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T14326 |
AS-35
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Others
|
|
|
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T26091 |
Riparin III
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|
|
|
Riparin III is an alcamide isolated from Aniba riparia that has exhibited effects of antidepressant and anxiolytic activities in acute stress behavioral models. |
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T60097 |
Methyl (E)-sinapate
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Others
|
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Methyl (E)-sinapate is isolated from the Polygala sibirica L.var. megalopha Fr. |
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T38699 |
Piperafizine A
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|
|
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Piperafizine A is isolated from Streptoverticillium aspergilloides and potentiates vincristine antitumor potency. |
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T84295 |
Valeramide
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|
|
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Valeramide is an amide compound isolated from the roots of Ottonia anisum Spreng. |
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T26016 |
R 56865
|
R-56865,R56865 |
Sodium Channel
|
|
R 56865 is a weak potential-operated channel inhibitor that inhibits the late sodium current in human isolated cardiomyocytes. |
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TP1745L |
Ceratotoxin A acetate
|
Ceratotoxin A acetate(150671-04-8 Free base) |
Antibacterial
|
|
Ceratotoxin A acetate is isolated from the accessory gland secretion fluid, with anti-bacterial effects. |
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T20692L |
Schistoflrfamide acetate
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Schistoflrfamide acetate(121801-61-4 Free base) |
Others
|
|
Schistoflrfamide acetate is isolated from the grasshopper, Schistocerca gregaria. Schistoflrfamide acetate elicited an immediate effect on the basal membrane potential of the opalescent tubule gland cells in insects. |
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T24821 |
Spizofurone
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Espizofurona,AG-629 |
Others
|
|
Spizofurone (Espizofurona) has antiulcer activity, protective effect on the gastric mucosa of rats, and can increase alkaline secretion in isolated bullfrog duodenal mucosa. |
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T20166 |
Deltorphin
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Deltorphin A,Dermenkephalin |
Opioid Receptor
|
|
Deltorphin (Dermenkephalin) is Isolated from the skin of Phyllomedusa Sauvage. It also has an affinity to the opioid receptor. |
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TP1114L |
Leucokinin VIII acetate
|
Leucokinin 8 |
Others
|
|
Leucokinin VIII acetate (Leucokinin 8) is an diuretic octapeptide isolated form head extracts of the cockroach. |
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T7615L |
Xenopsin 2TFA(51827-01-1(free base)
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|
Others
|
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Xenopsin(2TFA) is a neurotensin-like octapeptide previously isolated from amphibian skin. |
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T9343 |
N-Cbz-DL-tryptophan
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|
cholecystokinin
|
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N-Cbz-DL-tryptophan is a cholecystokinin receptor antagonist, abolished the response of the isolated heart to CCK-8. |
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T38003 |
Levofloxacin N-oxide
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Others
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Levofloxacin N-oxide is an inactive metabolite of the antibiotic levofloxacin . Levofloxacin N-oxide is also a degradation product of levofloxacin that is formed through exposure to daylight or hydrogen peroxide. |
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T84296 |
4'-Hydroxyflavone
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|
|
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4'-Hydroxyflavone is a flavonoid compound isolated from the roots of Scutellaria baicalensis with anti-inflammatory activity. |
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T7902 |
Ozenoxacin
|
T-3912 |
Antibacterial
|
|
Ozenoxacin (T-3912) is a quinolone antibacterial. It shows potent activities against the main microorganisms isolated from soft tissue and skin infections. |
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T29345 |
2-Ethyl-5-methylphenol
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Others
|
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2-Ethyl-5-methylphenol is an alkylphenol that can be isolated or identified from Penicillium aurantiogriseum, P. verrucosum and P. viridicatum. |
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T20603L |
Ranatensin acetate
|
|
Others
|
|
Ranatensin acetate, a undecapeptide isolated from skin of Rana pipiens, is a naturally occurring bombesin-like peptide. |
|
TP1839L |
Dermaseptin acetate
|
|
Antibacterial
|
|
Dermaseptin acetate, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration[1]. |
|
T3073 |
PF-670462
|
PF670462 |
Casein Kinase
|
|
PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations. |
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TP1365L |
Parasin I acetate(219552-69-9 free base)
|
|
Antibacterial
|
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Parasin I acetate is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus). |
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T22928L |
Locustatachykinin I acetate
|
|
Others
|
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Locustatachykinin I acetate is a substrate for a deamidase in Lacanobia. Locustatachykinin I acetate is an insect tachykinin-related peptide isolated from Locusta migratoria. |
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T126461 |
Aloenin B
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|
|
|
Aloenin B, a compound isolated from the leaves and roots of Aloe vera, has neuroprotective activity against glutamate-induced neuronal death in HT22 cells. |
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T21331 |
SAR-020106
|
|
Chk
|
|
SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme. |
|
TP1070L |
PACAP (1-27), human, ovine, rat acetate
|
PACAP 1-27 acetate,PACAP (1-27), human, ovine, rat acetate(127317-03-7 free base) |
PACAP
|
|
PACAP (1-27), human, ovine, rat acetate (PACAP 1-27 acetate) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats. |
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T2172 |
SQ22536
|
9-(tetrahydrofuran-2-yl)-9h-purin-6-amine,SQ 22536 |
AChR
|
|
SQ22536 (9-(tetrahydrofuran-2-yl)-9h-purin-6-amine) , the adenosine analogue 9-(Tetrahydro-2-furyl)adenine, inhibited adenylate cyclase activity of crude membrane preparations from catfish (Ictalurus melas) and rat isola... |
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TP1116L |
Kinetensin acetate(103131-69-7 free base)
|
Kinetensin (human) acetate |
Neurotensin Receptor
|
|
Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide. |
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TP1019L |
Urechistachykinin I acetate(149097-03-0 free base)
|
Uru-TK I acetate |
Antibacterial
|
|
Urechistachykinin I acetate(149097-03-0 free base) (Uru-TK I acetate) is an invertebrate kalinin-related peptide (TRPs) isolated from thylakoid nematodes. |
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T8182L |
Guan-fu base A hydrochloride(1394-48-5 free base)
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|
P450
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Guan-fu base A hydrochloride is an antiarrhythmic alkaloid was isolated from Aconitum coreanum. Guanfu base A is hydrochloride a CYP2D6 inhibitor of human, monkey, and dog isoforms. |
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T7658 |
Dimethyl DL-Glutamate (hydrochloride)
|
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Others
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Dimethyl DL-glutamate is a cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes. |
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T6855 |
HA15
|
|
Apoptosis
,
GPR
,
Others
,
HSP
,
Autophagy
|
|
HA15 targets specifically BiP/GRP78/HSPA5. HA15 exhibits anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors. |
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TP1472 |
Tyroserleutide
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Others
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Tyroserleutide (YSL), isolated from the degradation products of porcine spleen, is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo.Tyroserleutide inhibits the growth and metastasis of h... |
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T31931L |
Gizzerosine HCl
|
Gizzerosine HCl(89238-78-8 Free base) |
Others
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Gizzerosine 2HCl, a substance produced during the heat treatment of fishmeal, induces histopathological lesions in broiler chicks and increases intracellular cyclic adenosine-3',5'-monophosphate levels in isolated chicke... |
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T8958 |
PU-H54
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GPR
|
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PU-H54 is a purine-based inhibitor of Grp94. It is a Grp94-selective resorcinol-based inhibitor isolated through probing of the exclusive binding region of S2 subpocket in Grp94. |
|
T8802 |
2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-
|
2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-fur |
Serine Protease
|
|
2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urine or synthetically produced. |
|
TP1192L |
Conopressin S acetate(111317-90-9 free base)
|
Con-S acetate |
Vasopressin Receptor
|
|
Conopressin S acetate(111317-90-9 free base) (Con-S acetate) is a natural product isolated from Conus striatus, shows high affinity with vasopressin V1b receptor (AVPR1B), with a Ki of 8.3 nM. |
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TN7044 |
S-(4-Hydroxybenzyl)glutathione
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|
GluR
|
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L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia ela... |
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TP1018L |
Urechistachykinin II acetate
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Urechistachykinin II acetate(149097-04-1 free base),Uru-TK II acetate |
Others
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Urechistachykinin II acetate (Uru-TK II acetate) is an invertebrate rapid kinin-related peptide (TRPs) isolated from carotenoid worms, shows antimicrobial activities without a hemolytic effect |
|
T3631 |
PF-8380
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|
PDE
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PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood). It modulates lysophosphatidic acid (LPA) levels in vivo/vitro by directly inhib... |
|
TP1281L1 |
Bombesin acetate(31362-50-2 free base)
|
|
Bombesin Receptor
|
|
Bombesin acetate is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad (Bombina bombina). It has two known homologs in mammals called neuromedin B and gastrin-releasing peptide. |
|
TP1900L1 |
Hemopressin (human, mouse) acetate
|
Hemopressin (human, mouse) acetate(1314035-51-2 free base) |
Cannabinoid Receptor
|
|
Hemopressin (human, mouse) acetate is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin is orally active, selective and inverse agonist of CB1 cannabino... |
|
TP2315 |
Glatiramer Acetate
|
|
Others
|
|
Glatiramer acetate (GA) is a synthetic amino acid copolymer that is approved for treatment of relapsing remitting multiple sclerosis (RRMS) and clinically isolated syndrome (CIS). |
|
TP1248L |
ACTH 11-24 acetate(4237-93-8 free base)
|
Adrenocorticotropic Hormone (11-24) acetate |
Melanocortin Receptor
|
|
ACTH 11-24 acetate(4237-93-8 free base) (Adrenocorticotropic Hormone (11-24) acetate) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH ... |
|
T67956L |
Litoxetine HCl
|
litoxetine HCL(86811-09-8 Free base) |
5-HT Receptor
|
|
Litoxetine HCl is a selective 5-hydroxytryptamine (5-HT) reuptake inhibitor (SSRI) and mixed 5-hydroxytryptamine antagonist used in the treatment of urinary incontinence. Litoxetine HCl in the absence of antimuscarinic c... |
|
T61338 |
MS023 dihydrochloride
|
MS023 2HCl |
Histone Methyltransferase
|
|
MS023 dihydrochloride (MS023 2HCl) is a selective, cytosolic and highly potent inhibitor of human type I protein arginine methyltransferases (PRMTs) with antitumour activity, inhibits PRMT1, PRMT3, PRMT4, PRMT6, and PRMT... |
|
T30249 |
AZD 7009
|
AZD-7009,AZD7009 |
Sodium Channel
|
|
AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM. AZD 7009 inhibited late sodium current in isolated rabbit atrial and ventricular myocytes, an... |
|
T77245 |
Mannan
|
|
Endogenous Metabolite
|
|
Mannan is isolated from algae, mushrooms, yeast and higher plants and acts as an immunomodulator.Mannan inhibits the pro-inflammatory activity of hepatic macrophages (M1 lineage) with protective effects against many live... |
|
TP1901L1 |
Hemopressin (rat) acetate(568588-77-2 free base)
|
|
Cannabinoid Receptor
|
|
Hemopressin (rat) acetate is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin is orally active, selective and inverse agonist of CB2 cannabinoid recept... |
|
TP1832 |
Gluten Exorphin C
|
|
Opioid Receptor
|
|
Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.Gluten Exorphin C, isolated from the pe... |
|
T6075 |
Epothilone B
|
Patupilone,EPO 906 |
Apoptosis
,
Microtubule Associated
,
Antibiotic
,
Antifungal
|
|
Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, patupilone induces microtubule polymerization and stabilizes microtubules against depolymerization conditi... |
