinant (E. coli)	Human	E. coli
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPY-01648	TREML2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like...
TMPH-02271	BTK Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activatio...
TMPH-02937	TLR11 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. TLR11 Protein, Mouse, Recombinant (His & Myc) ...
TMPH-01552	IRF1 Protein, Human, Recombinant (GST & His)	Human	Baculovirus Insect Cells
	Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections,...
TMPK-01231	CLEC2D Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclamps...
TMPH-02493	ADAMDEC1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	May play an important role in the control of the immune response and during pregnancy. ADAMDEC1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight...
TMPK-01230	CLEC2D Protein, Human, Recombinant (hFc & Avi)	Human	HEK293 Cells
	C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclamps...
TMPH-02100	Serpin B4 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	May act as a protease inhibitor to modulate the host immune response against tumor cells. Serpin B4 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted ...
TMPH-03207	IL-2 Protein, Rabbit, Recombinant (His)	Rabbit	E. coli
	Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes...
TMPH-01984	CLECL1P Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	May function in mediating immune cell-cell interactions. May act as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation. May play a role in the interaction of dendritic cells with T-cells and the ce...
TMPJ-00665	ADAMDEC1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ADAM DEC1 protein is expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. ADAM DEC1 is induced during DC maturati...
TMPJ-00291	IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to...
TMPH-02442	IL-2 Protein, Rhesus macaque, Recombinant (His & Myc & SUMO)	Rhesus	E. coli
	Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes...
TMPH-01550	Interferon kappa/IFNK Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pa...
TMPJ-00440	BTNL4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Butyrophilin-like 4, also known as BTLN4, BTN3A3 (human) and BTN3A2 (rat) is an approximately 65 kDa member of the butyrophilin family that may play a role in immune regulation. BTNL4 shows striking sequence similarity t...
TMPJ-01252	CLEC2D Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Sensing tissue damage is an ancient function of immune cells that is central to the regulation of inflammation, tissue repair, and im...
TMPK-00181	PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated	Mouse	HEK293 Cells
	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the ...
TMPH-02585	ACOD1 Protein, Mouse, Recombinant (His & Myc)	Mouse	Baculovirus Insect Cells
	Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory inna...
TMPH-01021	BTN3A1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells ...
TMPK-00688	PD-1 Protein, Canine, Recombinant (aa 25-170, hFc)	Canine	HEK293 Cells
	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the ...
TMPH-01020	BTN3A1 Protein, Human, Recombinant (Yeast, His)	Human	P. pastoris (Yeast)
	Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells ...
TMPK-00180	PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated	Human	HEK293 Cells
	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the ...
TMPH-01133	Complement C8b Protein, Human, Recombinant (His)	Human	E. coli
	Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Complement C8b Protein, Human, Recombinant (His) ...
TMPK-01201	BPIFA1/LUNX Protein, Human, Recombinant	Human	E. coli
	Bactericidal/permeability-increasing fold containing family A, member 1 (BPIFA1) is a secretory protein found in human upper aerodigestive tract mucosa. This innate material is secreted in mucosal fluid or found in submu...
TMPH-02989	ESAT-6 Protein, Mycobacterium bovis, Recombinant (His & Myc)	Mycobacterium bovis	E. coli
	A secreted protein. Acts as a strong host T-cell antigen. Plays a number of roles in modulating the host's immune response to infection as well as being responsible for bacterial escape into the host cytoplasm. ESAT-6 Pr...
TMPJ-00175	B7-H4 Protein, Rhesus macaque, Recombinant (hFc)	Rhesus	HEK293 Cells
	B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negat...
TMPY-02597	IL-37 Protein, Human, Recombinant	Human	E. coli
	Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the e...
TMPK-01298	BST2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune res...
TMPJ-01325	TOLLIP Protein, Human, Recombinant (His)	Human	E. coli
	Toll-Interacting Protein (TOLLIP) is a member of the tollip family. TOLLIP localizes to the cytoplasm. It contains one C2 domain and one CUE domain. TOLLIP is an inhibitory adaptor protein for Toll-like receptors (TLR). ...
TMPK-00596	SECTM1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	SECTM1 is a T/NK cell "co-stimulatory" molecule that is expressed in the peripheral blood by neutrophils and monocytes.Human monocytic cells also displayed a pronounced negative regulation of SECTM1 mRNA expression by LP...
TMPK-00126	CLEC4A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effe...
TMPJ-00608	SLAMF9 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse SLAM family member 9(Slamf9) is a single-pass type I membrane protein. The SLAMF9 gene encodes a member of the signaling lymphocytic activation molecule family. The encoded protein is a cell surface molecule that c...
TMPY-00587	GABARAP Protein, Human, Recombinant (His & MBP)	Human	E. coli
	The Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy). GABARAP in tumorigenesis in...
TMPK-00127	CLEC4A Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effe...
TMPY-00248	Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Baculovirus Insect Cells
	LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surfa...
TMPK-00790	Complement factor H/CFH Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations...
TMPJ-00786	ITGB1 Protein, Human, Recombinant (aa 21-728, His)	Human	HEK293 Cells
	Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue ...
TMPJ-01432	CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated	Human	HEK293 Cells
	MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. MUC16 is over-expressed by t...
TMPH-03577	Staphopain B Protein, S. aureus, Recombinant (GST)	Staphylococcus aureus	E. coli
	Cysteine protease that plays an important role in the inhibition of host innate immune response. Degrades host elastin, fibrogen, fibronectin and kininogen. Blocks phagocytosis of opsonised S. aureus by neutrophils and m...
TMPJ-00219	BTN3A2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Butyrophilin subfamily 3 member A2, also known as BT3.2, BTF3, BTF4 and BTN3A2, is a single-pass type I membrane protein. It is a member of the butyrophilin (BTN) family and the immunoglobulin (IG) superfamily. Mature hu...
TMPH-01607	LCE3A Protein, Human, Recombinant (His)	Human	E. coli
	A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and G...
TMPH-02623	DOCK8 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a...
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IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)

TMPJ-01464

Species: Human

Expression System: HEK293 Cells

IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)

TMPY-06981

Species: Human

Expression System: E. coli

TLR4 Protein, Human, Recombinant (His)

TMPY-02904

Species: Human

Expression System: Baculovirus Insect Cells

DEC-205 Protein, Human, Recombinant (His)

TMPY-00322

Species: Human

Expression System: HEK293 Cells

IL-4R alpha Protein, Mouse, Recombinant (hFc)

TMPJ-00387

Species: Mouse

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

TMPJ-01465

Species: Human

Expression System: E. coli

IFN gamma Protein, Human, Recombinant (E. coli)

TMPY-06983

Species: Human

Expression System: E. coli

C-ABL/ABL1 Protein, Human, Recombinant (GST)

TMPY-04396

Species: Human

Expression System: Baculovirus Insect Cells

TREML2 Protein, Human, Recombinant (His)

TMPY-01648

Species: Human

Expression System: HEK293 Cells

BTK Protein, Human, Recombinant (His)

TMPH-02271

Species: Human

Expression System: Baculovirus Insect Cells

TLR11 Protein, Mouse, Recombinant (His & Myc)

TMPH-02937

Species: Mouse

Expression System: E. coli

IRF1 Protein, Human, Recombinant (GST & His)

TMPH-01552

Species: Human

Expression System: Baculovirus Insect Cells

CLEC2D Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPK-01231

Species: Human

Expression System: HEK293 Cells

ADAMDEC1 Protein, Mouse, Recombinant (His)

TMPH-02493

Species: Mouse

Expression System: E. coli

CLEC2D Protein, Human, Recombinant (hFc & Avi)

TMPK-01230

Species: Human

Expression System: HEK293 Cells

Serpin B4 Protein, Human, Recombinant (His & SUMO)

TMPH-02100

Species: Human

Expression System: E. coli

IL-2 Protein, Rabbit, Recombinant (His)

TMPH-03207

Species: Rabbit

Expression System: E. coli

CLECL1P Protein, Human, Recombinant (His & Myc)

TMPH-01984

Species: Human

Expression System: Baculovirus Insect Cells

ADAMDEC1 Protein, Human, Recombinant (His)

TMPJ-00665

Species: Human

Expression System: HEK293 Cells

IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated

TMPJ-00291

Species: Human

Expression System: HEK293 Cells

IL-2 Protein, Rhesus macaque, Recombinant (His & Myc & SUMO)

TMPH-02442

Species: Rhesus

Expression System: E. coli

Interferon kappa/IFNK Protein, Human, Recombinant (His & SUMO)

TMPH-01550

Species: Human

Expression System: E. coli

BTNL4 Protein, Mouse, Recombinant (His)

TMPJ-00440

Species: Mouse

Expression System: HEK293 Cells

CLEC2D Protein, Mouse, Recombinant (His)

TMPJ-01252

Species: Mouse

Expression System: HEK293 Cells

PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated

TMPK-00181

Species: Mouse

Expression System: HEK293 Cells

ACOD1 Protein, Mouse, Recombinant (His & Myc)

TMPH-02585

Species: Mouse

Expression System: Baculovirus Insect Cells

BTN3A1 Protein, Human, Recombinant (E. coli, His)

TMPH-01021

Species: Human

Expression System: E. coli

PD-1 Protein, Canine, Recombinant (aa 25-170, hFc)

TMPK-00688

Species: Canine

Expression System: HEK293 Cells

BTN3A1 Protein, Human, Recombinant (Yeast, His)

TMPH-01020

Species: Human

Expression System: P. pastoris (Yeast)

PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated

TMPK-00180

Species: Human

Expression System: HEK293 Cells

Complement C8b Protein, Human, Recombinant (His)

TMPH-01133

Species: Human

Expression System: E. coli

BPIFA1/LUNX Protein, Human, Recombinant

TMPK-01201

Species: Human

Expression System: E. coli

ESAT-6 Protein, Mycobacterium bovis, Recombinant (His & Myc)

TMPH-02989

Species: Mycobacterium bovis

Expression System: E. coli

B7-H4 Protein, Rhesus macaque, Recombinant (hFc)

TMPJ-00175

Species: Rhesus

Expression System: HEK293 Cells

IL-37 Protein, Human, Recombinant

TMPY-02597

Species: Human

Expression System: E. coli

BST2 Protein, Cynomolgus, Recombinant (His)

TMPK-01298

Species: Cynomolgus

Expression System: HEK293 Cells

TOLLIP Protein, Human, Recombinant (His)

TMPJ-01325

Species: Human

Expression System: E. coli

SECTM1 Protein, Human, Recombinant (hFc)

TMPK-00596

Species: Human

Expression System: HEK293 Cells

CLEC4A Protein, Human, Recombinant (hFc)

TMPK-00126

Species: Human

Expression System: HEK293 Cells

SLAMF9 Protein, Mouse, Recombinant (His)

TMPJ-00608

Species: Mouse

Expression System: HEK293 Cells

GABARAP Protein, Human, Recombinant (His & MBP)

TMPY-00587

Species: Human

Expression System: E. coli

CLEC4A Protein, Mouse, Recombinant (hFc)

TMPK-00127

Species: Mouse

Expression System: HEK293 Cells

Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)

TMPY-00248

Species: Cynomolgus

Expression System: Baculovirus Insect Cells

Complement factor H/CFH Protein, Human, Recombinant (His)

TMPK-00790

Species: Human

Expression System: HEK293 Cells

ITGB1 Protein, Human, Recombinant (aa 21-728, His)

TMPJ-00786

Species: Human

Expression System: HEK293 Cells

CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated

TMPJ-01432

Species: Human

Expression System: HEK293 Cells

Staphopain B Protein, S. aureus, Recombinant (GST)

TMPH-03577

Species: Staphylococcus aureus

Expression System: E. coli

BTN3A2 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00219

Species: Human

Expression System: HEK293 Cells

LCE3A Protein, Human, Recombinant (His)

TMPH-01607

Species: Human

Expression System: E. coli

DOCK8 Protein, Mouse, Recombinant (His)

TMPH-02623

Species: Mouse

Expression System: P. pastoris (Yeast)

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